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Clinical skills in therapeutic plasmapheresis in intensive care: A scoping review 重症监护中血浆置换治疗的临床技能:范围综述
IF 1.1 Q3 NURSING Pub Date : 2025-06-19 DOI: 10.1016/j.enfi.2025.500556
Pedro Ramos-Figueiras MSc , Maria Pinto-Marques PhD , Margarida Palma-Goes PhD , Henrique Oliveira PhD

Background

Therapeutic plasmapheresis is a procedure primarily focused on modulating the immune system by removing specific antibodies and albumin-bound toxins implicated in the development of serious pathologies, and it is being used more frequently in intensive care units. In this therapeutic intervention, nursing teams mostly use the knowledge and skills acquired through experience with continuous dialysis techniques. However, the procedure is complex and advanced, requiring the development of specific skills.

Aim

To map the nursing interventions that facilitate the development of specific clinical skills for therapeutic plasmapheresis.

Methodology

The methodology adopted was based on a scoping review. The Population, Concept, Context methodology was used to formulate the review question and to select the articles. The search was carried out in the scientific databases CINAHL, MEDLINE, COCHRANE, Virtual Health Library and international journals specializing in apheresis techniques knowledge, with the inclusion criteria “nursing care”, “peer-reviewed articles” and the exclusion criteria “no full text” and “date less than 2017” applied. In addition, the most recent international guidelines on therapeutic plasmapheresis were included.

Results

A total of 11 articles were identified, of which 7 are textual evidence articles, based on expert opinions and database searches, and 4 are quantitative studies; in addition to 5 guidelines related to the subject under analysis. These reflect the importance of developing skills in therapeutic plasmapheresis, categorized into general, technical, management and communication domains. Nursing interventions are based on the principle of clinical reasoning, promoting evidence-based practice. The relevance of certifying these skills through training is also highlighted, emphasizing the need for structured programs for an adequate approach to highly complex therapeutic interventions.

Conclusion

Therapeutic plasmapheresis plays an essential role in intensive care settings, covering various clinical scenarios, which requires an individualized approach and careful consideration of the person's specific clinical condition.
治疗性血浆置换是一种主要侧重于通过去除与严重病理发展相关的特异性抗体和白蛋白结合毒素来调节免疫系统的手术,它在重症监护病房中使用得更频繁。在这种治疗干预中,护理团队主要使用通过持续透析技术获得的知识和技能。然而,这个过程是复杂和先进的,需要发展特定的技能。目的制定护理干预措施,促进治疗性血浆置换的特定临床技能的发展。方法采用的方法是基于范围审查。使用人口、概念、背景方法来制定审查问题和选择文章。检索科学数据库CINAHL、MEDLINE、COCHRANE、Virtual Health Library及国际采血技术知识专业期刊,纳入标准为“nursing care”、“同行评议文章”,排除标准为“无全文”和“日期小于2017”。此外,还包括最新的治疗性血浆置换国际指南。结果共鉴定出11篇论文,其中基于专家意见和数据库检索的文本证据文章7篇,定量研究4篇;除了与所分析的主题有关的5项准则之外。这反映了发展治疗性血浆分离技术的重要性,分为一般、技术、管理和交流领域。护理干预以临床推理原则为基础,促进循证实践。通过培训证明这些技能的相关性也得到了强调,强调了对高度复杂的治疗干预采取适当方法的结构化方案的必要性。结论治疗性血浆置换在重症监护环境中发挥着至关重要的作用,它涵盖了各种临床情况,需要个性化的方法并仔细考虑患者的具体临床情况。
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引用次数: 0
Monitorización de intervenciones enfermeras nocturnas en las unidades de cuidados críticos pediátricos españolas 监测西班牙儿科重症监护病房的夜间护理干预措施
IF 1.1 Q3 NURSING Pub Date : 2025-06-11 DOI: 10.1016/j.enfi.2025.500555
Alicia Gomez-Merino RN, MSc , Patricia Luna-Castaño PhD, RN, MSc , Marta Martín-Velasco RN , Natalia González-Martínez RN, MSc , Pedro Piqueras-Rodríguez RN, MSc , Irina Marcos-Blázquez RN, MSc , Sara Álvarez-Blanco RN , Lucía Gutiérrez-Horrillo RN, MSc , Elia Mas-Company RN , Enara Otero-Arbella RN , Elena Martín-Camacho RN, MSc , María Teresa Arias-Latorre RN, MSc , Sara Rodríguez-Flórez RN, MSc , María de los Ángeles Morán-Barrio RN , María Teresa Moreno-Casbas RN, PhD, FEAN, FAAN

Introduction

The hostile environment in paediatric intensive care units (PICU) favours sleep-wake biorhythm dysregulation. Sleep disorders have detrimental impact on the immune, neurological and cardiovascular systems, in addition to increasing morbidity and mortality rates. Sleep plays a crucial role in brain development, rendering paediatric patients particularly vulnerable to the adverse effects of sleep disorders due to their ongoing neurological growth. The factors that affect rest include, among others, noise, lighting, treatment, and nocturnal nursing interventions, although the evidence for the latter is still scarce.

Objective

To identify the nocturnal nursing interventions, following the NIC taxonomy, carried out in PICU.

Method

A multicentre, cross-sectional, descriptive study was performed using an ad hoc survey to identify nocturnal nursing interventions in the PICU. The collected variables were characteristics of the participating PICU and those derived from the nursing interventions. During the analysis, mean and standard deviation of quantitative variables, and frequency tables and percentages were generated for qualitative variables. The variables were operationalized and Student's t-test and ANOVA were calculated for comparison between variables.

Results

One hundred records were obtained, encompassing 5017 interventions, with the most repeated intervention being “vital signs monitoring”. The mean number of different interventions identified was 23 ± 7.66 and the mean frequency of these was 50.17 ± 19.28. There were significant differences between the hospital variable and the number and frequency of interventions performed (p < 0.001).

Discussion

We agreed with other studies in identifying “vital signs monitoring” as the most frequent intervention. “Improving sleep” was one of the most frequently reported, in contrast to other studies where interventions related to rest were not documented.

Conclusions

The most frequently performed interventions in the PICU were identified. In most of the registers some intervention on improving rest was identified, which could indicate the latent concern of the health care professionals for the sleep of the critical child.
儿科重症监护病房(PICU)的恶劣环境有利于睡眠-觉醒生物节律失调。睡眠障碍除了增加发病率和死亡率外,还对免疫、神经和心血管系统产生有害影响。睡眠在大脑发育中起着至关重要的作用,由于儿科患者的神经系统正在发育,因此他们特别容易受到睡眠障碍的不利影响。影响休息的因素包括噪音、照明、治疗和夜间护理干预,尽管后者的证据仍然很少。目的探讨重症监护病房夜间护理干预措施。方法采用一项多中心、横断面、描述性研究,通过特别调查确定PICU的夜间护理干预措施。收集的变量是参与PICU的特征和护理干预的特征。在分析过程中,生成定量变量的均值和标准差,以及定性变量的频率表和百分比。对变量进行操作化处理,并计算学生t检验和方差分析进行变量间比较。结果共获得100条记录,干预措施5017项,重复次数最多的是“生命体征监测”。不同干预的平均次数为23±7.66次,平均频率为50.17±19.28次。医院变量与进行干预的次数和频率之间存在显著差异(p <;0.001)。讨论我们同意其他研究将“生命体征监测”确定为最常见的干预措施。“改善睡眠”是最常被报道的研究之一,而在其他研究中,与休息相关的干预措施没有记录在案。结论确定了PICU中最常用的干预措施。在大多数的记录中都发现了一些改善休息的干预措施,这可能表明卫生保健专业人员对危重儿童的睡眠存在潜在的关注。
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引用次数: 0
Análisis de disponibilidad, formación y uso de ecografía por enfermeras en urgencias intra y extrahospitalarias. Una encuesta nacional 护士在医院内外急诊中的超声可用性、培训和使用情况分析。全国调查
IF 1.1 Q3 NURSING Pub Date : 2025-05-31 DOI: 10.1016/j.enfi.2025.500552
Sergio Yago-Rios RN. MsC , Raimunda Montejano-Lozoya RN, MsC, PhD , Llucia Valentín-Martín RN, MsC , Carmen Casal-Angulo RN, MsC, PhD , Brais Quintairos-Manso , Ángeles Rodríguez-Herrera RN, MsC, PhD , Vicente Isidro Manrique-Ortiz RN , Jorge Prieto-González RN. MsC , Juan Carlos Miranda-Domínguez RN. MsC , Àngela Soler-Sanchís RN, MsC , Pablo Sánchez-Ballesteros RN, MsC , Álvaro Solaz-García RN, MsC, PhD

Introduction

The use of ultrasound devices in emergency services has grown significantly, particularly point-of-care ultrasound (POCUS), which has enhanced patient management and treatment, reduced costs, and minimized radiation exposure. In nursing, POCUS has become an essential tool, especially for vascular access procedures. However, disparities in training and access to ultrasound equipment exist across emergency services in different regions of Spain. This study aims to explore these differences and their impact on clinical practice.

Methodology

A cross-sectional, descriptive, observational study was conducted, involving nurses from emergency services throughout Spain. Data were collected via an online survey validated through the Delphi method. The study received approval from the Ethics Committee.

Results

A total of 424 professionals from all regions except the Balearic Islands participated, representing 123 hospital emergency services, 15 prehospital services, and 20 primary care centers. Overall, 79% had access to ultrasound devices, with significant differences across service types (P<.01). Only 36% reported having access to a full range of probes. Notably, 63% of participants lacked formal ultrasound training. Variability in equipment availability and training differed significantly between regions (P<.05).

Discussion

The findings highlight substantial disparities in the availability of ultrasound devices and probes across different services and regions. Additionally, most nursing professionals lack ultrasound training. Compared to other European countries, availability in Spain is lower. The lack of training may stem from the absence of nationally accredited programs, leaving individual resources as the primary means of acquiring skills.

Conclusion

Significant inequalities exist in access to ultrasound equipment and training among emergency services and regions in Spain. Professional training in this field varies depending on the region studied.
超声设备在急诊服务中的使用已显著增加,特别是护理点超声(POCUS),它加强了患者的管理和治疗,降低了成本,并最大限度地减少了辐射暴露。在护理中,POCUS已成为必不可少的工具,特别是在血管通路手术中。然而,西班牙不同地区的急诊服务部门在培训和获得超声设备方面存在差异。本研究旨在探讨这些差异及其对临床实践的影响。方法进行了一项横断面、描述性、观察性研究,涉及西班牙各地急诊部门的护士。通过德尔菲法验证的在线调查收集数据。该研究获得了伦理委员会的批准。结果共有424名专业人员参加了调查,他们来自除巴利阿里群岛以外的所有地区,分别代表123家医院急诊服务机构、15家院前服务机构和20家初级保健中心。总体而言,79%的人可以使用超声设备,不同服务类型之间存在显著差异(P< 0.01)。只有36%的人表示能够接触到全方位的探针。值得注意的是,63%的参与者缺乏正规的超声训练。设备可用性和培训的可变性在地区之间存在显著差异(P< 0.05)。研究结果强调了超声设备和探头在不同服务和地区的可用性的巨大差异。此外,大多数护理专业人员缺乏超声培训。与其他欧洲国家相比,西班牙的可用性较低。培训的缺乏可能源于缺乏国家认可的项目,使个人资源成为获得技能的主要手段。结论西班牙不同急诊部门和地区在超声设备和培训的获取方面存在显著的不平等。这一领域的专业培训因所研究的地区而异。
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引用次数: 0
Impacto de la vacunación frente al COVID-19 en los costos hospitalarios en los enfermos ingresados en una unidad de cuidados intensivos durante la cuarta, quinta y sexta oleada de la pandemia 2019冠状病毒病疫苗对第四、第五和第六波大流行期间重症监护病房住院费用的影响
IF 1.1 Q3 NURSING Pub Date : 2025-05-22 DOI: 10.1016/j.enfi.2025.500551
Alejandro González-Castro MD, pHD , David Iglesias MD , Yhivian Peñasco MD, pHD , Carmen Huertas Marín MD , Elena Cuenca-Fito MD , Trinidad Dierssen-Soto MD, pHD , Reinhard Wallmann MD , Raquel Ferrero-Franco RN , Camilo González MD , Juan Carlos Rodríguez-Borregán MD

Background and objective

COVID-19 vaccination may alter the course of severe disease and influence hospital discharge costs. This study compares hospital discharge costs among ICU-admitted COVID-19 patients based on vaccination status, adjusted for All Patient Refined Diagnosis Related Groups (APR-DRG) and severity.

Patients and methods

A retrospective study (March 2020-March 2022) was conducted in an ICU, categorizing patients into three groups: unvaccinated, fully vaccinated, and partially vaccinated. Full vaccination included all required doses and boosters per the vaccination schedule. Disease severity was classified as mild, moderate, severe, and critical. Direct hospital costs, including ICU stay, medical procedures, medications, and life support, were analyzed using data from Order SAN/35/2017, adjusted for inflation. Chi-square and Kruskal-Wallis tests with Bonferroni correction were used for comparisons.

Results

A total of 456 patients were included: 262 (57%) unvaccinated, 32 (7%) partially vaccinated, and 162 (35%) fully vaccinated. Median costs were:
  • Unvaccinated: €10,653 (IQR: €6,160-€18,274)
  • Partially vaccinated: €17,360 (IQR: €5,061-€26,085)
  • Fully vaccinated: €10,653 (IQR: €6,160-€26,085)
Cost differences were not statistically significant (P=.28). Critical severity patients had the highest costs, while mild cases had the lowest (P<.05). No significant cost differences were found within each severity level or in APR-DRG relative weight (P=.38).

Conclusions

No significant differences in hospital discharge costs by APR-DRG were found based on vaccination status. However, vaccination may reduce disease severity and the need for intensive resources, with potential economic and clinical implications for future research.
背景与目的covid -19疫苗接种可能改变重症病程,影响出院费用。本研究比较了icu收治的COVID-19患者基于疫苗接种状况的出院费用,并根据所有患者精细诊断相关组(APR-DRG)和严重程度进行了调整。患者和方法回顾性研究(2020年3月- 2022年3月)在ICU进行,将患者分为三组:未接种疫苗、完全接种疫苗和部分接种疫苗。全面疫苗接种包括按疫苗接种计划接种所需的所有剂量和加强剂。疾病严重程度分为轻度、中度、重度和危重。直接住院费用,包括ICU住院、医疗程序、药物和生命支持,使用SAN/35/2017号命令的数据进行分析,并根据通货膨胀进行调整。比较采用卡方检验和Kruskal-Wallis检验,并采用Bonferroni校正。结果共纳入456例患者:未接种疫苗262例(57%),部分接种疫苗32例(7%),完全接种疫苗162例(35%)。中位数成本为:•未接种疫苗:10,653欧元(IQR:€6,160-€18,274)•部分接种疫苗:€17,360 (IQR:€5,061-€26,085)•完全接种疫苗:€10,653 (IQR:€6,160-€26,085)成本差异无统计学意义(P= 0.28)。危重患者的费用最高,轻症患者的费用最低(p < 0.05)。在每个严重程度级别或APR-DRG相对权重中没有发现显著的成本差异(P= 0.38)。结论不同疫苗接种情况下APR-DRG的出院费用无显著差异。然而,疫苗接种可能降低疾病严重程度和对密集资源的需求,对未来的研究具有潜在的经济和临床意义。
{"title":"Impacto de la vacunación frente al COVID-19 en los costos hospitalarios en los enfermos ingresados en una unidad de cuidados intensivos durante la cuarta, quinta y sexta oleada de la pandemia","authors":"Alejandro González-Castro MD, pHD ,&nbsp;David Iglesias MD ,&nbsp;Yhivian Peñasco MD, pHD ,&nbsp;Carmen Huertas Marín MD ,&nbsp;Elena Cuenca-Fito MD ,&nbsp;Trinidad Dierssen-Soto MD, pHD ,&nbsp;Reinhard Wallmann MD ,&nbsp;Raquel Ferrero-Franco RN ,&nbsp;Camilo González MD ,&nbsp;Juan Carlos Rodríguez-Borregán MD","doi":"10.1016/j.enfi.2025.500551","DOIUrl":"10.1016/j.enfi.2025.500551","url":null,"abstract":"<div><h3>Background and objective</h3><div>COVID-19 vaccination may alter the course of severe disease and influence hospital discharge costs. This study compares hospital discharge costs among ICU-admitted COVID-19 patients based on vaccination status, adjusted for All Patient Refined Diagnosis Related Groups (APR-DRG) and severity.</div></div><div><h3>Patients and methods</h3><div>A retrospective study (March 2020-March 2022) was conducted in an ICU, categorizing patients into three groups: unvaccinated, fully vaccinated, and partially vaccinated. Full vaccination included all required doses and boosters per the vaccination schedule. Disease severity was classified as mild, moderate, severe, and critical. Direct hospital costs, including ICU stay, medical procedures, medications, and life support, were analyzed using data from Order SAN/35/2017, adjusted for inflation. Chi-square and Kruskal-Wallis tests with Bonferroni correction were used for comparisons.</div></div><div><h3>Results</h3><div>A total of 456 patients were included: 262 (57%) unvaccinated, 32 (7%) partially vaccinated, and 162 (35%) fully vaccinated. Median costs were:<ul><li><span>•</span><span><div>Unvaccinated: €10,653 (IQR: €6,160-€18,274)</div></span></li><li><span>•</span><span><div>Partially vaccinated: €17,360 (IQR: €5,061-€26,085)</div></span></li><li><span>•</span><span><div>Fully vaccinated: €10,653 (IQR: €6,160-€26,085)</div></span></li></ul></div><div>Cost differences were not statistically significant (<em>P</em>=.28). Critical severity patients had the highest costs, while mild cases had the lowest (<em>P</em>&lt;.05). No significant cost differences were found within each severity level or in APR-DRG relative weight (<em>P</em>=.38).</div></div><div><h3>Conclusions</h3><div>No significant differences in hospital discharge costs by APR-DRG were found based on vaccination status. However, vaccination may reduce disease severity and the need for intensive resources, with potential economic and clinical implications for future research.</div></div>","PeriodicalId":43993,"journal":{"name":"Enfermeria Intensiva","volume":"36 3","pages":"Article 500551"},"PeriodicalIF":1.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infarto de miocardio alérgico por picadura de abeja 蜜蜂叮咬引起的过敏性心肌梗死
IF 1.1 Q3 NURSING Pub Date : 2025-05-03 DOI: 10.1016/j.enfi.2025.500550
Beatriz Gómez-Martín RN, MSN

Introduction and case presentation

Kounis Syndrome is the association of acute coronary syndrome (ACS) in the context of a hypersensitivity reaction whose prevalence is difficult to identify and its etiology is multifactorial, which makes its early detection difficult. The unusual case of a woman who suffers an acute myocardial infarction (AMI) with cardiorespiratory arrest (CPA) secondary to the accidental sting of a bee is presented. The objective is, regarding the case, to define the nursing interventions and the individualized care plan.

Assessment

Based on Virginia Henderson's care model, the assessment of the nursing care process was carried out.

Diagnosis and planning

According to the NANDA taxonomy, the nursing diagnoses and potential problems that developed during their stay in the unit were described. Standardized language was used establishing NOC objectives and NIC interventions.

Discussion and conclusions

The combination of both pathologies in a single entity can make the management of this syndrome in the acute phase difficult, which modifies the conventional scenario of a CPA. Defining a standardized care plan is a fundamental axis to provide optimal quality of care based on evidence in the absence of standardized algorithms in the literature.
简介和病例介绍库尼斯综合征与急性冠状动脉综合征(ACS)有关,是一种过敏反应,其患病率难以确定,病因是多因素的,这使得其难以早期发现。不寻常的情况下,一个妇女谁遭受急性心肌梗死(AMI)与心肺骤停(CPA)继发的意外蜇伤的蜜蜂提出。目的是,针对该病例,确定护理干预措施和个性化护理计划。评估基于Virginia Henderson的护理模型,对护理过程进行评估。诊断和计划根据NANDA分类,描述了他们在住院期间的护理诊断和潜在问题。采用标准化语言建立NOC目标和NIC干预措施。讨论与结论两种病理的合并在急性期会使该综合征的管理变得困难,这改变了传统的CPA方案。定义标准化的护理计划是在文献中缺乏标准化算法的情况下基于证据提供最佳护理质量的基本轴。
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引用次数: 0
Incidencia de complicaciones en pacientes sometidos a terapia de reemplazo renal continuo anticoagulada con citrato sódico 柠檬酸钠连续抗凝肾替代治疗患者的并发症发生率
IF 1.1 Q3 NURSING Pub Date : 2025-04-19 DOI: 10.1016/j.enfi.2025.500544
Juan Carlos Muñoz-Camargo RN, MSc, PhD, Inmaculada Vázquez-Rodríguez-Barbero RN, Alicia Muñoz-Torrero-Peña RN, Amadeo Puebla-Martín RN

Introduction

Acute kidney injury (AKI) is a frequent complication in Intensive Care Unit (ICU) patients with high morbidity and mortality.

Objective

To analyze the incidence of mechanical and metabolic adverse events associated with continuous renal replacement therapy using sodium citrate as a regional anticoagulant.

Material and methods

Observational, descriptive and prospective study performed in a polyvalent ICU during three years. Patients with AKI treated with renal replacement therapy and sodium citrate (Prismocitrate 18/0 mmol/L [0.5%]) were included. Patients with liver failure, active bleeding, severe thrombocytopenia, ICU stay of less than 24 hours or treated with other anticoagulants were excluded. Demographic variables, severity index (APACHE II), vasoactive drug use, adverse events, and catheter characteristics were recorded. Anticoagulation efficacy was assessed with filter duration. Statistical analysis was performed with SPSS v.28.0, with p< 0.05 as the significance level. The study was approved by the ethics committee and informed consent was obtained from the patients or their relatives.

Results

We studied 100 patients, 62% men, with a mean age of 63 ± 14.5 years. The main causes of AKI were septic shock, hemorrhagic shock and Covid-19. The median ICU stay was 16 days (RIC 8-43), with intra-ICU mortality of 48%. Therapy lasted a median of 60.5 hours (RIC 38-107). Only one patient presented bleeding, and in 26% the filter coagulated. There were no cases of citrate toxicity. Electrolyte complications included hypocalcemia (45%), hypokalemia (41%), hyponatremia (36%) and metabolic acidosis (30%).

Conclusions

Mechanical and metabolic complications are common in continuous renal replacement therapies with sodium citrate. It is essential for ICU staff to be aware of their high prevalence in order to optimize clinical management.
急性肾损伤(AKI)是重症监护病房(ICU)患者的常见并发症,具有很高的发病率和死亡率。目的分析枸橼酸钠局部抗凝持续肾替代治疗中机械和代谢不良事件的发生率。材料和方法在多价ICU进行了为期三年的观察性、描述性和前瞻性研究。接受肾替代疗法和柠檬酸钠(Prismocitrate 18/0 mmol/L[0.5%])治疗的AKI患者纳入研究。排除肝功能衰竭、活动性出血、严重血小板减少、ICU住院时间小于24小时或使用其他抗凝药物的患者。记录人口统计学变量、严重程度指数(APACHE II)、血管活性药物使用、不良事件和导管特征。用过滤时间评价抗凝效果。采用SPSS v.28.0进行统计学分析,采用p<;0.05为显著性水平。本研究经伦理委员会批准,并获得患者或其亲属的知情同意。结果100例患者,男性62%,平均年龄63±14.5岁。发生AKI的主要原因是感染性休克、失血性休克和新冠肺炎。中位ICU住院时间为16天(RIC 8-43), ICU内死亡率为48%。治疗持续时间中位数为60.5小时(RIC 38-107)。只有一名患者出现出血,26%的患者滤过物凝固。没有柠檬酸盐中毒的病例。电解质并发症包括低钙血症(45%)、低钾血症(41%)、低钠血症(36%)和代谢性酸中毒(30%)。结论枸橼酸钠持续肾替代治疗常见机械和代谢并发症。为了优化临床管理,ICU工作人员必须了解其高发率。
{"title":"Incidencia de complicaciones en pacientes sometidos a terapia de reemplazo renal continuo anticoagulada con citrato sódico","authors":"Juan Carlos Muñoz-Camargo RN, MSc, PhD,&nbsp;Inmaculada Vázquez-Rodríguez-Barbero RN,&nbsp;Alicia Muñoz-Torrero-Peña RN,&nbsp;Amadeo Puebla-Martín RN","doi":"10.1016/j.enfi.2025.500544","DOIUrl":"10.1016/j.enfi.2025.500544","url":null,"abstract":"<div><h3>Introduction</h3><div>Acute kidney injury (AKI) is a frequent complication in Intensive Care Unit (ICU) patients with high morbidity and mortality.</div></div><div><h3>Objective</h3><div>To analyze the incidence of mechanical and metabolic adverse events associated with continuous renal replacement therapy using sodium citrate as a regional anticoagulant.</div></div><div><h3>Material and methods</h3><div>Observational, descriptive and prospective study performed in a polyvalent ICU during three years. Patients with AKI treated with renal replacement therapy and sodium citrate (Prismocitrate 18/0 mmol/L [0.5%]) were included. Patients with liver failure, active bleeding, severe thrombocytopenia, ICU stay of less than 24<!--> <!-->hours or treated with other anticoagulants were excluded. Demographic variables, severity index (APACHE II), vasoactive drug use, adverse events, and catheter characteristics were recorded. Anticoagulation efficacy was assessed with filter duration. Statistical analysis was performed with SPSS v.28.0, with p&lt;<!--> <!-->0.05 as the significance level. The study was approved by the ethics committee and informed consent was obtained from the patients or their relatives.</div></div><div><h3>Results</h3><div>We studied 100 patients, 62% men, with a mean age of 63<!--> <!-->±<!--> <!-->14.5 years. The main causes of AKI were septic shock, hemorrhagic shock and Covid-19. The median ICU stay was 16 days (RIC 8-43), with intra-ICU mortality of 48%. Therapy lasted a median of 60.5<!--> <!-->hours (RIC 38-107). Only one patient presented bleeding, and in 26% the filter coagulated. There were no cases of citrate toxicity. Electrolyte complications included hypocalcemia (45%), hypokalemia (41%), hyponatremia (36%) and metabolic acidosis (30%).</div></div><div><h3>Conclusions</h3><div>Mechanical and metabolic complications are common in continuous renal replacement therapies with sodium citrate. It is essential for ICU staff to be aware of their high prevalence in order to optimize clinical management.</div></div>","PeriodicalId":43993,"journal":{"name":"Enfermeria Intensiva","volume":"36 3","pages":"Article 500544"},"PeriodicalIF":1.1,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of continuous glucose monitoring: A scoping review of accuracy, feasibility and nursing workload reduction in intensive care setting 使用连续血糖监测:范围审查的准确性,可行性和护理工作量减少在重症监护设置
IF 1.1 Q3 NURSING Pub Date : 2025-04-18 DOI: 10.1016/j.enfi.2025.500534
Marc Pañero-Moreno RN, MSc , Meritxell Muxella-Roson RN , Gemma Dubè-Llobet RN , Marta Cabrerizo-Jimenez RN , Eva Maria Guix-Comellas RN, MSN, PhD , Alberto Villamor-Ordozgoiti RN, MSN, PhD , Natalia Marsà-Perez RN

Background

Hyperglycemia is prevalent in intensive care units (ICUs), associated with increased mortality. Management involves frequent point-of-care glucose (POC-G), but continuous glucose monitoring (CGM) shows promise in improving glycemic control.

Aims

To explore the knowledge in the literature about the impact and accuracy of CGM in ICUs.

Design

A scoping review was conducted; PubMed, Web of Science, CINAHL, Scopus databases and Gray Literature covering the period from September 2018 to September 2024.

Methods

Data abstraction, quality appraisal, and narrative synthesis were carried out in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines.

Results

Of the 952 titles reviewed, 20 articles were included. Clinical outcomes were mean absolute relative difference (MARD), ranged from 9.3% to 20.6%. Additionally, there was a 30–71% reduction of POC-G measurements. Time in range (TIR) varied from 46.1% to 100%. Clarke Error Grid (CEG) analysis demonstrated that over 98% of the glucose values fell within zones A and B.

Conclusions

CGM in the ICU reduces nursing workload, enhances patient safety, and facilitates early intervention for abnormal glucose levels, demonstrating its feasibility, accuracy and effectiveness in critical care settings. Additional clinical trials are needed to validate these findings and establish optimal usage parameters.

Relevance to clinical practice

CGM came to stay in ICU. Therefore, it is crucial to start training critical care nurses in the use of CGM. This will enable us to maximize their benefits in terms of reducing nursing workload and enhancing patient safety.
背景:高血糖症在重症监护病房(icu)很普遍,与死亡率增加有关。治疗包括频繁的即时血糖(pocc - g),但持续血糖监测(CGM)显示出改善血糖控制的希望。目的探讨CGM在icu中的影响及准确性。进行了设计范围审查;PubMed, Web of Science, CINAHL, Scopus数据库和Gray Literature涵盖2018年9月至2024年9月。方法按照系统评价首选报告项目和范围评价扩展元分析(PRISMA-ScR)指南进行数据抽象、质量评价和叙事综合。结果952篇文献中,共纳入20篇。临床结果为平均绝对相对差(MARD),范围为9.3%至20.6%。此外,POC-G测量值降低了30-71%。范围内时间(TIR)从46.1%到100%不等。Clarke Error Grid (CEG)分析显示,超过98%的血糖值落在A区和b区。结论scgm在ICU中减少了护理工作量,提高了患者的安全性,促进了对血糖异常的早期干预,证明了其在重症监护环境中的可行性、准确性和有效性。需要额外的临床试验来验证这些发现并建立最佳使用参数。与临床实践的相关性ecgm来到ICU。因此,开始培训重症监护护士使用CGM至关重要。这将使我们能够在减少护理工作量和提高患者安全方面最大化他们的利益。
{"title":"The use of continuous glucose monitoring: A scoping review of accuracy, feasibility and nursing workload reduction in intensive care setting","authors":"Marc Pañero-Moreno RN, MSc ,&nbsp;Meritxell Muxella-Roson RN ,&nbsp;Gemma Dubè-Llobet RN ,&nbsp;Marta Cabrerizo-Jimenez RN ,&nbsp;Eva Maria Guix-Comellas RN, MSN, PhD ,&nbsp;Alberto Villamor-Ordozgoiti RN, MSN, PhD ,&nbsp;Natalia Marsà-Perez RN","doi":"10.1016/j.enfi.2025.500534","DOIUrl":"10.1016/j.enfi.2025.500534","url":null,"abstract":"<div><h3>Background</h3><div>Hyperglycemia is prevalent in intensive care units (ICUs), associated with increased mortality. Management involves frequent point-of-care glucose (POC-G), but continuous glucose monitoring (CGM) shows promise in improving glycemic control.</div></div><div><h3>Aims</h3><div>To explore the knowledge in the literature about the impact and accuracy of CGM in ICUs.</div></div><div><h3>Design</h3><div>A scoping review was conducted; PubMed, Web of Science, CINAHL, Scopus databases and Gray Literature covering the period from September 2018 to September 2024.</div></div><div><h3>Methods</h3><div>Data abstraction, quality appraisal, and narrative synthesis were carried out in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines.</div></div><div><h3>Results</h3><div>Of the 952 titles reviewed, 20 articles were included. Clinical outcomes were mean absolute relative difference (MARD), ranged from 9.3% to 20.6%. Additionally, there was a 30–71% reduction of POC-G measurements. Time in range (TIR) varied from 46.1% to 100%. Clarke Error Grid (CEG) analysis demonstrated that over 98% of the glucose values fell within zones A and B.</div></div><div><h3>Conclusions</h3><div>CGM in the ICU reduces nursing workload, enhances patient safety, and facilitates early intervention for abnormal glucose levels, demonstrating its feasibility, accuracy and effectiveness in critical care settings. Additional clinical trials are needed to validate these findings and establish optimal usage parameters.</div></div><div><h3>Relevance to clinical practice</h3><div>CGM came to stay in ICU. Therefore, it is crucial to start training critical care nurses in the use of CGM. This will enable us to maximize their benefits in terms of reducing nursing workload and enhancing patient safety.</div></div>","PeriodicalId":43993,"journal":{"name":"Enfermeria Intensiva","volume":"36 3","pages":"Article 500534"},"PeriodicalIF":1.1,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efecto de una intervención de musicoterapia en el estado de ánimo del enfermo crítico 音乐治疗干预对危重病人情绪的影响
IF 1.1 Q3 NURSING Pub Date : 2025-04-17 DOI: 10.1016/j.enfi.2025.500549
M. del Mar Vega Castosa MSN, M. del Carmen Jover Sancho MSN, PhD, Joan Trujols Albet PhD

Introduction

The critically ill patient is in a state of fragility, helplessness, and vulnerability that hinders the communication of their emotions and feelings. Music therapy could be a valid tool to improve mood. The main objective was to evaluate the effect on mood of an individualized music therapy intervention compared to standard care and analyze the impact on pain and hemodynamic variables.

Methodology

Randomized, parallel, and open clinical trial. Patients were randomized into the experimental group, receiving combined music therapy and standard care, or the control group, receiving standard care only. The study population consisted of patients admitted to the Intensive Care Unit with a Glasgow 15-11 T score, excluding those with confusion, agitation, and significant cognitive deficits. The primary variable was mood, assessed using the Profile of Mood States questionnaire. Secondary variables included pain, heart rate, blood pressure, respiratory rate, and oxygen saturation.

Results

A total of 151 patients were included, randomly distributed into the experimental group (n = 75) and the control group (n = 76). Mood improvement was significant in all 6 subscales of the Profile of Mood States questionnaire, in the time effect between pre- and post-intervention assessment, and in the time effect by group interaction for Anger (p = 0.020), Fatigue (p = 0.002), Vigor (p = 0.029), and Tension (p = 0.042), indicating that the improvement was related to the music therapy intervention in the experimental group. Following the music therapy intervention, a decrease in pain (p = 0.024) and heart rate (p = 0.017) was observed in the time effect, and an increase in systolic blood pressure (p = 0.004) was related to the music therapy intervention.

Discussion

This clinical trial demonstrates that music therapy, with a personalized music intervention, has a positive effect on the mood of critically ill patients. Further lines of research are needed to continue advancing scientific knowledge and develop news forms of assistance to improve mood.
危重病人处于脆弱、无助和脆弱的状态,这阻碍了他们的情绪和感受的交流。音乐疗法可能是改善情绪的有效工具。主要目的是评估与标准治疗相比,个体化音乐治疗干预对情绪的影响,并分析对疼痛和血流动力学变量的影响。方法:随机、平行、开放临床试验。患者被随机分为实验组和对照组,实验组接受音乐治疗和标准治疗,对照组只接受标准治疗。研究人群包括格拉斯哥15-11 T评分入重症监护病房的患者,排除那些有精神错乱、躁动和显著认知缺陷的患者。主要变量是情绪,使用情绪状态问卷进行评估。次要变量包括疼痛、心率、血压、呼吸频率和血氧饱和度。结果共纳入151例患者,随机分为实验组(n = 75)和对照组(n = 76)。情绪状态量表的6个分量表、干预前和干预后评估的时间效应以及小组互动对愤怒(p = 0.020)、疲劳(p = 0.002)、活力(p = 0.029)和紧张(p = 0.042)的时间效应均有显著改善,表明实验组的改善与音乐治疗干预有关。音乐治疗干预后,疼痛减轻(p = 0.024),心率降低(p = 0.017),收缩压升高(p = 0.004)与音乐治疗干预有关。本临床试验表明,音乐治疗,与个性化的音乐干预,对危重病人的情绪有积极的影响。需要进一步的研究来继续推进科学知识,并开发新的帮助改善情绪的方式。
{"title":"Efecto de una intervención de musicoterapia en el estado de ánimo del enfermo crítico","authors":"M. del Mar Vega Castosa MSN,&nbsp;M. del Carmen Jover Sancho MSN, PhD,&nbsp;Joan Trujols Albet PhD","doi":"10.1016/j.enfi.2025.500549","DOIUrl":"10.1016/j.enfi.2025.500549","url":null,"abstract":"<div><h3>Introduction</h3><div>The critically ill patient is in a state of fragility, helplessness, and vulnerability that hinders the communication of their emotions and feelings. Music therapy could be a valid tool to improve mood. The main objective was to evaluate the effect on mood of an individualized music therapy intervention compared to standard care and analyze the impact on pain and hemodynamic variables.</div></div><div><h3>Methodology</h3><div>Randomized, parallel, and open clinical trial. Patients were randomized into the experimental group, receiving combined music therapy and standard care, or the control group, receiving standard care only. The study population consisted of patients admitted to the Intensive Care Unit with a Glasgow 15-11<!--> <!-->T score, excluding those with confusion, agitation, and significant cognitive deficits. The primary variable was mood, assessed using the Profile of Mood States questionnaire. Secondary variables included pain, heart rate, blood pressure, respiratory rate, and oxygen saturation.</div></div><div><h3>Results</h3><div>A total of 151 patients were included, randomly distributed into the experimental group (n<!--> <!-->=<!--> <!-->75) and the control group (n<!--> <!-->=<!--> <!-->76). Mood improvement was significant in all 6 subscales of the Profile of Mood States questionnaire, in the time effect between pre- and post-intervention assessment, and in the time effect by group interaction for Anger (p<!--> <!-->=<!--> <!-->0.020), Fatigue (p<!--> <!-->=<!--> <!-->0.002), Vigor (p<!--> <!-->=<!--> <!-->0.029), and Tension (p<!--> <!-->=<!--> <!-->0.042), indicating that the improvement was related to the music therapy intervention in the experimental group. Following the music therapy intervention, a decrease in pain (p<!--> <!-->=<!--> <!-->0.024) and heart rate (p<!--> <!-->=<!--> <!-->0.017) was observed in the time effect, and an increase in systolic blood pressure (p<!--> <!-->=<!--> <!-->0.004) was related to the music therapy intervention.</div></div><div><h3>Discussion</h3><div>This clinical trial demonstrates that music therapy, with a personalized music intervention, has a positive effect on the mood of critically ill patients. Further lines of research are needed to continue advancing scientific knowledge and develop news forms of assistance to improve mood.</div></div>","PeriodicalId":43993,"journal":{"name":"Enfermeria Intensiva","volume":"36 3","pages":"Article 500549"},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eficacia del acompañamiento familiar y de medidas ambientales para reducir la incidencia de delirio en una unidad de agudos cardiovasculares: un estudio cuasi-experimental. Reducir el delirio sin fármacos es posible, es mejor 家庭陪伴和环境措施在减少急性心血管单位谵妄发生率方面的有效性:一项准实验研究。在没有药物的情况下减少精神错乱是可能的,而且更好
IF 1.1 Q3 NURSING Pub Date : 2025-04-04 DOI: 10.1016/j.enfi.2025.500546
Luis Guerra-Sánchez PhD , Sara González-Alfonso RN , Pablo Lerma-Lara RN , Miguel Bernardino-Santos RN , Rosario Cortijo-González RN , Soraya Bustamante-González RN

Introduction

The occurrence of delirium casts a shadow over the prognosis of patients, especially the critically ill. Prevention and treatment of delirium is more effective and with fewer adverse effects with multicomponent interventions than with pharmacological measures alone. The objective was to assess whether a non-pharmacological care-related intervention can reduce the incidence of delirium in an acute cardiovascular care unit.

Methods

Quasi-experimental study (before/after). ‘Before’: From November 2018 to March 2019, 190 patients aged 18 years and older, admitted to an acute cardiovascular care unit, were assessed using the Confusion Assessment Method for the ICU. From April to November 2019, a series of actions related to the physical environment and accompaniment were implemented. The ‘after’ started in November 2019 and 189 patients were assessed until early March 2020.

Results

The incidence of delirium before introducing the actions was 11,6%, which fell to 4,2% (p = 0,012) after the actions.

Discussion

Management of delirium includes effective diagnosis, delirium prevention activities and treatment, which ideally should be free of side effects.

Conclusions

The implementation of a bundle of measures related to environmental changes and involving the family, significantly reduced the incidence of delirium, to less than half.
谵妄的发生给患者,尤其是危重患者的预后蒙上了阴影。多组分干预预防和治疗谵妄比单用药物治疗更有效,副作用更少。目的是评估非药物护理相关干预是否可以减少急性心血管病房谵妄的发生率。方法准实验研究(前后对照)。“之前”:从2018年11月到2019年3月,使用ICU混淆评估法对190名18岁及以上的急性心血管护理病房患者进行评估。2019年4月至11月,实施了一系列与物理环境和伴奏相关的行动。“之后”从2019年11月开始,直到2020年3月初,对189名患者进行了评估。结果麻醉前谵妄发生率为11.6%,麻醉后谵妄发生率为4.2% (p = 0.012)。谵妄的管理包括有效的诊断、谵妄的预防活动和治疗,最好是无副作用。结论实施与环境变化相关且涉及家庭的一揽子措施,谵妄的发生率明显降低,降至一半以下。
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引用次数: 0
Bacteriemia asociada a catéter venoso central en el paciente crítico: epidemiología y factores de riesgo 危重病人中与中央静脉导管相关的细菌性血症:流行病学和危险因素
IF 1.1 Q3 NURSING Pub Date : 2025-04-04 DOI: 10.1016/j.enfi.2025.500538
Esther Mancheño-Maciá PhD , Beatriz Muñoz-Sánchez RN , Inés González-Sánchez PhD , Marina Leal-Clavel RN MsN , Vanesa Escudero-Ortiz PhD

Introduction

Central venous catheter-related bacteremia is a common nosocomial infection in intensive care units (ICU), the prevalence is worrying. In recent years, due to Covid-19, the number of central venous catether's patients, treated with immunosuppressive drugs, has been increased. Our objective was to determine the prevalence of central catheter bacteremia in ICU, during 2022, as well as to determine associated risk factors.

Method

Descriptive cross-sectional study in ICU of hospita (HGU Dr. Balmis Hospital Alicante, Spain). Were included 466 patients admitted to ICU in 2022. Sociodemographic, clinical, catheter-related data and APACHE-II and q-SOFA scale scores were collected.

Results

The prevalence of bacteriemia was 3.65%. Significant factors associated with bacteriemia were the number of catheters inserted in each patient (p < 0.001) and the use of immunosuppressive drugs (p = 0.002). Patients who had a peripherally inserted catheter (PICC) had a lower probability of develop bacteriemia and patients with conventional catheter and PICC had a higher probability. The rest of the variables, including Covid-19, without significant differences.

Discussion and conclusions

In line with other authors, we can affirm that the administration of immunosuppressive drugs is a risk factor of central venous catheter-related bacteremia; A correct risk-benefit assessment is recommended when prescribing these drugs, in Covid's patients the biological drug tocilizumab could be the recommended one. An increase by one unit in the number of catheters inserted causes a 5-fold increase in probability of developing bacteremia (Odds ratio: 4.984, 95% confidence interval 2.984-9.136). Covid-19, sex, age, comorbidities and q-SOFA and APACHE-II scores do not seem to show a relationship whith bacteremia and PICCs devices do seem to be safer versus conventional CVCs.
中心静脉导管相关性菌血症是重症监护病房(ICU)常见的院内感染,其发病率令人担忧。近年来,由于Covid-19,中心静脉导管患者使用免疫抑制药物治疗的人数有所增加。我们的目的是确定2022年ICU中心导管菌血症的患病率,并确定相关的危险因素。方法对西班牙阿利坎特HGU Balmis医院ICU进行描述性横断面研究。纳入2022年ICU住院患者466例。收集社会人口学、临床、导管相关数据以及APACHE-II和q-SOFA量表评分。结果细菌血症发生率为3.65%。与菌血症相关的重要因素是每位患者插入导管的数量(p <;0.001)和使用免疫抑制药物(p = 0.002)。采用外周导管(PICC)的患者发生菌血症的概率较低,而采用常规导管和PICC的患者发生菌血症的概率较高。其他变量,包括Covid-19,没有显著差异。讨论与结论与其他作者一致,我们可以肯定免疫抑制药物的使用是中心静脉导管相关性菌血症的危险因素;在处方这些药物时,建议进行正确的风险-效益评估,在Covid患者中,生物药物tocilizumab可能是推荐的药物。插入导管数量每增加一个单位,发生菌血症的可能性增加5倍(优势比:4.984,95%置信区间为2.984-9.136)。Covid-19、性别、年龄、合并症以及q-SOFA和APACHE-II评分似乎没有显示出与菌血症的关系,PICCs设备似乎比传统cvc更安全。
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引用次数: 0
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Enfermeria Intensiva
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