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2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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Length of Stay Analysis at Neonatal Care Units with Data Science - Preliminary Results 用数据科学分析新生儿护理单位的住院时间——初步结果
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478748
J. Cordeiro, O. Postolache
The paper presents preliminary results to the length-of-stay (LOS) analysis on neonatal intensive care units, taking as base a 10 year dataset that encompasses data from all neonatal Portuguese units. Unlike conventional studies based on statistical analysis, this investigation uses data science techniques, including machine learning hyperparameters optimization automatization and explainable artificial intelligence (XAI) tools, to understand the relevance of factors and their impact on LOS. In this work was designed and implemented an accurate LOS prediction model which results have been included in the paper. Through XAI techniques application, it was already possible to confirm insights claimed by state-of-the-art studies, namely about the importance of birth weight and gestational age for LOS as well as the importance of hospital-acquired infections. The work presents as novelty the weights (quantification) of these factors as well as the introduction of two new factors, which were not considered until now. The study makes part of ongoing work and will continue to provide better insights for better investment LOS in neonatal care units.
本文介绍了新生儿重症监护病房的住院时间(LOS)分析的初步结果,以10年数据集为基础,其中包括来自所有新生儿葡萄牙单位的数据。与基于统计分析的传统研究不同,本研究使用数据科学技术,包括机器学习超参数优化自动化和可解释的人工智能(XAI)工具,来了解因素的相关性及其对LOS的影响。本文设计并实现了一个精确的LOS预测模型,其结果已在文中发表。通过XAI技术的应用,已经有可能确认最新研究所声称的见解,即出生体重和胎龄对LOS的重要性以及医院获得性感染的重要性。该工作新颖地提出了这些因素的权重(量化),并引入了两个新的因素,这是迄今为止没有考虑到的。该研究是正在进行的工作的一部分,并将继续为更好地投资新生儿护理单位的LOS提供更好的见解。
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引用次数: 1
Characterizing On-Road Vibrations in Ontario’s Neonatal Patient Transport 表征安大略省新生儿病人运输的道路振动
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478679
F. Darwaish, S. Redpath, K. Greenwood, C. Aubertin, A. Ibey, A. Chan, J. Green, R. Langlois
Vibration and noise exposure during emergency neonatal ground and air transport are recognized as hazards for the neonate; however, no standardized test environment exists to reliably quantify such exposure with high repeatability. An on-road test was performed to provide a quantitative measurement of on-road vibrations to be used in the development of the standardized test environment. This paper details the ambulance on-road test instrumentation, analysis, and results. On-road findings indicate that neonates experience vibrations that exceed adult standards; that the power spectral density of the acceleration at the neonate contains peaks (at 2 Hz and 9 Hz) in the frequency range humans are most sensitive (1-20 Hz); and that the damped natural frequency of the patient transport system considered is 9.5 Hz.
在新生儿紧急地面和空中运输过程中的振动和噪声暴露被认为是对新生儿的危害;然而,没有标准化的测试环境可以可靠地量化这种高重复性的暴露。为了在标准化测试环境的开发中使用,进行了一次道路测试,以提供道路振动的定量测量。本文详细介绍了救护车的道路试验仪器、分析和结果。在道路上的研究结果表明,新生儿经历的振动超过了成年人的标准;新生儿加速度的功率谱密度在人类最敏感的频率范围(1-20 Hz)内包含峰值(2 Hz和9 Hz);考虑的病人运输系统的阻尼固有频率为9.5 Hz。
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引用次数: 1
A novel Sensitivity Index from the Flow Velocity Variation in Quality Control for PW Doppler: a preliminary study 一种新的PW多普勒质量控制中流速变化灵敏度指标的初步研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478686
Giorgia Fiori, Fabio Fuiano, A. Scorza, M. Schmid, J. Galo, S. Conforto, S. Sciuto
In recent years, the scientific community highlighted how the combination of the progressive evolution of the Ultrasound (US) technologies and the difficulties in retrieving a fixed number of Quality Control (QC) parameters to assess US equipment performance represents a burden in the definition of a shared worldwide standard. Consequently, this preliminary study introduces and investigates a novel parameter for Pulsed Wave (PW) Doppler QC, namely the Average Maximum Velocity Sensitivity (AMVS). The mathematical expression of the parameter hereby presented has a differential nature that prevents AMVS from being dependent on the insonification angle, which is a commonly accepted systematic error source for the accuracy in the PW Doppler maximum velocity estimation. Data have been acquired from three US systems of intermediate technology level, each one equipped with a phased array US probe. Tests have been performed with two different US system settings and two constant flow rate regimes set on a Doppler flow phantom. Despite the limitations encountered, from the results AMVS emerged as a promising parameter for the assessment of US sensitivity. Therefore, further studies are going to be conducted with different Doppler phantom models, on a higher number of US diagnostic systems and probes.
近年来,科学界强调了超声(US)技术的不断发展和检索固定数量的质量控制(QC)参数以评估美国设备性能的困难,这在定义共享的全球标准中是一种负担。因此,本初步研究引入并研究了脉冲波(PW)多普勒质量控制的一个新参数,即平均最大速度灵敏度(AMVS)。本文给出的参数的数学表达式具有微分性质,可以防止AMVS依赖于不相干角,而不相干角是PW多普勒最大速度估计精度的一个普遍接受的系统误差源。数据从三个中等技术水平的美国系统中获取,每个系统都配备了相控阵美国探头。测试采用了两种不同的美国系统设置和在多普勒流模上设置的两种恒定流速模式。尽管遇到了限制,但从结果来看,AMVS成为评估美国敏感性的一个有希望的参数。因此,将在更多的美国诊断系统和探针上使用不同的多普勒幻像模型进行进一步的研究。
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引用次数: 5
A smart face mask based on photoplethysmography for cardiorespiratory monitoring in occupational settings 一种基于光电容积脉搏图的智能面罩,用于职业环境下的心肺监测
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478599
Riccardo Sabbadini, J. D. Tocco, C. Massaroni, E. Schena, M. Carassiti
In recent years, the market dedicated to wearable devices has undergone a strong expansion due to the increasingly development of innovative and personalized technologies for monitoring vital parameters. The COVID-19 pandemic has led the change in daily habits through the introduction of personal protective equipment (e.g., face mask) into everyday routine. The use of an instrumented face mask to monitor heart rate (HR) and respiratory rate (RR) of workers in occupational settings may be useful to better understand the physiological conditions and the presence of environmental and physical stressors.Among many methods used to estimate these two vital signs, photoplethysmography has gained broad acceptance in the scientific community. Several sites have been used to place the photoplethysmographic sensor (e.g., ear lobe and finger-tip) to estimate the above-mentioned physiological parameters. In this paper, we proposed a smart face mask (SFM) instrumented by a photoplethysmographic sensor. This configuration is particularly adequate to be used in those occupational settings which require the use of common input peripherals (e.g., mouse and keyboard) which prompt to fast movement of hands and fingers, limiting the performance of common measurement systems (e.g., smartwatches) due to motion artifacts. The proof of concept of SFM has been conducted by mimicking conditions close to the mentioned occupational settings through the use of a low computational power algorithm. The proposed system showed promising results by returning values in agreement with the reference system mimicking RR in a wide range of values.
近年来,由于创新和个性化的关键参数监测技术的不断发展,可穿戴设备市场经历了强劲的扩张。COVID-19大流行通过将个人防护装备(如口罩)纳入日常生活,导致了日常习惯的改变。使用仪器面罩监测职业环境中工人的心率(HR)和呼吸频率(RR)可能有助于更好地了解生理状况以及环境和物理压力源的存在。在许多用来估计这两个生命体征的方法中,光容积脉搏波描记术已经在科学界得到了广泛的接受。已经使用了几个位置放置光体积脉搏传感器(如耳垂和指尖)来估计上述生理参数。在本文中,我们提出了一种智能面罩(SFM)仪器的光电容积脉搏波传感器。这种配置特别适合用于那些需要使用通用输入外设(例如,鼠标和键盘)的职业设置,这些设置提示手和手指的快速运动,由于运动伪影限制了通用测量系统(例如,智能手表)的性能。通过使用低计算能力算法模拟接近上述职业设置的条件,对SFM的概念进行了证明。该系统返回的值与参考系统在很大范围内模拟RR的值一致,显示出令人满意的结果。
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引用次数: 4
A 300mV-Supply, 144nW-Power, 0.03mm2-Area, 0.2-PEF Digital-Based Biomedical Signal Amplifier in 180nm CMOS 一种300mv电源,144nw功率,0.03mm2-Area, 0.2 pef的180nm CMOS数字生物医学信号放大器
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478709
P. Toledo, H. Klimach, S. Bampi, P. Crovetti
This paper presents a power-efficient Ultra Low Voltage (ULV) Fully-Differential (FD) Digital-Based Operational Transconductance Amplifier for Biomedical signal processing (BioDIGOTA), which digitally processes biological analog signals using CMOS standard-cells. Post-layout simulations, including parasitic effects in 180nm CMOS technology, show that BioDIG- OTA consumes only 144 nW at 300 mV of supply voltage while driving a 20 pF capacitive load, with a power efficiency factor (PEF) lower than 1. The layout occupies 0.03 mm2 total silicon area, excluding I/0 pads. The proposed BioDIGOTA proves that digital-based analog design can be adopted in biomedical signal amplifiers, lowering the total silicon area by 2.3X times compared to the current state of the art landscape while keeping reasonable power and system performance.
本文提出了一种高效节能的超低电压(ULV)全差分(FD)数字操作跨导生物医学信号处理放大器(BioDIGOTA),该放大器使用CMOS标准单元对生物模拟信号进行数字处理。布局后仿真,包括180nm CMOS技术中的寄生效应,表明BioDIG- OTA在300 mV电源电压下仅消耗144 nW,同时驱动20 pF容性负载,功率效率因子(PEF)低于1。该布局不包括I/0焊盘,总硅面积为0.03 mm2。提出的BioDIGOTA证明了基于数字的模拟设计可以应用于生物医学信号放大器,与目前的技术水平相比,将总硅面积降低2.3倍,同时保持合理的功率和系统性能。
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引用次数: 0
Statistical Analysis of Mental Stress During Oral Presentation 口头陈述时精神压力的统计分析
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478721
A. A. Raj, Vaishali Balakarthikeyan, Deepak Vagish, S. Vijayarangan, S. Preejith, M. Sivaprakasam
An oral presentation is a key stressor in a work environment. High levels of stress might abruptly decrease the quality and quantity of information that needs to be delivered to the audience. So it is important to analyze the person’s stress levels and regulate their stress condition for a better result in their delivery of a speech. Heart Rate Variability (HRV) derived from Electrocardiogram (ECG) is a well-established measure for stress analysis of an individual. To analyse stress, ECG data were collected during an oral presentation from 44 subjects. Frequency domain spectral analysis was done to classify the stress regions. The ratio of the Low Frequency to High Frequency (LF/HF) parameter, a widely accepted method of HRV analysis, was calculated every 5 minutes throughout the entire data. The ECG data were collected for 8 hours during the day. The primary statistical analysis was done to understand the patterns and changes that gets reflected due to this activity. 4:30 to 5:30 PM was the time in which the oral presentation was made each ranging from 15 to 25 minutes. Statistical analysis was done for comparison between the oral presentation period and the other time periods. An increase in the LF/HF ratio was observed during the oral presentation. Variations in the median and standard deviation were observed in both data sets. Analysis of variance was done to understand the variation in the subgroup of the data. A comparison box and whisker plot representation is done to show the distribution, its central value and variability between male and female subjects. The distribution was found to be wider for male subjects compared to female subjects. The standard deviation of LF/HF ratio during the oral presentation was significantly higher than during normal working hours. Also, subjects were requested to answer a short questionnaire to understand the cause of mental stress and the results were discussed.
在工作环境中,口头陈述是一个关键的压力源。高度的压力可能会突然降低需要传递给听众的信息的质量和数量。因此,分析人的压力水平和调节他们的压力状况是很重要的,以便在他们的演讲中取得更好的结果。心率变异性(HRV)来源于心电图(ECG)是一种公认的个体压力分析方法。为了分析应激,在口头陈述期间收集了44名受试者的心电图数据。采用频域谱分析方法对应力区进行分类。低频与高频(LF/HF)参数的比值是一种被广泛接受的HRV分析方法,在整个数据中每5分钟计算一次。白天采集8小时心电图数据。主要的统计分析是为了理解由于该活动而反映出来的模式和变化。下午4:30至5:30是口头陈述的时间,每次15至25分钟。对口头陈述期和其他时间段进行了统计分析比较。在口头陈述期间观察到LF/HF比值的增加。在两组数据中均观察到中位数和标准差的变化。进行方差分析以了解数据亚组的变化。用比较盒和须状图表示男女受试者之间的分布、中心值和变异性。研究发现,与女性受试者相比,男性受试者的分布更广。口述时LF/HF比值的标准差显著高于正常工作时间。此外,研究对象还被要求回答一份简短的问卷,以了解精神压力的原因,并对结果进行讨论。
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引用次数: 2
Hydrogen chemoresistive sensor for the analysis of gut health 用于肠道健康分析的氢化学电阻传感器
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478669
A. Gullino, S. Grassini, G. Gugliandolo, K. Moulaee, N. Donato, M. Parvis, L. Lombardo
Hydrogen is a target gas in the assessment of gut health. Several are the approaches to estimate the concentration of this gas, endogenously present in the gut and, of course, in the blood and the exhaled breath. In this paper, development and characterization of a resistive gas sensor for hydrogen monitoring is reported. The sensing material is based on Nb2O5 Pt thin films, obtained by depositing a niobium oxide layer and a platinum one on a tiny alumina substrate, by means of a lab-scale plasma sputtering reactor. The deposited layers were treated with a thermal process at 600 °C for 30 min. The developed devices were characterized in a hydrogen concentration range of 2000 ppm to 80000 ppm, showing promising results.
氢是评估肠道健康的目标气体。有几种方法可以估计这种气体的浓度,这种气体内源性存在于肠道中,当然也存在于血液和呼出的气体中。本文报道了一种用于氢气监测的电阻式气体传感器的研制和表征。传感材料基于Nb2O5 Pt薄膜,通过实验室规模的等离子溅射反应器在微小的氧化铝衬底上沉积氧化铌层和铂层而获得。沉积层在600°C下进行30分钟的热处理。所开发的器件在2000 ppm至80000 ppm的氢浓度范围内进行了表征,显示出令人满意的结果。
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引用次数: 0
Location Independence in Machine Learning Classification of Sitting-Down and Standing-Up Actions using Wi-Fi Sensors 基于Wi-Fi传感器的坐下和站起来动作机器学习分类中的位置独立性
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478778
I. O. Joudeh, Ana-Maria Creţu, R. B. Wallace, R. Goubran, M. Allegue-Martínez, F. Knoefel
The recognition of human activities in real-time remains an important challenge to enable supportive residential well-being assessments. In this paper, we measure and assess patterns associated with dynamic human activities, such as the actions of sitting-down and standing-up, by analyzing Wi-Fi channel state information. Two Wi-Fi sensors are used to capture information about a person’s activities within a limited space. The effect of sensor location and activity location within the space are assessed to study the independence of the proposed solution with respect to these factors. From the acquired data, feature vectors of 168 variables of kurtosis, maximum, maximum peak, mean, minimum, skew, standard deviation, and variance values are calculated. Traditional classifiers are evaluated for the prediction of dynamic sitting and standing activities. Results obtained demonstrate a classification accuracy of 98.5% using a medium Gaussian support vector machine. Deep learning using a bidirectional long short-term memory network is also tested for sequence-to-label and sequence-to-sequence classification from time series of statistical measures. These models achieved accuracies of 90.7% and 85.1%, respectively. The proposed feature extraction and applied classification demonstrate the ability of our solution to not only differentiate between static and motion activities, but also distinguish between the similar motions of standing-up and sitting-down. Therefore, this work goes beyond the state-of-the-art that generally focuses on detecting motion, not distinguishing between similar movements by subjects.
实时识别人类活动仍然是一个重要的挑战,以实现支持性住宅福祉评估。在本文中,我们通过分析Wi-Fi通道状态信息来测量和评估与动态人类活动相关的模式,例如坐下和站起来的动作。两个Wi-Fi传感器用于捕捉一个人在有限空间内的活动信息。评估了传感器位置和活动位置在空间内的影响,以研究所提出的解决方案相对于这些因素的独立性。从获取的数据中,计算出峰度、最大值、最大峰值、平均值、最小值、偏度、标准差和方差值等168个变量的特征向量。传统的分类器被评估用于预测动态的坐着和站立活动。结果表明,使用中高斯支持向量机的分类准确率为98.5%。使用双向长短期记忆网络的深度学习还测试了从时间序列统计度量的序列到标签和序列到序列分类。这些模型的准确率分别为90.7%和85.1%。所提出的特征提取和应用分类表明,我们的解决方案不仅可以区分静态和运动活动,还可以区分站立和坐下的类似运动。因此,这项工作超越了通常专注于检测运动的最先进技术,而不是区分受试者的相似运动。
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引用次数: 3
Capacitive Link for Data Communication Between Free Floating mm-sized Brain Implants 在自由浮动的毫米大小的大脑植入物之间进行数据通信的电容链路
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478592
Xiao Sha, PuYang Zheng, Yasha Karimi, M. Stanaćević
Establishing communication between free floating brain implants is critical in applications that require a population of implants to operate in an organized manner or in a real-time feedback loop. We present a feasibility study of a data transmission link between mm-sized free floating brain implants through capacitive coupling. The proposed capacitive link utilizes metal plates integrated on a bottom and a sidewall of the implant. We demonstrate that the minimum required input power for establishing the data link is 31 nW at the operating frequency of 915 MHz. We demonstrate the feasibility of the data link up to a distance of 2 mm between the implants.
在需要大量植入物以有组织的方式或在实时反馈回路中操作的应用中,在自由浮动的大脑植入物之间建立通信是至关重要的。我们提出了一种通过电容耦合在毫米大小的自由浮动脑植入物之间建立数据传输链路的可行性研究。所建议的电容连接利用集成在植入物的底部和侧壁上的金属板。我们证明,在915 MHz的工作频率下,建立数据链路所需的最小输入功率为31 nW。我们演示了数据链在植入物之间2毫米距离的可行性。
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引用次数: 0
Comparison of Software Packages for the Analysis of Continuous Glucose Monitoring Data 连续血糖监测数据分析软件包的比较
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478698
Agnese Piersanti, Francesco Giurato, L. Burattini, A. Tura, M. Morettini
The use of Continuous Glucose Monitoring (CGM) systems in the management of diabetes is rapidly growing and represents an eligible technology to overcome the limitations of self-monitoring of blood glucose. However, not complete standardization of the CGM data analyses methodologies is limiting the potential of these devices. In the last few years, different software solutions have been proposed to find a common pattern for making CGM data analysis results more interpretable and reproducible. The aim of this study was to compare two of the newest open-source software packages available for CGM data analysis, GLU and iglu. To perform the comparison, CGM data of 9 subjects with type 1 diabetes coming from the open D1NAMO dataset have been analyzed with both software. Metrics available both in GLU and iglu have been compared, namely: Area Under the Curve (AUC), Time Above Range (TAR), Time Below Range (TBR), Time in Range (TIR) and Mean Absolute Deviation (MAD). Mean values for GLU and iglu were: AUC (170 ± 23 vs. 165 ± 27 mg•dl-1); TAR (40 ± 17 vs. 38 ± 21 %); TBR (6 ± 7 % in both); TIR (54 ± 18 vs. 60 ± 21 %), MAD (43 ± 20 vs. 67 ± 28 mg•dl-1). Only MAD was found statistically different between GLU and iglu. In conclusion, this comparison provided an overview of the graphical and computational aspects in CGM analysis provided by GLU and iglu software packages, which could be useful to researchers and clinicians to find a transparent and consistent way of interpreting CGM data.
连续血糖监测(CGM)系统在糖尿病管理中的应用正在迅速增长,它代表了一种克服自我血糖监测局限性的合适技术。然而,CGM数据分析方法的不完全标准化限制了这些设备的潜力。在过去几年中,已经提出了不同的软件解决方案,以找到一种通用模式,使CGM数据分析结果更具可解释性和可重复性。本研究的目的是比较两种最新的开源软件包,GLU和iglu可用于CGM数据分析。为了进行比较,我们使用两种软件对来自D1NAMO开放数据集的9例1型糖尿病患者的CGM数据进行分析。GLU和iglu可用的指标进行了比较,即:曲线下面积(AUC),范围以上时间(TAR),范围以下时间(TBR),范围内时间(TIR)和平均绝对偏差(MAD)。GLU和iglu的平均值分别为AUC(170±23 vs 165±27 mg•dl-1);TAR(40±17% vs. 38±21%);TBR(6±7%);TIR(54±18比60±21%),MAD(43±20比67±28 mg•dl-1)。GLU和iglu之间只有MAD有统计学差异。总之,这一比较提供了GLU和iglu软件包提供的CGM分析的图形和计算方面的概述,这可能有助于研究人员和临床医生找到一种透明和一致的方法来解释CGM数据。
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引用次数: 2
期刊
2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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