Pub Date : 2016-01-01DOI: 10.22452/MJLIS.VOL21NO3.1
C. Yu, J. Shieh
Subject analysis is an approach for analyzing the development of academic research and paradigm shifts in Library and Information Science. Through content analysis and categorization of academic literatures, the focus in different development stages of research fields, such as research areas, issues of concern, and temporal and spatial shifts, is summarized and analyzed. This study proposes an analytical framework for the topics of electronic resources by adopting the Medical Subject Headings (MeSH) posted by the U.S. National Library of Medicine (NLM) as the basis for subject classification. The study covers cancer research as a subject case to verify and compare the databases of SCImago Journal and Country Rank and the bibliographies of PubMed biomedical literatures. Through systematic collection, collation, and analysis of raw data, variables such as specific key topics, number of publications, and year of publications are segmented for statistical analysis. The findings show that cancer research is a developing trend, and the compiled information provides a diversity of study topics for informatics and information behavior research.
主题分析是分析图书馆情报学学术研究发展和范式转变的一种方法。通过对学术文献的内容分析和分类，总结分析研究领域在不同发展阶段的重点，如研究领域、关注问题、时空变迁等。本研究以美国国家医学图书馆(National Library of Medicine, NLM)公布的医学主题词(Medical Subject heading, MeSH)为主题分类基础，提出电子资源主题的分析架构。本研究以癌症研究为主体案例，对SCImago Journal和Country Rank数据库以及PubMed生物医学文献书目进行验证和比较。通过对原始数据的系统收集、整理和分析，将特定的关键主题、出版物数量、出版物年份等变量分段进行统计分析。研究结果表明，癌症研究是一种发展趋势，所汇编的信息为信息学和信息行为研究提供了多样化的研究主题。
{"title":"Subject analysis of cancer research: Procedure and identification of core literature","authors":"C. Yu, J. Shieh","doi":"10.22452/MJLIS.VOL21NO3.1","DOIUrl":"https://doi.org/10.22452/MJLIS.VOL21NO3.1","url":null,"abstract":"Subject analysis is an approach for analyzing the development of academic research and paradigm shifts in Library and Information Science. Through content analysis and categorization of academic literatures, the focus in different development stages of research fields, such as research areas, issues of concern, and temporal and spatial shifts, is summarized and analyzed. This study proposes an analytical framework for the topics of electronic resources by adopting the Medical Subject Headings (MeSH) posted by the U.S. National Library of Medicine (NLM) as the basis for subject classification. The study covers cancer research as a subject case to verify and compare the databases of SCImago Journal and Country Rank and the bibliographies of PubMed biomedical literatures. Through systematic collection, collation, and analysis of raw data, variables such as specific key topics, number of publications, and year of publications are segmented for statistical analysis. The findings show that cancer research is a developing trend, and the compiled information provides a diversity of study topics for informatics and information behavior research.","PeriodicalId":45072,"journal":{"name":"Malaysian Journal of Library & Information Science","volume":"21 1","pages":"1-20"},"PeriodicalIF":1.3,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68663453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-10-27DOI: 10.1111/j.1432-2277.2008.00782.x
Jun Li, Kailun Zhang, Jiahong Xia
The chemokine receptor CCR5 plays important roles in acute allograft rejection. In this study, we examined the inhibition of CCR5 in combination with the treatment with cyclosporine A (CsA) in chronic rejection in cardiac transplantation. Forty-five transplant recipients were randomized to three groups. Recipients in group A were treated with anti-CCR5 mAb and CsA, mice in group B were given anti-CCR5 mAb alone, and animals in group C were administered with only CsA. On day 45 after transplantation, the allografts were harvested and examined by immunohistologic technique and PT-PCR methods. Allografts treated with anti-CCR5 mAb and CsA showed significantly prolonged survival (44.73 ± 0.258 days, P < 0.01) as compared with CsA-treated group (37.00 ± 2.04 days). Treatment with anti-CCR5 mAb plus CsA significantly inhibited the progression of cardiac allograft vasculopathy. Our findings demonstrated that anti-CCR5 mAb in combination with CsA can prolong the survival of allograft through their cardio-protective and immunomodulative properties. Thus, combined administration of anti-CCR5 mAb and CsA may become a new therapeutic approach for the prevention of cardiac graft failure that has not been obviated by conventional immunosuppressive agents.
{"title":"RETRACTED: Chronic cardiac allograft rejection in mice is alleviated by inhibition of CCR5 in combination with cyclosporine A.","authors":"Jun Li, Kailun Zhang, Jiahong Xia","doi":"10.1111/j.1432-2277.2008.00782.x","DOIUrl":"10.1111/j.1432-2277.2008.00782.x","url":null,"abstract":"<p><p>The chemokine receptor CCR5 plays important roles in acute allograft rejection. In this study, we examined the inhibition of CCR5 in combination with the treatment with cyclosporine A (CsA) in chronic rejection in cardiac transplantation. Forty-five transplant recipients were randomized to three groups. Recipients in group A were treated with anti-CCR5 mAb and CsA, mice in group B were given anti-CCR5 mAb alone, and animals in group C were administered with only CsA. On day 45 after transplantation, the allografts were harvested and examined by immunohistologic technique and PT-PCR methods. Allografts treated with anti-CCR5 mAb and CsA showed significantly prolonged survival (44.73 ± 0.258 days, P < 0.01) as compared with CsA-treated group (37.00 ± 2.04 days). Treatment with anti-CCR5 mAb plus CsA significantly inhibited the progression of cardiac allograft vasculopathy. Our findings demonstrated that anti-CCR5 mAb in combination with CsA can prolong the survival of allograft through their cardio-protective and immunomodulative properties. Thus, combined administration of anti-CCR5 mAb and CsA may become a new therapeutic approach for the prevention of cardiac graft failure that has not been obviated by conventional immunosuppressive agents.</p>","PeriodicalId":45072,"journal":{"name":"Malaysian Journal of Library & Information Science","volume":"22 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2008-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85430470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-01-01DOI: 10.1163/9789004337862_lgbo_com_210162
A. Rahman
{"title":"Unesco Public Library Manifesto, 1994","authors":"A. Rahman","doi":"10.1163/9789004337862_lgbo_com_210162","DOIUrl":"https://doi.org/10.1163/9789004337862_lgbo_com_210162","url":null,"abstract":"","PeriodicalId":45072,"journal":{"name":"Malaysian Journal of Library & Information Science","volume":"1 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"1970-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64537177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：