Research in Social & Administrative Pharmacy最新文献

英文中文

Development and psychometric evaluation of knowledge, attitude, and behavior questionnaire on fall risk–increasing drugs (KABQ-FRID) 增加跌倒风险药物知识、态度和行为问卷（KABQ-FRID）的编制及心理测量学评价。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-07 DOI: 10.1016/j.sapharm.2025.08.013

Laksmi Maharani , Adi Yugatama , Dedik Sulistiawan , Shu-Chun Lee

Background

Fall risk–increasing drugs (FRIDs) increase the risks of falls, injuries, and fractures among older adults. However, limited evidence exists on how older adults perceive and manage FRID use, particularly in Indonesia.

Objective

This study developed and psychometrically evaluated a questionnaire for assessing knowledge, attitudes, and behaviors (KABs) related to FRID use (hereafter KABQ-FRID) among older adults.

Methods

KABQ-FRID was developed through a three-stage process. The first stage involved defining a conceptual framework and generating items based on a literature review, team discussions, and expert meeting. The second stage included an expert panel review and assessment of face validity. The third stage involved psychometric testing with 100 older adults receiving medications from a public health center in Surakarta City, Indonesia. Data analysis included Mokken scale analysis, confirmatory factor analysis (CFA), construct validity assessment, and reliability testing.

Results

The final KABQ-FRID comprised 21 items across 3 dimensions: knowledge (7 items), attitude (5 items), and behavior (9 items). Psychometric evaluation demonstrated acceptable scalability for all items (Loevinger's H ≥ 0.30) and strong reliability (Cronbach's α > 0.7; intraclass correlation coefficient >0.9). CFA results revealed a χ²/df of 2.0, suggesting a reasonable model fit; all dimensions exhibited satisfactory loadings. Construct validity testing demonstrated strong convergent validity; 90.5 % of the items had a correlation coefficient of >0.4, and 100 % of the items had stronger correlations within their dimensions than with other constructs.

Conclusion

KABQ-FRID is a reliable and valid instrument for assessing KAB related to FRID use among community-dwelling older adults.

背景：增加跌倒风险的药物（frid）会增加老年人跌倒、受伤和骨折的风险。然而，关于老年人如何看待和管理FRID使用的证据有限，特别是在印度尼西亚。目的：本研究编制了一份问卷，用于评估老年人与FRID使用（以下简称KABQ-FRID）相关的知识、态度和行为（kab），并对其进行心理测量学评估。方法：KABQ-FRID的研制分为三个阶段。第一阶段包括定义一个概念框架，并根据文献回顾、团队讨论和专家会议生成项目。第二阶段包括专家小组评审和人脸效度评估。第三阶段涉及对100名老年人进行心理测试，这些老年人从印度尼西亚苏拉arta市的一家公共卫生中心接受药物治疗。数据分析包括Mokken量表分析、验证性因子分析（CFA）、构念效度评估和信度检验。结果：最终的KABQ-FRID包括知识（7项）、态度（5项）和行为（9项）3个维度的21个项目。心理测量评估显示，所有项目的可扩展性均可接受（Loevinger's H≥0.30），可靠性强（Cronbach's α > 0.7；类内相关系数>0.9）。CFA结果显示χ2/df为2.0，表明模型拟合合理；所有尺寸均表现出令人满意的载荷。构念效度检验显示出较强的收敛效度；90.5%的题项的相关系数为bb0.5, 100%的题项在其维度内的相关系数高于与其他构念的相关系数。结论：KABQ-FRID是评估社区老年人与FRID使用相关的KAB的可靠和有效的工具。

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引用次数: 0

Pilot of a pharmacist-delivered habit-based intervention to support medication adherence in primary care 药剂师提供的以习惯为基础的干预试验，以支持初级保健中的药物依从性。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-06 DOI: 10.1016/j.sapharm.2025.09.003

Matthew Witry , James Hoehns , L. Alison Phillips

Purpose

Informed by the Extended Common Sense Model, this study aimed to pilot a pharmacist-led intervention to promote medication adherence through habit formation compared to standard education.

Procedures

Patients new to medication were recruited in two phases. During Phase 1, the pharmacist provided standard education (control). In Phase 2, the pharmacist added a habit-formation component by completing a habit worksheet with patients. Surveys measuring medication beliefs, habit strength, and adherence were completed at baseline and 100 days later. Cues from the habit worksheets were coded and analyzed.

Findings

The habit intervention group (N = 17) showed no significant difference from the control group (N = 16) in medication-taking habit strength (p = 0.37) or self-reported adherence (MARS-5) (p = 0.47) at follow-up. Habit strength was the only significant predictor of adherence (MARS-5)(p = 0.02), while necessity beliefs predicted missed doses (p = 0.03).

Conclusion

High levels of habit strength and adherence may result from high baseline adherence levels. Further research should target patients with known non-adherence or without established medication routines.

Clinical trial

# NCT06230978.

目的：根据扩展常识模型，本研究旨在试点药剂师主导的干预措施，与标准教育相比，通过养成习惯来促进药物依从性。程序：分两个阶段招募新用药患者。在第一阶段，药剂师提供标准教育（对照）。在第二阶段，药剂师通过与患者一起完成习惯工作表来增加习惯形成的成分。测量用药信念、习惯强度和依从性的调查在基线和100天后完成。习惯工作表中的提示被编码和分析。结果：随访时，习惯干预组（N = 17）与对照组（N = 16）在服药习惯强度（p = 0.37）、自我报告依从性（MARS-5）（p = 0.47）方面均无显著差异。习惯强度是依从性的唯一显著预测因子（MARS-5）（p = 0.02），而必要性信念预测错过剂量（p = 0.03）。结论：高水平的习惯强度和依从性可能源于高基线依从性水平。进一步的研究应针对已知的不依从性或没有既定药物常规的患者。临床试验：# NCT06230978。

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引用次数: 0

Contributing factors of pediatric medication errors involving high-alert medications: A qualitative content analysis of self-reported medication safety incidents 涉及高警惕性药物的儿科用药差错的影响因素：自我报告用药安全事件的定性内容分析

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-05 DOI: 10.1016/j.sapharm.2025.09.002

Sini Kuitunen , Mari Saksa , Anna-Riia Holmström

Background

High-alert medications can cause severe medication errors (MEs) in pediatrics. A comprehensive understanding of the factors contributing to errors is needed to establish risk management actions.

Objective

To analyze incident reports involving high-alert medications and describe the contributing factors (CFs) of MEs in pediatrics.

Methods

A retrospective document analysis study utilizing an abductive qualitative content analysis of self-reported medication safety incidents concerning high-alert medications at a pediatric university hospital from 2018 to 2020. Incident reports (n = 426) were first subjected to an inductive qualitative content analysis to identify and categorize CFs, then quantified by frequencies and percentages, and ultimately deductively categorized based on the elements of the Systems Engineering Initiative for Patient Safety (SEIPS) model. The analysis was first conducted by one independent researcher, then reviewed by a second researcher, and later reviewed by the entire research group.

Results

A total of 933 CFs were identified, concerning 85.0 % (n = 362/426) of the incident reports. The most common main categories of CFs pertained to verifying the correct drug (11.1 %; n = 104/933), medications and pharmaceuticals (10.6 %; n = 99/933), and resourcing (10.5 %; n = 98/933). Over half of the CFs were linked to SEIPS elements involving tasks (39.6 %, n = 370) and tools and technologies (20.8 %, n = 194).

Conclusions

The CFs of pediatric MEs involving high-alert medications are multifaceted and have a wide impact on the entire system design, from organizational strategies to individual tasks. Risk management actions and further studies addressing pediatric-specific challenges are required to ensure the most optimal systemic defenses, enabling proactive monitoring error-provoking conditions in clinical practice.

背景：高警惕性药物可导致儿科严重用药错误（MEs）。建立风险管理行动需要全面了解导致错误的因素。目的：分析涉及高危药物的儿科MEs事件报告，并描述其影响因素（CFs）。方法：采用回溯性文献分析方法，对某儿科大学附属医院2018 - 2020年高危药物自述用药安全事件进行定性内容分析。事件报告（n = 426）首先进行归纳定性内容分析，以识别和分类CFs，然后根据频率和百分比进行量化，最终根据患者安全系统工程倡议（SEIPS）模型的要素进行演绎分类。该分析首先由一名独立研究人员进行，然后由另一名研究人员进行审查，后来由整个研究小组进行审查。结果：共发现CFs 933例，占事件报告的85.0% （n = 362/426）。最常见的CFs主要类别与验证正确的药物（11.1%,n = 104/933）、药物和药品（10.6%,n = 99/933）和资源（10.5%,n = 98/933）有关。超过一半的cf与涉及任务（39.6%,n = 370）和工具和技术（20.8%,n = 194）的SEIPS要素相关。结论：涉及高警惕性药物的儿科MEs的CFs是多方面的，对整个系统设计具有广泛的影响，从组织策略到个人任务。风险管理行动和针对儿科特定挑战的进一步研究需要确保最优的系统防御，从而在临床实践中主动监测引起错误的条件。

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Health Belief Profiles and Nonadherence to Oral Anticancer Medication in Cancer Survivors: A Latent Profile Analysis 癌症幸存者的健康信念谱和口服抗癌药物不依从性：一项潜在谱分析

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Pharmacotherapy Optimisation for Nursing Home Residents: A Multidisciplinary Team Approach 护理之家居民的药物治疗优化：多学科团队方法

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Pharmacist action at the pharmacy checkpoint before safe drug dispensation to older people 药师在给老年人安全配药前在药房检查站的行动

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Expanding pharmacist role in the management of opioid use disorder through extended-release buprenorphine administration, a qualitative analysis 通过丁丙诺啡缓释管理扩大药师在阿片类药物使用障碍管理中的作用，一项定性分析

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Strengthening multidisciplinary approaches against antimicrobial resistance: A collaborative initiative reflecting on science, policy, regulatory and clinical practices 加强抗微生物药物耐药性的多学科方法：一项反映科学、政策、监管和临床实践的合作倡议

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