Pharmacologic management of hypertension includes many major classes of drugs. Angiotensin-Converting Enzyme Inhibitors (ACEI) is one of them. In fact, ACEI is considered the first choice in many recent guidelines3,4. ACEI have many indications in addition to blood pressure lowering. For example, many studies had found consistent beneficial effects in postmyocardial infarction, heart failure, and chronic kidney disease patients5. This led to the widespread use of these agents.
{"title":"High Incidence of Cough among Users of Angiotensin-Converting Enzyme Inhibitors","authors":"J. Nasser, Khadija Al Aradi, K. S. Ebrahim","doi":"10.12816/0047558","DOIUrl":"https://doi.org/10.12816/0047558","url":null,"abstract":"Pharmacologic management of hypertension includes many major classes of drugs. Angiotensin-Converting Enzyme Inhibitors (ACEI) is one of them. In fact, ACEI is considered the first choice in many recent guidelines3,4. ACEI have many indications in addition to blood pressure lowering. For example, many studies had found consistent beneficial effects in postmyocardial infarction, heart failure, and chronic kidney disease patients5. This led to the widespread use of these agents.","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44109686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
118 Sickle cell disease (SCD) is one of the most common inherited hemolytic anemias affecting millions of people worldwide with a high prevalence in sub-Saharan Africa, accounting for approximately 80% of the cases globally and in the Middle East1,2. The prevalence in Bahrain has been estimated at 1.3% with a high phenotypic variation due to its association with coinherited α and β thalassemia alleles3,4.
{"title":"A Rare Concurrence of Hodgkin’s Lymphoma, Sickle Cell Disease and Diabetes Mellitus","authors":"Zainab A Toorani, S. Sridhar, W. Roque","doi":"10.12816/0047565","DOIUrl":"https://doi.org/10.12816/0047565","url":null,"abstract":"118 Sickle cell disease (SCD) is one of the most common inherited hemolytic anemias affecting millions of people worldwide with a high prevalence in sub-Saharan Africa, accounting for approximately 80% of the cases globally and in the Middle East1,2. The prevalence in Bahrain has been estimated at 1.3% with a high phenotypic variation due to its association with coinherited α and β thalassemia alleles3,4.","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47028379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Affected children usually presented with hypotonia, poor sucking, and failure to thrive during infancy, followed by polyphagia, obesity, and intellectual disability during childhood, and hypogonadism, short stature, and behavioral disturbance during adolescence. In addition, characteristic facial features, such as almond eyes, narrow forehead, thin upper lips, and small hands and feet would be seen2. The prevalence ranges from 1/25,000 to 1/10,000 live born children3.
{"title":"Can Prader-Willi Syndrome Present with Autism ?","authors":"Dalal Burshaid, A. Al-Jawad, N. Ahmed","doi":"10.12816/0047569","DOIUrl":"https://doi.org/10.12816/0047569","url":null,"abstract":"Affected children usually presented with hypotonia, poor sucking, and failure to thrive during infancy, followed by polyphagia, obesity, and intellectual disability during childhood, and hypogonadism, short stature, and behavioral disturbance during adolescence. In addition, characteristic facial features, such as almond eyes, narrow forehead, thin upper lips, and small hands and feet would be seen2. The prevalence ranges from 1/25,000 to 1/10,000 live born children3.","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44213099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
121 Uterine torsion is defined as the rotation of the uterus on its long axis greater than 45 degrees. Uterine torsion usually ranges from 45 degrees to 180 degrees, but up to 720 degrees have been reported1. Only 212 cases were reported in the literature until 19922. In two-thirds of cases, the uterus was dextrorotated and the other one-third it was levorotared3. The degree of torsion described varied from 60-720 degrees.
{"title":"Intrauterine Fetal Death in a Torted Gravid Uterus","authors":"N. Abdulaal, Sally Aldeeb, S. Anwar","doi":"10.12816/0047566","DOIUrl":"https://doi.org/10.12816/0047566","url":null,"abstract":"121 Uterine torsion is defined as the rotation of the uterus on its long axis greater than 45 degrees. Uterine torsion usually ranges from 45 degrees to 180 degrees, but up to 720 degrees have been reported1. Only 212 cases were reported in the literature until 19922. In two-thirds of cases, the uterus was dextrorotated and the other one-third it was levorotared3. The degree of torsion described varied from 60-720 degrees.","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46161029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Future of the Radiation Therapy Treatments in Bahrain","authors":"I. Fotina","doi":"10.12816/0047553","DOIUrl":"https://doi.org/10.12816/0047553","url":null,"abstract":"","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44208951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends and Clinical Outcomes of Registered TB Cases 1999 - 2011 : Is There a Significant Change in Extrapulmonary Pattern ?","authors":"B. Al-Ghamdi","doi":"10.12816/0047556","DOIUrl":"https://doi.org/10.12816/0047556","url":null,"abstract":"","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49594550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The pathophysiology of gestational thrombocytopenia is unknown. It is thought to be related to hemodilution, increased platelet consumption, and increased platelet aggregation because of increased levels of thromboxane A2. It is a diagnosis of exclusion, occurring in the mid-second and third trimester8. Women are typically asymptomatic. Platelet count is typically greater than 70,000/μL and is resolved postnatally. Thrombocytopenia among Pregnant Women
{"title":"Thrombocytopenia among Pregnant Women","authors":"N. Khallouf, N. Dayoub","doi":"10.12816/0047557","DOIUrl":"https://doi.org/10.12816/0047557","url":null,"abstract":"The pathophysiology of gestational thrombocytopenia is unknown. It is thought to be related to hemodilution, increased platelet consumption, and increased platelet aggregation because of increased levels of thromboxane A2. It is a diagnosis of exclusion, occurring in the mid-second and third trimester8. Women are typically asymptomatic. Platelet count is typically greater than 70,000/μL and is resolved postnatally. Thrombocytopenia among Pregnant Women","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47073780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gomez-Lopez-Hernandez Syndrome : A Rare Neurocutaneous Syndrome","authors":"A. Ali, A. Hajeri","doi":"10.12816/0047564","DOIUrl":"https://doi.org/10.12816/0047564","url":null,"abstract":"","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43137297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alkali burns are more severe than acidic burns because of their rapid penetrating effect through the cornea. Alkali agents cause saponification of fatty acids in the cell membrane with subsequent destruction of mucopolysaccharides at the same time; they enhance the collagenolysis process causing tissue necrosis and perforation. On the other hand, acidic agents precipitate tissue protein in which they create a barrier to further ocular penetration; an exception to this is hydrofluoric acid1-3. Common causative agents in chemical eye injuries include1: acids such as sulfuric acid, bleach and refrigerants, hydrochloric acid, acetic acid and hydrofluoric acid; alkali, such as ammonia, lye; lime, plaster and mortar, potassium hydroxide and magnesium hydroxide.
{"title":"Management of Alkali Eye Injury","authors":"Abdulla Almoosa, Muhammad Atif Mian","doi":"10.12816/0047563","DOIUrl":"https://doi.org/10.12816/0047563","url":null,"abstract":"Alkali burns are more severe than acidic burns because of their rapid penetrating effect through the cornea. Alkali agents cause saponification of fatty acids in the cell membrane with subsequent destruction of mucopolysaccharides at the same time; they enhance the collagenolysis process causing tissue necrosis and perforation. On the other hand, acidic agents precipitate tissue protein in which they create a barrier to further ocular penetration; an exception to this is hydrofluoric acid1-3. Common causative agents in chemical eye injuries include1: acids such as sulfuric acid, bleach and refrigerants, hydrochloric acid, acetic acid and hydrofluoric acid; alkali, such as ammonia, lye; lime, plaster and mortar, potassium hydroxide and magnesium hydroxide.","PeriodicalId":43814,"journal":{"name":"Bahrain Medical Bulletin","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46540974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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