Pub Date : 2023-09-22DOI: 10.18500/1819-7671-2023-23-3-244-248
Оleg D. Agapov, Eleonora I. Agapova
Introduction. The main idea of the article is that every established educational strategy combines the incompatible, generating economocentrism, political centrism, technocentrism, ecocentrism and other “centrisms” that lead to a reductivist approach to the meaning and forms of education. Theoretical analysis. Education as a socioanthropological institution is relatively autonomous, and the idea of autopoiesis of the human being is what lies at the foundation of its autonomy. In this context, philosophy of education appears as a philosophy of its age, or, even broader, a philosophy of human beings who are able not only to integrate themselves into the civilizational design of the epoch with its cultural and historical standards, and professional needs, but also to transcend their epoch in search for themselves / their own. Empirical analysis. The inalienable mission of education consists in creating a social field for spiritual maturation and self-perfection for individual human beings. Education acquires its completeness and dignity only when it reaches the level of navigating a person towards development, “the care of the self”. Conclusion. Education thus becomes a form of development of a civil society, able to self-organize and self-develop, to create (cultivating meanings and institutions), which is not reducible to a social “conveyor-factory” for producing semi-finished products according to the standards of political, professional or sociocultural institutions.
{"title":"Combining the incompatible, or on the question of the synergy of educational strategies","authors":"Оleg D. Agapov, Eleonora I. Agapova","doi":"10.18500/1819-7671-2023-23-3-244-248","DOIUrl":"https://doi.org/10.18500/1819-7671-2023-23-3-244-248","url":null,"abstract":"Introduction. The main idea of the article is that every established educational strategy combines the incompatible, generating economocentrism, political centrism, technocentrism, ecocentrism and other “centrisms” that lead to a reductivist approach to the meaning and forms of education. Theoretical analysis. Education as a socioanthropological institution is relatively autonomous, and the idea of autopoiesis of the human being is what lies at the foundation of its autonomy. In this context, philosophy of education appears as a philosophy of its age, or, even broader, a philosophy of human beings who are able not only to integrate themselves into the civilizational design of the epoch with its cultural and historical standards, and professional needs, but also to transcend their epoch in search for themselves / their own. Empirical analysis. The inalienable mission of education consists in creating a social field for spiritual maturation and self-perfection for individual human beings. Education acquires its completeness and dignity only when it reaches the level of navigating a person towards development, “the care of the self”. Conclusion. Education thus becomes a form of development of a civil society, able to self-organize and self-develop, to create (cultivating meanings and institutions), which is not reducible to a social “conveyor-factory” for producing semi-finished products according to the standards of political, professional or sociocultural institutions.","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1817-3020-2023-23-3-198-208
A. A. Koronovskii, M. K. Kurovskaya, O. I. Moskalenko
.
{"title":"Synchronization in phase oscillator networks with “ring” and “small world” link topologies and different dependences of the oscillator frequency on its network location","authors":"A. A. Koronovskii, M. K. Kurovskaya, O. I. Moskalenko","doi":"10.18500/1817-3020-2023-23-3-198-208","DOIUrl":"https://doi.org/10.18500/1817-3020-2023-23-3-198-208","url":null,"abstract":".","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136099615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1819-7671-2023-23-3-249-253
Valentina A. Andreeva
Introduction. The image of a woman helps to construct one’s understanding of the world, relations in society, ideas about the Other. This article is devoted to a critical analysis of the transformation of the image of a woman in a network society. Theoretical analysis. Today, the position of rejecting gender differences, which serve as one of the sources of human culture, is increasing in society. A crisis situation arises, accompanied by the loss of gender self-identification, the violation of internalization and existential frustration. In the network image of society, women are polyvariant and solve it by interpreting the actor who uses it, but a person acquires and manifests his or her generic essence only in the intuitions of the social essence, with the help of transcending. Conclusion. We come to the conclusion that the image of a woman in a network society is constructed by means of a pseudo-democratic mythologeme, which implements the illusion of freedom and leads to the full autonomy of individuals, which is the cause of alienating a person from society and thereby from himself/herself. The proposed way out of the existing gender identity crisis is by means of transcending communication, which includes signification.
{"title":"The image of a woman in the conditions of modern pseudo-democratic mythology","authors":"Valentina A. Andreeva","doi":"10.18500/1819-7671-2023-23-3-249-253","DOIUrl":"https://doi.org/10.18500/1819-7671-2023-23-3-249-253","url":null,"abstract":"Introduction. The image of a woman helps to construct one’s understanding of the world, relations in society, ideas about the Other. This article is devoted to a critical analysis of the transformation of the image of a woman in a network society. Theoretical analysis. Today, the position of rejecting gender differences, which serve as one of the sources of human culture, is increasing in society. A crisis situation arises, accompanied by the loss of gender self-identification, the violation of internalization and existential frustration. In the network image of society, women are polyvariant and solve it by interpreting the actor who uses it, but a person acquires and manifests his or her generic essence only in the intuitions of the social essence, with the help of transcending. Conclusion. We come to the conclusion that the image of a woman in a network society is constructed by means of a pseudo-democratic mythologeme, which implements the illusion of freedom and leads to the full autonomy of individuals, which is the cause of alienating a person from society and thereby from himself/herself. The proposed way out of the existing gender identity crisis is by means of transcending communication, which includes signification.","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1816-9775-2023-23-3-280-288
Raisa I. Kuzmina, Raushan N. Kubasheva, Zaripa Kh. Kunasheva
This article presents the results of the thermal processing of sludge from domestic wastewater under laboratory conditions. The pyrolysis process is carried out in a batch reactor with an original design. Gaseous and liquid forms of hydrocarbon compounds, as well as solid carbonaceous residue, were obtained after processing the sludge in a pyrolytic plant. It is established that during pyrolysis of sludge sewage sludge, the output of the process products depends on the heating rate of the raw material. The results of chromatographic, X-ray diffraction, spectroscopic studies of the composition, properties, and structure of pyrolysis products are presented in the following sections. This research project involved the analysis of sludge sediment samples obtained from different locations within the oil and gas field of the West Kazakhstan region. The results of the chemical analysis of the initial sludge (pH of the water extract, cationic-anionic composition, determination of organic matter in the sample) selected from several points of the sludge site are presented. Differential thermal analysis of silt sediments has been carried out. The results of this study demonstrate that the pyrolysis of sludge leads to thermal sterilization and the production of gaseous, liquid, and solid carbonaceous residue, which exhibit potential as fuel sources or raw materials for petrochemical synthesis. In addition, heavy metals (such as mercury and cadmium) can be separated from the carbonaceous residue during pyrolysis. It is proposed to use the solid pyrolysis sludge as a sorbent for the collection of oil and petroleum products, as it is economically and environmentally beneficial.
{"title":"Investigation of the properties of the solid residue of the pyrolysis of sewage sludge","authors":"Raisa I. Kuzmina, Raushan N. Kubasheva, Zaripa Kh. Kunasheva","doi":"10.18500/1816-9775-2023-23-3-280-288","DOIUrl":"https://doi.org/10.18500/1816-9775-2023-23-3-280-288","url":null,"abstract":"This article presents the results of the thermal processing of sludge from domestic wastewater under laboratory conditions. The pyrolysis process is carried out in a batch reactor with an original design. Gaseous and liquid forms of hydrocarbon compounds, as well as solid carbonaceous residue, were obtained after processing the sludge in a pyrolytic plant. It is established that during pyrolysis of sludge sewage sludge, the output of the process products depends on the heating rate of the raw material. The results of chromatographic, X-ray diffraction, spectroscopic studies of the composition, properties, and structure of pyrolysis products are presented in the following sections. This research project involved the analysis of sludge sediment samples obtained from different locations within the oil and gas field of the West Kazakhstan region. The results of the chemical analysis of the initial sludge (pH of the water extract, cationic-anionic composition, determination of organic matter in the sample) selected from several points of the sludge site are presented. Differential thermal analysis of silt sediments has been carried out. The results of this study demonstrate that the pyrolysis of sludge leads to thermal sterilization and the production of gaseous, liquid, and solid carbonaceous residue, which exhibit potential as fuel sources or raw materials for petrochemical synthesis. In addition, heavy metals (such as mercury and cadmium) can be separated from the carbonaceous residue during pyrolysis. It is proposed to use the solid pyrolysis sludge as a sorbent for the collection of oil and petroleum products, as it is economically and environmentally beneficial.","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1819-7671-2023-23-3-303-307
Karina M. Gaidar
Introduction. The problem of the peculiarities of the work of organizational psychologists in the conditions of a special military operation (SMO) and after its completion is raised. The similarity of the existential meanings of the Great Patriotic War and the SMO and the differences in the socio-psychological processes that accompany them are revealed. Theoretical analysis. It is argued that while maintaining traditional tasks, but changing the conditions for their solution, the content of the activities of organizational psychologists undergoes transformations that can become even more pronounced after the end of the SMO. New socio-psychological contexts lead to different emphases in the work of organizational psychologists. In particular, on the basis of analysis of the tasks of organizational psychology and current practical experience, new emphasis has been identified in such areas of work of psychologists in organizations as the preservation of organizational culture and the cohesion of work teams, the psychological support of workers, the formation of their psychological readiness for constructive interaction with participants in the SMO after their return to civilian life, advising the latter on their requests. Conclusion. As a result of the analysis, a position was formulated on the need to pay increased attention to the training of organizational psychologists to work in new conditions, to solve the problem of quantitative and qualitative support for this training.
{"title":"Organizational psychology in the conditions of a special military operation and afterwards: Old tasks, new contexts and emphasis","authors":"Karina M. Gaidar","doi":"10.18500/1819-7671-2023-23-3-303-307","DOIUrl":"https://doi.org/10.18500/1819-7671-2023-23-3-303-307","url":null,"abstract":"Introduction. The problem of the peculiarities of the work of organizational psychologists in the conditions of a special military operation (SMO) and after its completion is raised. The similarity of the existential meanings of the Great Patriotic War and the SMO and the differences in the socio-psychological processes that accompany them are revealed. Theoretical analysis. It is argued that while maintaining traditional tasks, but changing the conditions for their solution, the content of the activities of organizational psychologists undergoes transformations that can become even more pronounced after the end of the SMO. New socio-psychological contexts lead to different emphases in the work of organizational psychologists. In particular, on the basis of analysis of the tasks of organizational psychology and current practical experience, new emphasis has been identified in such areas of work of psychologists in organizations as the preservation of organizational culture and the cohesion of work teams, the psychological support of workers, the formation of their psychological readiness for constructive interaction with participants in the SMO after their return to civilian life, advising the latter on their requests. Conclusion. As a result of the analysis, a position was formulated on the need to pay increased attention to the training of organizational psychologists to work in new conditions, to solve the problem of quantitative and qualitative support for this training.","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1817-3020-2023-23-3-209-220
I. N. Mikhailov, Y. V. Nikulin, S. S. Volchkov, M. Yu. Vasilkov, N. A. Malofeeva, I. D. Kosobudsky, N. M. Ushakov
{"title":"Optical spectroscopy of nanoporous membranes based on anodic alumina in an ammonia gas flow","authors":"I. N. Mikhailov, Y. V. Nikulin, S. S. Volchkov, M. Yu. Vasilkov, N. A. Malofeeva, I. D. Kosobudsky, N. M. Ushakov","doi":"10.18500/1817-3020-2023-23-3-209-220","DOIUrl":"https://doi.org/10.18500/1817-3020-2023-23-3-209-220","url":null,"abstract":"","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136099616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1816-9775-2023-23-3-331-336
Nikita M. Poverenniy, Vasily V. Anikin
The taxonomy of scorpions belonging to the genus Mesobuthus has undergone significant revisions in recent times. Initially, based on the morphological characteristics, scientists identified and described a considerable number of subspecies within different species of this genus. However, in the last decade, modern researchers have “revised” the species diversity of the genus based on the results of genetic and morphological analyses, forming new separate species complexes. As a result, a species complex called “Mesobuthus caucasicus” was identified, which was later reassigned to the genus Olivierus by František Kovařík in 2019. Currently, the genus Olivierus comprises 18 species, with 7 of them inhabiting the territory of Central Asia. The distribution ranges of most Central Asian species of the genus Olivierus overlap with those of the genus Mesobuthus. Specifically, in the territory of the Republic of Kazakhstan, the species Olivierus gorelovi occurs, whose distribution range coincides with that of Mesobuthus thersites. Due to this overlap, the taxonomic status of some scorpion populations inhabiting the territory of the Republic of Kazakhstan remains uncertain and poorly studied. The authors of this study attempted to determine the phylogenetic relationships among individuals from different populations using data obtained from molecular genetic barcoding. The analysis was conducted on three nuclear and one mitochondrial gene fragments of scorpions inhabiting the regions of Zhambyl, Karaganda, Atyrau, Turkestan, Abay, and Almaty. The obtained results indicate that scorpions of the genus Olivierus inhabit the territories of Atyrau, Almaty, Karaganda, and Turkestan regions, while scorpions of the genus Mesobuthus inhabit the territories of Zhambyl, Karaganda, and Abay regions. This study makes a direct contribution to the study of scorpion fauna biodiversity in Central Asia.
{"title":"Phylogenetic analysis of scorpions of the genus Mesobuthus (Vachon, 1950), inhabiting the territory of Kazakhstan, based on the analysis of fragments of mitochondrial and nuclear genes.","authors":"Nikita M. Poverenniy, Vasily V. Anikin","doi":"10.18500/1816-9775-2023-23-3-331-336","DOIUrl":"https://doi.org/10.18500/1816-9775-2023-23-3-331-336","url":null,"abstract":"The taxonomy of scorpions belonging to the genus Mesobuthus has undergone significant revisions in recent times. Initially, based on the morphological characteristics, scientists identified and described a considerable number of subspecies within different species of this genus. However, in the last decade, modern researchers have “revised” the species diversity of the genus based on the results of genetic and morphological analyses, forming new separate species complexes. As a result, a species complex called “Mesobuthus caucasicus” was identified, which was later reassigned to the genus Olivierus by František Kovařík in 2019. Currently, the genus Olivierus comprises 18 species, with 7 of them inhabiting the territory of Central Asia. The distribution ranges of most Central Asian species of the genus Olivierus overlap with those of the genus Mesobuthus. Specifically, in the territory of the Republic of Kazakhstan, the species Olivierus gorelovi occurs, whose distribution range coincides with that of Mesobuthus thersites. Due to this overlap, the taxonomic status of some scorpion populations inhabiting the territory of the Republic of Kazakhstan remains uncertain and poorly studied. The authors of this study attempted to determine the phylogenetic relationships among individuals from different populations using data obtained from molecular genetic barcoding. The analysis was conducted on three nuclear and one mitochondrial gene fragments of scorpions inhabiting the regions of Zhambyl, Karaganda, Atyrau, Turkestan, Abay, and Almaty. The obtained results indicate that scorpions of the genus Olivierus inhabit the territories of Atyrau, Almaty, Karaganda, and Turkestan regions, while scorpions of the genus Mesobuthus inhabit the territories of Zhambyl, Karaganda, and Abay regions. This study makes a direct contribution to the study of scorpion fauna biodiversity in Central Asia.","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136099792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1816-9775-2023-23-3-272-279
Ilya V. Vnukov, Egor A. Ashikhmin, Svetlana B. Romadenkina, Tatiana V. Aniskova
The production of various motor fuels is carried out by processing light fractions of oil with an initial temperature of boiling to 350°С. The current trend shows that oil in new fields has more weight than before. New oil reservoirs are deeper with a greater proportion of dark fraction with a boiling point of 350°С. This situation stimulates to find new ways of increasing the processing depth light fractions for synthesis target product. One of the main solution path for the problem is creation of new catalytic systems or modernization of existing ones. Motor fuels must meet the necessary operational and environmental characteristics, which is determined by their chemical composition. This article is devoted to the study of bifunctional catalyzers for the conversion of n-hexane. High molecular zeolite CVM (ZSM-5) was used as a carrier, which has functionality due to the presence of various active centers. Platinum (Pt/CVM), praseodymium (Pr/CVM) were also applied to the carrier, and praseodymium and platinum (Pt,Pr/CVM) were successively applied by impregnation. Normal hexane was used as a raw material. The choice of this raw material is associated with the ability to aromatization reaction, as well as the presence of n-hexane in the raw materials of the process of obtaining motor fuels-catalytic reforming. As a result of the transformation of raw materials, liquid fuel of multicomponent composition with the number of carbon atoms in the chain from 3 to 14, as well as gases containing C1 – C5 hydrocarbons, was obtained. When n-hexane is converted on the catalyzers under study, both the octane number and the content of aromatic hydrocarbons increase with increasing temperature. It has been found that when the process is carried out at a temperature of 450°C, the highest yield of the catalysate is (33.8% by weight.) on a Pt,Pr/CVM catalyzer. With an increase in temperature, the yield of benzene increases. Minimum benzene yield (0.6 wt. %) is achieved at 450°C marked by a bimetallic catalyzer, which corresponds to the EURO-5 gasoline standard. The highest degree of conversion was observed during the conversion of n-hexane on the Pt,Pr/CMC catalytic system at a temperature of 450° C, which was (97%).
{"title":"Study of the activity of bifunctional catalyzers on the transformation of n-hexane","authors":"Ilya V. Vnukov, Egor A. Ashikhmin, Svetlana B. Romadenkina, Tatiana V. Aniskova","doi":"10.18500/1816-9775-2023-23-3-272-279","DOIUrl":"https://doi.org/10.18500/1816-9775-2023-23-3-272-279","url":null,"abstract":"The production of various motor fuels is carried out by processing light fractions of oil with an initial temperature of boiling to 350°С. The current trend shows that oil in new fields has more weight than before. New oil reservoirs are deeper with a greater proportion of dark fraction with a boiling point of 350°С. This situation stimulates to find new ways of increasing the processing depth light fractions for synthesis target product. One of the main solution path for the problem is creation of new catalytic systems or modernization of existing ones. Motor fuels must meet the necessary operational and environmental characteristics, which is determined by their chemical composition. This article is devoted to the study of bifunctional catalyzers for the conversion of n-hexane. High molecular zeolite CVM (ZSM-5) was used as a carrier, which has functionality due to the presence of various active centers. Platinum (Pt/CVM), praseodymium (Pr/CVM) were also applied to the carrier, and praseodymium and platinum (Pt,Pr/CVM) were successively applied by impregnation. Normal hexane was used as a raw material. The choice of this raw material is associated with the ability to aromatization reaction, as well as the presence of n-hexane in the raw materials of the process of obtaining motor fuels-catalytic reforming. As a result of the transformation of raw materials, liquid fuel of multicomponent composition with the number of carbon atoms in the chain from 3 to 14, as well as gases containing C1 – C5 hydrocarbons, was obtained. When n-hexane is converted on the catalyzers under study, both the octane number and the content of aromatic hydrocarbons increase with increasing temperature. It has been found that when the process is carried out at a temperature of 450°C, the highest yield of the catalysate is (33.8% by weight.) on a Pt,Pr/CVM catalyzer. With an increase in temperature, the yield of benzene increases. Minimum benzene yield (0.6 wt. %) is achieved at 450°C marked by a bimetallic catalyzer, which corresponds to the EURO-5 gasoline standard. The highest degree of conversion was observed during the conversion of n-hexane on the Pt,Pr/CMC catalytic system at a temperature of 450° C, which was (97%).","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1816-9775-2023-23-3-345-355
Marina V. Parchaykina, Tatyana P. Kuzmenko, Elena V. Chudaikina, Maria Yu. Gladysheva, Elvira S. Revina, Viktor V. Revin
The content of neurotrophic factors in damaged somatic nerves under the action of the drug «Semax» was studied and their role in the regulation of regenerative processes in injured nerve conductors was established. It has been shown that intramuscular administration of the drug is accompanied by a significant increase in the level of NGF and NT-3 both in the proximal and distal parts of the nerve. At the same time, there are no significant changes in the quantitative content of neuroregulin-1 against the background of its use. The data obtained suggest that one of the mechanisms of action of Semax is its ability to interact with Schwann cells and stimulate the release of NGF and NT-3, which facilitate the regeneration of damaged axons and do not affect the synthesis of neuroregulin-1. In addition, the study of the quantitative content of individual protein fractions showed that the drug «Semax» has the most pronounced effect on the level of neurofilament-H in both segments of the nerve conductor, which indicates the important role and activation of the mitogen-activated protein kinase (MAPK / ERK) signalling pathway, which regulates processes of cytoskeletal protein synthesis and axon growth. Nevertheless, it was shown that in the variant of the experiment using Semax, there was a decrease in the level of GAP-43, which is a key marker of axonal growth, both in the proximal and distal segments of the nerve. The data obtained most likely indicate that the intramuscular administration of the drug does not affect the processes of axon growth, but is aimed at maintaining the survival of neurons and accelerated restoration of the functional state of nerve fibres, which is also confirmed by the appearance of an action potential and the ability of the nerve to conduct it against the background of the use of the Semax drug.
{"title":"Study of the role of neurotrophic factors in the regulation of regeneration processes in damaged somatic nerves under the action of semax peptide preparation","authors":"Marina V. Parchaykina, Tatyana P. Kuzmenko, Elena V. Chudaikina, Maria Yu. Gladysheva, Elvira S. Revina, Viktor V. Revin","doi":"10.18500/1816-9775-2023-23-3-345-355","DOIUrl":"https://doi.org/10.18500/1816-9775-2023-23-3-345-355","url":null,"abstract":"The content of neurotrophic factors in damaged somatic nerves under the action of the drug «Semax» was studied and their role in the regulation of regenerative processes in injured nerve conductors was established. It has been shown that intramuscular administration of the drug is accompanied by a significant increase in the level of NGF and NT-3 both in the proximal and distal parts of the nerve. At the same time, there are no significant changes in the quantitative content of neuroregulin-1 against the background of its use. The data obtained suggest that one of the mechanisms of action of Semax is its ability to interact with Schwann cells and stimulate the release of NGF and NT-3, which facilitate the regeneration of damaged axons and do not affect the synthesis of neuroregulin-1. In addition, the study of the quantitative content of individual protein fractions showed that the drug «Semax» has the most pronounced effect on the level of neurofilament-H in both segments of the nerve conductor, which indicates the important role and activation of the mitogen-activated protein kinase (MAPK / ERK) signalling pathway, which regulates processes of cytoskeletal protein synthesis and axon growth. Nevertheless, it was shown that in the variant of the experiment using Semax, there was a decrease in the level of GAP-43, which is a key marker of axonal growth, both in the proximal and distal segments of the nerve. The data obtained most likely indicate that the intramuscular administration of the drug does not affect the processes of axon growth, but is aimed at maintaining the survival of neurons and accelerated restoration of the functional state of nerve fibres, which is also confirmed by the appearance of an action potential and the ability of the nerve to conduct it against the background of the use of the Semax drug.","PeriodicalId":476403,"journal":{"name":"Izvestiâ Saratovskogo universiteta. Novaâ seriâ","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136100499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-22DOI: 10.18500/1819-7671-2023-23-3-272-276
Alexey V. Muratov
Introduction. The article discusses the view on social justice through the prism of the philosophy of Islam, the problem of its study and analysis, from the perspective of explanation and interpretation of sacred texts. The theoretical social base laid down in the Koran and the Sunnah, as well as the social model built during the reign of the four “righteous caliphs” are analyzed. To illustrate the application of the basic methods of Islamic theology to questions of social philosophy, some concrete examples are given. Theoretical analysis. The conducted comparative analysis allows us to conclude that there is a carefully developed theoretical base regulating the issues of social justice in Islam, the need to use a legitimate methodology and tools based on it in deriving certain social norms in order to avoid speculative judgments. Conclusion. The result of this study is the conclusion about the universality of the principles of social justice in the philosophy of Islam, the importance of studying its social function. In this regard the original model laid down in its primary sources is taken as a standard. As an exception to the risks of transformation caused by the influence on Muslim societies of various socio-philosophical, political and other ideas that did not come out of its foundations, it is necessary to consistently apply a certain methodology for analyzing Islamic doctrines.
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