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A Principled Account of AMR Global Governance Solidarity, Subsidiarity, and Stewardship. 抗微生物药物耐药性全球治理的原则解释团结、辅助和管理。
IF 1.9 3区 哲学 Q2 ETHICS Pub Date : 2023-03-01 DOI: 10.1007/s10728-023-00456-w
Thana C de Campos-Rudinsky

This commentary defines what shared yet differentiated ethical responsibilities to tackle antimicrobial resistance (AMR) mean, by introducing a threefold principled account of AMR global governance. It argues that the principles of solidarity, subsidiarity, and stewardship can be especially helpful for further justifying some of the universal, differentiated, and individual responsibilities that Van Katwyk et al propose. The upshot of my threefold principled account of AMR global governance is a less ambitious AMR treaty, one that can only justify (i) universal duties of global coordination (as per the principle of solidarity); (ii) differentiated duties to local communities, which bear the primary AMR responsibilities (as per the principle of subsidiarity); and (iii) individualized duties for ensuring truthful, evidence-based, consistent, and timely shared accountable communication (as per the principle of stewardship).

本评论通过介绍抗微生物药物耐药性全球治理的三重原则,定义了应对抗微生物药物耐药性(AMR)的共同但有区别的伦理责任的含义。它认为,团结、辅助和管理原则可以特别有助于进一步证明Van Katwyk等人提出的一些普遍的、有区别的和个人的责任。我对抗微生物药物耐药性全球治理的三方面原则解释的结果是一个不那么雄心勃勃的抗微生物药物耐药性条约,它只能证明:(1)全球协调的普遍责任(根据团结原则);对地方社区有区别的责任,地方社区承担抗菌素耐药性的主要责任(按照辅助原则);(iii)确保真实、循证、一致和及时分享负责任的沟通的个性化职责(根据管理原则)。
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引用次数: 0
More Carrots, Less Sticks: Encouraging Good Stewardship in the Global Antimicrobial Commons. 更多胡萝卜,更少大棒:鼓励全球抗微生物公域的良好管理。
IF 1.9 3区 哲学 Q2 ETHICS Pub Date : 2023-03-01 DOI: 10.1007/s10728-023-00455-x
Cristian Timmermann

Time-tested commons characterize by having instituted sanctioning mechanisms that are sensitive to the circumstances and motivations of non-compliers. As a proposed Global Antimicrobial Commons cannot cost-effectively develop sanctioning mechanisms that are consistently sensitive to the circumstances of the global poor, I suggest concentrating on establishing a wider set of incentives that encourages both compliance and participation.

经过时间考验的公地的特点是建立了对不遵守规定者的情况和动机敏感的制裁机制。由于拟议的全球抗微生物药物公域无法经济有效地制定对全球穷人情况始终敏感的制裁机制,我建议集中精力建立一套更广泛的激励措施,鼓励遵守和参与。
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引用次数: 0
Regulating the Global Antimicrobial Commons: Climate Agreements and Beyond. 调节全球抗微生物公域:气候协议及其他。
IF 1.9 3区 哲学 Q2 ETHICS Pub Date : 2023-03-01 DOI: 10.1007/s10728-023-00454-y
Philippe Cullet

A treaty to regulate the global antimicrobial commons can be appropriately framed around the model provided by multilateral environmental agreements. At the same time, it is not clear that a comprehensive treaty is the only possible entry point and other options, such as an agreement on technology transfer or funding may be apt starting points. Any legal instrument adopted to regulate the global antimicrobial commons needs to reflect the global South-North dichotomy and integrate the principle of common but differentiated responsibilities and respective capabilities. Further, it would need to go beyond environmental instruments that have been structured around the sovereign interests of negotiating states even when dealing with issues of global concern, such as climate change. The proposed legal instrument would also need to be based not just on the precautionary principle as a marker of the necessity to address the negative environmental and health impacts, but also be based on the interests of patients and integrate concerns raised in terms of the human right to health.

可以围绕多边环境协定提供的模式,适当地制定一项规范全球抗微生物公域的条约。与此同时,目前尚不清楚一项全面条约是否是唯一可能的切入点,而诸如关于技术转让或供资的协议等其他选择可能是合适的起点。为规范全球抗微生物公域而通过的任何法律文书都需要反映全球南北二分法,并将共同但有区别的责任原则和各自能力相结合。此外,它还需要超越围绕谈判国主权利益构建的环境工具,即使在处理气候变化等全球关注的问题时也是如此。拟议的法律文书还需要不仅以预防原则为基础,作为必须解决不利的环境和健康影响的标志,而且还需要以患者的利益为基础,并综合在健康权方面提出的关切。
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引用次数: 0
Making Use of Existing International Legal Mechanisms to Manage the Global Antimicrobial Commons: Identifying Legal Hooks and Institutional Mandates. 利用现有国际法律机制管理全球抗微生物药物公域:确定法律挂钩和机构任务。
IF 1.9 3区 哲学 Q2 ETHICS Pub Date : 2023-03-01 DOI: 10.1007/s10728-020-00393-y
Susan Rogers Van Katwyk, Isaac Weldon, Alberto Giubilini, Claas Kirchhelle, Mark Harrison, Angela McLean, Julian Savulescu, Steven J Hoffman

Antimicrobial resistance (AMR) is an urgent threat to global public health and development. Mitigating this threat requires substantial short-term action on key AMR priorities. While international legal agreements are the strongest mechanism for ensuring collaboration among countries, negotiating new international agreements can be a slow process. In the second article in this special issue, we consider whether harnessing existing international legal agreements offers an opportunity to increase collective action on AMR goals in the short-term. We highlight ten AMR priorities and several strategies for achieving these goals using existing "legal hooks" that draw on elements of international environmental, trade and health laws governing related matters that could be used as they exist or revised to include AMR. We also consider the institutional mandates of international authorities to highlight areas where additional steps could be taken on AMR without constitutional changes. Overall, we identify 37 possible mechanisms to strengthen AMR governance using the International Health Regulations, the Agreement on the Application of Sanitary and Phytosanitary Measures, the Agreement on Trade-Related Aspects of Intellectual Property Rights, the Agreement on Technical Barriers to Trade, the International Convention on the Harmonized Commodity Description and Coding System, and the Basel, Rotterdam, and Stockholm conventions. Although we identify many shorter-term opportunities for addressing AMR using existing legal hooks, none of these options are capable of comprehensively addressing all global governance challenges related to AMR, such that they should be pursued simultaneously with longer-term approaches including a dedicated international legal agreement on AMR.

抗微生物药物耐药性(AMR)是对全球公共卫生和发展的紧迫威胁。减轻这一威胁需要在关键的抗菌素耐药性优先事项上采取实质性的短期行动。虽然国际法律协定是确保国家间合作的最强有力的机制,但谈判新的国际协定可能是一个缓慢的过程。在本期特刊的第二篇文章中,我们考虑利用现有的国际法律协议是否提供了在短期内增加抗微生物药物耐药性目标的集体行动的机会。我们强调了抗菌素耐药性的十个优先事项以及利用现有的“法律挂钩”实现这些目标的若干战略,这些“法律挂钩”借鉴了管理相关事项的国际环境、贸易和卫生法的要素,这些要素可以在现有的情况下使用,或经修订后纳入抗菌素耐药性。我们还考虑国际当局的机构授权,以突出在不修改宪法的情况下可以对抗菌素耐药性采取进一步步骤的领域。总体而言,我们通过《国际卫生条例》、《实施卫生与植物检疫措施协定》、《与贸易有关的知识产权协定》、《技术性贸易壁垒协定》、《商品名称和编码统一制度国际公约》以及《巴塞尔公约》、《鹿特丹公约》和《斯德哥尔摩公约》,确定了37种加强抗生素耐药性治理的可能机制。尽管我们确定了利用现有法律手段解决抗菌素耐药性问题的许多短期机会,但这些选择都无法全面解决与抗菌素耐药性有关的所有全球治理挑战,因此,它们应该与包括专门的抗菌素耐药性国际法律协议在内的长期方法同时进行。
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引用次数: 14
Altruistic Vaccination: Insights from Two Focus Group Studies. 利他主义疫苗接种:两项焦点小组研究的启示。
IF 1.8 3区 哲学 Q2 ETHICS Pub Date : 2022-12-01 DOI: 10.1007/s10728-022-00453-5
Steven R Kraaijeveld, Bob C Mulder

Vaccination can protect vaccinated individuals and often also prevent them from spreading disease to other people. This opens up the possibility of getting vaccinated for the sake of others. In fact, altruistic vaccination has recently been conceptualized as a kind of vaccination that is undertaken primary for the benefit of others. In order to better understand the potential role of altruistic motives in people's vaccination decisions, we conducted two focus group studies with a total of 37 participants. Study 1 included three focus groups on the subject of HPV vaccination for boys. Study 2 included three focus groups on the subject of pertussis and measles vaccination for childcare workers. We found substantial evidence of other-regarding motives across all focus groups, which suggests that altruistic motives could be an important factor when it comes to people's vaccination decisions. We address the significance of these findings for vaccination policy surrounding HPV vaccination for boys and vaccination for childcare workers. We also extend the findings to normative work on vaccination for the sake of others more generally.

接种疫苗可以保护接种者,往往还能防止他们将疾病传播给其他人。这就提供了为他人接种疫苗的可能性。事实上,利他主义疫苗接种最近被概念化为一种主要为了他人利益而进行的疫苗接种。为了更好地了解利他动机在人们接种决定中的潜在作用,我们进行了两项焦点小组研究,共有 37 人参加。研究 1 包括三个焦点小组,主题是男孩接种 HPV 疫苗。研究 2 包括三个焦点小组,主题是为儿童保育员接种百日咳和麻疹疫苗。我们在所有焦点小组中都发现了大量他顾动机的证据,这表明利他动机可能是人们做出疫苗接种决定的一个重要因素。我们探讨了这些发现对围绕男孩接种 HPV 疫苗和儿童保育员接种疫苗的疫苗接种政策的意义。我们还将这些发现延伸到了更广泛的为他人接种疫苗的规范性工作中。
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引用次数: 0
The Invisible Patient: Concerns about Donor Exploitation in Stem Cell Research. 看不见的病人:对干细胞研究中供体开发的关注。
IF 1.9 3区 哲学 Q2 ETHICS Pub Date : 2022-12-01 DOI: 10.1007/s10728-022-00448-2
Pär Segerdahl

As embryonic stem cell research is commercialized, the stem cell debate may shift focus from concerns about embryo destruction to concerns about exploitation of the women who donate eggs and embryos for research. Uncomfortable with the polarization of the embryo debate, this paper proposes a more "contemplative" approach than intellectual debate to concerns about exploitation. After examining pitfalls of rigid intellectual positions on exploitation, the paper investigates the possibility of a broader understanding of donation for research where patients are seen as the intended beneficiaries of the donation. Together with other actors, research is perceived as mediating altruistic gift relationships that extend from donors to patients. The paper explores how this broader perspective on "donation for research" can open up new possibilities of understanding donation and addressing risks of exploitation.

随着胚胎干细胞研究的商业化,关于干细胞的争论可能会从对胚胎破坏的担忧转向对为研究捐献卵子和胚胎的妇女的剥削的担忧。对胚胎辩论的两极分化感到不安,本文提出了一种比智力辩论更“沉思”的方法来关注剥削。在检查了僵化的知识分子立场对剥削的陷阱之后,本文调查了更广泛地理解患者被视为捐赠的预期受益者的研究捐赠的可能性。与其他参与者一起,研究被认为是中介利他的礼物关系,从捐赠者延伸到患者。本文探讨了“为研究而捐赠”这一更广阔的视角如何为理解捐赠和应对剥削风险开辟新的可能性。
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引用次数: 0
Doctors as Resource Stewards? Translating High-Value, Cost-Conscious Care to the Consulting Room. 医生是资源管理者?将高价值、有成本意识的护理转化为咨询室。
IF 1.9 3区 哲学 Q2 ETHICS Pub Date : 2022-12-01 DOI: 10.1007/s10728-022-00446-4
Marjolein Moleman, Teun Zuiderent-Jerak, Marianne Lageweg, Gianni L van den Braak, Tjerk Jan Schuitmaker-Warnaar

After many policy attempts to tackle the persistent rise in the costs of health care, physicians are increasingly seen as potentially effective resource stewards. Frameworks including the quadruple aim, value-based health care and choosing wisely underline the importance of positive engagement of the health care workforce in reinventing the system-paving the way to real affordability by defining the right care. Current programmes focus on educating future doctors to provide 'high-value, cost-conscious care' (HVCCC), which proponents believe is the future of sustainable medical practice. Such programmes, which aim to extend population-level allocation concerns to interactions between an individual doctor and patient, have generated lively debates about the ethics of expanding doctors' professional accountability. To empirically ground this discussion, we conducted a qualitative interview study to examine what happens when resource stewardship responsibilities are extended to the consulting room. Attempts to deliver HVCCC were found to involve inevitable trade-offs between benefits to the individual patient and (social) costs, medical uncertainty and efficiency, and between resource stewardship and trust. Physicians reconcile this by justifying good-value care in terms of what is in the best interest of individual patients-redefining the currency of value from monetary costs to a patient's quality of life, and cost-conscious care as reflective medical practice. Micro-level resource stewardship thus becomes a matter of working reflexively and reducing wasteful forms of care, rather than of making difficult choices about resource allocation.

在多次尝试解决医疗费用持续上涨的政策之后,医生越来越被视为潜在有效的资源管理者。包括“四重目标”、“以价值为基础的卫生保健”和“明智选择”在内的框架强调了卫生保健工作人员积极参与重塑这一系统的重要性——通过定义正确的卫生保健为实现真正的可负担性铺平了道路。目前的项目侧重于教育未来的医生提供“高价值、有成本意识的护理”(HVCCC),支持者认为这是可持续医疗实践的未来。这些旨在将人口层面的分配问题扩展到医生和病人个体之间的互动的项目,已经引发了关于扩大医生职业责任的道德问题的激烈辩论。为了根据经验进行讨论,我们进行了定性访谈研究,以检查当资源管理责任扩展到咨询室时会发生什么。研究发现,实施HVCCC的尝试不可避免地涉及患者个人利益与(社会)成本、医疗不确定性与效率、资源管理与信任之间的权衡。为了调和这一点,医生们从病人个人的最大利益出发,为高价值的医疗服务辩护——重新定义价值的货币,从金钱成本到病人的生活质量,以及作为反思医疗实践的成本意识的医疗服务。因此,微观层面的资源管理变成了一种反射性的工作和减少浪费的护理形式,而不是对资源分配做出艰难的选择。
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引用次数: 5
Epistemic Injustice in Incident Investigations: A Qualitative Study. 事件调查中的认知不公:一项质的研究。
IF 1.9 3区 哲学 Q2 ETHICS Pub Date : 2022-12-01 DOI: 10.1007/s10728-022-00447-3
Josje Kok, David de Kam, Ian Leistikow, Kor Grit, Roland Bal

Serious incident investigations-often conducted by means of Root Cause Analysis methodologies-are increasingly seen as platforms to learn from multiple perspectives and experiences: professionals, patients and their families alike. Underlying this principle of inclusiveness is the idea that healthcare staff and service users hold unique and valuable knowledge that can inform learning, as well as the notion that learning is a social process that involves people actively reflecting on shared knowledge. Despite initiatives to facilitate inclusiveness, research shows that embracing and learning from diverse perspectives is difficult. Using the concept of 'epistemic injustice', pointing at practices of someone's knowledge being unjustly disqualified or devalued, we analyze the way incident investigations are organized and executed with the aim to understand why it is difficult to embrace and learn from the multiple perspectives voiced in incident investigations. We draw from 73 semi-structured interviews with healthcare leaders, managers, healthcare professionals, incident investigators and inspectors, document analyses and ethnographic observations. Our analysis identified several structures in the incident investigation process, that can promote or hinder an actor's epistemic contribution in the process of incident investigations. Rather than repeat calls to 'involve more' and 'listen better', we encourage policy makers to be mindful of and address the structures that can cause epistemic injustice. This can improve the outcome of incident investigations and can help to do justice to the lived experiences of the involved actors in the aftermath of a serious incident.

严重事件调查——通常通过根本原因分析方法进行——越来越被视为从多个角度和经验中学习的平台:专业人员、患者和他们的家人都一样。这一包容性原则的基础是这样一种观念,即卫生保健工作人员和服务使用者拥有独特和有价值的知识,可以为学习提供信息,以及学习是一个社会过程,涉及人们对共享知识的积极反思。尽管有促进包容性的举措,但研究表明,从不同的角度接受和学习是困难的。使用“认知不公正”的概念,指出某人的知识被不公正地取消资格或贬值的做法,我们分析了事件调查的组织和执行方式,目的是理解为什么难以接受并从事件调查中表达的多种观点中学习。我们从73个半结构化访谈中得出,访谈对象包括医疗保健领导者、管理人员、医疗保健专业人员、事件调查员和检查员、文件分析和人种学观察。我们的分析确定了事件调查过程中的几个结构,它们可以促进或阻碍行为者在事件调查过程中的认知贡献。与其重复呼吁“更多参与”和“更好地倾听”,我们鼓励政策制定者注意并解决可能导致认知不公正的结构。这可以改善事件调查的结果,并有助于在严重事件发生后公正地对待有关行为者的生活经历。
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引用次数: 3
Taming Wickedness: Towards an Implementation Framework for Medical Ethics. 驯服邪恶:医学伦理学的实施框架。
IF 1.9 3区 哲学 Q2 ETHICS Pub Date : 2022-12-01 DOI: 10.1007/s10728-022-00445-5
Erin Taylor

"Wicked" problems are characterized by intractable complexity, uncertainty, and conflict between individuals or institutions, and they inhabit almost every corner of medical ethics. Despite wide acceptance of the same ethical principles, we nevertheless disagree about how to formulate such problems, how to solve them, what would count as solving them, or even what the possible solutions are. That is, we don't always know how best to implement ethical ideals in messy real-world contexts. I sketch an implementation framework for medical ethics that can help clarify wicked problems and organize further ethics research toward their resolutions. This framework describes the procedural variables that work alongside substantive ethical ideals to deliver ethical decisions in complex real-world situations. Using controversial GM mosquito research as an example, I illustrate how the generalizable relationships between the variables clarify emerging ethical guidelines of research governance and provide a pathway to extend these guidelines in a way consistent with our ethical intuitions across a wide range of research and public health ethics.

“邪恶”问题的特点是难以处理的复杂性、不确定性和个人或机构之间的冲突,它们几乎存在于医学伦理学的每个角落。尽管同样的伦理原则被广泛接受,但我们对如何表述这些问题、如何解决这些问题、什么才算解决这些问题,甚至可能的解决方案是什么,都存在分歧。也就是说,我们并不总是知道如何在混乱的现实环境中最好地实现道德理想。我勾勒了一个医学伦理学的实施框架,可以帮助澄清邪恶的问题,并组织进一步的伦理学研究来解决这些问题。该框架描述了与实质性伦理理想一起工作的程序变量,以在复杂的现实世界情况下提供伦理决策。以有争议的转基因蚊子研究为例,我说明了变量之间的可概括关系如何阐明了研究治理的新兴伦理准则,并提供了一条途径,以一种与我们在广泛的研究和公共卫生伦理中的伦理直觉相一致的方式扩展这些准则。
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引用次数: 1
Should Digital Contact Tracing Technologies be used to Control COVID-19? Perspectives from an Australian Public Deliberation. 是否应使用数字接触追踪技术控制 COVID-19?来自澳大利亚公众讨论的观点。
IF 1.8 3区 哲学 Q2 ETHICS Pub Date : 2022-06-01 Epub Date: 2021-10-26 DOI: 10.1007/s10728-021-00441-1
Chris Degeling, Julie Hall, Jane Johnson, Roba Abbas, Shopna Bag, Gwendolyn L Gilbert

Mobile phone-based applications (apps) can promote faster targeted actions to control COVID-19. However, digital contact tracing systems raise concerns about data security, system effectiveness, and their potential to normalise privacy-invasive surveillance technologies. In the absence of mandates, public uptake depends on the acceptability and perceived legitimacy of using technologies that log interactions between individuals to build public health capacity. We report on six online deliberative workshops convened in New South Wales to consider the appropriateness of using the COVIDSafe app to enhance Australian contact tracing systems. All groups took the position (by majority) that the protections enacted in the app design and supporting legislation were appropriate. This support is contingent on several system attributes including: the voluntariness of the COVIDSafe app; that the system relies on proximity rather than location tracking; and, that data access is restricted to local public health practitioners undertaking contact tracing. Despite sustained scepticism in media coverage, there was an underlying willingness to trust Australian governing institutions such that in principle acceptance of the new contact tracing technology was easy to obtain. However, tensions between the need to prove system effectiveness through operational transparency and requirements for privacy protections could be limiting public uptake. Our study shows that informed citizens are willing to trade their privacy for common goods such as COVID-19 suppression. But low case numbers and cautionary public discourses can make trustworthiness difficult to establish because some will only do so when it can be demonstrated that the benefits justify the costs to individuals.

基于手机的应用程序(App)可以促进更快地采取有针对性的行动来控制 COVID-19。然而,数字联络追踪系统在数据安全性、系统有效性及其将侵犯隐私的监控技术正常化的潜力方面引起了关注。在没有授权的情况下,公众的接受程度取决于使用记录个人之间互动的技术来建立公共卫生能力的可接受性和可感知的合法性。我们报告了在新南威尔士州召开的六次在线审议研讨会的情况,会议旨在审议使用 COVIDSafe 应用程序加强澳大利亚接触者追踪系统是否合适。所有小组(多数)都认为应用程序设计和支持立法中颁布的保护措施是适当的。这种支持取决于几个系统属性,包括:COVIDSafe 应用程序的自愿性;系统依赖于近距离追踪而非位置追踪;以及数据访问仅限于进行接触追踪的当地公共卫生从业人员。尽管媒体报道一直持怀疑态度,但人们还是愿意相信澳大利亚的管理机构,因此原则上很容易接受新的接触者追踪技术。然而,通过操作透明度证明系统有效性的需求与隐私保护要求之间的矛盾可能会限制公众的接受程度。我们的研究表明,知情公民愿意用自己的隐私来换取 COVID-19 抑制等共同利益。但是,由于案例数量较少以及公众的谨慎论调,可信度难以建立,因为只有在能够证明对个人而言收益与成本相匹配的情况下,一些人才会这样做。
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引用次数: 0
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