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From Coverage to Coherence: A Design-Based Reflection on Constructive Alignment through Science Practices and Causal–Mechanistic Reasoning 从覆盖到连贯:通过科学实践和因果机制推理对建设性一致性的基于设计的反思
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-24 DOI: 10.1021/acs.jchemed.5c01088
Samuel Pazicni*, , , Jaclyn M. Trate, , and , Stephen B. Block, 

This design-based reflection examines how integrating science practices and causal–mechanistic reasoning can strengthen constructive alignment in undergraduate chemistry. Using an evidence-centered design framework, we describe how a large-enrollment General Chemistry course was restructured around multidimensional learning performances─statements that integrate core ideas, practices, and causal reasoning into purposeful knowledge use. Rather than organizing instruction by topics or procedures, we aligned the curriculum, instruction, and assessment with the epistemic work of chemistry: modeling, explaining, and predicting phenomena. We illustrate this approach with a learning performance on phase changes, using it to show how coherence across curricular activity system components (e.g., interactive texts, collaborative tasks, assessments) was intentionally designed to support engagement with science practices and causal reasoning. Conjecture maps clarify the design logic and guide iterative refinement. Two vignettes (on delocalized bonding and chemical equilibrium) highlight emergent learning progressions that surfaced in this work. We conclude with four strategies to help instructors and departments adapt the approach. When anchored in science practices and disciplinary reasoning, constructive alignment becomes not just a design principle but an epistemic infrastructure that can support coherence, equity, and inclusion.

这个基于设计的反思探讨了如何整合科学实践和因果机制推理可以加强本科化学的建设性一致性。我们采用以证据为中心的设计框架,描述了如何围绕多维学习表现(将核心思想、实践和因果推理整合到有目的的知识使用中的陈述)对大规模招生的普通化学课程进行重组。我们不是按主题或程序组织教学,而是将课程、教学和评估与化学的认知工作结合起来:建模、解释和预测现象。我们用一个关于阶段变化的学习表现来说明这种方法,用它来展示如何有意地设计跨课程活动系统组件(例如,互动文本,协作任务,评估)的一致性,以支持与科学实践和因果推理的参与。猜想图阐明了设计逻辑,指导迭代改进。两个小插曲(关于离域键和化学平衡)突出了在这项工作中出现的紧急学习过程。我们总结了四种策略来帮助教师和院系适应这种方法。当锚定在科学实践和学科推理中时,建设性的一致性就不仅仅是一种设计原则,而是一种认知基础设施,可以支持一致性、公平性和包容性。
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引用次数: 0
Virtual Reality in the Caribbean Classroom: Boosting Undergraduate Chemistry Motivation and Performance with 3D Virtual Reality 加勒比课堂中的虚拟现实:用3D虚拟现实提高本科化学动机和表现
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-24 DOI: 10.1021/acs.jchemed.5c00948
Donna Hitlal*, , , Denise Beckles, , and , Diane Thurab-Nkhosi, 

Student motivation plays a vital role in academic success, particularly in chemistry, which many undergraduates find challenging. This study evaluated the impact of 3D Immersive Virtual Reality (IVR) on motivation and performance among first-year undergraduate chemistry students at The University of the West Indies, St. Augustine. For motivation, a quasi-experimental pretest-post-test design was used while, for performance, an experimental post-test only design was used. Students were assigned to either a control group, receiving traditional instruction, or a test group, experiencing the same instruction supplemented with 3D IVR using MEL VR software and head-mounted displays. Motivation was measured using the Chemistry Motivation Questionnaire II (CMQ-II), which assessed five dimensions: intrinsic motivation, self-efficacy, self-determination, grade motivation, and career motivation. Performance was measured with a 30-question chemistry quiz, given after the VR exposure time was completed. For motivation, the test group showed statistically significant gains in overall motivation and in four of the five subscales, while the control group showed no significant change. Additionally, the test group outperformed the control group in the post-test comparison. These findings highlight the potential of IVR to enhance chemistry motivation and performance in higher education and suggest broader applications for immersive technologies in STEM teaching across Caribbean institutions.

学生的学习动机在学业成功中起着至关重要的作用,尤其是在化学方面,许多本科生都觉得这门课很有挑战性。这项研究评估了3D沉浸式虚拟现实(IVR)对圣奥古斯丁西印度群岛大学一年级化学本科学生的动机和表现的影响。在动机方面,采用准实验的前测后测设计,而在绩效方面,只采用实验的后测设计。学生们被分配到对照组,接受传统的教学,或者是测试组,使用MEL VR软件和头戴式显示器体验同样的教学,辅以3D IVR。动机采用化学动机问卷II (CMQ-II)进行测量,评估了五个维度:内在动机、自我效能、自我决定、成绩动机和职业动机。在VR曝光时间结束后,通过30道化学测试来衡量他们的表现。在动机方面,实验组在总体动机和五个子量表中的四个都有统计学意义上的显著提高,而对照组则没有显著变化。此外,实验组在测试后比较中表现优于对照组。这些发现强调了IVR在提高高等教育化学动机和表现方面的潜力,并建议将沉浸式技术更广泛地应用于加勒比院校的STEM教学。
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引用次数: 0
Giving Feedback on a Draft Assessment: Does It Improve Student Uptake of Feedback and Performance in Forensic Chemistry? 在评估草案中给予反馈:它能提高学生对反馈的吸收和法医化学的表现吗?
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-24 DOI: 10.1021/acs.jchemed.5c01369
Hilary J. Hamnett*,  and , Nitin L. Seetohul, 

Considerable tutor effort is put into providing feedback to students on assessments; however, low rates of engagement are a known problem in higher education. This study measured the impact of a new feedback design in a forensic chemistry assessment on engagement and grade distribution across three cohorts (2023–25) using data from a virtual learning environment. In the assessment, students examine a mock police exhibit, a questioned document and two pens, in a laboratory practical using Raman and FTIR spectroscopy and a Visual Spectral Comparator, and then write the results up in an expert witness statement. Under the new feedback design, a feedback opportunity was given on a draft submission of the statement, rather than after the final summative submission. Across ∼100 students in each cohort, the rate of feedback uptake improved from 7% to 98%. Although the difference between the mean grades between cohorts was not statistically significant, the grade profile improved. Students in 2023/24 also completed an online survey to assess their perceptions of the new feedback design. This revealed that the new design increased their confidence when tackling the final assessment. A face-to-face session where students could clarify and discuss any feedback comments with the tutor enabled the feedback to be viewed as a collaborative and two-way process.

导师在向学生提供评估反馈方面付出了相当大的努力;然而,参与率低是高等教育中一个众所周知的问题。本研究使用虚拟学习环境中的数据,测量了法医化学评估中新的反馈设计对三个队列(2023-25)的参与度和成绩分布的影响。在评估中,学生们在实验室中使用拉曼光谱和FTIR光谱以及视觉光谱比较仪实际检查一个模拟警察展览,一份被质疑的文件和两支笔,然后将结果写在专家证人陈述中。根据新的反馈设计,在提交声明草案时提供反馈机会,而不是在最后的总结性提交之后。在每组约100名学生中,反馈接受率从7%提高到98%。虽然队列之间的平均评分差异没有统计学意义,但评分情况有所改善。2023/24学年的学生还完成了一项在线调查,以评估他们对新反馈设计的看法。结果表明,新设计增加了他们在最终评估时的信心。面对面的会议,学生可以澄清和讨论任何反馈意见与导师使反馈被视为一个合作和双向的过程。
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引用次数: 0
Interdisciplinary Project-Based Learning Activity Design for Investigating Nitrogen Fixation through a Scientific Exploration Lens 基于跨学科项目的科学探索视角下研究固氮的学习活动设计
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-23 DOI: 10.1021/acs.jchemed.5c00888
Jianjun Wu*, , , Chen Wang, , , Fengjun Zhao, , and , Songbai Wang*, 

This study formulates interdisciplinary project-based learning (IDPBL) activities for high school third-year students, centered on the theme of “Investigating Nitrogen Fixation through a Scientific Exploration Lens”. The project systematically addresses the mechanisms of biological and chemical nitrogen fixation, industrial condition optimization, and biomimetic innovation design. Through four key instructional modules, including exploration of molecular structures, analysis of condition optimization, biomimetic catalyst design, and future prospects, the activity integrates visualization tools and cutting-edge case studies to guide students in understanding the stability of the nitrogen–nitrogen triple bond, the selection rationale for ammonia synthesis reaction conditions, and the significance of interdisciplinary integration. Implementation results demonstrate that students successfully established a “structure determines properties” cognitive model, mastered thermodynamic and kinetic approaches to optimizing industrial production, and proposed innovative solutions such as electrochemical biomimetic nitrogen fixation. The findings validate the remarkable effectiveness of IDPBL in enhancing students’ scientific literacy, innovation capacity, and problem-solving skills, providing a practical reference for science education reform.

本研究以“用科学探索的视角探究固氮”为主题,为高三学生制定了跨学科项目式学习(IDPBL)活动。本项目系统研究生物和化学固氮机理、工业条件优化、仿生创新设计。该活动通过分子结构探索、条件优化分析、仿生催化剂设计和未来展望四个重点教学模块,结合可视化工具和前沿案例研究,引导学生了解氮-氮三键的稳定性、氨合成反应条件的选择原理以及跨学科整合的意义。实施结果表明,学生成功建立了“结构决定性质”的认知模型,掌握了优化工业生产的热力学和动力学方法,并提出了电化学仿生固氮等创新解决方案。研究结果验证了IDPBL在提高学生科学素养、创新能力和解决问题能力方面的显著效果,为科学教育改革提供了实践参考。
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引用次数: 0
Improved Continuous Flow Synthesis of a Diazo Dye in a Teaching Laboratory and Its Digitalization 重氮染料在教学实验室的改进连续流合成及其数字化
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-23 DOI: 10.1021/acs.jchemed.5c00637
Yicheng Zhou, , , Xuhao Huang, , , Yihui Tang, , , Yunyan Zhang, , , Yanan Zhao, , , Jinli Cao, , and , Jiajun Yan*, 

In recent years, flow chemistry has gained recognition as an efficient and safer method for chemical synthesis in research laboratories and the pharmaceutical industry. Despite its advantages, its integration into educational settings has been limited to a select few institutions. This slow adoption is primarily due to the challenge of transitioning from traditional batch-based experiments, which have been entrenched in curricula for decades. In our efforts to modernize chemical education, we implemented a diazonium-based laboratory experiment from the literature to teach fundamental concepts of organic reactions and chemical kinetics. However, ensuring the reproducibility of results in a classroom setting proved difficult. This work looks into the key factors affecting reproducibility in this context, especially the reaction protocol and kinetics. We discovered from earlier studies on azo coupling that the pH is critical to the success of this teaching experiment. With the updated protocol and corrected kinetics, we observed an improvement in student performance. Based on the kinetics, we developed a digital twin of the experiment, which was evaluated by students taking this class. We aim to teach students to critically evaluate literature while expanding access and fostering equity in chemical education, particularly within underrepresented communities.

近年来,流动化学作为一种高效、安全的化学合成方法在研究实验室和制药工业中得到了认可。尽管它有优势,但它与教育环境的结合仅限于少数几个机构。这种缓慢的采用主要是由于从传统的基于批处理的实验过渡的挑战,这种实验已经在课程中根深蒂固了几十年。在化学教育现代化的努力中,我们从文献中实施了一个以重氮为基础的实验室实验,以教授有机反应和化学动力学的基本概念。然而,在教室环境中确保结果的可重复性证明是困难的。这项工作着眼于在这种情况下影响再现性的关键因素,特别是反应方案和动力学。我们从早期偶氮偶联的研究中发现,pH值对这次教学实验的成功至关重要。通过更新的方案和修正的动力学,我们观察到学生的表现有所改善。基于动力学,我们开发了一个实验的数字双胞胎,并由参加本课程的学生进行评估。我们的目标是教会学生批判性地评价文学,同时扩大化学教育的机会和促进公平,特别是在代表性不足的社区。
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引用次数: 0
Making Context-Driven Connections in General Chemistry: Application of Case Studies Combined with Creative Exercises 在普通化学中建立情境驱动的联系:案例研究结合创造性练习的应用
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-23 DOI: 10.1021/acs.jchemed.5c01258
Sreekumar Pankajakshan*, , , Tanya Zaki, , , Busra Mahmutoglu, , , Chinnu Sebastian, , , Reinad Abu Rabah, , and , Samar Fadl, 

Case studies (CS) and creative exercises (CEs) are two established methodologies grounded in constructivist theory, designed to promote student-centric learning and assessment. Cases provide an engaging real-life context to conceptual knowledge, while CEs, produced as statements deciphering a given situation/prompt, encourage the learner to make meaningful linkages across various concepts, making knowledge more coherent and structured. Natural contexts are typically concept-rich situations, and the study described here explores an integrated application of both methods to offer general chemistry students a context-driven vehicle for problem-solving, linking, and cross-cutting of concepts. Three case studies were developed for this purpose and were deployed as team-based assessments. The CE statements produced for each were coded, and Gephi visual maps were produced to analyze the conceptual linkages formed by students in each of the three contexts. The data showed that the students made effective usage of CE as a tool to provide conceptual explanation of the various tangible facets of the given contexts, while also generating integrated and cross-cutting responses. The impact of these exercises on summative learning was qualitatively assessed using a CE-problem in the final exam of the course. Student feedback indicated an overall positive impact on both learning and attitudes toward the subject.

案例研究(CS)和创造性练习(CEs)是两种建立在建构主义理论基础上的方法,旨在促进以学生为中心的学习和评估。案例为概念性知识提供了一个引人入胜的现实生活背景,而ce作为解读给定情况/提示的陈述,鼓励学习者在各种概念之间建立有意义的联系,使知识更加连贯和结构化。自然情境通常是概念丰富的情境,这里描述的研究探索了两种方法的综合应用,为普通化学学生提供了一种情境驱动的工具,用于解决问题,链接和交叉概念。为此目的编写了三个案例研究,并作为基于小组的评估部署。为每一种情境生成的CE语句都被编码,并生成Gephi可视化地图来分析学生在每一种情境中形成的概念联系。数据显示,学生们有效地利用语言表达作为一种工具,对给定语境的各种有形方面提供概念性解释,同时也产生了综合和交叉的反应。这些练习对总结性学习的影响使用课程期末考试中的ce问题进行定性评估。学生的反馈表明,这对学习和对学科的态度都产生了总体上的积极影响。
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引用次数: 0
Getting Serious about Useful Chemistry Learning: A Case for Attending to Epistemological Messaging 认真对待有用的化学学习:一个关注认识论信息传递的案例
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-23 DOI: 10.1021/acs.jchemed.5c00829
Ryan L. Stowe*, 

In this Perspective, I consider how our field can take principled actions to align our ways of designing and refining courses with our oft-stated goal for chemistry learning to be useful in daily life. To do so, I make three interrelated arguments. First, I argue achieving this goal will require a particular focus on epistemologies: “[people’s] systems of beliefs [tacit or explicit] about (1) the nature of knowledge and (2) the processes of knowing” [ Educ. Psychol. 2011, 46 (3), 141]. Specifically, this goal requires that students (tacitly) experience symmetry between ways of knowing and learning valued in-class and ways of knowing and learning useful in life beyond school. Second, we should compile our sense of useful epistemologies from empirical accounts of people and communities using chemistry to advance personally or professionally meaningful goals: a claim that way of thinking X is useful to dentists should be supported by observations of or interviews with dentists, for example. Third, achieving this goal requires understanding how our course designs communicate allowed epistemologies. Such understandings will enable us to refine our courses such that they better approximate aspects of students’ post-school daily lives.

从这个角度来看,我考虑我们的领域如何采取有原则的行动,使我们设计和改进课程的方式与我们经常提出的化学学习在日常生活中有用的目标保持一致。为此,我提出了三个相互关联的论点。首先,我认为实现这一目标将需要特别关注认识论:“[人们]关于(1)知识的本质和(2)认识过程的[隐性或显性]信念系统”[Educ.]精神病学杂志,2011,46(3),141。具体来说,这一目标要求学生(心照不宣地)体验到课堂上有价值的认识和学习方式与学校以外生活中有用的认识和学习方式之间的对称。其次,我们应该从人们和社区使用化学来推进个人或专业有意义的目标的经验叙述中整理出有用的认识论:例如,认为X思维方式对牙医有用的说法应该得到对牙医的观察或采访的支持。第三,实现这一目标需要理解我们的课程设计如何传达允许的认识论。这样的理解将使我们能够改进我们的课程,使它们更好地接近学生毕业后的日常生活。
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引用次数: 0
Exploring the Drug Development Process Using Fischer Esterification: An Introductory Organic Chemistry Laboratory Experiment 探索药物开发过程中使用费舍尔酯化:一个入门有机化学实验室实验
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-22 DOI: 10.1021/acs.jchemed.5c01048
Barbora Morra*,  and , Alicia M. Battaglia, 

A drug discovery project has been successfully implemented into a first-year undergraduate organic chemistry course. In this experiment, students play the role of medicinal chemists in the drug development process, in which they are responsible for synthesizing a small library of salicylic acid and ester derivatives and analyzing the antibacterial properties of their compounds against Escherichia coli, for the purpose of finding a compound with relevant biological activity. By using synthetic techniques, peer collaboration, student-led decision making, and biological activity assessment, students are required to work together and think critically about their results to solve an interdisciplinary research problem.

一个药物发现项目成功实施到本科一年级有机化学课程中。在本实验中,学生在药物开发过程中扮演药物化学家的角色,负责合成水杨酸及其酯类衍生物的一个小文库,并分析其化合物对大肠杆菌的抑菌性能,以寻找具有相关生物活性的化合物。通过使用综合技术、同伴合作、学生主导的决策和生物活性评估,学生需要一起工作,批判性地思考他们的结果,以解决跨学科的研究问题。
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引用次数: 0
Ultrasensitive Detection of Gallic Acid via Synergistic Enhancement of Single-Walled Carbon Nanotubes@Zeolitic Imidazolate Framework-8: Comprehensive Innovative Experiment for Undergraduates 单壁碳协同增强Nanotubes@Zeolitic咪唑酸框架超灵敏检测没食子酸-8:大学生综合创新实验
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-22 DOI: 10.1021/acs.jchemed.5c01516
Hongyuan Zhao*, , , Mengyuan Zhao, , , Jing Tang, , , Zhongming Song, , and , Zirong Li*, 

Gallic acid (GA) with strong antioxidant and antibacterial properties has been widely used in the food and pharmaceutical industries. However, excessive GA may induce gastrointestinal irritation and impose metabolic burdens on the liver and kidneys. Herein, we developed a novel electrochemical sensor based on the single-walled carbon nanotubes@zeolitic imidazolate framework-8 decorated electrode (SCT@ZMF/GCE) for the ultrasensitive detection of GA. SCT with a hollow nanotube structure provided excellent conductivity properties because of the interconnected conductive carbon networks, and ZMF nanoparticles with high porosity exhibited strong adsorption capacity for GA molecules. SCT@ZMF/GCE displayed exceptional GA detection (Linear detection range: 0.1–30 μM; limit of detection: 7.84 nM). This comprehensive innovative experiment was designed for senior undergraduate students majoring in materials science, chemistry, and other related fields. This experiment contains a literature review, nanocomposite preparation, material characterization, electrochemical detection, and data processing. Integrating this experiment into undergraduate teaching will help participants achieve the following objectives: (1) understanding the importance of GA concentration for human health; (2) designing a simple, low-cost, and innovative GA analysis method; (3) optimizing the electrochemical detection condition; and (4) mastering the GA detection mechanism and strengthening the experimental skills and scientific literacy.

没食子酸(GA)具有较强的抗氧化和抗菌性能,在食品和制药工业中得到了广泛的应用。然而,过量的GA可能引起胃肠道刺激,并对肝脏和肾脏造成代谢负担。在此,我们开发了一种基于单壁碳nanotubes@zeolitic咪唑酸框架-8修饰电极(SCT@ZMF/GCE)的新型电化学传感器,用于GA的超灵敏检测。具有中空纳米管结构的SCT由于相互连接的导电碳网络而具有优异的导电性能,具有高孔隙率的ZMF纳米颗粒对GA分子具有很强的吸附能力。SCT@ZMF/GCE显示异常的GA检测(线性检测范围0.1 ~ 30 μM,检出限7.84 nM)。本综合创新实验是为材料科学、化学等相关专业本科高年级学生设计的。本实验包括文献综述、纳米复合材料制备、材料表征、电化学检测和数据处理。将本实验纳入本科教学将有助于参与者达到以下目标:(1)了解GA浓度对人体健康的重要性;(2)设计一种简单、低成本、创新的遗传分析方法;(3)优化电化学检测条件;(4)掌握遗传算法检测机制,增强实验技能和科学素养。
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引用次数: 0
Laboratory Safety for Chemistry Students, 3rd Edition (e-Textbook): A Free Resource for Integrated Chemical Safety Education 化学学生实验室安全,第三版(电子教科书):化学安全综合教育的免费资源
IF 2.9 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2025-12-22 DOI: 10.1021/acs.jchemed.5c01480
David C. Finster*, , , Marta Gmurczyk, , , Rachel Bocwinski, , and , Robert H. Hill Jr., 

The American Chemical Society (ACS) announces a free resource in e-Textbook format – Laboratory Safety for Chemistry Students, third Edition (LSCS3). LSCS3 is organized using the RAMP protocol - an acronym for Recognize hazards, Assess risks of hazards, Minimize risks of hazards, and Prepare for emergencies. This e-Textbook is designed with flexibility for undergraduate safety instruction. A supporting Web site describes quizzes, templates, and other features to facilitate using LSCS3.

美国化学会(ACS)公布了一个免费的电子教科书格式资源-化学学生实验室安全,第三版(LSCS3)。LSCS3是使用RAMP协议组织的,该协议是识别危险、评估危险风险、最小化危险风险和为紧急情况做好准备的首字母缩写。本电子教材设计灵活,适合本科生安全教学。一个支持网站描述了测验、模板和其他功能,以方便使用LSCS3。
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引用次数: 0
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Journal of Chemical Education
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