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Efficacy and safety of repetitive Transcranial Magnetic Stimulation and transcranial Direct Current Stimulation in memory deficits in patients with Alzheimer's disease: Meta-analysis and systematic review 重复经颅磁刺激和经颅直流电刺激对阿尔茨海默病患者记忆障碍的疗效和安全性:元分析和系统综述
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-03-01 DOI: 10.1016/j.ijchp.2024.100452
Sara M. Fernandes , Augusto J. Mendes , Pedro F.S. Rodrigues , Ana Conde , Magda Rocha , Jorge Leite

Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are two of the most used non-pharmacological interventions for Alzheimer's Disease (AD). However, most of the clinical trials have focused on evaluating the effects on global cognition and not on specific cognitive functions. Therefore, considering that memory loss is one of the hallmark symptoms of AD, we aim to assess the efficacy and safety of tDCS and rTMS in memory deficits. For that, multilevel random effect models were performed considering the standardized mean difference (SMD) between active and sham stimulation. A total of 19 studies with 411 participants demonstrated positive effects in memory after tDCS (SMD=0.20, p = 0.04) and rTMS (SMD=0.44, p = 0.001). Subgroup analysis revealed that tDCS had greater efficacy when administered in temporal regions (SMD=0.32, p = 0.04), whereas rTMS was superior when applied in frontal regions (SMD=0.61, p < 0.001). Therefore, depending on the brain region of stimulation, both interventions produced a positive effect on memory symptoms in AD patients. Finally, the safety of both techniques was observed in the AD population after the reporting of almost no serious events.

重复经颅磁刺激(rTMS)和经颅直流电刺激(tDCS)是治疗阿尔茨海默病(AD)最常用的两种非药物干预方法。然而,大多数临床试验都侧重于评估对整体认知的影响,而不是对特定认知功能的影响。因此,考虑到记忆力减退是阿尔茨海默病的标志性症状之一,我们旨在评估 tDCS 和经颅磁刺激对记忆力减退的疗效和安全性。为此,我们建立了多层次随机效应模型,考虑了主动刺激和假刺激之间的标准化平均差(SMD)。共有 19 项研究的 411 名参与者证明,tDCS(SMD=0.20,p = 0.04)和经频磁刺激(SMD=0.44,p = 0.001)对记忆力有积极影响。分组分析表明,在颞叶区域施用 tDCS 的疗效更好(SMD=0.32,p = 0.04),而在额叶区域施用 rTMS 的疗效更好(SMD=0.61,p < 0.001)。因此,根据刺激脑区的不同,两种干预方法都能对注意力缺失症患者的记忆症状产生积极影响。最后,这两种技术在AD人群中几乎没有发生严重事件,因此安全性得到了认可。
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引用次数: 0
Effects of victimization and perpetration in observing bullying scenes: an eye-tracker study{es} 观察欺凌场景时受害和施暴的影响:一项眼动追踪研究{es}。
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-02-28 DOI: 10.1016/j.ijchp.2024.100451
Laura Menabò , Simona C.S. Caravita , Grace Skrzypiec , Phillip Slee , Annalisa Guarini

Introduction

Previous research showed that bullying experiences are associated with different ways of interpreting and behaving in bullying dynamics. However, it remains uncertain whether these distinctions can already be present during the first step of information processing: the allocation of attention.

Aims

The study explored attentional patterns of Italian students with different bullying experiences in daily life while observing different roles represented through bullying vignettes.

Methods

Participants (72 students, Mage= 11.18) were categorized as victims, bully-victims, or not involved based on their scores on a self-report questionnaire. They observed 9 bullying vignettes on which different portraits were presented (bully, victim, pro-bully, defender, bystander) while the eye-tracker registered attentional indexes (fixation, visit and duration).

Results

Kruskal- Wallis and pairwise comparisons revealed a significant effect for the portraits of the bully and the pro-bully as bully-victims exhibited greater fixations and visits than victims, while students not involved showed no significant differences with the other groups.

Conclusion

Our research reveals that bully-victims focused more on threatening cues while victims diverged their gaze from them, confirming that the experience of bullying influences how they explore aggressive situations. Learning how involved students direct their attention helps us understand different responses, leading to powerful interventions.

引言 以前的研究表明,欺凌经历与在欺凌动态中的不同解释和行为方式有关。本研究探讨了在日常生活中有不同欺凌经历的意大利学生在观察欺凌小故事中的不同角色时的注意模式。方法根据自我报告问卷的得分,将参与者(72 名学生,平均年龄= 11.18)分为受害者、欺凌-受害者或无关者。结果Kruskal- Wallis 和成对比较显示,欺凌受害者比受害者表现出更多的固定和访问,因此欺凌受害者和支持欺凌者的肖像有显著影响,而未参与欺凌的学生与其他组没有显著差异。结论我们的研究表明,受欺凌者更关注威胁性线索,而受害者则将视线从威胁性线索上移开,这证实了受欺凌的经历会影响他们探索攻击性情境的方式。了解参与其中的学生如何引导他们的注意力有助于我们理解不同的反应,从而采取有力的干预措施。
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引用次数: 0
Reduced stereotypicality and spared use of facial expression predictions for social evaluation in autism 自闭症患者的刻板印象减少,面部表情预测在社交评价中的使用率降低
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-02-23 DOI: 10.1016/j.ijchp.2024.100440
Marta Robles , Irene Ramos-Grille , Amaia Hervás , Enric Duran-Tauleria , Jordi Galiano-Landeira , Jolie B. Wormwood , Christine M. Falter-Wagner , Lorena Chanes

Background/Objective

Autism has been investigated through traditional emotion recognition paradigms, merely investigating accuracy, thereby constraining how potential differences across autistic and control individuals may be observed, identified, and described. Moreover, the use of emotional facial expression information for social functioning in autism is of relevance to provide a deeper understanding of the condition.

Method

Adult autistic individuals (n = 34) and adult control individuals (n = 34) were assessed with a social perception behavioral paradigm exploring facial expression predictions and their impact on social evaluation.

Results

Autistic individuals held less stereotypical predictions than controls. Importantly, despite such differences in predictions, the use of such predictions for social evaluation did not differ significantly between groups, as autistic individuals relied on their predictions to evaluate others to the same extent as controls.

Conclusions

These results help to understand how autistic individuals perceive social stimuli and evaluate others, revealing a deviation from stereotypicality beyond which social evaluation strategies may be intact.

背景/目的通过传统的情绪识别范式对自闭症进行研究,只是调查准确性,从而限制了如何观察、识别和描述自闭症患者与对照组患者之间的潜在差异。此外,在自闭症患者的社会功能中使用情绪面部表情信息对于深入了解自闭症具有重要意义。方法通过社会感知行为范式对成年自闭症患者(34 人)和成年对照组患者(34 人)进行评估,探索面部表情预测及其对社会评价的影响。结果与对照组相比,自闭症患者的刻板预测较少。重要的是,尽管在预测方面存在这种差异,但在使用这种预测进行社会评价方面,不同群体之间并无显著差异,因为自闭症患者在评价他人时与对照组一样依赖于他们的预测。结论这些结果有助于了解自闭症患者是如何感知社会刺激和评价他人的,揭示了在刻板印象之外,社会评价策略可能是完好无损的。
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引用次数: 0
Unraveling the brain mechanisms of source monitoring with non-invasive brain stimulation: A systematic review 通过非侵入性脑部刺激揭示源监测的脑部机制:系统回顾
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-02-17 DOI: 10.1016/j.ijchp.2024.100449
Mélanie Perret , Cécilia Neige , Jerome Brunelin , Marine Mondino

Background/Objective

Source monitoring refers to the ability to determine the source of memories and encompasses three subprocesses: internal source monitoring, reality monitoring, and external source monitoring. Neuroimaging studies provide valuable insights about neural correlates of source monitoring, but the causal relationship between brain and behavior is lacking. This study aimed to identify brain circuits involved in source monitoring by synthesizing the effects of brain stimulation on source monitoring as a function of the targeted brain regions or circuits.

Method

We conducted a systematic review of interventional studies that have examined the effects of brain stimulation on source monitoring across six databases. The principal outcome was the difference of source monitoring performance between active and control stimulation conditions.

Results

23 studies (920 healthy participants and 54 patients with schizophrenia) were included. Our findings revealed the involvement of i) the lateral prefrontal and temporoparietal cortices in internal source monitoring, ii) the medial prefrontal and temporoparietal cortices in reality monitoring, and iii) the precuneus and the left angular gyrus in external source monitoring.

Conclusions

These findings deepen our understanding of the brain mechanisms of source monitoring and highlight specific stimulation targets to alleviate source monitoring deficits.

背景/目的来源监控是指确定记忆来源的能力,包括三个子过程:内部来源监控、现实监控和外部来源监控。神经影像学研究为源监控的神经相关性提供了有价值的见解,但缺乏大脑与行为之间的因果关系。本研究旨在通过综合脑刺激对源监控的影响,确定参与源监控的脑回路,并将其作为目标脑区或脑回路的功能。结果23项研究(920名健康参与者和54名精神分裂症患者)被纳入其中。我们的研究结果表明:i)外侧前额叶和颞顶叶皮层参与了内部信号源监测;ii)内侧前额叶和颞顶叶皮层参与了现实监测;iii)楔前叶和左侧角回参与了外部信号源监测。
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引用次数: 0
Effects of aerobic exercise on cognitive function in adults with major depressive disorder: A systematic review and meta-analysis 有氧运动对重度抑郁症成人认知功能的影响:系统回顾与荟萃分析
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-02-09 DOI: 10.1016/j.ijchp.2024.100447
Fei-Fei Ren , Charles H. Hillman , Wei-Guang Wang , Ruei-Hong Li , Wen-Sheng Zhou , Wen-Ming Liang , Yong Yang , Feng-Tzu Chen , Yu-Kai Chang

Background

Major Depressive Disorder (MDD) is a highly prevalent psychiatric disorder that impairs the cognitive function of individuals. Aerobic exercise stands out as a promising non-pharmacological intervention for enhancing cognitive function and promoting brain health.

While positive impacts of aerobic exercise on executive function in adults with depression have been documented, a comprehensive understanding of its benefits on overall cognitive function, including memory, attention, and processing speed, along with key moderating factors in adults with MDD, remains unexplored. The purpose of the systematic review and meta-analysis was to investigate the effects of aerobic exercise on overall cognitive function in adults with MDD, and to explore whether cognitive sub-domains, aerobic exercise characteristics, and study and sample variables modify the effects of aerobic exercise on cognition.

Methods

Six English electronic databases (Embase, Cochrane Central, Scopus, APA PsycInfo, PubMed, Web of Science) were searched from inception to 2 April 2023. Randomized trials, including adults aged 18 years or above with a diagnosis of clinical depression, of the effects of aerobic exercise on cognitive function in adults with MDD compared to non-aerobic exercise groups were included. A three-level meta-analysis was conducted utilizing a random-effects model in R. The quality of the studies was evaluated using the Physiotherapy Evidence Database (PEDro) scale. The PROSPERO registration number is CRD42022367350.

Results

Twelve randomized trials including 945 adults with MDD were included. Results indicated that aerobic exercise significantly improved overall cognitive function (g = 0.21; 95 % confidence intervals [CI] = 0.07, 0.34), and the sub-domains of memory (g = 0.25; 95 % CI = 0.06, 0.44) and executive function (g = 0.12; 95 % CI = 0.04, 0.20). Significant benefits in cognitive function were found from moderate-to-vigorous (mixed) intensity (g = 0.19; 95 % CI = 0.02, 0.37), aerobic exercise conducted 3 times per week (g = 0.23; 95 % CI = 0.10, 0.38), in sessions < 45 min (g = 0.59; 95 % CI = 0.28, 0.90), and 45–60 min (g = 0.16; 95 % CI = 0.07, 0.26), in aerobic exercise intervention ≤ 12 weeks (g = 0. 26; 95 % CI = 0.08, 0.44).

Limitations

This review only included peer-reviewed English-language studies, which may lead to a language bias. The results of the Egger's test suggested a potential publication bias.

Conclusions

Aerobic exercise is efficacious in improving overall cognitive function and the sub-domains of memory and executive function in adults with major depressive disorder.

背景重度抑郁症(MDD)是一种高发的精神疾病,会损害患者的认知功能。有氧运动是增强认知功能和促进大脑健康的一种很有前景的非药物干预措施。虽然有文献记载了有氧运动对成人抑郁症患者的执行功能有积极影响,但对其对整体认知功能(包括记忆力、注意力和处理速度)的益处以及对成人 MDD 患者的关键调节因素的全面了解仍有待探索。本系统综述和荟萃分析旨在研究有氧运动对患有 MDD 的成人整体认知功能的影响,并探讨认知子领域、有氧运动特征以及研究和样本变量是否会改变有氧运动对认知的影响。纳入的随机试验包括年龄在 18 岁或以上、诊断为临床抑郁症的成人,与非有氧运动组相比,有氧运动对患有 MDD 的成人认知功能的影响。研究质量采用物理治疗证据数据库(PEDro)量表进行评估。PROSPERO注册号为CRD42022367350。结果纳入了12项随机试验,包括945名患有MDD的成人患者。结果表明,有氧运动能明显改善整体认知功能(g = 0.21;95 % 置信区间 [CI] = 0.07,0.34)、记忆子域(g = 0.25;95 % CI = 0.06,0.44)和执行功能(g = 0.12;95 % CI = 0.04,0.20)。每周 3 次(g = 0.23;95 % CI = 0.10,0.38)、每次 45 分钟(g = 0.59;95 % CI = 0.限制本综述只纳入了同行评审的英语研究,这可能会导致语言偏差。结论有氧运动能有效改善重度抑郁障碍成人的整体认知功能以及记忆和执行功能的子领域。
{"title":"Effects of aerobic exercise on cognitive function in adults with major depressive disorder: A systematic review and meta-analysis","authors":"Fei-Fei Ren ,&nbsp;Charles H. Hillman ,&nbsp;Wei-Guang Wang ,&nbsp;Ruei-Hong Li ,&nbsp;Wen-Sheng Zhou ,&nbsp;Wen-Ming Liang ,&nbsp;Yong Yang ,&nbsp;Feng-Tzu Chen ,&nbsp;Yu-Kai Chang","doi":"10.1016/j.ijchp.2024.100447","DOIUrl":"https://doi.org/10.1016/j.ijchp.2024.100447","url":null,"abstract":"<div><h3>Background</h3><p>Major Depressive Disorder (MDD) is a highly prevalent psychiatric disorder that impairs the cognitive function of individuals. Aerobic exercise stands out as a promising non-pharmacological intervention for enhancing cognitive function and promoting brain health.</p><p>While positive impacts of aerobic exercise on executive function in adults with depression have been documented, a comprehensive understanding of its benefits on overall cognitive function, including memory, attention, and processing speed, along with key moderating factors in adults with MDD, remains unexplored. The purpose of the systematic review and meta-analysis was to investigate the effects of aerobic exercise on overall cognitive function in adults with MDD, and to explore whether cognitive sub-domains, aerobic exercise characteristics, and study and sample variables modify the effects of aerobic exercise on cognition.</p></div><div><h3>Methods</h3><p>Six English electronic databases (Embase, Cochrane Central, Scopus, APA PsycInfo, PubMed, Web of Science) were searched from inception to 2 April 2023. Randomized trials, including adults aged 18 years or above with a diagnosis of clinical depression, of the effects of aerobic exercise on cognitive function in adults with MDD compared to non-aerobic exercise groups were included. A three-level meta-analysis was conducted utilizing a random-effects model in R. The quality of the studies was evaluated using the Physiotherapy Evidence Database (PEDro) scale. The PROSPERO registration number is CRD42022367350.</p></div><div><h3>Results</h3><p>Twelve randomized trials including 945 adults with MDD were included. Results indicated that aerobic exercise significantly improved overall cognitive function (<em>g</em> = 0.21; 95 % confidence intervals [CI] = 0.07, 0.34), and the sub-domains of memory (<em>g</em> = 0.25; 95 % CI = 0.06, 0.44) and executive function (<em>g</em> = 0.12; 95 % CI = 0.04, 0.20). Significant benefits in cognitive function were found from moderate-to-vigorous (mixed) intensity (<em>g</em> = 0.19; 95 % CI = 0.02, 0.37), aerobic exercise conducted 3 times per week (<em>g</em> = 0.23; 95 % CI = 0.10, 0.38), in sessions &lt; 45 min (<em>g</em> = 0.59; 95 % CI = 0.28, 0.90), and 45–60 min (<em>g</em> = 0.16; 95 % CI = 0.07, 0.26), in aerobic exercise intervention ≤ 12 weeks (<em>g</em> = 0. 26; 95 % CI = 0.08, 0.44).</p></div><div><h3>Limitations</h3><p>This review only included peer-reviewed English-language studies, which may lead to a language bias. The results of the Egger's test suggested a potential publication bias.</p></div><div><h3>Conclusions</h3><p>Aerobic exercise is efficacious in improving overall cognitive function and the sub-domains of memory and executive function in adults with major depressive disorder.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 2","pages":"Article 100447"},"PeriodicalIF":8.8,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000127/pdfft?md5=7e7d2706ed993f8c66ceaf138a6ae941&pid=1-s2.0-S1697260024000127-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139714568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A randomized controlled trial of therapist-facilitated brief online behavioral parent training for reducing child disruptive behavior 由治疗师主持的简短在线行为父母培训随机对照试验,以减少儿童的破坏性行为
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-02-09 DOI: 10.1016/j.ijchp.2024.100448
Triet Pham , Dave Pasalich , Phu Tran , Richard O'Kearney

Background

Addressing child disruptive behavior in low and middle-income countries (LMICs) is challenging. Therapist-facilitated, multisession, brief, online group parent training offers hope for mitigating this issue. However, trials, particularly in Asia, are limited.

Objective

This study primarily assessed the effectiveness of Brief Behavior Parent Training Vietnam (BBPTV) in reducing child disruptive behavior.

Method

This study was a randomized controlled trial involving 109 Vietnamese parents (mean age = 34.1, 96 % were mothers) of preschool children displaying ongoing disruptive behaviors. Interventions included the BBPTV group (n = 56) receiving a therapist-facilitated, four-session program conducted through online group meetings and the care-as-usual (CAU) group (n = 53) having a 15 min individual online consultation. Primary outcomes, assessed online at two and six months postintervention, encompassed the intensity and frequency of children's disruptive problems. Secondary outcomes involved parenting practices, coercive interactions, marital conflicts, parenting self-efficacy, and parental mental health.

Results

In contrast to CAU, the BBPTV group showed lower child disruptive intensity, reduced parent-child coercive interactions, and diminished marital conflicts, with a higher score in involving parenting two months post-intervention. Six months postintervention, BBPTV also exhibited significantly lower scores in child disruptive intensity and problems, harsh parenting, and coercive processes compared to CAU.

Conclusions

The therapist-facilitated, four-session, internet-delivered group parent intervention resulted in superior and sustained improvements in child disruptive behavior, parenting practices, and parent-child coercive interaction compared to usual care, highlighting the potential for online BBPT to extend mental health care in Vietnam and other LMICs.

背景在中低收入国家(LMICs),解决儿童破坏性行为问题具有挑战性。由治疗师主持的、多课时的、简短的、在线集体家长培训为缓解这一问题带来了希望。本研究主要评估了越南简短行为家长培训(BBPTV)在减少儿童破坏性行为方面的效果。本研究是一项随机对照试验,共有 109 名学龄前儿童的越南家长(平均年龄 = 34.1 岁,96% 为母亲)参与,他们都有持续的破坏性行为。干预措施包括:BBPTV 组(56 人)通过在线小组会议接受由治疗师主持的四节课课程;照常护理 (CAU) 组(53 人)接受 15 分钟的个人在线咨询。在干预后的两个月和六个月进行在线评估的主要结果包括儿童破坏性问题的强度和频率。结果与 CAU 相比,BBPTV 组的儿童破坏性问题强度较低,亲子间的强制性互动减少,婚姻冲突减少,干预后两个月的亲子关系得分较高。与 CAU 相比,干预后六个月,BBPTV 组在儿童破坏性强度和问题、严厉的养育方式和胁迫过程方面的得分也明显降低。结论与常规护理相比,治疗师指导的、四节课的、通过互联网提供的集体家长干预在儿童破坏性行为、养育方式和亲子胁迫互动方面带来了卓越而持续的改善,突出了在线 BBPT 在越南和其他低收入、中等收入国家推广心理健康护理的潜力。
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引用次数: 0
Benchmarks for dialectical behavioural therapy intervention in adults and adolescents with borderline personality symptoms 对有边缘型人格症状的成人和青少年进行辩证行为疗法干预的基准
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-02-06 DOI: 10.1016/j.ijchp.2024.100446
Julieta Azevedo , Diogo Carreiras , Caitlin Hibbs , Raquel Guiomar , Joshua Osborne , Richard Hibbs , Michaela Swales

Background

Dialectical Behaviour Therapy (DBT) is a multi-component cognitive behavioural intervention with proven efficacy in treating people with borderline personality disorder symptoms. Establishing benchmarks for DBT intervention with both adults and adolescents is essential for bridging the gap between research and clinical practice, improving teams' performance and procedures.

Aim

This study aimed to establish benchmarks for DBT using the EQ-5D, Borderline Symptoms List (BSL) and Difficulties in Emotion Regulation Scale (DERS) for adults and adolescents.

Methods

After searching four databases for randomised controlled trials and effectiveness studies that applied standard DBT to people with borderline symptoms, a total of 589 studies were included (after duplicates' removal), of which 16 met our inclusion criteria. A meta-analysis and respective effect-size pooling calculations (Hedges-g) were undertaken, and heterogeneity between studies was assessed with I2 and Q tests. Benchmarks were calculated using pre–post treatment means of the studies through aggregation of adjusted effect sizes and critical values.

Results

DBT aggregated effect sizes per subsample derived from RCTs and effectiveness studies are presented, along with critical values, categorised by age group (adults vs adolescents), mode of DBT treatment (full-programme vs skills-training) and per outcome measure (EQ-5D, BSL and DERS).

Conclusions

Practitioners from routine clinical practice delivering DBT and researchers can now use these benchmarks to evaluate their teams' performance according to their clients' outcomes, using the EQ-5D, BSL and DERS. Through benchmarking, teams can reflect on their teams' efficiency and determine if their delivery needs adjustment or if it is up to the standards of current empirical studies.

背景辩证行为疗法(DBT)是一种多成分认知行为干预方法,在治疗边缘型人格障碍症状患者方面疗效显著。本研究旨在使用 EQ-5D、边缘型症状列表 (Borderline Symptoms List, BSL) 和情绪调节困难量表 (Difficulties in Emotion Regulation Scale, DERS) 为成人和青少年的 DBT 干预建立基准。方法在检索了四个数据库中对边缘症患者采用标准 DBT 的随机对照试验和有效性研究后,共纳入了 589 项研究(去除重复研究后),其中 16 项符合我们的纳入标准。我们进行了荟萃分析和相应的效应大小汇集计算(Hedges-g),并通过 I2 和 Q 检验评估了研究之间的异质性。结果按照年龄组(成人 vs 青少年)、DBT 治疗模式(全方案 vs 技能培训)和结果测量(EQ-5D、BSL 和 DERS)分类,列出了从 RCT 和有效性研究中得出的每个子样本的 DBT 合计效应大小以及临界值。结论提供 DBT 的常规临床实践人员和研究人员现在可以使用这些基准,根据客户的结果,使用 EQ-5D、BSL 和 DERS 评估其团队的表现。通过基准评估,团队可以反思其团队的效率,并确定其实施是否需要调整,或者是否达到了当前实证研究的标准。
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引用次数: 0
Distress tolerance as a mediator of mindfulness-based intervention for anxiety and depression: Evidence from two randomized controlled trials 压力耐受性是以正念为基础的焦虑和抑郁干预的中介:来自两项随机对照试验的证据
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-02-01 DOI: 10.1016/j.ijchp.2024.100445
Yanjuan Li , Mengyao He , Zhenzhen Wang , Stefan G. Hofmann , Xinghua Liu

Objective

We aimed to investigate whether distress tolerance mediated the effects of mindfulness-based intervention (MBI) on anxiety and depression with two randomized controlled studies.

Method

In Study 1, 374 participants with at least moderate emotional distress were randomized to an intervention group (N = 174) and a waitlist control group (N = 173). Mindfulness, distress tolerance, anxiety, and depression were measured at the pre-test, week 3, week 5, and post-test. In Study 2, 170 participants with emotional disorders were randomized to an intervention group (N = 86) and a control group (N = 84). The same variables were assessed at pre-test, weekly during the intervention, and post-test.

Results

In both studies, linear mixed effect models showed that compared to the control group, mindfulness, distress tolerance, anxiety, and depression significantly improved in the intervention group. Parallel process latent growth curve models showed that changes in distress tolerance mediated the effects of the MBI on changes in anxiety and depression. Random-intercept cross-lagged panel models found that distress tolerance temporally preceded depression, but not anxiety.

Conclusions

Distress tolerance is a potential mechanism underlying MBIs. Interventions targeting distress tolerance could be embedded in MBIs to enhance the intervention effects for emotional distress.

方法在研究 1 中,374 名至少有中度情绪困扰的参与者被随机分配到干预组(174 人)和候补对照组(173 人)。分别在测试前、测试第 3 周、测试第 5 周和测试后对正念、痛苦容忍度、焦虑和抑郁进行了测量。在研究 2 中,170 名患有情绪障碍的参与者被随机分为干预组(86 人)和对照组(84 人)。结果在这两项研究中,线性混合效应模型显示,与对照组相比,干预组的正念、苦恼容忍度、焦虑和抑郁都有显著改善。平行过程潜增长曲线模型显示,困扰容忍度的变化介导了 MBI 对焦虑和抑郁变化的影响。随机截距交叉滞后面板模型发现,困扰容忍度在时间上先于抑郁,而不是先于焦虑。压力耐受性是 MBI 的潜在机制,以压力耐受性为目标的干预措施可以嵌入 MBI 中,以增强对情绪困扰的干预效果。
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引用次数: 0
Interventions for psychiatric disorders among university students: An umbrella review of systematic reviews and meta-analyses 对大学生精神障碍的干预:系统综述和荟萃分析总览
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-01-01 DOI: 10.1016/j.ijchp.2023.100431
Huan Huang , Shaofen Huang , Shiyun Chen , Xuping Gao , Jun Cai , Yonghui Feng , Jiazi Liu , Xin Su , Jiamin Qiu , Shiwen Zhang , Ying Xu , Zheng Liu , Ting Wang , Fangfang Zeng

Background

Mental disorders are considered to be the main reason for the increase of the disease burden. College students seem to be more vulnerable to the adverse effects of stress, which makes them more at risk of suffering from mental disorders. This umbrella review aimed to evaluate the credibility of published evidence regarding the effects of interventions on mental disorders among university students.

Methods

To identify systematic reviews and meta-analyses investigating the effects of interventions on mental disorders in the university student population, extensive searches were carried out in databases including PubMed, Embase, and the Cochrane Database, spanning from inception to July 21, 2023. Subsequently, a thorough reanalysis of crucial parameters such as summary effect estimates, 95 % confidence intervals, heterogeneity I2 statistic, 95 % prediction intervals, small-study effects, and excess significance bias was performed for each meta-analysis found.

Results

Nineteen articles involving 74 meta-analyses were included. Our grading of the current evidence showed that interventions based on exercise, Cognitive-behavioural Intervention (CBI), mindfulness-based interventions (MBI), and other interventions like mood and anxiety interventions (MAI) were effective whereas exercise intervention had the highest effect size for both depression and anxiety among university students. However, the credibility of the evidence was weak for most studies. Besides, suggestive evidence was observed for the positive effects of CBI on sleep disturbance(SMD: -0.603, 95 % CI: -0.916, -0.290; P-random effects<0.01) and MAI on anxiety (Hedges'g = -0.198, 95 % CI: -0.302, -0.094; P-random effects<0.01).

Conclusion

Based on our findings, it appears that exercise interventions, CBI, and MAI have the potential to alleviate symptoms related to mental disorders. Despite the overall weak credibility of the evidence and the strength of the associations, these interventions offer a promising avenue for further exploration and research in the future. More high-quality randomized controlled trials should be taken into account to verify the effects of these interventions on various mental disorders.

背景精神障碍被认为是疾病负担加重的主要原因。大学生似乎更容易受到压力的不良影响,这使他们更有可能患上精神障碍。本综述旨在评估已发表的有关干预措施对大学生精神障碍影响的证据的可信度。方法为了确定调查干预措施对大学生精神障碍影响的系统综述和荟萃分析,我们在包括PubMed、Embase和Cochrane数据库在内的数据库中进行了广泛的检索,时间跨度从开始到2023年7月21日。随后,对所发现的每项荟萃分析的关键参数,如摘要效应估计值、95 % 置信区间、异质性 I2 统计量、95 % 预测区间、小研究效应和过度显著性偏倚进行了全面的重新分析。我们对现有证据进行了分级,结果显示,基于运动的干预、认知行为干预(CBI)、正念干预(MBI)以及其他干预,如情绪和焦虑干预(MAI)都是有效的,而运动干预对大学生抑郁和焦虑的效果最大。然而,大多数研究的证据可信度较低。此外,还观察到提示性证据表明,情绪和焦虑干预对睡眠障碍(SMD:-0.603,95 % CI:-0.916,-0.290;P-随机效应<0.01)和情绪和焦虑干预对焦虑(Hedges'g = -0.198,95 % CI:-0.302,-0.094;P-随机效应<0.01)有积极影响。尽管证据的可信度和关联的强度总体上较弱,但这些干预措施为未来的进一步探索和研究提供了一个前景广阔的途径。应考虑进行更多高质量的随机对照试验,以验证这些干预措施对各种精神障碍的影响。
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引用次数: 0
Fear, anxiety and depression in gastrointestinal stromal tumor (GIST) patients in the Netherlands: Data from a cross-sectional multicenter study 荷兰胃肠道间质瘤 (GIST) 患者的恐惧、焦虑和抑郁:一项横断面多中心研究的数据
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-01-01 DOI: 10.1016/j.ijchp.2023.100434
Deborah van de Wal , Dide den Hollander , Ingrid M.E. Desar , Hans Gelderblom , Astrid W. Oosten , Anna K.L. Reyners , Neeltje Steeghs , Olga Husson , Winette T.A. van der Graaf

Background

This study aims to (1) investigate the prevalence of anxiety, depression and severe fear of cancer recurrence or progression in gastrointestinal stromal tumor (GIST) patients treated in a curative or palliative setting, (2) compare their prevalence with a norm population, (3) identify factors associated with anxiety, depression and severe fear, and (4) study the impact of these psychological symptoms on health-related quality of life (HRQoL).

Methods

In a cross-sectional study, GIST patients completed the Hospital Anxiety and Depression Scale, Cancer Worry Scale, and EORTC QLQ-C30.

Results

Of the 328 patients, 15% reported anxiety, 13% depression, and 43% had severe fear. Anxiety and depression levels were comparable between the norm population and patients in the curative setting, but significantly higher for patients in the palliative setting. Having other psychological symptoms was associated with anxiety, while current TKI treatment and anxiety were associated with depression. Severe fear was associated with age, female sex, palliative treatment setting, anxiety, and GIST-related concerns.

Conclusion

GIST patients treated in a palliative setting are more prone to experience psychological symptoms, which can significantly impair their HRQoL. These symptoms deserve more attention in clinical practice, in which regular screening can be helpful, and appropriate interventions should be offered.

背景本研究旨在(1)调查接受治愈性或姑息性治疗的胃肠道间质瘤(GIST)患者中焦虑、抑郁和对癌症复发或进展的严重恐惧的发生率;(2)将其发生率与正常人群进行比较;(3)确定与焦虑、抑郁和严重恐惧相关的因素;以及(4)研究这些心理症状对健康相关生活质量(HRQoL)的影响。方法 在一项横断面研究中,GIST 患者填写了医院焦虑抑郁量表、癌症担忧量表和 EORTC QLQ-C30。焦虑和抑郁水平与正常人群和接受治疗的患者相当,但接受姑息治疗的患者焦虑和抑郁水平明显更高。有其他心理症状与焦虑有关,而当前的TKI治疗和焦虑与抑郁有关。严重恐惧与年龄、女性性别、姑息治疗环境、焦虑和 GIST 相关问题有关。这些症状值得在临床实践中给予更多关注,其中定期筛查可能会有所帮助,并应提供适当的干预措施。
{"title":"Fear, anxiety and depression in gastrointestinal stromal tumor (GIST) patients in the Netherlands: Data from a cross-sectional multicenter study","authors":"Deborah van de Wal ,&nbsp;Dide den Hollander ,&nbsp;Ingrid M.E. Desar ,&nbsp;Hans Gelderblom ,&nbsp;Astrid W. Oosten ,&nbsp;Anna K.L. Reyners ,&nbsp;Neeltje Steeghs ,&nbsp;Olga Husson ,&nbsp;Winette T.A. van der Graaf","doi":"10.1016/j.ijchp.2023.100434","DOIUrl":"https://doi.org/10.1016/j.ijchp.2023.100434","url":null,"abstract":"<div><h3>Background</h3><p>This study aims to (1) investigate the prevalence of anxiety, depression and severe fear of cancer recurrence or progression in gastrointestinal stromal tumor (GIST) patients treated in a curative or palliative setting, (2) compare their prevalence with a norm population, (3) identify factors associated with anxiety, depression and severe fear, and (4) study the impact of these psychological symptoms on health-related quality of life (HRQoL).</p></div><div><h3>Methods</h3><p>In a cross-sectional study, GIST patients completed the Hospital Anxiety and Depression Scale, Cancer Worry Scale, and EORTC QLQ-C30.</p></div><div><h3>Results</h3><p>Of the 328 patients, 15% reported anxiety, 13% depression, and 43% had severe fear. Anxiety and depression levels were comparable between the norm population and patients in the curative setting, but significantly higher for patients in the palliative setting. Having other psychological symptoms was associated with anxiety, while current TKI treatment and anxiety were associated with depression. Severe fear was associated with age, female sex, palliative treatment setting, anxiety, and GIST-related concerns.</p></div><div><h3>Conclusion</h3><p>GIST patients treated in a palliative setting are more prone to experience psychological symptoms, which can significantly impair their HRQoL. These symptoms deserve more attention in clinical practice, in which regular screening can be helpful, and appropriate interventions should be offered.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100434"},"PeriodicalIF":8.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260023000704/pdfft?md5=afed5d4462dd59399b8cb7befcdc3f83&pid=1-s2.0-S1697260023000704-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Journal of Clinical and Health Psychology
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