首页 > 最新文献

Research in Social & Administrative Pharmacy最新文献

英文 中文
Pharmacy technicians in Europe: exploring the diversity in training, roles, and regulation. 欧洲的药学技术人员:探索培训、角色和监管的多样性。
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-04 DOI: 10.1016/j.sapharm.2025.12.001
Carolina Valeiro, Vitor Silva, Ângelo Jesus, João Joaquim, Cristiano Matos

Background: Pharmacy technicians are increasingly recognized as essential healthcare professionals who contribute significantly to the delivery of pharmacy services. However, in Europe, the education, training, and regulatory frameworks governing pharmacy technicians vary substantially, influencing their scope of practice and integration within healthcare systems.

Objective: This review maps the education, qualifications, and scope of practice of PTs across Europe, highlighting differences in professional titles and regulatory approaches.

Methods: A review was conducted using publicly available data from the EU Regulated Professions Database and data collected from national organizations representing pharmacy technicians across Europe. Data on professional titles, qualification levels, regulations, program duration, and role delineation were extracted and summarized for comparison.

Results: Findings from 28 European countries revealed significant variability in pharmacy technician qualification levels (EQF 4-6), training duration (2-4.5 years), and national regulation. Regulation ranges from mandatory licensing with protected titles to a lack of regulation. The scope of practice differs, from basic dispensing and inventory tasks to broader clinical and technical responsibilities.

Conclusion: The landscape of pharmacy technician education and regulation in Europe remains fragmented. Although PTs share core responsibilities, qualification levels, program durations, and regulatory protections vary widely, limiting professional identity, mobility, and workforce planning. Developing a shared European framework for education and professional recognition could facilitate professional mobility, reduce professional and skill disparities, and support safe, high-quality pharmacy services, ultimately optimizing the contribution of PTs to healthcare systems.

背景:药学技术人员越来越被认为是重要的医疗保健专业人员,他们对药学服务的提供做出了重大贡献。然而,在欧洲,管理药学技术人员的教育、培训和监管框架差异很大,影响了他们在医疗保健系统中的实践范围和整合。目的:本综述描绘了整个欧洲PTs的教育、资格和执业范围,突出了职称和监管方法的差异。方法:使用来自欧盟监管专业数据库的公开数据和来自代表欧洲药学技术人员的国家组织的数据进行回顾。对职称、资格等级、法规、项目持续时间和角色描述的数据进行提取和总结,以进行比较。结果:来自28个欧洲国家的调查结果显示,在药学技术人员资格水平(EQF 4-6)、培训时间(2-4.5年)和国家法规方面存在显著差异。监管范围从带有受保护标题的强制许可到缺乏监管。实践范围有所不同,从基本的配药和库存任务到更广泛的临床和技术责任。结论:欧洲药学技术人员的教育和监管格局仍然分散。尽管专业技术人员共同承担核心责任,但资格等级、项目持续时间和监管保护差异很大,限制了专业身份、流动性和劳动力规划。开发一个共享的欧洲教育和专业认可框架可以促进专业人员流动,减少专业和技能差距,并支持安全、高质量的药房服务,最终优化PTs对医疗保健系统的贡献。
{"title":"Pharmacy technicians in Europe: exploring the diversity in training, roles, and regulation.","authors":"Carolina Valeiro, Vitor Silva, Ângelo Jesus, João Joaquim, Cristiano Matos","doi":"10.1016/j.sapharm.2025.12.001","DOIUrl":"https://doi.org/10.1016/j.sapharm.2025.12.001","url":null,"abstract":"<p><strong>Background: </strong>Pharmacy technicians are increasingly recognized as essential healthcare professionals who contribute significantly to the delivery of pharmacy services. However, in Europe, the education, training, and regulatory frameworks governing pharmacy technicians vary substantially, influencing their scope of practice and integration within healthcare systems.</p><p><strong>Objective: </strong>This review maps the education, qualifications, and scope of practice of PTs across Europe, highlighting differences in professional titles and regulatory approaches.</p><p><strong>Methods: </strong>A review was conducted using publicly available data from the EU Regulated Professions Database and data collected from national organizations representing pharmacy technicians across Europe. Data on professional titles, qualification levels, regulations, program duration, and role delineation were extracted and summarized for comparison.</p><p><strong>Results: </strong>Findings from 28 European countries revealed significant variability in pharmacy technician qualification levels (EQF 4-6), training duration (2-4.5 years), and national regulation. Regulation ranges from mandatory licensing with protected titles to a lack of regulation. The scope of practice differs, from basic dispensing and inventory tasks to broader clinical and technical responsibilities.</p><p><strong>Conclusion: </strong>The landscape of pharmacy technician education and regulation in Europe remains fragmented. Although PTs share core responsibilities, qualification levels, program durations, and regulatory protections vary widely, limiting professional identity, mobility, and workforce planning. Developing a shared European framework for education and professional recognition could facilitate professional mobility, reduce professional and skill disparities, and support safe, high-quality pharmacy services, ultimately optimizing the contribution of PTs to healthcare systems.</p>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145702364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immigration timing modifies the association between medication non-adherence and cognitive function in older adults. 移民时间改变了老年人药物依从性与认知功能之间的关系。
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-01 DOI: 10.1016/j.sapharm.2025.11.011
Yuan Fang, Jayoung Han

Background: The aging U.S. immigrant population exhibits higher rates of dementia than U.S.-born residents, yet traditional diagnostic methods often fail to detect decline due to cultural and linguistic barriers. Unintentional medication non-adherence (MNA) may serve as an early, noninvasive marker of cognitive decline, but little is known about how immigration timing and other modifiers shape this relationship.

Methods: We analyzed data from 10,854 participants aged ≥65 years in the Health and Retirement Study (2012-2016). Cognitive function was assessed using standardized latent cognitive scores. Immigration status was classified as U.S.-born or immigrant, with immigrants further stratified by age at arrival (child/adolescent, early, middle, and late adulthood). Unintentional and intentional MNA were investigated separately, and a moderated moderation regression on cognitive function tested interactions between unintentional MNA, immigration status/timing, and education adjusted for demographic, socioeconomic, and health covariates.

Results: Unintentional MNA, being an immigrant (compared to non-immigrants), and older age at immigration were associated with lower cognitive scores, while higher education was protective. Significant two-way interactions indicated that immigration status (β = -0.38 ± 0.14, p = 0.0006), timing (β = -0.13 ± 0.03, p < 0.0001), and education (β = -0.09 ± 0.03, p = 0.003) moderated the MNA-cognition association, though three-way interaction was not significant. Subgroup analysis showed that unintentional MNA was generally linked to poorer cognition, but the moderating roles of immigration timing and education varied across ethnicity-immigration subgroups. The potential for residual confounding and other study limitations should be considered when interpreting these results.

Conclusion: In conclusion, unintentional MNA is a sensitive marker of cognitive decline, with risk magnified among immigrants who arrived in middle-late adulthood. Integrating adherence and immigration history into clinical assessments may improve early identification and guide targeted interventions for diverse older adults.

背景:老龄化的美国移民人口比美国出生的居民表现出更高的痴呆症发病率,然而由于文化和语言障碍,传统的诊断方法往往无法检测到衰退。无意药物依从性(MNA)可能是认知能力下降的早期、非侵入性标志,但对移民时间和其他修饰因素如何影响这种关系知之甚少。方法:我们分析了2012-2016年健康与退休研究中10854名年龄≥65岁的参与者的数据。使用标准化潜在认知评分评估认知功能。移民身份被划分为美国出生或移民,移民根据到达的年龄进一步分层(儿童/青少年,成年早期,中年和晚期)。无意MNA和有意MNA分别被调查,认知功能的适度回归测试了无意MNA、移民身份/时间和教育之间的相互作用,调整了人口、社会经济和健康协变量。结果:无意识的MNA,作为移民(与非移民相比),以及移民时年龄较大与较低的认知得分相关,而高等教育具有保护作用。结果表明,移民身份(β = -0.38±0.14,p = 0.0006)、移民时间(β = -0.13±0.03,p)是认知能力下降的敏感标志,且在成年中后期移民中风险放大。将依从性和移民史纳入临床评估可以改善早期识别并指导针对不同老年人的有针对性的干预措施。
{"title":"Immigration timing modifies the association between medication non-adherence and cognitive function in older adults.","authors":"Yuan Fang, Jayoung Han","doi":"10.1016/j.sapharm.2025.11.011","DOIUrl":"https://doi.org/10.1016/j.sapharm.2025.11.011","url":null,"abstract":"<p><strong>Background: </strong>The aging U.S. immigrant population exhibits higher rates of dementia than U.S.-born residents, yet traditional diagnostic methods often fail to detect decline due to cultural and linguistic barriers. Unintentional medication non-adherence (MNA) may serve as an early, noninvasive marker of cognitive decline, but little is known about how immigration timing and other modifiers shape this relationship.</p><p><strong>Methods: </strong>We analyzed data from 10,854 participants aged ≥65 years in the Health and Retirement Study (2012-2016). Cognitive function was assessed using standardized latent cognitive scores. Immigration status was classified as U.S.-born or immigrant, with immigrants further stratified by age at arrival (child/adolescent, early, middle, and late adulthood). Unintentional and intentional MNA were investigated separately, and a moderated moderation regression on cognitive function tested interactions between unintentional MNA, immigration status/timing, and education adjusted for demographic, socioeconomic, and health covariates.</p><p><strong>Results: </strong>Unintentional MNA, being an immigrant (compared to non-immigrants), and older age at immigration were associated with lower cognitive scores, while higher education was protective. Significant two-way interactions indicated that immigration status (β = -0.38 ± 0.14, p = 0.0006), timing (β = -0.13 ± 0.03, p < 0.0001), and education (β = -0.09 ± 0.03, p = 0.003) moderated the MNA-cognition association, though three-way interaction was not significant. Subgroup analysis showed that unintentional MNA was generally linked to poorer cognition, but the moderating roles of immigration timing and education varied across ethnicity-immigration subgroups. The potential for residual confounding and other study limitations should be considered when interpreting these results.</p><p><strong>Conclusion: </strong>In conclusion, unintentional MNA is a sensitive marker of cognitive decline, with risk magnified among immigrants who arrived in middle-late adulthood. Integrating adherence and immigration history into clinical assessments may improve early identification and guide targeted interventions for diverse older adults.</p>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A community pharmacy vaccination nudge intervention: Final results of a nationwide study. 社区药房疫苗轻推干预:一项全国性研究的最终结果。
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-28 DOI: 10.1016/j.sapharm.2025.11.010
Kenneth C Hohmeier, Andrea Brookhart, Olivia Kinney, Kayla Dillon, Chi-Yang Chiu, Kelsey D Frederick, Tracy Hagemann, Sujith Ramachandran, Justin Gatwood
<p><strong>Background: </strong>Community pharmacy is involved in an increasing number of clinical services, although this has been hindered by barriers related to workload and workflow. Borrowing from theories in behavioral economics, "nudges" aim to influence behavior through non-conscious decisions. One large area of potential impact for "nudge" theory is provider-facing screening and recommendations for vaccinations, but the manner in which these mechanisms have been adopted over time is not well understood. To date no evidence exists on the effectiveness of these "nudges" in the community pharmacy setting.</p><p><strong>Objective: </strong>The objective of this study is to report on final results of a pharmacist-targeted behavioral "nudge" to improve second dose completion rates for herpes zoster (HZ) vaccination. A secondary objective was to explore pharmacist acceptance of the nudge-based intervention.</p><p><strong>Methods: </strong>A multi-methods approach was used to assess this quality improvement exercise in a large community pharmacy chain, including vaccine uptake counts and semi-structured interviews with community pharmacists. Changes in second-dose completion of a two-dose HZ vaccine were abstracted from the pharmacy dispensing system and assessed over 17 months once the clinical decision support (CDS) intervention became active. The qualitative arm of the project involved semi-structured, in-depth telephone interviews with pharmacists. Qualitative data was assessed using the Consolidated Framework for Implementation Research (CFIR) to assess contextual barriers and enablers to the intervention. Linear trend analysis examined both series completion and dosing intervals over the observation period.</p><p><strong>Results: </strong>Thirty-six states were represented across 2271 pharmacies. Despite initial declines in completion percentages and increases in the vaccine dosing windows once the CDS system was implemented, overall improvements in both measures were realized over the course of the observation period (p < 0.01 for completion percentage trend; p < 0.001 for linear trend in mean inter-dose window). Themes derived from a total of 12 in-depth interviews included that the "nudge" positively impacted pharmacist performance expectancy, facilitated patient screening and recommendation process, integrated seamlessly into existing clinical workflows, and social influence positively impacted acceptance of "nudge."</p><p><strong>Conclusion: </strong>Community pharmacies may further their impact on public health via the use of "nudges" and other clinical decision support tools to support workflow integration. Pharmacists generally regard such interventions positively given their desire to provide more clinical services but not having adequate time to screen patients within workflow. To engage community pharmacies future research should identify means for technology to overcome workload constraints, such as "nudges" aimed at increasing
背景:社区药房参与了越来越多的临床服务,尽管这一直受到与工作量和工作流程相关的障碍的阻碍。“轻推”借用行为经济学理论,旨在通过无意识的决策影响行为。“助推”理论潜在影响的一个大领域是面向提供者的疫苗筛查和建议,但这些机制长期以来采用的方式尚未得到很好的理解。迄今为止,没有证据表明这些“推动”在社区药房环境中的有效性。目的:本研究的目的是报告以药剂师为目标的行为“推动”的最终结果,以提高带状疱疹(HZ)疫苗接种的第二剂完成率。第二个目标是探索药剂师对轻推干预的接受程度。方法:采用多方法评估大型社区连锁药店的质量改进工作,包括疫苗接种计数和对社区药剂师的半结构化访谈。从药房配药系统中提取两剂HZ疫苗的第二剂完成情况的变化,并在临床决策支持(CDS)干预开始后的17个月内进行评估。该项目的定性部分包括对药剂师进行半结构化、深入的电话采访。使用实施研究综合框架(CFIR)对定性数据进行评估,以评估干预的背景障碍和促成因素。线性趋势分析检查了整个观察期的系列完成和给药间隔。结果:有36个州的2271家药店。尽管实施CDS系统后,最初的完成率下降,疫苗剂量窗口增加,但在观察期间,这两项措施都实现了总体改善(p结论:社区药房可以通过使用“轻推”和其他临床决策支持工具来支持工作流程整合,从而进一步影响公共卫生。由于药剂师希望提供更多的临床服务,但没有足够的时间在工作流程中筛选患者,因此他们通常积极地看待这种干预措施。为了让社区药房参与进来,未来的研究应该确定技术克服工作量限制的方法,例如旨在增加筛查和依从性的“轻推”。
{"title":"A community pharmacy vaccination nudge intervention: Final results of a nationwide study.","authors":"Kenneth C Hohmeier, Andrea Brookhart, Olivia Kinney, Kayla Dillon, Chi-Yang Chiu, Kelsey D Frederick, Tracy Hagemann, Sujith Ramachandran, Justin Gatwood","doi":"10.1016/j.sapharm.2025.11.010","DOIUrl":"https://doi.org/10.1016/j.sapharm.2025.11.010","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Community pharmacy is involved in an increasing number of clinical services, although this has been hindered by barriers related to workload and workflow. Borrowing from theories in behavioral economics, \"nudges\" aim to influence behavior through non-conscious decisions. One large area of potential impact for \"nudge\" theory is provider-facing screening and recommendations for vaccinations, but the manner in which these mechanisms have been adopted over time is not well understood. To date no evidence exists on the effectiveness of these \"nudges\" in the community pharmacy setting.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The objective of this study is to report on final results of a pharmacist-targeted behavioral \"nudge\" to improve second dose completion rates for herpes zoster (HZ) vaccination. A secondary objective was to explore pharmacist acceptance of the nudge-based intervention.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A multi-methods approach was used to assess this quality improvement exercise in a large community pharmacy chain, including vaccine uptake counts and semi-structured interviews with community pharmacists. Changes in second-dose completion of a two-dose HZ vaccine were abstracted from the pharmacy dispensing system and assessed over 17 months once the clinical decision support (CDS) intervention became active. The qualitative arm of the project involved semi-structured, in-depth telephone interviews with pharmacists. Qualitative data was assessed using the Consolidated Framework for Implementation Research (CFIR) to assess contextual barriers and enablers to the intervention. Linear trend analysis examined both series completion and dosing intervals over the observation period.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Thirty-six states were represented across 2271 pharmacies. Despite initial declines in completion percentages and increases in the vaccine dosing windows once the CDS system was implemented, overall improvements in both measures were realized over the course of the observation period (p &lt; 0.01 for completion percentage trend; p &lt; 0.001 for linear trend in mean inter-dose window). Themes derived from a total of 12 in-depth interviews included that the \"nudge\" positively impacted pharmacist performance expectancy, facilitated patient screening and recommendation process, integrated seamlessly into existing clinical workflows, and social influence positively impacted acceptance of \"nudge.\"&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Community pharmacies may further their impact on public health via the use of \"nudges\" and other clinical decision support tools to support workflow integration. Pharmacists generally regard such interventions positively given their desire to provide more clinical services but not having adequate time to screen patients within workflow. To engage community pharmacies future research should identify means for technology to overcome workload constraints, such as \"nudges\" aimed at increasing","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The feasibility of implementing a hospital deprescribing behaviour change intervention and undertaking trial processes: A mixed methods evaluation 实施医院处方行为改变干预和进行试验的可行性:一种混合方法评价。
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-26 DOI: 10.1016/j.sapharm.2025.11.005
Sion Scott , Jacqueline Martin-Kerry , Megan Pritchard , Bethany Atkins , Allan B. Clark , Kelly Grant , David P. Alldred , Antony Colles , Amber Hammond , Katherine Murphy , Victoria L. Keevil , Ian Kellar , Martyn Patel , Erika Sims , Jo Taylor , David A. Turner , Miles Witham , David Wright , Debi Bhattacharya

Background

CompreHensive geriAtRician-led MEdication Review (CHARMER) is a behaviour change intervention designed to address the determinants of geriatricians and pharmacists deprescribing in hospital. CHARMER comprises a deprescribing action plan, deprescribing briefings, videos of successful deprescribing consultations, deprescribing case studies workshop and a deprescribing performance dashboard. This study aimed to evaluate the feasibility of undertaking a CHARMER definitive trial and inform primary outcome measure selection (90-day hospital readmission or patient quality of life (QoL)).

Methods

A two-arm purposive allocation feasibility study was undertaken in four hospitals (three intervention, one control). Intervention fidelity and acceptability, outcome data completeness and quality were evaluated alongside acceptability of data collection methods. The process evaluation explored these via interviews with staff and patients. Data were used to inform primary outcome measure selection.

Results

Eighteen geriatricians and pharmacists received the CHARMER intervention and 318 patients admitted to study wards were enrolled. 90-day hospital readmission data were available for 290 (91.2 %) patients. Sixty-six (20.8 %) were approached for consent to complete QoL measures; 25 (37.9 %) consented and 13 (52 %) completed at baseline and 90-day follow up.
All intervention components were implemented with acceptable fidelity; hospitals were unfamiliar with implementing action plans and unclear who should be involved with implementing the dashboard, leading to delays.

Conclusions

The CHARMER intervention is feasible to implement and given the low patient consent rate, 90-day readmission rate is the most appropriate primary outcome measure. Minor refinements to guidance will facilitate hospitals to undertake activities for implementation that are unfamiliar.

Clinical trial registration

The study was registered on ISRCTN (ISRCTN11899506).
背景:综合老年医生主导的药物审查(CHARMER)是一项行为改变干预措施,旨在解决老年医生和药剂师在医院开处方的决定因素。CHARMER包括处方解除行动计划、处方解除简报、处方解除成功咨询视频、处方解除案例研究研讨会和处方解除绩效仪表板。本研究旨在评估开展CHARMER最终试验的可行性,并为主要结局指标选择(90天再入院或患者生活质量(QoL))提供信息。方法:在4家医院(3个干预组,1个对照组)进行两组有目的分配可行性研究。评估干预的保真度和可接受性、结果数据的完整性和质量以及数据收集方法的可接受性。过程评估通过与工作人员和患者的访谈来探讨这些问题。数据用于主要结局测量指标的选择。结果:18名老年医师和药师接受了CHARMER干预,318名患者被纳入研究病房。290例(91.2%)患者可获得90天再入院数据。66例(20.8%)被要求同意完成生活质量测量;25人(37.9%)同意,13人(52%)完成了基线和90天的随访。所有干预成分均以可接受的保真度实施;医院不熟悉实施行动计划,也不清楚谁应该参与实施仪表板,这导致了延误。结论:CHARMER干预是可行的,考虑到患者同意率低,90天再入院率是最合适的主要结局指标。对指南稍加改进将有助于医院开展不熟悉的执行活动。临床试验注册:该研究在ISRCTN上注册(ISRCTN11899506)。
{"title":"The feasibility of implementing a hospital deprescribing behaviour change intervention and undertaking trial processes: A mixed methods evaluation","authors":"Sion Scott ,&nbsp;Jacqueline Martin-Kerry ,&nbsp;Megan Pritchard ,&nbsp;Bethany Atkins ,&nbsp;Allan B. Clark ,&nbsp;Kelly Grant ,&nbsp;David P. Alldred ,&nbsp;Antony Colles ,&nbsp;Amber Hammond ,&nbsp;Katherine Murphy ,&nbsp;Victoria L. Keevil ,&nbsp;Ian Kellar ,&nbsp;Martyn Patel ,&nbsp;Erika Sims ,&nbsp;Jo Taylor ,&nbsp;David A. Turner ,&nbsp;Miles Witham ,&nbsp;David Wright ,&nbsp;Debi Bhattacharya","doi":"10.1016/j.sapharm.2025.11.005","DOIUrl":"10.1016/j.sapharm.2025.11.005","url":null,"abstract":"<div><h3>Background</h3><div>CompreHensive geriAtRician-led MEdication Review (CHARMER) is a behaviour change intervention designed to address the determinants of geriatricians and pharmacists deprescribing in hospital. CHARMER comprises a deprescribing action plan, deprescribing briefings, videos of successful deprescribing consultations, deprescribing case studies workshop and a deprescribing performance dashboard. This study aimed to evaluate the feasibility of undertaking a CHARMER definitive trial and inform primary outcome measure selection (90-day hospital readmission or patient quality of life (QoL)).</div></div><div><h3>Methods</h3><div>A two-arm purposive allocation feasibility study was undertaken in four hospitals (three intervention, one control). Intervention fidelity and acceptability, outcome data completeness and quality were evaluated alongside acceptability of data collection methods. The process evaluation explored these via interviews with staff and patients. Data were used to inform primary outcome measure selection.</div></div><div><h3>Results</h3><div>Eighteen geriatricians and pharmacists received the CHARMER intervention and 318 patients admitted to study wards were enrolled. 90-day hospital readmission data were available for 290 (91.2 %) patients. Sixty-six (20.8 %) were approached for consent to complete QoL measures; 25 (37.9 %) consented and 13 (52 %) completed at baseline and 90-day follow up.</div><div>All intervention components were implemented with acceptable fidelity; hospitals were unfamiliar with implementing action plans and unclear who should be involved with implementing the dashboard, leading to delays.</div></div><div><h3>Conclusions</h3><div>The CHARMER intervention is feasible to implement and given the low patient consent rate, 90-day readmission rate is the most appropriate primary outcome measure. Minor refinements to guidance will facilitate hospitals to undertake activities for implementation that are unfamiliar.</div></div><div><h3>Clinical trial registration</h3><div>The study was registered on <em>ISRCTN</em> (<span><span>ISRCTN11899506</span><svg><path></path></svg></span>).</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 333-339"},"PeriodicalIF":2.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145649843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of pharmacist interventions as part of EAHOP - Enhancing allied health for older people in residential care. 作为EAHOP一部分的药剂师干预的结果-提高老年人住院护理的联合健康。
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-26 DOI: 10.1016/j.sapharm.2025.11.008
Rachel L Hill, Nathan M D'Cunha, Sam Kosari, Claire Pearce, Mark Naunton, Helen Holloway, Kasia Bail, Diane Gibson, Stephen Isbel

The EAHOP trial (Enhancing Allied Health for Older People in Residential Care) Outcomes of pharmacist interventions.

Background: The pharmacist has a critical role in the multidisciplinary team (MDT) when contributing to the care of older people living in residential aged care. The EAHOP study is a clinical trial that embedded a pharmacist within an MDT in a residential aged care home. This abstract reports on the pharmacy results of the study.

Method: This study used a mixed method to describe key pharmacy outcome measures of direct and indirect time per resident, number of recommendations accepted and to describe the thoughts, opinions and experience of key stakeholders.

Results: There were 124 recommendations made by the pharmacist for 34 residents, an average of 3.65 per resident, higher than the usual 2.7 recommendations per RMMR. At the GP case conferences 70 % were accepted, 9 % were declined and 21 % were not discussed. An average of 61 min direct time and 246 min of indirect time was spent per resident. Qualitative findings showed the pharmacy role improved care for residents by enhancing communication between health professionals, staff, residents and families.

Conclusion: The EAHOP model can supplement existing models of pharmacy intervention in residential care by providing organised multidisciplinary collaboration between the General Practitioner, nursing, pharmacist and allied health disciplines.

EAHOP试验(增强老年人住院护理的联合健康)药师干预的结果。背景:药剂师在多学科团队(MDT)中扮演着至关重要的角色,为居住在养老院的老年人提供护理。EAHOP研究是一项临床试验,将药剂师嵌入到养老院的MDT中。本文摘要报道了该研究的药学结果。方法:本研究采用混合方法来描述每个居民的直接和间接时间,接受的建议数量以及描述关键利益相关者的想法,意见和经验的关键药房结局指标。结果:药师对34名居民提出124条建议,平均每名居民3.65条建议,高于常规每名RMMR 2.7条建议。在全科医生病例会议上,70%被接受,9%被拒绝,21%未被讨论。每位居民平均花费61分钟直接时间和246分钟间接时间。定性研究结果表明,药房的作用通过加强卫生专业人员、工作人员、居民和家庭之间的沟通,改善了居民的护理。结论:EAHOP模式通过全科医生、护理、药剂师和相关卫生学科之间有组织的多学科合作,可以补充现有的住院护理药学干预模式。
{"title":"Outcomes of pharmacist interventions as part of EAHOP - Enhancing allied health for older people in residential care.","authors":"Rachel L Hill, Nathan M D'Cunha, Sam Kosari, Claire Pearce, Mark Naunton, Helen Holloway, Kasia Bail, Diane Gibson, Stephen Isbel","doi":"10.1016/j.sapharm.2025.11.008","DOIUrl":"https://doi.org/10.1016/j.sapharm.2025.11.008","url":null,"abstract":"<p><p>The EAHOP trial (Enhancing Allied Health for Older People in Residential Care) Outcomes of pharmacist interventions.</p><p><strong>Background: </strong>The pharmacist has a critical role in the multidisciplinary team (MDT) when contributing to the care of older people living in residential aged care. The EAHOP study is a clinical trial that embedded a pharmacist within an MDT in a residential aged care home. This abstract reports on the pharmacy results of the study.</p><p><strong>Method: </strong>This study used a mixed method to describe key pharmacy outcome measures of direct and indirect time per resident, number of recommendations accepted and to describe the thoughts, opinions and experience of key stakeholders.</p><p><strong>Results: </strong>There were 124 recommendations made by the pharmacist for 34 residents, an average of 3.65 per resident, higher than the usual 2.7 recommendations per RMMR. At the GP case conferences 70 % were accepted, 9 % were declined and 21 % were not discussed. An average of 61 min direct time and 246 min of indirect time was spent per resident. Qualitative findings showed the pharmacy role improved care for residents by enhancing communication between health professionals, staff, residents and families.</p><p><strong>Conclusion: </strong>The EAHOP model can supplement existing models of pharmacy intervention in residential care by providing organised multidisciplinary collaboration between the General Practitioner, nursing, pharmacist and allied health disciplines.</p>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145655631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying outcomes for evaluating the impact of pharmacist prescribing: A rapid overview of reviews. 确定评估药师处方影响的结果:快速回顾。
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-26 DOI: 10.1016/j.sapharm.2025.11.009
Ahmed Hassan Ali, Anais Essilini, Aaron Daunt, Michelle Flood, Caroline McCarthy, Judith Strawbridge, Barbara Clyne, Frank Moriarty

Objectives: Given the expansion of pharmacist prescribing, this study aims to identify and categorise outcomes reported in research evaluating impacts of pharmacist prescribing specifically for minor ailments (or common conditions) and in other broader contexts.

Methods: A rapid overview of reviews was conducted, searching PubMed, Embase, Cochrane Database of Systematic Reviews, and Epistemonikos using keywords relating to pharmacy/pharmacists, prescribing or minor ailments schemes, and evidence syntheses. Reviews evaluating the impact of any aspect of pharmacist prescribing were included if they reported ≥1 outcome assessing the impact of pharmacist prescribing. Data extraction focused on the clinical settings, disease areas/conditions, prescribing models and reported outcomes.

Results: Of 43 reviews included, 14 reported on outcomes of pharmacist prescribing in minor ailments, and 35 reviews in broader contexts (6 reporting both). Outcomes were categorised as clinical, drug-related/prescribing, patient-reported/experience, and economic/other outcomes. For minor ailments, 14 outcomes were identified, most frequently clinical cure or symptom resolution, and cost of service delivery (both reported in n = 8 reviews). In other prescribing contexts, 12 outcomes were reported, with general satisfaction being the most common (n = 18), followed by clinical effectiveness and healthcare resource use (both n = 15).

Conclusions: Capturing impact of pharmacist prescribing requires assessment of outcomes across multiple dimensions.

目的:鉴于药剂师处方的扩大,本研究旨在确定和分类研究报告的结果,评估药剂师处方对小病(或常见病)和其他更广泛背景下的影响。方法:检索PubMed、Embase、Cochrane Database of Systematic reviews和Epistemonikos,使用与药学/药剂师、处方或小病方案和证据综合相关的关键词,对文献进行快速综述。评价药师处方任何方面影响的综述,如果报告了≥1个评价药师处方影响的结果,则纳入评价。数据提取侧重于临床环境、疾病领域/条件、处方模型和报告的结果。结果:在纳入的43篇综述中,14篇报道了药剂师在小病中开处方的结果,35篇报道了更广泛的背景(6篇报道了两者)。结果分为临床、药物相关/处方、患者报告/经历和经济/其他结果。对于小病,确定了14个结果,最常见的是临床治愈或症状缓解,以及服务提供的成本(在n = 8篇综述中均有报道)。在其他处方环境中,报告了12个结果,其中一般满意度是最常见的(n = 18),其次是临床有效性和医疗资源利用(n = 15)。结论:获取药师处方的影响需要评估跨多个维度的结果。
{"title":"Identifying outcomes for evaluating the impact of pharmacist prescribing: A rapid overview of reviews.","authors":"Ahmed Hassan Ali, Anais Essilini, Aaron Daunt, Michelle Flood, Caroline McCarthy, Judith Strawbridge, Barbara Clyne, Frank Moriarty","doi":"10.1016/j.sapharm.2025.11.009","DOIUrl":"https://doi.org/10.1016/j.sapharm.2025.11.009","url":null,"abstract":"<p><strong>Objectives: </strong>Given the expansion of pharmacist prescribing, this study aims to identify and categorise outcomes reported in research evaluating impacts of pharmacist prescribing specifically for minor ailments (or common conditions) and in other broader contexts.</p><p><strong>Methods: </strong>A rapid overview of reviews was conducted, searching PubMed, Embase, Cochrane Database of Systematic Reviews, and Epistemonikos using keywords relating to pharmacy/pharmacists, prescribing or minor ailments schemes, and evidence syntheses. Reviews evaluating the impact of any aspect of pharmacist prescribing were included if they reported ≥1 outcome assessing the impact of pharmacist prescribing. Data extraction focused on the clinical settings, disease areas/conditions, prescribing models and reported outcomes.</p><p><strong>Results: </strong>Of 43 reviews included, 14 reported on outcomes of pharmacist prescribing in minor ailments, and 35 reviews in broader contexts (6 reporting both). Outcomes were categorised as clinical, drug-related/prescribing, patient-reported/experience, and economic/other outcomes. For minor ailments, 14 outcomes were identified, most frequently clinical cure or symptom resolution, and cost of service delivery (both reported in n = 8 reviews). In other prescribing contexts, 12 outcomes were reported, with general satisfaction being the most common (n = 18), followed by clinical effectiveness and healthcare resource use (both n = 15).</p><p><strong>Conclusions: </strong>Capturing impact of pharmacist prescribing requires assessment of outcomes across multiple dimensions.</p>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening for, and overcoming, ‘pill aversion’ in community pharmacy using a novel educational tool: Hard pill to swallow?™ 筛选,并克服,“药丸厌恶”在社区药房使用一种新的教育工具:硬药丸吞?
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-26 DOI: 10.1016/j.sapharm.2025.11.007
Alice. P. McCloskey , Johanne Nesbit , A.P. Rathbone , Nicola Vasey , Philippa. G. McCabe , Susan Flynn , Simran Bal , Katie Mulraney , Sarah Hamilton , Hashim Ali , Kyle Holebrooke-Steele , Yincent Tse , Emma. J. Lim

Background

Solid oral dosage forms (pills) are commonly dispensed but frequently patients struggle to take these (pill aversion). This is rarely identified or addressed in clinical practice. The KidzMed programme teaches children to swallow pills, but to date it has not been used to support adults with pill aversion.

Objectives

  • Assess in community pharmacy the acceptability of screening for pill aversion
  • Test an educational leaflet tailored for adults to support with pill swallowing

Methods

Participants were recruited via pre-defined inclusion and exclusion criteria using convenience sampling at three Liverpool-based community pharmacies over a one-month period. A screening questionnaire was completed and adults >18 years identified with pill aversion (score of 6+ on the PILL-5 screening tool) supplied with an adapted educational leaflet from the KidzMed programme. Successful pill swallowing using the leaflet was assessed via phone-call two weeks later. Institutional ethics reference (PBS/2023-23/01).

Results

Overall, 246 participants were screened, 9 % (n = 22) were identified as having pill aversion. There was an association with younger age and female gender. Follow-up showed that the leaflet was well received, participants found it useful, had changed their pill swallowing technique because of it, and shared this knowledge with others.

Conclusions

Pill aversion is an underexplored issue. The positive impact of the adapted leaflet in adults reflects the success of KidzMed for children. Further work is needed to confirm the association of age and gender with pill aversion, and determine translatability of the adapted leaflet to a wider audience and other healthcare settings.
背景:固体口服剂型(药片)通常被分配,但患者经常难以服用这些(药丸厌恶)。这在临床实践中很少被发现或解决。KidzMed项目教孩子们吞下药片,但迄今为止,它还没有被用来支持有药物厌恶症的成年人。目的:方法:参与者通过预先定义的纳入和排除标准,使用方便抽样在利物浦的三个社区药房招募,为期一个月。研究人员完成了一份筛查问卷,并向年龄在0岁至18岁之间的成年人(在pill -5筛查工具上得分为6+)提供了一份改编自KidzMed项目的教育传单。两周后,通过电话评估使用传单成功吞咽药丸的情况。机构伦理参考(PBS/2023-23/01)。结果:总的来说,246名参与者被筛选,9% (n = 22)被确定为有药丸厌恶。这与年龄较小和女性性别有关。随访结果显示,该传单反响良好,参与者发现它很有用,因此改变了他们的服药技巧,并与他人分享这些知识。结论:药物厌恶是一个未被充分探讨的问题。改编后的传单在成人中的积极影响反映了KidzMed在儿童中的成功。需要进一步的工作来确认年龄和性别与避孕药厌恶的关系,并确定改编后的传单对更广泛的受众和其他医疗保健机构的可翻译性。
{"title":"Screening for, and overcoming, ‘pill aversion’ in community pharmacy using a novel educational tool: Hard pill to swallow?™","authors":"Alice. P. McCloskey ,&nbsp;Johanne Nesbit ,&nbsp;A.P. Rathbone ,&nbsp;Nicola Vasey ,&nbsp;Philippa. G. McCabe ,&nbsp;Susan Flynn ,&nbsp;Simran Bal ,&nbsp;Katie Mulraney ,&nbsp;Sarah Hamilton ,&nbsp;Hashim Ali ,&nbsp;Kyle Holebrooke-Steele ,&nbsp;Yincent Tse ,&nbsp;Emma. J. Lim","doi":"10.1016/j.sapharm.2025.11.007","DOIUrl":"10.1016/j.sapharm.2025.11.007","url":null,"abstract":"<div><h3>Background</h3><div>Solid oral dosage forms (pills) are commonly dispensed but frequently patients struggle to take these (pill aversion). This is rarely identified or addressed in clinical practice. The KidzMed programme teaches children to swallow pills, but to date it has not been used to support adults with pill aversion.</div></div><div><h3>Objectives</h3><div><ul><li><span>•</span><span><div>Assess in community pharmacy the acceptability of screening for pill aversion</div></span></li><li><span>•</span><span><div>Test an educational leaflet tailored for adults to support with pill swallowing</div></span></li></ul></div></div><div><h3>Methods</h3><div>Participants were recruited via pre-defined inclusion and exclusion criteria using convenience sampling at three Liverpool-based community pharmacies over a one-month period. A screening questionnaire was completed and adults &gt;18 years identified with pill aversion (score of 6+ on the PILL-5 screening tool) supplied with an adapted educational leaflet from the KidzMed programme. Successful pill swallowing using the leaflet was assessed via phone-call two weeks later. Institutional ethics reference (PBS/2023-23/01).</div></div><div><h3>Results</h3><div>Overall, 246 participants were screened, 9 % (n = 22) were identified as having pill aversion. There was an association with younger age and female gender. Follow-up showed that the leaflet was well received, participants found it useful, had changed their pill swallowing technique because of it, and shared this knowledge with others.</div></div><div><h3>Conclusions</h3><div>Pill aversion is an underexplored issue. The positive impact of the adapted leaflet in adults reflects the success of KidzMed for children. Further work is needed to confirm the association of age and gender with pill aversion, and determine translatability of the adapted leaflet to a wider audience and other healthcare settings.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 340-347"},"PeriodicalIF":2.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare costs and cost determinants of minor ailments: A population-based retrospective cohort study. 小病的医疗费用和费用决定因素:一项基于人群的回顾性队列研究
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-26 DOI: 10.1016/j.sapharm.2025.11.006
Vanessa Koo, Diedron Lewis, Mhd Wasem Alsabbagh, Nardine Nakhla, William W L Wong

Background: Estimating the cost of providing healthcare services for minor ailments (MA) is essential to address the impact of newly legislated pharmacist prescribing on the burden these conditions place on healthcare budgets.

Objectives: This study aims to quantify the healthcare costs associated with minor ailment management in Ontario, describe patient characteristics by cost burden, and identify predictors of high-cost encounters.

Methods: This study employed a population-based retrospective cohort design, utilizing linked health administrative data from 2011 to 2019. The cost of care, in 2019 Canadian dollars, for up to 30 days after seeing a physician for MA was estimated from the perspective of a public payer. It included expenses from inpatient or physician visits, prescribed medication and emergency department visits. A gamma regression model with a logarithmic link was used to evaluate the impact of age, sex, income, residence, and a history of comorbidities on total cost.

Results: Over 34 million cases of MA were identified during the study period, with musculoskeletal sprains and strains accounting for 23.7 % of these cases. This ailment was also the costliest ($15.8 billion). Inpatient and physician care were the most expensive services. Higher costs were associated with older population groups, males, individuals with lower incomes, those living in urban spaces, and those with comorbidities.

Conclusion: Hospital and physician-based care pose a substantial financial burden to the Ontario government. An understanding of how the determinants of cost and care pathways influence health budgets is essential to inform decisions on more efficient yet equally effective strategies, such as pharmacist prescribing for MA.

背景:估计为小病(MA)提供医疗保健服务的成本是至关重要的,以解决新立法药剂师处方的负担,这些条件对医疗保健预算的影响。目的:本研究旨在量化安大略省与小病管理相关的医疗成本,通过成本负担描述患者特征,并确定高成本遭遇的预测因素。方法:本研究采用基于人群的回顾性队列设计,利用2011年至2019年的相关卫生管理数据。从公共支付方的角度估计,在看医生治疗MA后长达30天的护理费用(以2019年加元计算)。它包括住院或医生就诊、处方药和急诊就诊的费用。采用对数回归模型评估年龄、性别、收入、居住地和合并症史对总费用的影响。结果:在研究期间发现了3400多万例MA病例,其中肌肉骨骼扭伤和劳损占23.7%。这种疾病也是最昂贵的(158亿美元)。住院和内科护理是最昂贵的服务。较高的费用与老年人群、男性、收入较低的个人、生活在城市空间的人以及患有合并症的人有关。结论:医院和以医生为基础的护理给安大略省政府带来了巨大的财政负担。了解成本和护理途径的决定因素如何影响卫生预算,对于制定更有效但同样有效的战略(如药剂师开MA处方)至关重要。
{"title":"Healthcare costs and cost determinants of minor ailments: A population-based retrospective cohort study.","authors":"Vanessa Koo, Diedron Lewis, Mhd Wasem Alsabbagh, Nardine Nakhla, William W L Wong","doi":"10.1016/j.sapharm.2025.11.006","DOIUrl":"https://doi.org/10.1016/j.sapharm.2025.11.006","url":null,"abstract":"<p><strong>Background: </strong>Estimating the cost of providing healthcare services for minor ailments (MA) is essential to address the impact of newly legislated pharmacist prescribing on the burden these conditions place on healthcare budgets.</p><p><strong>Objectives: </strong>This study aims to quantify the healthcare costs associated with minor ailment management in Ontario, describe patient characteristics by cost burden, and identify predictors of high-cost encounters.</p><p><strong>Methods: </strong>This study employed a population-based retrospective cohort design, utilizing linked health administrative data from 2011 to 2019. The cost of care, in 2019 Canadian dollars, for up to 30 days after seeing a physician for MA was estimated from the perspective of a public payer. It included expenses from inpatient or physician visits, prescribed medication and emergency department visits. A gamma regression model with a logarithmic link was used to evaluate the impact of age, sex, income, residence, and a history of comorbidities on total cost.</p><p><strong>Results: </strong>Over 34 million cases of MA were identified during the study period, with musculoskeletal sprains and strains accounting for 23.7 % of these cases. This ailment was also the costliest ($15.8 billion). Inpatient and physician care were the most expensive services. Higher costs were associated with older population groups, males, individuals with lower incomes, those living in urban spaces, and those with comorbidities.</p><p><strong>Conclusion: </strong>Hospital and physician-based care pose a substantial financial burden to the Ontario government. An understanding of how the determinants of cost and care pathways influence health budgets is essential to inform decisions on more efficient yet equally effective strategies, such as pharmacist prescribing for MA.</p>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ensuring the quality use of medicines in clinical trials: A review and perspective on optimising the role of pharmacists. 确保临床试验中药物的使用质量:优化药师作用的综述与展望。
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-25 DOI: 10.1016/j.sapharm.2025.11.004
Beata Bajorek

Objectives: Given that a most clinical trials investigate potential or established medicines, it should be obvious that pharmacists, as 'medicines experts', would play a key role in such. The aim of this article was to narrate a perspective on the role of the pharmacist in clinical trials, drawing out the way that pharmacists are currently represented within clinical trials guidance documents.

Methods: This narrated review and perspective explored relevant international literature relating to clinical trial governance, particularly from the Australian setting where such documents have been recently developed and/or revised, providing a contemporary representation.

Results: Clinical trial guidance documents describing the role of pharmacists show that quality use of medicines principles are not well applied to the trial context. As such, pharmacists are underutilised in their role as medicines experts and as clinicians supporting optimal medicines use along the medication management pathway. Presently, guidance documents portray pharmacists as having largely administrative roles, focused on compliance with trial protocols, policies and legislation. Any clinical role appears relatively limited to drug handling. There is a need for capacity building in clinical trial to better recognise and utilise pharmacists' expertise, including them in the design, conduct, and leadership of clinical trials.

Conclusions: There is both scope and need to more directly include pharmacists in clinical trials. Wherever medicines are used, a pharmacist should be present and/or substantively involved in assuring the quality use of medicines, including within the full range of clinical trials. To support pharmacists, part of the global investment into clinical research should include an investment into clinical pharmacy services to ensure the quality use of medicines throughout the trial process alongside effective translation into clinical practice.

目的:鉴于大多数临床试验调查潜在的或已建立的药物,很明显,药剂师作为“药物专家”将在其中发挥关键作用。这篇文章的目的是叙述药师在临床试验中的作用的观点,绘制的方式,药剂师目前在临床试验指导文件中表示。方法:这篇叙述综述和观点探讨了与临床试验治理相关的国际文献,特别是来自澳大利亚的文献,这些文献最近被开发和/或修订,提供了一个当代的代表。结果:临床试验指导文件描述了药剂师的作用,表明药物质量使用原则没有很好地应用于试验环境。因此,药剂师作为药物专家和临床医生在药物管理途径中支持最佳药物使用的作用未得到充分利用。目前,指导文件将药剂师描述为主要具有行政作用,重点是遵守试验方案、政策和立法。任何临床作用似乎相对限于药物处理。临床试验需要能力建设,以便更好地认识和利用药剂师的专业知识,包括他们在临床试验的设计、实施和领导方面的专业知识。结论:在临床试验中更直接地纳入药师既有范围,也有必要。无论在哪里使用药物,药剂师都应该在场和/或实质性地参与确保药物的使用质量,包括在全范围的临床试验中。为了支持药剂师,对临床研究的部分全球投资应包括对临床药学服务的投资,以确保在整个试验过程中药物的质量使用,并有效地转化为临床实践。
{"title":"Ensuring the quality use of medicines in clinical trials: A review and perspective on optimising the role of pharmacists.","authors":"Beata Bajorek","doi":"10.1016/j.sapharm.2025.11.004","DOIUrl":"https://doi.org/10.1016/j.sapharm.2025.11.004","url":null,"abstract":"<p><strong>Objectives: </strong>Given that a most clinical trials investigate potential or established medicines, it should be obvious that pharmacists, as 'medicines experts', would play a key role in such. The aim of this article was to narrate a perspective on the role of the pharmacist in clinical trials, drawing out the way that pharmacists are currently represented within clinical trials guidance documents.</p><p><strong>Methods: </strong>This narrated review and perspective explored relevant international literature relating to clinical trial governance, particularly from the Australian setting where such documents have been recently developed and/or revised, providing a contemporary representation.</p><p><strong>Results: </strong>Clinical trial guidance documents describing the role of pharmacists show that quality use of medicines principles are not well applied to the trial context. As such, pharmacists are underutilised in their role as medicines experts and as clinicians supporting optimal medicines use along the medication management pathway. Presently, guidance documents portray pharmacists as having largely administrative roles, focused on compliance with trial protocols, policies and legislation. Any clinical role appears relatively limited to drug handling. There is a need for capacity building in clinical trial to better recognise and utilise pharmacists' expertise, including them in the design, conduct, and leadership of clinical trials.</p><p><strong>Conclusions: </strong>There is both scope and need to more directly include pharmacists in clinical trials. Wherever medicines are used, a pharmacist should be present and/or substantively involved in assuring the quality use of medicines, including within the full range of clinical trials. To support pharmacists, part of the global investment into clinical research should include an investment into clinical pharmacy services to ensure the quality use of medicines throughout the trial process alongside effective translation into clinical practice.</p>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145641296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of pharmacist prescribing on health-related outcomes in secondary care compared with medical prescribing or no treatment: A systematic review 与内科处方或不治疗相比,二级保健中药剂师处方对健康相关结果的影响:一项系统综述。
IF 2.8 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-11-24 DOI: 10.1016/j.sapharm.2025.11.003
Amina Omosalewa Akintunde, Ajlin Karaxhija, Raisa Laaksonen

Background

Pharmacist prescribing has gained momentum over the years and is currently utilised in Brazil, Canada, New Zealand, Poland, South Africa, United Kingdom (UK), and the United States of America (USA). While pharmacist prescribing has been associated with symptom improvement, reduced prescribing error rates, medication omissions, and improved medication access, the effects of pharmacist prescribing in secondary care have not been previously evaluated.

Objectives

This systematic review aimed to assess the effects of pharmacist prescribing on health-related outcomes in secondary care.

Methods

MEDLINE, Cochrane, CINAHL, Scopus, and Web of Science Core Collection databases were searched for studies published in English from database inception to October 3, 2024. Studies were included if the intervention was pharmacist prescribing and the outcomes were health-related and measurable. Narrative synthesis of the outcomes from included studies was conducted.

Results

A total of 21 studies from five countries (Australia, Egypt, Hong Kong, UK, USA) were included. Pharmacist prescribing significantly improved disease management, reduced the number of hospital revisits, improved blood pressure control, international normalised ratio control and decreased the number of adverse events when compared to medical prescribing. The evidence further suggests that the healthcare costs per patient per month, median cost of treatment, inpatient hospitalisations and emergency department admissions were significantly lower when pharmacists prescribed medicines. The evidence was low to moderate quality.

Conclusion

This systematic review provides evidence that pharmacist prescribing has a positive effect on therapeutic outcomes, and that pharmacist prescribing is comparable or better than medical prescribing in secondary care.
背景:药剂师处方多年来发展势头强劲,目前在巴西、加拿大、新西兰、波兰、南非、英国和美利坚合众国使用。虽然药剂师处方与症状改善、减少处方错误率、药物疏漏和改善药物可及性有关,但药剂师处方在二级保健中的效果此前尚未得到评估。目的:本系统综述旨在评估药师处方对二级保健中健康相关结局的影响。方法:检索MEDLINE、Cochrane、CINAHL、Scopus和Web of Science Core Collection数据库自建库至2024年10月3日发表的英文研究。如果干预是药剂师处方,并且结果与健康相关且可测量,则纳入研究。对纳入研究的结果进行叙述性综合。结果:共纳入来自5个国家(澳大利亚、埃及、香港、英国、美国)的21项研究。与内科处方相比,药剂师处方显著改善了疾病管理,减少了医院就诊次数,改善了血压控制,国际标准化比率控制,减少了不良事件的数量。证据进一步表明,当药剂师开药时,每位患者每月的医疗保健费用、治疗费用中位数、住院和急诊住院费用显著降低。证据质量为低到中等。结论:本系统评价提供了药师处方对治疗结果有积极影响的证据,并且药师处方在二级保健中与内科处方相当或更好。
{"title":"Effects of pharmacist prescribing on health-related outcomes in secondary care compared with medical prescribing or no treatment: A systematic review","authors":"Amina Omosalewa Akintunde,&nbsp;Ajlin Karaxhija,&nbsp;Raisa Laaksonen","doi":"10.1016/j.sapharm.2025.11.003","DOIUrl":"10.1016/j.sapharm.2025.11.003","url":null,"abstract":"<div><h3>Background</h3><div>Pharmacist prescribing has gained momentum over the years and is currently utilised in Brazil, Canada, New Zealand, Poland, South Africa, United Kingdom (UK), and the United States of America (USA). While pharmacist prescribing has been associated with symptom improvement, reduced prescribing error rates, medication omissions, and improved medication access, the effects of pharmacist prescribing in secondary care have not been previously evaluated.</div></div><div><h3>Objectives</h3><div>This systematic review aimed to assess the effects of pharmacist prescribing on health-related outcomes in secondary care.</div></div><div><h3>Methods</h3><div>MEDLINE, Cochrane, CINAHL, Scopus, and Web of Science Core Collection databases were searched for studies published in English from database inception to October 3, 2024. Studies were included if the intervention was pharmacist prescribing and the outcomes were health-related and measurable. Narrative synthesis of the outcomes from included studies was conducted.</div></div><div><h3>Results</h3><div>A total of 21 studies from five countries (Australia, Egypt, Hong Kong, UK, USA) were included. Pharmacist prescribing significantly improved disease management, reduced the number of hospital revisits, improved blood pressure control, international normalised ratio control and decreased the number of adverse events when compared to medical prescribing. The evidence further suggests that the healthcare costs per patient per month, median cost of treatment, inpatient hospitalisations and emergency department admissions were significantly lower when pharmacists prescribed medicines. The evidence was low to moderate quality.</div></div><div><h3>Conclusion</h3><div>This systematic review provides evidence that pharmacist prescribing has a positive effect on therapeutic outcomes, and that pharmacist prescribing is comparable or better than medical prescribing in secondary care.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 254-262"},"PeriodicalIF":2.8,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145641319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Research in Social & Administrative Pharmacy
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1