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Personality Disorder Symptoms in Intermittent Explosive Disorder: A Latent Class Analysis. 间歇性爆发障碍中的人格障碍症状:潜类分析
IF 2.1 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.34
Nicole K Ciesinski, Deborah A G Drabick, Mitchell E Berman, Michael S McCloskey

Intermittent explosive disorder (IED) is characterized by recurrent reactive aggression. IED is associated with significant personality pathology that is suggestive of higher levels of general personality disorder (PD). However, little is known about how personality factors impact the severity and presentation of IED. The present study employed a latent class analysis to assess for distinct PD symptom classes within IED and to evaluate whether these classes differed in terms of severity and behavioral presentation. Statistical and clinical indicators revealed a four-class model, with latent classes distinguished primarily on general levels of PD symptoms (low, moderate, high). However, the two moderate PD symptom classes were distinguished from other classes on avoidant PD. In addition, classes differed in terms of severity and presentation, suggesting important implications for both general PD and avoidant PD comorbidity within IED. Results provide further insight into the heterogeneity within IED and suggest a more nuanced approach in treating this serious condition.

间歇性爆发障碍(IED)的特点是反复出现反应性攻击行为。IED 与严重的人格病理学有关,这表明其具有较高程度的一般人格障碍 (PD)。然而,人们对人格因素如何影响 IED 的严重程度和表现形式知之甚少。本研究采用潜类分析法评估 IED 中不同的 PD 症状类别,并评估这些类别在严重程度和行为表现方面是否存在差异。统计和临床指标揭示了一个四级模型,潜类主要根据帕金森病症状的一般程度(低、中、高)来区分。然而,两个中度帕金森氏症症状等级与其他回避型帕金森氏症等级有所区别。此外,这些类别在严重程度和表现形式上也有所不同,这对 IED 中的一般 PD 和回避型 PD 合并症具有重要意义。研究结果进一步揭示了 IED 的异质性,并建议采用更细致的方法来治疗这一严重疾病。
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引用次数: 0
Bayesian Decision-Making Under Uncertainty in Borderline Personality Disorder. 边缘型人格障碍患者不确定情况下的贝叶斯决策。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.53
Mathi Manavalan, Xin Song, Tobias Nolte, Peter Fonagy, P Read Montague, Iris Vilares

Bayesian decision theory suggests that optimal decision-making should use and weigh prior beliefs with current information, according to their relative uncertainties. However, some characteristics of borderline personality disorder (BPD) patients, such as fast, drastic changes in the overall perception of themselves and others, suggest they may be underrelying on priors. Here, we investigated if BPD patients have a general deficit in relying on or combining prior with current information. We analyzed this by having BPD patients (n = 23) and healthy controls (n = 18) perform a coin-catching sensorimotor task with varying levels of prior and current information uncertainty. Our results indicate that BPD patients learned and used prior information and combined it with current information in a qualitatively Bayesian-like way. Our results show that, at least in a lower-level, nonsocial sensorimotor task, BPD patients can appropriately use both prior and current information, illustrating that potential deficits using priors may not be widespread or domain-general.

贝叶斯决策理论(Bayesian decision theory)认为,最佳决策应根据先验信念与当前信息的相对不确定性来使用和权衡它们。然而,边缘型人格障碍(BPD)患者的一些特征,如对自己和他人的总体看法发生快速、急剧的变化,表明他们可能对先验信念依赖不足。在此,我们研究了边缘型人格障碍患者在依赖或结合先验信息与当前信息方面是否存在普遍缺陷。我们通过让 BPD 患者(n = 23)和健康对照组(n = 18)在不同程度的先验信息和当前信息不确定性的情况下执行硬币捕捉感应运动任务来分析这一点。我们的结果表明,BPD 患者学习和使用先验信息,并以类似贝叶斯的方式将其与当前信息结合起来。我们的研究结果表明,至少在一个较低水平的、非社会性的感觉运动任务中,BPD 患者可以恰当地使用先验信息和当前信息,这说明使用先验信息的潜在缺陷可能并不普遍,也不具有领域普遍性。
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引用次数: 0
Commentary: Special Issue on Interpersonal Trust. 评论:人际信任特刊
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.10
Peter Fonagy, Chloe Campbell, Elizabeth Allison, Patrick Luyten

This commentary reviews the Journal of Personality Disorders special issue "Interpersonal Trust and Borderline Personality Disorder: Insights From Clinical Practice and Research," published in Volume 37, Number 5, October 2023.

这篇评论回顾了《人格障碍杂志》的特刊《人际信任与边缘型人格障碍》:临床实践与研究的启示》,发表于 2023 年 10 月第 37 卷第 5 期。
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引用次数: 0
Adverse Childhood Experiences Are Associated With Personality Disorder: A Prospective, Longitudinal Study. 童年的不良经历与人格障碍有关:一项前瞻性纵向研究。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.19
Rosalie Broekhof, Hans M Nordahl, Ingeborg Ulltveit-Moe Eikenæs, Sara G Selvik

There is a lack of studies that have prospectively examined adverse childhood experiences (ACEs) in association with a personality disorder (PD). Data from a sample of 8,199 adolescents first assessed for ACEs were linked with subsequent data from the Norwegian Patient Register in order to obtain diagnoses of a PD in adulthood (after a 14-year follow-up). We used logistic regression analysis. Any type of ACE gave a 3.8-fold higher risk of developing a PD. Abuse, more specifically emotional abuse, came out as one of the strongest predictors. Of the adolescents who developed a PD, approximately 90% had a history of ACE. The results of this study support the importance of assessing ACEs, such as abuse, neglect, and household dysfunction, in the diagnostic procedure and treatment for PD.

目前还缺乏对童年不良经历(ACE)与人格障碍(PD)相关性的前瞻性研究。我们将8,199名首次接受ACE评估的青少年样本数据与挪威患者登记册的后续数据联系起来,以获得成年后(14年随访后)的人格障碍诊断结果。我们采用了逻辑回归分析法。任何类型的ACE都会导致罹患帕金森病的风险增加3.8倍。虐待,尤其是情感虐待,是最有力的预测因素之一。在罹患帕金森氏症的青少年中,约 90% 有 ACE 史。这项研究的结果表明,在诊断和治疗肢端麻痹症的过程中,对虐待、忽视和家庭功能失调等 ACE 进行评估非常重要。
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引用次数: 0
Predictors of Effects in Brief Psychiatric Treatment for Borderline Personality Disorder. 边缘型人格障碍简短精神治疗效果的预测因素。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2023-11-01 DOI: 10.1521/pedi.2023.37.6.741
Loris Grandjean, Stéphane Kolly, Ueli Kramer

If evidence points to the equal efficacy of all bona fide treatments for borderline personality disorder (BPD) in general, it may not necessarily be true for a specific individual, nor do such general conclusions help in the triage of clients in clinical services. We investigated potential therapy outcome predictors for participants with a BPD diagnosis (N = 99). They were assessed on scales including the Outcome Questionnaire-45.2 (OQ-45), the Inventory of Interpersonal Problems-64, and the Borderline Symptom List. Our analyses revealed that individuals with low levels of symptom distress at intake had the smallest change in total OQ-45 score over the course of brief treatment, while the individuals with high levels of symptom distress had a mean large change in total score (-23). We observed that individuals with high symptom loads AND low levels of interpersonal problems at intake seemed to have the best progress.

如果有证据表明对边缘型人格障碍(BPD)的所有善意治疗在一般情况下都有同样的疗效,那么对于特定的个体来说,这可能并不一定是正确的,而且这样的一般性结论也无助于临床服务客户的分类。我们调查了BPD诊断参与者的潜在治疗结果预测因素(N = 99)。采用结果问卷-45.2 (OQ-45)、人际关系问题量表-64和边缘性症状表进行评估。我们的分析显示,在短暂的治疗过程中,摄入时症状困扰水平较低的个体的总OQ-45得分变化最小,而症状困扰水平较高的个体的总得分平均变化较大(-23)。我们观察到,高症状负荷和低水平的人际关系问题的个体似乎有最好的进展。
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引用次数: 0
The 8-Year Course of Acute Physical Pain Reported by Patients With Borderline Personality Disorder and Comparison Subjects With Other Personality Disorders. 边缘型人格障碍患者与其他人格障碍患者8年急性躯体疼痛病程的比较
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2023-11-01 DOI: 10.1521/pedi.2023.37.6.678
Alma M Bitran, Christina M Temes, Tess C Gecha, Isabel V Glass, Frances R Frankenburg, Garrett M Fitzmaurice, Mary C Zanarini

The present study examines the 8-year course of physical pain and its interference with functioning in patients with borderline personality disorder (BPD) and a comparison group of patients with other personality disorders (other-PD). Participants completed the Brief Pain Inventory (BPI) at five assessments, each separated by 2 years. Results showed that across all 13 domains assessed, participants with BPD reported significantly higher levels of acute physical pain and its functional interference than other-PD comparison subjects. The severity of physical pain and its interference with multiple domains of functioning were relatively stable over 8 years of assessment for both study groups. Within the BPD group, pain was significantly associated with older age, comorbid major depressive disorder (MDD), and history of a physically violent partner. Taken together, these results suggest that physical pain is a serious health issue for individuals with BPD that interferes with functioning across a wide spectrum of areas.

本研究探讨了边缘型人格障碍(BPD)患者和其他人格障碍(other- pd)患者8年的躯体疼痛病程及其对功能的干扰。参与者完成了简短疼痛量表(BPI)的五个评估,每个评估间隔2年。结果显示,在所有13个评估领域中,BPD患者报告的急性身体疼痛及其功能干扰水平明显高于其他pd对照受试者。在8年的评估中,两个研究组的身体疼痛的严重程度及其对多个功能领域的干扰相对稳定。在BPD组中,疼痛与年龄、共病性重度抑郁症(MDD)和伴侣暴力史显著相关。综上所述,这些结果表明,对于BPD患者来说,身体疼痛是一个严重的健康问题,它会干扰许多领域的功能。
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引用次数: 0
Specificity of Insecure Attachment in Adolescents With Borderline Personality Disorder in Psychiatric Inpatient and Community-Dwelling Adolescents. 精神科住院青少年和社区青少年边缘型人格障碍患者不安全依恋的特异性
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2023-11-01 DOI: 10.1521/pedi.2023.37.6.751
Onyinyechi Obi-Obasi, Kiana Cano, Carla Sharp

Borderline personality disorder (BPD) has been conceptualized as a disorder of attachment. However, the specificity of attachment insecurity to BPD in adolescents remains unclear. In this study, an inpatient sample (n = 521), of which 173 (33.2%) met the criteria for BPD, and a control sample of community-dwelling adolescents (n = 294) ages 12-17 were compared on a self-report measure of attachment security. In addition, hierarchical regression analyses were carried out to examine the incremental contribution of BPD symptoms, over and above internalizing and externalizing symptoms, in predicting attachment security. Results showed expected group differences such that adolescents with BPD evidenced higher levels of attachment insecurity to both fathers and mothers than psychiatric and community-dwelling controls. BPD features also incremented internalizing and externalizing problems associated with attachment security. However, because psychiatric controls also evidenced high levels of attachment insecurity, we conclude that while attachment insecurity is particularly salient for BPD, it is not necessarily specific to the disorder.

边缘型人格障碍(BPD)被定义为一种依恋障碍。然而,依恋不安全感对青少年BPD的特异性尚不清楚。在本研究中,住院患者样本(n = 521),其中173人(33.2%)符合BPD标准,与对照组(n = 294)年龄在12-17岁的社区居住青少年(n = 294)进行依恋安全自我报告测量的比较。此外,我们还进行了层次回归分析,以检验BPD症状在预测依恋安全性方面的增量贡献,而不是内在化和外在化症状。结果显示了预期的群体差异,例如,患有BPD的青少年对父亲和母亲的依恋不安全感水平高于精神病和社区生活对照组。BPD特性还增加了与附件安全性相关的内部化和外部化问题。然而,由于精神病学控制也证明了高水平的依恋不安全感,我们得出结论,虽然依恋不安全感在BPD中特别突出,但并不一定是这种疾病所特有的。
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引用次数: 0
Loneliness Is Associated With Lower Self- and Clinician-Rated Levels of Personality Functioning. 孤独与较低的自我和临床评定的人格功能水平有关。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2023-11-01 DOI: 10.1521/pedi.2023.37.6.724
Julia I Kunz, Anna Frey, Katja Bertsch, Barbara B Barton, Leonie Blei, Hannah M Schirle, Franziska Konvalin, Andrea Jobst, Richard Musil, Frank Padberg, Matthias A Reinhard

Personality disorders (PDs) are associated with interpersonal dysfunction, loneliness, and reduced social embeddedness. This study investigates loneliness and social network size in association with self- and clinician-rated personality functioning regarding the DSM-5's Alternative Model for Personality Disorders (AMPD). Eighty psychiatric inpatients including participants with and without PDs completed the Semi-structured Interview for Personality Functioning, the Level of Personality Functioning Scale - Brief Form, the UCLA Loneliness Scale, and the Social Network Index. Patients with PDs reported more loneliness and personality dysfunctioning than patients without PDs. Social network size did not differ between patient groups and showed lower correlations with personality functioning compared to loneliness. Loneliness was further associated with deficits in personality functioning. Deficits in distinct AMPD domains and loneliness may constitute transdiagnostically relevant factors that are related and mutually reinforcing. This could be important for identifying patients beyond PD diagnoses who are at risk of poor psychosocial functioning and require tailored psychotherapy.

人格障碍(pd)与人际功能障碍、孤独感和社会嵌入性降低有关。本研究根据DSM-5的人格障碍替代模型(AMPD)调查孤独感和社会网络大小与自我和临床评定的人格功能之间的关系。80名住院精神病患者,包括有和没有pd的参与者,完成了半结构化人格功能访谈、人格功能水平量表-简要表格、加州大学洛杉矶分校孤独量表和社会网络指数。患有pd的患者比没有pd的患者报告更多的孤独感和人格功能障碍。与孤独感相比,社会网络大小在患者群体之间没有差异,与人格功能的相关性也较低。孤独与人格功能缺陷进一步相关。不同AMPD结构域的缺陷和孤独感可能构成相互关联和相互加强的跨诊断相关因素。这对于识别PD诊断之外有社会心理功能不良风险并需要量身定制心理治疗的患者可能很重要。
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引用次数: 0
Self-Reported Gonadal Pubertal Timing Predicts Adolescent Borderline Personality Symptoms: Two Extended Replications With Prospective and Cross-Sectional Data. 自我报告性腺青春期时间预测青少年边缘性人格症状:前瞻性和横断面数据的两个扩展重复。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2023-11-01 DOI: 10.1521/pedi.2023.37.6.661
Kiran Boone, Diana J Whalen, Deanna M Barch, Joan L Luby, Katherine R Luking

The current study investigated the understudied relationship between pubertal timing and borderline personality disorder (BPD) symptoms in males and females. We conducted hierarchical linear regressions in a longitudinal Cohort 1 (N = 117) and a cross-sectional Cohort 2 (N = 127). Cohort 1: Pubertal timing was self-reported at age 10; BPD symptoms and covariates were assessed between ages 13 and 19. Cohort 2: All assessments were between ages 8 and 12. Covariates: race, age, internalizing and externalizing symptoms, and income-to-needs ratio. Sex differences were examined post hoc. In Cohort 1, early gonadal timing was associated with more BPD symptoms in females (beta = .46, p = .002), and late gonadal timing was associated with more BPD symptoms in males (beta = -.23, p = .035). In Cohort 2, early gonadal timing was associated with more BPD symptoms (beta = .21, p = .033) without sex moderation. Results indicate that early gonadal development could be a risk indicator for the emergence of BPD in adolescence, particularly in females, which could inform causal mechanisms and intervention targets.

本研究调查了青春期时间与男性和女性边缘性人格障碍(BPD)症状之间的关系。我们对纵向队列1 (N = 117)和横断面队列2 (N = 127)进行了分层线性回归。队列1:青春期时间在10岁时自我报告;在13岁至19岁之间评估BPD症状和协变量。队列2:所有的评估年龄在8到12岁之间。协变量:种族、年龄、内化和外化症状、收入需求比。性别差异在事后被检查。在队列1中,性腺时间提前与女性更多的BPD症状相关(β = 0.46, p = 0.002),性腺时间晚与男性更多的BPD症状相关(β = -)。23, p = .035)。在队列2中,性腺时间提前与更多的BPD症状相关(β = 0.21, p = 0.033),没有性别调节。结果表明,性腺发育早期可能是青春期(尤其是女性)出现BPD的危险指标,这可能为其因果机制和干预目标提供信息。
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引用次数: 0
Social and Occupational Functioning in Individuals With BPD: A Systematic Review. BPD患者的社会和职业功能:系统回顾。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2023-11-01 DOI: 10.1521/pedi.2023.37.6.691
Abhijatya Dhar, Phillipa Hay, Tanya Meade

This systematic review aimed to explore social and occupational functioning levels in individuals with BPD and whether this varies according to symptomatic status, age, or gender. A multi-database search was conducted for articles, and of the 1164 records identified, 19 were included in this review. Of the 15 studies reporting on social functioning, 13 indicated significant levels of impairment, and of the 14 studies reporting on global functioning, all indicated significant impairment across both clinical and in-remission populations. Occupational functioning was primarily assessed as either a part of global functioning or by subscales within social functioning, highlighting a lack of use of dedicated measures for its assessment. This systematic review found that individuals with BPD experience a range of significant impairments in functioning persisting across the lifespan. Further studies are warranted to explore levels of functional impairment across all functional domains and factors associated with continual functional impairment in this population.

本系统综述旨在探讨BPD患者的社会和职业功能水平,以及这是否因症状状态、年龄或性别而异。对文章进行了多数据库检索,在确定的1164条记录中,有19条被纳入本综述。在报告社会功能的15项研究中,13项表明存在显著程度的损害,而在报告整体功能的14项研究中,所有研究都表明在临床和缓解期人群中存在显著损害。职业功能主要作为全球功能的一部分进行评估,或通过社会功能中的子量表进行评估,突出表明缺乏使用专门的评估措施。该系统综述发现,BPD患者在一生中都会经历一系列显著的功能障碍。在这一人群中,有必要进一步研究所有功能域的功能损伤水平以及与持续功能损伤相关的因素。
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引用次数: 0
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Journal of Personality Disorders
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