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Interpersonal emotion regulation and mental health among cancer survivors: A systematic review 癌症幸存者的人际情绪调节与心理健康:系统回顾
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100592
Zihao Zeng , Karen Holtmaat , Xihan Jia , George L. Burchell , Sander L. Koole , Irma M. Verdonck- de Leeuw

Objective

Cancer and its treatment can cause significant emotional distress, adversely affecting mental health. Interpersonal emotion regulation, the process by which individuals regulate emotions through social interactions, plays a critical role in cancer survivorship. This study systematically reviews evidence on the associations between interpersonal emotion regulation and mental health outcomes among cancer survivors, along with the theoretical models guiding this research.

Methods

A systematic search was conducted in PubMed, Embase, Web of Science, and Scopus databases, yielding 6928 records. After applying inclusion and exclusion criteria, 86 studies involving 67,592 cancer survivors were included. Various aspects of interpersonal emotion regulation (e.g., emotional support, social constraints, affectionate support) and mental health indicators (e.g., depression, anxiety, quality of life) were evaluated. Quality assessments and data synthesis were performed in accordance with PRISMA guidelines.

Results

Interpersonal emotion regulation was consistently associated with mental health outcomes. Emotional support, affectionate support, and dyadic coping showed small-to-moderate positive associations with improved mental health (e.g., reduced depression, anxiety, and distress, and enhanced quality of life). Conversely, social constraints and ambivalence over emotional expression were negatively associated with mental health. Less than one-third of studies referenced theoretical models, the most frequent being the social-cognitive processing model and the stress-buffering hypothesis.

Conclusion

Interpersonal emotion regulation significantly influences mental health among cancer survivors, with distinct strategies yielding varying impacts. Future research should integrate theoretical frameworks and longitudinal designs to better elucidate causal mechanisms and optimize interventions targeting interpersonal dynamics in survivorship care.
癌症及其治疗可引起严重的情绪困扰,对心理健康产生不利影响。人际情绪调节,即个体通过社会互动调节情绪的过程,在癌症生存中起着关键作用。本研究系统地回顾了癌症幸存者人际情绪调节与心理健康结果之间关系的证据,以及指导本研究的理论模型。方法系统检索PubMed、Embase、Web of Science、Scopus等数据库,得到6928条记录。在应用纳入和排除标准后,纳入了86项研究,涉及67,592名癌症幸存者。评估了人际情绪调节的各个方面(如情感支持、社会约束、情感支持)和心理健康指标(如抑郁、焦虑、生活质量)。根据PRISMA指南进行质量评估和数据综合。结果人际情绪调节与心理健康结果一致。情感支持、深情支持和二元应对与改善心理健康(例如,减少抑郁、焦虑和痛苦,提高生活质量)显示出小到中度的正相关。相反,社会约束和情绪表达的矛盾心理与心理健康呈负相关。不到三分之一的研究引用了理论模型,最常见的是社会认知加工模型和压力缓冲假说。结论人际情绪调节对癌症幸存者的心理健康有显著影响,不同的调节策略产生不同的影响。未来的研究应结合理论框架和纵向设计,以更好地阐明因果机制,优化针对生存护理中人际动态的干预措施。
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引用次数: 0
Sleep disturbances in early adolescents and risk of later suicidality: A national prospective cohort study 青少年早期睡眠障碍与后期自杀风险:一项全国前瞻性队列研究
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100580
Martin Ekholm Michelsen , Annette Erlangsen , Nikolaj Kjær Høier , Poul Jørgen Jennum , Merete Nordentoft , Trine Madsen

Introduction

Sleep disturbances have been linked to later suicidality among adolescents. This study assessed the associations between sleep disturbances experienced at age 11 and the subsequent occurrence of suicide thoughts and suicide attempt measured at age 18.

Methods

Self-reported data on sleep disturbances measured at age 11 was obtained from the Danish National Birth Cohort and linked to information on suicidality at age 18 based on self-reports and register-based data on hospital contacts for suicide attempt. Relative risk ratios(RRR) with corresponding 95 % confidence intervals were estimated using multivariable multinomial logistic regressions adjusting for sex, sociodemographic characteristics, psychiatric history, and child risk behaviors and procedures of inverse probability weighting were applied .

Results

A total of 28,251 participants were included, of whom 8894 (32.0 %) reported suicide thoughts and 743 (3.3 %) attempted suicide at age 18. Adolescents who at age 11 reported sleeping <8 hours per night had elevated risk of suicide thoughts (aRRR, 1.7; 95 % CI, 1.3–2.1) and suicide attempt (aRRR, 3.7; 95 % CI, 2.6–5.4) when compared with those sleeping ≥9 hours. Going to bed after 10:30PM versus before 9:00PM on weekdays was associated with higher risks of suicide thoughts (aRRR, 1.6; 95 % CI, 1.3–2.0) and suicide attempt (aRRR, 3.3; 95 % CI, 2.3–4.9). Dose-response relationships documented that experiencing difficulties falling asleep more often was associated with higher risks of suicide thoughts and suicide attempts. Adjusting for child psychiatric co-morbidity attenuated results, however associations still showed statistical significance.

Conclusion

Sleep disturbances were associated with later suicidality among adolescents. Significant associations suggested that adequate hours of sleep and earlier bedtimes might protect against suicidality in children and adolescents.
在青少年中,睡眠障碍与后来的自杀行为有关。这项研究评估了11岁时经历的睡眠障碍与随后18岁时自杀念头和自杀企图之间的联系。方法从丹麦国家出生队列中获得11岁时测量的自我报告的睡眠障碍数据,并将其与18岁时基于自我报告和自杀未遂医院联系记录的自杀信息联系起来。采用多变量多项式logistic回归,对性别、社会人口学特征、精神病史、儿童危险行为等因素进行校正,估算出相应95%置信区间的相对风险比(RRR)。结果共纳入28,251名参与者,其中8894名(32.0%)报告有自杀念头,743名(3.3%)在18岁时自杀未遂。11岁时报告每晚睡8小时的青少年有更高的自杀念头风险(aRRR, 1.7;95% CI, 1.3-2.1)和自杀企图(aRRR, 3.7;95% CI, 2.6-5.4),与睡眠时间≥9小时者相比。在工作日晚上10:30之后上床睡觉与晚上9:00之前相比,自杀念头的风险更高(aRRR, 1.6;95% CI, 1.3-2.0)和自杀企图(aRRR, 3.3;95% ci, 2.3-4.9)。剂量-反应关系表明,入睡困难的频率越高,自杀念头和自杀企图的风险越高。对儿童精神疾病合并症进行调整后,结果减弱,但相关仍显示有统计学意义。结论睡眠障碍与青少年后期自杀行为有关。重要的关联表明,充足的睡眠时间和较早的就寝时间可以防止儿童和青少年自杀。
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引用次数: 0
Extended childhood disorder (ECD): Proposal and preliminary empirical support for a new ecologically-based diagnostic category of teen dysfunction 延长儿童障碍(ECD):建议和初步经验支持一个新的基于生态学的青少年功能障碍诊断类别
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100572
Robert Epstein, Savannah Aries, Theodore T. Caligiuri, Camille Karner

Background/Objective

Existing diagnostic categories of teen dysfunction often refer to hypothetical biological or developmental factors, even though teen dysfunction is often absent in many non-Western cultures. Diagnostic categories of this sort do not do justice to the social causes of many teen problems in the United States (U.S.) and other Western countries. To put more emphasis on known cultural causes of teen dysfunction, we propose adopting an ecologically-based diagnostic category we call “extended childhood disorder” (ECD), characterized by (1) excessive and sometimes harmful involvement with peers, (2) conflict centering around control issues with authority figures, and (3) mood problems centering around control issues with authority figures.

Method

5198 individuals were evaluated, either by themselves or by therapists, counselors, teachers, or parents: a diverse group of 3147 females, 1750 males, and 301 others, mean age 23.4. 54.3 % of the participants were from the U.S., and the remaining 46.7 % were English speakers in 74 other countries.

Results

Total scores on a diagnostic test of ECD were negatively correlated with level of happiness and positively correlated with levels of anger, depression, and anxiety, whether reported by self or others (note that higher scores on the ECDI indicate greater dysfunction). Total scores were also predictive of 13 clinically significant criterion variables. Notably, prevalence of ECD in our sample roughly matched the 2010 National Comorbidity Survey estimates of the prevalence of teen disorders in the U.S.

Conclusion

The ECD diagnostic category should be considered as a viable alternative to current diagnoses of teen problems that emphasize hypothetical endemic or neural deficits.
背景/目的尽管青少年功能障碍在许多非西方文化中通常不存在,但现有的青少年功能障碍诊断类别通常是指假设的生物学或发育因素。在美国和其他西方国家,这种类型的诊断分类并不能公正地对待许多青少年问题的社会原因。为了更加强调已知的青少年功能障碍的文化原因,我们建议采用一种基于生态学的诊断类别,我们称之为“扩展儿童障碍”(ECD),其特征是:(1)过度的,有时有害的同伴参与,(2)围绕权威人物的控制问题的冲突,以及(3)围绕权威人物的控制问题的情绪问题。方法对5198名个体进行了评估,包括他们自己或治疗师、咨询师、老师或家长:3147名女性、1750名男性和301名其他人群,平均年龄23.4岁。54.3%的参与者来自美国,剩下的46.7%来自其他74个国家的说英语的人。结果ECD诊断测试的总分与幸福水平呈负相关,与愤怒、抑郁和焦虑水平呈正相关,无论是自我报告还是他人报告(注意ECDI得分越高表明功能障碍越严重)。总分还预测了13个具有临床意义的标准变量。值得注意的是,在我们的样本中,ECD的患病率与2010年美国青少年疾病共病调查估计的患病率大致相符。结论:ECD诊断类别应被视为一种可行的替代方法,以替代目前强调假设的流行病或神经缺陷的青少年问题诊断。
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引用次数: 0
Impact of extreme physical exercise (28 consecutive marathons) on sleep time and structure 极限体育锻炼(连续28次马拉松)对睡眠时间和结构的影响
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100586
Gualberto Buela-Casal , Noelia Ruiz-Herrera , Alejandro Guillén-Riquelme , Carlos Zamarrón , Francisco Gude-Sampedro

Objective

It is known that physical exercise influences sleep, however, the effect in extreme sporting conditions has been less studied. We analyzed the sleep quality and duration of an athlete who ran 28 consecutive marathons (one per day).

Methods

We evaluated with three polysomnography recordings to explore the sleep-dependent recovery process: Post-marathons, partial recovery, and baseline.

Results

The participant reported a low sleep quality during the challenge, along with short sleep time, several awakenings, and daytime sleepiness. We observed differences in sleep duration, quality, and distribution in all variables evaluated through polysomnography. From baseline to the final condition after the physical test, we observed a progressive decrease in sleep time and sleep efficiency. In addition, we observed an increase in sleep onset and REM sleep latencies, a 45.8 % increase in slow wave sleep, which affects the complete sleep structure after physical exertion. REM decreased by up to 14.4 % because of intense and continuous physical exercise, and with respect to SWS (38.5 %) this represents an increase in SWS of 267 % with respect to REM.

Conclusion

sleep is affected by high-intensity physical exercise and is modulated by the recovery process. The results of this study highlight the importance of SWS in the recovery from physical fatigue due to the effect of extreme physical exercise, which is demonstrated by the enormous increase in SWS that accounts for almost 40 % of the Total Sleep Time, surpassing even the stage 2 percentage. It is also shown that REM sleep has no role in the recovery from physical fatigue, as it is in fact considerably decreased by the effect of extreme physical exercise. Previous studies had not reported results with these magnitudes.
目的:众所周知,体育锻炼会影响睡眠,然而,在极端运动条件下的影响研究较少。我们分析了一位连续跑了28次马拉松(每天一次)的运动员的睡眠质量和持续时间。方法采用三种多导睡眠图记录来探讨睡眠依赖性恢复过程:马拉松后、部分恢复和基线。结果参与者报告在挑战期间睡眠质量较低,睡眠时间短,多次醒来,白天嗜睡。我们观察到通过多导睡眠图评估的所有变量在睡眠持续时间、质量和分布上的差异。从基线到体能测试后的最终状态,我们观察到睡眠时间和睡眠效率的逐渐减少。此外,我们观察到睡眠开始和快速眼动睡眠潜伏期增加,慢波睡眠增加45.8%,这影响了体力消耗后的完整睡眠结构。由于高强度和持续的体育锻炼,REM减少了14.4%,而相对于REM, SWS(38.5%)增加了267%。结论:高强度体育锻炼影响睡眠,并受恢复过程调节。本研究的结果强调了SWS在极端体育锻炼引起的身体疲劳恢复中的重要性,这一点可以从SWS的大幅增加中得到证明,SWS几乎占总睡眠时间的40%,甚至超过了第二阶段的百分比。研究还表明,快速眼动睡眠对身体疲劳的恢复没有作用,因为事实上,剧烈的体育锻炼会大大降低快速眼动睡眠的效果。以前的研究没有报道过这样的结果。
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引用次数: 0
A qualitative examination of sanctification: Sources and varieties of appraisals of sacredness 圣化的定性检验:神圣性评价的来源和变化
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100578
Elizabeth J. Krumrei-Mancuso, Janet P. Trammell, Jennifer A. Harriger, Joshua A. Evans
Most mental health professionals are expected to have some basic competency in religious and spiritual issues. Such competency includes knowledge about the role of religion/spirituality in people’s lives, particularly as it relates to mental health. The current research explored people’s cognitive appraisals of sanctification, by which individuals interpret stimuli to be sacred. To gain a better understanding of the spontaneous cognitive appraisals of sanctification people form during daily life, we randomly assigned religious and/or spiritual individuals (N = 144) to an event reconstruction of a time they experienced something as sacred, divine, miraculous, spiritual, holy, or blessed. We qualitatively coded 28 features of these event reconstructions. Participants’ most common descriptions involved sanctification of people, relationships, and places that were not considered sacred in and of themselves, but were considered sacred by association to higher powers or transcendent realities. Common features of sacredness reconstructions included emotions and sensory experiences. We also observed differences in the features associated with each sacred adjective (sacred, divine, miraculous, spiritual, holy, or blessed). We discuss implications for mental health professionals and for the advancement of the science of sanctification.
大多数心理健康专业人员被期望在宗教和精神问题上有一些基本的能力。这种能力包括关于宗教/灵性在人们生活中的作用的知识,特别是与心理健康有关的知识。目前的研究探讨了人们对圣化的认知评价,即个体将刺激解释为神圣的。为了更好地理解人们在日常生活中形成的对圣化的自发认知评价,我们随机分配了宗教和/或精神个体(N = 144),让他们对自己经历的神圣、神圣、奇迹、精神、神圣或祝福的事情进行事件重建。我们对这些事件重构的28个特征进行了定性编码。参与者最常见的描述包括对人、关系和地方的神圣化,这些地方本身并不被认为是神圣的,但由于与更高的力量或超越现实的联系而被认为是神圣的。神圣性重建的共同特征包括情感和感官体验。我们还观察到与每个神圣形容词(神圣的、神圣的、神奇的、精神的、神圣的或有福的)相关的特征的差异。我们讨论对心理健康专业人员的影响和对成圣科学的进步。
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引用次数: 0
Narcolepsy and psychiatric comorbidity: a review of the literature 发作性睡病与精神疾病的共病:文献综述
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100591
Lies Verstraete , Maarten Van Den Bossche

Introduction

Narcolepsy is a chronic sleep-wake disorder characterized by recurrent episodes of excessive daytime sleepiness, hypnagogic hallucinations, and sleep paralysis. There are two subtypes: narcolepsy type 1 (with cataplexy) and narcolepsy type 2 (without cataplexy). This review aims to investigate the comorbidity of psychiatric disorders in narcolepsy.

Methods

We examined this association through a systematic literature review conducted on July 20, 2024. Searches were performed in PubMed and Embase.

Results

In general, the prevalence of comorbid psychiatric disorders in patients with narcolepsy varies considerably. Depression, anxiety disorders and ADHD are considerably more prevalent in patients with narcolepsy than in the general population. The prevalence of comorbid psychotic disorders and a formal diagnosis of an eating disorder seems also higher in narcolepsy, albeit to a lesser extent. Neurodegenerative disorders and addictive problems were not more prevalent than in general population. More evidence is needed on bipolar disorder, obsessive compulsive disorder, autism, intellectual disability and personality disorders.

Conclusion

Overall psychiatric disorders are more prevalent in patients with narcolepsy, but prevalence rates vary widely across disorders. High prevalence of comorbid depression, anxiety disorders and ADHD is reported in narcolepsy. For other psychiatric disorders, current evidence is less conclusive. It is important that clinicians and patients are aware of the comorbidity of narcolepsy and psychiatric disorders.
嗜睡症是一种慢性睡眠-觉醒障碍,以反复发作的日间过度嗜睡、睡眠幻觉和睡眠瘫痪为特征。发作性睡病有两种亚型:1型发作性睡病(伴有发作)和2型发作性睡病(无发作性发作)。本文旨在探讨发作性睡病患者的精神疾病合并症。方法通过于2024年7月20日进行的系统文献综述来检验这种关联。在PubMed和Embase中进行了搜索。结果总体而言,发作性睡病患者共病性精神障碍的患病率差异较大。抑郁症、焦虑症和多动症在发作性睡病患者中比在普通人群中更为普遍。在发作性睡症患者中,共病性精神障碍的患病率和饮食失调的正式诊断似乎也更高,尽管程度较轻。神经退行性疾病和成瘾问题并不比一般人群更普遍。需要更多关于双相情感障碍、强迫症、自闭症、智力残疾和人格障碍的证据。结论总体精神障碍在发作性睡病患者中更为普遍,但不同疾病的患病率差异较大。据报道,发作性睡病患者普遍存在抑郁症、焦虑症和注意力缺陷多动障碍。对于其他精神疾病,目前的证据不那么确凿。重要的是,临床医生和患者意识到发作性睡病和精神疾病的共病性。
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引用次数: 0
Should we worry about how we measure worry? Insights from an updated version of the Italian Penn State Worry Questionnaire 我们应该担心如何衡量忧虑吗?来自更新版的意大利宾夕法尼亚州立大学忧虑问卷的见解
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100579
Gioia Bottesi , Andrea Spoto

Background

Research indicates a rise in self-reported worry, highlighting the need for updated psychometric tools. The Penn State Worry Questionnaire (PSWQ) assesses excessive worry and there is debate over whether only its 11 positively worded items should be used. This study aimed to clarify the factor structure and psychometric properties of the PSWQ and to explore worry features in two diverse Italian community samples from the 2010s and 2020s.

Methods

The 2020s sample included 674 participants (44.5 % female; Mage = 29.44 ± 13.20), while the 2010s sample comprised 411 individuals (61.6 % female; Mage = 36.64 ± 13.73). Methods from Classical Test Theory (CTT) were used to compare alternative PSWQ factor structures, assess the best-fitting model’s reliability and validity, and evaluate measurement invariance (MI) across sexes in the 2020s sample. Item Response Theory (IRT) was applied to refine and confirm the best-fitting factor structure and to compare item and individual locations across samples.

Results

The 11-item one-factor model was the best fit and it showed excellent reliability and concurrent validity. MI across sexes was supported. IRT analyses suggested that items were slightly more difficult for the 2010s sample.

Conclusions

The PSWQ-11 is a valid and reliable tool for assessing worry in the Italian community. The findings suggest that societal issues as well as socio-demographic characteristics may contribute shaping differences in worry features across diverse historical contexts.
研究表明,自我报告的担忧有所增加,这凸显了对更新心理测量工具的需求。宾夕法尼亚州立大学忧虑问卷(PSWQ)评估过度忧虑,对于是否只使用11个积极措辞的项目存在争议。本研究旨在阐明PSWQ的因素结构和心理测量特征,并探讨2010年代和2020年代两个不同意大利社区样本的担忧特征。方法20世纪20年代共纳入674名参与者(女性44.5%;Mage = 29.44±13.20),而2010年代的样本共有411人,其中女性占61.6%;法师= 36.64±13.73)。本研究采用经典检验理论(CTT)的方法比较不同的PSWQ因子结构,评估最佳拟合模型的信度和效度,并评估2020年样本中不同性别的测量不变性(MI)。项目反应理论(IRT)被应用于提炼和确认最适合的因素结构,并在样本中比较项目和个人的位置。结果11项单因素模型拟合效果最佳,具有良好的信度和并发效度。支持跨性别的MI。IRT分析表明,对于2010年的样本来说,项目稍微困难一些。结论PSWQ-11量表是一种有效、可靠的意大利社区焦虑评估工具。研究结果表明,社会问题以及社会人口特征可能会影响不同历史背景下担忧特征的差异。
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引用次数: 0
Daily perceived stress and sexual health in couples with sexual interest/arousal disorder 性兴趣/性唤起障碍夫妇的日常感知压力与性健康
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100582
A. Girouard , S. Bergeron , J.S. Huberman , N.O. Rosen

Objective

Sexual Interest/Arousal Disorder (SIAD) is a common and distressing sexual health concern that may add stress to couple’s daily lives and maintain the low sexual desire/arousal. While stress has been linked to lower sexual desire, sexual satisfaction, and higher sexual distress in cross-sectional studies with community couples, dyadic research at the intersection of stress and sexual health is scarce. We examined the daily associations between perceived stress and sexual health among couples coping with SIAD.

Methods

Women and gender diverse individuals with SIAD, and their partners, (N = 229, Mage = 34.94) completed online validated measures of perceived stress, sexual desire, satisfaction, and distress for 56 days. Data were analyzed with residual dynamic structural equation modeling guided by the Actor-Partner Independence Model.

Results

On days when individuals with SIAD perceived more stress than usual, they and their partners reported lower sexual satisfaction and desire, and higher sexual distress. On days when partners perceived more stress, they and individuals with SIAD reported lower sexual satisfaction and desire, and partners also reported higher sexual distress. Between-person results across the diary period showed similar patterns, though fewer effects overall.

Conclusion

Findings highlight dyadic processes in sexual health whereby one partner’s daily stress was associated with lower sexual health for both partners. Stress might orient partners away from sensitive support provision and interfere with intimacy, which is crucial to sexual health. Interventions fostering sexual health in couples with SIAD should include a focus on stress management.
目的性兴趣/觉醒障碍(SIAD)是一种常见的令人痛苦的性健康问题,它可能给夫妻的日常生活增加压力,并维持较低的性欲/觉醒。虽然在对社区夫妇的横断面研究中,压力与较低的性欲、性满意度和较高的性痛苦有关,但在压力和性健康交叉点的二元研究很少。我们研究了在SIAD夫妇中感知压力和性健康之间的日常联系。方法SIAD女性和不同性别的患者及其伴侣(N = 229,男= 34.94)在56天内完成了感知压力、性欲、满意度和痛苦的在线验证测量。采用基于行动者-伙伴独立模型的剩余动态结构方程模型对数据进行分析。结果当SIAD患者感受到比平时更多的压力时,他们和他们的伴侣报告的性满意度和性欲较低,性痛苦较高。在伴侣感受到更大压力的日子里,他们和SIAD患者报告的性满意度和性欲都较低,伴侣也报告了更高的性痛苦。在日记期间,人与人之间的结果也显示出类似的模式,尽管总体上影响较小。结论:研究结果强调了性健康的二元过程,其中一方的日常压力与双方的性健康较低有关。压力可能会使伴侣远离敏感的支持,并干扰对性健康至关重要的亲密关系。促进SIAD夫妇性健康的干预措施应包括注重压力管理。
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引用次数: 0
Modulating prefrontal cortex activity to alleviate stress-induced working memory deficits: A transcranial direct current (tDCS) study 调节前额叶皮层活动减轻应激性工作记忆缺陷:经颅直流电(tDCS)研究
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100569
Sumit Roy , Yan Fan , Mohsen Mosayebi-Samani , Maren Claus , Fatemeh Yavari , Thomas Kleinsorge , Michael A. Nitsche
This study explores the impact of stress on working memory (WM) performance, and the potential mitigating effects of transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (dlPFC) and ventromedial prefrontal cortex (vmPFC). The study had a mixed, randomized, single-blind, sham-controlled design, with stress induction as within-subject and stimulation condition as between-subject factors. We assessed stress-induced WM deficits using aversive video clips to induce stress and a verbal n-back task to assess WM performance. We analyzed physiological (cortisol and heart rate), behavioral, and electroencephalographic (EEG) changes due to stress before, during, and after WM task performance and their modulation by tDCS. Stress impaired WM performance in the sham stimulation condition for the 3-back load, but not for 2-back or 4-back loads in the WM task and was associated with elevated physiological stress markers. tDCS over the vmPFC led to better WM task performance while stimulation over the dlPFC did not. Active tDCS with both dlPFC and vmPFC stimulation blunted cortisol release in stress conditions compared to sham. The EEG analysis revealed potential mechanisms explaining the behavioral effects of vmPFC stimulation. vmPFC stimulation led to a decreased P200 event-related potential (ERP) component compared to the sham stimulation condition and resulted in higher task-related alpha desynchronization, indicating reduced distractions and better focus during task performance. This study thus shows that the vmPFC might be a potential target for mitigating the effects of stress on WM performance and contributes to the development of targeted interventions for stress-related cognitive impairments.
本研究探讨应激对工作记忆(WM)表现的影响,以及经颅直流电刺激(tDCS)对左背外侧前额叶皮层(dlPFC)和腹内侧前额叶皮层(vmPFC)的潜在缓解作用。该研究采用混合、随机、单盲、假对照设计,应激诱导为受试者内部因素,刺激条件为受试者之间因素。我们使用令人厌恶的视频片段来诱导压力,并使用口头n-back任务来评估WM表现,以此来评估压力诱导的WM缺陷。我们分析了在WM任务执行之前、期间和之后由于应激引起的生理(皮质醇和心率)、行为和脑电图(EEG)变化以及tDCS对它们的调节。在3背负荷的假刺激条件下,应激损害了WM任务的表现,但在2背或4背负荷的WM任务中,应激没有损害WM任务的表现,并且与生理应激标志物升高有关。vmPFC上的tDCS导致更好的WM任务表现,而dlPFC上的刺激则没有。与假手术相比,激活tDCS同时刺激dlPFC和vmPFC使应激条件下的皮质醇释放减弱。脑电图分析揭示了解释vmPFC刺激行为影响的潜在机制。与假刺激相比,vmPFC刺激导致P200事件相关电位(ERP)成分下降,导致更高的任务相关α去同步,表明在任务执行过程中分心减少,注意力更好。因此,本研究表明vmPFC可能是减轻压力对WM表现影响的潜在靶点,并有助于开发针对压力相关认知障碍的针对性干预措施。
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引用次数: 0
Physical performance, health-related quality of life and sleepiness severity of an adult outpatient population with narcolepsy: A cross-sectional analysis 门诊成人发作性睡症患者的身体表现、健康相关生活质量和嗜睡严重程度:一项横断面分析
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2025-04-01 DOI: 10.1016/j.ijchp.2025.100573
R. Tadrous , D. O’ Rourke , N. Murphy , G. Quinn , L. Slattery , J. Broderick

Objectives

This study aimed to profile and explore the correlation between health-related quality of life (HRQoL), sleepiness severity and physical performance in a sample of people with narcolepsy type 1 (NT1).

Methods

This cross-sectional study took place in a dedicated outpatient narcolepsy clinic. The following variables were evaluated: cardiopulmonary fitness, physical activity, muscle strength, muscle endurance, power. HRQoL was assessed using the Short Form-36 (SF-36) and the Functional Outcome of Sleep Questionnaire (FOSQ). Sleepiness Severity was measured by the Epworth Sleepiness Scale (ESS), and symptom severity was assessed using the Narcolepsy Severity Scale (NSS).

Results

A total of 22 participants (31.53 ± 13.17 years, 56.52 % female) completed the test battery. Physical performance was low across all measures. With the exception of accelerometery (54.17 % compliance), there was full compliance (100 %) with the test battery, indicating its feasibility for people with narcolepsy. Results showed that physical performance and HRQoL were markedly reduced compared to normative values in this sample of people with narcolepsy. Self-reported physical activity was associated with higher health-related quality of life (ρ = 0.41; p = 0.05), and greater moderate-vigorous physical activity was associated with higher physical wellbeing (ρ = 0.58; p = 0.04). Higher BMI was associated with significantly lower predicted VO₂ Max (0.001), and wall sit duration (p = 0.039).

Conclusion

The influence of physical performance on sleepiness severity and quality of life warrants further investigation, including the possible physical rehabilitation strategies to target physical performance deficits.
本研究旨在分析和探讨1型发作性睡病(NT1)患者的健康相关生活质量(HRQoL)、嗜睡严重程度和身体表现之间的相关性。方法本横断面研究在一家专门的发作性睡病门诊进行。评估了以下变量:心肺健康、体力活动、肌肉力量、肌肉耐力、力量。HRQoL采用短表36 (SF-36)和睡眠功能结局问卷(FOSQ)进行评估。采用Epworth嗜睡量表(ESS)测量嗜睡严重程度,采用嗜睡严重程度量表(NSS)评估症状严重程度。结果共22名参与者(31.53±13.17岁,女性56.52%)完成了测试。体能表现在所有指标中都很低。除了加速计测试(54.17%)外,测试电池完全符合(100%),表明其适用于嗜睡症患者。结果显示,与正常值相比,嗜睡症患者的身体表现和HRQoL明显降低。自我报告的体力活动与较高的健康相关生活质量相关(ρ = 0.41;P = 0.05),较高的中高强度体力活动与较高的身体健康相关(ρ = 0.58;P = 0.04)。BMI越高,预测vo2max(0.001)和坐壁时间越低(p = 0.039)。结论体能表现对嗜睡严重程度和生活质量的影响值得进一步研究,包括针对体能表现缺陷的可能的体能康复策略。
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引用次数: 0
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International Journal of Clinical and Health Psychology
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