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64 - Corrosion- related alterations in surface properties and roughness of orthodontic wires 正畸金属丝表面特性和粗糙度的腐蚀相关改变
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.068
Martin Adriazola , Marcelo Goiato , Fernanda Vicioni-Marques , VIctor Perinazzo Sachi , Livia Maria Alves Valentim , André Pinheiro de Magalhaes Bertoz

Abstract

The surface characteristics of orthodontic wires play a crucial role in their clinical performance, particularly when exposed to varying oral environments. This study aimed to investigate the surface free energy and surface roughness (SR) of metallic alloys under the influence of acid solutions.

Methods

The experiment involved the use of 270 rectangular wire samples measuring 0.019 × 0.025 in. These samples were sourced from three different commercial brands: Dentsply GAC, American Orthodontics, and Orthoclassic. This in vitro study categorized the samples into three groups based on the solutions employed: deionized water, citric acid, and phosphoric acid. Each group consisted of 90 samples, with 30 samples representing each type of alloy—stainless steel, nickel-titanium, and titanium molybdenum alloy (TMA). The wire segments were immersed in their respective solutions for 72 hours at a controlled temperature of 37 °C, with continuous orbital agitation at 130 rpm. After the immersion period, the study analyzed both surface free energy and SR. The mean values obtained were subjected to an analysis of variance at a significance level of 5%.

Results

All alloys displayed hydrophobic behavior, as indicated by interaction free energy values < 0. In acidic environments (phosphoric acid and citric acid), significant differences were observed among different brands and alloys, affecting surface energy and interaction free energy. Variations in SR among metallic alloys included steel with the lowest SR variations, followed by nickel-titanium and TMA. Notably, the TMA alloy stood out with significantly higher surface energy compared with that of the other alloys (P < 0.001).

Conclusions

In this study, all examined alloys demonstrated a hydrophobic nature, suggesting a limited attraction to water. Notably, TMA exhibited the least hydrophobic behavior among the alloys studied. However, when exposed to citric acid, TMA displayed the most substantial alterations in its surface properties. These results underscored the significance of accounting for the distinctive properties of each alloy and their responses to diverse challenges, such as exposure to acidic solutions, during the selection of orthodontic wires for orthodontic treatment.
摘要正畸金属丝的表面特性对其临床性能起着至关重要的作用,特别是当暴露在不同的口腔环境中时。研究了酸溶液对金属合金表面自由能和表面粗糙度的影响。方法实验采用270根尺寸为0.019 × 0.025 in的矩形钢丝试样。这些样品来自三个不同的商业品牌:Dentsply GAC, American Orthodontics和Orthoclassic。这项体外研究根据使用的溶液将样品分为三组:去离子水、柠檬酸和磷酸。每组由90个样品组成,其中30个样品代表每种合金-不锈钢,镍钛和钛钼合金(TMA)。在37 °C的控制温度下,将导线段浸泡在各自的溶液中72小时,以130 rpm的速度连续轨道搅拌。浸渍期结束后,研究对表面自由能和sr进行分析,所得平均值进行5%显著性水平的方差分析。结果所有合金均表现出疏水行为,由相互作用自由能值<; 0可知。在酸性环境(磷酸和柠檬酸)中,不同品牌和合金的表面能和相互作用自由能存在显著差异。金属合金中SR的变化包括钢,SR变化最小,其次是镍钛和TMA。值得注意的是,TMA合金的表面能明显高于其他合金(P < 0.001)。在这项研究中,所有被检测的合金都表现出疏水性,表明对水的吸引力有限。值得注意的是,在所研究的合金中,TMA表现出最不疏水的行为。然而,当暴露于柠檬酸时,TMA在其表面特性上表现出最显著的变化。这些结果强调了在选择用于正畸治疗的正畸金属丝时,考虑每种合金的独特特性及其对不同挑战(例如暴露于酸性溶液)的反应的重要性。
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引用次数: 0
59 - Comparison of U1-Sn and Lip E-lines with orthodontic standards u1sn线与Lip e线与正畸标准的比较
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.063
Clarimar Soto , Andrea Gonzalez-Carbonell , Lydia Lopez-Del Valle , Sona Rivas-Tumanyan
It has been shown that Puerto Ricans, both male and female, have prominent lips compared to Caucasians. In orthodontics, patients are evaluated using standards established based on Caucasian populations. Therefore, it would be ideal to establish a standard norm for lip soft tissue values based on Puerto Rican population values.

Aims

To examine and compare the Upper Lip-Esthetic line and Lower Lip-Esthetic line values in the lateral cephalometric radiographs of adult Puerto Ricans patients of the UPR-Graduate Orthodontics Clinic with cephalometric norms.

Methods

This is a Cross-sectional study of 34 orthodontic dental records and lateral cephalometric radiographs. The study was conducted by tracing pre-treatment lateral cephalometric radiograph in Dolphin Imaging Program of patients with normal inclination of maxillary incisors between 18-35 years old. We collected three variables: the axial inclination of the most labial maxillary incisor, the upper lip and the lower lip to a line from the nose’s tip to soft tissue pogonion called esthetic line. Selection criteria included patients with U1-Sn measurement within the normal value (102.9° ±5.5°) according to the ABO 2012 cephalometric analysis and lips at normal rest position in cephalometric radiograph. Ricketts’s soft tissue measurement values (in mm) were summarized in terms of means (standard deviations) and medians (interquartile ranges). The study group estimates were compared to the esthetic norms using one-sample t-test or one-sample median test (at alpha = 0.05). Sample size provided us with over 97% power to detect a 1 mm difference (with 1 mm SD) from the norm.

Results

Mean U1-Sn for females was 103.39 SD= 2.88 and for males 103.44 SD= 2.95. Mean Upper Lip-EL -1.32 SD= 2.01 for females and -2.51 SD=2.98 for males. Mean Lower Lip-EL was 1.81 SD=1.73 for females and 0.75 SD=3.63 for males. No statistical differences were found for gender and mean U1-Sn, Upper Lip-EL and Lower Lip-EL (p value 0.967, 0.18 and 0.29) respectively. Lips in the Puerto Rican sample studied are more procumbent than what cephalometric norms suggest.

Conclusion

Clinical and statistical differences were found for Upper Lip-EL and Lower Lip-EL measurements in the PR population compared to orthodontic standards.
研究表明,与高加索人相比,波多黎各人,无论是男性还是女性,都有突出的嘴唇。在正畸学中,患者的评估使用基于高加索人群建立的标准。因此,建立一个基于波多黎各人口价值的唇软组织价值标准规范将是理想的。目的研究和比较upr -研究生正畸诊所成年波多黎各患者侧位头片上唇-审美线和下唇-审美线的价值与头片标准。方法对34例正畸患者的牙齿记录和侧位头颅x线片进行横断面研究。本研究对18-35岁上颌门牙倾斜度正常的患者进行了海豚成像程序治疗前的侧位头颅x线片追踪。我们收集了三个变量:上颌切牙最上唇的轴向倾斜度,上唇和下唇从鼻尖到软组织的一条线称为审美线。选择标准为:根据ABO 2012头颅测量分析和头颅x线片上嘴唇处于正常休息位置,u1sn测量值在正常值(102.9°±5.5°)内。Ricketts的软组织测量值(单位为mm)以均数(标准差)和中位数(四分位间距)进行总结。使用单样本t检验或单样本中位数检验将研究组的估计值与审美规范进行比较(alpha = 0.05)。样本量为我们提供了超过97%的功率来检测与标准的1毫米差异(1毫米SD)。结果女性平均U1-Sn为103.39 SD= 2.88,男性为103.44 SD= 2.95。平均上唇- el女性为-1.32 SD= 2.01,男性为-2.51 SD=2.98。女性的平均下唇电位为1.81 SD=1.73,男性为0.75 SD=3.63。性别与平均U1-Sn、Upper Lip-EL、Lower Lip-EL差异无统计学意义(p值分别为0.967、0.18、0.29)。波多黎各研究样本的嘴唇比头测法显示的更平躺。结论PR人群的上唇和下唇的el测量值与正畸标准相比具有临床和统计学差异。
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引用次数: 0
61 - Correlation between condylar volume and skeletal pattern in cone beam computed tomography: A systematic review 锥形束计算机断层扫描中髁突体积与骨骼形态的相关性:一项系统综述
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.065
María Elisa Covarrubias Zabala , Lisa Armstrong-Olivares , Carolina Castillo-Bombardiere , Camila Godoy-Cortés , Macarena Urrutia-Dufeu , Hernán Palomino-Montenegro

Background

The association between condylar volume (CV) and different skeletal patterns has a significant clinical implication since condylar volume plays an important role in the long-term stability of orthodontic treatment outcomes.

Objective

To evaluate the correlation between CV measured in cone beam computed tomography (CBCT) and vertical or sagittal skeletal patterns, and to assess if there was a difference among the skeletal patterns.

Methods

This systematic review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and JBI guidelines for evidence synthesis. The review protocol was registered on PROSPERO database (CRD42025641964). An electronic search was performed in PubMed, Scopus, Web of Science, Bireme and Google Scholar without time restriction. The endpoint of the search period was January 17, 2025. The risk of bias was performed with modified Newcastle Ottawa scale for cross-sectional studies.

Results

A total of 12 studies were included in the review. 9/12 articles assessed the CV by sagittal skeletal pattern. 6/9 of them reported that, compared to skeletal Class I, the CV was higher in Class III, 2/9 of them reported that was lower in Class II and 3/9 of them reported no significant association between CV and sagittal skeletal pattern. Additionally, 8/12 articles assessed by vertical growth pattern. 4/8 reported that the CV was higher in hypodivergent, 3/8 reported that was lower in hyperdivergent individuals and 1/8 reported no significant correlation between CV and vertical growth pattern. We evaluated 9/12 studies as unsatisfactory, 2/12 as satisfactory and 1/12 as good.

Conclusion

Although a tendency towards the skeletal patterns is seen, there is insufficient evidence to infer that the condylar volume is significantly correlated among the different skeletal patterns. More high-quality evidence is needed to use the skeletal pattern as predictor of the condylar volume.
背景:由于髁突体积对正畸治疗结果的长期稳定性起着重要作用,因此髁突体积(CV)与不同骨骼形态之间的关系具有重要的临床意义。目的探讨锥束ct (cone beam computed tomography, CBCT)测量的CV值与垂直或矢状骨型的相关性,并评估不同骨型之间是否存在差异。方法本系统评价以系统评价和荟萃分析首选报告项目(PRISMA)声明和JBI证据综合指南为基础。审查方案已在PROSPERO数据库中注册(CRD42025641964)。在PubMed、Scopus、Web of Science、Bireme、谷歌Scholar等网站进行电子检索,没有时间限制。搜索期的终点是2025年1月17日。偏倚风险采用改进的纽卡斯尔渥太华量表进行横断面研究。结果共纳入12项研究。9/12篇文章通过矢状骨模式评估CV。其中6/9的研究报告,与骨骼I类相比,III类的CV较高,2/9的研究报告II类的CV较低,3/9的研究报告CV与矢状骨型之间无显著相关性。此外,8/12篇文章以垂直增长模式评估。4/8的人报告说低发散个体的CV较高,3/8的人报告说高发散个体的CV较低,1/8的人报告说CV与垂直生长模式之间没有显著的相关性。我们将9/12的研究评价为不满意,2/12为满意,1/12为良好。结论髁突体积在不同骨型间的相关性虽有趋同趋势,但尚不足以说明髁突体积在不同骨型间的相关性。需要更多高质量的证据来使用骨骼类型作为髁突体积的预测因子。
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引用次数: 0
30 - Assesing the reliability of artificial intelligence-based automatic digital model analysis compared to manual system 评估基于人工智能的自动数字模型分析与手动系统的可靠性
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.034
Zeynep Beyçe Karaman , Kaan Kahya , Can Arslan , Derya Çakan
<div><div>In orthodontic treatment planning, model analysis plays a crucial role in evaluating the patient's dental and skeletal structure. Measurements and analyses are essential for understanding the severity of malocclusion and developing individualized treatment plans to achieve functional and aesthetic alignment. The accuracy of these measurements directly impacts treatment outcomes and patient satisfaction. Technological advancements have significantly influenced orthodontic model analysis. Within these digital systems, measurements can be obtained through manual segmentation of STL files uploaded into a software. With the advent of artificial intelligence (AI), software now enables automatic segmentation, offering precise measurements for model analysis parameters. AI-based automatic digital model analysis represents a paradigm shift in orthodontics, utilizing advanced algorithms to analyze digital models with greater speed, efficiency, and consistency than traditional methods. These systems promise transformative improvements but also raise questions regarding their diagnostic accuracy and clinical utility. Evaluating the differences between digital and manual methods is essential to ensure the reliability and safety of patient care. This study evaluates the accuracy and reliability of AI-supported digital model analysis compared to auto-segmented digital (AD), manual digital (MD), and manual plaster (MP) methods. Parameters such as tooth segmentation, measurement accuracy, and analysis efficiency are assessed. There remains a significant gap in the literature regarding studies that compare digital systems in their own methods of analysis options. Most of the digital software systems include manual segmentation and automatic segmentation options. The majority of the studies tend to compare digital systems to conventional plaster models, focusing on the differences and similarities between the two techniques. However, there is a lack of comprehensive analysis investigating how various digital methods perform relative to one another, without incorporating or relying on comparisons to traditional plaster model techniques. This gap highlights the need for studies that focus solely on the intra-domain evaluation of digital systems, which could provide deeper insights into their precision and reliability under different diagnostic and operational conditions. Twenty-four individuals, comprising 8 males and 16 females (19.5± 6,05 years of age), with all permanent teeth and mild to moderate crowding were selected. Linear measurements were made with a digital caliper on the plaster models of the selected patients. The digital models were manually and automatically segmented and measured using a Software. Mesiodistal tooth dimensions, arch widths were measured, and Bolton analysis was performed. Repeated measurements and statistical analysis show that all methods give consistent results. Low standard deviations and narrow confidence intervals indica
在正畸治疗计划中,模型分析在评估患者牙齿和骨骼结构方面起着至关重要的作用。测量和分析对于了解错牙合的严重程度和制定个性化的治疗计划以实现功能和美学对齐是必不可少的。这些测量的准确性直接影响治疗结果和患者满意度。技术进步对正畸模型分析产生了重大影响。在这些数字系统中,可以通过手动分割上传到软件中的STL文件来获得测量值。随着人工智能(AI)的出现,软件现在可以自动分割,为模型分析参数提供精确的测量。基于人工智能的自动数字模型分析代表了正畸学的范式转变,利用先进的算法来分析数字模型,比传统方法具有更高的速度、效率和一致性。这些系统有望带来革命性的改进,但也提出了有关其诊断准确性和临床实用性的问题。评估数字和手动方法之间的差异对于确保患者护理的可靠性和安全性至关重要。与自动分割数字(AD)、手动数字(MD)和手动石膏(MP)方法相比,本研究评估了人工智能支持的数字模型分析的准确性和可靠性。对牙齿分割、测量精度和分析效率等参数进行了评估。在文献中,关于比较数字系统自己的分析选择方法的研究仍然存在显著的差距。大多数数字软件系统包括手动分割和自动分割选项。大多数研究倾向于将数字系统与传统的石膏模型进行比较,重点关注两种技术之间的异同。然而,缺乏全面的分析,调查各种数字方法相对于彼此的表现,而不纳入或依赖于传统石膏模型技术的比较。这一差距凸显了只关注数字系统域内评估的研究需求,这可以更深入地了解它们在不同诊断和操作条件下的精度和可靠性。选取24例,男8例,女16例,年龄19.5±6.05岁,均为恒牙,轻度至中度拥挤。用数字卡尺对所选患者的石膏模型进行线性测量。采用软件对数字模型进行手动和自动分割和测量。测量中远端牙尺寸、牙弓宽度,进行博尔顿分析。反复测量和统计分析表明,所有方法的结果一致。低标准偏差和窄置信区间表明每个系统是可靠的,但有些方法可能更精确。在检查前磨牙以外的牙齿大小时,两种方法的差异有统计学意义(p < 0.05)。AD和MD系统在足弓长度不足、博尔顿差异等参数上无统计学差异。(p> 0.05)。AD法和MD法测量结果一致。由于传统的加工步骤,MP方法显示出较高的误差概率。用深度学习增强数字方法可以进一步提高基于ai的AD精度,使其更接近MD方法。
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引用次数: 0
37 - Behavior of orthodontic elastic ligatures with variation in internal diameter in tensile tests 正畸弹性结扎在拉伸试验中随内径变化的行为
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.041
Glaucio Serra Guimarães
Orthodontic elastics are essential for tooth movement, since their stress-strain properties allow them to transform elastic potential energy into mechanical energy, producing tooth movement. These elastics are available in a wide variety of types on the dental market and have variations in their dimensions from the same commercial brand or different brands. The objective of this study was to evaluate how the variation in the internal diameter of orthodontic elastic ligatures of 4 different commercial brands influences their fixation capacity, using simulations of first-order-bends in tensile tests with progressive magnitudes. The study evaluated the relationship between the internal diameter of orthodontic elastics and the force generated in tensile tests. A total of 240 samples of the brands Uniden, Morelli, Orthosouce and Unitek were tested. Previously, their dimensions were measured under a light microscope and tested in simulations of first-order orthodontic bends, varying between tractions of 0.5 mm, 1.0 mm and 1.5 mm, in a universal testing machine. Subsequently, the relationship between the dissipated force and the dimension of the internal diameter was investigated. In force tests of 0.5 mm, the groups of Unitek, Morelli and Orthosource elastics were significantly stronger than the Uniden. In tractions of 1.0 mm and 1.5 mm, the Unitek elastic presented the greatest force, followed by the Morelli and Orthosource elastics, with no statistical differences between them, and lastly the group of Uniden elastics. When subjected to correlation tests, there was no statistical significance in any of the correlations. The study concluded that there is no significant influence of the internal diameter on the fixation effectiveness of orthodontic ligatures.
正畸弹性对牙齿运动至关重要,因为它们的应力应变特性使它们能够将弹性势能转化为机械能,从而产生牙齿运动。这些橡皮筋在牙科市场上有各种各样的类型,并且在同一商业品牌或不同品牌的尺寸上有变化。本研究的目的是评估4种不同商业品牌的正畸弹性结扎的内径变化如何影响其固定能力,采用模拟一阶弯曲的逐步强度拉伸试验。本研究评估了正畸弹性内径与拉伸试验产生的力之间的关系。共检测了240个品牌的样品,包括Uniden、Morelli、orthosource和Unitek。以前,它们的尺寸是在光学显微镜下测量的,并在一阶正畸弯曲的模拟中进行测试,在通用试验机中在0.5 mm, 1.0 mm和1.5 mm的牵引力之间变化。随后,研究了耗散力与内径尺寸的关系。在0.5 mm的受力测试中,Unitek、Morelli和Orthosource弹性组明显强于Uniden。在牵引力1.0 mm和1.5 mm时,Unitek弹力最大,Morelli和Orthosource弹力次之,两者之间无统计学差异,Uniden弹力组次之。经相关检验,各相关性均无统计学意义。本研究认为内径对正畸结扎线固定效果无明显影响。
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引用次数: 0
38 - Behind the clench: bruxism’s impact on physical and psychological performance 咬牙切齿的背后:磨牙症对身体和心理表现的影响
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.042
Abdulmajeed Okshah , Sunil Kumar Vaddamanu , Imran Khalid , Mohammad Zahir Kota , Samuel Ebele Udeabor , Fawaz Abdul Hamid Baig
Bruxism is characterized by involuntary clenching and grinding of the teeth which is increasingly observed in competitive athletes, often triggered by stress, high training loads, and performance anxiety. This systematic review and meta-analysis aimed to evaluate the prevalence of bruxism among athletes and assess its effects on physical and psychological performance metrics. Following PRISMA guidelines, databases including PubMed, Scopus, and Web of Science were searched up to October 2023. Eleven studies involving 1,900 athletes met inclusion criteria. Performance-related outcomes included strength, endurance, agility, reaction time, sleep quality, anxiety, and injury incidence. The pooled prevalence of bruxism among athletes was 38%, significantly higher than in the general population. Meta-analytic results indicated that bruxism was associated with reduced strength and endurance (p < 0.001), slower reaction time and impaired agility (p < 0.05), increased anxiety and poor sleep quality (p < 0.001), and a 2.5-fold higher risk of sports injury. Endurance athletes and those self-reporting bruxism showed the greatest impairments. These findings highlight bruxism as a hidden yet influential factor in athletic performance. Incorporating dental assessments, occlusal evaluations, and preventive strategies into sports medicine protocols may offer a novel pathway for optimizing athlete health and performance.
磨牙症的特点是不自觉的咬牙和磨牙,在竞技运动员中越来越多地观察到,通常是由压力、高训练负荷和表现焦虑引起的。本系统综述和荟萃分析旨在评估磨牙症在运动员中的患病率,并评估其对身体和心理表现指标的影响。按照PRISMA的指导方针,检索了截至2023年10月的PubMed、Scopus和Web of Science等数据库。涉及1900名运动员的11项研究符合纳入标准。与成绩相关的结果包括力量、耐力、敏捷性、反应时间、睡眠质量、焦虑和受伤发生率。磨牙症在运动员中的总患病率为38%,明显高于普通人群。荟萃分析结果显示,磨牙症与力量和耐力下降(p < 0.001)、反应时间减慢和敏捷性受损(p < 0.05)、焦虑增加和睡眠质量差(p < 0.001)以及运动损伤风险增加2.5倍有关。耐力运动员和那些自我报告有磨牙症的人表现出最大的损伤。这些发现强调了磨牙症是影响运动表现的一个隐藏因素。将牙齿评估、咬合评估和预防策略纳入运动医学协议可能为优化运动员的健康和表现提供新的途径。
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引用次数: 0
19 - Analysis of various parameters of electric current & its effect on expression of bone markers and Osteosarcoma bone cells 电流各参数分析及其对骨标志物和骨肉瘤骨细胞表达的影响
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.023
Ashish Agrawal , Neelam Mittal , Md Zeyaullah xx

Background

The exogenous application of direct current has been widely explored in tissue engineering and has promising applications in cardiac tissues, nerve tissues, and bone regeneration due to its piezoelectric properties. Research done as early as the 1980s has demonstrated the potential of direct electric current for stimulating bone cells, however, the influence of various parameters of electric current being applied remained poorly understood.

Objective

To study the qualitative and quantitative effect of exogenous electric current (square waveform with varying pulsed frequency and amount of current) on Saos2 cells, and its impact on osteoprotegerin (OPG) and receptor activator of nuclear factor kappa-light -chain-enhancer of activated beta cells (RANK-L).

Material and Methods

The experimental setup was divided into groups, A - 1-second pulsed frequency (SPF) and B - 10-SPF. Each experimental group was subdivided into 5 subgroups (A1-A5, B1-B5) based on the current levels (10 µA -30 µA). The reverse piezoelectricity was applied 24 hours a day for 3 days. Two µlt of media were collected at 1, 3, 5, 7, 12, 24, 48, and 72hrs. which, was subjected to an ELISA. The cells were subjected to histological examination after 72 hours. The experiments were run in triplicate. The data obtained were subjected to statistical analysis.

Results

OPG and RANK-L expression was maximum at 30 µA at 24 hours in group B and peak level of OPG was delayed in group A to 48 hours. Peak RANK-L expression for group A was seen after 24 hours at 25 µA. There is an increasing trend of OPG expression at 1, 5, 12, and 24 hrs. respectively. Qualitative histological analysis showed an increase in the number and size of Saos2 cells at 30 µA current level and 10-second pulsed frequency.

Conclusion

Bioelectric stimulation can modulate both OPG and RANK-L levels. Unique frequencies can be applied to bone cells to regulate, alter, and optimize the expression of OPG and RANK-L.
外源直流电在组织工程中的应用已经得到了广泛的探索,由于直流电的压电特性,在心脏组织、神经组织和骨再生等方面有着广阔的应用前景。早在20世纪80年代所做的研究就证明了直流电刺激骨细胞的潜力,然而,所应用的各种电流参数的影响仍然知之甚少。目的研究外源电流(不同脉冲频率和电流量的方波)对Saos2细胞的定性和定量影响,以及对活化β细胞的骨保护素(OPG)和核因子κ a-轻链增强剂受体激活剂(RANK-L)的影响。材料与方法实验装置分为A - 1秒脉冲频率(SPF)组和B - 10-SPF组。按电流水平(10µA ~ 30µA)将各组再分为a1 ~ a5、b1 ~ b5 5个亚组。每天24小时施加反向压电,连续3天。在1、3、5、7、12、24、48和72小时收集2µlt培养基。然后进行ELISA检测。72h后对细胞进行组织学检查。实验做了三个重复。对获得的数据进行了统计分析。结果B组OPG和RANK-L在30µA时24 h表达量最大,而A组OPG峰值水平延迟至48 h。在25µA作用24小时后,A组RANK-L表达达到峰值。OPG表达在1、5、12、24 h呈上升趋势。分别。定性组织学分析显示,在30µA电流和10秒脉冲频率下,Saos2细胞的数量和大小均有所增加。结论生物电刺激可调节OPG和RANK-L水平。独特的频率可以应用于骨细胞来调节、改变和优化OPG和RANK-L的表达。
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引用次数: 0
13 - A vertical analysis of incisor positioning in adolescent patients treated with fixed orthodontic appliances 13 -固定矫治器治疗青少年患者门牙定位的纵向分析
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.017
Joshua Wiggins , A Syed , JM Palomo , MG Hans

Introduction

Fixed appliances are thought of being extrusive by nature, but there is no evidence as to if wearing fixed appliances has a significant effect on the vertical position of maxillary and mandibular incisors. The aim of this study is to evaluate vertical skeletal and dental changes in incisor positioning among adolescents treated with fixed orthodontic appliances, utilizing the Case Western Reserve University (CWRU) Vertical Analysis.

Methods

A retrospective case-control design with 30 adolescents (ages 10–15) who completed comprehensive non-extraction orthodontic treatment with full fixed pre-torqued, pre-angulated appliances was included. Subjects receiving any adjunctive vertical control methods, such as TADs, bite turbos, functional appliances, orthopedic expansion, extractions (excluding third molars), or segmental mechanics, were excluded. Each subject was matched to an untreated control by age, sex, and initial dental classification from the Bolton-Brush Growth Study. Vertical incisor changes were quantified using the CWRU Vertical Analysis, which evaluates both skeletal and dental components of vertical correction. Initial and final CBCTs were used to construct lateral cephalograms, and all cephalometric tracings were performed by a single calibrated examiner to ensure consistency. Seven key landmarks were identified: anterior nasal spine (ANS), incisal tip and apex of the maxillary and mandibular central incisors, and the centers of resistance of both incisors. Vertical changes were calculated using six independent variables: maxillary skeletal change, mandibular skeletal change, bodily and tipping movements of both maxillary and mandibular incisors. These changes were then compared to the corresponding control group.

Results

Preliminary results show significant differences between treated and untreated samples, with intrusive movements in the treated sample. No significant differences were found between genders.

Conclusions

The use of fixed appliances have a significant effect on the vertical position of the anterior dentition.
固定矫治器被认为是挤压性的,但没有证据表明佩戴固定矫治器对上颌和下颌门牙的垂直位置有显著影响。本研究的目的是利用凯斯西储大学(CWRU)垂直分析,评估使用固定正畸矫治器治疗的青少年门牙定位的垂直骨骼和牙齿变化。方法采用回顾性病例-对照设计,选取30例10-15岁青少年,采用全固定预扭、预成角矫治器完成综合非拔牙正畸治疗。受试者接受任何辅助垂直控制方法,如TADs、咬合涡轮、功能矫形器、矫形扩展、拔牙(第三磨牙除外)或节段力学均被排除。根据年龄、性别和博尔顿牙刷生长研究的初始牙齿分类,每个受试者与未经治疗的对照组相匹配。使用CWRU垂直分析来量化垂直切牙的变化,该分析评估了垂直矫正的骨骼和牙齿成分。初始和最终cbct用于构建侧位脑电图,所有的头部测量追踪都由一个校准的审查员进行,以确保一致性。确定了7个关键标志:鼻前棘(ANS)、上颌和下颌中切牙的切尖和切尖以及两切牙的阻力中心。垂直变化计算使用六个独立变量:上颌骨骼变化,下颌骨骨骼变化,上颌和下颌骨的身体和倾斜运动。然后将这些变化与相应的对照组进行比较。结果初步结果显示,处理后的样品与未处理的样品存在显著差异,处理后的样品中存在侵入性运动。性别间无显著差异。结论固定矫治器的使用对前牙列的垂直位置有显著影响。
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引用次数: 0
77 - Diet-induced obesity and alveolar bne loss: insights form a murine model 饮食引起的肥胖和牙槽骨丢失:小鼠模型的见解
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.081
Mario Alejandro Ortiz Salazar , Daniela Botero , Carolina Pustovrh

Background

Childhood/adolescence are critical for craniofacial development. While genetics play a role in the obesity pandemic, sociocultural factors, especially nutrition, are key. High-fat, high-energy diets impact bone health, crucial for orthodontic treatment outcomes.

Objectives

This pilot study evaluated the effects of an obesogenic diet on alveolar bone and femur microarchitecture in growing male Wistar rats.

Methods

Twelve rats were divided into control (standard diet) and experimental (cafeteria diet) groups for eight weeks. Weight, size, abdominal circumference, and glucose levels were monitored. Micro-CT analysis assessed bone microarchitecture.

Results

experimental group showed significant weight gain, increased abdominal circumference, and elevated glucose. Alveolar bone microarchitecture differed significantly; trabecular thickness (Tb.Th) was greater in the experimental group (109.808 ± 8.201 µm vs 94.577 ± 12.943 µm). Femoral head bone showed no differences. No statistical changes were observed in BV/TV, Tb.Th and Tb.Sp of femur.

Conclusions

An obesogenic diet negatively impacts alveolar bone microarchitecture, potentially affecting craniofacial development and orthodontic treatment. Further research is needed to understand the mechanisms and long-term implications. Understanding this relationship is crucial for comprehensive orthodontic care
童年/青春期是颅面发育的关键时期。虽然遗传因素在肥胖流行中起作用,但社会文化因素,尤其是营养因素,是关键。高脂肪、高能量饮食影响骨骼健康,对正畸治疗结果至关重要。目的本初步研究评估致肥性饮食对生长中的雄性Wistar大鼠牙槽骨和股骨微结构的影响。方法将12只大鼠分为对照组(标准饮食)和试验组(自助饮食),饲养8周。监测体重、体型、腹围和血糖水平。显微ct分析评估骨微结构。结果实验组患者体重明显增加,腹围增大,血糖升高。牙槽骨微结构差异显著;实验组小梁厚度(Tb.Th)较大(109.808±8.201µm vs 94.577±12.943µm)。股骨头无明显差异。BV/TV、Tb未见统计学变化。Th和Tb。股骨的Sp。结论肥胖饮食对牙槽骨微结构有负面影响,可能影响颅面发育和正畸治疗。需要进一步的研究来了解其机制和长期影响。了解这种关系对于全面的正畸护理至关重要
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引用次数: 0
79 - Digital burnout and its impact on orthodontic health: An emerging occupational health concern 79 -数字职业倦怠及其对正畸健康的影响:一个新兴的职业健康问题
IF 3.2 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 DOI: 10.1016/j.ejwf.2025.07.083
Vesela Stoichkova Pencheva-Georgieva , Maria Titopoulou
Digital burnout, characterized by prolonged screen exposure, mental fatigue and reduced physical activity has emerged as a growing occupational health concern in the digital age. While its psychological and neurological effects are well documented, its influence on dental and orthodontic wellbeing remains underexplored. Our study highlights how chronic stress from digital overuse can exacerbate conditions such as bruxism,TMD and postural strain. Poor ergonomics and extended periods of screen time also contribute to forward head posture, which may influence occlusion and facial muscle tension. By drawing attention to the interplay between workplace digital stress and oral health, this research underscores the need for integrated prevention strategies that combine mental wellness programs with dental and postural care in modern work environments.
Aim: to study the connection between the digital burnout and the TMJ disorders in people, working on computers daily.
Material and methods: 283 patients (109 men,174 women) have filled in a questionary with 25 questions and have been clinically examined.Average age 35,14±12,63.
Results: 20,1% of the women had TMJ pain while yawning, chewing and shouting, while only 5,6% all the men declared TMJ pain (p<0,001). During the clinical examination by the same doctor using the method of palpating was found that 11,5% of the men and 26,8% of the women had TMJ pain (p<0,003).To the question “Are there any noises during opening/closing of the mouth?” 22,3% of the men and 39% of the women said yes (p<0,005).
Conclusion: More than 1/3 of the patients have TMJ pain. Men do not understand the problem that well as women and figure it out only during the clinical examination.Recognizing the oral-systemic connection in the context of digital overuse is vital for developing preventive and interdisciplinary approaches in both workplace health management and clinical dental practice, incorporating digital wellness strategies and routine dental screening.
数字倦怠的特征是长时间接触屏幕、精神疲劳和体力活动减少,已成为数字时代日益严重的职业健康问题。虽然它对心理和神经系统的影响有很好的记录,但它对牙齿和正畸健康的影响仍未得到充分探讨。我们的研究强调了过度使用电子产品所带来的慢性压力是如何加剧磨牙症、TMD和姿势紧张等疾病的。不良的人体工程学和长时间的屏幕时间也会导致头部向前,这可能会影响闭塞和面部肌肉紧张。通过关注工作场所数字压力与口腔健康之间的相互作用,该研究强调了在现代工作环境中将心理健康计划与牙科和姿势护理相结合的综合预防策略的必要性。目的:探讨日常电脑工作人群的数字倦怠与颞下颌关节障碍的关系。材料和方法:283例患者(男性109例,女性174例)填写了一份包含25个问题的问卷,并进行了临床检查。平均年龄35、14±12、63岁。结果:20.1%的女性在打哈欠、咀嚼和叫喊时有TMJ疼痛,而只有5.6%的男性有TMJ疼痛(p< 001)。在同一医生使用触诊法进行的临床检查中,发现11.5%的男性和26.8%的女性有TMJ疼痛(p< 003)。对于“开/闭嘴巴时有声音吗?”22.3%的男性和39%的女性回答是肯定的(p< 005)。结论:1/3以上患者有颞下颌关节疼痛。男人不像女人那样了解这个问题,只有在临床检查时才能弄清楚。在数字过度使用的背景下,认识到口腔系统的联系对于在工作场所健康管理和临床牙科实践中制定预防性和跨学科方法,将数字健康战略和常规牙科筛查结合起来至关重要。
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引用次数: 0
期刊
Journal of the World Federation of Orthodontists
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