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Abnormalities of cortical and subcortical spontaneous brain activity unveil mechanisms of disorders of consciousness and prognosis in patients with severe traumatic brain injury 皮层和皮层下自发脑活动异常揭示了严重脑外伤患者意识障碍和预后的机制
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-10-01 DOI: 10.1016/j.ijchp.2024.100528
Chang Li , Peng Chen , Yongbing Deng , Lei Xia , Xiaodong Wang , Min Wei , Xingdong Wang , Lun Dong , Jun Zhang

Objective

To investigate the spatial distribution characteristics of alterations in spontaneous brain activity in severe traumatic brain injury (sTBI) patients with disorders of consciousness (DOC), based on the mesocircuit theoretical framework, and to establish models for predicting recovery of consciousness.

Methods

Resting-state functional magnetic resonance imaging was employed to measure the mean fractional amplitude of low-frequency fluctuations (mfALFF) in sTBI patients with DOC and healthy controls, identifying differential brain regions for conducting gene and functional decoding analyses. Patients were classified into wake and DOC groups according to Extended Glasgow Outcome Score at 6 months. Furthermore, predictive models for consciousness recovery were developed using Nomogram and Linear Support Vector Machine (LSVM) based on mfALFF.

Results

In total, 28 sTBI patients with DOC and 30 healthy controls were included, with no significant baseline differences between groups (P > 0.05). The results revealed increased mfALFF of subcortical Ascending Reticular Activating System and decreased cortical mfALFF (default mode network) in DOC patients within the framework of the mesocircuit model (FDR_P < 0.001, Clusters > 100). The study identified 2080 differentially expressed genes associated with reduced brain activity regions, indicating mechanisms involving synaptic function, the oxytocin signaling pathway, and GABAergic processes in DOC formation. In addition, significantly higher mfALFF values were observed in the left angular gyrus, supramarginal gyrus, and inferior parietal lobule of DOC group compared to the wake group (AlphaSim_P < 0.01, Cluster > 19). The Nomogram prediction model highlighted the pivotal role of these regions' activity levels in prognosis (AUC = 0.90). Validation using LSVM demonstrated robust predictive performance with an AUC of 0.90 and positive predictive values of 80% for wake and 83% for DOC.

Conclusions

This study offered crucial insights underlying DOC in sTBI patients, demonstrating the dissociation between cortical and subcortical brain activities. The findings supported the use of mfALFF as a robust and non-invasive biomarker for evaluating brain function and predicting recovery outcomes.
方法采用静态功能磁共振成像技术测量严重创伤性脑损伤(sTBI)伴意识障碍(DOC)患者和健康对照组的低频波动平均分数振幅(mfALFF),确定差异脑区以进行基因和功能解码分析。根据 6 个月时的扩展格拉斯哥结果评分,将患者分为清醒组和 DOC 组。结果共纳入了28名患有DOC的sTBI患者和30名健康对照组患者,组间基线差异不显著(P> 0.05)。结果显示,在中枢回路模型框架内,DOC 患者皮层下上升网状激活系统的 mfALFF 增加,皮层 mfALFF(默认模式网络)减少(FDR_Plt; 0.001,群集数 >100)。研究发现了 2080 个与大脑活动减少区域相关的差异表达基因,表明 DOC 的形成机制涉及突触功能、催产素信号通路和 GABA 能过程。此外,与唤醒组相比,在 DOC 组的左侧角回、边际上回和顶叶下小叶观察到明显更高的 mfALFF 值(AlphaSim_P < 0.01,Cluster > 19)。Nomogram 预测模型强调了这些区域的活动水平在预后中的关键作用(AUC = 0.90)。使用 LSVM 进行的验证显示了强大的预测性能,AUC 为 0.90,唤醒和 DOC 的阳性预测值分别为 80% 和 83%。研究结果支持使用 mfALFF 作为评估大脑功能和预测康复结果的可靠、非侵入性生物标记物。
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引用次数: 0
Functional brain hubs are related to age: A primer study with rs-fMRI 大脑功能枢纽与年龄有关:利用 rs-fMRI 进行的初步研究
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-10-01 DOI: 10.1016/j.ijchp.2024.100517
María D. Figueroa-Jiménez , Cristina Cañete-Massé , Esteve Gudayol-Ferre , Geisa B. Gallardo-Moreno , Maribel Peró-Cebollero , Joan Guàrdia-Olmos

Background/Objective

Research on the ontogenetic development of brain networks using resting state has shown to be useful for understanding age-associated changes in brain connectivity. This work aimed to analyze the relationship between brain connectivity, age and intelligence.

Methods

A sample of 26 children and adolescents between 6 and 18 years of both sexes underwent a resting-state functional magnetic resonance imaging study. We estimated the values of fractional Amplitude low-frequency fluctuations (fALFF) and the values of Regional homogeneity (ReHo) in a voxelwise analysis to later correlate them with age and intelligence quotient (IQ).

Results

No significant correlations were found with IQ, but it was found that the fALFF values of the left precentral cortex (premotor cortex and supplementary motor area), as well as the ReHo values of the medial frontal gyrus, and the precentral cortex of the left hemisphere, correlate with age. Conclusions: Hubs related to various “task positive” networks closely related to cognitive functioning would present a development more related to age and relatively independent of individual differences in intelligence. These findings suggest that the premotor cortex and supplementary motor cortex could be a cortical hub that develops earlier than previously reported and that it would be more related to age than to intelligence level.
背景/目的利用静息状态对大脑网络的本体发育进行的研究表明,它有助于了解与年龄相关的大脑连通性变化。本研究旨在分析大脑连通性、年龄和智力之间的关系。方法对26名6至18岁的儿童和青少年进行了静息状态功能磁共振成像研究。我们在体素分析中估算了分数振幅低频波动(fALFF)值和区域同质性(ReHo)值,随后将其与年龄和智商(IQ)相关联。结果未发现与智商有明显相关性,但发现左半球前中央皮层(运动前皮层和辅助运动区)的 fALFF 值以及左半球额叶内侧回和前中央皮层的 ReHo 值与年龄相关。结论与认知功能密切相关的各种 "积极任务 "网络枢纽的发展与年龄的关系更为密切,而且与个体智力差异相对独立。这些研究结果表明,前运动皮层和辅助运动皮层可能是一个皮层枢纽,它的发育早于之前的报道,而且与年龄的关系大于与智力水平的关系。
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引用次数: 0
Virtual individual cognitive stimulation therapy (V-iCST): Mixed methods feasibility randomised controlled trial 虚拟个人认知刺激疗法(V-iCST):混合方法可行性随机对照试验
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-10-01 DOI: 10.1016/j.ijchp.2024.100523
Esther K. Hui , Victoria Tischler , Gloria H.Y. Wong , Luke Gibbor , Chiara Lousley , Georgia Bell , Maria Jelen , Tiffeny James , Rob Saunders , Charlotte Stoner , Elizabeth Sampson , Aimee Spector

Objective

Cognitive Stimulation Therapy (CST) is a dementia intervention shown to improve cognition and quality of life (QoL). Previous research on individual CST delivered by family carers showed no significant improvements in people with dementia. We aimed to evaluate the feasibility and acceptability of Virtual Individual Cognitive Stimulation Therapy (V-iCST) delivered by healthcare personnel.

Methods

Mixed methods feasibility randomised controlled trial. Thirty-four participants were randomly allocated to either 14 sessions of twice-weekly V-iCST (n = 17) or treatment as usual (n = 17) delivered over seven weeks. We assessed cognition, QoL, communication, and depressive symptoms pre/post-treatment. We conducted semi-structured qualitative interviews with participants and carers (n = 15) following V-iCST, analysed with thematic analysis.

Results

High levels of attendance, adherence, completion of outcomes, and moderate fidelity. There were no significant between-group changes, but there was a positive trend in cognition. Qualitative findings suggested that V-iCST was valued and convenient but can evoke negative emotions.

Conclusions

V-iCST was feasible and acceptable. Preliminary data indicate that V-iCST delivered by healthcare personnel might meet a critical gap through increasing access to those who cannot or prefer not to attend in-person CST/groups. The need for remote treatments and CST being the main psychosocial intervention emphasizes the need for definitive trial.
目的认知刺激疗法(CST)是一种痴呆症干预措施,被证明可以改善认知能力和生活质量(QoL)。以前关于由家庭照顾者提供个人 CST 的研究表明,该疗法对痴呆症患者没有明显改善。我们旨在评估由医护人员提供的虚拟个体认知刺激疗法(V-iCST)的可行性和可接受性。34名参与者被随机分配到为期七周、每周两次、每次14节的V-iCST治疗(17人)或常规治疗(17人)中。我们对治疗前后的认知、QoL、沟通和抑郁症状进行了评估。在 V-iCST 结束后,我们对参与者和照护者(n = 15)进行了半结构化定性访谈,并进行了主题分析。组间变化不明显,但认知能力呈积极趋势。定性研究结果表明,V-iCST 既有价值又方便,但会引起负面情绪。初步数据表明,由医护人员提供的 V-iCST 可为那些不能或不愿参加面对面 CST/小组的人提供更多机会,从而弥补了这一关键缺口。对远程治疗的需求以及 CST 作为主要的社会心理干预措施,强调了进行最终试验的必要性。
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引用次数: 0
Emotional dysregulation in relation to substance use and behavioral addictions: Findings from five separate meta-analyses 情绪失调与药物使用和行为成瘾的关系:五项独立荟萃分析的结果
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-01 DOI: 10.1016/j.ijchp.2024.100502
Alba González-Roz , Yasmina Castaño , Andrea Krotter , Angie Salazar-Cedillo , Elena Gervilla

Background/objective

Emotional dysregulation (ED) is a transdiagnostic variable underlying various psychiatric disorders, including addictive behaviors (ABs). This meta-analysis examines the relationship between ED and ABs (alcohol, tobacco, cannabis, gambling, and gaming), and indicators of AB engagement (frequency, quantity/time of use, severity, and problems).

Method

Searches were conducted in PubMed, Scopus, WoS, and PsycINFO. Five separate meta-analysis were run using random-effects models. Moderators (age, sex, continental region, and sample type; community vs. clinical), and publication bias were evaluated.

Results

A total of 189 studies (N = 78,733; 51.29 % women) were identified. ED was significantly related to all ABs. Problems and severity indicators exhibited the largest effects (r’s .118-.372, all p <.023). There were larger effect sizes for cannabis problems (r = .372), cannabis severity (r = .280), gaming severity (r = .280), gambling severity (r = .245), gambling problems (r = .131), alcohol problems (r = .237), alcohol severity (r = .204), and severity of nicotine dependence (r = .118). Lack of impulse control exhibited some of the largest effects in relation to ABs. Clinical samples of cannabis users vs. community-based exhibited larger magnitude of associations.

Conclusions

Interventions targeting ABs should address lack of strategies and impulsive behaviors as an emotion regulation strategy specifically, as it is a common risk factor for ABs.

背景/目的情绪失调(ED)是导致包括成瘾行为(ABs)在内的各种精神疾病的一个跨诊断变量。本荟萃分析研究了 ED 与成瘾行为(酒精、烟草、大麻、赌博和游戏)之间的关系,以及成瘾行为的参与指标(使用频率、数量/时间、严重程度和问题)。使用随机效应模型分别进行了五项荟萃分析。对调节因素(年龄、性别、大陆地区和样本类型;社区与临床)和发表偏差进行了评估。 结果共发现 189 项研究(N = 78,733; 51.29 % 为女性)。ED与所有ABs均有明显关系。问题和严重程度指标的影响最大(r's .118-.372, all p <.023)。大麻问题(r = .372)、大麻严重程度(r = .280)、游戏严重程度(r = .280)、赌博严重程度(r = .245)、赌博问题(r = .131)、酒精问题(r = .237)、酒精严重程度(r = .204)和尼古丁依赖严重程度(r = .118)的效应较大。冲动控制能力的缺乏对 ABs 的影响最大。结论针对ABs的干预措施应特别针对作为情绪调节策略的缺乏策略和冲动行为,因为这是ABs的常见风险因素。
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引用次数: 0
Effects of two-person synchronized cycling exercise on interpersonal cooperation: A near-infrared spectroscopy hyperscanning study 双人同步自行车运动对人际合作的影响:近红外光谱超扫描研究
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-01 DOI: 10.1016/j.ijchp.2024.100492
Huiling Wang , Lin Li

Objective

Although psychological research indicating the synchronous activities can promote interpersonal cooperation, thus far there is no direct evidence that two-person synchronous exercise effectively enhances interpersonal cooperative behaviors in Physical exercise field. This suggests that, although synchronization phenomenon is widespread in sports and is considered a potential tool for enhancing teamwork, its specific effects and functioning mechanisms still need to be clarified by further scientific research. This study intends to use two-person synchronized cycling exercise to investigate the synchronized exercise effect on interpersonal cooperative behavior and its underlying neural mechanisms.

Methods

Eighty college students without regular exercise habits will be randomly assigned to the experimental group (10 male dyads and 10 female dyads) and the control group (10 male dyads and 10 female dyads). During the experiment, dyads in the experimental group performed a 30-minute synchronized cycling exercise with synchronized pedaling movements; dyads in the control group rested sedentary in the same environment for 30 minutes. Interpersonal cooperative behavior was assessed with the Prisoner's Dilemma task, and the interpersonal neural synchronization(INS) data were collected in the prefrontal cortex using near-infrared hyperscanning.

Results

This study compared behavior and brain activity before and after synchronous exercise. Behavioral results revealed that, compared to pre-exercise, dyads in the post-exercise had higher average cooperation rates, higher cooperation efficiency and shorter cooperation response times. Compared to post-sedentary, dyads in the post-exercise had shorter cooperation response times and higher cooperation efficiency. Furthermore, brain data showed that,compared to pre-exercise, dyads in the post-exercise had stronger INS in the dorsolateral prefrontal cortex(DLPFC), whereas the dyads in the post-exercise had stronge INS in the DLPFC compared to post-sedentary. After controlling for dyads' anxiety and mood states, this study also found a marginally significant negative correlation between INS differences in the left DLPFC and cooperation response time differences.

Conclusions

This research confirms, from both behavioral and neuroscience perspectives, that one synchronization cycle can significantly enhance interpersonal cooperative behavior, and this positive effect is closely associated with increased INS in the left DLPFC. This study provides new insights into understanding how positive interactive exercises promote interpersonal cooperation through specific neural mechanisms.

目的 虽然心理学研究表明同步活动能促进人际合作,但迄今为止,在体育锻炼领域还没有直接证据表明两人同步运动能有效增强人际合作行为。这表明,虽然同步现象在体育运动中广泛存在,并被认为是增强团队合作的潜在工具,但其具体效果和作用机制仍有待进一步的科学研究来阐明。本研究拟采用双人同步自行车运动的方法,探讨同步运动对人际合作行为的影响及其潜在的神经机制。方法将八名没有规律运动习惯的大学生随机分配到实验组(男双人组 10 人,女双人组 10 人)和对照组(男双人组 10 人,女双人组 10 人)。在实验过程中,实验组的两人一组进行 30 分钟的同步自行车运动,同步蹬踏;对照组的两人一组在相同的环境中静坐休息 30 分钟。结果这项研究比较了同步运动前后的行为和大脑活动。行为结果显示,与运动前相比,运动后的二人组有更高的平均合作率、更高的合作效率和更短的合作反应时间。与运动后相比,运动后的双人合作反应时间更短,合作效率更高。此外,大脑数据显示,与运动前相比,运动后的双人组在背外侧前额叶皮层(DLPFC)有更强的INS,而与运动后相比,运动后的双人组在背外侧前额叶皮层(DLPFC)有更强的INS,而与运动后相比,运动后的双人组在背外侧前额叶皮层(DLPFC)有更强的INS。在控制了两人的焦虑和情绪状态后,本研究还发现左侧 DLPFC 的 INS 差异与合作反应时间差异之间存在微小的显著负相关。结论本研究从行为学和神经科学的角度证实,一个同步周期可以显著增强人际合作行为,而这种积极效应与左侧 DLPFC INS 的增加密切相关。这项研究为了解积极的互动练习如何通过特定的神经机制促进人际合作提供了新的见解。
{"title":"Effects of two-person synchronized cycling exercise on interpersonal cooperation: A near-infrared spectroscopy hyperscanning study","authors":"Huiling Wang ,&nbsp;Lin Li","doi":"10.1016/j.ijchp.2024.100492","DOIUrl":"10.1016/j.ijchp.2024.100492","url":null,"abstract":"<div><h3>Objective</h3><p>Although psychological research indicating the synchronous activities can promote interpersonal cooperation, thus far there is no direct evidence that two-person synchronous exercise effectively enhances interpersonal cooperative behaviors in Physical exercise field. This suggests that, although synchronization phenomenon is widespread in sports and is considered a potential tool for enhancing teamwork, its specific effects and functioning mechanisms still need to be clarified by further scientific research. This study intends to use two-person synchronized cycling exercise to investigate the synchronized exercise effect on interpersonal cooperative behavior and its underlying neural mechanisms.</p></div><div><h3>Methods</h3><p>Eighty college students without regular exercise habits will be randomly assigned to the experimental group (10 male dyads and 10 female dyads) and the control group (10 male dyads and 10 female dyads). During the experiment, dyads in the experimental group performed a 30-minute synchronized cycling exercise with synchronized pedaling movements; dyads in the control group rested sedentary in the same environment for 30 minutes. Interpersonal cooperative behavior was assessed with the Prisoner's Dilemma task, and the interpersonal neural synchronization(INS) data were collected in the prefrontal cortex using near-infrared hyperscanning.</p></div><div><h3>Results</h3><p>This study compared behavior and brain activity before and after synchronous exercise. Behavioral results revealed that, compared to pre-exercise, dyads in the post-exercise had higher average cooperation rates, higher cooperation efficiency and shorter cooperation response times. Compared to post-sedentary, dyads in the post-exercise had shorter cooperation response times and higher cooperation efficiency. Furthermore, brain data showed that,compared to pre-exercise, dyads in the post-exercise had stronger INS in the dorsolateral prefrontal cortex(DLPFC), whereas the dyads in the post-exercise had stronge INS in the DLPFC compared to post-sedentary. After controlling for dyads' anxiety and mood states, this study also found a marginally significant negative correlation between INS differences in the left DLPFC and cooperation response time differences.</p></div><div><h3>Conclusions</h3><p>This research confirms, from both behavioral and neuroscience perspectives, that one synchronization cycle can significantly enhance interpersonal cooperative behavior, and this positive effect is closely associated with increased INS in the left DLPFC. This study provides new insights into understanding how positive interactive exercises promote interpersonal cooperation through specific neural mechanisms.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100492"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000577/pdfft?md5=fc996444c8e238d32802b0afc1ada94f&pid=1-s2.0-S1697260024000577-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensori-motor neurofeedback improves inhibitory control and induces neural changes: a placebo-controlled, double-blind, event-related potentials study 感觉运动神经反馈改善抑制控制并诱导神经变化:一项安慰剂对照、双盲、事件相关电位研究
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-01 DOI: 10.1016/j.ijchp.2024.100501
Clémence Dousset , Florent Wyckmans , Thibaut Monseigne , Lauréline Fourdin , Romane Boulanger , Sonia Sistiaga , Anaïs Ingels , Hendrik Kajosch , Xavier Noël , Charles Kornreich , Salvatore Campanella

Background/Objective

Inhibition is crucial for controlling behavior and is impaired in various psychopathologies. Neurofeedback holds promise in addressing cognitive deficits, and experimental research is essential for identifying its functional benefits. This study aimed to investigate whether boosting sensorimotor activity (SMR) improves inhibitory control in a final sample of healthy individuals (N = 53), while exploring the underlying neurophysiological mechanism.

Method

Participants were randomly divided into two groups: one receiving SMR neurofeedback training to enhance sensorimotor activity within the 12–15 Hz frequency range, and the other receiving sham feedback. Inhibition performance and neural correlates were evaluated with a Go-NoGo task before (T0) and after (T1) 10 neurofeedback sessions using event-related potentials. Data were analyzed via ANOVAs and regression analyses.

Results

Compared to placebo, the active group demonstrated higher absolute SMR power (p = 0.040) and improvements in inhibitory control, including faster response times and fewer inhibition errors (p < 0.001, d = 6.06), associated with a larger NoGoP3d amplitude (p < 0.001, d = 3.35). A positive correlation between the increase in SMR power and the rise in NoGoP3d amplitude (β=0.46, p = 0.015) explains 21 % of the observed variance.

Conclusions

Uptraining SMR power is linked to heightened utilization of neural resources for executing optimal inhibition responses. These results uphold its effectiveness in cognitive rehabilitation.

背景/目的抑制是控制行为的关键,在各种精神病症中都会受到损害。神经反馈有望解决认知缺陷问题,而实验研究对于确定其功能性益处至关重要。本研究旨在调查增强感觉运动活动(SMR)是否能改善最终样本健康人(N = 53)的抑制控制能力,同时探索其潜在的神经生理机制。方法将参与者随机分为两组:一组接受 SMR 神经反馈训练以增强 12-15 Hz 频率范围内的感觉运动活动,另一组接受假反馈。在 10 次神经反馈训练之前(T0)和之后(T1),使用事件相关电位对抑制性能和神经相关性进行评估。结果与安慰剂相比,主动组显示出更高的绝对 SMR 功率(p = 0.040)和抑制控制的改善,包括更快的反应时间和更少的抑制错误(p < 0.001,d = 6.06),与更大的 NoGoP3d 振幅(p < 0.001,d = 3.35)相关。SMR功率的增加与NoGoP3d振幅的增加之间的正相关(β=0.46,p=0.015)解释了21%的观察变异。这些结果支持了其在认知康复中的有效性。
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引用次数: 0
Exploring psychosomatic congruence: The effect of focusing on body parts as a body-oriented mentalization process 探索心身一致性:关注身体部位作为以身体为导向的心智化过程的效果
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-01 DOI: 10.1016/j.ijchp.2024.100488
Idit Shalev , Erez Yaakobi

Background/Objective

: Patients with somatic symptoms are considered to have a deficiency in body-oriented mentalization; that is, the ability to perceive and interpret bodily sensations in relation to psychological states. We introduce the novel concept of psychosomatic congruence—the alignment of physical sensations with cognition and emotional states, which leads to behaviors that synchronize physical manifestations with emotional experiences and internal reflections. Despite its clinical relevance, this concept has not been empirically examined. Three experiments investigated the effects of psychosomatic congruence on the mental content of associations, autobiographical memories, and the accessibility of negative-related words. Grounded in theories of embodied cognition and interoception, we hypothesized that psychosomatic congruence could be facilitated through an initiated interoceptive task.

Methods

: Three pre-registered experiments involving 318 participants were conducted. Participants were asked to identify and label their most pleasant and unpleasant body parts, and then engaged in tasks involving associations with neutral words, memory retrieval, and the accessibility of negative-related words under varying conditions of mortality salience.

Results

: Focusing on the most pleasant body part, as compared to the most unpleasant, led to more positive associations with neutral words, enhanced positive memory retrieval, and reduced accessibility of negatively related words.

Conclusions

: These findings provide evidence that initiating an interoceptive task by focusing attention on body parts can induce congruent mental content. They offer insights into body-oriented mentalization and suggest that emotional distress may potentially be regulated by deliberately focusing on pleasant body parts.

背景/目的:有躯体症状的患者被认为缺乏以身体为导向的心理能力,即感知和解释与心理状态相关的身体感觉的能力。我们提出了 "心身一致性 "这一新颖概念--身体感觉与认知和情绪状态相一致,从而导致身体表现与情绪体验和内心反思同步的行为。尽管这一概念与临床息息相关,但还没有人对其进行过实证研究。三项实验研究了心身一致性对联想的心理内容、自传体记忆和负面相关词汇的可及性的影响。基于具身认知和内感知理论,我们假设通过启动内感知任务可以促进心身一致性:我们进行了三次预先登记的实验,共有 318 人参加。实验要求参与者识别并标注他们最愉快和最不愉快的身体部位,然后在不同的死亡率显著性条件下,参与涉及中性词联想、记忆检索和负面相关词的可及性的任务:结果:与最令人不愉快的身体部位相比,关注最令人愉快的身体部位会让人对中性词产生更多积极的联想,增强积极的记忆检索,并降低负面相关词语的可及性:这些发现提供了证据,证明通过将注意力集中在身体部位来启动互感任务,可以诱发一致的心理内容。这些研究结果提供了对以身体为导向的心智化的见解,并表明情绪困扰有可能通过刻意关注令人愉悦的身体部位而得到调节。
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引用次数: 0
The influence of partner trustworthiness and relationship closeness on interpersonal trust in individuals with attachment anxiety: An ERP study 伴侣的可信度和关系亲密程度对依恋焦虑症患者人际信任的影响:ERP研究
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-01 DOI: 10.1016/j.ijchp.2024.100494
Xiuqin Bao, Mengke Zhang, Xu Chen

Interpersonal trust (IT) is a combination of individuals’ cognitive evaluations of others’ trustworthiness and affective considerations related to the relationships. Individuals’ trust decisions overly relying on the intimacy of the relationship can be detrimental to their socialization. Attachment styles provide a theoretical framework for explaining individual differences in IT and the balance between cognition control and affective evaluation in social-information processing. However, it remains unclear whether high attachment anxiety (AX) individuals with high interpersonal needs exhibit non-socially adaptive trust decisions, characterized by an over-reliance on relationship closeness (RC), independent of partner trustworthiness (PT). A coin-toss task, combined with event-related potential (ERP), was utilized to explore the performance and temporal characteristics of trust decision-making among individuals with high and low AX under the influence of the two factors. The behavioral results showed that high-AX individuals tended to trust close others regardless of their trustworthiness, while low-AX individuals only trusted close others under low-PT conditions, with no differences in RC for high-PT. The ERP results revealed that high-AX individuals exhibited an enhanced positive P1 by low-trust partners, only discerning differences in RC for high-trust partners (more negative N2 by strangers than friends), reflecting poor conflict-detection abilities confronted with low-trust partners. Low-AX individuals’ neural activity showed higher consistency with their behavioral performance, indicating that trust in close others under low-trust conditions was due to the fewer conflicts elicited and higher expectations of them, reflecting smaller N2 and larger P3. Overall, these findings indicated that high-AX individuals’ IT decision-making was primarily influenced by their reliance on affective evaluation in information processing and weaker cognitive-control abilities, highlighting the contribution of attachment to social-information processing.

人际信任(IT)是个人对他人可信度的认知评价和与人际关系相关的情感考虑的结合。个体的信任决策过度依赖于关系的亲密程度可能会对其社会化造成损害。依恋风格提供了一个理论框架来解释个体在信息技术方面的差异,以及在社会信息处理过程中认知控制和情感评价之间的平衡。然而,高度依恋焦虑(AX)的高人际需求个体是否会表现出非社会适应性的信任决策,其特点是过度依赖关系亲密性(RC),而与伴侣的可信度(PT)无关,这一点仍不清楚。研究利用抛硬币任务和事件相关电位(ERP),探讨了高AX和低AX个体在这两个因素影响下的信任决策表现和时间特征。行为结果表明,高AX个体倾向于信任亲密的他人,无论其可信度如何;而低AX个体只在低PT条件下信任亲密的他人,高PT条件下的RC没有差异。ERP结果显示,高AX个体对低信任度伙伴表现出更强的正P1,仅对高信任度伙伴的RC有辨别差异(对陌生人的负N2多于对朋友的负N2),这反映出他们面对低信任度伙伴时冲突检测能力较差。低信任度个体的神经活动与其行为表现的一致性更高,这表明在低信任度条件下,对亲密他人的信任是由于引发的冲突更少以及对冲突的期望值更高,反映出较小的 N2 和较大的 P3。总之,这些研究结果表明,高信任度个体的信息技术决策主要受其在信息处理中对情感评价的依赖性和较弱的认知控制能力的影响,突出了依恋对社会信息处理的贡献。
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引用次数: 0
Increased intraindividual variability (IIV) in reaction time is the earliest indicator of cognitive change in MS: A two-year observational study 反应时间的个体内变异性(IIV)增加是多发性硬化症认知变化的最早指标:一项为期两年的观察研究
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-01 DOI: 10.1016/j.ijchp.2024.100486
Giuseppina Pilloni , T. Charles Casper , Soe Mar , Jayne Ness , Teri Schreiner , Michael Waltz , Emmanuelle Waubant , Bianca Weinstock-Guttman , Yolanda Wheeler , Lauren Krupp , Leigh Charvet

Background

Cognitive decline in multiple sclerosis (MS) is common, but unpredictable, and increases with disease duration. As such, early detection of cognitive decline may improve the effectiveness of interventions. To that end, the Symbol Digit Modalities Test (SDMT) is effective in detecting slow processing speed as it relates to cognitive impairment, and intraindividual variability (IIV) observed in trials assessing continuous reaction time (RT) may be a useful indicator of early cognitive changes. Here, we will assess cognitive IIV changes in adults with early MS.

Methods

Adults with relapsing-remitting MS (RRMS), <11 years since diagnosis, were recruited nationally. Baseline and two-year follow-up assessments included Brief International Cognitive Assessment in MS (BICAMS) and Cogstate computerized tests. Intraindividual variability in RT was calculated from psychomotor tasks and data were age-normalized.

Results

A total of 44 of the 66 participants completed follow-up (mean age, 34.0 ± 5.5 years; 66 % female; mean disease duration, 4.1 ± 2.9 years; median Expanded Disability Status Scale (EDSS) score, 1.5 [0 to 6.0]). Participants were grouped by SDMT z-score median split. Groups did not differ in demographics or clinical features. The higher baseline SDMT group was faster (p = 0.05) in RT and less variable (lower IIV, p = 0.001). At the two-year follow-up, the higher SDMT group showed increased variability (p = 0.05) compared to the lower SDMT group, with no significant RT or BICAMS changes.

Conclusions

In early MS, higher SDMT performance at baseline is associated with less cognitive variability but may indicate susceptibility to increased variability over time, highlighting the importance of monitoring IIV for early cognitive changes.

背景多发性硬化症(MS)患者的认知能力下降很常见,但无法预测,而且会随着病程的延长而加剧。因此,早期发现认知能力下降可提高干预措施的有效性。为此,符号数字模型测试(SDMT)可有效检测与认知功能障碍有关的处理速度缓慢,而在评估连续反应时间(RT)的试验中观察到的个体内变异性(IIV)可能是早期认知功能变化的有用指标。在此,我们将评估成人早期多发性硬化症患者的认知IIV变化。方法在全国范围内招募复发缓解型多发性硬化症(RRMS)患者,确诊时间为11年。基线和两年随访评估包括多发性硬化症简明国际认知评估(BICAMS)和Cogstate计算机测试。结果 66名参与者中共有44人完成了随访(平均年龄为34.0 ± 5.5岁;66%为女性;平均病程为4.1 ± 2.9年;中位残疾状况扩展量表(EDSS)评分为1.5 [0 - 6.0])。参与者按 SDMT z 评分中位数进行分组。各组在人口统计学或临床特征方面没有差异。基线SDMT较高的一组患者的RT速度较快(p = 0.05),变异性较小(IIV较低,p = 0.001)。结论 在早期多发性硬化症中,基线 SDMT 表现较高与认知变异性较低有关,但可能表明随着时间的推移,变异性容易增加,这突出了监测 IIV 早期认知变化的重要性。
{"title":"Increased intraindividual variability (IIV) in reaction time is the earliest indicator of cognitive change in MS: A two-year observational study","authors":"Giuseppina Pilloni ,&nbsp;T. Charles Casper ,&nbsp;Soe Mar ,&nbsp;Jayne Ness ,&nbsp;Teri Schreiner ,&nbsp;Michael Waltz ,&nbsp;Emmanuelle Waubant ,&nbsp;Bianca Weinstock-Guttman ,&nbsp;Yolanda Wheeler ,&nbsp;Lauren Krupp ,&nbsp;Leigh Charvet","doi":"10.1016/j.ijchp.2024.100486","DOIUrl":"https://doi.org/10.1016/j.ijchp.2024.100486","url":null,"abstract":"<div><h3>Background</h3><p>Cognitive decline in multiple sclerosis (MS) is common, but unpredictable, and increases with disease duration. As such, early detection of cognitive decline may improve the effectiveness of interventions. To that end, the Symbol Digit Modalities Test (SDMT) is effective in detecting slow processing speed as it relates to cognitive impairment, and intraindividual variability (IIV) observed in trials assessing continuous reaction time (RT) may be a useful indicator of early cognitive changes. Here, we will assess cognitive IIV changes in adults with early MS.</p></div><div><h3>Methods</h3><p>Adults with relapsing-remitting MS (RRMS), &lt;11 years since diagnosis, were recruited nationally. Baseline and two-year follow-up assessments included Brief International Cognitive Assessment in MS (BICAMS) and Cogstate computerized tests. Intraindividual variability in RT was calculated from psychomotor tasks and data were age-normalized.</p></div><div><h3>Results</h3><p>A total of 44 of the 66 participants completed follow-up (mean age, 34.0 ± 5.5 years; 66 % female; mean disease duration, 4.1 ± 2.9 years; median Expanded Disability Status Scale (EDSS) score, 1.5 [0 to 6.0]). Participants were grouped by SDMT z-score median split. Groups did not differ in demographics or clinical features. The higher baseline SDMT group was faster (<em>p</em> = 0.05) in RT and less variable (lower IIV, <em>p</em> = 0.001). At the two-year follow-up, the higher SDMT group showed increased variability (<em>p</em> = 0.05) compared to the lower SDMT group, with no significant RT or BICAMS changes.</p></div><div><h3>Conclusions</h3><p>In early MS, higher SDMT performance at baseline is associated with less cognitive variability but may indicate susceptibility to increased variability over time, highlighting the importance of monitoring IIV for early cognitive changes.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100486"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000516/pdfft?md5=a1bdf32dc4c8ad1056cd6835cd6cb381&pid=1-s2.0-S1697260024000516-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141606312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital empowerment in mental health: A meta-analysis of internet-based interventions for enhancing mental health literacy 心理健康中的数字赋权:基于互联网的心理健康知识普及干预措施荟萃分析
IF 5.3 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-01 DOI: 10.1016/j.ijchp.2024.100489
Qiang Chen , Ziyi Zhao , Jiamin Bao , Jie Lin , Wei Li , Yinyin Zang

Background

Poor mental health literacy (MHL) in the global population significantly contributes to the treatment gap associated with mental disorders. In the digital age, leveraging Internet-based MHL interventions offers scalability and broader accessibility. This meta-analysis aimed to evaluate the effects of Internet-based interventions in improving MHL and mental health.

Method

Up to Feb 2024, seven databases were searched for Internet-based interventions on MHL (knowledge, stigma, help-seeking attitudes and intentions) and mental disorders (general distress, anxiety, and depressive symptoms). The random-effects meta-analyses at post-intervention and long-term follow-up assessments were performed.

Results

Twenty-nine eligible studies involving 11,582 participants were included. Significant positive effects were observed across various domains: knowledge increase (immediate: g = 0.459, 95 %CI: 0.285 to 0.634; follow-up: g = 0.487, 95 %CI: 0.348 to 0.626), immediate stigma reduction (g = -0.332, 95 %CI: -0.479 to -0.186), immediate enhancement of help-seeking attitudes (g = 0.168, 95 %CI: 0.046 to 0.3291) and help-seeking intentions (g = 0.135, 95 %CI: 0.072 to 0.198), as well as immediate mental health improvements (g = -0.074, 95 %CI: -0.115 to -0.033).

Conclusion

Overall, these findings underscore the promising effects of internet-based interventions in improving MHL and mental health, while maintaining these effects over time remains challenging, particularly in reducing stigma and promoting long-term help-seeking behaviors. Addressing methodological limitations, adopting a more interactive approach, and implementing targeted interventions are crucial to maximizing the effectiveness and advancing mental health care worldwide.

全球人口的心理健康素养(MHL)低下,是造成与精神障碍相关的治疗差距的重要原因。在数字时代,利用基于互联网的 MHL 干预措施具有可扩展性和更广泛的可及性。这项荟萃分析旨在评估基于互联网的干预措施在改善 MHL 和心理健康方面的效果。截至 2024 年 2 月,我们在七个数据库中搜索了基于互联网的 MHL(知识、耻辱感、求助态度和意愿)和精神障碍(一般痛苦、焦虑和抑郁症状)干预措施。对干预后和长期随访评估进行了随机效应荟萃分析。共纳入了 29 项符合条件的研究,涉及 11,582 名参与者。在各个领域都观察到了显著的积极效果:知识增加(即时:= 0.459,95 %CI:0.285 至 0.634;随访:= 0.487,95 %CI:0.348 至 0.626)、即时污名化减少(= -0.332,95 %CI:-0.479 至 -0.186)、即时增强对心理治疗的满意度(= 0.489,95 %CI:-0.479 至 -0.186)、即时增强对心理治疗的满意度(= -0.332,95 %CI:-0.479 至 -0.186)。186),求助态度(= 0.168,95 %CI:0.046 至 0.3291)和求助意向(= 0.135,95 %CI:0.072 至 0.198)立即得到改善,心理健康也立即得到改善(= -0.074,95 %CI:-0.115 至 -0.033)。总之,这些研究结果表明,基于互联网的干预措施在改善多发性硬化症和心理健康方面具有良好的效果,但长期保持这些效果仍具有挑战性,尤其是在减少耻辱感和促进长期求助行为方面。解决方法上的局限性、采用互动性更强的方法以及实施有针对性的干预措施,对于在全球范围内最大限度地提高干预效果和推进心理保健工作至关重要。
{"title":"Digital empowerment in mental health: A meta-analysis of internet-based interventions for enhancing mental health literacy","authors":"Qiang Chen ,&nbsp;Ziyi Zhao ,&nbsp;Jiamin Bao ,&nbsp;Jie Lin ,&nbsp;Wei Li ,&nbsp;Yinyin Zang","doi":"10.1016/j.ijchp.2024.100489","DOIUrl":"10.1016/j.ijchp.2024.100489","url":null,"abstract":"<div><h3>Background</h3><p>Poor mental health literacy (MHL) in the global population significantly contributes to the treatment gap associated with mental disorders. In the digital age, leveraging Internet-based MHL interventions offers scalability and broader accessibility. This meta-analysis aimed to evaluate the effects of Internet-based interventions in improving MHL and mental health.</p></div><div><h3>Method</h3><p>Up to Feb 2024, seven databases were searched for Internet-based interventions on MHL (knowledge, stigma, help-seeking attitudes and intentions) and mental disorders (general distress, anxiety, and depressive symptoms). The random-effects meta-analyses at post-intervention and long-term follow-up assessments were performed.</p></div><div><h3>Results</h3><p>Twenty-nine eligible studies involving 11,582 participants were included. Significant positive effects were observed across various domains: knowledge increase (immediate: <em>g</em> = 0.459, 95 %CI: 0.285 to 0.634; follow-up: <em>g</em> = 0.487, 95 %CI: 0.348 to 0.626), immediate stigma reduction (<em>g</em> = -0.332, 95 %CI: -0.479 to -0.186), immediate enhancement of help-seeking attitudes (<em>g</em> = 0.168, 95 %CI: 0.046 to 0.3291) and help-seeking intentions (<em>g</em> = 0.135, 95 %CI: 0.072 to 0.198), as well as immediate mental health improvements (<em>g</em> = -0.074, 95 %CI: -0.115 to -0.033).</p></div><div><h3>Conclusion</h3><p>Overall, these findings underscore the promising effects of internet-based interventions in improving MHL and mental health, while maintaining these effects over time remains challenging, particularly in reducing stigma and promoting long-term help-seeking behaviors. Addressing methodological limitations, adopting a more interactive approach, and implementing targeted interventions are crucial to maximizing the effectiveness and advancing mental health care worldwide.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100489"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000541/pdfft?md5=71f8fe0c4e94a54eebbf7be0ea96a8bd&pid=1-s2.0-S1697260024000541-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141941197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Journal of Clinical and Health Psychology
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