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IMMUNOLOGICAL AND SOME BIOLOGICAL BIOMARKERS INVESTIGATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS 系统性红斑狼疮患者免疫学及一些生物标志物的研究
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-19
Abdullah A.MOHAMMED, J. Almadhidi, Ahmed Jasim NAWFAL, Ahmed Talib YASSEN
Immunological and some Biological biomarkers have evolved to aid in the diagnosis and assessment of systemic lupus erythematosus (SLE) pathophysiological processes, with the ultimate objective of enhancing disease management. The aim of this study was to investigate the potential biochemical and immunological indicators for SLE diagnosis and assessment of the pathophysiological process. The samples of this study were divided into two groups: thirty-five SLE patients (10 male and 25 female) with ages ranging from 25 to 34, and thirtyfive healthy controls with ages ranging from 25 to 36, and the biomarkers of this current study were included the Antinuclear Antibody (ANA) (IU/ml), Anti-double-stranded DNA (dsDNA) (IU/ml), Antinuclear Antibody (ANA) (IU/ml), Antinuclear Antibody (ANA) (IU/ml), Antinuclear Antibody (ANA) (IU/ml), Antinuclear Antibody (ANA) (IU/ml), Antinuclear Antibody (ANA) (IU/ml), Anti-Cyclic Citrullinated Peptide (IU/ml), Rheumatoid Factor Latex (IU/ml), C-Reactive Protein (CRp) (mg/l), erythrocyte sedimentation rate (ESR) (mm/h) and body weight (kg/ B.W.). The results was showed a significantly higher percentage in discoid rash (21%), malar rash (29%), photosensitivity (19%) anemia (26%), Proteinuria (21%) and Leukopenia (18%) in patients with SLE; hair loss (5%) and nervous system (4%) was none significantly higher; Anti-dsDNA was the most prevalent presenting characteristic in this research (33%), followed by blood urea (13%), hematuria (12 percent), and renal involvement (12%) in all individuals with SLE. Conclusion: All biomarkers and clinical features studied were found to be elevated in patients with SLE, particularly ANA and Anti-dsDNA, which were the most common autoantibodies found in this study, as well as other immunological and some biological markeres. As a result, For SLE, no one biomarker can be sensitive or specific enough
免疫学和一些生物标志物已经发展到帮助诊断和评估系统性红斑狼疮(SLE)的病理生理过程,最终目的是加强疾病管理。本研究的目的是探讨SLE诊断和病理生理过程评估的潜在生化和免疫学指标。本研究的样本分为两组:35例SLE患者(男10例,女25例),年龄25 ~ 34岁,35例健康对照,年龄25 ~ 36岁,本研究生物标志物包括:抗核抗体(ANA) (IU/ml),抗双链DNA (dsDNA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗核抗体(ANA) (IU/ml),抗环瓜氨酸肽(IU/ml)、类风湿因子乳胶(IU/ml)、c反应蛋白(CRp) (mg/l)、红细胞沉降率(ESR) (mm/h)、体重(kg/ B.W.)。结果显示,SLE患者盘状皮疹(21%)、恶性皮疹(29%)、光敏性(19%)、贫血(26%)、蛋白尿(21%)和白细胞减少(18%)的比例明显较高;脱发(5%)和神经系统(4%)无显著升高;在这项研究中,抗dsdna是最普遍的表现特征(33%),其次是血尿素(13%)、血尿(12%)和肾脏受累(12%)。结论:研究的所有生物标志物和临床特征均在SLE患者中升高,特别是本研究中发现的最常见的自身抗体ANA和Anti-dsDNA,以及其他免疫学和一些生物学标志物。因此,对于SLE,没有一种生物标志物能够足够敏感或特异性
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引用次数: 0
THE SIGNIFICANCE OF COMPLETE BLOOD BLOOD COUNT AS LABORATORY DIAGNOSIS IN COVID-19 全血计数在COVID-19实验室诊断中的意义
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-22
Hanaa A. ABDULMEER, Saba A.ALI, Alyaa Isam
The increased global prevalence of COVID-19 has resulted in a significant increase in the occupancy rate of healthcare facilities, resulting in overcrowding in some areas. In this situation, healthcare staff must efficiently assess patients' status and undertake risk stratification, particularly in a triage setting. The complete blood count is a easily available, cost-effective, and time-saving testing procedure that may be useful in supporting those processes. This review examines changes in complete blood count parameters in COVID-19 patients with the goal to identify the most common changes in the parameters and their relationship to illness progression and severity. Anemia, increased red blood cell distribution width, decreased white blood cell count, significant alterations in white blood cell differential count, and thrombocytopenia were all prevalent symptoms in COVID-19 patients. Changes in complete blood count values and their magnitude are thought to provide useful information regarding illness severity and prognosis. Finally, COVID-19 patients have a consistent pattern of abnormalities in complete blood count values that arelinked to illness development, severity, and prognosis. Given the useful information offered by the test, it is envisaged that complete blood count evaluation would play a significant role in COVID-19 management
COVID-19全球流行率的上升导致医疗机构入住率大幅上升,导致一些地区过度拥挤。在这种情况下,卫生保健人员必须有效地评估患者状况并进行风险分层,特别是在分诊设置中。全血细胞计数是一种容易获得、具有成本效益和节省时间的测试程序,可能有助于支持这些过程。本综述研究了COVID-19患者全血细胞计数参数的变化,目的是确定参数中最常见的变化及其与疾病进展和严重程度的关系。贫血、红细胞分布宽度增加、白细胞计数下降、白细胞差异计数明显改变和血小板减少均为COVID-19患者的常见症状。全血细胞计数值的变化及其大小被认为可以提供有关疾病严重程度和预后的有用信息。最后,COVID-19患者的全血细胞计数值具有一致的异常模式,这与疾病发展、严重程度和预后有关。鉴于该检测提供的有用信息,预计全血细胞计数评估将在COVID-19管理中发挥重要作用
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引用次数: 0
THE IMPACT OF MARINE TRANSGRESSION IN THE MARSHES OF SOUTHERN IRAQ 海侵对伊拉克南部沼泽的影响
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-15
Bushra Majeed ISSA
The marshes in southern Iraq are one of the most interesting phenomena to study because of their unique environment. Therefore, this region has received a lot of attention in various studies. It is known about the environment of the marshes that it represents a fresh water environment where it is supplied with river water. Therefore, it would be natural for the sediments to reflect that environment, especially in the surface areas of it. However, the location of the marshes in the southern part of Mesopotamia, which was affected by changes in the sea water level during the Holocene period, may raise interest to know the environmental status of the marshes during that period. To find out, three sites were chosen in the marshes of northern Basra province to represent the southern part of Iraq, where the depths of the samples varied between surface and subsurface samples, reaching a depth of three meters. The samples were subjected to grain size analysis in order to know the nature of the sediments and the extent of their differences or similarities through the depths, as well as the diagnosis of the shells present in them to define the environment in them at the time while they were following the same environment or there was a change in it with the varying depths. The study showed the dominance of silt deposits in the study area clearly over other types of sediments, in addition to the variation in the sources of those deposits. While the shells, which belong to different types of fauna, revealed the presence of the marine influence in addition to the well-known riverine influence in the region, which confirms the arrival of the impact of the change in the level of marine waters during the Holocene period to the marsh areas in southern Iraq
伊拉克南部的沼泽由于其独特的环境是最有趣的研究现象之一。因此,这一区域在各种研究中受到了很大的关注。众所周知,沼泽的环境代表着淡水环境,它是由河水供应的。因此,沉积物自然会反映该环境,特别是在其表面区域。然而,全新世时期受海平面变化影响的美索不达米亚南部沼泽的位置,可能会引起人们对该时期沼泽环境状况的兴趣。为了找到答案,在巴士拉省北部的沼泽中选择了三个地点来代表伊拉克南部,在那里,样本的深度在地表和地下样本之间变化,深度达到3米。对样品进行粒度分析,以了解沉积物的性质及其在深度上的差异或相似程度,以及对其中存在的贝壳进行诊断,以确定它们在相同环境下或随着深度的变化而变化的当时环境。研究表明,研究区粉砂质沉积物明显优于其他类型的沉积物,此外,这些沉积物的来源也有所不同。而这些属于不同动物群类型的贝壳显示,除了该地区众所周知的河流影响外,还存在海洋影响,这证实了全新世期间海水水位变化对伊拉克南部沼泽地区的影响
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引用次数: 0
GENOTYPING AND SEROPREVALENCE OF TOXOPLASMA GONDII IN ABORTION WITH ELEVATION OF INTERLEUKIN-6 LEVEL 白细胞介素-6水平升高对流产患者刚地弓形虫基因分型及血清流行的影响
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-12
Aya R. Abduwahhab ALHEANY
Toxoplasmosis is a harmful microorganism that resides inside the cells of the host and produces serious symptoms such as abortion. A total of (48) blood samples were taken from aborted women in this study, with (40) healthy persons serving as a control group. Between the 15th of January and the 30th of September 2021, the patients were treated at Al-Karkh Maternity Hospital. The infection rate was highest in the age range (18-25) years for both the infected women and the control group, according to the findings. Among aborted mothers with Toxoplasmosis, the IgG antibody positivity rate was 40 percent higher than the IgM antibody positivity rate, while the negative rate was 8 percent (16.6 percent ). When compared to healthy persons, there was a considerable increase in the frequencies of positive AntiToxoplasmosis IgM antibody (69.8%) and IL-6 (75%) when compared to healthy individuals. IL-6 had a greater prevalence of 36 (66.7%) than IgM (30%). (73.4 percent ). The ROC test was utilized to evaluate those two parameters. The fragment 96bp of the B1 gene of the DNA isolated was inflated using nested PCR test amplification. Ordinary PCR was performed to amplify the IL-6 gene in 431 bp of isolated DNA
弓形虫病是一种寄生在宿主细胞内的有害微生物,会产生严重的症状,如流产。本研究共采集了48例流产妇女的血液样本,并以40例健康人作为对照组。2021年1月15日至9月30日期间,患者在Al-Karkh妇产医院接受治疗。根据研究结果,受感染妇女和对照组的感染率在18-25岁年龄段最高。在感染弓形虫病的流产母亲中,IgG抗体阳性率比IgM抗体阳性率高40%,阴性率为8%(16.6%)。与健康人相比,抗弓形虫IgM抗体阳性(69.8%)和IL-6阳性(75%)的频率显著增加。IL-6的患病率36(66.7%)高于IgM(30%)。(73.4%)。采用ROC检验对这两个参数进行评价。用巢式PCR扩增扩增分离DNA的B1基因96bp片段。用普通PCR扩增IL-6基因,扩增量为431 bp
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引用次数: 0
MOLECULAR CHARACTERIZATION OF UNKNOWN FUNGAL ISOLATES FROM SOIL SAMPLES IN GARDENS OF MUSTANSIRIYAH UNIVERSITY /BAGHDAD CITY-IRAQ 伊拉克巴格达市穆斯坦西里耶大学花园土壤样品中未知真菌分离株的分子特征
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-4
Noor T. Hamdan
The botanical gardens of Al-Mustansiriyah University are very rich, containing a wide variety of microorganisms which have not been recognised before. As a result, there are seven fungal isolates were molecular identified via Internal Transcribed Spacer (ITS) regions from these gardens in spring 2021 and including as Fusarim boothii, Talaromyces sp, Gliocladium viride, Sordariomycetes sp, and three of Fusarium oxysporium. This document is done to evaluate the molecular characterization of some unknown fungal isolates from soil samples in gardens of Mustansiriyah University /Baghdad city-Iraq
Al-Mustansiriyah大学的植物园非常丰富,包含各种各样以前未被认识到的微生物。结果,在2021年春季,通过内部转录间隔区(ITS)从这些花园中分离出7株真菌,包括Fusarim boothii、Talaromyces sp、Gliocladium viride、Sordariomycetes sp和3株镰刀菌(Fusarium oxysporium)。本文对伊拉克巴格达市穆斯坦西里耶大学花园土壤样品中一些未知真菌分离株的分子特性进行了评价
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引用次数: 0
RELATIONSHIP OF ESSENTIALLY SEMISMALL QUASI-DEDEKIND MODULES WITH SCALAR AND MULTIPLICATION MODULES 本质半小拟dedekind模与标量模和乘法模的关系
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-24
Uhood Saadi Abdulkarem, Mukdad Qaess HUSSAIN
Let R be a ring with 1 and W is a left Module over R. A Submodule D of an R-Module W is small in W(D ≪ W) if whenever a Submodule V of W s.t W = D + V then V = W. A proper Submodule Y of an R-Module W is semismall in W(Y ≪_S W) if Y = 0 or Y/F ≪ W/F ∀ nonzero Submodules F of Y. A Submodule U of an R-Module E is essentially semismall(U ≪es E), if for every non zero semismall Submodule V of E, V∩U ≠ 0. An R-Module E is essentially semismall quasi-Dedekind(ESSQD) if Hom(E/W, E) = 0 ∀ W ≪es E. A ring R is ESSQD if R is an ESSQD R-Module. An R-Module E is a scalar R-Module if, ∀ , ∃ s.t V(e) = ze ∀ . In this paper, we study the relationship between ESSQD Modules with scalar and multiplication Modules. We show that if E is scalar semismall quasi-prime R-Module. Then E is an ESSQD R-Module, we show that if E is faithful multiplication R-Module, thus E is an essentially semismall prime R-Module iff R is an ESSQD ring
让R是一个环1和W是一个左模块/ R R模的子模块D W W (D≪W)如果小每当子模块V (W s.t W = D + V V = W·R模的一个适当的子模块Y W semismall在W (Y≪_ W)如果Y = 0或Y / F≪W / Y∀非零子F R模的子模块U E是semismall (U≪es E),如果对每一个非零semismall子模块E V, V∩U≠0。如果hm (E/W, E) = 0∀W≪es E,则R- module E本质上是半小型准dedekind (ESSQD);如果R是ESSQD R- module,则R环是ESSQD。若∀,∃s.t V(E) = ze,则r模E是标量r模。本文研究了ESSQD模与标量模和乘法模之间的关系。我们证明了如果E是标量半小拟素数r模。则E是ESSQD的R模,证明了如果E是忠实的乘法R模,则如果R是ESSQD环,则E是本质上的半小素数R模
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引用次数: 0
EVALUATION THE NEEDS OF PLAY SPACES IN KINDERGARTEN FROM A BIOPHILIC PERSPECTIVE (MOSUL AS A CASE STUDY) 从亲生物的角度评估幼儿园游戏空间的需求(以摩苏尔为例)
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-5
Maysaa Moffeq ALOBAIDI
Childhood represents one of the important stages in human life, in which the child's abilities develop and his talents open, and the child can influence, direct and form both physically and mentally. Playspaces are the best place in which the child can meet the needs of his body and psyche, so it has become necessary to take care of this space, which represents a good environment for the development of the child's potential and improving his social behavior, and recent studies have proven that the interaction of the child with nature in this type of space is one of the positive aspects That can contribute to the child's development, health and behavior, hence the importance of researching the needs of indoor and outdoor play spaces. In kindergarten buildings, which are the category of children aged (4-5) years, the research aims to evaluate the needs of indoor and outdoor play spaces for kindergartens from A Biophilic perspective, after surveying the opinions of mothers about the needs of their children in those places, which contributes to promoting Child health and behavior, and evaluation of the reality of indoor and outdoor play spaces in kindergartens in Mosul from a biophilic perspective, which achieves interaction and harmony with the environment and contributes to improving his health, behavior, and psyche
童年是人的一生中最重要的阶段之一,在这个阶段,孩子的能力得到发展,他的才能得到发挥,孩子可以在身体和精神上影响、指导和形成。游戏空间是儿童能够满足其身体和心理需求的最佳场所,因此照顾好这个空间就变得很有必要,它代表了一个开发儿童潜能和改善其社会行为的良好环境,最近的研究证明,儿童在这种类型的空间中与自然的互动是一个积极的方面,可以有助于儿童的发展,健康和行为。因此,研究室内和室外游戏空间的需求非常重要。在幼儿园建筑(4-5岁)儿童类别中,研究旨在通过调查母亲对这些地方的孩子需求的意见(这有助于促进儿童健康和行为),从亲生物的角度评估幼儿园室内外游戏空间的需求,并从亲生物的角度评估摩苏尔幼儿园室内外游戏空间的现实性。实现与环境的互动和和谐,有助于改善他的健康,行为和心理
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引用次数: 0
VISIBLE QUANTITATIVE ASSAY OF PEPCID IN PHARMACEUTICAL DOSAGE FORMS VIA SAFRANIN REAGENT 用红花红试剂进行药物剂型中肽的可见定量分析
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-13
Shahla A. YOUNIS, Basima A. A. SALEEM, Ali Khudheyer OBAYES, Ghassan Q. ISMAIL
Due to the medical importance of Pepcid, a spectrophotometric method had been suggested for the determination of Pepcid in its pure form as well as in some of its pharmaceutical preparations. The proposed method relies on two important steps; the first one, is the oxidation-reduction reaction between Pepcid and an amount of cerium IV (oxidizing agent) in presence of acidic medium, followed by the second step that occurs between cerium (III) with safranin, at the selected wavelength 514 nm. The proposed method obeyed Beer's law within the range (2-40) µg.mL-1, with good sensitivity relative to the molar absorption coefficient value 3.21×104 l.mol-1.cm-1 and the Sandal value equal to 0.00105μg.cm-2. The proposed method has been successfully applied to quantify Pepcid in pure form and its pharmaceutical preparations
由于消化酶在医学上的重要性,已经提出了一种分光光度法来测定其纯形式及其一些药物制剂。所提出的方法依赖于两个重要步骤;第一步是在酸性介质存在下,Pepcid与一定量的cerium IV(氧化剂)发生氧化还原反应,第二步是cerium (III)与safranin在选定波长514 nm处发生氧化还原反应。该方法在(2 ~ 40)µg范围内符合比尔定律。mL-1,相对于摩尔吸收系数值3.21×104 l.mol-1具有良好的灵敏度。Sandal值为0.00105μg.cm-2。该方法已成功地应用于Pepcid的纯形式及其药物制剂的定量
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引用次数: 0
SYNTHESIS ,CHARACTERIZATION AND BIOLOGICAL ACTIVITY STUDY OF SOME HETEROCYCLIC COMPOUNDS 杂环类化合物的合成、表征及生物活性研究
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-18
Enaam Fadil MOUSA, Ibtissam Khalifa JASSIM
Heterocycles are an important class of organic compounds because of their applications in medicines and industrial fields. Therefore our study included preparation of these compound such as oxazepine and quinazoline rings, which were prepared through two steps: The first step included the reaction of the Schiff bases derived from sulfamethaxazole (1-4) with each of phthalic anhydride and 3- nitrophthalic anhydride for the preparation of oxazepines (5-12) .While the second step included the preparation of quinazoline compounds (13-16) from the reaction of Schiff bases (1-4) with anthranilic acid using dry benzene as a medium and solvent for the reaction. All prepared compounds were characterized by using infrared,proton- nuclear magnetic resonance, mass techniques and melting points, and their purity was determined by thin layer chromatography technique also screened the biological activity of some of these prepared compounds by using two types of bacteria Gram-positive and negative . The results showed that these compounds have a good inhibition against these organisms
杂环化合物是一类重要的有机化合物,在医药和工业领域有着广泛的应用。因此,我们的研究包括了这些化合物的制备,如恶氮平和喹唑啉环,通过两个步骤制备:第一步是由磺胺甲恶唑(1-4)衍生的希夫碱与邻苯二甲酸酐和3-硝基邻苯二甲酸酐分别反应制得恶氮平(5-12),第二步是由希夫碱(1-4)与邻苯苯甲酸反应制得喹唑啉化合物(13-16),反应采用干苯作为介质和溶剂。利用红外光谱、质子核磁共振、质量技术和熔点对化合物进行了表征,并利用薄层色谱技术对化合物纯度进行了测定,同时利用革兰氏阳性和阴性两种细菌对部分化合物的生物活性进行了筛选。结果表明,这些化合物对这些微生物具有良好的抑制作用
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引用次数: 0
SPECTROSCOPIC ANALYSIS OF MAGNESIUM OXIDE PLASMA PRODUCED BY LASER 激光产生氧化镁等离子体的光谱分析
Pub Date : 2022-03-01 DOI: 10.47832/minarcongress4-10
Ghaith H. JIHAD, Safaa A. HAMEED, Kadhim A. AADIM
My proceding prepared magnesium oxide nanoparticles using pulsed laser deposition in an air environment. At which deposition of pure Mg and MgO powders prepared as bult with thickness 1 cm under pressure 6 ton and Using a Q-switched Nd: YAG laser with a wavelength of 9nsec of 1064 nm, the influence of energy laser on size material of particle as well as optical characteristics and surface morphology as a result of laser pulses were examined.The absorption spectra of MgO exhibited a redshift in UV-visible measurements. X-ray diffraction (XRD) investigation showed the Mg metal powder percentage purities. The properties of plasma are studied using optical emission spectroscopy (OES).
我的程序在空气环境中使用脉冲激光沉积制备氧化镁纳米颗粒。利用波长为9nsec (1064 nm)的调q Nd: YAG激光器,在6吨压力下沉积厚度为1 cm的纯Mg和MgO粉末,研究了能量激光对颗粒材料尺寸的影响以及激光脉冲对光学特性和表面形貌的影响。MgO的吸收光谱在紫外可见测量中表现出红移。x射线衍射(XRD)研究表明了金属镁粉末的百分纯度。利用光学发射光谱(OES)研究了等离子体的性质。
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引用次数: 0
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