Aprildo Christofel Dapot Tua Parulian Gultom, Ketut Sumerjana, I. K. Darmayuda, N. Ardini
Purpose: The purpose of this research is to find out the role of Pregina Art & Showbiz, e.g. the pre-production, production, and post-production processes, as well as the obstacles that occurred during the opening of the 14th Denpasar Festival on 10 December 2021 at Alaya Dharma Negara building, Denpasar. Research methods: the qualitative method used during this activity covers participant-observation, interview, and documentation. Results and discussion: Having participated at the activity, the writers knew what Pregina Art & Showbiz Art's role was. Pregina Art & Showbiz became the Event Organizer for this event and made a live stream. Implication: There are a special knowledge and skill on how to lead an event and how to market and sell it directly to clients via social media.
目的:本研究的目的是找出Pregina Art & Showbiz的作用，例如前期制作，制作和后期制作过程，以及2021年12月10日在登巴萨Alaya Dharma Negara大楼举行的第14届登巴萨节开幕式期间发生的障碍。研究方法:本次活动采用的定性方法包括参与者观察、访谈和文献记录。结果与讨论:通过参与活动，作者了解了Pregina Art & Showbiz Art的角色。Pregina Art & Showbiz成为本次活动的活动组织者，并制作了直播。暗示:有一种特殊的知识和技能，关于如何领导一个事件，以及如何通过社交媒体直接向客户营销和销售它。
{"title":"Pregina Art & Showbiz Participation in the 14th Denpasar Festival Opening Ceremony","authors":"Aprildo Christofel Dapot Tua Parulian Gultom, Ketut Sumerjana, I. K. Darmayuda, N. Ardini","doi":"10.51172/jbmb.v3i3.236","DOIUrl":"https://doi.org/10.51172/jbmb.v3i3.236","url":null,"abstract":"Purpose: The purpose of this research is to find out the role of Pregina Art & Showbiz, e.g. the pre-production, production, and post-production processes, as well as the obstacles that occurred during the opening of the 14th Denpasar Festival on 10 December 2021 at Alaya Dharma Negara building, Denpasar. Research methods: the qualitative method used during this activity covers participant-observation, interview, and documentation. Results and discussion: Having participated at the activity, the writers knew what Pregina Art & Showbiz Art's role was. Pregina Art & Showbiz became the Event Organizer for this event and made a live stream. Implication: There are a special knowledge and skill on how to lead an event and how to market and sell it directly to clients via social media.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83585243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Solihin, Ida Ayu Ketut Sumawidari, I. P. Budiarta, I. G. M. Wendri, I. N. Kanca
Tujuan: Studi ini bertujuan membahas bentuk kerukunan Umat Islam-Hindu di Kampung Loloan, Jembrana, Bali, dan pendidikan multikultural dalam kehidupan masyarakat setempat. Metode penelitian: Data penelitian diperoleh melalui kajian pustaka, observasi dan wawancara dengan pemerhati budaya Bali dan tokoh masyarakat Kampung Loloan. Hasil dan pembahasan: Bentuk kerukunan itu antara lain tercermin dalam kuatnya tradisi menyamebraya yang diwijudkan dalam bentuk silaturahmi, saling ngejot, pemakaian bahasa Loloan atau bahasa Melayu-Bali, serta kerjasama dalam pangan kehidupan sosial dan ekonomi. Kerukunan dan kehidupan multikultural dalam kehidupan masyarakat Kampung Loloan diperkuat dengan adanya model pendidilkan multikultural yang meliputi lima dimensi: menyadarkan generasi penerus tentang arti peting multikulturalisme; meningkatkan pengetahuan tentang keragaman budaya; menanamkan sikap toleransi, menumbuhkan sikap solidaritas (kerjasama) antar-umat; dan menanamkan sikap cinta damai. Implikasi: Proses sosialisasi dan enkulturasi nilai-nilai kerukunan kepada generasi berlangsung secara formal (di sekolah dasar dan menengah), semangat menyamebraya juga dipraktikkan langsung dakan kehidupan sehari-hari masyatakat Kampung Loloan, Jembrana.
{"title":"Pendidikan Multikultural di Kampung Loloan, Jembrana","authors":"Solihin, Ida Ayu Ketut Sumawidari, I. P. Budiarta, I. G. M. Wendri, I. N. Kanca","doi":"10.51172/jbmb.v3i3.238","DOIUrl":"https://doi.org/10.51172/jbmb.v3i3.238","url":null,"abstract":"Tujuan: Studi ini bertujuan membahas bentuk kerukunan Umat Islam-Hindu di Kampung Loloan, Jembrana, Bali, dan pendidikan multikultural dalam kehidupan masyarakat setempat. \u0000Metode penelitian: Data penelitian diperoleh melalui kajian pustaka, observasi dan wawancara dengan pemerhati budaya Bali dan tokoh masyarakat Kampung Loloan. \u0000Hasil dan pembahasan: Bentuk kerukunan itu antara lain tercermin dalam kuatnya tradisi menyamebraya yang diwijudkan dalam bentuk silaturahmi, saling ngejot, pemakaian bahasa Loloan atau bahasa Melayu-Bali, serta kerjasama dalam pangan kehidupan sosial dan ekonomi. Kerukunan dan kehidupan multikultural dalam kehidupan masyarakat Kampung Loloan diperkuat dengan adanya model pendidilkan multikultural yang meliputi lima dimensi: menyadarkan generasi penerus tentang arti peting multikulturalisme; meningkatkan pengetahuan tentang keragaman budaya; menanamkan sikap toleransi, menumbuhkan sikap solidaritas (kerjasama) antar-umat; dan menanamkan sikap cinta damai. Implikasi: Proses sosialisasi dan enkulturasi nilai-nilai kerukunan kepada generasi berlangsung secara formal (di sekolah dasar dan menengah), semangat menyamebraya juga dipraktikkan langsung dakan kehidupan sehari-hari masyatakat Kampung Loloan, Jembrana.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89798079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Indonesia will be free of TB (Tuberculosis) in 2050, and elimination will begin in 2030. TB cases are still high in Bandar Lampung City, so efforts are needed to solve the problem. Mapping of TB cases using a Geographic Information Spatial (GIS) approach was performed in this study to evaluate the spreading patterns of TB patients so that policies can be taken to deal with TB cases in an epidemiological manner. Methods: The research was conducted in 31 public health centers in Bandar Lampung City. The number of TB patients in this study was 879 people. Making maps for visualizing the spread of TB patients using Archgis software, data were analyzed with Geoda and Moran's Index to see the spatial relationship between variables. Results: The spatial analysis using Geoda found a spatial relationship between TB patients and population density (p=0.00079) and the distance between the TB patient's house and the health center (p=0.00000). However, there was a significant relationship between the underprivileged group (p=0.21682) and topography (p= 0.29139). The Z score for the 4 variables is quite large and >Z0.95, so the distribution pattern of TB patients is stated to be clustered (cluster). Conclusion: Based on the TB patients mapping and the spatial analysis, it is known that the distribution pattern of TB patients in Bandar Lampung City forms a clusters pattern, and there is an autocorrelation relationship between population density, underprivileged groups, height and distance from the TB patient's house to the health center.
{"title":"Distribution pattern and spatial analysis of factors for tuberculosis (TB) cases in Bandar Lampung City in 2022","authors":"Maria Tuntun, S. Aminah, Yusrizal CH","doi":"10.15562/bmj.v12i1.3918","DOIUrl":"https://doi.org/10.15562/bmj.v12i1.3918","url":null,"abstract":"Background: Indonesia will be free of TB (Tuberculosis) in 2050, and elimination will begin in 2030. TB cases are still high in Bandar Lampung City, so efforts are needed to solve the problem. Mapping of TB cases using a Geographic Information Spatial (GIS) approach was performed in this study to evaluate the spreading patterns of TB patients so that policies can be taken to deal with TB cases in an epidemiological manner.\u0000Methods: The research was conducted in 31 public health centers in Bandar Lampung City. The number of TB patients in this study was 879 people. Making maps for visualizing the spread of TB patients using Archgis software, data were analyzed with Geoda and Moran's Index to see the spatial relationship between variables.\u0000Results: The spatial analysis using Geoda found a spatial relationship between TB patients and population density (p=0.00079) and the distance between the TB patient's house and the health center (p=0.00000). However, there was a significant relationship between the underprivileged group (p=0.21682) and topography (p= 0.29139). The Z score for the 4 variables is quite large and >Z0.95, so the distribution pattern of TB patients is stated to be clustered (cluster).\u0000Conclusion: Based on the TB patients mapping and the spatial analysis, it is known that the distribution pattern of TB patients in Bandar Lampung City forms a clusters pattern, and there is an autocorrelation relationship between population density, underprivileged groups, height and distance from the TB patient's house to the health center.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44744815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I Gusti Bagus Rai Utama, I. Junaedi, Pancasila ' Putri, I. M. Sumartana
Tujuan: Penelitian ini dilakukan untuk menganalisis popularitas empat destinasi wisata pulau di dunia yaitu Phuket, Bali, Hawaii, dan Langkawi. Metode penelitian: Penelitian ini menggunakan alat analisis statistik deskriptif dengan bantuan Google Trends untuk menentukan popularitas empat destinasi pulau tersebut. Hasil dan pembahasan: Analisis menunjukkan bahwa sejak awal tahun 2000 hingga akhir tahun 2021, destinasi Phuket sangat populer bagi wisatawan yang berasal dari Thailand sendiri, Russia, Turkey, Hong Kong, dan Singapore. Bali sangat populer di kalangan wisatawan Indonesia sendiri, Netherlands, India, Australia, dan Belgium. Hawaii sangat populer di kalangan wisatawan dari United States sendiri, Japan, Canada, Brazil, dan South Korea. Langkawi sangat populer di kalangan wisatawan yang berasal dari Malaysia sendiri, Singapore, Pakistan, Hong Kong, dan Egypt. Implikasi: Destinasi wisata yang paling populer adalah Hawaii, kemudian Bali, lalu Phuket, dan yang terakhir adalah Langkawi. Bali menduduki posisi kedua atau setelah Hawaii.
{"title":"Popularitas Empat Destinasi Wisata Pulau Terbaik Dunia Menggunakan Google Trends","authors":"I Gusti Bagus Rai Utama, I. Junaedi, Pancasila ' Putri, I. M. Sumartana","doi":"10.51172/jbmb.v3i3.229","DOIUrl":"https://doi.org/10.51172/jbmb.v3i3.229","url":null,"abstract":"Tujuan: Penelitian ini dilakukan untuk menganalisis popularitas empat destinasi wisata pulau di dunia yaitu Phuket, Bali, Hawaii, dan Langkawi. \u0000Metode penelitian: Penelitian ini menggunakan alat analisis statistik deskriptif dengan bantuan Google Trends untuk menentukan popularitas empat destinasi pulau tersebut. \u0000Hasil dan pembahasan: Analisis menunjukkan bahwa sejak awal tahun 2000 hingga akhir tahun 2021, destinasi Phuket sangat populer bagi wisatawan yang berasal dari Thailand sendiri, Russia, Turkey, Hong Kong, dan Singapore. Bali sangat populer di kalangan wisatawan Indonesia sendiri, Netherlands, India, Australia, dan Belgium. Hawaii sangat populer di kalangan wisatawan dari United States sendiri, Japan, Canada, Brazil, dan South Korea. Langkawi sangat populer di kalangan wisatawan yang berasal dari Malaysia sendiri, Singapore, Pakistan, Hong Kong, dan Egypt. \u0000Implikasi: Destinasi wisata yang paling populer adalah Hawaii, kemudian Bali, lalu Phuket, dan yang terakhir adalah Langkawi. Bali menduduki posisi kedua atau setelah Hawaii.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74458263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anak Agung Bagus Harjunanthara, I. K. Sariada, Ida Ayu Wimba Ruspawati
Purpose: This paper aims to discuss a new dance creation entitled "Nataka Bhinna" which comes from a cross-gender phenomenon. Research method: Using Balinese gamelan and MIDI (musical instrument digital interface), the dance is presented with stage choreography at Museum Puri Lukisan Ubud. Its analysis uses imagination theory, aesthetic theory, and semiotic theory. Results and discussion: The movement motifs used in "Nataka Bhinna" dance work using ngagem are created to follow the theme raised in the arrangement of the work. The tandang movement was developed without eliminating the grip of the away movement itself. The tangkep movement is developed according to the expression and emphasizes the characters used. Implication: This dance has a message related to how human should humanize humans.
{"title":"“Nataka Binna”: Karya Tari Fenomena Lintas-Gender dan Penolakan Perundungan","authors":"Anak Agung Bagus Harjunanthara, I. K. Sariada, Ida Ayu Wimba Ruspawati","doi":"10.51172/jbmb.v3i3.237","DOIUrl":"https://doi.org/10.51172/jbmb.v3i3.237","url":null,"abstract":"Purpose: This paper aims to discuss a new dance creation entitled \"Nataka Bhinna\" which comes from a cross-gender phenomenon. \u0000Research method: Using Balinese gamelan and MIDI (musical instrument digital interface), the dance is presented with stage choreography at Museum Puri Lukisan Ubud. Its analysis uses imagination theory, aesthetic theory, and semiotic theory. \u0000Results and discussion: The movement motifs used in \"Nataka Bhinna\" dance work using ngagem are created to follow the theme raised in the arrangement of the work. The tandang movement was developed without eliminating the grip of the away movement itself. The tangkep movement is developed according to the expression and emphasizes the characters used. \u0000Implication: This dance has a message related to how human should humanize humans.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87510306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronald Winardi Kartika, Veronica Sidharta, Tena Djuartina, Ignatio Rika, Cynthia Retna Sartika, Kris Hemawan Timotius
Umbilical Cord Mesenchyme stem cell (UC-MSCs) /secretome has been applied for treating several diseases, such as cardio-protection and diabetes. Secretome-derived paracrine modulating effects of various growth factors, cytokines, chemokines, angiogenic factors, and exosomes are used in aging therapy. In recent clinical trials on sarcopenia therapy such as pharmaceutical interventions, nutrition, and physical exercise are reported to be effective strategies to reduce sarcopenia. The pathomechanism of the secretome in the treatment of sarcopenia is unclear. This study looked into how secretome might affect myostatin, a biomarker of sarcopenia, at the molecular level. Myostatin, a member of the TGF-family, significantly increases muscle growth when it is absent while suppressing muscle growth when it is present. A bioactive substance called secretome is secreted by MSCs in conditioned conditions. It is rich in growth factors and cytokines, which are crucial for speeding up tissue regeneration. Secretome intervention is a promising approach for treating sarcopenia as showed by its ability to prevent muscle loss and to improve molecular biomarkers.
{"title":"Role of myostatin protein in sarcopenia (aging muscle) after conditioned medium umbilical cord mesenchymal stem cells (secretome) therapy: mini review","authors":"Ronald Winardi Kartika, Veronica Sidharta, Tena Djuartina, Ignatio Rika, Cynthia Retna Sartika, Kris Hemawan Timotius","doi":"10.15562/bmj.v12i1.3790","DOIUrl":"https://doi.org/10.15562/bmj.v12i1.3790","url":null,"abstract":"Umbilical Cord Mesenchyme stem cell (UC-MSCs) /secretome has been applied for treating several diseases, such as cardio-protection and diabetes. Secretome-derived paracrine modulating effects of various growth factors, cytokines, chemokines, angiogenic factors, and exosomes are used in aging therapy. In recent clinical trials on sarcopenia therapy such as pharmaceutical interventions, nutrition, and physical exercise are reported to be effective strategies to reduce sarcopenia.\u0000The pathomechanism of the secretome in the treatment of sarcopenia is unclear. This study looked into how secretome might affect myostatin, a biomarker of sarcopenia, at the molecular level. Myostatin, a member of the TGF-family, significantly increases muscle growth when it is absent while suppressing muscle growth when it is present. A bioactive substance called secretome is secreted by MSCs in conditioned conditions. It is rich in growth factors and cytokines, which are crucial for speeding up tissue regeneration. Secretome intervention is a promising approach for treating sarcopenia as showed by its ability to prevent muscle loss and to improve molecular biomarkers.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45741602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Sarcopenia is a negative predictor of colorectal cancer outcomes, while colorectal cancer is at risk of developing malnutrition due to the disease process. This study aims to determine the relationship between sarcopenia and nutritional status and analyze the effect of sarcopenia on the outcome of rectal cancer patients. Method: A cross-sectional study was conducted on colorectal cancer patients of Javanese ethnicity who performed preoperative abdominal CT scans at dr. Sardjito Hospital in Yogyakarta between June and December 2019. Sarcopenia is based on measuring muscle mass index at the third lumbar vertebra level <36.0 cm2/m2 for men and < 29.0 cm2/m2 for women. Statistical analyzes using SPSS version 20 for Windows were performed to find out the correlation. Results: Of 46 patients, 56.5% were male and 43.5% female, with a mean age of 53.57. Sarcopenia was found in 47.8% of patients, mostly in women than men (63.6% vs. 36.4% p=0.019). Underweight was mostly found in the sarcopenia group compared to non-sarcopenia (59.1% vs. 20.8% p=0.019). The sarcopenia group has longer LOS than non-sarcopenia (14.73±13.474 vs. 12.29 ±4.165; p=0.404). The mortality of the sarcopenia group was 1.56 times higher compared to the non-sarcopenia (57.1% vs. 42.9%; OR=1.56; 95%CI=0.307-7.890; p=0.964). Haemoglobin, albumin, total protein, CEA, histopathology, tumor location and procedure were not significantly correlated to sarcopenia. Conclusion: Underweight nutritional status and females are correlated with sarcopenia. Sarcopenia tends to be treated longer and has higher mortality than non-sarcopenia.
背景:骨骼肌减少症是结直肠癌预后的负面预测因子，而结直肠癌由于疾病过程而存在发展为营养不良的风险。本研究旨在确定肌少症与营养状况的关系，分析肌少症对直肠癌患者转归的影响。方法:对2019年6月至12月在日惹dr. Sardjito医院进行术前腹部CT扫描的爪哇族结直肠癌患者进行横断面研究。肌肉减少症是基于测量第三腰椎水平的肌肉质量指数，男性<36.0 cm2/m2，女性< 29.0 cm2/m2。采用SPSS version 20 for Windows进行统计分析，找出相关性。结果:46例患者中男性占56.5%，女性占43.5%，平均年龄53.57岁。47.8%的患者出现肌肉减少症，女性多于男性(63.6%比36.4% p=0.019)。与非肌肉减少组相比，肌肉减少组中体重不足的发生率最高(59.1%比20.8% p=0.019)。肌少症组LOS较非肌少症组长(14.73±13.474∶12.29±4.165;p = 0.404)。骨骼肌减少症组的死亡率是非骨骼肌减少症组的1.56倍(57.1%比42.9%;或= 1.56;95%可信区间= 0.307 - -7.890;p = 0.964)。血红蛋白、白蛋白、总蛋白、CEA、组织病理学、肿瘤位置和手术与肌少症无显著相关性。结论:女性体重不足与肌肉减少症相关。与非肌肉减少症相比，肌肉减少症的治疗时间更长，死亡率更高。
{"title":"Sarcopenia as an indicator of nutritional status and outcome predictor for colorectal cancer in Javanese ethnic","authors":"Damianus Hipolitus, A. Handaya, Agus Barmawi","doi":"10.15562/bmj.v12i1.3706","DOIUrl":"https://doi.org/10.15562/bmj.v12i1.3706","url":null,"abstract":"Background: Sarcopenia is a negative predictor of colorectal cancer outcomes, while colorectal cancer is at risk of developing malnutrition due to the disease process. This study aims to determine the relationship between sarcopenia and nutritional status and analyze the effect of sarcopenia on the outcome of rectal cancer patients.\u0000Method: A cross-sectional study was conducted on colorectal cancer patients of Javanese ethnicity who performed preoperative abdominal CT scans at dr. Sardjito Hospital in Yogyakarta between June and December 2019. Sarcopenia is based on measuring muscle mass index at the third lumbar vertebra level <36.0 cm2/m2 for men and < 29.0 cm2/m2 for women. Statistical analyzes using SPSS version 20 for Windows were performed to find out the correlation.\u0000Results: Of 46 patients, 56.5% were male and 43.5% female, with a mean age of 53.57. Sarcopenia was found in 47.8% of patients, mostly in women than men (63.6% vs. 36.4% p=0.019). Underweight was mostly found in the sarcopenia group compared to non-sarcopenia (59.1% vs. 20.8% p=0.019). The sarcopenia group has longer LOS than non-sarcopenia (14.73±13.474 vs. 12.29 ±4.165; p=0.404). The mortality of the sarcopenia group was 1.56 times higher compared to the non-sarcopenia (57.1% vs. 42.9%; OR=1.56; 95%CI=0.307-7.890; p=0.964). Haemoglobin, albumin, total protein, CEA, histopathology, tumor location and procedure were not significantly correlated to sarcopenia.\u0000Conclusion: Underweight nutritional status and females are correlated with sarcopenia. Sarcopenia tends to be treated longer and has higher mortality than non-sarcopenia.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43967635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The use of certain opioids associated differently with the incidence of postoperative delirium (POD). Remifentanil and fentanyl are short-acting opioids widely used in surgery; however, studies assessing their relationship with POD incidence are still limited. This study aimed to determine the association of remifentanil and fentanyl uses with the incidence of POD in elective orthopedic surgery patients. Methods: A cross-sectional study was conducted in Surgical Unit at Dr Soetomo General Academic Hospital in Surabaya, Indonesia from August to September 2022. Patients who underwent elective orthopedic surgery and used remifentanil (n=16) and fentanyl (n=14) as postoperative analgesia were enrolled in the study. Delirium was assessed using Confusion Assessment Method-ICU tool (CAM-ICU). The associations of remifentanil and fentanyl use as well as patients’ characteristics with POD incidence were assessed statistically. Results: Our data found that there was no significant difference between the incidence of POD with the use of remifentanil (p=0.125) in orthopedic surgery patients. The total doses of fentanyl and morphine equivalent (of remifentanil or fentanyl) were associated significantly with the POD incidence (p=0.010 and p=0.002, respectively). Other factors associated with POD incidence were the use of bone cement during the surgery (p=0.034), duration of surgery (p<0.001), and bleeding volume during the surgery (p=0.024). Conclusions: Our study showed high dose of fentanyl, use of bone cement, longer duration of surgery, and high bleeding volume have greater risk of developing POD in orthopedic surgery patients.
{"title":"The effect of intravenous remifentanil and fentanyl postoperative delirium incidence in patients receiving elective orthopedic surgeries","authors":"Hanung Aryana, Dedi Susila, Belindo Wirabuana","doi":"10.15562/bmj.v11i3.3851","DOIUrl":"https://doi.org/10.15562/bmj.v11i3.3851","url":null,"abstract":"Background: The use of certain opioids associated differently with the incidence of postoperative delirium (POD). Remifentanil and fentanyl are short-acting opioids widely used in surgery; however, studies assessing their relationship with POD incidence are still limited. This study aimed to determine the association of remifentanil and fentanyl uses with the incidence of POD in elective orthopedic surgery patients.\u0000Methods: A cross-sectional study was conducted in Surgical Unit at Dr Soetomo General Academic Hospital in Surabaya, Indonesia from August to September 2022. Patients who underwent elective orthopedic surgery and used remifentanil (n=16) and fentanyl (n=14) as postoperative analgesia were enrolled in the study. Delirium was assessed using Confusion Assessment Method-ICU tool (CAM-ICU). The associations of remifentanil and fentanyl use as well as patients’ characteristics with POD incidence were assessed statistically.\u0000Results: Our data found that there was no significant difference between the incidence of POD with the use of remifentanil (p=0.125) in orthopedic surgery patients. The total doses of fentanyl and morphine equivalent (of remifentanil or fentanyl) were associated significantly with the POD incidence (p=0.010 and p=0.002, respectively). Other factors associated with POD incidence were the use of bone cement during the surgery (p=0.034), duration of surgery (p<0.001), and bleeding volume during the surgery (p=0.024).\u0000Conclusions: Our study showed high dose of fentanyl, use of bone cement, longer duration of surgery, and high bleeding volume have greater risk of developing POD in orthopedic surgery patients.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47530912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Atmajaya, Mohammad Satriyo Wibowo, P. Airlangga, Maulydia, Prihatma Kriswidyatomo, Muhtarum Yusuf, B. Utomo
Introduction: Intestinal fatty acid binding protein (I-FABP) is expected could be used as predictor of tissue hypoperfusion. This study sought to compare the level of I-FABP between pre- and post-surgery and its associated determinants in patients with otorhinolaryngology surgeries using general anesthesia with controlled hypotension (CH) technique. Methods: We did a cross-sectional study was conducted among patients that underwent elective surgeries at Dr. Soetomo in Surabaya, Indonesia. Those who underwent surgeries using general anesthesia with CH technique were recruited in the study. I-FABP levels were measured using ELISA 1 hour before the surgery and 30 minutes after general anesthesia ended. Fisher's exact test and Mann-Whitney test were used to determine the determinants associated with changes of I-FABP level between pre- and post-surgery. Results: A total of 31 patients who underwent the surgeries with general anesthesia and CH technique were included in this study. The median of I-FABP level pre- and post-surgery was 0.639 ng/mL to 0.779 ng/mL, respectively suggesting there was a significant increase of I-FABP level after the CH technique (p<0.001). Gender and ASA score did not associate with I-FABP level changes pre- and post-surgery with p=0.333 and 0.060, respectively. Age, BMI did not associate with changes of I-FABP level between pre- and post-surgery (p=0.747 and p=0.051, respectively). Surgery duration, anesthesia duration, systolic, diastolic and MAP all also had no association with changes of the I-FABP level with p>0.05. Conclusion: The levels of I-FABP increased significantly in post-surgery in patients with otorhinolaryngology surgeries using general anesthesia with CH. Further studies are warranted to confirm this result with bigger sample size.
{"title":"Comparation of intestinal fatty acid binding protein (I-FABP) level between pre- and post-surgery and its associated determinants in patients with microscopic otorhinolaryngology surgeries","authors":"Y. Atmajaya, Mohammad Satriyo Wibowo, P. Airlangga, Maulydia, Prihatma Kriswidyatomo, Muhtarum Yusuf, B. Utomo","doi":"10.15562/bmj.v11i3.3893","DOIUrl":"https://doi.org/10.15562/bmj.v11i3.3893","url":null,"abstract":"Introduction: Intestinal fatty acid binding protein (I-FABP) is expected could be used as predictor of tissue hypoperfusion. This study sought to compare the level of I-FABP between pre- and post-surgery and its associated determinants in patients with otorhinolaryngology surgeries using general anesthesia with controlled hypotension (CH) technique.\u0000Methods: We did a cross-sectional study was conducted among patients that underwent elective surgeries at Dr. Soetomo in Surabaya, Indonesia. Those who underwent surgeries using general anesthesia with CH technique were recruited in the study. I-FABP levels were measured using ELISA 1 hour before the surgery and 30 minutes after general anesthesia ended. Fisher's exact test and Mann-Whitney test were used to determine the determinants associated with changes of I-FABP level between pre- and post-surgery.\u0000Results: A total of 31 patients who underwent the surgeries with general anesthesia and CH technique were included in this study. The median of I-FABP level pre- and post-surgery was 0.639 ng/mL to 0.779 ng/mL, respectively suggesting there was a significant increase of I-FABP level after the CH technique (p<0.001). Gender and ASA score did not associate with I-FABP level changes pre- and post-surgery with p=0.333 and 0.060, respectively. Age, BMI did not associate with changes of I-FABP level between pre- and post-surgery (p=0.747 and p=0.051, respectively). Surgery duration, anesthesia duration, systolic, diastolic and MAP all also had no association with changes of the I-FABP level with p>0.05.\u0000Conclusion: The levels of I-FABP increased significantly in post-surgery in patients with otorhinolaryngology surgeries using general anesthesia with CH. Further studies are warranted to confirm this result with bigger sample size.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43457355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andy Nauman Saputra, P. Airlangga, Boby Abdul Rahman, Edward Kusuma, Prihatma Kriswidyatomo, Christrijogo Sumartomo
Introduction: Acute kidney injury (AKI) is a sudden decrease in kidney function due to damage within seven days or less, thus inducing an early stress response that can be promptly detected by biomarkers, such as Neutrophil Gelatinase-Associated Lipocalin (NGAL). The aim of this study was to analyse the role of NGAL level as a biomarker of postoperative prerenal AKI in patients who underwent otorhinolaryngology surgery with controlled hypotension. Methods: A prospective study was conducted among patients that underwent otorhinolaryngology surgery with controlled hypotension. Patients were selected with purposive sampling. NGAL level was measured using enzyme-linked immunosorbent assay (ELISA) from venous blood collected 1-hour pre- and 2-hour post-surgery. NGAL levels were compared between preoperative and postoperative states. Wilcoxon and Spearman test were used to determine the correlation between NGAL levels and parameters of AKI. Results: A total of 30 patients underwent a varies of otorhinolaryngology surgeries were recruited in this study. Our data suggested no significant different between the level of NGAL during preoperative and postoperative (184.73±120.09 ng/mL vs 175.80±129.97 ng/mL). Pre-operative laboratory parameters of AKI such as blood urea nitrogen (BUN), serum creatine (SCr), BUN/SCr ratio, and GFR had no correlation with postoperative NGAL level. In addition, systolic blood pressure, diastolic blood pressure, MAP, heart rate, EtCO2, duration of surgery and the duration of controlled hypotension had no correlation with postoperative NGAL. Conclusion: NGAL levels have nonsignificant role as biomarker of incidence of postoperative prerenal AKI in patients who receiving otorhinolaryngology surgery with controlled hypotension. However, further study with the bigger sample size is warrant to confirm the findings of this study.
简介:急性肾损伤(AKI)是指在7天或更短时间内因损伤而导致肾功能突然下降，从而诱发早期应激反应，可通过生物标志物(如中性粒细胞明胶酶相关脂载蛋白(NGAL))及时检测到。本研究的目的是分析NGAL水平在接受耳鼻喉外科手术并控制低血压的患者中作为术后肾性AKI的生物标志物的作用。方法:对接受耳鼻喉外科手术的控制性低血压患者进行前瞻性研究。采用有目的的抽样方法选择患者。术前1小时和术后2小时采集静脉血，采用酶联免疫吸附试验(ELISA)测定NGAL水平。比较术前和术后状态下NGAL水平。采用Wilcoxon和Spearman检验确定NGAL水平与AKI参数的相关性。结果:本研究共招募了30例接受不同耳鼻喉科手术的患者。我们的数据显示术前和术后NGAL水平无显著差异(184.73±120.09 ng/mL vs 175.80±129.97 ng/mL)。AKI术前实验室指标如血尿素氮(BUN)、血清肌酸(SCr)、BUN/SCr比值、GFR与术后NGAL水平无相关性。收缩压、舒张压、MAP、心率、EtCO2、手术时间、控制性低血压持续时间与术后NGAL无相关性。结论:NGAL水平对接受耳鼻喉外科手术的控制性低血压患者术后肾前AKI发生率的生物标志物作用不显著。然而，本研究的结果还有待于进一步的大样本量的研究来证实。
{"title":"Role of neutrophil gelatinase-associated lipocalin (NGAL) as a acute prerenal kidney injury marker: Exploring factors associated with its postoperative levels in hypotension-controlled otorhinolaryngology surgery","authors":"Andy Nauman Saputra, P. Airlangga, Boby Abdul Rahman, Edward Kusuma, Prihatma Kriswidyatomo, Christrijogo Sumartomo","doi":"10.15562/bmj.v11i3.3868","DOIUrl":"https://doi.org/10.15562/bmj.v11i3.3868","url":null,"abstract":"Introduction: Acute kidney injury (AKI) is a sudden decrease in kidney function due to damage within seven days or less, thus inducing an early stress response that can be promptly detected by biomarkers, such as Neutrophil Gelatinase-Associated Lipocalin (NGAL). The aim of this study was to analyse the role of NGAL level as a biomarker of postoperative prerenal AKI in patients who underwent otorhinolaryngology surgery with controlled hypotension.\u0000Methods: A prospective study was conducted among patients that underwent otorhinolaryngology surgery with controlled hypotension. Patients were selected with purposive sampling. NGAL level was measured using enzyme-linked immunosorbent assay (ELISA) from venous blood collected 1-hour pre- and 2-hour post-surgery. NGAL levels were compared between preoperative and postoperative states. Wilcoxon and Spearman test were used to determine the correlation between NGAL levels and parameters of AKI.\u0000Results: A total of 30 patients underwent a varies of otorhinolaryngology surgeries were recruited in this study. Our data suggested no significant different between the level of NGAL during preoperative and postoperative (184.73±120.09 ng/mL vs 175.80±129.97 ng/mL). Pre-operative laboratory parameters of AKI such as blood urea nitrogen (BUN), serum creatine (SCr), BUN/SCr ratio, and GFR had no correlation with postoperative NGAL level. In addition, systolic blood pressure, diastolic blood pressure, MAP, heart rate, EtCO2, duration of surgery and the duration of controlled hypotension had no correlation with postoperative NGAL.\u0000Conclusion: NGAL levels have nonsignificant role as biomarker of incidence of postoperative prerenal AKI in patients who receiving otorhinolaryngology surgery with controlled hypotension. However, further study with the bigger sample size is warrant to confirm the findings of this study.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41964939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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