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2D material graphene as a potential antidiabetic and nontoxic compound in Drosophila melanogaster 二维材料石墨烯作为一种潜在的黑腹果蝇抗糖尿病无毒化合物
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-23 DOI: 10.1007/s13204-023-02988-y
Kalpanarani Dash, Deepak kumar Panda, Kushal Yadav, Sonali Meher, Monalisa Mishra

This study explains the potential role of non-functionalized graphene produced using flash joule heating technology on Drosophila melanogaster. Several characterizations of the produced graphene were conducted via field emission-scanning electron microscopy, high-resolution transmission electron microscopy, Raman spectroscopy, and X-ray diffraction studies. After being characterized, the graphene powder was orally administered to flies at doses ranging from 0.02 to 0.5%, establishing its non-toxic properties as a prerequisite for potential therapeutic applications. Experiments such as Trypan blue and 4’,6-diamidino-2-phenylindole (DAPI) revealed that graphene causes no harm to the larval gut’s plasma membrane and nucleus. Behavioral assays such as crawling and climbing assays on larvae and adults demonstrated the non-neurotoxic nature of graphene. The high sucrose diet-induced diabetic Drosophila melanogaster model was used to study antidiabetic properties. In contrast, Gram + ve bacteria B. subtilis and Gram − ve P. aeruginosa were used to study the antibacterial properties of graphene. A better metabolic profile was evidenced after graphene treatment, including a 36% decrease in hemolymph-free glucose levels and significantly reduced lipid droplets at the highest concentration. In addition, the highest concentration of graphene treatment resulted in a 57% reduced fluorescent intensity of reactive oxygen species (ROS) produced by diabetic flies. Considering all these evidence, this study concludes that graphene’s non-toxic and antidiabetic properties can be used to mitigate the symptoms associated with Type II diabetes and obesity.

本研究解释了利用闪焦耳加热技术生产的非功能化石墨烯对黑腹果蝇的潜在作用。研究人员通过场发射扫描电子显微镜、高分辨率透射电子显微镜、拉曼光谱和 X 射线衍射研究对所制备的石墨烯进行了多项表征。经过表征后,石墨烯粉末以 0.02% 至 0.5% 的剂量口服给苍蝇服用,从而确定了其无毒特性,这是潜在治疗应用的先决条件。胰蓝和 4',6-二脒基-2-苯基吲哚(DAPI)等实验表明,石墨烯不会对幼虫肠道的质膜和细胞核造成伤害。对幼虫和成虫进行的爬行和攀爬等行为试验表明,石墨烯无神经毒性。利用高蔗糖饮食诱导的糖尿病黑腹果蝇模型研究了石墨烯的抗糖尿病特性。与此相反,研究人员使用革兰氏+Ⅴ型细菌 B. subtilis 和革兰氏-Ⅴ型细菌 P. aeruginosa 来研究石墨烯的抗菌特性。经石墨烯处理后,动物的代谢状况明显改善,包括无血红蛋白葡萄糖水平降低了 36%,最高浓度的石墨烯可显著减少脂滴。此外,最高浓度的石墨烯处理使糖尿病蝇产生的活性氧(ROS)荧光强度降低了 57%。考虑到所有这些证据,本研究得出结论:石墨烯的无毒性和抗糖尿病特性可用于减轻 II 型糖尿病和肥胖症的相关症状。
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引用次数: 0
Effect of long-length carbon nanotubes on yield, ultimate, dynamic mechanical, and thermal properties of polyamide-6 composites prepared by twin-screw extrusion 长碳纳米管对双螺杆挤压法制备的聚酰胺-6 复合材料的屈服性能、极限性能、动态机械性能和热性能的影响
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-15 DOI: 10.1007/s13204-023-02992-2
Sangita Tripathy, S. R. Dhakate, Bhanu Pratap Singh

The extraordinary physical properties of multiwalled carbon nanotubes (MWCNTs) are yet to be fully realised in polyamide-6 (PA6) nanocomposites, due to difficulty in dispersion of MWCNTs within PA6 matrix, owing to high toughness of PA6 and agglomerating properties of MWCNTs. In this study, MWCNTs of high aspect ratio prepared by chemical vapour deposition (CVD) method are melt-mixed with 0.1–0.5 parts-per-hundred ratios (phr) into PA6 matrix by twin-screw extrusion. The high shearing force of co-rotating twin-screws and intermixing of the components along the back-flow channel of extruder assured uniformly dispersed MWCNTs within PA6 system. A 30.2% rise in yield strength and an 82.6% rise in Young’s modulus were noticed for 0.1 phr MWCNTs/PA6 tensile specimens over neat PA6 specimens during tensile testing. A strain hardening behaviour was shown by neat PA6, which was persistent in all its composites containing MWCNTs. A distinct trend in storage and loss behaviour, as well as 14 °C and 11 °C rise in glass transition temperatures (Tg) in loss modulus and loss factor curves, respectively, were observed for 0.5 phr MWCNTs’ reinforcement in dynamic mechanical analysis (DMA), which indicated an effective PA6–MWCNTs interaction. The improvements in crystallization and melting temperatures, as well as crystallinity values in differential scanning calorimetry (DSC) indicated nucleating effects of MWCNTs towards stable crystallization of PA6 molecules. The shifting and rise in intensity peaks in XRD and Raman spectroscopy curves supported the reinforcing effect of MWCNTs within PA6 matrix. These nanocomposites are beneficial for fabricating high mechanical and thermal stability-required components in automobiles, aerospace, and biomedicals.

多壁碳纳米管(MWCNTs)的非凡物理性能尚未在聚酰胺-6(PA6)纳米复合材料中得到充分体现,原因是 PA6 的高韧性和 MWCNTs 的团聚特性导致 MWCNTs 难以在 PA6 基体中分散。在本研究中,通过化学气相沉积(CVD)方法制备的高纵横比 MWCNTs 以 0.1-0.5 的百份比(phr)通过双螺杆挤压熔融混合到 PA6 基体中。同向旋转双螺杆的高剪切力和挤出机回流通道中各组分的相互混合确保了 MWCNTs 在 PA6 体系中的均匀分散。在拉伸测试过程中,与纯 PA6 试样相比,0.1 phr MWCNTs/PA6 拉伸试样的屈服强度提高了 30.2%,杨氏模量提高了 82.6%。纯 PA6 显示出应变硬化行为,而含有 MWCNT 的所有复合材料都持续存在这种行为。在动态力学分析 (DMA) 中,观察到 0.5 phr MWCNTs 增强材料的存储和损耗行为有明显的趋势,损耗模量和损耗因子曲线的玻璃化转变温度 (Tg) 分别上升了 14 °C 和 11 °C,这表明 PA6-MWCNTs 之间存在有效的相互作用。在差示扫描量热法(DSC)中,结晶和熔化温度以及结晶度值均有所提高,这表明 MWCNTs 对 PA6 分子的稳定结晶具有成核作用。XRD 和拉曼光谱曲线中强度峰的移动和上升证明了 PA6 基体中 MWCNTs 的增强效应。这些纳米复合材料有利于制造汽车、航空航天和生物医学领域所需的高机械稳定性和热稳定性部件。
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引用次数: 0
Retraction Note: Synthesis, molecular docking and molecular dynamics simulation of 1,4-bis(4,5-diphenyl-1H-imidazol-2-yl) benzene as a potential inhibitor against LDHA 撤稿说明:作为潜在 LDHA 抑制剂的 1,4-双(4,5-二苯基-1H-咪唑-2-基)苯的合成、分子对接和分子动力学模拟
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-14 DOI: 10.1007/s13204-024-03029-y
Mustafa Sabri Cheyad, Alaa Hussein J. Al-qaisi, Ahmed Ahmed
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引用次数: 0
Retraction Note: Change in hospital admissions in dental diseases before and during the COVID-19 pandemic 撤稿说明:COVID-19 大流行之前和期间牙科疾病住院人数的变化
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-14 DOI: 10.1007/s13204-024-03027-0
Nadejda Beleva
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引用次数: 0
Retraction Note: The optimization efficient energy cooperative communication image transmission over WSN 撤稿说明:WSN 上的优化高效能源合作通信图像传输
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-14 DOI: 10.1007/s13204-024-03002-9
Sara Taher Abbas, Husam Jasim Mohammed, Jehan Saleh Ahmed, Ameer Sardar Rashid, Bilal Alhayani, Ahmed Alkhayyat
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引用次数: 0
Retraction Note: Integration of Healthcare 4.0 and blockchain into secure cloud-based electronic health records systems 撤回说明:将医疗保健 4.0 和区块链整合到安全的云电子病历系统中
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-14 DOI: 10.1007/s13204-024-03007-4
Hemant B. Mahajan, Ameer Sardar Rashid, Aparna A. Junnarkar, Nilesh Uke, Sarita D. Deshpande, Pravin R. Futane, Ahmed Alkhayyat, Bilal Alhayani
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引用次数: 0
Titanium dioxide nanoparticles study on Lactuca sativa growth with cocopeat and sponge hydroponic systems 二氧化钛纳米颗粒对椰菜和海绵水培系统中乳草生长的研究
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-12 DOI: 10.1007/s13204-023-02991-3
Nurul Hazwanni Yaacub, Rabiatul Basria S. M. N. Mydin, Nur Hakimah Abu Mansor, Darren Zhong Han Sim, Sanjay Swarup, Noremeliawati Abdullah

Titanium dioxide nanoparticles (({text{TiO}}_{2})-NPs) are believed can enhance crop yield by accelerating the photosynthetic rate, infection control management, and competent catalyst for the decomposition of organic pollutants. The purpose of this research is to investigate the effect of titanium dioxide nanoparticles (({text{TiO}}_{2})-NPs) on L. sativa, lettuce growth in a hydroponic system using two different media: sponge and cocopeat. Hydroponic systems with optimum treatment factors, such as air temperature, humidity, light, pH of nutrient solution, and electrical conductivity (EC), were applied in this study to attain elevated yields within a short period of time. The results show that L. sativa without ({text{TiO}}_{2})-NPs treatment produces an optimum growth pattern in terms of biomass, including fresh weight, dry weight, and height, with p < 0.05, especially when using cocopeat medium. Detailed observation found that ({text{TiO}}_{2})-NPs treatment showed no significant difference between the leaf count and diameter on L. sativa. This study found that ({text{TiO}}_{2})-NPs could act as an efficient organic catalyst for maintaining hydroponic nutrient quality. However, further findings indicate that ({text{TiO}}_{2})-NPs could interfere with the nutrient absorption process from the roots, which might lead to off-color foliage, and plant stress. Further research is recommended to study the implication of ({text{TiO}}_{2})-NPs on growth, nutrient absorption, and organic catalyst potential that is beneficial for plant growth.

二氧化钛纳米颗粒(Titanium dioxide nanoparticles,简称 "纳米钛")被认为可以通过加速光合速率、控制感染管理和分解有机污染物的催化剂来提高作物产量。本研究的目的是利用海绵和椰糠两种不同的培养基,研究二氧化钛纳米粒子(({text{TiO}}_{2}/)-NPs)对水培系统中莴苣生长的影响。本研究采用的水培系统具有最佳处理因素,如空气温度、湿度、光照、营养液 pH 值和导电率(EC),可在短时间内提高产量。研究结果表明,未经 ({text{TiO}}_{2})-NPs 处理的荠菜在生物量(包括鲜重、干重和高度)方面产生了最佳生长模式,p < 0.05,尤其是在使用椰糠培养基时。详细观察发现,({text{TiO}}_{2}/)-NPs 处理对荠菜的叶片数量和直径没有显著差异。这项研究发现,({text{TiO}}_{2}/)-NPs 可以作为一种有效的有机催化剂来维持水培营养液的质量。然而,进一步的研究结果表明,({text{TiO}}_{2}/)-NPs 可能会干扰根系吸收养分的过程,从而可能导致叶片失色和植物胁迫。建议进一步研究({text{TiO}}_{2}/)-NPs 对植物生长、养分吸收和有机催化剂潜力的影响。
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引用次数: 0
Retraction Note to: An efficient technique to PAPR reduction for LTE uplink using Lonzo’s resampling technique in both SC-LFDMA and SC-DFDMA systems 撤回说明:在 SC-LFDMA 和 SC-DFDMA 系统中使用 Lonzo 的重采样技术降低 LTE 上行链路 PAPR 的有效技术
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-11 DOI: 10.1007/s13204-024-03008-3
Tahreer Mahmood, Omar Abdulkareem Mahmood, Khalid Awaad Humood
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引用次数: 0
Retraction Note: Passive islanding detection in microgrids using artificial neural networks 撤稿说明:利用人工神经网络在微电网中进行被动孤岛检测
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-11 DOI: 10.1007/s13204-024-03004-7
Ali Majeed Mohammed Alyasiri, Sefer Kurnaz
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引用次数: 0
Retraction Note: Study the influence of using guide vanes blades on the performance of cross-flow wind turbine 撤稿说明:研究使用导叶叶片对贯流式风力发电机性能的影响
IF 3.674 4区 工程技术 Q1 Engineering Pub Date : 2024-01-11 DOI: 10.1007/s13204-024-03019-0
Waled Yahya, Kou Ziming, Wu Juan, Mohammed Al-Nehari, Li Tengyu, Ren Qichao, Bilal Alhayani
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引用次数: 0
期刊
Applied Nanoscience
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