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2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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Measurement and Characterization of Hearing Protection Devices in the Presence of Impulse Sound 脉冲声下听力保护装置的测量和特性
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478767
Bruno Tardif, D. Lo, R. Goubran
Impulsive sounds can cause severe hearing damage and even hearing loss. Sound protection devices are widely used to attenuate impulsive sounds and reduce their impact on hearing. Properly measuring and characterizing the sound attenuation is essential when choosing a specific hearing protection device. Currently, hearing protection devices are often characterized using the Impulse Peak Insertion Loss (IPIL) that measures the total attenuation across all frequency bands. IPIL does not provide any information about the spectral attenuation of the device. Human hearing is spectrally sensitive, and the risk of noise-induced hearing damage is frequency-dependent. Therefore, characterizing hearing protection devices has to be done for both the peak and the full audible frequency spectrum from 20 Hz to 20k Hz. In this paper, we propose a novel energy preserving method for estimating the 1/3 octave band insertion loss using the continuous wavelet transform. To do so, we collected gunshot audio sounds from firing a sniper rifle and evaluated the sound attenuation effect of adding a sound protection device (or sound suppressor) to the rifle. The method that we called Wavelets Octave Band Insertion Loss (WOBIL) is compared with existing methods such as the IPIL, the Impulsive Spectral Insertion Loss (ISIL) and the recently published Octave Band Impulse Peak Insertion Loss (OBIPIL).
冲动的声音会造成严重的听力损伤,甚至听力丧失。声音保护装置被广泛用于衰减脉冲声音,降低其对听力的影响。在选择特定的听力保护装置时,正确测量和表征声音衰减是必不可少的。目前,听力保护设备通常使用脉冲峰值插入损耗(IPIL)来测量所有频段的总衰减。IPIL不提供有关器件的光谱衰减的任何信息。人的听力是频谱敏感的,噪声引起的听力损伤的风险是频率相关的。因此,听力保护装置的特征必须在20 Hz到20k Hz的峰值和全可听频谱范围内完成。本文提出了一种利用连续小波变换估计1/3倍频带插入损耗的保能方法。为此,我们收集了狙击步枪射击的声音,并评估了在步枪上添加声音保护装置(或声音抑制器)的声音衰减效果。我们将小波倍频带插入损失(WOBIL)方法与现有的IPIL、脉冲频谱插入损失(ISIL)和最近发表的倍频带脉冲峰值插入损失(OBIPIL)方法进行了比较。
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引用次数: 0
Statistical correlation analysis between kinematic features and clinical indexes and scales for obese patients 肥胖患者运动特征与临床指标及量表的统计相关分析
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478776
G. Cesarelli, L. Donisi, G. Caprio, M. Scioli, A. Biancardi, G. D'Addio
The study of posture and gait abnormalities has revealed over years potential information to improve the rehabilitation outcome of several classes of ill patients; nevertheless, this results still an area of research almost completely unexplored in the case of obese patients. Consequently, this study was designed as a preliminary investigation to determine potential statistical correlations between kinematic features and “gold standard” methodologies in the field, e.g., the Western Ontario and Mc Master University scale and the Barthel index. To this aim, physicians prepared bioelectrical impedance analyses and clinical assessments to evaluate patients' clinical scores, while biomedical engineers have organized Instrumented Stand and Walking tests to quantify several kinematic features using a microelectromechanical system equipped by a series of inertial measurement units. Finally, a statistical correlation analysis has allowed to reveal several features – related to patients’ anticipatory postural adjustments movements and gait – demonstrated a mild and moderate correlation with some clinical indices. In conclusion, this paper presents a novel view to address and design innovative rehabilitation strategies for obese patients.
多年来,姿势和步态异常的研究揭示了改善几类患者康复结果的潜在信息;然而,在肥胖患者的研究中,这一结果仍然是一个几乎完全未被探索的研究领域。因此,本研究被设计为初步调查,以确定运动学特征与该领域的“黄金标准”方法之间的潜在统计相关性,例如,西安大略和麦克马斯特大学量表和Barthel指数。为此,医生准备了生物电阻抗分析和临床评估来评估患者的临床评分,而生物医学工程师组织了仪器站立和行走测试,使用由一系列惯性测量单元配备的微机电系统来量化几个运动学特征。最后,统计相关性分析揭示了几个特征——与患者预期的姿势调整运动和步态相关——与一些临床指标表现出轻度和中度的相关性。综上所述,本文提出了一种新颖的观点来解决和设计肥胖患者的创新康复策略。
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引用次数: 1
Electric field distribution analysis for the design of an electrode system in a 3D neuromuscular junction microfluidic device 三维神经肌肉连接处微流控装置电极系统设计的电场分布分析
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478775
Flavia Forconi, L. Apa, L. D’Alvia, Marianna Cosentino, E. Rizzuto, Z. Prete
Electrical stimulation (ES) highly influences the cellular microenvironment, affecting cell migration, proliferation and differentiation. It also plays a crucial role in tissue engineering to improve the biomechanical properties of the constructs and regenerate the damaged tissues. However, the effects of the ES on the neuromuscular junction (NMJ) are still not fully analyzed. In this context, the development of a specialized microfluidic device combined with an ad-hoc electrical stimulation can allow a better investigation of the NMJ functionality. To this aim, we performed an analysis of the electric field distribution in a 3D neuromuscular junction microfluidic device for the design of several electrode systems. At first, we designed and modeled the 3D microfluidic device in order to promote the formation of the NMJ between neuronal cells and the muscle engineered tissue. Subsequently, with the aim of identifying the optimal electrode configuration able to properly stimulate the neurites, thus enhancing the formation of the NMJ, we performed different simulation tests of the electric field distribution, by varying the electrode type, size, position and applied voltage. Our results revealed that all the tested configurations did not induce an electric field dangerous for the cell vitality. Among these configurations, the one with cylindrical pin of 0.3 mm of radius, placed in the internal position of the neuronal chambers, allowed to obtain the highest electrical field in the zone comprising the neurites.
电刺激对细胞微环境的影响很大,影响细胞的迁移、增殖和分化。它在组织工程中也起着至关重要的作用,以提高生物力学性能的构建和再生受损组织。然而,ES对神经肌肉接点(NMJ)的影响尚未得到充分的分析。在这种情况下,开发一种专门的微流体装置,结合特殊的电刺激,可以更好地研究NMJ的功能。为此,我们对三维神经肌肉连接微流控装置中的电场分布进行了分析,用于设计几种电极系统。首先,为了促进神经细胞与肌肉工程组织之间NMJ的形成,我们设计了三维微流控装置并进行了建模。随后,为了确定能够适当刺激神经突的最佳电极配置,从而促进NMJ的形成,我们通过改变电极类型、尺寸、位置和施加电压对电场分布进行了不同的模拟测试。我们的结果显示,所有测试的配置都不会产生对细胞活力有害的电场。在这些配置中,半径为0.3 mm的圆柱形针放置在神经元室的内部位置,可以在包含神经突的区域获得最高的电场。
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引用次数: 0
Gait Analysis using Wearable E-Textile Sock: an Experimental Study of Test-Retest Reliability 穿戴式电子纺织袜步态分析:重测信度实验研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478702
F. Amitrano, A. Coccia, L. Donisi, G. Pagano, G. Cesarelli, G. D'Addio
Sock is a wearable e-textile sock for gait analysis. It is based on the acquisition and digital processing of the angular velocities of the lower limbs. In this paper we focus on the study of test-retest reliability of this system in measuring spatio-temporal gait parameters. The analysis was simultaneously conducted on data acquired by a multicamera system for gait analysis (SMART-DX 700 by BTS), in order to have reference values. A group of healthy subjects, equipped with both systems, performed four repeated walking tests along an 11 m walkway, consecutively and under constant conditions. The four tests were repeated at preferred, slow and fast self- selected walking speed. The Intraclass Correlation Coefficient (ICC) and Minimum Detectable Change (MDC) were evaluated to assess the repeatability of the measures. ICC values range from moderate to excellent for all gait parameters assessed by smart socks. The novel system presents test-retest reliability values comparable to, if not higher than, those shown by the gold standard. Finally, the results of gait reliability as a function of walking speed show excellent ICCs and very low MDCs for all parameters evaluated on trials at fast velocity, supporting the referenced hypothesis that faster movement is more consistent.
Sock是一种可穿戴的电子纺织品袜子,用于步态分析。它是基于下肢角速度的采集和数字处理。本文重点研究了该系统在测量时空步态参数时的重测信度。同时对多摄像头步态分析系统(BTS的SMART-DX 700)采集的数据进行分析,以便有参考价值。一组健康受试者配备了这两种系统,在恒定条件下连续沿着11米的人行道进行了四次重复行走测试。四项试验分别以自我选择的首选、慢速和快速进行。评估类内相关系数(ICC)和最小可检测变化(MDC)以评估测量的可重复性。智能袜子评估的所有步态参数的ICC值范围从中等到优异。新系统呈现的重测信度值与金标准显示的信度值相当,如果不高于的话。最后,步态可靠性作为步行速度函数的结果显示,在快速度试验中评估的所有参数的ICCs都很好,MDCs很低,支持了更快的运动更一致的参考假设。
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引用次数: 6
Identifying High Risk of Atherosclerosis Using Deep Learning and Ensemble Learning 利用深度学习和集成学习识别动脉粥样硬化的高风险
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478741
Hedieh Hashem Olhosseiny, Mohammadsalar Mirzaloo, M. Bolic, H. Dajani, V. Groza, Masayoshi Yoshida
Atherosclerosis refers to the buildup of plaque on the artery walls. As the disease advances in its further stages, its burden could lead to stroke or heart attack. Atherosclerosis develops gradually, and mild stages of the condition are usually symptomless. Diagnosing patients in their early stages of the disease can facilitate timely clinical interventions enhancing patient’s quality of life by altering the course of the disease. The work presented in this paper is focused on classifying patients who are at high risk of Atherosclerosis using simple diagnosis tools available in every clinic. The final system is a prescreening tool providing the medical practitioners with recommendations regarding the disease. High risk patients can be referred to a cardiologist for further assessments. A dataset of 44 patients was collected including 17 low-risk and 27 high-risk patients. Two different approaches were taken, 1. using deep learning and time series data (ECG signals) 2. using traditional machine learning algorithms and tabular data. In the first approach, a Conv-GRU model was trained using ECG signals collected from patients. This method resulted in an average accuracy of 77% which was computed over 4 folds using cross validation. In the second approach, Stacking, an ensemble learning technique in which the final prediction is obtained by combining the prediction of different machine learning models trained on several attributes readily collected in the clinic, was used. An average accuracy of 81% was achieved using this method.
动脉粥样硬化是指动脉壁上斑块的积聚。随着病情进一步发展,其负担可能导致中风或心脏病发作。动脉粥样硬化是逐渐发展的,病情的轻度阶段通常没有症状。在疾病的早期阶段诊断患者可以通过改变疾病的进程,促进及时的临床干预,提高患者的生活质量。本文提出的工作重点是使用每个诊所可用的简单诊断工具对动脉粥样硬化高风险患者进行分类。最后一个系统是一个预筛选工具,为医生提供有关疾病的建议。高危患者可转诊给心脏病专家作进一步评估。收集了44例患者的数据集,其中低危患者17例,高危患者27例。采取了两种不同的方法:1。使用深度学习和时间序列数据(心电信号)使用传统的机器学习算法和表格数据。在第一种方法中,使用从患者身上收集的心电信号训练卷积神经网络模型。该方法的平均准确度为77%,使用交叉验证计算了4倍以上。在第二种方法中,使用了堆叠(Stacking),这是一种集成学习技术,通过结合在临床中容易收集的几个属性上训练的不同机器学习模型的预测来获得最终预测。该方法的平均准确度为81%。
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引用次数: 1
Ensembling CNNs for dermoscopic analysis of suspicious skin lesions 集成cnn用于可疑皮肤病变的皮肤镜分析
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478760
Yali Nie, M. Ferro, P. Sommella, M. Carratù, S. Cacciapuoti, G. D. Leo, J. Lundgren, G. Fabbrocini
Deep Convolution Neural Networks (CNN) enable advanced methods to predict the skin cancer classes through the automatic analysis of digital dermoscopic images. However, small datasets' availability often allows the models to be characterized by low prediction accuracy and poor generalization ability, which significantly influences clinical decisions. This paper proposes to use an original ensembling of multiple CNNs as feature extractors able to detect and measure skin lesions atypical criteria according to the well-known diagnostic method 7-Point Check List. The experimental results show that the Artificial Intelligence-based model can suitably manage the classification uncertainty of the single CNNs and finally distinguish melanomas from benignant nevi. Diagnostic performance is promising in terms of sensitivity and specificity towards a decision-supporting system used by a dermatologist with low experience during clinical practice.
深度卷积神经网络(CNN)通过对数字皮肤镜图像的自动分析,实现了预测皮肤癌类别的先进方法。然而,由于数据集较小,模型的预测精度较低,泛化能力较差,严重影响临床决策。本文提出使用多个cnn的原始集合作为特征提取器,能够根据著名的7点检查表诊断方法检测和测量皮肤病变的非典型标准。实验结果表明,基于人工智能的模型可以很好地管理单个cnn的分类不确定性,最终区分出黑色素瘤和良性肿瘤。诊断性能是有希望的敏感性和特异性对决策支持系统使用的皮肤科医生在临床实践经验低。
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引用次数: 0
Wirelessly Powered Device for Optical Measurement of Respiration Rate 呼吸速率光学测量无线供电装置
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478773
Yu-Chieh Chen, J. Tsan, Wen-Yen Lin
The accurate measurement of respiration rate in sleeping patients requires the patients to be in a comfortable state. Current measurement systems usually require patients to wear tights because the sensors must be close to the body to enable the acquisition of high-quality measurements. However, tights are uncomfortable when worn for a long period, especially during sleep. Moreover, current systems are marred by poor battery life, which is a major problem for overnight monitoring processes; existing battery designs cannot be integrated into smart clothing, which must be waterproof to protect electronic components during laundry.To solve these problems, this study developed a wireless power– supplied optical respiratory measurement module (wireless-ORM), which can be integrated with cotton clothing for the optical, noncontact measurement of respiratory rate. This module is powered wirelessly, which eliminates the need for a battery and allows for an indefinite power supply. The wireless-ORM can also be easily covered with a waterproof membrane for waterproofing. We fabricated and tested a prototype of the wireless-ORM measuring 197 × 20 × 3 mm3 in volume and 2.8 g in weight. The sensor was determined to function at distances up to 40 mm from the body, meaning that respiration rate could be measured even with thick winter clothes. The wireless-ORM could also receive power wirelessly up to 70 cm from a base station. Due to its small size, the wireless-ORM can be wrapped in plastic for waterproofing to enable its use in smart clothing.
睡眠患者呼吸频率的准确测量需要患者处于舒适的状态。目前的测量系统通常需要患者穿紧身衣,因为传感器必须靠近身体才能获得高质量的测量结果。然而,长时间穿紧身衣很不舒服,尤其是在睡觉的时候。此外,目前的系统受到电池寿命短的影响,这是夜间监测过程的主要问题;现有的电池设计不能集成到智能服装中,智能服装必须是防水的,以便在洗衣时保护电子元件。为了解决这些问题,本研究开发了一种无线供电光学呼吸测量模块(wireless- orm),该模块可与棉质服装集成,实现呼吸速率的光学非接触式测量。该模块是无线供电的,因此不需要电池,并允许无限供电。无线orm也可以很容易地覆盖一层防水膜。我们制作并测试了一个无线orm的原型,体积为197 × 20 × 3毫米,重量为2.8克。该传感器被确定在距离身体40毫米的距离内工作,这意味着即使穿着厚厚的冬衣也可以测量呼吸速率。这种无线orm还可以在距离基站70厘米的地方无线接收电力。由于其体积小,无线orm可以用塑料包裹防水,使其能够用于智能服装。
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引用次数: 0
Efficient feature selection for electroencephalogram-based authentication 基于脑电图认证的高效特征选择
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478700
Nibras Abo Alzahab, M. Baldi, L. Scalise
Opposed to classic authentication protocols based on credentials, biometric-based authentication has recently emerged as a promising paradigm for achieving fast and secure authentication of users. Among the several families of biometric features, electroencephalogram (EEG)-based biometrics is considered as a promising approach due to its unique characteristics. Classification systems based on machine learning allow processing of large amounts of data and performing accurate attribution of each signal to the most relevant group, thus representing an invaluable tool for EEG-based biometrics. This paper provides an experimental evaluation of the performance achievable by EEG-based biometrics employing machine learning. We consider several groups of EEG signals and propose a suitable feature extraction criterion. Then, the extracted features are used along with neural network-based classification algorithms, K Nearest Neighbours (KNN), and eXtreme Gradient Boost (XGBoost) for attributing any EEG signal to a subject. A full feature set and a reduced feature sets are considered and tested on three public data sets. The feature selection criteria are based on a correlation map among features, ANOVA F-test, and logistic regression weights. The results show that the reduced feature sets achieves a significant reduction in computation time over the full feature set, while also providing some improvement in performance.
与基于凭证的经典身份验证协议相反,基于生物识别的身份验证最近成为实现快速和安全的用户身份验证的有前途的范例。在众多生物特征中,基于脑电图(EEG)的生物特征以其独特的特性被认为是一种很有前途的方法。基于机器学习的分类系统允许处理大量数据,并将每个信号准确地归为最相关的组,因此代表了基于脑电图的生物识别技术的宝贵工具。本文对采用机器学习的基于脑电图的生物识别技术所能实现的性能进行了实验评估。我们考虑了几组脑电信号,并提出了合适的特征提取准则。然后,将提取的特征与基于神经网络的分类算法、K近邻(KNN)和极限梯度增强(XGBoost)一起用于将任何EEG信号归因于受试者。在三个公共数据集上考虑和测试完整的特性集和简化的特性集。特征选择标准是基于特征之间的相关性图、方差分析f检验和逻辑回归权重。结果表明,与完整的特征集相比,简化后的特征集大大减少了计算时间,同时性能也有所提高。
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引用次数: 4
A preliminary study on the dynamic characterization of a MEMS microgripper for biomedical applications 生物医学用MEMS微夹持器动态特性的初步研究
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478703
F. Vurchio, Gabriele Bocchetta, Giorgia Fiori, A. Scorza, N. Belfiore, S. Sciuto
This preliminary study concerns the dynamic characterization of a MEMS microgripper for biomedical applications. In particular, a prototype of microgripper, embedded with electrostatic comb-drive actuators, has been powered with a 10V sinusoidal input at different frequencies, 0.5 Hz, 1.0 Hz and 4.0 Hz. The response of the device has been recorded with a trinocular optical microscope, equipped with a digital camera and the recorded videos have been analysed with an in-house software implemented by the authors for the measurement of the comb-drive angular displacement, velocity and acceleration. The uncertainty analysis has been carried out to identify the uncertainty sources that characterize the measurements. Experimental data showed that the maximum angular displacement is (13.2 ± 0.2)•10-3 rad, (13.6 ± 0.2)•10-3 rad and (13.1 ± 0.3)•10-3 rad, the maximum angular velocity is (2.8 ± 0.2)•10-2 rad/s, (5.7 ± 0.4)•10-2 rad/s and (19.9 ± 1.5)•10-2 rad/s, and the angular acceleration is 0.178 ± 0.015 rad/s2, 0.72 ± 0.04 rad/s2 and 6.3 ± 0.7 rad/s2 for 0.5 Hz, 1.0 Hz and 4.0 Hz, respectively. The measurement results have been compared with the expected values from the theoretical model that describes the behaviour of the microgripper: the overall percentage error (PE) between the measured and the expected values at different frequencies is lower than 1%, 1% and 3% for the angular displacement, velocity and acceleration respectively.
本初步研究涉及生物医学应用的MEMS微夹持器的动态特性。特别是,嵌入静电梳子驱动驱动器的微夹钳原型,以不同频率(0.5 Hz, 1.0 Hz和4.0 Hz)的10V正弦输入供电。用装有数码相机的三叉光学显微镜记录了该装置的响应,并用作者开发的内部软件对记录的视频进行了分析,用于测量梳子驱动的角位移、速度和加速度。进行了不确定度分析,以确定测量的不确定度来源。实验数据表明,在0.5 Hz、1.0 Hz和4.0 Hz下,最大角位移为(13.2±0.2)•10-3 rad、(13.6±0.2)•10-3 rad和(13.1±0.3)•10-3 rad,最大角速度为(2.8±0.2)•10-2 rad/s、(5.7±0.4)•10-2 rad/s和(19.9±1.5)•10-2 rad/s,角加速度分别为0.178±0.015 rad/s2、0.72±0.04 rad/s2和6.3±0.7 rad/s2。将测量结果与描述微夹持器行为的理论模型的期望值进行了比较:在不同频率下,角位移、速度和加速度的测量结果与期望值之间的总体百分比误差(PE)分别小于1%、1%和3%。
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引用次数: 6
PARKIBIP Feedback Wearable Rehabilitation Device: Market Analysis and Enhancements PARKIBIP反馈可穿戴康复设备:市场分析和改进
Pub Date : 2021-06-23 DOI: 10.1109/MeMeA52024.2021.9478736
Valentina Pasker, C. Huerta, Samuel Sainz, Darío Santos, F. Simini
Rehabilitation counteracts motor deficiencies in gait disorder of Parkinson's Disease (PD) patients. PARKIBIP is a wearable feedback device that aims to offer a continuous and personalized rehabilitation tool for such people. A survey and external study of PARKIBIP suggest design enhancements. Exploration of its industrial potential shows direct competitors, a first step to conclude that PARKIBIP is suitable for Technological Transfer to a company for commercial dissemination. PARKIBIP is both a home treatment helping device and a clinical data & feedback capture terminal for the electronic medical record. Being wearable technology, PARKIBIP stands out in the present global context as an affordable robotic element with feedback capability connected to the patient's mobile phone.
康复可以抵消帕金森病(PD)患者步态障碍的运动缺陷。PARKIBIP是一种可穿戴反馈设备,旨在为这些人提供持续和个性化的康复工具。PARKIBIP的一项调查和外部研究建议改进设计。对其工业潜力的探索显示了直接竞争对手,这是得出PARKIBIP适合将技术转让给公司进行商业推广的第一步。PARKIBIP既是一种家庭治疗辅助设备,也是一种用于电子病历的临床数据和反馈捕获终端。作为一种可穿戴技术,PARKIBIP作为一种价格合理的机器人元件,与患者的手机相连,具有反馈功能,在当前的全球环境中脱颖而出。
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引用次数: 3
期刊
2021 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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