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Problematic social media use, digital gaming addiction and excessive screen time among Turkish adolescents during remote schooling: implications on mental and academic well-being 土耳其青少年在远程教育期间有问题的社交媒体使用、数字游戏成瘾和屏幕时间过长:对心理和学业健康的影响
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244628
Gresa Çarkaxhiu Bulut, Sebla Gokce
Objective: The present study aimed to describe screen use patterns among Turkish adolescents during the coronavirus disease 19 (COVID-19) pandemic with a special emphasis on social media and digital gaming addiction, and explore how these are linked to adolescents’ mental and academic well-being. Materials and Method: The study sample consisted of 9th to 12th grade students from three public high-schools in Istanbul, Turkey (n=201). Participants were required to complete a comprehensive questionnaire which gathered information about various domains including problematic screen use, attitudes towards online education, and mental/academic well-being during the lockdown period. Results: The overall screen time exhibited a significant increase during the lockdown, with the most common discretionary screen activities being social media use, communication, and watching movies/series (p
目的:本研究旨在描述2019冠状病毒病(COVID-19)大流行期间土耳其青少年的屏幕使用模式,特别强调社交媒体和数字游戏成瘾,并探讨这些与青少年的心理和学业健康之间的关系。材料与方法:研究样本为土耳其伊斯坦布尔三所公立高中的9 - 12年级学生(n=201)。参与者被要求完成一份全面的调查问卷,该问卷收集了有关封锁期间屏幕使用问题、对在线教育的态度以及心理/学业健康等各个领域的信息。结果:在封锁期间,总体屏幕时间显着增加,最常见的自由支配屏幕活动是社交媒体使用,通信和观看电影/连续剧(p
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引用次数: 1
The failure on the effectiveness of formalin on cadaver disinfection and alternative methods 福尔马林对尸体消毒效果的影响及替代方法
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244383
Ozgur Yanilmaz, Mehmet Mucahit Guncu, M. Aksu, Mazhar Ozkan, Umit S. Sehirli
Objective: It was aimed to identify the contaminant and determine the alternative disinfectant detection in the microbial growth observed in various parts of the cadaver stored in the formalin tank in the dissection laboratory of Marmara University Anatomy Department. We also performed a literature review of this unusual pathogen. Materials and Methods: Swab samples were inoculated on agar mediums. After incubation, matrix-assisted laser desorption ionizationtime of flight mass spectrometry (MALDI-TOF MS) analysis was used to identify the isolate from the detected uniform colonies. Sample solution from the cadaver tank, freshly prepared 5% formalin and 0.55% ortho-phthalaldehyde were used to determine the disinfectant sensitivity of the isolate. Results: According to 16s rDNA sequence analysis, it was concluded as Skermanella aerolata with 99% similarity. In the disinfectant susceptibility test, it was observed that S. aerolata and control bacteria could grow in 5% formalin taken from the cadaver tank. No growth was detected in other disinfectants. Conclusion: To prevent cadaver contamination in anatomy laboratories, the quality control of the embalming solutions and indoor air filtration of the dissection rooms should be checked at regular intervals. Members of Skermanella genus have been identified as environmental organisms in several studies, however, recent researches reported this bacterium as a human pathogen.
目的:在马尔马拉大学解剖系解剖实验室福尔马林池中保存的尸体各部位的微生物生长情况下,确定污染物并确定替代消毒剂检测方法。我们还对这种不寻常的病原体进行了文献综述。材料和方法:将拭子样品接种在琼脂培养基上。培养后,使用基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)分析从检测到的均匀菌落中鉴定分离物。使用来自尸体箱的样品溶液、新制备的5%福尔马林和0.55%邻苯二甲醛来测定分离物的消毒剂敏感性。结果:经16s rDNA序列分析,其相似性达99%,为气动斯克马奈菌。在消毒剂敏感性试验中,观察到aerolata和对照细菌可以在取自尸体箱的5%福尔马林中生长。在其他消毒剂中未检测到生长。结论:为防止解剖室尸体污染,应定期检查解剖室防腐液和室内空气过滤的质量控制。Skermanella属的成员在几项研究中被确定为环境生物,然而,最近的研究报道这种细菌是人类病原体。
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引用次数: 0
The relationship between renal functions and multi-drug resistant organisms in patients with ventilator-associated pneumonia 呼吸机相关性肺炎患者肾功能与多药耐药菌的关系
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244732
Omur Ilban, Aysegul Ilban
Objective: Despite the increase in the frequency of multi-drug resistant organism (MDRO) colonisation and infection in dialysis patients, it is not well known whether the risk of multi-drug resistant (MDR) pneumonia increases in mild-to-severe chronic kidney disease patients not undergoing dialysis. Therefore, we aimed to evaluate the relationship between renal functions and the risk of MDR ventilator-associated pneumonia (VAP) and the specific microbial pattern. Patients and Methods: A total of 133 patients who developed VAP were divided according to their renal function into two groups, an estimated glomerular filtration rate of (eGFR) ≥ 60 mL/ min/1.73 m2 (high eGFR, n=65) and eGFR < 60 mL/min/1.73 m2 (low eGFR, n=68). Results: The low eGFR group presented a significantly high MDRO ratio (p
目的:尽管透析患者中多药耐药菌(MDRO)定植和感染的频率增加,但不进行透析的轻至重度慢性肾病患者发生多药耐药(MDR)肺炎的风险是否增加尚不清楚。因此,我们旨在评估肾功能与MDR呼吸机相关性肺炎(VAP)风险和特定微生物模式之间的关系。患者和方法:133例VAP患者根据肾功能分为肾小球滤过率(eGFR)≥60 mL/min/1.73 m2(高eGFR, n=65)和eGFR < 60 mL/min/1.73 m2(低eGFR, n=68)两组。结果:低eGFR组MDRO比值显著增高(p
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引用次数: 0
Evaluation of autonomic nervous system functions by using tilt table test and heart rate variability in epileptic children 应用倾斜试验和心率变异性评价癫痫患儿自主神经系统功能
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244552
Azad Redjepov, Sinem Altunyuva Usta, Y. Yildirim, F. Akalın
Objective: The value of head-up tilt test (HUTT) for differential diagnosis of epilepsy and the autonomic nervous system functions in epileptic children using heart rate variability (HRV) are studied. Patients and Methods: The study group consisted of 16 children with idiopatic/criptogenic epilepsy and 12 controls. Heart rate, PR interval, corrected QT (QTc) interval, QT and QTc dispersion were calculated using 12-lead electrocardiogram (ECG), HRV analysis was performed using the Holter recordings obtained both during HUTT and throughout the day. Time domain parameters, standard deviation of all RR intervals (SDNN), the standard deviation of mean NN intervals in five-minutes recording (SDANN), mean standard deviation of NN intervals in five-minutes recordings (SDNNi), root mean square of successive differences (RMSSD), count divided by the total number of all NN intervals (pNN50) and frequency domain parameters low frequency (LF), high frequency (HF), lowfrequency/ high-frequency ratio (LF/HF) were calculated in both and compared between the two groups. Results: Head-up tilt test was positive in 4 epileptic children (25%), none of controls were positive. The heart rate of the patients were higher than the controls (p=0.015). LF/HF ratio in 24-hour Holter recordings, were significantly lower (1.13±0.6, 1.83±0.7 respectively, p=0.002); the SDANN during HUTT (28.7±20.2, 18.2 ± 19.9 respectively, p=0.024) were significantly higher in the patients than the controls. Conclusion: Head-up tilt test positivity is frequent in epileptic children, and cannot be used in differential diagnosis. HRV calculated both from 24 hour Holter recordings and Holter recordings under orthostatic stress were impaired in favour of parasympathetic system in epileptic children.
目的:利用心率变异性(HRV)研究抬头倾斜试验(HUTT)在癫痫鉴别诊断和癫痫儿童自主神经系统功能方面的价值。患者和方法:研究组包括16名特发性/脚本性癫痫儿童和12名对照组。使用12导联心电图(ECG)计算心率、PR间期、校正QT(QTc)间期、QT和QTc离散度,使用HUTT期间和全天获得的Holter记录进行HRV分析。时域参数、所有RR间期的标准差(SDNN)、五分钟记录中的平均NN间期的标准偏差(SDNN,计算两组患者的心率、高频(HF)、低频/高频比(LF/HF)并在两组之间进行比较。结果:4例癫痫患儿(25%)的抬头倾斜试验呈阳性,对照组无一例呈阳性。患者的心率高于对照组(p=0.015)。24小时动态心电图记录的LF/HF比值显著低于对照组(分别为1.13±0.6、1.83±0.7,p=0.002);HUTT期间患者的SDNN(分别为28.7±20.2、18.2±19.9,p=0.024)显著高于对照组。结论:癫痫患儿抬头倾斜试验阳性率高,不能用于鉴别诊断。根据24小时动态心电图记录和直立应激下的动态心电图记录计算的HRV受损,有利于癫痫儿童的副交感神经系统。
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引用次数: 0
Molecular analysis of human adenoviral keratoconjunctivitis cases: Results of a 2-year survey 人类腺病毒性角结膜炎病例的分子分析:2年调查结果
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244369
Ayfer Guner, Rabia Can Sarınoğlu, F. Aydin, S. Akkaya Turhan, M. Kuşkucu, A. E. Toker, Aysegul Karahasan Yagci
Objective: This study aimed to determine the adenovirus genotypes and their epidemiological features between January 2018 and November 2019, in Istanbul, Turkey. Material and Methods: Conjunctival swab samples were obtained from patients who were clinically diagnosed with keratoconjunctivitis. Samples were screened with an Adeno Detector kit (Rapid Pathogen Screening, RPS Inc., South Williamsport, PA). Nucleic acid extraction and amplification were performed with the ADENOVIRUS ELITe MGB® kit in the ELITe In Genius instrument (Elitech Group, Torino, Italy). For subtyping of the strains, sequencing primers targeted the ‘Hypervariable Region 7’ (HVR-7) of the hexon gene were used. DNA sequence analysis (n:72) was performed with ABI PRISM® 3100 Genetic Analyzer (Applied Biosystems, USA), and subtyping was done by BLAST analysis. Results: The median viral load in the samples (n: 77) was 7 log10 copies/mL (IQR: 4.5-7.4 log10 copies/mL). The clinical finding score was found to be significantly higher in the high viral load group (Adenovirus DNA≥6 Log 10 copies/mL) than in the low viral load group (Adenovirus DNA
目的:了解2018年1月至2019年11月土耳其伊斯坦布尔地区腺病毒基因型及其流行病学特征。材料和方法:从临床诊断为角膜结膜炎的患者中获得结膜拭子样本。样品用腺病毒检测试剂盒(快速病原体筛选,RPS公司,South Williamsport, PA)筛选。在ELITe in Genius仪器(ELITe Group, Torino, Italy)中使用腺病毒ELITe MGB®试剂盒进行核酸提取和扩增。采用针对六邻体基因“高变区7”(HVR-7)的测序引物进行分型。DNA序列分析(n:72)使用ABI PRISM®3100遗传分析仪(Applied Biosystems, USA)进行,并通过BLAST分析进行分型。结果:样本(n: 77)的中位病毒载量为7 log10拷贝/mL (IQR: 4.5-7.4 log10拷贝/mL)。高病毒载量组(腺病毒DNA≥6 Log 10拷贝/mL)的临床表现评分明显高于低病毒载量组(腺病毒DNA)
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引用次数: 0
The effect of preemptive use of plerixafor on stem cell mobilization in patients with lymphoma and multiple myeloma 普立沙福对淋巴瘤和多发性骨髓瘤患者干细胞动员的影响
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244684
A. Uysal, M. Erkurt, Irfan Kuru, E. Kaya, İ. Berber, A. Sarici, S. Biçim, Ahmet Kaya, Emine Hidayet
ABSTRACT Objective: The aim of this study is to investigate the effect of the preemptive use of plerixafor in patients with lymphoma and multiple myeloma which was administered as a preemptive single dose to the patients who were determined to have a CD34+ cell count of
【摘要】目的:本研究的目的是探讨在淋巴瘤和多发性骨髓瘤患者中预先使用普利沙福的效果,该患者被确定为CD34+细胞计数
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引用次数: 0
Effect of angiotensin receptor-neprilysin inhibitor treatment on erectile dysfunction in heart failure with a reduced ejection fraction 血管紧张素受体-奈普利素抑制剂治疗心力衰竭伴射血分数降低患者勃起功能障碍的影响
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244456
S. Sert, E. Karabay, B. Gungor, O. Yildirimturk
Objective: Erectile dysfunction (ED) is a common condition in patients with heart failure (HF), which impairs quality of life. Our study aimed to compare those patients, who received traditional treatment with a diagnosis of HF and those who received angiotensin receptor-neprilysin inhibitor (ARNI) treatment in addition to the current treatment, in terms of ED at the end of 6 months. Patients and Methods: The study was planned as a single-center, prospective study. The study included 200 patients with heart failure. The patients’ demographic, clinical, and echocardiographic characteristics were recorded, and an international ED scoring questionnaire was applied. The participants in the study were divided into two groups: those who received ARNI treatment and those who did not. After 6 months, the ED questionnaire was applied to the patients again and the groups were compared. Results: The median age of the patients was 53 (years). The median ejection fraction (EF) value was calculated to be 30% and no significant difference was found between the groups (p: 0.122). It was found that N-terminal pro-brain natriuretic peptide (NT-pro- BNP) levels measured at the end of the 6th month were significantly lower in patients who had received ARNI treatment than in those who had not (respectively, 245 pg/ml, 200 pg/ml; p: 0.003). In the analysis performed to detect the presence of ED, it was discovered that the ED score change was significantly higher in the group that had received 6 months of ARNI treatment (p: 0.031) compared to that in the group that had not (p: 0.031). When the ED sub-parameters were compared in terms of the 6-month change rate, it was found that the ARNI group had a significant increase in terms of ED and sexual satisfaction scores, but no significant difference was found in the other parameters (p: 0.001, p: 0.029). Conclusion: Erectile dysfunction is more common in patients with heart failure compared to the rest of society and impairs quality of life. In our study, it was determined that ED complaints decreased significantly in HF patients, who had received ARNI treatment for 6 months than in patients who had not.
目的:勃起功能障碍(ED)是心力衰竭(HF)患者的常见病,严重影响患者的生活质量。我们的研究旨在比较那些接受传统治疗并诊断为HF的患者和在目前治疗的基础上接受血管紧张素受体-奈泼利素抑制剂(ARNI)治疗的患者在6个月后的ED情况。患者和方法:本研究计划为单中心前瞻性研究。该研究包括200名心力衰竭患者。记录患者的人口学、临床和超声心动图特征,并采用国际ED评分问卷。研究参与者被分为两组:接受ARNI治疗的组和未接受ARNI治疗的组。6个月后,再次对患者进行ED问卷调查,并进行组间比较。结果:患者中位年龄53岁。计算射血分数(EF)中位值为30%,两组间无显著差异(p: 0.122)。研究发现,在第6个月结束时,接受ARNI治疗的患者的n端前脑利钠肽(NT-pro- BNP)水平显著低于未接受ARNI治疗的患者(分别为245 pg/ml、200 pg/ml;p: 0.003)。在检测ED存在的分析中,发现接受6个月ARNI治疗组的ED评分变化明显高于未接受ARNI治疗组(p: 0.031)。当ED子参数以6个月变化率进行比较时,发现ARNI组在ED和性满意度评分方面显著增加,但在其他参数方面无显著差异(p: 0.001, p: 0.029)。结论:与其他人群相比,心力衰竭患者勃起功能障碍更为常见,并影响生活质量。在我们的研究中,我们确定接受ARNI治疗6个月的HF患者ED主诉比未接受ARNI治疗的患者显著减少。
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引用次数: 1
Medical students’ knowledge of the disease, frequency of depression, anxiety, stress symptoms, and related factors in the COVID-19 pandemic: A web-based questionnaire 医学生对疾病的了解、新冠肺炎大流行中抑郁、焦虑、压力症状的频率和相关因素:基于网络的问卷调查
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244747
Esra Çınar Tanrıverdi, M. Bayraktar, Suat Sincan, K. Kaşali, Y. Çayır, Mine Sahingoz, Z. Ozkurt
Objective: In this study, it was aimed to determine the level of knowledge of medical students about coronavirus disease 2019 (COVID-19), to investigate the frequency of depression, anxiety, stress symptoms and related factors. Materials and Methods: The study is a cross-sectional study conducted with 904 volunteer medical students. Data were collected with an online questionnaire, including sociodemographic characteristics, knowledge about COVID-19, the Depression, Anxiety, and Stress Scale. Results: Mean age was 21.3±2.2 years, and 54% of them (n=488) were female. Fifty five percent (n=497) thought that their level of knowledge about COVID-19 was sufficient, and 94.6% (n=846) were concerned about the disruption of their education. Their knowledge level was found to be 15.09±2.43 points out of 23 points. The depression, anxiety and stress symptoms were found in 64.9%, 70.4% and 34.1% of participants, respectively. The risk of anxiety (OR=0.51, 95%CI=0.94, p=0.020) and depression (OR=0.95, 95%CI=1.15, p=0.025) were higher in women. Those with a high fear of transmitting the COVID-19 infection to their relatives had higher symptoms of depression, anxiety, and stress. (p
目的:了解医学生对2019冠状病毒病(新冠肺炎)的认知水平,了解其抑郁、焦虑、应激症状的发生频率及相关因素。材料和方法:这项研究是一项横断面研究,共有904名志愿医学生参加。通过在线问卷收集数据,包括社会人口学特征、新冠肺炎知识、抑郁、焦虑和压力量表。结果:平均年龄21.3±2.2岁,其中女性占54%(n=488)。55%(n=497)认为他们对新冠肺炎的了解水平足够,94.6%(n=846)担心他们的教育受到干扰。他们的知识水平在23分中为15.09±2.43分。抑郁、焦虑和压力症状分别占64.9%、70.4%和34.1%。女性焦虑(OR=0.51,95%CI=0.94,p=0.020)和抑郁(OR=0.95,95%CI=1.15,p=0.025)的风险更高。那些高度害怕将新冠肺炎感染传染给亲属的人有更高的抑郁、焦虑和压力症状。(p
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引用次数: 0
Are neighborhood characteristics associated with physical activity levels among school children? 社区特征与学龄儿童的体育活动水平有关吗?
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244381
Gülin Kaya, P. Ay, S. Hıdıroğlu
Objective: The objective of this study was to determine the prevalence of insufficient physical activity (IPA) and neighborhood characteristics associated with it, among school children. The impact of sociodemographic characteristics and ownership of electronic devices on physical activity (PA) were also evaluated. Materials and Methods: This was a cross-sectional study carried out among 5-7th grade students attending schools and their parents. IPA was defined as having moderate-vigorous activity for 0.05). Conclusion: The prevalence of IPA is alarmingly high among school children. The impact of neighborhood characteristics on PA might be obscured since both variables were measured subjectively. Devices related information/communication technologies increase IPA; we need to find novel ways to use these devices for PA promotion. There is also a need to increase structured PA opportunities.
目的:本研究的目的是确定在校儿童中身体活动不足(IPA)的患病率及其相关的社区特征。社会人口学特征和电子设备拥有量对身体活动(PA)的影响也进行了评估。材料与方法:本研究为横断面调查,调查对象为在校5-7年级学生及其家长。IPA定义为中度剧烈活动(0.05)。结论:IPA在学龄儿童中的患病率高得惊人。邻域特征对PA的影响可能会被模糊,因为这两个变量都是主观测量的。设备相关的信息/通信技术增加IPA;我们需要找到新的方法来使用这些设备进行PA推广。还需要增加结构化PA的机会。
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引用次数: 0
The effects of mean platelet volume and red cell distribution width on prognosis in patients with myelodysplastic syndrome 骨髓增生异常综合征患者血小板平均体积和红细胞分布宽度对预后的影响
IF 0.2 Q4 Medicine Pub Date : 2023-01-31 DOI: 10.5472/marumj.1244731
Ihsan Ayhan, Ş. Ertop
Objective: In this study, the relationship between changes in mean platelet volume (MPV) and erythrocyte distribution width (RDW) with hematological response and survival in patients with myelodysplastic syndrome was investigated. Patients and Methods: Between 1 January 2011 and 31 December 2018, patient characteristics and hemogram results were evaluated during the treatment process among 158 patients diagnosed with myelodysplastic syndrome. Results: The mean age of the patients who were included in the study was 71.53±12.6 years. The MPV percentage change in the 2-year follow-up of the patients with and without hematological response was significant, at 0.022±0.11 (2.2%) in those who responded and at 0.069±0.15 (6.9%) in those who did not (p=0.049). Throughout the same period, the degree of RDW changes in the patients who died was 13.23±22.97, the degree in those who survived was 2.86±21.42, and the difference between the two groups was statistically significant (p=0.006). Conclusion: In patients diagnosed with myelodysplastic syndrome, MPV and RDW values can be considered inexpensive and simple laboratory markers that can be used in follow-ups and promising tests to predict both treatment response and survival in the early period and change treatment modalities.
目的:本研究探讨骨髓增生异常综合征患者平均血小板体积(MPV)和红细胞分布宽度(RDW)变化与血液学反应和生存的关系。患者和方法:在2011年1月1日至2018年12月31日期间,对158例诊断为骨髓增生异常综合征的患者在治疗过程中的患者特征和血像结果进行了评估。结果:纳入研究的患者平均年龄为71.53±12.6岁。在2年随访中,有和无血液学反应的患者MPV百分比变化显著,有反应的患者为0.022±0.11(2.2%),无反应的患者为0.069±0.15 (6.9%)(p=0.049)。同期,死亡患者的RDW变化程度为13.23±22.97,存活患者的RDW变化程度为2.86±21.42,两组差异有统计学意义(p=0.006)。结论:在诊断为骨髓增生异常综合征的患者中,MPV和RDW值可以被认为是廉价和简单的实验室标志物,可用于随访和有希望的测试,以预测早期的治疗反应和生存,并改变治疗方式。
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引用次数: 0
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Marmara Medical Journal
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