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Psychiatrists' Perspectives on Prescription Decisions for Patients With Personality Disorders. 精神科医生对人格障碍患者处方决定的看法。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-06-01 DOI: 10.1521/pedi.2024.38.3.225
Peter Sand, Evelina Dervisoski, Sofia Kollia, Jennifer Strand, Flavio Di Leone

There is currently insufficient evidence for the use of a specific pharmacological treatment for personality disorders (PD). The research literature lacks a systematic exploration of clinicians' experiences of pharmacological treatment of PD. The aim of the qualitative study was to examine how psychiatrists make decisions about pharmacological treatment for patients with PD. The interviews were analyzed using inductive thematic analysis. The results showed that ambiguous guidelines had the effect that the psychiatrists often relied on their own experience, or that of their colleagues. As a basis for decisions concerning drug treatment, an interpersonal component was also identified. Some of the psychiatrists in the current study argued that medications may be part of the alliance-building with the patient and that medications were a way of tying the patient to the clinic. Our findings show that it is important to work on how the clinical guidelines should be implemented in practice.

目前还没有足够的证据表明需要对人格障碍(PD)采用特定的药物治疗。研究文献缺乏对临床医生在人格障碍药物治疗方面经验的系统探讨。本定性研究旨在探讨精神科医生如何决定对人格障碍患者进行药物治疗。研究采用归纳式主题分析法对访谈内容进行了分析。结果表明,模糊不清的指导方针导致精神科医生经常依赖自己或同事的经验。作为药物治疗决策的基础,人际关系因素也被确定下来。本研究中的一些精神科医生认为,药物治疗可能是与患者建立联盟的一部分,药物治疗是将患者与诊所联系在一起的一种方式。我们的研究结果表明,在实践中如何执行临床指南非常重要。
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引用次数: 0
Public Stigma and Continuum Beliefs Across Personality Disorder Severity Levels. 不同人格障碍严重程度的公众污名和连续性信念。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.75
Johannes Stricker, Laureen Hasenburg, Louisa Jakob, Tobias Weigl, Reinhard Pietrowsky

Stigmatizing attitudes toward persons with personality disorders are common. Preliminary evidence suggests that continuum beliefs (the view that presented symptoms lie on a continuum with normality) are associated with reduced personality disorder stigma. This study aimed to evaluate whether this association holds across the entire spectrum of personality disorder severity and whether greater personality disorder severity is linked to higher stigma. A general population sample (N = 848) completed questions about a vignette depicting mild, moderate, or severe personality disorder severity. Higher continuum beliefs were associated with a lower desire for social distance from persons with mild, moderate, or severe personality disorder. In addition, continuum beliefs were higher, and the desired social distance was lower toward a person with mild than a person with moderate or severe personality disorder. Thus, fostering continuum beliefs might aid in combating personality disorder stigma, including toward severely affected persons who experience strong stigmatization.

对人格障碍患者的污名化态度很常见。初步证据表明,连续体信念(认为表现出的症状与正常人处于一个连续体上)与人格障碍污名化程度的降低有关。本研究旨在评估这种关联在人格障碍严重程度的整个范围内是否成立,以及人格障碍严重程度越高是否与污名化程度越高有关。一个普通人群样本(N = 848)完成了有关描述轻度、中度或重度人格障碍严重程度的小故事的问题。较高的连续性信念与较低的与轻度、中度或重度人格障碍患者保持社会距离的愿望相关。此外,连续性信念越高,与轻度人格障碍患者保持社会距离的愿望就越低,而与中度或重度人格障碍患者保持社会距离的愿望就越低。因此,培养连续性信念可能有助于消除人格障碍的污名化,包括对遭受强烈污名化的严重患者的污名化。
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引用次数: 0
A State-Wide Initiative to Improve Health System Responses to People With Borderline Personality Disorder Symptoms in Crisis: A Retrospective Audit. 改善医疗系统对危机中边缘型人格障碍患者的应对措施的全州倡议:回顾性审计。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.87
Dianna R Bartsch, Cathy McLeod Everitt, Jana Bednarz, Cathy Ludbrook, Paul Cammell

Gold Card SA is a four-session structured psychological intervention offered soon after an acute crisis presentation to people with symptoms characteristic of borderline personality disorder. This study describes individual and system-level outcomes from a large-scale health-care improvement initiative to implement Gold Card SA across South Australia. An uncontrolled pre-post study design was utilized examining service user (n = 332) patient-reported outcome measures and hospital service utilization records (6 months before and after Gold Card SA). Mixed-effects negative binomial regression analysis revealed a significant decrease in rates of service utilization across emergency department presentations (63%), mental health-related inpatient admissions (65%), and bed days (82%). Linear mixed-effect regression indicated large reductions in borderline symptoms and nonspecific psychological distress, and small to moderate improvements in psychosocial functioning. People presenting with or experiencing borderline personality disorder symptoms may benefit from a brief crisis intervention embedded within a stepped care model.

南澳大利亚金卡"(Gold Card SA)是一种为期四节的结构化心理干预措施,在有边缘型人格障碍特征症状的人出现急性危机后不久提供。本研究介绍了在南澳大利亚州实施 "南澳大利亚金卡 "的大规模医疗保健改进计划所取得的个人和系统层面的成果。该研究采用了非对照的前后期研究设计,对服务使用者(n = 332)的患者报告结果和医院服务使用记录(南澳大利亚金卡实施前后 6 个月)进行了检查。混合效应负二项回归分析表明,急诊室就诊率(63%)、精神健康相关住院率(65%)和住院天数(82%)均显著下降。线性混合效应回归表明,边缘型症状和非特异性心理困扰大幅减少,社会心理功能得到小幅至中度改善。在阶梯式护理模式中嵌入简短的危机干预措施,可能会让出现边缘型人格障碍症状或正在经历边缘型人格障碍症状的人从中受益。
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引用次数: 0
Commentary: Special Issue on Interpersonal Trust. 评论:人际信任特刊
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.1
John F Clarkin

This commentary reviews the Journal of Personality Disorders special issue "Interpersonal Trust and Borderline Personality Disorder: Insights From Clinical Practice and Research," published in Volume 37, Number 5, October 2023.

这篇评论回顾了《人格障碍杂志》的特刊《人际信任与边缘型人格障碍》:临床实践与研究的启示》,发表于 2023 年 10 月第 37 卷第 5 期。
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引用次数: 0
Personality Disorder Symptoms in Intermittent Explosive Disorder: A Latent Class Analysis. 间歇性爆发障碍中的人格障碍症状:潜类分析
IF 2.1 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.34
Nicole K Ciesinski, Deborah A G Drabick, Mitchell E Berman, Michael S McCloskey

Intermittent explosive disorder (IED) is characterized by recurrent reactive aggression. IED is associated with significant personality pathology that is suggestive of higher levels of general personality disorder (PD). However, little is known about how personality factors impact the severity and presentation of IED. The present study employed a latent class analysis to assess for distinct PD symptom classes within IED and to evaluate whether these classes differed in terms of severity and behavioral presentation. Statistical and clinical indicators revealed a four-class model, with latent classes distinguished primarily on general levels of PD symptoms (low, moderate, high). However, the two moderate PD symptom classes were distinguished from other classes on avoidant PD. In addition, classes differed in terms of severity and presentation, suggesting important implications for both general PD and avoidant PD comorbidity within IED. Results provide further insight into the heterogeneity within IED and suggest a more nuanced approach in treating this serious condition.

间歇性爆发障碍(IED)的特点是反复出现反应性攻击行为。IED 与严重的人格病理学有关,这表明其具有较高程度的一般人格障碍 (PD)。然而,人们对人格因素如何影响 IED 的严重程度和表现形式知之甚少。本研究采用潜类分析法评估 IED 中不同的 PD 症状类别,并评估这些类别在严重程度和行为表现方面是否存在差异。统计和临床指标揭示了一个四级模型,潜类主要根据帕金森病症状的一般程度(低、中、高)来区分。然而,两个中度帕金森氏症症状等级与其他回避型帕金森氏症等级有所区别。此外,这些类别在严重程度和表现形式上也有所不同,这对 IED 中的一般 PD 和回避型 PD 合并症具有重要意义。研究结果进一步揭示了 IED 的异质性,并建议采用更细致的方法来治疗这一严重疾病。
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引用次数: 0
Bayesian Decision-Making Under Uncertainty in Borderline Personality Disorder. 边缘型人格障碍患者不确定情况下的贝叶斯决策。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.53
Mathi Manavalan, Xin Song, Tobias Nolte, Peter Fonagy, P Read Montague, Iris Vilares

Bayesian decision theory suggests that optimal decision-making should use and weigh prior beliefs with current information, according to their relative uncertainties. However, some characteristics of borderline personality disorder (BPD) patients, such as fast, drastic changes in the overall perception of themselves and others, suggest they may be underrelying on priors. Here, we investigated if BPD patients have a general deficit in relying on or combining prior with current information. We analyzed this by having BPD patients (n = 23) and healthy controls (n = 18) perform a coin-catching sensorimotor task with varying levels of prior and current information uncertainty. Our results indicate that BPD patients learned and used prior information and combined it with current information in a qualitatively Bayesian-like way. Our results show that, at least in a lower-level, nonsocial sensorimotor task, BPD patients can appropriately use both prior and current information, illustrating that potential deficits using priors may not be widespread or domain-general.

贝叶斯决策理论(Bayesian decision theory)认为,最佳决策应根据先验信念与当前信息的相对不确定性来使用和权衡它们。然而,边缘型人格障碍(BPD)患者的一些特征,如对自己和他人的总体看法发生快速、急剧的变化,表明他们可能对先验信念依赖不足。在此,我们研究了边缘型人格障碍患者在依赖或结合先验信息与当前信息方面是否存在普遍缺陷。我们通过让 BPD 患者(n = 23)和健康对照组(n = 18)在不同程度的先验信息和当前信息不确定性的情况下执行硬币捕捉感应运动任务来分析这一点。我们的结果表明,BPD 患者学习和使用先验信息,并以类似贝叶斯的方式将其与当前信息结合起来。我们的研究结果表明,至少在一个较低水平的、非社会性的感觉运动任务中,BPD 患者可以恰当地使用先验信息和当前信息,这说明使用先验信息的潜在缺陷可能并不普遍,也不具有领域普遍性。
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引用次数: 0
Commentary: Special Issue on Interpersonal Trust. 评论:人际信任特刊
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.10
Peter Fonagy, Chloe Campbell, Elizabeth Allison, Patrick Luyten

This commentary reviews the Journal of Personality Disorders special issue "Interpersonal Trust and Borderline Personality Disorder: Insights From Clinical Practice and Research," published in Volume 37, Number 5, October 2023.

这篇评论回顾了《人格障碍杂志》的特刊《人际信任与边缘型人格障碍》:临床实践与研究的启示》,发表于 2023 年 10 月第 37 卷第 5 期。
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引用次数: 0
Adverse Childhood Experiences Are Associated With Personality Disorder: A Prospective, Longitudinal Study. 童年的不良经历与人格障碍有关:一项前瞻性纵向研究。
IF 2.3 3区 医学 Q3 PSYCHIATRY Pub Date : 2024-02-01 DOI: 10.1521/pedi.2024.38.1.19
Rosalie Broekhof, Hans M Nordahl, Ingeborg Ulltveit-Moe Eikenæs, Sara G Selvik

There is a lack of studies that have prospectively examined adverse childhood experiences (ACEs) in association with a personality disorder (PD). Data from a sample of 8,199 adolescents first assessed for ACEs were linked with subsequent data from the Norwegian Patient Register in order to obtain diagnoses of a PD in adulthood (after a 14-year follow-up). We used logistic regression analysis. Any type of ACE gave a 3.8-fold higher risk of developing a PD. Abuse, more specifically emotional abuse, came out as one of the strongest predictors. Of the adolescents who developed a PD, approximately 90% had a history of ACE. The results of this study support the importance of assessing ACEs, such as abuse, neglect, and household dysfunction, in the diagnostic procedure and treatment for PD.

目前还缺乏对童年不良经历(ACE)与人格障碍(PD)相关性的前瞻性研究。我们将8,199名首次接受ACE评估的青少年样本数据与挪威患者登记册的后续数据联系起来,以获得成年后(14年随访后)的人格障碍诊断结果。我们采用了逻辑回归分析法。任何类型的ACE都会导致罹患帕金森病的风险增加3.8倍。虐待,尤其是情感虐待,是最有力的预测因素之一。在罹患帕金森氏症的青少年中,约 90% 有 ACE 史。这项研究的结果表明,在诊断和治疗肢端麻痹症的过程中,对虐待、忽视和家庭功能失调等 ACE 进行评估非常重要。
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引用次数: 0
Predictors of Effects in Brief Psychiatric Treatment for Borderline Personality Disorder. 边缘型人格障碍简短精神治疗效果的预测因素。
IF 2.1 3区 医学 Q3 PSYCHIATRY Pub Date : 2023-11-01 DOI: 10.1521/pedi.2023.37.6.741
Loris Grandjean, Stéphane Kolly, Ueli Kramer

If evidence points to the equal efficacy of all bona fide treatments for borderline personality disorder (BPD) in general, it may not necessarily be true for a specific individual, nor do such general conclusions help in the triage of clients in clinical services. We investigated potential therapy outcome predictors for participants with a BPD diagnosis (N = 99). They were assessed on scales including the Outcome Questionnaire-45.2 (OQ-45), the Inventory of Interpersonal Problems-64, and the Borderline Symptom List. Our analyses revealed that individuals with low levels of symptom distress at intake had the smallest change in total OQ-45 score over the course of brief treatment, while the individuals with high levels of symptom distress had a mean large change in total score (-23). We observed that individuals with high symptom loads AND low levels of interpersonal problems at intake seemed to have the best progress.

如果有证据表明对边缘型人格障碍(BPD)的所有善意治疗在一般情况下都有同样的疗效,那么对于特定的个体来说,这可能并不一定是正确的,而且这样的一般性结论也无助于临床服务客户的分类。我们调查了BPD诊断参与者的潜在治疗结果预测因素(N = 99)。采用结果问卷-45.2 (OQ-45)、人际关系问题量表-64和边缘性症状表进行评估。我们的分析显示,在短暂的治疗过程中,摄入时症状困扰水平较低的个体的总OQ-45得分变化最小,而症状困扰水平较高的个体的总得分平均变化较大(-23)。我们观察到,高症状负荷和低水平的人际关系问题的个体似乎有最好的进展。
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引用次数: 0
The 8-Year Course of Acute Physical Pain Reported by Patients With Borderline Personality Disorder and Comparison Subjects With Other Personality Disorders. 边缘型人格障碍患者与其他人格障碍患者8年急性躯体疼痛病程的比较
IF 2.1 3区 医学 Q3 PSYCHIATRY Pub Date : 2023-11-01 DOI: 10.1521/pedi.2023.37.6.678
Alma M Bitran, Christina M Temes, Tess C Gecha, Isabel V Glass, Frances R Frankenburg, Garrett M Fitzmaurice, Mary C Zanarini

The present study examines the 8-year course of physical pain and its interference with functioning in patients with borderline personality disorder (BPD) and a comparison group of patients with other personality disorders (other-PD). Participants completed the Brief Pain Inventory (BPI) at five assessments, each separated by 2 years. Results showed that across all 13 domains assessed, participants with BPD reported significantly higher levels of acute physical pain and its functional interference than other-PD comparison subjects. The severity of physical pain and its interference with multiple domains of functioning were relatively stable over 8 years of assessment for both study groups. Within the BPD group, pain was significantly associated with older age, comorbid major depressive disorder (MDD), and history of a physically violent partner. Taken together, these results suggest that physical pain is a serious health issue for individuals with BPD that interferes with functioning across a wide spectrum of areas.

本研究探讨了边缘型人格障碍(BPD)患者和其他人格障碍(other- pd)患者8年的躯体疼痛病程及其对功能的干扰。参与者完成了简短疼痛量表(BPI)的五个评估,每个评估间隔2年。结果显示,在所有13个评估领域中,BPD患者报告的急性身体疼痛及其功能干扰水平明显高于其他pd对照受试者。在8年的评估中,两个研究组的身体疼痛的严重程度及其对多个功能领域的干扰相对稳定。在BPD组中,疼痛与年龄、共病性重度抑郁症(MDD)和伴侣暴力史显著相关。综上所述,这些结果表明,对于BPD患者来说,身体疼痛是一个严重的健康问题,它会干扰许多领域的功能。
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引用次数: 0
期刊
Journal of Personality Disorders
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