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Do Educated Women Have More Sexual Satisfaction? A Systematic Review Study 受过教育的女性性满意度更高吗?系统回顾研究
IF 0.4 Pub Date : 2022-12-07 DOI: 10.34172/cjmb.2023.03
F. Bayat, G. Ozgoli, Z. Mahmoodi, M. Nasiri
Objectives: Educational status affects all aspects of life, including sex life. Regarding the relationship between women’s sexual satisfaction and their education level, contradictory results have been obtained so far. This systematic review aimed to summarize the existing knowledge in this area. Methods: In this study, three electronic databases, including PubMed, Scopus, and Web of Science were searched for all the related articles published from 1 January, 2000 to 28 June, 2022. The MeSH keywords including "educational status", "education", and "sexual satisfaction" were combined with Boolean operators of AND and OR. There were no geographical constraints in this study. Inclusion criteria were all observational articles evaluating the relationship between the educational status of heterosexual, nonpregnant, and non-sick women with sexual satisfaction. The quality of articles was assessed by the Newcastle-Ottawa scale (NOS) and the data were analyzed qualitatively. Result: Out of a total of 4984 retrieved articles, nine studies with a sample size of 10488 women were included in this systematic review (2003-2021). In subjects with sexual dysfunction and mental health problems, as well as those affected by economic pressure, sexual satisfaction was predicted by the mentioned factors and not by the education level. Generally, in the studies where it was possible to compare the participants with all levels of education (illiterate to academic) and there was no sexual dysfunction, mental health problems, and economic pressure, women’s level of education was the predictor of their sexual satisfaction. Conclusions: According to our results, education was the most effective predictor of women’s sexual satisfaction in stable conditions without sexual dysfunction. Education can improve women’s educability, knowledge, and attitudes towards sexual issues, thereby increasing their sexual satisfaction. However, for a more definite conclusion, high-quality and larger studies are needed to measure the relationship between sexual satisfaction and women’s education.
目标:教育状况影响生活的方方面面,包括性生活。关于妇女的性满意度与其受教育程度之间的关系,迄今为止取得了相互矛盾的结果。本系统综述旨在总结这一领域的现有知识。方法:在本研究中,检索PubMed、Scopus和Web of Science三个电子数据库中2000年1月1日至2022年6月28日发表的所有相关文章。MeSH关键字包括“教育状况”、“教育程度”和“性满意度”与and和OR的布尔运算符相结合。这项研究没有地域限制。纳入标准均为观察性文章,评估异性恋、非怀孕和非患病女性的教育状况与性满意度之间的关系。文章的质量通过纽卡斯尔-渥太华量表(NOS)进行评估,并对数据进行定性分析。结果:在总共4984篇检索到的文章中,9项研究的样本量为10488名女性,被纳入本系统综述(2003-2021)。对于有性功能障碍和心理健康问题的受试者,以及那些受经济压力影响的人,性满意度是由上述因素预测的,而不是由教育水平预测的。一般来说,在可以将参与者与所有教育水平(文盲到学术水平)进行比较的研究中,没有性功能障碍、心理健康问题和经济压力,女性的教育水平是她们性满意度的预测因素。结论:根据我们的研究结果,在没有性功能障碍的稳定条件下,教育是女性性满意度的最有效预测因素。教育可以提高妇女的受教育能力、知识和对性问题的态度,从而提高她们的性满意度。然而,要想得出更明确的结论,还需要进行高质量、更大规模的研究来衡量性满意度与女性教育之间的关系。
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引用次数: 1
Ultrasonographic and Radiographic Evaluation of Zeolite/Collagen Nanocomposite Scaffolds Compared With Nanohydroxyapatite on Experimental Bone Defect Healing in Rabbit Femur 沸石/胶原纳米复合支架与纳米羟基磷灰石在兔股骨实验性骨缺损修复中的超声及影像学评价
IF 0.4 Pub Date : 2022-12-05 DOI: 10.34172/cjmb.2023.08
Negar Javadian, A. Veshkini, A. Jahandideh, A. Akbarzadeh, A. Asghari
Objectives: The use of a biomaterial scaffold can improve the healing process of bone defects. Using radiologic and ultrasonographic methods, this study aimed to evaluate the effects of zeolite/collagen nanocomposite and nanohydroxyapatite (nHA) bone scaffolds on the healing process of bone defect in rabbit femur. Materials and Methods: Twenty-eight mature male New Zealand white rabbits were classified into four equal groups (n=7 in each). In the first group, the defect was made, and the wound was closed with no treatment; in the second group, the nHA was implanted into the defect; in the third group, the nanocomposite of zeolite/collagen was implanted; and in the fourth group, the defect was filled using autograft. Radiologic (Sedecal Veterinary X-Ray System, Model No. A6544-2) and ultrasonographic (Mindray Z5 Veterinary Ultrasound Scanner) examinations were done on days 0, 15, 30, 45, and 60 postoperatively. Results: There were no healing effects on days 0 and 7 in any of the studied groups in the radiologic examination. The highest and lowest healing effects were related to treatment with zeolite/collagen nanocomposite and control group on day 60 after operation, respectively. There was no angiogenesis on day 0 in any group in the ultrasonographic examination. The highest and lowest levels of angiogenesis were related to rabbits treated with zeolite/collagen nanocomposite and the control group on day 30 after operation, respectively. Also, bone filling and angiogenesis in rabbits treated with zeolite/collagen nanocomposite were higher than other groups. Conclusions: Zeolite/collagen nanocomposite scaffolds bear a crucial capability in the reconstruction of bone defects and can be used in bone fractures.
目的:应用生物材料支架改善骨缺损的愈合过程。本研究采用影像学和超声影像学方法,探讨沸石/胶原纳米复合材料和纳米羟基磷灰石(nHA)骨支架对兔股骨骨缺损愈合过程的影响。材料与方法:雄性成年新西兰大白兔28只,随机分为4组,每组7只。第一组创面缺损,不做任何处理,直接闭合创面;第二组将nHA植入缺损;第三组植入沸石/胶原纳米复合材料;在第四组中,用自体移植物填充缺损。放射学专用兽医x光系统,型号:术后第0、15、30、45、60天分别行A6544-2)和超声检查(迈瑞Z5兽用超声扫描仪)。结果:两组患者放射学检查0、7 d均无愈合效果。沸石/胶原纳米复合材料组和对照组在术后第60天愈合效果最高,对照组愈合效果最低。超声检查各组第0天均未见血管新生。沸石/胶原纳米复合材料组和对照组血管新生水平分别在术后第30天达到最高和最低。沸石/胶原纳米复合材料处理家兔的骨填充和血管生成能力均高于其他各组。结论:沸石/胶原纳米复合支架具有重要的骨缺损重建能力,可用于骨折修复。
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引用次数: 0
Effect of Muscle Fatigue on the Upper Trapezius Muscle With and Without Myofascial Trigger Points in Students With Neck Pain: A Randomized Controlled Clinical Trial 肌肉疲劳对颈痛学生上斜方肌有无肌筋膜触发点的影响:一项随机对照临床试验
IF 0.4 Pub Date : 2022-11-03 DOI: 10.34172/cjmb.2023.06
Roya Mehdikhani, G. Olyaei, M. Hadian, Saeed Talebian Moghadam, S. Azadeh
Objectives: The purpose of this work was to explore cervical position sense and electromyographic (EMG) responses of cervical muscles during head repositioning movements in students with and without upper trapezius muscle trigger points. Materials and Methods: Forty-six right-handed men and women subjects without upper extremity disorders participated in this study. The maximal voluntary contraction (MVC) was measured three time before the fatigue test. A force gauge was used to measure force while recording with a monitor. Measurement was initiated with a MVC force before and after fatigue pain and head positioning were measured. When the protocol was accomplished, the subjects showed signs of exhaustion; however, they were not subjectively evaluated for fatigue. As the protocol aimed at assessing muscle fatigue, a force level of 80% MVC was induced. Results: These findings support the argument that the precision of the neck position sense can be reduced by the fatigue of the neck muscle. Fatigue impaired balance in the trapezius muscles. After removing vision this resulted in an increased center of pressure excursions on a force platform. Motor control did not change significantly in this study. Conclusions: Fatigue had a more significant effect on cervical kinematics in the healthy subjects, probably due to the fact that altered neck motor control in volunteers implied that these individuals were not completely able to make up for fatigue of the neck muscle. Significant pain and head positioning changes were identified following fatigue applied to the pre-determined myofascial trigger points, but the changes were insignificant in the sham control group.
目的:本工作的目的是探索有和没有上斜方肌触发点的学生在头部重新定位运动中颈部位置感和颈部肌肉的肌电图(EMG)反应。材料和方法:46名无上肢障碍的右撇子男性和女性受试者参与了这项研究。疲劳试验前三次测量最大自主收缩(MVC)。在用监视器进行记录时,使用测力仪测量力。在测量疲劳疼痛和头部定位之前和之后,用MVC力开始测量。当方案完成时,受试者表现出疲惫的迹象;然而,他们并没有主观地评估疲劳。作为旨在评估肌肉疲劳的方案,诱导了80%MVC的力水平。结果:这些发现支持了这样一种论点,即颈部肌肉的疲劳会降低颈部位置感的准确性。疲劳损害了斜方肌的平衡。在去除视觉后,这导致力平台上的压力偏移中心增加。在这项研究中,运动控制没有显著变化。结论:疲劳对健康受试者的颈部运动学有更显著的影响,可能是因为志愿者颈部运动控制的改变意味着这些人无法完全弥补颈部肌肉的疲劳。疲劳作用于预先确定的肌筋膜触发点后,发现明显的疼痛和头部位置变化,但假对照组的变化不显著。
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引用次数: 0
Evaluating Walnut-Fig Syrup as an Innovative Herbal Medicine for Functional Constipation in the Elderly: A Randomized Controlled Clinical Trial 核桃果糖浆作为一种治疗老年功能性便秘的创新草药的评价:一项随机对照临床试验
IF 0.4 Pub Date : 2022-10-07 DOI: 10.34172/cjmb.2022.32
Saeed Joudikhajeh, B. Sepehri, Robab Mehdizadeh Esfanjani, H. Rezaeizadeh, Yunes Ranjbar, Mostafa Araj-khodaei
Objectives: Functional constipation (FC), or chronic idiopathic constipation, is one of the most common chronic disorders with no specific cause. Although FC is not associated with the progress of severe disease or additional mortality, it significantly decreases the patients’ quality of life. While several medications are available to treat constipation, there is no adequate treatment response in most cases. Herbal remedies are one of the most widely used options for FC. Materials and Methods: In this double-blind controlled trial, all patients, researchers, and analysts were unaware of the ingredients contained in the drugs, as well as the assigned groups. We recruited a total of 90 elderly patients diagnosed with FC according to the Rome IV diagnostic criteria for irritable bowel syndrome (IBS). Patients were divided into two equal groups (n=45 in each) receiving fig-walnut syrup and lactulose syrup. Then, CBC-FBS-TSH-CR-NA-K-CA tests were taken from all patients, and the developed syrups (walnut-fig or lactulose) were prescribed to patients (15 cc half an hour before bedtime). Results: While 43 (95.6%) patients responded to treatment in the intervention group, 41 (91.1%) patients responded to treatment in the conventional treatment group. There was no statistically significant difference between the two groups in terms of response to treatment (P = 0.677). Conclusions: The results showed that the oral syrups developed in this study improved FC in the elderly and had no side effects.
目的:功能性便秘(FC),或称慢性特发性便秘,是最常见的无特定病因的慢性疾病之一。尽管FC与严重疾病的进展或额外的死亡率无关,但它会显著降低患者的生活质量。虽然有几种药物可以治疗便秘,但在大多数情况下没有足够的治疗反应。草药疗法是FC最广泛使用的选择之一。材料和方法:在这项双盲对照试验中,所有患者、研究人员和分析人员都不知道药物中所含的成分以及指定的组。我们共招募了90名根据罗马IV肠易激综合征(IBS)诊断标准诊断为FC的老年患者。患者被分为两组(每组n=45),分别服用无花果核桃糖浆和乳果糖糖浆。然后,对所有患者进行CBC-FBS-TSH-CR-NA-K-CA测试,并给患者开具开发的糖浆(核桃无花果或乳果糖)(睡前半小时15毫升)。结果:干预组有43例(95.6%)患者对治疗有反应,而常规治疗组有41例(91.1%)患者对处理有反应。两组对治疗的反应没有统计学意义(P=0.677)。结论:本研究开发的口服糖浆改善了老年人的FC,没有副作用。
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引用次数: 0
Evaluating the Relationship Between Structural Determinants of Health and Quality of Sexual Life in Women: A Systematic Review 评价女性健康结构决定因素与性生活质量之间的关系:一项系统综述
IF 0.4 Pub Date : 2022-09-14 DOI: 10.34172/cjmb.2022.30
Marzieh Bagherinia, M. Dolatian, Zoherh Mahmoodi, G. Ozgoli, H. Alavi Majd
Objectives: Quality of sexual life can be influenced by cultural and social contexts. This study aimed to investigate the relationship between structural determinants of health (such as education, income level, job, culture, and ethnicity) and quality of sexual life in women. Methods: In this systematic review, we searched six databases, including Web of Science, Scopus, ProQuest, PubMed/Medline (NLM), Cochrane, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) to obtain all the related observational studies (cross-sectional, cohort, and case-control). Results: Nine studies met the inclusion criteria. Based on the Newcastle-Ottawa Scale (NOS), the risk of bias in most of the included studies was fair. According to the results, the relationship between education level and quality of sexual life among women was significant in four studies. Also, in one study, job and income level were significantly correlated with women’s quality of sexual life. Conclusions: Based on the results, structural determinants of health, including education, job, and income level were significantly related with women’s quality of sexual life.
目的:性生活的质量会受到文化和社会背景的影响。这项研究旨在调查妇女健康的结构性决定因素(如教育、收入水平、工作、文化和种族)与性生活质量之间的关系。方法:在本系统综述中,我们检索了Web of Science、Scopus、ProQuest、PubMed/Medline (NLM)、Cochrane、Embase和Cochrane Central Register of Controlled Trials (Central)等6个数据库,获取所有相关的观察性研究(横断面、队列和病例对照)。结果:9项研究符合纳入标准。根据纽卡斯尔-渥太华量表(NOS),大多数纳入研究的偏倚风险是公平的。结果显示,在四项研究中,受教育程度与女性性生活质量的关系显著。此外,在一项研究中,工作和收入水平与女性的性生活质量显著相关。结论:基于研究结果,健康的结构性决定因素,包括教育、工作和收入水平与女性性生活质量显著相关。
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引用次数: 0
Protective Effect of Hydroalcoholic Extracts of Galega officinalis and Cornus mas on Spermatogenesis and Oxidative Stress Associated With Diabetes in the Testes of Adult Rats: An Experimental Study 厚朴和山茱萸水醇提取物对成年大鼠睾丸精子生成和糖尿病相关氧化应激的保护作用的实验研究
IF 0.4 Pub Date : 2022-09-14 DOI: 10.34172/cjmb.2023.07
E. Sanati, Iraj Posti, H. Gilanpour, S. Hesaraki
Objectives: In this research, we evaluated the protective effect of hydroalcoholic extracts of Galega officinalis and Cornus mas on spermatogenesis and oxidative stress associated with diabetes in the testes of adult rats. Materials and Methods: In this experimental study, a total of 64 adult male Wistar rats were divided into eight equal groups (n=8 in each) as follows: (1) control group, (2) diabetic control group, (3) diabetic group receiving Galega extract daily at a dose of 50 mg/kg, (4) healthy group receiving Galega extract daily at a dose of 50 mg/kg for 14 days, (5) diabetic group receiving Cornus mas extract daily at a dose of 100 mg/kg, (6) healthy group receiving Cornus mas extract daily, (7) diabetic group receiving Cornus mas and Galega daily, and (8) healthy group receiving Galega and Cornus mas extract daily. Diabetes was induced by single intraperitoneal injection of streptozotocin (50 mg/kg). At the end of treatment period, all animals were anesthetized and blood samples were taken to measure the serum levels of insulin, glucose, and oxidative stress markers. Finally, the testicles and epididymis were removed and sperm parameters were assessed. Results: Galega and Cornus mas extract significantly reduced the oxidative stress, sperm parameters, glucose, and insulin plasma levels (P=0.001). Furthermore, the malondialdehyde (MDA) level was increased in diabetic rats. The activity of superoxide dismutase (SOD) and catalase (CAT) enzymes decreased in testicular tissue (P=0.001). Administering Galega and Cornus mas extract significantly improved these parameters (P<0.05). Conclusions: Our results confirmed the antioxidant effect of administering Galega extract and Cornus mas extract on improving the sperm parameters and testicular oxidative damage caused by diabetes.
目的:本研究探讨了鸭尾草和山茱萸水醇提取物对成年大鼠睾丸中糖尿病相关的精子发生和氧化应激的保护作用。材料与方法:本实验选用成年雄性Wistar大鼠64只,随机分为8组,每组8只。(1)对照组,(2)糖尿病对照组,(3)糖尿病组每日给予斗嘴豆提取物50 mg/kg剂量,(4)健康组每日给予斗嘴豆提取物50 mg/kg剂量,连用14 d,(5)糖尿病组每日给予斗嘴豆提取物100 mg/kg剂量,(6)健康组每日给予斗嘴豆提取物,(7)糖尿病组每日给予斗嘴豆和斗嘴豆提取物,(8)健康组每日给予斗嘴豆和斗嘴豆提取物。单次腹腔注射链脲佐菌素(50 mg/kg)诱导糖尿病。在治疗期结束时,所有动物都被麻醉,并采血测量血清胰岛素、葡萄糖和氧化应激标志物的水平。最后,切除睾丸和附睾,评估精子参数。结果:Galega和山茱萸提取物显著降低了氧化应激、精子参数、血糖和胰岛素血浆水平(P=0.001)。此外,糖尿病大鼠丙二醛(MDA)水平升高。睾丸组织超氧化物歧化酶(SOD)和过氧化氢酶(CAT)活性降低(P=0.001)。给药鸭尾豆和山茱萸提取物显著提高了这些指标(P<0.05)。结论:本研究证实了鸭舌豆提取物和山茱萸提取物对糖尿病大鼠精子参数和睾丸氧化损伤的抗氧化作用。
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引用次数: 0
Development and Validation of an Electronic Scale for Sexual Violence Experiences in Iranian Women 伊朗妇女性暴力经历电子量表的开发与验证
IF 0.4 Pub Date : 2022-09-14 DOI: 10.34172/cjmb.2023.05
Shahrzad Sanjari, Mohammad Reza Mohammidi Soleimani, A. Keramat
Objectives: According to the evidence, 35% of women have experienced sexual violence worldwide. This study aimed to develop and validate an electronic scale for sexual violence experiences (SVE) in Iranian women. Materials and Methods: In this mixed-method study, we conducted an item pool by reviewing the existing sexual violence scales in the literature and sent the items to the expert team for initial consensus. Then, we measured the validity and reliability of the developed scale. The samples included 808 women (age range: 15-45 years) in Kerman province from October to December 2020. Results: The final scale consisted of 43 items. Face validity was achieved by applying the views of the target community. The content validity results were acceptable. The correlation coefficient between the Sexual Experience Questionnaire (SEQ) and the Domestic Violence Questionnaire (DVQ) with the SVE was 0.68 and 0.51, respectively. Exploratory factor analysis (EFA) (χ2 =27973.72, df=903, and P=0.001) identified eight factors. The results also showed good reliability (Cronbach’s alpha=0.9, Pearson’s correlation r=0.9, P=0.001). Conclusions: Since the SVE had good validity and reliability, the scale can be regarded as a suitable tool for measuring sexual violence among Iranian women.
目标:根据证据,全世界35%的妇女经历过性暴力。本研究旨在开发和验证伊朗妇女性暴力经历电子量表。材料和方法:在这项混合方法研究中,我们通过审查文献中现有的性暴力量表来进行项目库,并将项目发送给专家团队以获得初步共识。然后,我们测量了开发的量表的有效性和可靠性。样本包括2020年10月至12月克尔曼省的808名女性(年龄范围:15-45岁)。结果:最终量表由43个项目组成。人脸有效性是通过应用目标群体的观点来实现的。内容有效性结果可接受。性经验问卷(SEQ)和家庭暴力问卷(DVQ)与SVE的相关系数分别为0.68和0.51。探索性因素分析(EFA)(χ2=27973.72,df=903,P=0.001)确定了8个因素。结果也显示出良好的可靠性(Cronbach’s alpha=0.9,Pearson’s correlation r=0.9,P=0.001)。结论:由于SVE具有良好的有效性和可靠性,该量表可以作为衡量伊朗妇女性暴力的合适工具。
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引用次数: 4
Association Between Nutritional Status and Quality of Life in Patients With Allergic Rhinitis 过敏性鼻炎患者营养状况与生活质量的关系
IF 0.4 Pub Date : 2022-09-14 DOI: 10.34172/cjmb.2022.35
Elham Bagherinia, Marzieh Bagherinia, Firoozeh Khamoushi, A. Davoodi, Seyed Hamidreza Mortazavi
Objectives: Allergic rhinitis (AR) is a heterogeneous disorder with immune pathophysiology affecting quality of life (QOL) and productivity at work or education. This study aimed to evaluate the association between macro- and micro-nutrient intakes with QOL in AR patients. Materials and Methods: Using convenience sampling method, this cross-sectional study included 60 AR patients in the age range of 15-60 years referred to the Allergy Clinic of Mohammad Kermanshashi hospital, Kermanshash, Iran from March to December 2018. Data including body composition, QOL, and nutritional status were collected. Independent t test, chi-square, and Pearson correlation were used for data analysis. Results: According to the results of Spearman test, while cholesterol intake level was directly associated with low QOL (P = 0.049, r=0.283), dietary zinc intake had a negative correlation with low QOL (P = 0.045, r=-0.262). However, there were no significant associations between other macro- and micro-nutrient intakes and QOL in patients. Conclusions: In this study, higher intake of cholesterol, unlike zinc, had a negative effect on QOL in AR patients.
目的:过敏性鼻炎(AR)是一种异质性疾病,其免疫病理生理学影响生活质量(QOL)和工作或教育生产力。本研究旨在评估AR患者的宏微量营养素摄入量与生活质量之间的关系。材料和方法:本横断面研究采用方便抽样法,纳入了2018年3月至12月在伊朗克尔曼沙什Mohammad Kermanshashi医院过敏诊所转诊的60名年龄在15-60岁之间的AR患者。收集包括身体成分、生活质量和营养状况在内的数据。数据分析采用独立t检验、卡方检验和皮尔逊相关。结果:Spearman检验结果显示,胆固醇摄入水平与低生活质量直接相关(P=0.049,r=0.283),膳食锌摄入与低生活水平呈负相关(P=0.045,r=-0.262),但其他宏微量营养素摄入与患者生活质量无显着相关性。结论:在本研究中,与锌不同,高胆固醇摄入对AR患者的生活质量有负面影响。
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引用次数: 0
Actual Preoperative Fasting Time; A Report From Guilan Academic Hospitals: A Cross-sectional Study 术前实际禁食时间;桂兰学术医院报告:横断面研究
IF 0.4 Pub Date : 2022-09-09 DOI: 10.34172/cjmb.2023.19
Bahram Naderi Nabi, Soudabeh Haddadi, F. Farzi, S. Ghazanfar Tehran, Gelareh Biazar, Yasmin Chaibakhsh, Zahra Atrkarroushan, M. Habibi, Seyed Sepehr Khatami
Objectives: Traditional guidelines for preoperative fasting (POF) time lead to several complications in surgery patients. However, not enough attention has been paid to the issue. This aimed of this study was to investigate the management of fasting times in Guilan academic hospitals. Materials and Methods: In this descriptive cross-sectional study, individuals from five academic referral centers enrolled the survey and questionnaires including demographic characteristics, fasting hours for liquids and solids, POF recommenders, and patient’s knowledge regarding the definition of clear liquids were completed. Results: A total of 390 individuals candidate for elective surgeries enrolled in the study, the mean age of our cases were 46.61 years. The average POF time for solids and liquids was 11.43 and 9.70 hours, respectively. 95.38% of the participants did not know a correct definition of clear liquids, which was not related to their level of education (P=0.314). A positive association was observed between age and POF times for liquids and American Society of Anesthesiologists Classification for both solids (P=0.010) and liquids (P=0.0001). Conclusions: It was found that the real POF time in our hospitals was significantly longer than the modern guidelines, and needs to be corrected.
目的:传统的术前禁食(POF)时间指南会导致手术患者出现一些并发症。然而,这一问题没有得到足够的重视。本研究旨在调查桂兰学院医院禁食时间的管理情况。材料和方法:在这项描述性横断面研究中,来自五个学术转诊中心的个人参加了调查,并完成了问卷调查,包括人口统计学特征、液体和固体的禁食时间、POF推荐人以及患者对清澈液体定义的知识。结果:共有390名择期手术候选人参加了这项研究,我们病例的平均年龄为46.61岁。固体和液体的平均POF时间分别为11.43和9.70小时。95.38%的参与者不知道澄清液体的正确定义,这与他们的教育水平无关(P=0.314)。年龄与液体POF时间和美国麻醉师协会固体和液体分类呈正相关(P=0.010)。结论:我们发现我们医院的实际POF时间明显长于现代指南,需要纠正。
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引用次数: 0
Evaluation of Testosterone, Blood Antioxidants, and Histopathological Changes Following Chemical Castration With Calcium Chloride in Rats 大鼠氯化钙化学阉割后睾酮、血液抗氧化剂和组织病理学变化的评估
IF 0.4 Pub Date : 2022-09-09 DOI: 10.34172/cjmb.2022.34
M. Hami, A. Veshkini, A. Jahandideh, Siamak Mashhadi Rafiee, P. Mortazavi
Objectives: Castration is one of the most common methods of contraception in animals. This method can prevent animals from contracting various diseases, such as testicular tumors, and prevent the overgrowth of animal populations. Materials and Methods: In this experiment, 10 adult and clinically healthy male Wistar rats weighing approximately 250-200 g were divided into two equal groups of control and treatment (n=5 in each). In the control group, normal saline and in the treatment group, 20% calcium chloride was injected into the testicular tissue. Blood samples were taken at the beginning and end of the experiment (day 21) and the superoxide dismutase (SOD), glutathione peroxidase (GPx), and testosterone levels were measured. Then, the tissue samples of testis were evaluated on days 7, 14, and 21. Results: On day 21, SOD and GPx enzymes significantly increased in the treatment group compared to day zero (P=0.01). However, calcium chloride injection reduced the mean testosterone levels on day 21 compared to day zero (P=0.06). Meanwhile, the mean number of sperms in the right testis of treated mice significantly decreased (P=0.03). Seminiferous tubule necrosis significantly increased on day 7, neutrophil infiltration significantly increased on days 7 and 14, and calcification significantly increased on days 7 and 21 (P<0.01). Conclusions: Although chemical sterilization using 20% calcium chloride can lead to testicular degeneration, it is not a recommended method because it does not reduce testosterone and activates oxidative stress biomarkers. However, the negative effects might be eliminated in future studies using some substances such as tannic acid.
目的:阉割是动物最常见的避孕方法之一。这种方法可以防止动物感染各种疾病,如睾丸肿瘤,并防止动物种群过度生长。材料和方法:在本实验中,将10只体重约250-200g的成年和临床健康雄性Wistar大鼠分为两组,每组5只,每组相等。对照组和治疗组分别向睾丸组织注射生理盐水和20%氯化钙。在实验开始和结束时(第21天)采集血样,测量超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GPx)和睾酮水平。然后,在第7、14和21天对睾丸的组织样本进行评估。结果:第21天,治疗组SOD和GPx酶较第0天显著升高(P=0.01),而氯化钙注射液使第21天的平均睾酮水平较第0天降低(P=0.06),小鼠右睾丸平均精子数显著下降(P=0.03),第7天半精小管坏死显著增加,第7、14天中性粒细胞浸润显著增加,钙化在第7天和第21天显著增加(P<0.01)。结论:尽管使用20%氯化钙进行化学灭菌会导致睾丸变性,但这不是一种推荐的方法,因为它不会降低睾酮并激活氧化应激生物标志物。然而,在未来的研究中,使用一些物质(如单宁酸)可能会消除负面影响。
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引用次数: 1
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Crescent Journal of Medical and Biological Sciences
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