Effect of Orthodontic Aligners on Periodontal Health in Patients With and Without Trisomy 21 Introduction: Patients with Down Syndrome (T21) have a higher susceptibility to periodontal disease due to dental anomalies and difficulties with oral hygiene, which promote plaque accumulation. These patients often require orthodontic treatment to correct malocclusions and skeletal issues, which can be challenging. Orthodontic aligners are an alternative to traditional braces, offering benefits such as better hygiene and comfort.
Objective: To assess the periodontal condition of patients with T21 during treatment with orthodontic aligners.
Material and Methods: The study included 30 patients (ages 11-35), divided into two groups: T21 (n=10, treated prospectively) and CONTROL (n=20, accessed retrospectively). Both groups used Invisalign™ aligners and had their periodontal condition assessed before treatment and after 60, 120, 180, and 365 days, using the Gingival Bleeding Index (GBI) and Plaque Index (PI). Statistical analysis was performed using the Shapiro-Wilk, Chi-Square, Fisher, Mann-Whitney, ANOVA, and independent t-tests (p<0.05).
Results: The T21 group showed a higher incidence of periodontal pockets at the start of the study (p=0.038) and consistently higher plaque indices at all follow-up periods (p<0.05). No significant difference in gingival bleeding was observed between the groups (p>0.05).
Conclusion: Orthodontic aligners are a viable option for patients with T21, as they facilitate oral hygiene and help reduce the risk of periodontal complications. The study emphasizes the importance of a multidisciplinary approach to optimize clinical outcomes and improve the quality of life for these patients.
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