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Perinatal and infant mental health care in Austria : Mapping of existing prevention, screening, and care services. 奥地利的围产期和婴儿心理保健:现有预防、筛查和护理服务的制图。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2025-03-01 Epub Date: 2024-12-30 DOI: 10.1007/s40211-024-00516-0
I Zechmeister-Koss, C Hörtnagl, Astrid Lampe, J L Paul

Purpose: Perinatal mental illness (PMI) is one of the major health problems during pregnancy and one year after birth (the perinatal period), with robust evidence of its potentially detrimental effects on the parent's and child's health. Many countries have prioritised perinatal and infant mental health care (PIMHC). In Austria, it is currently unknown how many services are available in which region. The paper aims to map the current PIMHC landscape.

Methods: Using publicly accessible sources, such as health reports or organisation websites and supplementary information from experts, we collected data on eight characteristics of services to prevent, early identify, treat or support parents with a PMI. We extracted the information into tables, narratively summarised the results and presented a geographical visualisation of service availability.

Results: While there is currently no standardised nationwide systematic screening for PMI in place, there are a variety of services to support and treat parents with a PMI of different severity in Austria. However, there are large regional variations and gaps in care, particularly regarding specialised PIMHC and trained staff, leading to unequal access. PIMHC primarily addresses mothers and involves many, mostly public, providers and funding sources.

Conclusion: There is an urgent need to reduce the regional disparities regarding specialised PIMHC, ensuring adequate referrals and treatment and reducing inequalities in access to care. The results also call for a national strategy and defined political, administrative and service provider responsibilities based on international evidence-based recommendations. Investing in the training of staff and defined care pathways seems warranted.

目的:围产期精神疾病(PMI)是怀孕期间和出生后一年(围产期)的主要健康问题之一,有强有力的证据表明它对父母和儿童的健康有潜在的有害影响。许多国家已将围产期和婴儿精神卫生保健列为优先事项。在奥地利,目前还不知道在哪个地区有多少服务。本文旨在绘制PIMHC的现状。方法:利用可公开获取的资源,如健康报告或组织网站以及专家的补充信息,我们收集了有关预防、早期识别、治疗或支持患有PMI的父母的服务的八个特征的数据。我们将信息提取到表格中,叙述总结结果,并呈现服务可用性的地理可视化。结果:虽然目前没有针对PMI的标准化全国性系统筛查,但奥地利有多种服务来支持和治疗患有不同严重程度PMI的父母。然而,在护理方面存在很大的区域差异和差距,特别是在专门的PIMHC和训练有素的工作人员方面,导致获得不平等。PIMHC主要针对母亲,并涉及许多(主要是公共)提供者和资金来源。结论:迫切需要缩小专业化PIMHC的地区差异,确保充分的转诊和治疗,减少获得护理的不平等。研究结果还呼吁制定一项国家战略,并根据国际上以证据为基础的建议确定政治、行政和服务提供者的责任。投资于员工培训和明确的护理途径似乎是有必要的。
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引用次数: 0
"Don't talk to me like I am an illness": exploring patients' needs using the communication passport in an eating disorder service. "别把我当病来跟我说话":在饮食失调服务中使用交流护照探索患者的需求。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2025-03-01 Epub Date: 2024-07-12 DOI: 10.1007/s40211-024-00501-7
Zhuo Li, Dimitri Chubinidze, Philippa Croft, Jessica Webb, Amanda Sarpong, Elisa Zesch, Kate Tchanturia

Purpose: Social challenges are common in patients with eating disorders (ED). The presence of autistic characteristics often exacerbates social difficulties within this group, potentially affecting treatment outcomes. This study investigates the communication preferences, challenges, dislikes, and support needs of patients with ED, both with and without autistic traits, using a communication passport in a national inpatient ED service.

Methods: An explorative qualitative analysis of 38 completed communication passports was conducted to investigate patients' communication preferences, sensory needs, struggles and dislikes, and areas of support required, paying particular attention to the distinct needs of patients with high levels of autistic traits.

Results: The communication passport provided valuable insights into patients' communication preferences, sensory sensitivities, challenges, and support needed. Patients also used the passports to share information about their strengths, personal identity, and life beyond the hospital.

Conclusion: The communication passport fosters a deeper understanding of patients' needs and may support clinicians in care planning and communication strategies tailored to each patient's needs. Regular evaluation and updates are warranted to ensure its usability and accessibility by the wider care team.

目的:饮食失调症(ED)患者普遍存在社交障碍。自闭症特征的存在往往会加剧这一群体的社交困难,从而可能影响治疗效果。本研究在一项全国性的饮食失调症(ED)住院病人服务中,使用交流护照调查了饮食失调症(ED)患者的交流偏好、挑战、厌恶和支持需求,包括有自闭症特征和无自闭症特征的患者:对 38 份填写完整的交流护照进行了探索性定性分析,以调查患者的交流偏好、感官需求、挣扎和厌恶以及所需的支持领域,尤其关注具有高度自闭症特征的患者的独特需求:交流护照为了解患者的交流偏好、感官敏感性、面临的挑战和所需的支持提供了宝贵的信息。患者还利用护照分享了他们的长处、个人身份和院外生活等信息:交流护照有助于加深对患者需求的了解,并可帮助临床医生制定护理计划和交流策略,以满足每位患者的需求。有必要对其进行定期评估和更新,以确保其可用性和更广泛的护理团队的可及性。
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引用次数: 0
kultur im kontext. 文化背景。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2025-03-01 DOI: 10.1007/s40211-025-00521-x
Maria Höger-Weinmüller
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引用次数: 0
Qualitative and quantitative assessments of pain in anxious and depressed patients : Are there differences? 焦虑和抑郁患者疼痛的定性和定量评估:有区别吗?
IF 1.1 Q4 PSYCHIATRY Pub Date : 2025-03-01 Epub Date: 2025-02-20 DOI: 10.1007/s40211-025-00519-5
Michelle Dos Santos Severino Costa, Maria Júlia Logato, Caroline Carvalho Mageste, Diérisson Souza Simão, Renato Santiago Gomez

Background: Pain is a multidimensional and subjective experience, and its perception is influenced by sensory, emotional, and behavioral factors. This work aims to evaluate the influence of depression and anxiety in the quantitative and qualitative assessment of chronic pain.

Methods: This is a cross-sectional study carried out at the Multidisciplinary Pain Center of the Clinical Hospital of the Federal University of Minas Gerais. A total of 103 patients were interviewed and evaluated using the following instruments: McGill Questionnaire, visual numerical scale, Hospital Anxiety and Depression Scale and the Medical Outcomes Study SF-36.

Results: The affective, sensory and miscellaneous categories of anxious patients were higher than the nonanxious population (p < 0.05). In the depressed population, the "affective" category was higher than the nondepressed population (p < 0.05). Regarding the anxious and depressed population, the affective, sensory and miscellaneous categories were superior to the nonanxious and nondepressed population (p < 0.05).

Discussion: Depression and anxiety are the most common psychiatric disorders in the population with chronic pain, with a prevalence of 30-40%. In the presence of anxiety and depression, a worse qualitative evaluation was observed. The higher the scores obtained in the assessment of these two mental disorders, the higher the pain index found, and the higher pain index correlates with a lower quality of life.

Conclusion: The presence of anxiety and depression altered the qualitative assessment of pain, making it more unpleasant. The pain index correlated with quality of life without, however, being related to pain intensity.

背景:疼痛是一种多维度的主观体验,其感知受感觉、情绪和行为因素的影响。本研究旨在评估抑郁和焦虑对慢性疼痛定量和定性评估的影响。方法:这是在米纳斯吉拉斯州联邦大学临床医院多学科疼痛中心进行的一项横断面研究。采用McGill问卷、视觉数字量表、医院焦虑抑郁量表和SF-36对103例患者进行访谈和评估。结果:焦虑患者的情感、感觉和杂项类别高于非焦虑人群(p )讨论:抑郁和焦虑是慢性疼痛人群中最常见的精神障碍,患病率为30-40%。在存在焦虑和抑郁时,观察到较差的定性评价。在这两种精神障碍的评估中得分越高,疼痛指数越高,疼痛指数越高,生活质量越低。结论:焦虑和抑郁的存在改变了对疼痛的定性评估,使疼痛更加不愉快。疼痛指数与生活质量相关,但与疼痛强度无关。
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引用次数: 0
Gender dysphoria in adolescence: examining the rapid-onset hypothesis. 青春期性别焦虑症:研究快速发病假说。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2025-03-01 Epub Date: 2024-07-01 DOI: 10.1007/s40211-024-00500-8
André Leonhardt, Martin Fuchs, Manuela Gander, Kathrin Sevecke

The sharp rise in the number of predominantly natal female adolescents experiencing gender dysphoria and seeking treatment in specialized clinics has sparked a contentious and polarized debate among both the scientific community and the public sphere. Few explanations have been offered for these recent developments. One proposal that has generated considerable attention is the notion of "rapid-onset" gender dysphoria, which is assumed to apply to a subset of adolescents and young adults. First introduced by Lisa Littman in a 2018 study of parental reports, it describes a subset of youth, primarily natal females, with no childhood indicators of gender dysphoria but with a sudden emergence of gender dysphoria symptoms during puberty or after its completion. For them, identifying as transgender is assumed to serve as a maladaptive coping mechanism for underlying mental health issues and is linked to social influences from peer groups and through social media. The purpose of this article is to analyze this theory and its associated hypotheses against the existing evidence base and to discuss its potential implications for future research and the advancement of treatment paradigms.

以新生儿为主的女性青少年出现性别焦虑症并到专门诊所寻求治疗的人数急剧上升,这在科学界和公共领域引发了一场有争议和两极分化的辩论。对于这些最新进展,几乎没有人给出解释。其中一个引起广泛关注的建议是 "快速发作 "性别焦虑症的概念,它被认为适用于青少年和年轻成年人。该概念由丽莎-利特曼(Lisa Littman)在 2018 年的一项家长报告研究中首次提出,它描述了一部分青少年,主要是出生后的女性,在童年时期没有性别焦虑症的迹象,但在青春期或青春期结束后突然出现性别焦虑症状。对他们来说,变性被认为是对潜在心理健康问题的一种适应不良的应对机制,并与来自同龄群体和社交媒体的社会影响有关。本文旨在根据现有的证据基础分析这一理论及其相关假设,并讨论其对未来研究和治疗范式进步的潜在影响。
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引用次数: 0
bericht aus dem ögkjp-vorstand. OKP董事会报告。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2025-03-01 DOI: 10.1007/s40211-025-00520-y
A Karwautz
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引用次数: 0
bericht aus dem ögpp-vorstand. 董事会报告。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2025-03-01 DOI: 10.1007/s40211-025-00522-w
Goedl-Fleischhacker U
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引用次数: 0
Childhood maltreatment and the risk of eating disorders: a meta-analysis of observational studies. 童年虐待与饮食失调的风险:观察性研究的荟萃分析。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2025-03-01 Epub Date: 2024-08-28 DOI: 10.1007/s40211-024-00505-3
Sohrab Amiri, Mahtab Sabzehparvar

Objective: The purpose of this systematic review and meta-analysis is to examine the relationship between childhood maltreatment as a variable of exposure and eating disorders as an outcome.

Methods: PubMed, Web of Science, and Google Scholar were searched to find manuscripts related to the current research. The search was conducted up until October 2023 and limited to the English language. An odds ratio (OR) based on the random effects method was used to combine studies. One subgroup analysis was performed based on the type of eating disorder and another based on the type of childhood maltreatment.

Results: Thirty eligible studies were recognized for this research. Childhood maltreatment was associated with a rate of eating disorders of more than double: OR 2.37 with 95% confidence interval (CI) 1.84-3.06 (P < 0.001; I2 = 92.6%). Childhood maltreatment was associated with anorexia nervosa (OR 1.89, 95% CI 1.47-2.42; Z = 5.03; P < 0.001; I2 = 0%), bulimia nervosa (OR 2.64, 95% CI 1.34-5.17; Z = 2.82; P = 0.005; I2 = 93.1%), and binge eating disorder (OR 1.76, 95% CI 1.38-2.26; Z = 4.52; P < 0.001; I2 = 80.2%).

Conclusion: The findings of this research showed that childhood maltreatment significantly increases the risk of eating disorders. Therefore, in understanding the mechanisms related to eating disorders, it is necessary to pay attention to the issue of the childhood living environment and the traumatic experiences of that time.

目的本系统综述和荟萃分析旨在研究作为暴露变量的儿童虐待与作为结果的饮食失调之间的关系:搜索了 PubMed、Web of Science 和 Google Scholar,以找到与当前研究相关的手稿。搜索时间截至 2023 年 10 月,仅限于英语。采用基于随机效应法的几率比(OR)来合并研究。根据饮食失调的类型和儿童虐待的类型分别进行了分组分析:本研究共收到 30 项符合条件的研究。童年虐待与饮食失调的相关性超过一倍:OR值为2.37,95%置信区间(CI)为1.84-3.06(P 2 = 92.6%)。童年虐待与神经性厌食症(OR 1.89,95% CI 1.47-2.42;Z = 5.03;P 2 = 0%)、神经性贪食症(OR 2.64,95% CI 1.34-5.17;Z = 2.82;P = 0.005;I2 = 93.1%)和暴饮暴食症(OR 1.76,95% CI 1.38-2.26;Z = 4.52;P 2 = 80.2%)有关:本研究结果表明,童年虐待会显著增加罹患饮食失调症的风险。因此,在了解进食障碍的相关机制时,有必要关注儿童时期的生活环境和创伤经历问题。
{"title":"Childhood maltreatment and the risk of eating disorders: a meta-analysis of observational studies.","authors":"Sohrab Amiri, Mahtab Sabzehparvar","doi":"10.1007/s40211-024-00505-3","DOIUrl":"10.1007/s40211-024-00505-3","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this systematic review and meta-analysis is to examine the relationship between childhood maltreatment as a variable of exposure and eating disorders as an outcome.</p><p><strong>Methods: </strong>PubMed, Web of Science, and Google Scholar were searched to find manuscripts related to the current research. The search was conducted up until October 2023 and limited to the English language. An odds ratio (OR) based on the random effects method was used to combine studies. One subgroup analysis was performed based on the type of eating disorder and another based on the type of childhood maltreatment.</p><p><strong>Results: </strong>Thirty eligible studies were recognized for this research. Childhood maltreatment was associated with a rate of eating disorders of more than double: OR 2.37 with 95% confidence interval (CI) 1.84-3.06 (P < 0.001; I<sup>2</sup> = 92.6%). Childhood maltreatment was associated with anorexia nervosa (OR 1.89, 95% CI 1.47-2.42; Z = 5.03; P < 0.001; I<sup>2</sup> = 0%), bulimia nervosa (OR 2.64, 95% CI 1.34-5.17; Z = 2.82; P = 0.005; I<sup>2</sup> = 93.1%), and binge eating disorder (OR 1.76, 95% CI 1.38-2.26; Z = 4.52; P < 0.001; I<sup>2</sup> = 80.2%).</p><p><strong>Conclusion: </strong>The findings of this research showed that childhood maltreatment significantly increases the risk of eating disorders. Therefore, in understanding the mechanisms related to eating disorders, it is necessary to pay attention to the issue of the childhood living environment and the traumatic experiences of that time.</p>","PeriodicalId":44560,"journal":{"name":"NEUROPSYCHIATRIE","volume":" ","pages":"36-46"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between schizophrenia or schizoaffective disorder and type 1 diabetes mellitus: a scoping review of observational studies. 精神分裂症或分裂情感障碍与 1 型糖尿病之间的关系:观察性研究的范围界定综述。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2024-12-01 Epub Date: 2024-06-04 DOI: 10.1007/s40211-024-00499-y
Yi-Chun Liu, Yin-To Liao, Kuan-Han Lin

Objective: Both schizophrenia and type 1 diabetes mellitus (T1D) are known as immune-related disorders. We systematically reviewed observational studies to explore the relationship between schizophrenia or schizoaffective disorder and T1D.

Methods: A preliminary search of articles was completed using the following databases: Airiti Library, CINAHL Complete (via EBSCOhost), OVID MEDLINE, Embase, and PubMed. Two researchers independently assessed each study's quality based on Joanna Briggs Institute (JBI). A narrative review summarized the potential relationship between the two diseases.

Results: Eleven studies were included in the final analysis. Six observational studies investigated the risk of schizophrenia and schizoaffective disorder in patients with T1D. Two studies showed negative correlations, one showed no correlation, and three showed positive correlations. On the other hand, five studies reported the prevalence of T1D in patients with schizophrenia. Two of them showed positive associations, and three others showed no association. Although the majority of the included studies suggested a positive association between the two medical conditions, these studies were still too heterogeneous to draw consistent results.

Conclusion: We found conflicting results regarding the bidirectional relationship between schizophrenia or schizoaffective disorder and T1D. These may stem from differences in study design, sampling methods, or definition of diagnoses, which are essential aspects to consider in future research.

目的:精神分裂症和1型糖尿病(T1D)都是众所周知的免疫相关疾病。我们对观察性研究进行了系统回顾,以探讨精神分裂症或精神分裂情感障碍与 T1D 之间的关系:我们使用以下数据库对文章进行了初步检索:Airiti图书馆、CINAHL Complete(通过EBSCOhost)、OVID MEDLINE、Embase和PubMed。两名研究人员根据乔安娜-布里格斯研究所(JBI)对每项研究的质量进行了独立评估。一篇叙述性综述总结了两种疾病之间的潜在关系:最终分析纳入了 11 项研究。六项观察性研究调查了T1D患者罹患精神分裂症和精神分裂情感障碍的风险。其中两项研究结果呈负相关,一项研究结果无相关性,三项研究结果呈正相关。另一方面,有五项研究报告了 T1D 在精神分裂症患者中的患病率。其中两项研究表明两者呈正相关,另外三项研究表明两者之间没有关联。尽管纳入的大多数研究表明这两种病症之间存在正相关,但这些研究仍然过于分散,无法得出一致的结果:我们发现,精神分裂症或精神分裂情感障碍与 T1D 之间的双向关系存在相互矛盾的结果。结论:我们发现精神分裂症或精神分裂情感障碍与 T1D 的双向关系存在相互矛盾的结果,这可能源于研究设计、抽样方法或诊断定义的差异,这些都是未来研究中需要考虑的重要方面。
{"title":"The relationship between schizophrenia or schizoaffective disorder and type 1 diabetes mellitus: a scoping review of observational studies.","authors":"Yi-Chun Liu, Yin-To Liao, Kuan-Han Lin","doi":"10.1007/s40211-024-00499-y","DOIUrl":"10.1007/s40211-024-00499-y","url":null,"abstract":"<p><strong>Objective: </strong>Both schizophrenia and type 1 diabetes mellitus (T1D) are known as immune-related disorders. We systematically reviewed observational studies to explore the relationship between schizophrenia or schizoaffective disorder and T1D.</p><p><strong>Methods: </strong>A preliminary search of articles was completed using the following databases: Airiti Library, CINAHL Complete (via EBSCOhost), OVID MEDLINE, Embase, and PubMed. Two researchers independently assessed each study's quality based on Joanna Briggs Institute (JBI). A narrative review summarized the potential relationship between the two diseases.</p><p><strong>Results: </strong>Eleven studies were included in the final analysis. Six observational studies investigated the risk of schizophrenia and schizoaffective disorder in patients with T1D. Two studies showed negative correlations, one showed no correlation, and three showed positive correlations. On the other hand, five studies reported the prevalence of T1D in patients with schizophrenia. Two of them showed positive associations, and three others showed no association. Although the majority of the included studies suggested a positive association between the two medical conditions, these studies were still too heterogeneous to draw consistent results.</p><p><strong>Conclusion: </strong>We found conflicting results regarding the bidirectional relationship between schizophrenia or schizoaffective disorder and T1D. These may stem from differences in study design, sampling methods, or definition of diagnoses, which are essential aspects to consider in future research.</p>","PeriodicalId":44560,"journal":{"name":"NEUROPSYCHIATRIE","volume":" ","pages":"163-173"},"PeriodicalIF":1.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of attention-deficit/hyperactivity disorder with inflammatory diseases. Results from the nationwide German Health Interview and Examination Survey for Children and Adolescents (KiGGS). 注意缺陷/多动症与炎症性疾病的关系。德国全国儿童和青少年健康访谈和检查调查(KiGGS)的结果。
IF 1.1 Q4 PSYCHIATRY Pub Date : 2024-12-01 Epub Date: 2023-08-17 DOI: 10.1007/s40211-023-00479-8
Lena Boemanns, Julia Staab, Thomas Meyer

Background: Despite conflicting data, some studies have suggested a pathophysiological relationship between inflammation and attention-deficit/hyperactivity disorder (ADHD).

Methods: Using data from the nationwide and representative German Health Interview and Examination Survey for Children and Adolescents (KiGGS; n = 6922 study participants aged 11-17 years), this post hoc analysis assessed the associations between ADHD and three common inflammatory diseases.

Results: Results showed univariate associations between ADHD and lifetime inflammatory diseases including atopic dermatitis (p = 0.002), otitis media (p = 0.001), and herpes simplex infection (p = 0.032). In logistic regression models adjusted for clinically relevant confounders, we found that ADHD remained a significant predictor of all three inflammatory diseases (atopic dermatitis, Exp(β) = 1.672, 95% confidence interval [CI] 1.239-2.257, p = 0.001; otitis media, Exp(β) = 1.571, 95% CI 1.209-2.040, p = 0.001; herpes simplex, Exp(β) = 1.483, 95% CI 1.137-1.933, p = 0.004).

Conclusion: Our findings demonstrate a positive link between ADHD and peripheral inflammatory diseases, including atopic dermatitis, otitis media, and herpes simplex infection. Further studies are needed to understand the exact pathophysiological mechanisms underlying these associations.

背景:尽管数据相互矛盾,但一些研究表明炎症与注意力缺陷/多动症(ADHD)之间存在病理生理关系:尽管数据相互矛盾,但一些研究表明炎症与注意力缺陷/多动症(ADHD)之间存在病理生理关系:方法:利用具有全国代表性的德国儿童和青少年健康访谈和检查调查(KiGGS;n = 6922 名 11-17 岁的研究参与者)的数据,进行事后分析,评估多动症与三种常见炎症之间的关系:结果显示,多动症与终生炎症性疾病(包括特应性皮炎(p = 0.002)、中耳炎(p = 0.001)和单纯疱疹病毒感染(p = 0.032))之间存在单变量关联。在调整了临床相关混杂因素的逻辑回归模型中,我们发现多动症仍然是所有三种炎症性疾病的重要预测因素(异位性皮炎,Exp(β) = 1.672,95% 置信区间 [CI] 1.239-2.257,p = 0.001;中耳炎,Exp(β) = 1.571,95% CI 1.209-2.040,p = 0.001;单纯疱疹,Exp(β) = 1.483,95% CI 1.137-1.933,p = 0.004):我们的研究结果表明,多动症与特应性皮炎、中耳炎和单纯疱疹感染等外周炎症性疾病之间存在正相关。要了解这些关联的确切病理生理机制,还需要进一步的研究。
{"title":"Associations of attention-deficit/hyperactivity disorder with inflammatory diseases. Results from the nationwide German Health Interview and Examination Survey for Children and Adolescents (KiGGS).","authors":"Lena Boemanns, Julia Staab, Thomas Meyer","doi":"10.1007/s40211-023-00479-8","DOIUrl":"10.1007/s40211-023-00479-8","url":null,"abstract":"<p><strong>Background: </strong>Despite conflicting data, some studies have suggested a pathophysiological relationship between inflammation and attention-deficit/hyperactivity disorder (ADHD).</p><p><strong>Methods: </strong>Using data from the nationwide and representative German Health Interview and Examination Survey for Children and Adolescents (KiGGS; n = 6922 study participants aged 11-17 years), this post hoc analysis assessed the associations between ADHD and three common inflammatory diseases.</p><p><strong>Results: </strong>Results showed univariate associations between ADHD and lifetime inflammatory diseases including atopic dermatitis (p = 0.002), otitis media (p = 0.001), and herpes simplex infection (p = 0.032). In logistic regression models adjusted for clinically relevant confounders, we found that ADHD remained a significant predictor of all three inflammatory diseases (atopic dermatitis, Exp(β) = 1.672, 95% confidence interval [CI] 1.239-2.257, p = 0.001; otitis media, Exp(β) = 1.571, 95% CI 1.209-2.040, p = 0.001; herpes simplex, Exp(β) = 1.483, 95% CI 1.137-1.933, p = 0.004).</p><p><strong>Conclusion: </strong>Our findings demonstrate a positive link between ADHD and peripheral inflammatory diseases, including atopic dermatitis, otitis media, and herpes simplex infection. Further studies are needed to understand the exact pathophysiological mechanisms underlying these associations.</p>","PeriodicalId":44560,"journal":{"name":"NEUROPSYCHIATRIE","volume":" ","pages":"182-188"},"PeriodicalIF":1.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10070888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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