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Exploring Differences in Student Learning and Inquiry Skills Between Hands-On and Virtual Chemistry Laboratories 探索动手化学实验室和虚拟化学实验室在学生学习和探究技能方面的差异
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-09 DOI: 10.1021/acs.jchemed.4c00557
Shuangshuang Chen, Song Xue, Dan Yang, Liying Zhu, Mingzhan Ye
In the digital age, the integration of technology in educational practices, especially in chemistry, is increasingly advocated. However, research exploring the relative effectiveness of virtual laboratory (VL) environments compared to hands-on laboratory (HL) environments, particularly in enhancing students’ knowledge and inquiry skills, is rare. This study addresses this gap by evaluating the impact of VL and HL on junior high school students’ learning within the specific context of the Law of Conservation of Mass. By analyzing students’ performance through quantitative and qualitative assessments in knowledge tests and inquiry tasks, significant findings emerged. It was observed that the VL group demonstrated superior knowledge performance compared with the HL group. In terms of inquiry skills, while the overall performance was better in the HL group, particularly in planning and evidence collection, the VL group excelled in explanation and evaluation skills. These results suggest the potential benefit of implementing a blended approach, integrating both VL and HL, across various domains in chemistry education. Such an approach could leverage the unique advantages of each laboratory type to maximize student learning and engagement.
在数字时代,人们越来越提倡将技术融入教育实践,尤其是化学教育。然而,探索虚拟实验室(VL)环境与动手实验室(HL)环境的相对有效性,特别是在提高学生的知识和探究技能方面的有效性的研究却很少见。本研究针对这一空白,在质量守恒定律的特定背景下,评估了虚拟实验室和实践实验室对初中学生学习的影响。通过对学生在知识测试和探究任务中的表现进行定量和定性评估分析,得出了重要发现。结果表明,与高年级组相比,低年级组在知识方面的表现更胜一筹。在探究技能方面,虽然高年级组的整体表现更好,特别是在计划和证据收集方面,但自愿学习组在解释和评价技能方面表现出色。这些结果表明,在化学教育的各个领域实施混合式教学法,将虚拟语言和普通语言结合起来,可能会带来益处。这种方法可以利用每种实验室类型的独特优势,最大限度地提高学生的学习和参与度。
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引用次数: 0
“Synthetic Map”: A Graphic Organizer Inspired by Artificial Neural Network Paradigms for Learning Organic Synthesis "合成地图":学习有机合成的人工神经网络范式启发下的图形组织器
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-09 DOI: 10.1021/acs.jchemed.4c00592
Carlos Luque-Corredera, Elena Bartolomé, Ben Bradshaw
Organic Chemistry is widely recognized as a challenging subject, with the design of syntheses and retrosyntheses identified as particularly difficult tasks. Inspired by the success of artificial neural networks in machine learning, we propose a framework that leverages similar principles to enhance the teaching and learning of organic synthesis. In this paper, we introduce a novel teaching tool, the “Synthetic Map”, that attempts to visually recreate an expert’s mental map and conceptual understanding of organic synthesis built over years of experience. The educational benefits of the Synthetic Map were evaluated through its implementation in an Organic Chemistry course of a Pharmacy degree over two years. The new tool promoted students’ learning by providing a mental organizer fostering a deeper understanding of the subject and empowering students to design and execute effective synthetic strategies.
有机化学被公认为是一门具有挑战性的学科,其中合成设计和逆合成被认为是特别困难的任务。受人工神经网络在机器学习领域取得成功的启发,我们提出了一个框架,利用类似的原理来提高有机合成的教学效果。在本文中,我们介绍了一种新颖的教学工具--"合成地图",它试图直观地再现专家的思维导图和多年经验积累的对有机合成的概念理解。通过在药学学位的有机化学课程中实施该工具两年,我们对 "合成地图 "的教育效益进行了评估。这一新工具为学生提供了一个思维组织器,有助于他们加深对该学科的理解,并使学生能够设计和执行有效的合成策略,从而促进了学生的学习。
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引用次数: 0
A Laboratory Class: Constructing DNA Molecular Circuits for Cancer Diagnosis 实验课:构建用于癌症诊断的 DNA 分子电路
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-09 DOI: 10.1021/acs.jchemed.4c00675
Andrea C. Bardales, Quynh Vo, Dmitry M. Kolpashchikov
It has been shown that active learning strategies are effective in teaching complex STEM concepts. In this study, we developed and implemented a laboratory experiment for teaching the concepts of Boolean logic gates, molecular beacon probes, molecular computing, DNA logic gates, microRNA, and molecular diagnosis of hepatocellular carcinoma, which are related to DNA molecular computing, an interdisciplinary cutting-edge research technology in biochemistry, synthetic biology, computer science, and medicine. The laboratory experience takes about 110–140 min and consists of a multiple-choice pretest (15 min), introductory lecture (20 min), wet laboratory experiment (60–90 min), and a post-test (15 min). Students are tasked to experimentally construct three molecular logic circuits made of DNA oligonucleotides and use them for the fluorescence-based detection of microRNA markers related to diagnostics of hepatocellular carcinoma. The class was taught to undergraduate students from freshman to senior academic levels majoring in chemistry, biochemistry, biotechnology, and biomedical sciences. Students were engaged during the session and motivated to learn more about the research technology. A comparison of students’ scores on the pretest and post-test demonstrated improvement in knowledge of the concepts taught. Visual observation of the fluorescence readout led to a straightforward interpretation of the results. The laboratory experiment is portable; it uses inexpensive nontoxic reagents and thus can be employed outside a laboratory room for outreach and science popularization purposes.
事实证明,主动学习策略在教授复杂的 STEM 概念时非常有效。在本研究中,我们开发并实施了一个实验室实验,用于教授布尔逻辑门、分子信标探针、分子计算、DNA 逻辑门、microRNA 和肝细胞癌的分子诊断等概念,这些概念与 DNA 分子计算有关,是生物化学、合成生物学、计算机科学和医学领域的跨学科前沿研究技术。实验体验耗时约 110-140 分钟,包括选择题前测(15 分钟)、介绍性讲座(20 分钟)、湿实验室实验(60-90 分钟)和后测(15 分钟)。学生的任务是通过实验构建三个由 DNA 寡核苷酸组成的分子逻辑电路,并利用它们对与肝细胞癌诊断相关的 microRNA 标记进行荧光检测。授课对象为化学、生物化学、生物技术和生物医学专业的大一至大四本科生。学生们在课堂上非常投入,并积极主动地学习更多有关研究技术的知识。通过比较学生在前测和后测的成绩,可以看出他们对所学概念的了解有所提高。对荧光读数的肉眼观察可直接解释结果。该实验室实验便于携带;它使用廉价的无毒试剂,因此可在实验室外用于推广和科普目的。
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引用次数: 0
Integrated Instructions and Solvent Polarity Indicators: Reducing the Complexity of First-Time Distillation 集成指令和溶剂极性指示器:降低首次蒸馏的复杂性
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-09 DOI: 10.1021/acs.jchemed.4c00466
Patrick I. T. Thomson, Deborah Cleary
Practical work carries a high cognitive load, particularly when unfamiliar or complex equipment is first introduced. “Integrated Instructions” have been previously used to reduce cognitive load in secondary education practical work by placing instructions within diagrams, reducing the need to integrate disparate sources of information. Here, we use this approach in an undergraduate-level distillation experiment to focus attention, reduce cognitive load, and make space for light “elements of inquiry” learning. The use of a solvatochromic dye as a polarity indicator also adds an unusual visual aspect to distillation, allowing students to easily estimate or verify the composition of fractions.
实践作业具有很高的认知负荷,尤其是在首次引入不熟悉或复杂的设备时。以前,"综合指示 "曾被用于减轻中学教育实践作业中的认知负荷,它将指示放在图表中,减少了整合不同信息源的需要。在这里,我们将这种方法用于本科生水平的蒸馏实验,以集中注意力,减轻认知负荷,并为轻度 "探究要素 "学习留出空间。使用溶解变色染料作为极性指示剂还为蒸馏增加了一个不同寻常的视觉方面,使学生能够轻松地估计或验证分数的组成。
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引用次数: 0
Welcome to 310 Environmental Working Group! A Group Project That Places Students in the Role of Consultants Helping Businesses Choose the Most Climate Friendly Fluorinated Gas 欢迎来到 310 环境工作组!一个让学生扮演顾问角色的小组项目,帮助企业选择对气候最友好的含氟气体
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-06 DOI: 10.1021/acs.jchemed.4c00479
Jessica C. D’eon, Sivani Baskaran, Jennifer A. Faust, Mima Staikova, Cora J. Young
The Montreal Protocol is an international treaty that controls substances that deplete the ozone layer. Through the control of halogenated gases, it has been one of the most successful climate legislations to date. This success is driven by the interplay between chemical regulation and smart chemical design, demonstrating the positive impact chemistry can have on the world. This Article describes a group project that includes four assignments, a group presentation, and a writing task where students take on the role of consultants to assess the environmental friendliness of two fluorinated gases. Through the assignments students determine the global warming potential of two chemicals and pair this assessment with an evaluation of their potential to produce persistent products, such as trifluoroacetic acid, via atmospheric oxidation. Students worked together to take these, sometimes conflicting, pieces of evidence to make a final recommendation to their client as to the most “environmentally friendly” option in a mock Board of Directors meeting and then individually through a written recommendation. The project effectively addressed the learning goals of a third-year environmental chemistry class and was well received by students as a means of contextualizing the course material and providing students with a clear peer network in the class. This project is an effective application of fundamental chemistry topics (e.g., spectroscopy and the relationship between structure and reactivity) within a real-world context that emphasizes the ability of chemistry to have a positive impact on important environmental issues such as climate.
蒙特利尔议定书》是一项控制消耗臭氧层物质的国际条约。通过控制卤化气体,该议定书成为迄今为止最成功的气候立法之一。这一成功得益于化学法规和智能化学设计之间的相互作用,展示了化学可以对世界产生的积极影响。本文介绍了一个小组项目,包括四次作业、一次小组展示和一次写作任务,学生们在其中扮演顾问的角色,评估两种氟化气体的环境友好性。通过这些作业,学生们确定了两种化学物质的全球变暖潜势,并对其通过大气氧化产生持久性产物(如三氟乙酸)的潜势进行了评估。学生们共同努力,利用这些有时相互矛盾的证据,在模拟董事会会议上向客户提出最 "环保 "方案的最终建议,然后单独提出书面建议。该项目有效地实现了三年级环境化学课的学习目标,受到了学生们的欢迎,因为它是将课程材料情景化的一种手段,并为学生们提供了一个清晰的同学网络。该项目有效地将基础化学主题(如光谱学和结构与反应性之间的关系)应用于现实世界中,强调了化学对气候等重要环境问题产生积极影响的能力。
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引用次数: 0
Laboratory Safety Teams as an Evolving Community of Practice: Exploring the How and Why 实验室安全小组是一个不断发展的实践社区:探索如何和为什么
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-06 DOI: 10.1021/acs.jchemed.4c00702
Monica M. S. Nyansa, Jessica A. Martin, Kali A Miller, Kedmon N. Hungwe
Reports of laboratory damage, personal injury, and death have triggered increasing concern over the academic safety culture and the safety education of those pursuing studies in the chemical sciences. Student-led laboratory safety teams (LSTs) within academic institutions serve as a new and expanding informal, bottom-up approach to improving the academic safety culture and safety education of student researchers. Since 2018, a workshop has been run by the American Chemical Society Division of Chemical Health and Safety to support graduate students in the chemical sciences in establishing and growing LSTs of their own. Here, we examine how LSTs within the different academic institutions have evolved into a community of practice (CoP) through these workshops and why the members have engaged in growing this CoP. We determine the current stage of the LST CoP and what values the members created and experienced through the evaluation of artifacts from 14 workshops conducted from 2018 to 2022, semistructured interviews with student researchers running the workshops, and a guided focus group interview with the three primary student leaders of the workshops. We are sharing this analysis with the chemical education community to provide others with insights into experimental ways to improve the safety education of those pursuing studies in the chemical sciences.
有关实验室损坏、人身伤害和死亡的报道引发了人们对学术安全文化和化学科学研究人员安全教育的日益关注。学术机构内由学生领导的实验室安全团队(LST)是一种新的、不断扩大的非正式、自下而上的方法,用于改善学术安全文化和学生研究人员的安全教育。自 2018 年以来,美国化学学会化学健康与安全分会举办了一个研讨会,以支持化学科学专业的研究生建立和发展自己的 LST。在此,我们将研究不同学术机构内的 LST 如何通过这些研讨会发展成为一个实践社区(CoP),以及成员参与发展这一实践社区的原因。我们通过对 2018 年至 2022 年期间开展的 14 个工作坊的人工制品进行评估、对开展工作坊的学生研究人员进行半结构化访谈,以及对工作坊的三位主要学生领导进行有指导的焦点小组访谈,来确定 LST CoP 目前所处的阶段,以及成员们创造和体验了哪些价值。我们正在与化学教育界分享这一分析,以便为其他人提供洞察力,帮助他们了解改进化学科学研究人员安全教育的实验方法。
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引用次数: 0
Visualizing Symmetry: A Resource for Chemical Education with VMD and SYVA Programs 可视化对称性:使用 VMD 和 SYVA 程序的化学教育资源
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-06 DOI: 10.1021/acs.jchemed.4c00530
Qingyan Zeng, Jinglin Mu
Symmetry, a common occurrence in nature, holds significant importance in the realm of chemistry education. However, students often struggle to visualize the symmetry elements of three-dimensional molecules and identify point groups using traditional textbooks. In order to address this challenge, we integrated SYVA into VMD for accurate determination of molecular point groups. Additionally, we have organized molecular point group materials to serve as an educational resource. The resource currently includes hundreds of unique molecules, with continuous expansion, to effectively demonstrate various symmetry elements within molecules and aid in determining point groups. Expanding on this resource, we have designed an educational activity focused on molecular symmetry. According to student feedback, utilizing VMD to showcase molecular point group files and visually represent molecular symmetry elements is beneficial for students in comprehending related concepts. This resource can serve as a valuable tool for teaching symmetry, offering interactivity, visual appeal, and offline accessibility, allowing for flexible use across different times and locations.
对称是自然界中常见的现象,在化学教育领域具有重要意义。然而,使用传统教科书,学生往往难以直观地理解三维分子的对称元素并识别点群。为了解决这一难题,我们将 SYVA 集成到 VMD 中,以准确确定分子点群。此外,我们还整理了分子点群材料,作为教育资源。该资源目前包括数百个独特的分子,并在不断扩展,以有效展示分子中的各种对称元素,帮助确定点群。在此资源的基础上,我们设计了一个以分子对称性为重点的教育活动。根据学生的反馈,利用 VMD 展示分子点群文件并直观地表示分子对称元素,有利于学生理解相关概念。该资源可作为对称性教学的重要工具,具有互动性、视觉吸引力和离线可访问性,可在不同时间和地点灵活使用。
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引用次数: 0
A Novel General Chemistry Experiment for Freshmen: Transgenic Soybean Detection Based on Microfluidic Molecular Fluorescence Spectroscopy Analysis 面向高一新生的新型普通化学实验:基于微流控分子荧光光谱分析的转基因大豆检测
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-05 DOI: 10.1021/acs.jchemed.4c00668
Pintao Li, Min Gu, Ghazala Ashraf, Huiwen Xiong, Fei Cun, Xuting Chen, Jilie Kong, Xueen Fang
In this experiment, we present a microfluidic-based molecular fluorescence spectroscopy method for analyzing nucleic acids to identify transgenic soybeans. This method is integrated into a General Chemistry Experiment course tailored for freshmen. The primary goals of this course are to deepen student’s understanding of some important knowledge points of general chemistry, introduce students to experimental techniques at the micro- and nanoscale, help students understand the principles of molecular fluorescence spectroscopy and enzyme reaction kinetics, elucidate the relationship between chemistry and its practical applications, stimulate their interest in chemistry, and provide multidisciplinary perspectives and thinking. Over the period from 2021 to 2023, more than 180 freshmen enrolled in this course, and over 30 universities in China have initiated the advancement of this course. Most students successfully completed the experiment, achieving high completion rate and promising results. Participating students improved their practical skills and the ability to work collaboratively in a laboratory setting, which led to numerous innovative ideas and insights in related areas. Positive feedback from the students confirmed that the predetermined learning objectives were successfully achieved.
在本实验中,我们介绍了一种基于微流体的分子荧光光谱法,用于分析核酸以鉴定转基因大豆。该方法被整合到为大一新生量身定制的普通化学实验课程中。该课程的主要目标是加深学生对普通化学一些重要知识点的理解,向学生介绍微米和纳米尺度的实验技术,帮助学生理解分子荧光光谱学和酶反应动力学的原理,阐明化学与实际应用的关系,激发学生对化学的兴趣,提供多学科的视野和思维。从2021年到2023年,共有180多名大一新生选修了这门课程,全国已有30多所高校启动了这门课程的推进工作。大部分学生顺利完成了实验,取得了较高的完成率和可喜的成果。参加实验的学生提高了实践技能和在实验室环境中协同工作的能力,在相关领域提出了许多创新想法和见解。学生们的积极反馈证实,预定的学习目标已成功实现。
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引用次数: 0
Alligation Alternate: Borrowing a Useful Concept from the Pharmacy Curriculum 配药交替:从药学课程中借用一个有用的概念
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-05 DOI: 10.1021/acs.jchemed.4c00559
Peter A. C. McPherson, Iain G. Jack
Alligation alternate is an arithmetic technique historically used to solve problems involving proportions and mixtures of the same substance in different concentrations. Demonstration of its use is widespread throughout pharmacy education, but this practice does not appear to extend to most chemistry curricula. As a result of interactions between pharmacy and chemistry students, we have trialed the introduction of alligation alternate as a problem solving technique in the first semester of a freshman chemistry course. We show that while other strategies can be used, students favored the newly introduced alligation alternate procedure due to its diagrammatic form and ease of use. The obvious benefits on cognitive load and use of the psychomotor domain make this a useful addition to precollege and early undergraduate chemistry curricula.
配平交替法是一种运算技巧,历来用于解决涉及不同浓度相同物质的比例和混合物的问题。在药学教育中,这种方法的应用非常广泛,但在大多数化学课程中似乎并没有应用。通过药剂学和化学学生之间的互动,我们在高一化学课程的第一学期尝试引入配伍交替作为解决问题的技巧。结果表明,虽然可以使用其他策略,但新引入的配平交替程序因其图解形式和易于使用而受到学生的青睐。这对认知负荷和心理运动领域的使用都有明显的好处,使其成为大学预科和本科早期化学课程的有益补充。
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引用次数: 0
Simple Nanostructured 3D Printed Objects: An Inside-Out View of Block Copolymer Self-Assembly by Fuse Deposition Modeling 简单的纳米结构三维打印物体:通过熔融沉积建模对嵌段共聚物自组装的由内而外的观察
IF 3 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2024-09-04 DOI: 10.1021/acs.jchemed.4c00438
Laurent Rubatat, Alexandre Foucard, Frédéric Léonardi, Julien Maros, Virginie Pellerin
Polymer 3D printing methods are now widely spread in educational strategies, whether for teachers to produce 3D objects, facilitating knowledge transfer, or directly for students to master a unique polymer processing method. Regarding block copolymer (BCP) microphase separation and self-assembly, which occurs in volume and at the nanoscale, they are both challenging to teach in the classroom without adapted materials. The present paper describes a graduate student laboratory project with two objectives: first, to train students on 3D printing and BCP microphase separation; second, to produce a macroscale 3D representation of the inner BCP microphase separation, such as an inside-out demonstration of the nanostructure, which can be used as a comprehensive object. Interestingly, the project covers a large range of polymer processing and characterization methods, raising fundamental discussions between students and educators. In addition, in this paper we demonstrate the feasibility to easily produce two-phase nanostructured 3D printed objects by fuse deposition modeling from BCP filament using exclusively commercially available means.
目前,聚合物三维打印方法已广泛应用于教育策略中,无论是教师制作三维物体、促进知识传授,还是直接让学生掌握一种独特的聚合物加工方法。关于嵌段共聚物(BCP)的微相分离和自组装,它们发生在体积和纳米尺度上,如果没有合适的材料,在课堂上进行教学都具有挑战性。本文介绍了一个研究生实验室项目,该项目有两个目标:第一,对学生进行三维打印和 BCP 微相分离方面的培训;第二,制作 BCP 内部微相分离的宏观三维表现形式,如纳米结构的内向外演示,该演示可用作综合对象。有趣的是,该项目涵盖了大量聚合物加工和表征方法,引发了学生和教育工作者之间的基础性讨论。此外,在本文中,我们还展示了通过熔融沉积建模从 BCP 长丝中利用完全商业化的手段轻松制作两相纳米结构 3D 打印对象的可行性。
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引用次数: 0
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Journal of Chemical Education
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