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Neuroradiology of acute pathologies in adults with hematologic malignancies: a pictorial review. 成人血液恶性肿瘤急性病理的神经放射学:一篇图片综述。
IF 2.8 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-11-01 Epub Date: 2023-03-22 DOI: 10.21037/qims-22-1201
Carlo A Mallio, Caterina Bernetti, Gennaro Castiello, Emma Gangemi, Valeria Tomarchio, Ombretta Annibali, Luigi Rigacci, Johan Van Goethem, Paul M Parizel, Bruno Beomonte Zobel, Carlo C Quattrocchi

Hematopoietic and lymphoid tumors are a heterogeneous group of diseases including lymphomas, multiple myeloma (MM), and leukemias. These diseases are associated with systemic involvement and various clinical presentations including acute neurological deficits. Adult patients with hematologic malignancies (HM) are at risk for developing a wide array of acute conditions involving the nervous system. HM in adults may present as tumoral masses responsible for mass effect, possibly resulting in acute neurological signs and symptoms caused by tumor growth with compression of central nervous system (CNS) structures. Moreover, as result of the hematologic disease itself or due to systemic treatments, hematologic patients are at risk for vascular pathologies, such as ischemic, thrombotic, and hemorrhagic disorders due to the abnormal coagulation status. The onset of these disorders is often with acute neurologic signs or symptoms. Lastly, it is well known that patients with HM can have impaired function of the immune system. Thus, CNS involvement due to immune-related diseases such as mycotic, parasitic, bacterial, and viral infections linked to immunodeficiency, together with immune reconstitution inflammatory syndrome, are frequently seen in hematologic patients. Knowledge of the etiology and expected CNS imaging findings in patients with HM is of great importance to reach a fast and correct diagnosis and guide treatment choices. In this manuscript, we review the computed tomography (CT) and magnetic resonance findings of these conditions which can be related to the disease itself and/or to their treatments.

造血和淋巴肿瘤是一组异质性疾病,包括淋巴瘤、多发性骨髓瘤(MM)和白血病。这些疾病与全身受累和各种临床表现有关,包括急性神经功能障碍。成年患者血液恶性肿瘤(HM)是在发展广泛的急性条件涉及神经系统的风险。成人HM可能表现为肿瘤肿块,导致肿块效应,可能导致急性神经系统体征和症状,由肿瘤生长压迫中枢神经系统(CNS)结构引起。此外,由于血液病本身或由于全身治疗,血液病患者有发生血管病变的风险,如由于凝血状态异常引起的缺血性、血栓性和出血性疾病。这些疾病的发病通常伴有急性神经体征或症状。最后,众所周知,HM患者的免疫系统功能受损。因此,与免疫缺陷相关的真菌、寄生虫、细菌和病毒感染以及免疫重建炎症综合征等免疫相关疾病累及中枢神经系统在血液病患者中很常见。了解HM患者的病因和预期的中枢神经系统影像学表现对于快速正确诊断和指导治疗选择具有重要意义。在这篇文章中,我们回顾了计算机断层扫描(CT)和磁共振的发现,这些情况可能与疾病本身和/或治疗有关。
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引用次数: 0
Cultural Origin and Minority Shareholder Expropriation: Historical Evidence 文化起源与小股东征用:历史证据
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-25 DOI: 10.1111/1475-679X.12517
ZHIHUI GU, WEI SUN, FRANK S. ZHOU

Can culture explain regional differences in minority shareholder expropriation? Examining regional variation in China, we document that the influence of historical Confucian values persists, despite decades of political movements clamping down on these values, and that these values reduce minority shareholder expropriation in local public firms. The effect on minority shareholder expropriation, in part, operates through the establishment of oversight mechanisms (i.e., greater financial reporting quality and dividend payouts) that constrain expropriation. The findings have important implications for understanding the origins of enduring regional differences in minority shareholder expropriation and capital market development.

文化能否解释小股东征用的地区差异?通过研究中国的地区差异,我们发现,尽管数十年来政治运动一直在压制儒家价值观,但这些价值观对历史上儒家价值观的影响依然存在,而且这些价值观减少了当地上市公司对小股东的征用。对小股东征用的影响在一定程度上是通过建立监督机制(即提高财务报告质量和股息支付)来实现的,这种机制限制了征用。这些发现对于理解小股东征用和资本市场发展方面长期存在的地区差异的根源具有重要意义。
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引用次数: 0
Transparency in Hierarchies 等级制度的透明度
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-20 DOI: 10.1111/1475-679X.12516
CHRISTIAN HOFMANN, RAFFI J. INDJEJIKIAN

We use an agency model to address the benefits and costs of transparency in a hierarchical organization in which the principal employs a manager entrusted with contracting authority and several workers, all under conditions of moral hazard. We define the principal's transparency choices as a decision to allow workers to observe their coworkers’ performances (observability) and as an investment in monitoring worker performance (precision). We find that whereas precision alleviates agency conflicts as expected, observability can exacerbate agency conflicts, especially if the manager's interests are misaligned sufficiently with those of the principal. Our results suggest several testable hypotheses including predictions that opaque performance measurement practices are well suited for small organizational units at lower hierarchical ranks, and in settings where the sensitivity-precision of the available measures is low, workers’ performances are correlated positively, and managerial productivity is modest.

我们使用一个代理模型来探讨在一个层级组织中透明度的收益和成本问题,在这个组织中,委托人雇用了一名受托拥有订约权的经理和若干名工人,所有这些人都处于道德风险的条件下。我们将委托人的透明度选择定义为允许工人观察同事表现的决定(可观察性)和监督工人表现的投资(精确性)。我们发现,精确性可以缓解代理冲突,而可观察性则会加剧代理冲突,尤其是当管理者的利益与委托人的利益严重不一致时。我们的研究结果提出了几个可检验的假设,其中包括不透明的绩效衡量方法非常适合等级较低的小型组织单位,以及在可用衡量标准的灵敏度-精确度较低、工人的绩效呈正相关、管理者的生产率不高的情况下。
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引用次数: 0
Issue Information - Request for Registered Reports 问题信息-注册报告请求
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-19 DOI: 10.1111/1475-679X.12511
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引用次数: 0
Issue Information - Standing Call for Proposals for 发布信息-长期征求建议书
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-19 DOI: 10.1111/1475-679X.12512
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引用次数: 0
Treatment of Accounting Changes and Covenant Violation Errors 会计变更和违反公约错误的处理办法
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-19 DOI: 10.1111/1475-679X.12515
CHUNMEI ZHU

GAAP provisions in loan contracts specify how to address the effect of accounting changes on financial covenants. I document a pronounced upward trend in and the dominance of frozen-on-request (FOR) GAAP provisions, which incorporate accounting changes unless either the borrower or the lender requests a freeze. FOR GAAP streamlines the process of incorporating accounting changes into covenant calculations by obviating the need for renegotiations and prevents opportunistic GAAP freezes by requiring good faith renegotiations. Therefore, FOR GAAP is more likely to incorporate accounting changes beneficial to covenant informativeness, leading to lower false positives (i.e., Type I errors of financial covenant violations) and false negatives (i.e., Type II errors of financial covenant violations). Based on a large sample of loan contracts, I find that FOR GAAP decreases false positives and false negatives after controlling for self-selection bias and that the decrease is more pronounced when accounting changes relevant to financial covenants are more significant. My study provides new evidence of the role accounting standards and GAAP provisions play in debt contracting efficiency.

贷款合同中的 GAAP 条款规定了如何处理会计变更对财务契约的影响。根据我的记录,除非借款人或贷款人要求冻结,否则按要求冻结的公认会计原则(FOR)条款会纳入会计变更,而且这种条款呈明显上升趋势并占据主导地位。FOR GAAP 简化了将会计变更纳入契约计算的过程,避免了重新谈判的需要,并通过要求善意的重新谈判来防止机会主义的 GAAP 冻结。因此, FOR GAAP 更有可能纳入有利于契约信息性的会计变更,从而降低假阳性(即违反财务契约的第一类错误)和假阴性(即违反财务契约的第二类错误)。基于大量的贷款合同样本,我发现在控制了自我选择偏差之后,FOR GAAP 会降低假阳性和假阴性,而且当与财务契约相关的会计变更更为显著时,假阳性和假阴性的降低更为明显。我的研究为会计准则和公认会计原则条款在债务契约效率中的作用提供了新的证据。
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引用次数: 0
Issue Information - Request for Papers 问题信息-论文征集
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-19 DOI: 10.1111/1475-679X.12449
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引用次数: 0
What Role Do Boards Play in Companies with Visionary CEOs? 董事会在拥有远见卓识的首席执行官的公司中扮演什么角色?
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-16 DOI: 10.1111/1475-679X.12514
XU JIANG, VOLKER LAUX

Visionary CEOs have strong beliefs about the right course of action for their firms. How should a board of directors that does not necessarily share the visionary CEO's confidence advise and monitor the CEO? We consider a model in which the board can acquire costly information about the firm's optimal strategic direction. The board not only advises the CEO on strategy, but also must approve it, and the CEO exerts effort to implement the strategy. We find that the board gathers less information when the CEO believes more strongly in his vision. Further, depending on the strength of the CEO's belief bias, the board either plays an advisory role, a monitoring role, or a rubberstamping role. The model predicts that in firms that are led by highly visionary CEOs, boards are passive in that they acquire little information and rubberstamp the visionary's proposal. Nevertheless, shareholders prefer the visionary over an unbiased manager in industries in which obtaining information about the correct course of action is difficult and costly.

富有远见的首席执行官对公司的正确发展方向有着坚定的信念。董事会并不一定与有远见的首席执行官有同样的信心,那么董事会应该如何为首席执行官提供建议并对其进行监督呢?我们考虑了一个模型,在这个模型中,董事会可以获得有关公司最佳战略方向的高成本信息。董事会不仅要向首席执行官提供战略建议,还必须批准战略,首席执行官则要努力实施战略。我们发现,当首席执行官更坚信自己的愿景时,董事会收集的信息就会减少。此外,根据首席执行官信念偏差的强度,董事会要么扮演顾问角色,要么扮演监督角色,要么扮演橡皮图章角色。该模型预测,在由极具远见卓识的首席执行官领导的公司中,董事会是被动的,因为他们获取的信息很少,而且会对远见卓识者的提议盖橡皮图章。尽管如此,在难以获得有关正确行动方针的信息且成本高昂的行业中,股东更喜欢有远见的人,而不是不偏不倚的经理人。
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引用次数: 0
Regulatory Transparency and Regulators’ Effort: Evidence from Public Release of the SEC's Review Work 监管透明度与监管者的努力:公开发布美国证券交易委员会审查工作的证据
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-12 DOI: 10.1111/1475-679X.12513
RUI GUO, Xiaoli (Shaolee) Tian

Using the public release of comment letters on EDGAR to capture a regime shift toward regulatory transparency, we examine whether an increase in transparency affects regulators’ effort and work performance. We find that the SEC staff reviews more filings and more documents per filing following the disclosure regime shift. These effects are incrementally stronger for firms with comment letters that are expected to attract greater investor or public monitoring. Furthermore, under the new regime, reviews are more timely. Upon the regime switch, the likelihood of a restatement (receiving a comment letter) decreases (increases) for filings that are reviewed. After receiving a comment letter, a firm with signs of potential fraud is more likely to be investigated, and this effect becomes more pronounced under the new regime. Altogether, our findings suggest that publicly disclosing regulators’ work output can mitigate moral hazard (i.e., increase regulators’ work input), improving their work performance.

我们利用 EDGAR 上公开发布的评论信来捕捉监管透明度的制度转变,研究透明度的提高是否会影响监管者的努力和工作绩效。我们发现,在信息披露制度转变后,美国证券交易委员会的工作人员审查了更多的申报文件,每份申报文件审查的文件数量也更多。对于有评论信的公司来说,这些影响会逐渐增强,因为这些评论信预计会吸引更多投资者或公众的监督。此外,在新制度下,审查更加及时。制度转换后,被审查的申报文件重述(收到意见函)的可能性会降低(增加)。在收到意见函后,有潜在欺诈迹象的公司更有可能受到调查,而在新制度下,这种影响变得更加明显。总之,我们的研究结果表明,公开披露监管者的工作产出可以减轻道德风险(即增加监管者的工作投入),提高他们的工作绩效。
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引用次数: 0
Information Complementarities and the Dynamics of Transparency Shock Spillovers 信息互补性与透明度冲击溢出效应的动态变化
IF 4.4 2区 管理学 Q1 BUSINESS, FINANCE Pub Date : 2023-10-03 DOI: 10.1111/1475-679X.12510
SHANTANU BANERJEE, SUDIPTO DASGUPTA, RUI SHI, JIALI YAN

We show that information complementarities play an important role in the spillover of transparency shocks. We exploit the revelation of financial misconduct by S&P 500 firms, and in a “Stacked Difference-in-Differences” design, find that the implied cost of capital increases for “close” industry peers of the fraudulent firms relative to “distant” industry peers. The spillover effect is particularly strong when the close peers and the fraudulent firm share common analyst coverage and common institutional ownership, which have been shown to be powerful proxies for fundamental linkages and information complementarities. We provide evidence that increase in the cost of capital of peer firms is due, at least in part, to “beta shocks.” Disclosure by close peers—especially those with co-coverage and co-ownership links—also increases following fraud revelation. Although disclosure remains high in the following years, the cost of equity starts to decrease.

我们的研究表明,信息互补性在透明度冲击的溢出效应中发挥着重要作用。我们利用 S&P 500 指数公司披露的财务不当行为,通过 "堆叠差分 "设计发现,相对于 "距离较远 "的行业同行,欺诈公司 "距离较近 "的行业同行的隐含资本成本会增加。当关系密切的同行与欺诈公司拥有共同的分析师覆盖范围和共同的机构所有权时,溢出效应尤为明显,而分析师覆盖范围和机构所有权已被证明是基本联系和信息互补性的有力代表。我们提供的证据表明,同行公司资本成本的增加至少部分是由于 "贝塔冲击"。在欺诈事件曝光后,关系密切的同行--尤其是那些有共同覆盖和共同所有权联系的同行--的信息披露也会增加。虽然随后几年的披露率仍然很高,但股本成本开始下降。
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引用次数: 0
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Journal of Accounting Research
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