Research in Social & Administrative Pharmacy最新文献_第7页

PharmaCenter: Impact of post-discharge pharmaceutical carea consultation on medication-related problems in the emergenc department: A comprehensive analysis 药师：出院后药学服务会诊对急诊科用药相关问题的影响——综合分析

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-22 DOI: 10.1016/j.sapharm.2025.10.010

Beatriz Torroba-Sanz , Ana De Lorenzo-Pinto , Álvaro Giménez-Manzorro , Carmen Redondo-Galán , Daniel Gómez-Costas , Juana Benedí , Ana Herranz-Alonso , Maria Sanjurjo-Sáez

Background

Transitions of care, particularly after discharge from hospital emergency services, are critical periods associated with a high risk of medication-related problems. These often arise from communication failures and incomplete pharmacotherapeutic information. PharmaCenter was established as a pharmacist-led consultation service designed to manage pharmacotherapeutic queries arising after hospital discharge.

Objective

To describe the implementation of PharmaCenter and evaluate its clinical performance. Secondary objectives included assessing its capacity to resolve medication-related problems, analyzing service accessibility and usability, and evaluating patient satisfaction.

Methods

A retrospective observational study was conducted over two years in a tertiary teaching hospital. The service was available 24 h a day, seven days a week, providing patients discharged from three emergency departments with access to consultation by telephone or email. Each query was analyzed in terms of origin, time to consultation, time to resolution, and need for physician involvement. A structured survey was used to assess patient satisfaction.

Results

Over the study period, 1485 patients used the service, generating 1626 consultations. Most queries originated from adult emergency care. The median time from discharge to consultation was 2.33 days, and the mean resolution time was 1.36 h. In 54.1 percent of cases, pharmacists provided a complete response without physician input. The most frequent issue was failure to prescribe medications in the electronic prescribing system. Among respondents to the satisfaction survey, 93.9 percent indicated the service helped avoid a return to a healthcare facility.

Conclusions

PharmaCenter effectively addressed post-discharge medication-related problems and demonstrated high levels of patient satisfaction, offering a scalable model to support safer transitions of care.

背景：护理过渡期，特别是从医院急诊服务出院后，是与药物相关问题高风险相关的关键时期。这通常是由于沟通失败和药物治疗信息不完整造成的。PharmaCenter是一个药剂师主导的咨询服务，旨在管理出院后产生的药物治疗问题。目的：介绍药学中心的实施情况，评价其临床效果。次要目标包括评估其解决药物相关问题的能力，分析服务的可及性和可用性，以及评估患者满意度。方法：在某三级教学医院进行为期两年的回顾性观察研究。该服务每周7天、每天24小时提供，为从三个急诊科出院的病人提供电话或电子邮件咨询服务。分析每个查询的来源、咨询时间、解决时间和医生参与的需要。采用结构化调查来评估患者满意度。结果：在研究期间，1485名患者使用了这项服务，产生了1626次咨询。大多数查询来自成人急诊护理。从出院到会诊的中位时间为2.33天，平均解决时间为1.36小时。在54.1%的病例中，药剂师在没有医生输入的情况下提供了完整的响应。最常见的问题是未能在电子处方系统中开药。在满意度调查的受访者中，93.9%的人表示，这项服务有助于避免再次回到医疗机构。结论：PharmaCenter有效地解决了出院后药物相关问题，并展示了高水平的患者满意度，提供了一个可扩展的模型来支持更安全的护理过渡。

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引用次数: 0

Impact of pharmacist-led interventions on economic, clinical, and humanistic outcomes (ECHO) in patients admitted to emergency departments: A systematic review of randomized controlled trials 药剂师主导的干预措施对急诊科入院患者的经济、临床和人文预后（ECHO）的影响：随机对照试验的系统综述

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-21 DOI: 10.1016/j.sapharm.2025.10.007

Emre Kara , Betul Okuyan , Cansu Goncuoglu , Kutay Demirkan , Shusen Sun

Background

The role of pharmacists in emergency departments (EDs) has undergone a significant transformation globally, expanding beyond traditional responsibilities to include various clinical activities that promise to enhance patient outcomes. However, the full potential of these interventions, particularly from economic, clinical, and humanistic (ECHO) perspectives, remains to be systematically explored. The aim of this study was to evaluate the impact of pharmacist-led interventions on ECHO among patients admitted to the ED.

Methods

This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Searches were conducted in PubMed, MEDLINE, and International Pharmaceutical Abstracts, focusing on randomized controlled trials (RCTs) published in English that involved pharmacist interventions in EDs. Data were extracted on study design, pharmacist interventions, and patient outcomes. Cochrane risk-of-bias tool for randomized trials (RoB 2.0) was used.

Results

Twelve RCTs that met the inclusion criteria were identified. The studies were conducted predominantly in tertiary care settings in various countries. The most common interventions performed by pharmacists included medication reconciliation, obtaining medication histories, and patient education. The review showed that pharmacist interventions tend to improve medication safety and patient satisfaction but varied significantly in their execution and reported outcomes. No studies comprehensively analyzed economic outcomes, and only a few addressed humanistic outcomes.

Conclusions

Pharmacy-led services improved clinical outcomes, however there was lack of studies showing the economic and humanistic outcomes of these services. The need for standardized protocols and further research to establish their broader impacts should be considered. The findings support the continued integration and expansion of pharmacist roles in emergency care, which could influence global policy and practice in healthcare systems.

在全球范围内，急诊科（ed）药剂师的角色经历了重大转变，超越了传统的职责，包括各种有望提高患者预后的临床活动。然而，这些干预措施的全部潜力，特别是从经济、临床和人文（ECHO）的角度来看，仍有待系统地探索。本研究的目的是评估药剂师主导的干预措施对ed住院患者的ECHO的影响。方法本系统评价按照系统评价和荟萃分析（PRISMA）指南的首选报告项目进行。我们在PubMed、MEDLINE和国际药学文摘中进行了检索，重点是随机对照试验（RCTs），这些试验用英文发表，涉及药剂师对急诊科的干预。我们提取了研究设计、药剂师干预和患者预后方面的数据。采用Cochrane随机试验风险偏倚工具（RoB 2.0）。结果共纳入12项符合纳入标准的随机对照试验。这些研究主要是在各国的三级保健机构进行的。药剂师最常见的干预措施包括药物和解、获取用药史和患者教育。回顾显示，药师干预倾向于提高用药安全性和患者满意度，但在执行和报告结果方面差异显着。没有研究全面分析经济成果，只有少数研究涉及人文成果。结论以药房为主导的服务改善了临床结果，但缺乏研究显示这些服务的经济和人文效果。应考虑是否需要标准化的协议和进一步研究以确定其更广泛的影响。研究结果支持药剂师在急诊护理中的持续整合和扩大作用，这可能影响全球卫生保健系统的政策和实践。

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引用次数: 0

Evaluation of the Aged Care On-site Pharmacist (ACOP) program in Australian residential aged care homes: Key considerations and next steps 澳大利亚老年护理院老年护理现场药剂师（ACOP）计划的评估：关键考虑因素和下一步

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-14 DOI: 10.1016/j.sapharm.2025.10.006

Janet K. Sluggett , Daria S. Gutteridge , Annabel Calder , Georgina A. Hughes , Elizabeth Manias , Shanthi A. Ramanathan , Kurtis Budden , Ingrid Sketris , Sara Javanparast

Older people who live in residential aged care homes (RACHs) often experience polypharmacy and use potentially inappropriate medications. In response to issues identified by a recent national inquiry that identified the need to improve medication management practices in Australian RACHs, a federal government-subsidized initiative to enable clinical pharmacists to practice on-site in Australian RACHs has recently been launched. This new optional program has been funded to enhance quality use of medicines and resident's health and wellbeing in Australian RACHs. This commentary discusses the need for a comprehensive evaluation of this population-based and publicly subsidized initiative to improve medication management in RACHs. It presents a program logic model that outlines the required activities, key outputs and anticipated impacts of Australia's RACH on-site pharmacist program to aid program implementers and beneficiaries to plan, communicate, and evaluate this new program. The program logic model presented can also inform the actions of policy makers and program implementers in other countries who are involved in planning, execution and evaluation of new pharmacist-led interventions or programs in RACHs.

居住在养老院（RACHs）的老年人经常使用多种药物，并可能使用不适当的药物。最近，一项全国性的调查发现，需要改善澳大利亚乡村医院的药物管理实践，为了应对这一问题，联邦政府资助了一项倡议，使临床药剂师能够在澳大利亚乡村医院现场执业。这项新的可选方案已获得资助，以提高澳大利亚地区药品的使用质量和居民的健康和福祉。本评论讨论了对这一以人群为基础的公共补贴倡议进行全面评估的必要性，以改善乡村地区的药物管理。它提出了一个项目逻辑模型，概述了澳大利亚RACH现场药剂师项目所需的活动、主要产出和预期影响，以帮助项目实施者和受益者计划、沟通和评估这个新项目。所提出的项目逻辑模型也可以为其他国家的政策制定者和项目实施者的行动提供参考，这些国家和地区的政策制定者和项目实施者参与了新药剂师主导的干预措施或项目的规划、执行和评估。

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引用次数: 0

Professional autonomy in pharmacists: Independence within interdependence 药师的职业自主：相互依存中的独立。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-13 DOI: 10.1016/j.sapharm.2025.10.005

Paul Forsyth , Jessica Baker , Willa Saadat , Andrew Radley

As the duties of pharmacists evolve it can be difficult for many to foster and maintain professional autonomy within both new and core roles. However, it is important for us to understand what autonomy actually means. Autonomy is a common word in every-day use describing a philosophical concept concerning an agent's capacity for self-determination. Professional standards typically try to ensure the required level of individual professional autonomy necessary for pharmacists to deliver care in the best interests of patients. Professional autonomy is a key factor in achieving job satisfaction, meaningful work, and flourishing in a professional role, and when inhibited can lead to negative career experiences and outcomes. Autonomy can however be understood both in this individual sense, linked to liberty and independence, but also in a collective sense, linked to relationships and societal empowerment. This paper examines how pharmacists have understood these differing conceptual views of professional autonomy to date, describing the theoretical basis for each, and then sketching a series of short scenarios that illustrate how the professional autonomy of individual pharmacists can be heavily influenced by many interdependent factors, including relational factors, employment factors, professional factors, and societal factors. Finally, the paper considers the principles and skills needed for pharmacists to create a more stable professional autonomy, both individually and collectively.

随着药剂师职责的演变，对于许多人来说，在新的和核心的角色中培养和保持专业自主权是很困难的。然而，理解自治的真正含义对我们来说很重要。自治是一个日常使用的常见词汇，描述了一个关于主体自决能力的哲学概念。专业标准通常试图确保药剂师为患者提供最佳利益所必需的个人专业自主水平。职业自主是获得工作满意度、有意义的工作和在职业角色中蓬勃发展的关键因素，当被抑制时，可能会导致负面的职业经历和结果。然而，自治既可以从与自由和独立相关的个人意义上理解，也可以从与关系和社会赋权相关的集体意义上理解。本文考察了迄今为止药剂师如何理解这些不同的专业自主概念观点，描述了每种观点的理论基础，然后勾勒出一系列简短的场景，说明药师个人的专业自主如何受到许多相互依存的因素的严重影响，包括关系因素、就业因素、专业因素和社会因素。最后，本文考虑了药剂师创造更稳定的专业自主权所需的原则和技能，无论是个人还是集体。

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引用次数: 0

Enabling real-world community pharmacy research: A realist review of practice-based research networks (PBRNs) 实现现实世界社区药学研究：基于实践的研究网络（pbrn）的现实主义回顾。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-13 DOI: 10.1016/j.sapharm.2025.10.004

Louisa Handyside , Jacqui Cameron , Christopher Freeman

Background

Engaging pharmacists in research and bridging the research-practice divide is a persistent challenge. Practice-based research networks aim to support research engagement, overcome research barriers, and generate evidence to advance practice. However, the outcomes of existing networks remain unexplored. Thus, the objectives of this realist review are: 1) to develop and refine a realist program theory to explain how and why these networks support research engagement and knowledge translation, for whom and in what contexts and 2) to provide preliminary recommendations to optimise network outcomes.

Methods

An initial program theory was developed, followed by an iterative process of formal and complementary searching. Data was selected, appraised, extracted, organised, and synthesised using a realist approach to refine the program theory.

Results

The refined program theory consisted of 12 context-mechanism-outcome configurations that explain the two key drivers of network success: 1) mutual benefits for a diverse range of actively engaged researchers and pharmacists, and 2) sustainable resourcing and maintenance of strategic collaborative partnerships. Stakeholder recommendations are underpinned by the modifiable contexts and resources that underscore optimal network outcomes.

Conclusion

A realist program theory was developed to explain how research networks may be used to bridge the divide between research and community pharmacy practice. The theory explains the causal processes underpinning successful outcomes and informs preliminary recommendations for network development, implementation, and maintenance. The review provides a robust foundation to explain how networks can optimise community pharmacy research. Futher research is warranted to confirm their translational potential.

背景：从事研究和弥合研究与实践的鸿沟药剂师是一个持久的挑战。基于实践的研究网络旨在支持研究参与，克服研究障碍，并产生证据以推进实践。然而，现有网络的结果仍未得到探索。因此，本现实主义回顾的目标是：1)发展和完善现实主义计划理论，以解释这些网络如何以及为什么支持研究参与和知识翻译，为谁以及在什么背景下支持；2)提供初步建议以优化网络结果。方法：建立了一个初步的程序理论，然后进行了形式和互补搜索的迭代过程。数据的选择，评估，提取，组织和综合使用现实主义的方法来完善程序理论。结果：完善的项目理论由12个情境-机制-结果配置组成，这些配置解释了网络成功的两个关键驱动因素：1)各种积极参与的研究人员和药剂师的互利；2)战略合作伙伴关系的可持续资源和维护。利益相关者的建议以可修改的环境和资源为基础，强调最佳的网络结果。结论：现实主义计划理论的发展是为了解释研究网络如何被用来弥合研究和社区药房实践之间的鸿沟。该理论解释了支撑成功结果的因果过程，并为网络开发、实施和维护提供了初步建议。该综述为解释网络如何优化社区药学研究提供了坚实的基础。需要进一步的研究来证实它们的转化潜力。

{"title":"Enabling real-world community pharmacy research: A realist review of practice-based research networks (PBRNs)","authors":"Louisa Handyside , Jacqui Cameron , Christopher Freeman","doi":"10.1016/j.sapharm.2025.10.004","DOIUrl":"10.1016/j.sapharm.2025.10.004","url":null,"abstract":"<div><h3>Background</h3><div>Engaging pharmacists in research and bridging the research-practice divide is a persistent challenge. Practice-based research networks aim to support research engagement, overcome research barriers, and generate evidence to advance practice. However, the outcomes of existing networks remain unexplored. Thus, the objectives of this realist review are: 1) to develop and refine a realist program theory to explain how and why these networks support research engagement and knowledge translation, for whom and in what contexts and 2) to provide preliminary recommendations to optimise network outcomes.</div></div><div><h3>Methods</h3><div>An initial program theory was developed, followed by an iterative process of formal and complementary searching. Data was selected, appraised, extracted, organised, and synthesised using a realist approach to refine the program theory.</div></div><div><h3>Results</h3><div>The refined program theory consisted of 12 context-mechanism-outcome configurations that explain the two key drivers of network success: 1) mutual benefits for a diverse range of actively engaged researchers and pharmacists, and 2) sustainable resourcing and maintenance of strategic collaborative partnerships. Stakeholder recommendations are underpinned by the modifiable contexts and resources that underscore optimal network outcomes.</div></div><div><h3>Conclusion</h3><div>A realist program theory was developed to explain how research networks may be used to bridge the divide between research and community pharmacy practice. The theory explains the causal processes underpinning successful outcomes and informs preliminary recommendations for network development, implementation, and maintenance. The review provides a robust foundation to explain how networks can optimise community pharmacy research. Futher research is warranted to confirm their translational potential.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 209-221"},"PeriodicalIF":2.8,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacists on the frontline: Medication misuse and abuse during violent conflict in four MENA countries 一线药剂师：四个中东和北非国家暴力冲突期间药物误用和滥用。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-11 DOI: 10.1016/j.sapharm.2025.10.003

Mayyada Wazaify , Christina Steenkamp , Haya Yasin

Purpose

An important, yet under-researched, impact of violent conflict on public health is the susceptibility of populations in conflicts to drug abuse and misuse as increased stress, the easy availability of drugs, and the relaxation of taboos against drug use exacerbate the problem. This study explores the experiences of pharmacists regarding drug misuse and abuse in four conflict-affected MENA countries.

Methods

The study is part of a larger two-year (2021–2023) project investigating the impact of violent conflict in the MENA region on medicine abuse and misuse and the experiences of pharmacists in managing this challenge. This part used a quantitative approach using survey methodology with a sample of pharmacists in Syria, Libya, Yemen and Iraq.

Results

A total of 181 questionnaires were filled (65.7 % male, mean age = 29.9 years old. The majority of the pharmacists (n = 170, 93.9 %) reported that on average, 27.88 % of the pharmacy customers were suspected of misusing/abusing medications in the past 3 months. The most misused medicines were pregabalin and sedatives/hypnotics followed by opioids like tramadol, in addition to cough and cold and anti-allergy preparations. Almost one-third of respondents (31.49 %) refused to dispense drugs which they thought were intended to be used inappropriately. Sixty-five (35.9 %) said that they had been subjected to violence for the sake of obtaining medications, and 17 (9.8 %) reported being threatened five times or more in the past year.

Conclusion

Based on the results above, future interventions in conflict settings must address both supply-side governance and the broader psychosocial drivers of medication misuse/abuse to ensure that pharmacists are supported rather than exposed in their essential work.

目的：暴力冲突对公共健康的一个重要但尚未得到充分研究的影响是，冲突中的人口容易受到药物滥用和误用的影响，因为压力的增加、药物的容易获得以及对药物使用禁忌的放松加剧了这一问题。本研究探讨了四个受冲突影响的中东和北非国家的药剂师在药物滥用和滥用方面的经验。方法：该研究是一个为期两年（2021-2023）的大型项目的一部分，该项目旨在调查中东和北非地区暴力冲突对药物滥用和误用的影响以及药剂师应对这一挑战的经验。本部分采用定量方法，对叙利亚、利比亚、也门和伊拉克的药剂师进行抽样调查。结果：共收集问卷181份，男性占65.7%，平均年龄29.9岁。大部分受访药师（170名，93.9%）表示，在过去3个月内，平均有27.88%的受访药师曾怀疑误用/滥用药品。滥用最多的药物是普瑞巴林和镇静剂/催眠药，其次是曲马多等阿片类药物，此外还有止咳、感冒药和抗过敏制剂。几乎三分之一的受访者（31.49%）拒绝配发他们认为意图不当使用的药物。65人（35.9%）表示，他们曾因获取药物而遭受暴力，17人（9.8%）报告在过去一年中受到五次或更多次威胁。结论：基于上述结果，未来在冲突环境中的干预措施必须解决供应方治理和药物误用/滥用的更广泛的社会心理驱动因素，以确保药剂师得到支持，而不是暴露在他们的基本工作中。

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引用次数: 0

Comparison of pharmacist-led medication reconciliation and usual care on detecting and resolving discrepancies in major orthopaedic surgeries: A quasi-experimental study 药师主导的药物调解与常规护理在重大骨科手术中发现和解决差异的比较：一项准实验研究。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-10 DOI: 10.1016/j.sapharm.2025.10.001

Karen R. Palermo , Jesús Cotrina Luque , Natália Marto , Miriam Capoulas , Cláudia Santos , Isabel V. Figueiredo , Margarida Castel-Branco

Background

Medication reconciliation can reduce errors, particularly among elderly and polymedicated patients. The inclusion of pharmacists obtaining the best possible medication history can further improve the identification and resolution of discrepancies.

Aim

To compare a structured pharmacist-led medication reconciliation program with usual care on detecting and resolving discrepancies during hospital admission for major orthopaedic surgeries.

Methods

Quasi-experimental study, conducted in a Portuguese tertiary hospital, involving adult patients undergoing major orthopaedic surgery and taking chronic medication. In Phase One (usual care), reconciliation lacked standardization; pharmacists performed it alongside other tasks, relying solely on medical records and reported unintentional discrepancies electronically to prescribers. In Phase Two (pharmacist-led medication reconciliation), a designated pharmacist obtained the best possible medication history, identified discrepancies and communicated them directly to clinical pharmacologists. Validated high-risk criteria were used to assess clinical significance. Primary outcomes were identifying, classifying, and resolving unintentional discrepancies across both phases.

Results

The study included 182 patients (91 in each phase). In Phase One, 212 discrepancies were identified, 91 were unintentional, of which 30 had clinical significance. Ten pharmacist interventions were performed, with 50 % acceptance rate. In Phase Two, 339 discrepancies were identified, 129 were unintentional, of which 46 had clinical significance. A total of 104 pharmacist interventions were performed, with 73 % acceptance rate. Identification and resolution of unintentional discrepancies significantly increased (p < 0.001).

Conclusion

Pharmacist-led medication reconciliation, focusing on the best possible medication history collection and direct contact with physicians, significantly increased the identification and resolution of discrepancies, underlining its role in enhancing patient safety.

背景：药物和解可以减少错误，特别是在老年人和多药患者。纳入获得最佳用药史的药剂师可以进一步改善差异的识别和解决。目的：比较结构化药剂师主导的药物和解方案与常规护理在发现和解决重大骨科手术住院期间的差异方面的差异。方法：准实验研究，在葡萄牙某三级医院进行，涉及接受骨科大手术并长期服药的成年患者。在第一阶段（常规护理），和解缺乏标准化；药剂师在执行其他任务的同时，也只依靠医疗记录，并以电子方式向处方医生报告无意的差异。在第二阶段（药剂师主导的药物调解），指定的药剂师获得尽可能最好的用药史，识别差异并直接与临床药理学家沟通。采用经过验证的高危标准评估临床意义。主要结果是识别、分类和解决两个阶段的非故意差异。结果：研究纳入182例患者（每期91例）。在第一阶段，发现212个差异，91个是无意的，其中30个具有临床意义。进行10次药师干预，接受率为50%。在第二阶段，发现了339个差异，129个是无意的，其中46个具有临床意义。共实施药师干预104次，接受率为73%。结论：药师主导的药物调解，注重尽可能收集最佳用药史和与医生直接联系，显著增加了对差异的识别和解决，强调了其在提高患者安全方面的作用。

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引用次数: 0

A digital health-supported community pharmacy-based lifestyle intervention program for overweight or obese adults with prediabetes, the PRediabetes Intervention, Management and Evaluation (PRIME) Program: A cluster randomized controlled trial 糖尿病前期干预、管理和评估（PRIME）项目：一项针对超重或肥胖糖尿病前期成人的数字健康支持社区药房生活方式干预项目：一项随机对照试验。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-06 DOI: 10.1016/j.sapharm.2025.10.002

Kah Woon Teoh , Choon Ming Ng , Chun Wie Chong , Yi Ling Ng , J Simon Bell , Shaun Wen Huey Lee

Background

Evidence on the impact of using digital health tools to facilitate prediabetes management in community pharmacies is lacking. This study aimed to evaluate the effects of a digital health-supported and community pharmacy-based lifestyle intervention (PRIME) program on individuals with prediabetes in Malaysia.

Methods

A two-arm cluster randomised controlled trial was conducted in 16 community pharmacies from two states in Malaysia and included people with prediabetes that were overweight or obese. The intervention group received support of in-depth counselling from pharmacists, in-app prediabetes education modules, and peer support, while the usual care group received counselling based on pharmacists’ usual practice. The primary outcomes were the proportion of participants achieving ≥5 % weight loss and differential change in weight. All analyses were performed using intention to treat analyses with mixed effect modelling.

Findings

Ninety-one participants (intervention, n = 46; usual care n = 45) were recruited. At the end of study, participants in the intervention group were twice as likely compared to the usual care group to report a minimum 5 % weight loss (21 % intervention and 7.5 % usual care participants, odds ratio: 2.5, p = 0.266). Intervention group participants also reported a larger weight loss, with a mean difference of 1.26 kg (95 %CI -2.36 kg to −0.15 kg) between groups. These differences were more significant especially among those who were more engaged with PRIME.

Conclusion

The intervention showed greater weight loss than the usual care, but the proportion of individuals achieving clinically meaningful weight loss (≥5 %) was not significant. PRIME program can be an important and useful tool to improve risk factors among individuals with prediabetes especially in a low-resource setting. Further research is needed to determine the economic and long-term sustainability of such programs.

背景：缺乏关于使用数字健康工具促进社区药房糖尿病前期管理的影响的证据。本研究旨在评估马来西亚数字健康支持和基于社区药房的生活方式干预（PRIME）计划对前驱糖尿病患者的影响。方法：在马来西亚两个州的16个社区药房进行了一项双组随机对照试验，其中包括超重或肥胖的前驱糖尿病患者。干预组以药师深度咨询、app内糖尿病前期教育模块、同伴支持为支持，常规护理组以药师惯例为支持。主要结局是体重减轻≥5%的参与者比例和体重差异变化。所有分析均采用混合效应模型进行意向处理分析。结果：招募了91名参与者（干预组，n = 46；常规组，n = 45）。在研究结束时，干预组的参与者报告体重减轻至少5%的可能性是常规护理组的两倍（21%的干预和7.5%的常规护理参与者，优势比：2.5,p = 0.266）。干预组的参与者也报告了更大的体重减轻，组间平均差异为1.26 kg （95% CI -2.36 kg至-0.15 kg）。这些差异更显著，尤其是那些更参与PRIME的人。结论：与常规护理相比，干预显示出更大的体重减轻，但达到临床有意义的体重减轻（≥5%）的个体比例并不显著。PRIME计划可以成为改善糖尿病前期个体风险因素的重要而有用的工具，特别是在资源匮乏的环境中。需要进一步的研究来确定这些项目的经济和长期可持续性。

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引用次数: 0

Exploring the concept and definition of scope of practice in pharmacy: A scoping review 探索药学实践范围的概念和定义：范围综述。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-10-03 DOI: 10.1016/j.sapharm.2025.09.007

Mitchell Budden , Shalom I. Benrimoj , Francisco Martinez Mardones , Sarah Dineen-Griffin

Background

The term scope of practice (SOP) is gaining increasing traction within the pharmacy profession, reflecting its growing importance. Despite this, definitions and interpretations remain varied, as evidenced by the number of definitions and the variety of synonyms and adjectives used in the literature.

Objectives

(i) To examine the conceptual diversity in terminology used to describe SOP for the pharmacy profession across different jurisdictions; (ii) to propose a curated list of definitions and examples, along with recommended contexts for their application at local, national, and international levels.

Methods

A scoping review was conducted following JBI methodology and reported according to PRISMA-ScR guidelines. PubMed, Scopus, Web of Science, and Embase were searched to January 2025. Grey literature was explored using Google, the Overton database, and other methods. Titles and abstracts of identified records were screened, followed by full-text review against inclusion criteria. Definitions were systematically categorised to identify thematic patterns, overlaps, and distinctions, informing the development of a curated list of SOP definitions for pharmacy.

Results

Of 4,010 peer-reviewed records, 2,106 were screened after removing duplicates, with 31 publications meeting inclusion criteria. An additional 49 grey literature reports were included. A total of 172 definitions were compiled, capturing both phrasing and contextual application of SOP terminology. While no single universally accepted definition emerged, most aligned with three dominant conceptual themes.

Conclusions

The growing focus on pharmacy SOP highlights the need for a more unified and strategic framework. Consolidating definitions into a curated and accessible resource can improve clarity and consistency across educational, clinical, policy, and regulatory domains.

背景：术语实践范围（SOP）在药学专业中越来越受到关注，反映了其日益增长的重要性。尽管如此，定义和解释仍然各不相同，这可以从文学中定义的数量和同义词和形容词的多样性中得到证明。目的：(i)检查不同司法管辖区用于描述药学专业SOP的术语的概念多样性；（ii）提出一份定义和例子的精选清单，以及在地方、国家和国际层面应用这些定义和例子的推荐背景。方法：根据JBI方法进行范围审查，并根据PRISMA-ScR指南进行报告。PubMed, Scopus， Web of Science和Embase被检索到2025年1月。使用谷歌、Overton数据库和其他方法对灰色文献进行了探索。筛选已确定记录的标题和摘要，然后根据纳入标准对全文进行审查。定义被系统地分类，以确定主题模式、重叠和区别，为制定药理学SOP定义的策划清单提供信息。结果：在4010篇同行评议的文献中，剔除重复文献后筛选了2106篇，其中31篇符合纳入标准。另外纳入49份灰色文献报告。总共编制了172个定义，捕获了SOP术语的措辞和上下文应用。虽然没有一个被普遍接受的定义出现，但大多数定义与三个主要概念主题一致。结论：药房SOP越来越受到重视，需要一个更加统一和战略性的框架。将定义整合到一个管理的和可访问的资源中，可以提高跨教育、临床、政策和监管领域的清晰度和一致性。

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引用次数: 0

Collaborative pharmacist prescribing models in Australian hospitals: A scoping study 澳大利亚医院的协作药剂师处方模式：一项范围研究。

IF 2.8 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Research in Social & Administrative Pharmacy

Pub Date : 2025-09-27 DOI: 10.1016/j.sapharm.2025.09.006

Hana Amer , Sally Marotti , Imaina Widagdo , Sharon Goldsworthy , Jacinta Johnson , Lisa Kalisch Ellett

Background

Collaborative pharmacist prescribing models have been trialled and implemented in Australian hospitals and involve credentialed pharmacists working with doctors and patients to develop patient medicine plans and prescribe medicines.

Aim

This study aimed to identify pharmacist prescribing policies and procedures in Australian hospitals and provide a narrative summary of the models and associated training.

Method

A scoping study was conducted using an exploratory and descriptive approach to identify and map pharmacist prescribing models implemented in Australian hospitals, and their associated training. Hospital pharmacy directors in Australia were contacted through a hospital pharmacy professional organisation in November 2023 and were asked to provide their pharmacist prescribing policies and procedures. Details of the models and training programs were extracted and summarised, with similarities and differences narratively reported.

Results

Fifteen different collaborative pharmacist prescribing models were reported to be implemented across more than 35 hospitals. Fourteen models had a formal training program. The models varied in scope of practice, particularly relating to medicine initiation and the timing of prescribing. The training and maintenance of currency of practice differed between models. Only three models recognised credentialing from other hospitals.

Conclusion

The study reveals variation in scope of practice, training, and credentialing processes between pharmacist prescribing models, with limited recognition and transferability of prescribing skills across jurisdictions in Australia. Efforts to establish national accreditation standards for pharmacist prescriber education programs and the recent introduction of a national credentialing program, could pave the way for the standardisation of the models and training within Australian hospitals.

背景：协作药剂师处方模式已在澳大利亚医院试行和实施，涉及有资格的药剂师与医生和患者合作制定患者用药计划和开药。目的：本研究旨在确定澳大利亚医院的药剂师处方政策和程序，并提供模型和相关培训的叙述性总结。方法：采用探索性和描述性方法进行范围研究，以确定和绘制澳大利亚医院实施的药剂师处方模型及其相关培训。2023年11月，通过一家医院药房专业组织联系了澳大利亚的医院药房主任，并要求他们提供药剂师开处方的政策和程序。对模型和训练方案的细节进行了提取和总结，并叙述了异同。结果：据报道，在超过35家医院实施了15种不同的协作药剂师处方模式。14名模特接受了正式的培训。这些模式在实践范围上各不相同，特别是与药物起始和处方时间有关。不同的模型对实践货币的培训和维护是不同的。只有三个模型承认其他医院的证书。结论：该研究揭示了药剂师处方模式之间的实践范围、培训和资格认证过程的差异，以及澳大利亚各司法管辖区对处方技能的有限认可和可转移性。为药剂师开处方者教育项目建立国家认证标准的努力，以及最近引入的国家资格认证项目，可以为澳大利亚医院内模式和培训的标准化铺平道路。

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引用次数: 0