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The experimental study of consciousness: Is psychology travelling back to the future? 意识的实验研究:心理学正在回到未来吗?
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-06-21 DOI: 10.1016/j.ijchp.2024.100475
Óscar F. Gonçalves , Joana Sayal, Fábio Lisboa, Pedro Palhares

It was with the promise of rendering an experimental approach to consciousness that psychology started its trajectory as an independent science more than 150 years ago. Here, we will posit that the neurosciences were instrumental in leading psychology to resume the study of consciousness by projecting an empirical agenda for the future. First, we will start by showing how scientists were able to venture into the consciousness of supposedly unconscious patients, opening the door for the identification of important neural correlates of distinct consciousness states. Then, we will describe how different technological advances and elegant experimental paradigms helped in establishing important neuronal correlates of global consciousness (i.e., being conscious at all), perceptual consciousness (i.e., being conscious of something), and self-consciousness (i.e., being conscious of itself). Finally, we will illustrate how the study of complex consciousness experiences may contribute to the clarification of the mechanisms associated with global consciousness, the relationship between perceptual and self-consciousness, and the interface among distinct self-consciousness domains. In closing, we will elaborate on the road ahead of us for re-establishing psychology as a science of consciousness.

150 多年前,心理学作为一门独立的科学开始了它的发展轨迹,并承诺将以实验方法来研究意识。在这里,我们将假设,神经科学在引领心理学恢复对意识的研究方面发挥了重要作用,为未来预测了一个实证议程。首先,我们将展示科学家是如何冒险进入本应无意识的病人的意识中,为确定不同意识状态的重要神经相关性打开大门的。然后,我们将介绍不同的技术进步和优雅的实验范式是如何帮助确定全局意识(即完全有意识)、知觉意识(即对某些事物有意识)和自我意识(即对自身有意识)的重要神经元相关性的。最后,我们将说明对复杂意识体验的研究如何有助于澄清与全局意识相关的机制、知觉意识与自我意识之间的关系以及不同自我意识领域之间的联系。最后,我们将详细阐述重建心理学作为意识科学的道路。
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引用次数: 0
Phenomenological memory characteristics and impact of near-death experience in critically ill survivors: Observations at discharge and after a 1-year follow-up 危重病幸存者濒死体验的现象记忆特征及其影响:出院时和一年随访后的观察结果
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-06-18 DOI: 10.1016/j.ijchp.2024.100478
Charlotte Martial , Pauline Fritz , Helena Cassol , Olivia Gosseries , Bernard Lambermont , Benoit Misset , Anne-Françoise Rousseau

Background

It is not rare that intensive care unit (ICU) patients report unusual subjective experiences, ranging from a feeling of harmony with the environment to complex phenomena such as near-death experience (NDE). This 1-year follow-up study investigates the characteristics and potential global impact of the NDE memories recalled by ICU survivors.

Method

We prospectively enrolled 126 adult survivors of a prolonged (>7days) ICU stay (all etiologies), including 19 (15 %) who reported a NDE as identified by the Greyson NDE scale. The NDE group underwent a semi-structured interview one month later evaluating their memory characteristics and the associated life-threatening situation. One year after inclusion, all patients (regardless of whether they recalled an NDE) were contacted for a follow-up Greyson NDE scale assessment and questions about their ICU experience and opinions on death since discharge.

Results

The Greyson NDE scale revealed that the most frequently reported features were altered time perception, heightened senses and life review, and the Greyson total scores did not evolve over time. NDE memories persisted, with a consequent number of phenomenological characteristics (e.g., visual details, emotions). One year post-ICU, two patients (18 %) of the NDE group and 12 (24 %) of the non-NDE group were less afraid of death.

Conclusions

Results emphasize the clinical importance of interviewing all ICU patients to explore any memory after an ICU stay.

背景重症监护室(ICU)患者报告不寻常的主观体验并不罕见,从与环境和谐相处的感觉到濒死体验(NDE)等复杂现象,不一而足。这项为期 1 年的随访研究调查了 ICU 幸存者回忆的 NDE 记忆的特征和潜在的全球影响。方法我们前瞻性地招募了 126 名长期(7 天)ICU(所有病因)住院的成年幸存者,其中 19 人(15%)报告了经格雷森 NDE 量表鉴定的 NDE。NDE 组患者在一个月后接受了半结构化访谈,评估了他们的记忆特征和相关的危及生命的情况。结果格雷森NDE量表显示,最常报告的特征是时间感知改变、感觉增强和生命回顾,格雷森总分并没有随着时间的推移而变化。NDE 记忆持续存在,并随之产生了一些现象学特征(如视觉细节、情感)。重症监护室一年后,濒死记忆组中的两名患者(18%)和非濒死记忆组中的 12 名患者(24%)对死亡的恐惧有所减轻。
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引用次数: 0
A quantitative study on peripersonal space in anorexia nervosa and healthy subjects: Role of social variables and association with psychopathology 关于神经性厌食症患者和健康受试者周身空间的定量研究:社会变量的作用以及与精神病理学的关联
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-06-18 DOI: 10.1016/j.ijchp.2024.100476
Paola Longo , Eugenio Scaliti , Matteo Panero , Federica Toppino , Annalisa Brustolin , Benedetta Salis , Maria Carla Lacidogna , Giovanni Abbate-Daga , Matteo Martini

Objectives

This study investigates peripersonal space (PPS) modulation in patients with anorexia nervosa (AN) versus healthy controls (HCs) and explores associations between PPS, eating-related, and general psychopathology.

Method

Forty-six patients and 42 HCs completed a computer-based task observing videos of an approaching actor (male or female) displaying different facial expressions along with a non-social condition. Then, participants completed self-report questionnaires assessing eating-related and general psychopathology.

Results

Mixed-models revealed that both groups adjusted PPS based on task conditions, with a gender effect favoring closer proximity to female actor. HCs reduced PPS amplitude progressively during the task, while patients did not show this effect. In patients, wider PPS correlated with lower self-esteem and facial expression identification accuracy, while in HCs, PPS was associated to body dissatisfaction and anxiety symptoms.

Conclusion

These findings enhance understanding of bodily self-consciousness, suggesting PPS consideration in therapeutic interactions with patients with AN and as a potential target in treatments addressing social impairment.

方法46名神经性厌食症患者和42名健康对照者完成了一项基于计算机的任务,在非社交条件下观察一名靠近的演员(男性或女性)展示不同面部表情的视频。结果混合模型显示,两组患者都根据任务条件调整了PPS,性别效应更倾向于靠近女性演员。高危人群在任务过程中会逐渐减小 PPS 振幅,而患者则不会出现这种效应。在患者中,较宽的 PPS 与较低的自尊和面部表情识别准确性相关,而在 HCs 中,PPS 与身体不满意和焦虑症状相关。结论:这些发现加深了人们对身体自我意识的理解,建议在与 AN 患者的治疗互动中考虑 PPS,并将其作为解决社交障碍的潜在治疗目标。
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引用次数: 0
Psychological characteristics associated with chemsex among men who have sex with men: Internalized homophobia, conscientiousness and serostatus as predictive factors 与男男性行为者的化学性行为有关的心理特征:作为预测因素的内化恐同症、自觉性和血清状况
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 DOI: 10.1016/j.ijchp.2024.100465
Benjamín Rodríguez-Expósito , Jennifer A. Rieker , Sara Uceda , Ana Isabel Beltrán-Velasco , Víctor Echeverry-Alzate , Manuel Gómez-Ortega , Apoyo Positivo , Manuel Reiriz

Background

Although significant progress has been made in the rights of the LGBTQ+ community, even today this population still faces stigma and discrimination that impacts their mental health. In the case of men who have sex with men, it has been demonstrated that the use of drugs in a sexual context (chemsex) is one of the coping mechanisms and means of escape to deal with these situations.

Method

We assessed 284 native Spanish speakers’ participants, 45,4 % were not engaged in sexualised drug use (n = 129) while 54,6 % were chemsex users (n = 155) using 18,7 % of them the injected via. The participants completed six questionnaires about life and sexual satisfaction, depression, anxiety, internalised homophobia and personality. Bivariate and multivariable logistic regression were performed to assess the associations between sexual behaviour-related and psychological variables. Kruskal-Wallis H test was used to analysed the impact on mental health of the administration via.

Results

Aged, unprotected sexual relationships, positive serostatus, homonegativity and conscientiousness predicted the chemsex engagement. Furthermore, we found differences regarding the administration via.

Conclusions

We conclude that mental health significantly correlates with the practice of chemsex, highlighting the importance of integrating mental health considerations into the prevention of risky sexual behaviors.

背景尽管在 LGBTQ+ 群体的权利方面已经取得了重大进展,但时至今日,这一群体仍然面临着影响其心理健康的羞辱和歧视。方法我们对 284 名以西班牙语为母语的参与者进行了评估,其中 45.4% 的人没有使用过毒品(129 人),54.6% 的人使用过毒品(155 人),其中 18.7% 的人通过注射使用过毒品。参与者填写了六份问卷,内容涉及生活和性满意度、抑郁、焦虑、内化的同性恋恐惧症和人格。为了评估性行为相关变量与心理变量之间的联系,研究人员进行了二元和多元逻辑回归。结果年龄、无保护性关系、阳性血清状态、同性恋倾向和自觉性预测了化学性行为的参与度。此外,我们还发现了管理方式的差异。结论我们得出结论,心理健康与性爱行为有显著相关性,这凸显了将心理健康因素纳入危险性行为预防的重要性。
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引用次数: 0
MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume MIR137 导致精神分裂症的多基因风险和ephrin 调节通路:在侧脑室和胼胝体体积中的作用
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 DOI: 10.1016/j.ijchp.2024.100458
G.A.M. Blokland , N. Maleki , J. Jovicich , R.I. Mesholam-Gately , L.E. DeLisi , J.A. Turner , M.E. Shenton , A.N. Voineskos , R.S. Kahn , J.L. Roffman , D.J. Holt , S. Ehrlich , Z. Kikinis , P. Dazzan , R.M. Murray , J. Lee , K. Sim , M. Lam , S.M.C. de Zwarte , E. Walton , E.C. del Re

Background/Objective. Enlarged lateral ventricle (LV) volume and decreased volume in the corpus callosum (CC) are hallmarks of schizophrenia (SZ). We previously showed an inverse correlation between LV and CC volumes in SZ, with global functioning decreasing with increased LV volume. This study investigates the relationship between LV volume, CC abnormalities, and the microRNA MIR137 and its regulated genes in SZ, because of MIR137’s essential role in neurodevelopment. Methods. Participants were 1224 SZ probands and 1466 unaffected controls from the GENUS Consortium. Brain MRI scans, genotype, and clinical data were harmonized across cohorts and employed in the analyses. Results. Increased LV volumes and decreased CC central, mid-anterior, and mid-posterior volumes were observed in SZ probands. The MIR137-regulated ephrin pathway was significantly associated with CC:LV ratio, explaining a significant proportion (3.42 %) of CC:LV variance, and more than for LV and CC separately. Other pathways explained variance in either CC or LV, but not both. CC:LV ratio was also positively correlated with Global Assessment of Functioning, supporting previous subsample findings. SNP-based heritability estimates were higher for CC central:LV ratio (0.79) compared to CC or LV separately. Discussion. Our results indicate that the CC:LV ratio is highly heritable, influenced in part by variation in the MIR137-regulated ephrin pathway. Findings suggest that the CC:LV ratio may be a risk indicator in SZ that correlates with global functioning.

背景/目的。侧脑室(LV)容积增大和胼胝体(CC)容积减小是精神分裂症(SZ)的特征。我们以前的研究表明,精神分裂症患者的侧脑室容量与胼胝体容量之间存在反相关性,随着侧脑室容量的增加,患者的整体功能会下降。由于 MIR137 在神经发育过程中起着至关重要的作用,本研究将探讨 SZ 中 LV 容量、CC 异常、microRNA MIR137 及其调控基因之间的关系。研究方法研究对象是来自 GENUS 协会的 1224 名 SZ 疑似患者和 1466 名未受影响的对照者。脑磁共振成像扫描、基因型和临床数据在各队列中统一,并用于分析。结果显示在SZ疑似患者中观察到左心室容积增大,CC中央、前中部和后中部容积减小。MIR137调控的ephrin通路与CC:LV比值显著相关,可解释CC:LV变异的很大一部分(3.42%),比单独解释LV和CC的变异要多。其他途径可以解释 CC 或 LV 的变异,但不能同时解释 CC 和 LV 的变异。CC:LV比值还与全球功能评估呈正相关,这支持了之前的子样本研究结果。基于 SNP 的遗传率估计值,CC 中心:左心室比率(0.79)高于 CC 或左心室分别的遗传率估计值。讨论我们的研究结果表明,CC:LV比率具有高度遗传性,部分原因是受MIR137调控的ephrin通路变异的影响。研究结果表明,CC:LV比率可能是SZ的一个风险指标,与整体功能相关。
{"title":"MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume","authors":"G.A.M. Blokland ,&nbsp;N. Maleki ,&nbsp;J. Jovicich ,&nbsp;R.I. Mesholam-Gately ,&nbsp;L.E. DeLisi ,&nbsp;J.A. Turner ,&nbsp;M.E. Shenton ,&nbsp;A.N. Voineskos ,&nbsp;R.S. Kahn ,&nbsp;J.L. Roffman ,&nbsp;D.J. Holt ,&nbsp;S. Ehrlich ,&nbsp;Z. Kikinis ,&nbsp;P. Dazzan ,&nbsp;R.M. Murray ,&nbsp;J. Lee ,&nbsp;K. Sim ,&nbsp;M. Lam ,&nbsp;S.M.C. de Zwarte ,&nbsp;E. Walton ,&nbsp;E.C. del Re","doi":"10.1016/j.ijchp.2024.100458","DOIUrl":"https://doi.org/10.1016/j.ijchp.2024.100458","url":null,"abstract":"<div><p><em>Background/Objective.</em> Enlarged lateral ventricle (LV) volume and decreased volume in the corpus callosum (CC) are hallmarks of schizophrenia (SZ). We previously showed an inverse correlation between LV and CC volumes in SZ, with global functioning decreasing with increased LV volume. This study investigates the relationship between LV volume, CC abnormalities, and the microRNA MIR137 and its regulated genes in SZ, because of MIR137’s essential role in neurodevelopment. <em>Methods</em>. Participants were 1224 SZ probands and 1466 unaffected controls from the GENUS Consortium. Brain MRI scans, genotype, and clinical data were harmonized across cohorts and employed in the analyses. <em>Results.</em> Increased LV volumes and decreased CC central, mid-anterior, and mid-posterior volumes were observed in SZ probands. The MIR137-regulated ephrin pathway was significantly associated with CC:LV ratio, explaining a significant proportion (3.42 %) of CC:LV variance, and more than for LV and CC separately. Other pathways explained variance in either CC or LV, but not both. CC:LV ratio was also positively correlated with Global Assessment of Functioning, supporting previous subsample findings. SNP-based heritability estimates were higher for CC central:LV ratio (0.79) compared to CC or LV separately. <em>Discussion.</em> Our results indicate that the CC:LV ratio is highly heritable, influenced in part by variation in the MIR137-regulated ephrin pathway. Findings suggest that the CC:LV ratio may be a risk indicator in SZ that correlates with global functioning.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 2","pages":"Article 100458"},"PeriodicalIF":8.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000231/pdfft?md5=b52de252ec1cfaf7528915eebfab4f7a&pid=1-s2.0-S1697260024000231-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140539827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mindfulness-based intervention reduce interference of negative stimuli to working memory in individuals with subclinical depression: A randomized controlled fMRI study 正念干预可减少亚临床抑郁症患者工作记忆中负面刺激的干扰:随机对照 fMRI 研究
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 DOI: 10.1016/j.ijchp.2024.100459
Chengjin Hong , Cody Ding , Yiwen Chen , Shiyue Cao , Yi Hou , Weiyu Hu , Dong Yang

Background

Individuals with subclinical depression are prone to major depression and experience emotional responses and attentional biases to negative stimuli.

Method

In a randomized controlled study (N = 42) using functional magnetic resonance imaging (fMRI), we examined the neurocognitive mechanisms behind mindfulness-based cognitive therapy (MBCT) combining loving-kindness meditation (LKM) on a group with subclinical depression compared with the relaxation group across emotional face n-back (EFNBACK) tasks and resting state. We also collected behavioral and self-reported data to confirm neurocognitive results.

Results

During EFNBACK, the MBCT+LKM group showed greater activation in the left lingual gyrus and right inferior lateral occipital cortex. During rest, the MBCT+LKM group demonstrated increased connectivity of the anterior cingulate cortex and right inferior lateral occipital cortex, right anterior insula and left precentral gyrus. From amplitude of low frequency fluctuation (ALFF) data, activity in brain regions associated with cognitive control decreased and activity in brain regions associated with sensorimotor increased.

Conclusion

These results suggest that MBCT+LKM alleviate depression for subclinical individuals through improving executive function when they face negative stimuli.

方法在一项使用功能磁共振成像(fMRI)的随机对照研究(N = 42)中,我们研究了基于正念的认知疗法(MBCT)结合慈爱冥想(LKM)背后的神经认知机制,与放松组相比,亚临床抑郁症患者在情绪面孔回溯(EFNBACK)任务和静息状态下的神经认知机制。我们还收集了行为和自我报告数据,以确认神经认知结果。结果在 EFNBACK 过程中,MBCT+LKM 组显示左侧舌回和右侧下外侧枕叶皮层的激活程度更高。在休息时,MBCT+LKM 组显示前扣带回皮层和右枕下外侧皮层、右侧岛叶前部和左侧中央前回的连接性增强。从低频波动幅度(ALFF)数据来看,与认知控制相关的脑区活动减少,而与感觉运动相关的脑区活动增加。
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引用次数: 0
High-intensity interval training (HIIT) and slow breathing interventions alleviate premature ejaculation (PE) symptoms 高强度间歇训练(HIIT)和慢速呼吸干预可减轻早泄(PE)症状
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 DOI: 10.1016/j.ijchp.2024.100457
Caoyuan Niu , Guangju Wen , Daniel Ventus , Patrick Jern , Thomas J. Nyman , Yansong Li , Pekka Santtila

Background

Physical exercise may alleviate premature ejaculation symptoms, a prevalent male sexual dysfunction linked to a series of negative outcomes for men and their partners.

Objective

We investigated the effectiveness of high-intensity interval training (HIIT) and slow breathing interventions on premature ejaculation symptoms and their relation to autonomic activity and attention regulation.

Method

Chinese adult men (N = 76, M = 21.89, SD = 3.32) with premature ejaculation completed one of the two-week interventions in their homes or as participants in a normal breathing control group; they reported their age, height, weight, physical activity level, premature ejaculation symptoms, and attention regulation. In the HIIT group, 26 participants engaged in a 7-minute HIIT each day. In the slow breathing group, 25 participants performed 7-minute slow breathing exercises per day while the 25 participants in the normal breathing group similarly performed normal breathing exercises. All participants measured their heart rate once before and five times (with one-minute intervals) after the intervention. When participants had penile-vaginal sex with their partners, they measured their heart rate once after ejaculation.

Results

Time × Intervention interaction was significant with lower levels of premature ejaculation symptoms on Days 12, 13, and 14 in the HIIT group (M ± SD = 16.19 ± 3.45, 15.96 ± 3.43, and 15.15 ± 3.62) compared to the normal breathing group (M ± SD = 17.68 ± 3.06, 17.68 ± 3.15, and 17.44 ± 3.25). Higher levels of attention regulation were associated with fewer premature ejaculation symptoms. We also found that a larger increase in heart rate from resting to after sex was associated with fewer premature ejaculation symptoms.

Conclusion

Compared to the control group, the efficacy of two weeks of HIIT exercise in mitigating PE symptoms suggests its potential as a novel treatment for PE.

背景体育锻炼可减轻早泄症状,早泄是一种普遍存在的男性性功能障碍,对男性及其伴侣造成一系列负面影响。目的我们研究了高强度间歇训练(HIIT)和慢速呼吸干预对早泄症状的影响及其与自律神经活动和注意力调节的关系。方法患有早泄的中国成年男性(N = 76,M = 21.89,SD = 3.32)在家中或作为正常呼吸对照组的参与者完成其中一种为期两周的干预;他们报告了自己的年龄、身高、体重、体力活动水平、早泄症状和注意力调节。在HIIT组中,26名参与者每天进行7分钟的HIIT训练。在慢速呼吸组,25 名参与者每天进行 7 分钟的慢速呼吸练习,而正常呼吸组的 25 名参与者同样进行正常呼吸练习。所有参与者在干预前测量一次心率,干预后测量五次心率(间隔一分钟)。结果时间 × 干预交互作用显著,与正常呼吸组(M± SD = 17.68 ± 3.06、17.68 ± 3.15 和 17.44 ± 3.25)相比,HIIT 组在第 12、13 和 14 天的早泄症状水平较低(M± SD = 16.19 ± 3.45、15.96 ± 3.43 和 15.15 ± 3.62)。注意力调节水平越高,早泄症状越少。结论与对照组相比,为期两周的 HIIT 运动在减轻 PE 症状方面的疗效表明,它有可能成为治疗 PE 的一种新方法。
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引用次数: 0
Transcutaneous auricular vagus nerve stimulation enhanced emotional inhibitory control via increasing intrinsic prefrontal couplings 经皮耳廓迷走神经刺激通过增加前额叶内在耦合增强情绪抑制控制能力
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 DOI: 10.1016/j.ijchp.2024.100462
Siyu Zhu , Qi Liu , Xiaolu Zhang , Menghan Zhou , Xinqi Zhou , Fangyuan Ding , Rong Zhang , Benjamin Becker , Keith M Kendrick , Weihua Zhao

Background

Inhibitory control represents a core executive function that critically facilitates adaptive behavior and survival in an ever-changing environment. Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) has been hypothesized to improve behavioral inhibition performance, however the neurocomputational mechanism of taVNS-induced neuroenhancement remains elusive.

Method

In the current study, we investigated the efficacy of taVNS in a sham-controlled between-subject functional near infrared spectroscopy (fNIRS) experiment with an emotional face Go/No-Go paradigm in ninety healthy young adults.

Results

After a data quality check, eighty-two subjects were included in the final data analysis. Behaviorally, the taVNS improved No-Go response accuracy, together with computational modeling using Hierarchical Bayesian estimation of the Drift Diffusion Model (HDDM) indicating that it specifically reduced the information accumulation rate for Go responses, and this was negatively associated with increased accuracy of No-Go responses. On the neural level, taVNS enhanced engagement of the bilateral inferior frontal gyrus (IFG) during inhibition of angry expression faces and modulated functional couplings (FCs) within the prefrontal inhibitory control network. Mediation models revealed that taVNS-induced facilitation of inhibitory control was critically mediated by a decreased information accumulation for Go responses and concomitantly enhanced neurofunctional coupling between the inferior and orbital frontal cortex.

Discussion

Our findings demonstrate a potential for taVNS to improve emotional inhibitory control via reducing pre-potent responses and enhancing FCs within prefrontal inhibitory control networks, suggesting a promising therapeutic role in treating specific disorders characterized by inhibitory control deficits.

背景抑制控制是一种核心执行功能,对适应行为和在瞬息万变的环境中生存起着至关重要的作用。非侵入性经皮耳迷走神经刺激(taVNS)被认为可以改善行为抑制性能,但是taVNS诱导神经增强的神经计算机制仍然难以捉摸。方法在本研究中,我们在假对照受试者间功能性近红外光谱(fNIRS)实验中,以九十名健康的年轻人为研究对象,采用情绪化的人脸Go/No-Go范式,研究了taVNS的疗效。从行为学角度看,taVNS 提高了No-Go 反应的准确性,同时使用漂移扩散模型(HDDM)的层次贝叶斯估计进行的计算建模表明,taVNS 特别降低了Go 反应的信息积累率,而这与No-Go 反应准确性的提高呈负相关。在神经层面上,taVNS 增强了双侧额叶下回(IFG)在愤怒表情面孔抑制过程中的参与,并调节了前额叶抑制控制网络内的功能耦合(FCs)。讨论我们的研究结果表明,taVNS 有可能通过减少前能动反应和增强前额叶抑制控制网络内的功能耦合来改善情绪抑制控制,这表明taVNS 在治疗以抑制控制缺陷为特征的特定疾病方面具有良好的治疗作用。
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引用次数: 0
The mental health-related barriers and benefits to exercise in adults with and without chronic pain 患有和不患有慢性疼痛的成年人在锻炼时遇到的与心理健康有关的障碍和获得的益处
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 DOI: 10.1016/j.ijchp.2024.100471
Madeleine L. Connolly , Michaela C. Pascoe , Stephen C. Bowden , Anita B. Amorim , Kusal Goonewardena , Nicholas T. Van Dam

Background

Qualitative evidence points to the importance of both mental health-related barriers and benefits to exercise in chronic pain, yet this bidirectional relationship has not been established quantitatively.

Methods

89 adults with chronic pain (75 female, Age: M = 34.7, SD=13.2), and 89 demographically-matched individuals without chronic pain (73 female, Age: M = 32.0, SD=13.3) self-reported demographic and health information, mental health-related barriers and benefits to exercise, and leisure-time exercise activity.

Results

Adults with chronic pain had significantly higher scores on mental health-related barriers to exercise, and lower leisure-time exercise participation than adults without chronic pain. The groups did not differ on mental health-related benefits of exercise scores. Benefits scores positively predicted exercise, yet there was a significant negative interaction between pain and benefit scores, indicating a weaker positive relationship between benefits and exercise for adults with chronic pain than for those without chronic pain. Barrier scores significantly negatively predicted exercise engagement, but did not interact significantly with chronic pain.

Conclusion

Mental health-related barriers and benefits to exercise are important considerations when prescribing exercise for adults with chronic pain. Adults with chronic pain may require individualised support to address mental health-related barriers to leisure-time exercise.

背景定量证据表明,在慢性疼痛中,与心理健康有关的障碍和运动的益处都很重要,但这种双向关系尚未得到定量证实。结果与无慢性疼痛的成年人相比,患有慢性疼痛的成年人在与心理健康相关的运动障碍方面得分明显更高,而在闲暇时间参与运动的人数则更少。两组人在与心理健康相关的运动益处得分上没有差异。益处得分对运动有积极的预测作用,但疼痛与益处得分之间存在显著的负交互作用,这表明与无慢性疼痛的成年人相比,慢性疼痛成年人的益处与运动之间的积极关系较弱。与心理健康相关的运动障碍和运动益处是为患有慢性疼痛的成年人提供运动处方时的重要考虑因素。患有慢性疼痛的成年人可能需要个性化的支持,以解决与心理健康相关的业余锻炼障碍。
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引用次数: 0
Role of sexuality in women with chronic pain: Results from an Italian cross-sectional study on chronic headache, fibromyalgia, and vulvodynia 性在慢性疼痛妇女中的作用:意大利一项关于慢性头痛、纤维肌痛和外阴炎的横断面研究结果
IF 8.8 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-04-01 DOI: 10.1016/j.ijchp.2024.100472
Filippo Maria Nimbi, Martina Mesce, Erika Limoncin, Alessia Renzi, Federica Galli

Background/objectives

To compare sexual functioning, genital pain, and satisfaction among women diagnosed with various Chronic pain (CP) conditions. Additionally, it seeks to explore the role of sexual factors in predicting levels of central sensitization (indicative of CP-related mental and physical distress), physical, and mental quality of life (QoL) for each condition individually.

Methods

From April 2023 to January 2024, 1006 women categorized into five groups (Chronic Headache - CH; Fibromyalgia - FM, Vulvodynia - VU, Comorbidity group - CO, and Healthy Controls - HC) completed an online protocol.

Results

All groups reported sexual impairment: VU group exhibited the highest genital pain prevalence (97.93 %), followed by CO (74.29 %) and FM (55.91 %). ANCOVAs indicated lower sexual functioning scores for FM, VU, and CO compared to HC and CH. VU and CO reported lower satisfaction scores than other groups. Genital pain emerged as the primary predictor of central sensitization across all groups except controls. Regarding mental QoL, sexual satisfaction was significant for CH and CO, while genital pain and sexual satisfaction were significant for VU.

Conclusion

This study emphasizes the importance of integrating genito-pelvic pain assessment and addressing related sexual difficulties in CP diagnostics and care to enhance overall well-being and QoL.

背景/目的比较被诊断患有各种慢性疼痛(CP)的女性的性功能、生殖器疼痛和满意度。方法从 2023 年 4 月到 2024 年 1 月,1006 名女性完成了一项在线协议,她们被分为五组(慢性头痛组(CH)、纤维肌痛组(FM)、外阴炎组(VU)、合并症组(CO)和健康对照组(HC)):VU 组生殖器疼痛发生率最高(97.93%),其次是 CO 组(74.29%)和 FM 组(55.91%)。方差分析显示,与 HC 和 CH 相比,FM、VU 和 CO 的性功能得分较低。VU 和 CO 的满意度得分低于其他组别。除对照组外,生殖器疼痛是所有组别中枢敏化的主要预测因素。结论:本研究强调了将生殖器盆腔疼痛评估和解决相关性困难纳入 CP 诊断和护理以提高整体福祉和 QoL 的重要性。
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引用次数: 0
期刊
International Journal of Clinical and Health Psychology
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