International Journal of Clinical and Health Psychology最新文献

{"title":"Network structures of general, physical and psychological fatigue in patients with metastatic colorectal cancer: Implications for targeted coping strategies","authors":"Charlotte Grégoire ,&nbsp;Florence Cousson-Gélie ,&nbsp;Louise Baussard","doi":"10.1016/j.ijchp.2025.100590","DOIUrl":"10.1016/j.ijchp.2025.100590","url":null,"abstract":"<div><h3>Background</h3><div>Cancer-related fatigue (CRF) is a prevalent and debilitating symptom experienced by many patients, affecting both their physical and psychological well-being. This study aims to explore the network organization of three dimensions of CRF (i.e., general, physical, and psychological) and to examine how patient’s resources such as coping strategies interact with these distinct aspects of fatigue.</div></div><div><h3>Method</h3><div>This study involves data from a previous observational study on patients with metastatic colorectal cancer undergoing chemotherapy. Participants (<em>N</em> = 169) completed several questionnaires at baseline. Partial correlation network analysis was used to model the relationships between patients’ symptoms (i.e., CRF, emotional distress) and resources (i.e., perceived control of the illness, coping strategies, perceived social support), in three distinct networks, each of them including one dimension of fatigue (i.e., general, physical, or psychological). In each network, a core variable (i.e., a symptom or a resource) was identified based on the highest centrality indices.</div></div><div><h3>Results</h3><div>Coping strategies emerged as the core variable in the three networks, while depression was the symptom with the strongest association with CRF. These findings underline the interconnection between emotional state and fatigue, but most of all suggest the centrality of the patients’ resources, specifically coping strategies used to manage their symptoms, and their potential role in influencing the symptoms.</div></div><div><h3>Conclusion</h3><div>Our findings are expected to provide insights into targeted therapeutic approaches and enhance patient care. Understanding the complex interplay between the dimensions of fatigue and the coping strategies employed by patients is crucial for developing effective interventions.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100590"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding body image in adolescents with drunkorexia behaviors: The roles of body image disturbance, coping strategies and gender","authors":"Dora Bianchi ,&nbsp;Daniele Di Tata ,&nbsp;Stefania Sette ,&nbsp;Emiddia Longobardi ,&nbsp;Fiorenzo Laghi","doi":"10.1016/j.ijchp.2025.100584","DOIUrl":"10.1016/j.ijchp.2025.100584","url":null,"abstract":"<div><div>Drunkorexia consists of any calorie compensation or eating restrictive conduct enacted before, during, or immediately after alcohol intake. These behaviors raise many health concerns, but studies on adolescents are still limited. Specifically, understanding how body image impacts adolescent drunkorexia might be crucial for prevention and treatment. Following the multidimensional body image framework, this study investigated the role of various body image features (i.e., body image disturbance, adaptive and maladaptive body image coping) in explaining two types of drunkorexia behaviors in teenage girls and boys: (1) eating-related restrictive and compensative conducts; and (2) overexercising. The participants were 832 alcohol-drinking adolescents aged 15 to 20 years (48.6 % girls), who completed an online anonymous survey administered at school. A multigroup mediation model was estimated in line with the aims of the study. Body image disturbance symptoms were positively related to eating drunkorexia behaviors via the mediating effects of increasing maladaptive coping (avoidance and appearance fixing). However, the same relation was negative when the mediating effect of increasing adaptive coping (positive rational acceptance) was considered. Moreover, body image disturbance was positively associated with exercise-related drunkorexia behaviors via increasing appearance fixing coping. Finally, the indirect effect of body image disturbance on eating-related drunkorexia via appearance fixing was positive and significant only in girls (not in boys). These findings provide indications for implementing prevention and educational programs for schools, and for identifying core themes to address in clinical treatment and public health policies.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100584"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive training and retest learning effects on theta and alpha power in older and young adults: A perspective on the crunch hypothesis and the STAC-R model","authors":"Ludmiła Zając-Lamparska ,&nbsp;Emilia Zabielska-Mendyk ,&nbsp;Dariusz Zapała ,&nbsp;Paweł Augustynowicz","doi":"10.1016/j.ijchp.2025.100568","DOIUrl":"10.1016/j.ijchp.2025.100568","url":null,"abstract":"<div><div>According to the STAC-R model, scaffolding enhancement is achievable through various interventions. Indicating forms of compensatory scaffolding, the STAC-R model refers to phenomena described in other theoretical models, such as the enhanced fronto-parietal recruitment described in the CRUNCH hypothesis. The presented study investigated whether working memory training can induce compensatory scaffolding in older adults through increased prefrontal and parietal involvement (indicated by changes in theta and alpha power). The sample comprised 90 individuals, including 45 participants from the experimental (22 older and 23 young adults) and 45 from the passive control group (21 older and 24 young adults). The age range was 60–75 years for older adults and 20–35 years for young adults. We assessed the effects of a 12-session working memory training with the use of the adaptive n-back task on theta and alpha power measured in frontal midline and central-parietal areas by EEG in older and young adults during the n-back task performance at three difficulty levels. At the behavioral level, we found a positive, significant improvement in cognitive performance in young adults from experimental group. In contrast, the positive changes in older adults were too small to prove statistically significant. At the level of neuronal activity, we observed not a training effect but a retest effect. It was revealed primarily for theta oscillations in older adults and manifested by increased theta power with higher task demands and equalization of theta power of older and younger persons in the post-test. For alpha oscillations, the retest effect was negligible, and its only manifestation observed in older adults was a reduction in the dependence of alpha power on task difficulty. The study results indicate limited potential for improving WM performance in older adults compared to young adults. The presence of the retest learning effect, instead of the training effect, proved that familiarity with the task was crucial, rather than regular training of its performance. Changes observed in older adults in theta power can be considered positive, and these results are consistent with the CRUNCH hypothesis of a compensatory role for increased executive control involvement. In turn, changes in the alpha power in the same group should be considered rather maladaptive. Nevertheless, given the overall study findings, it can be concluded that although the behavioral effects of training are stronger in young adults, the changes in neuronal activity resulting from the retest learning effect are more marked in older adults.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100568"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Executive functions modulate conditioned fear extinction and reinstatement: The differential roles of shifting, updating, and inhibition","authors":"Wenzhao Zhang ,&nbsp;Yixia Huang ,&nbsp;Ying Mei ,&nbsp;Jinxia Wang ,&nbsp;Haoran Dou ,&nbsp;Yi Lei","doi":"10.1016/j.ijchp.2025.100581","DOIUrl":"10.1016/j.ijchp.2025.100581","url":null,"abstract":"<div><div>Conditioned fear learning is crucial for survival, and failure of fear extinction is closely related to the development of anxiety disorders. This study explores how different executive function (EF) subcomponents—shifting, updating, and inhibition—modulate conditioned fear extinction and reinstatement at both behavioral and neural levels. A total of 88 participants (age range: 17–23 years) completed the Stroop Task, Digit Size-Parity Switching Task, and Memory Updating Task to assess their executive function abilities. Participants underwent a classical fear extinction paradigm while their shock expectancy ratings and prefrontal cortical activity were recorded using functional near-infrared spectroscopy (fNIRS). Results indicated that individuals with higher shifting ability exhibited greater fear expectancy during fear acquisition <em>(β = -0.406, p = 0.032)</em> and reinstatement <em>(β = -0.834, p = 0.004)</em>, along with higher prefrontal cortex activity <em>(p &lt; 0.05)</em>, suggesting heightened responses to threatening stimuli. Individuals with higher updating ability showed a slower decrease in fear expectancy during the early extinction phase <em>(β = 0.038, p = 0.002)</em>, but maintained lower expectancy during the extinction recall phase <em>(β = -0.769, p = 0.006)</em>, indicating poorer extinction learning but better extinction memory retention. Individuals with higher updating ability also exhibited more extinction recall in the prefrontal cortex regions <em>(p_s &lt; 0.045)</em>. Individuals with higher inhibitory ability showed higher expectancy for CS+ and lower expectancy for CS− during extinction learning <em>(β = -0.409, p = 0.008)</em>, along with a slower decrease in fear expectancy <em>(β = -0.022, p = 0.055)</em>. Furthermore, individuals with higher inhibition ability showed lower PFC activity in immediate extinction <em>(p_s &lt; 0.0421)</em>, suggesting slower extinction learning but better regulation of safety cues. By clarifying the roles of these executive function components, our study highlights the cognitive mechanisms that could inform interventions aimed at improving fear extinction, offering potential strategies for mitigating anxiety-related disorders.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100581"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143924576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency-specific modulations for subcomponents of executive functions in the infra-slow frequency range —A combined O-tDCS and fNIRS study","authors":"Hang Yu,&nbsp;Xiaolong Liu,&nbsp;Chaojun Zheng,&nbsp;Zhuofan Wang,&nbsp;Miao Wang,&nbsp;Chi Zhang,&nbsp;Qiang Hao,&nbsp;Ronghan Liu,&nbsp;Yifeng Wang","doi":"10.1016/j.ijchp.2025.100575","DOIUrl":"10.1016/j.ijchp.2025.100575","url":null,"abstract":"<div><h3>Backgrounding</h3><div>The executive functions (EFs) involve multiple subcomponents including inhibition, updating, and shifting. These subcomponents are mediated by distinct brain networks, each linked to specific neural oscillations. Frequency-specific stimulation is a key approach to achieving precise intervention on different cognitive functions through affecting specific spatiotemporal organizations of brain networks.</div></div><div><h3>Objective</h3><div>We aimed to explore the modulation of different brain networks and EFs’ subcomponents by stimulation at frequencies of 0.02 Hz and 0.05 Hz, which are closely linked to whole-brain dynamics.</div></div><div><h3>Method</h3><div>In a randomized, placebo-controlled, cross-over study, we applied anodal oscillatory transcranial direct current stimulation (O-tDCS) to the left DLPFC to investigate the frequency-specific modulation on oxy-hemoglobin (HbO) and offline EF scores (Experiment 1, <em>N</em> = 54), as well as online EF scores (Experiment 2, <em>N</em> = 48).</div></div><div><h3>Result</h3><div>Near the stimulation frequency, brain signals were significantly enhanced. Specifically, an increase in power at 0.02 Hz was associated with enhanced inhibitory function, while an increase in power at 0.05 Hz was linked to decreased updating function. Compared to the sham condition, 0.02 Hz stimulation increases PLV within the frontal lobe, whereas 0.05 Hz increases PLV between the frontal and parietal lobes, indicating the presence of distinct spatiotemporal structures within cognitive-related brain networks.</div></div><div><h3>Conclusion</h3><div>The frequency-specific modulation of O-tDCS on brain networks and EF subcomponents suggests that different EFs are supported by brain networks with specific spatiotemporal architectures, bolstering the spectral fingerprint hypothesis of cognition. The spatiotemporal structure of cognitive-specific brain networks offers novel insights and targets for non-invasive interventions targeting diverse cognitive functions.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100575"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurobiological correlates of CBT response in OCD through the analysis of resting state networks","authors":"Mafalda Machado-Sousa ,&nbsp;Sara Bertolín ,&nbsp;Maria Picó-Pérez ,&nbsp;Ana Daniela Costa ,&nbsp;Rita Vieira ,&nbsp;Pino Alonso ,&nbsp;José M. Menchón ,&nbsp;Pedro Morgado ,&nbsp;Carles Soriano-Mas","doi":"10.1016/j.ijchp.2025.100585","DOIUrl":"10.1016/j.ijchp.2025.100585","url":null,"abstract":"<div><div>Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by obsessions and compulsions that cause significant distress and functional impairment. Cognitive-behavioral therapy (CBT), particularly involving exposure and response prevention (ERP), is a first-line treatment for OCD, though patient response varies widely. This study investigates the neurobiological correlates of CBT response in OCD, focusing on resting-state functional connectivity (rsFC) alterations. Twenty-five patients with OCD and 26 matched controls underwent resting-state fMRI at baseline and post-CBT. Results indicated decreased rsFC at baseline in OCD patients compared to controls within the higher visual (HVN), posterior salience (PSN), and language networks (LN). Following CBT, patients showed increased HVN connectivity, suggesting a normalization of the rsFC within this network. Additionally, we found an association between baseline LN rsFC and symptom improvement after CBT (the higher the connectivity, the more the symptom improvement), suggesting that LN connectivity could be a predictor of treatment response. These findings emphasize the role of sensory processing networks in OCD and highlight the ability of CBT to modulate brain connectivity.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100585"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of women with postpartum mental disorders in a day clinic mother-baby unit and the effect on child behavioural problems – A 1-year follow-up","authors":"Susann Steudte-Schmiedgen ,&nbsp;Luisa Bergunde ,&nbsp;Julia Frohberg ,&nbsp;Antje Bittner ,&nbsp;Anne Coenen ,&nbsp;Susan Garthus-Niegel ,&nbsp;Juliane Junge-Hoffmeister ,&nbsp;Kerstin Weidner","doi":"10.1016/j.ijchp.2025.100587","DOIUrl":"10.1016/j.ijchp.2025.100587","url":null,"abstract":"<div><h3>Background</h3><div>Postpartum mental disorders are highly prevalent with substantial impact on mother-child bonding and child development. While short-term benefits of an interaction-focused mother-baby treatment for maternal mental health are documented, little is known about the stability of these effects and their influence on child behavioural development.</div></div><div><h3>Method</h3><div>This prospective study included 348 women with postpartum mental disorders who received dyadic treatment at a specialized mother-baby day clinic. Maternal symptoms of depression (EPDS), anxiety (STAI-T), overall psychological distress (BSI-GSI) as well as parenting sense of competence (PSOC) were assessed at admission, discharge, and 1-year follow-up, along with diagnostic classification at admission. At 1-year follow-up, mothers (<em>n</em> = 164) completed the Child Behaviour Checklist (CBCL) to measure child behavioural problems.</div></div><div><h3>Results</h3><div>Maternal psychopathology and PSOC improved significantly from admission to discharge, with clinically meaningful effects. No additional improvements emerged from discharge to 1-year follow-up, except for a tentative reduction in anxiety symptoms. All outcome measures and outcome trajectories regarding anxiety symptoms and overall psychological distress varied by primary clinical diagnosis. Greater maternal symptom improvement from admission to 1-year follow-up was associated with fewer child behavioural problems. However, this effect was not found for symptom changes from admission to discharge when controlling for maternal symptoms at 1-year follow-up.</div></div><div><h3>Conclusions</h3><div>Interaction-focused treatment in a mother-baby day clinic may be associated with clinically meaningful improvements in maternal mental health outcomes up to 1-year follow-up. These long-term improvements may also relate to less child behavioural problems. However, the absence of a waiting list control group warrants cautious interpretation of findings.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100587"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of a breath robot intervention to reduce sleep problems in posttraumatic stress disorder: A randomized controlled study","authors":"Annett Lotzin ,&nbsp;Carlotta Reinhardt ,&nbsp;Michael Barthelmäs ,&nbsp;Isabelle Laskowsky","doi":"10.1016/j.ijchp.2025.100594","DOIUrl":"10.1016/j.ijchp.2025.100594","url":null,"abstract":"<div><div>Background: Patients with Posttraumatic stress disorder (PTSD) suffer from sleep problems. Robot interventions offer a novel approach to reducing these problems. However, it is unclear whether patients with PTSD accept and regularly use a robot intervention and whether it is effective. Objective: This randomized controlled study evaluated the feasibility of a novel breath robot intervention in PTSD patients. Methods: Thirty-one adults with PTSD according to DSM-V (PSSI-5) with impaired sleep (PSQI &gt; 5) were randomly assigned to a 4-week robot intervention (Somnox 2) with human breath simulation or to a 4-week robot intervention without human breath simulation. The primary feasibility outcome was the proportion of randomized participants providing outcome data at post-treatment. Secondary feasibility outcomes involved eligibility rate, recruitment speed, uptake, retention, treatment adherence, and dropout, clinical outcomes included sleep quality (PSQI), PTSD symptoms (PSSI-5), distress (PSS-10), and well-being (WHO-5). Results: Outcome data were provided by 96.8 %; eligibility rate was 75.6 %; 31 patients were recruited within 6 months; uptake and retention were 100 %; treatment adherence was 93.8 % in the intervention and 92.9 % in the active control group; dropout was 0 %. Distress decreased significantly more in the intervention group compared to the active control group (<em>SMD =</em> 0.67, 95 % CI 0.39, 0.94), but sleep quality, PTSD symptoms, and well-being did not improve significantly more. Conclusions: The use of a 4-week breath robot intervention was feasible and highly accepted in patients with severe PTSD. The breath robot intervention may reduce distress but may not be superior to a robot intervention without breath simulation for improving sleep and PTSD symptoms. Future trials should further determine the intervention’s clinical benefit.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100594"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep biomarkers of seasonal vulnerability in major depressive episodes: a clinical study using actigraphy and polysomnography","authors":"Julia MARUANI ,&nbsp;Lily VISSOUZE ,&nbsp;Marine AMBAR AKKAOUI ,&nbsp;Feriel ZEHANI ,&nbsp;Justine FRIJA ,&nbsp;Michel LEJOYEUX ,&nbsp;Marie-Pia d’ORTHO ,&nbsp;Pierre A. GEOFFROY","doi":"10.1016/j.ijchp.2025.100595","DOIUrl":"10.1016/j.ijchp.2025.100595","url":null,"abstract":"<div><div>Seasonal affective disorder or major depressive episode (MDE) with winter seasonal pattern is a severe form of recurrent depressive disorder persisting for at least 40 % of the year. This seasonal vulnerability may involve specific chronobiological and sleep regulation disturbances, however, actigraphy and polysomnography studies reported conflicting and inconclusive findings. In this context, we hypothesized that individuals with MDE who exhibit higher vulnerability to seasonal changes display distinct chronobiological and sleep regulation disturbances. We investigated how sleep and circadian rhythms, assessed through subjective markers (<em>N</em> = 254) and objective actigraphic (<em>N</em> = 96) and polysomnographic markers (<em>N</em> = 54)—varied in individuals with MDE according to their vulnerability to seasonal changes. To conduct this dimensional approach, that may be closer to the pathophysiology, we assessed the seasonal vulnerability using the Global Seasonality Score (GSS) from the Seasonal Patterns Assessment Questionnaire (SPAQ). The results revealed that greater seasonal vulnerability was correlated to increased excessive daytime sleepiness (Epworth scale), (<em>r</em> = 0.218, <em>p</em> &lt; 0.001), shorter REM sleep latency (<em>r</em> = -0.381, <em>p</em> = 0.005), (even when controlling for age using the Kupfer index (<em>r</em> = -0.452, <em>p</em> &lt; 0.001)), and shorter N1 sleep latency (<em>r</em> = -0.411, <em>p</em> = 0.002). The regression model retained only the polysomnographic markers—N1 sleep latency, REM sleep latency, Kupfer Index—independently and significantly associated to the GSS. This study confirms a link between seasonal vulnerability and shortened REM sleep latency, emphasizing that light and the photoperiod play a pivotal role in regulating the systems involved in REM sleep dysregulation in depressive disorders.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100595"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144270706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Altered resting-state functional connectivity in individuals at risk for Alzheimer’s disease: a longitudinal study","authors":"Pamela Chavarría-Elizondo ,&nbsp;Pablo Maturana-Quijada (1) ,&nbsp;Ignacio Martínez-Zalacaín ,&nbsp;Inés del Cerro ,&nbsp;Asier Juaneda-Seguí ,&nbsp;Andrés Guinea-Izquierdo ,&nbsp;Jordi Gascón-Bayarri ,&nbsp;Ramón Reñé-Ramírez ,&nbsp;Mikel Urretavizcaya ,&nbsp;Isidre Ferrer ,&nbsp;José M. Menchón ,&nbsp;Virginia Soria ,&nbsp;Carles Soriano-Mas","doi":"10.1016/j.ijchp.2025.100588","DOIUrl":"10.1016/j.ijchp.2025.100588","url":null,"abstract":"<div><h3>Background</h3><div>Resting-state functional connectivity magnetic resonance imaging (rs-fMRI) is a sensitive tool for detecting early brain changes associated with Alzheimer’s disease, even in its preclinical stages. Amnestic mild cognitive impairment (aMCI) and late-life depression (LLD) are two prevalent conditions in older adults that significantly elevate the risk of cognitive decline and dementia. This study aimed to elucidate the underlying neurobiological substrates by longitudinally identifying and comparing distinct connectivity patterns in aMCI subjects and LLD patients, and by examining the associations between these patterns and clinical measures of cognitive and mood impairments.</div></div><div><h3>Methods</h3><div>The study included three groups: 26 healthy controls (HCs), 15 individuals with aMCI, and 21 patients with LLD. All participants underwent rs-fMRI and neuropsychological assessments at baseline and at a 2-year follow-up. Functional connectivity was analyzed using a group Independent Component Analysis (ICA) model to investigate both group differences and longitudinal changes over time.</div></div><div><h3>Results</h3><div>At baseline, individuals with aMCI exhibited reduced functional connectivity in the precuneus, whereas LLD patients showed decreased connectivity in frontal, insular, and postcentral regions alongside increased connectivity in posterior parietal and cuneal cortices. Correlation analyses revealed that lower baseline insular connectivity predicted higher depressive symptoms at follow-up in aMCI subjects. In LLD, reduced baseline precuneus connectivity was associated with better two‐year outcomes in global cognition and long‐term memory.</div></div><div><h3>Conclusions</h3><div>This study provides evidence of distinct alterations in resting-state functional connectivity in individuals with aMCI and LLD, underscoring region-specific vulnerabilities that may contribute to cognitive decline and depressive symptomatology in older adults.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"25 2","pages":"Article 100588"},"PeriodicalIF":5.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144203649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}