Pub Date : 2025-08-01Epub Date: 2025-06-06DOI: 10.1016/j.cpr.2025.102611
Marie-Anne Vanderhasselt, Riet Vergauwe, Chris Baeken, Matias M. Pulopulos, Rudi De Raedt
Regulating stress effectively has a profound impact on our well-being and is known to be significantly interrelated to our social connections, as well as healthy lifestyle behaviors. However, the complex mechanisms through which these components are associated with maintaining well-being remain enigmatic.
We propose a theoretical interrelated framework for which the maintenance of brain health assumes a central role. This involves the adaptive functionality of neural circuits associated with regulating emotions, self-control, and the ability to derive pleasure from rewards or enjoyable experiences. As a result, based on brain health as a central condition, we explore how different dimensions of social connections directly impact stress regulation, or indirectly through brain health. Furthermore, we delve into how lifestyle choices indirectly affect stress regulation, mediated by their impact on brain health. Reciprocally, our lifestyle choices are wired by our social connections, reinforcing the significant role of brain health.
In the context of this conceptual framework, it is emphasized that psychotherapeutic interventions need to expand beyond the sole concentration on psychological processes. It is imperative to focus on interconnected biopsychosocial components known to positively enhance brain health, and hence to enhance the capacity of psychotherapy to significantly amplify mental health and well-being.
{"title":"Better together: The importance of brain health in the relationship between stress regulation, social connection and lifestyle in promoting mental health and well-being","authors":"Marie-Anne Vanderhasselt, Riet Vergauwe, Chris Baeken, Matias M. Pulopulos, Rudi De Raedt","doi":"10.1016/j.cpr.2025.102611","DOIUrl":"10.1016/j.cpr.2025.102611","url":null,"abstract":"<div><div>Regulating stress effectively has a profound impact on our well-being and is known to be significantly interrelated to our social connections, as well as healthy lifestyle behaviors. However, the complex mechanisms through which these components are associated with maintaining well-being remain enigmatic.</div><div>We propose a theoretical interrelated framework for which the maintenance of brain health assumes a central role. This involves the adaptive functionality of neural circuits associated with regulating emotions, self-control, and the ability to derive pleasure from rewards or enjoyable experiences. As a result, based on brain health as a central condition, we explore how different dimensions of social connections directly impact stress regulation, or indirectly through brain health. Furthermore, we delve into how lifestyle choices indirectly affect stress regulation, mediated by their impact on brain health. Reciprocally, our lifestyle choices are wired by our social connections, reinforcing the significant role of brain health.</div><div>In the context of this conceptual framework, it is emphasized that psychotherapeutic interventions need to expand beyond the sole concentration on psychological processes. It is imperative to focus on interconnected biopsychosocial components known to positively enhance brain health, and hence to enhance the capacity of psychotherapy to significantly amplify mental health and well-being.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102611"},"PeriodicalIF":13.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144272449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-05-22DOI: 10.1016/j.cpr.2025.102593
Joshua Curtiss , Christopher DiPietro
Background
Emotional disorders such as depression and anxiety affect millions globally and pose a significant burden on public health. Personalized treatment approaches using machine learning (ML) to predict treatment response could revolutionize treatment strategies. However, there is limited evidence as to whether ML is successful in predicting treatment outcomes. This meta-analysis aims to evaluate the accuracy of ML algorithms in predicting binary treatment response (responder vs. non-responder) to evidence-based psychotherapies, pharmacotherapies, and other treatments for emotional disorders, and to examine moderators of prediction accuracy.
Methods
Following PRISMA guidelines, a comprehensive literature search was conducted across PubMed and PsycINFO from January 1st, 2010 to March 27th, 2025. Studies were included if they used ML methods to predict treatment response in patients with emotional disorders. Data were extracted on sample size, type of treatment, predictors used, ML methods, and prediction accuracy. Meta-analytic techniques were used to synthesize findings and identify moderators of prediction accuracy.
Results
Out of 3816 non-duplicate records, 155 studies met inclusion criteria. The overall mean prediction accuracy was 0.76 (95 % CI: 0.74–0.78), and the mean area under the curve was 0.80 indicating good discrimination. The average sensitivity and specificity were 0.73 and 0.75, respectively. Moderator analyses indicated that studies using more robust cross-validation procedures exhibited higher prediction accuracy. Neuroimaging data as predictors were associated with higher accuracy compared to clinical and demographic data. Moreover, results indicated that studies with larger responder rates, as well as those that did not correct for imbalances in outcome rates, were associated with higher prediction accuracy.
Conclusions
ML methods show promise in predicting treatment response for emotional disorders, with varying degrees of accuracy depending on the type of predictors used and the rigor of methodological procedures implemented. Future research should focus on improving methodological integrity and exploring the integration of multimodal data to enhance prediction accuracy.
{"title":"Machine learning in the prediction of treatment response for emotional disorders: A systematic review and meta-analysis","authors":"Joshua Curtiss , Christopher DiPietro","doi":"10.1016/j.cpr.2025.102593","DOIUrl":"10.1016/j.cpr.2025.102593","url":null,"abstract":"<div><h3>Background</h3><div>Emotional disorders such as depression and anxiety affect millions globally and pose a significant burden on public health. Personalized treatment approaches using machine learning (ML) to predict treatment response could revolutionize treatment strategies. However, there is limited evidence as to whether ML is successful in predicting treatment outcomes. This meta-analysis aims to evaluate the accuracy of ML algorithms in predicting binary treatment response (responder vs. non-responder) to evidence-based psychotherapies, pharmacotherapies, and other treatments for emotional disorders, and to examine moderators of prediction accuracy.</div></div><div><h3>Methods</h3><div>Following PRISMA guidelines, a comprehensive literature search was conducted across PubMed and PsycINFO from January 1st, 2010 to March 27th, 2025. Studies were included if they used ML methods to predict treatment response in patients with emotional disorders. Data were extracted on sample size, type of treatment, predictors used, ML methods, and prediction accuracy. Meta-analytic techniques were used to synthesize findings and identify moderators of prediction accuracy.</div></div><div><h3>Results</h3><div>Out of 3816 non-duplicate records, 155 studies met inclusion criteria. The overall mean prediction accuracy was 0.76 (95 % CI: 0.74–0.78), and the mean area under the curve was 0.80 indicating good discrimination. The average sensitivity and specificity were 0.73 and 0.75, respectively. Moderator analyses indicated that studies using more robust cross-validation procedures exhibited higher prediction accuracy. Neuroimaging data as predictors were associated with higher accuracy compared to clinical and demographic data. Moreover, results indicated that studies with larger responder rates, as well as those that did not correct for imbalances in outcome rates, were associated with higher prediction accuracy.</div></div><div><h3>Conclusions</h3><div>ML methods show promise in predicting treatment response for emotional disorders, with varying degrees of accuracy depending on the type of predictors used and the rigor of methodological procedures implemented. Future research should focus on improving methodological integrity and exploring the integration of multimodal data to enhance prediction accuracy.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102593"},"PeriodicalIF":13.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The use of high-ecological validity social interactive paradigms to study social impairments in depression has burgeoned in recent 10 years. However, abnormal social behaviors in depression have exhibited substantial yet unexplained variations, ranging from reduced to increased cooperation. We proposed an attentional focus theory and introduced a novel classification of social interactive paradigms, distinguishing between responsive (attentional focus on others) and expressive (attentional focus on self) paradigms. This framework systematically elucidates the underlying reasons for reduced and increased cooperation in depression. Depression encompasses current depressive episodes, remitted depression, and subclinical depressive symptoms in undiagnosed individuals. We systematically searched Web of Science, PsycInfo, and PubMed and performed a three-level meta-analysis on 44 studies with 71 effect sizes. We found an overall significant negative association between depression and cooperation, and a significant moderation effect of the responsive versus expressive category. Depression was negatively associated with cooperation in responsive paradigms overall and in each individual responsive paradigm (Cyberball game, responder-role Ultimatum Game, Prisoner's Dilemma, and investor-role Trust Game). Depression was positively associated with cooperation in expressive paradigms overall and in the trustee-role Trust Game, and a trend of positive association in allocation tasks. In our multiple-moderator analysis, while controlling for other significant single moderators, the responsive versus expressive category remained significant, explaining 66.32 % of the total variations in effect sizes. Our study completed the half-missing landscape of social dysfunctions in social interactive paradigms in depression, which may help practitioners develop different social rehabilitation strategies tailored to responsive and expressive social scenarios.
近十年来，高生态效度社会互动范式在抑郁症社会障碍研究中的应用迅速发展。然而，抑郁症患者的异常社会行为表现出大量尚未解释的变化，从减少到增加合作。我们提出了注意焦点理论，并引入了一种新的社会互动范式分类，区分了反应性范式（注意关注他人）和表达性范式（注意关注自我）。这个框架系统地阐明了抑郁症中合作减少和增加的潜在原因。抑郁症包括当前的抑郁发作，抑郁症缓解，和亚临床抑郁症状在未确诊的个体。我们系统地检索了Web of Science、PsycInfo和PubMed，并对44项研究的71个效应量进行了三水平的荟萃分析。我们发现抑郁与合作之间存在显著的负相关，反应性与表达性之间存在显著的调节作用。在整体和个体反应范式（网络球游戏、反应者-角色最后通牒游戏、囚徒困境和投资者-角色信任游戏）中，抑郁与合作呈负相关。在整体表达范式和受托人-角色信任博弈中，抑郁与合作呈正相关，在分配任务中呈正相关趋势。在我们的多重调节因子分析中，在控制其他重要的单一调节因子的同时，反应性与表达性类别仍然显著，解释了66.32%的效应量总变化。我们的研究完成了抑郁症患者社会互动范式中社会功能障碍的半缺失景观，这可能有助于从业者制定针对反应性和表达性社会情景的不同社会康复策略。
{"title":"Cooperation patterns in depression: Insights from a meta-analysis of responsive and expressive social interactive paradigms","authors":"Yuening Jin , Ruolei Gu , Chunliang Feng , Churuo Zhang , Yuan Zhou","doi":"10.1016/j.cpr.2025.102624","DOIUrl":"10.1016/j.cpr.2025.102624","url":null,"abstract":"<div><div>The use of high-ecological validity social interactive paradigms to study social impairments in depression has burgeoned in recent 10 years. However, abnormal social behaviors in depression have exhibited substantial yet unexplained variations, ranging from reduced to increased cooperation. We proposed an attentional focus theory and introduced a novel classification of social interactive paradigms, distinguishing between responsive (attentional focus on others) and expressive (attentional focus on self) paradigms. This framework systematically elucidates the underlying reasons for reduced and increased cooperation in depression. Depression encompasses current depressive episodes, remitted depression, and subclinical depressive symptoms in undiagnosed individuals. We systematically searched Web of Science, PsycInfo, and PubMed and performed a three-level meta-analysis on 44 studies with 71 effect sizes. We found an overall significant negative association between depression and cooperation, and a significant moderation effect of the responsive versus expressive category. Depression was negatively associated with cooperation in responsive paradigms overall and in each individual responsive paradigm (Cyberball game, responder-role Ultimatum Game, Prisoner's Dilemma, and investor-role Trust Game). Depression was positively associated with cooperation in expressive paradigms overall and in the trustee-role Trust Game, and a trend of positive association in allocation tasks. In our multiple-moderator analysis, while controlling for other significant single moderators, the responsive versus expressive category remained significant, explaining 66.32 % of the total variations in effect sizes. Our study completed the half-missing landscape of social dysfunctions in social interactive paradigms in depression, which may help practitioners develop different social rehabilitation strategies tailored to responsive and expressive social scenarios.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102624"},"PeriodicalIF":12.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-06-23DOI: 10.1016/j.cpr.2025.102618
Rose Doherty , Nathan Weber , Charley Hillier , Robert Ross , Ryan Balzan
We applied a two-stage Bayesian analysis to examine the relationship between the jumping to conclusions (JTC) bias (measured on the beads, box, fishing, and/or survey tasks) and delusional ideation (measured on the Peters et al. Delusions Inventory or the Community Assessment of Psychic Experiences). MEDLINE, PsycINFO, Scopus, Web of Science, and five previous JTC reviews were searched for eligible studies published between 1988 and December 2024. Risk of bias was assessed using an adapted version of the Agency for Healthcare Research and Quality assessment tool. Forty-two studies (n = 7604) were identified as meeting inclusion criteria, with four subgroups: general population (n = 7538), psychosis with current delusions (n = 449), psychosis without current delusions (n = 29), and clinical control (n = 77). Our first analysis presented a meta-analysis of correlations between delusional ideation and JTC. Our second analysis presented a zero-inflated Poisson regression, assessing change in JTC across variable delusional ideation scores. Impact of data quality was assessed in both analyses. No meaningful relationships between JTC and delusional ideation were found in the full dataset or any subgroup, but the subgroup with current delusions showed a relatively greater JTC bias than the general population subgroup. Data-quality procedures did not impact results. Overall, results suggest that the JTC bias is not related to delusional ideation, or indexes of delusional ideation and/or JTC used in this meta-analysis are poor measures of these constructs. Our results did not assess delusional severity, thus interpretations in clinical populations are limited. PROSPERO https://www.crd.york.ac.uk/PROSPERO/view/CRD42021266402.
{"title":"Jumping to conclusions and delusional ideation: A systematic review and meta-analysis across the psychosis continuum","authors":"Rose Doherty , Nathan Weber , Charley Hillier , Robert Ross , Ryan Balzan","doi":"10.1016/j.cpr.2025.102618","DOIUrl":"10.1016/j.cpr.2025.102618","url":null,"abstract":"<div><div>We applied a two-stage Bayesian analysis to examine the relationship between the jumping to conclusions (JTC) bias (measured on the beads, box, fishing, and/or survey tasks) and delusional ideation (measured on the Peters et al. Delusions Inventory or the Community Assessment of Psychic Experiences). MEDLINE, PsycINFO, Scopus, Web of Science, and five previous JTC reviews were searched for eligible studies published between 1988 and December 2024. Risk of bias was assessed using an adapted version of the Agency for Healthcare Research and Quality assessment tool. Forty-two studies (<em>n</em> = 7604) were identified as meeting inclusion criteria, with four subgroups: general population (<em>n</em> = 7538), psychosis with current delusions (<em>n</em> = 449), psychosis without current delusions (<em>n</em> = 29), and clinical control (<em>n</em> = 77). Our first analysis presented a meta-analysis of correlations between delusional ideation and JTC. Our second analysis presented a zero-inflated Poisson regression, assessing change in JTC across variable delusional ideation scores. Impact of data quality was assessed in both analyses. No meaningful relationships between JTC and delusional ideation were found in the full dataset or any subgroup, but the subgroup with current delusions showed a relatively greater JTC bias than the general population subgroup. Data-quality procedures did not impact results. Overall, results suggest that the JTC bias is not related to delusional ideation, or indexes of delusional ideation and/or JTC used in this meta-analysis are poor measures of these constructs. Our results did not assess delusional severity, thus interpretations in clinical populations are limited. PROSPERO <span><span>https://www.crd.york.ac.uk/PROSPERO/view/CRD42021266402</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102618"},"PeriodicalIF":13.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-06-09DOI: 10.1016/j.cpr.2025.102614
Jaclyn C. Kearns , Craig P. Polizzi , Julia Naganuma-Carreras , Kyle J. Bourassa , Tate F. Halverson , Rokas Perskaudas , Nathan A. Kimbrel , Alejandro Interian , Robert M. Bossarte , Bryann B. DeBeer , Joseph I. Constans , Melissa E. Dichter , Steven K. Dobscha , Marianne Goodman , Mark Ilgen , Richard R. Owen , Brian P. Marx
Objective
There has been a proliferation of psychosocial interventions to prevent suicide over the past several decades with varying levels of benefit. We conducted a comprehensive scoping review to synthesize our knowledge of the effectiveness, strengths, and limitations of these interventions among adults. We focused on important aspects of randomized controlled trials (RCTs), including internal and external validity, outcome measurement, and exclusion criteria. We examined predictors, mediators, and moderators associated with suicide outcomes.
Methods
A systematic search was conducted for RCTs of psychosocial suicide prevention interventions with adults, following PRISMA-ScR guidelines.
Results
We identified 141 publications and 131 were unique RCTs. Publications had some concerns with risk of bias (internal validity); publications had moderate or high external validity. A quarter of RCTs excluded older adults (60 years or older) and individuals with psychotic symptoms/features and bipolar disorder/symptoms despite the fact that these groups are at elevated risk for suicide death. Forty-one publications (29.1 % of total publications) examined predictors, mediators, and moderators of suicide outcomes. Sixteen (11.3 % of total publications) publications included predictors, two (1.4 %) included mediators, 11 (7.8 %) included posttreatment mediators, and 16 (11.3 %) included moderators. Participant gender/sex, marital status, and race did not moderate treatment effects. Mixed results may be due to insufficient statistical power to test predictor, mediator, and moderator hypotheses.
Conclusion
This review highlighted RCT aspects (e.g., exclusion of older adults and individuals with serious mental illness, improving suicide outcome measurement) that may be beneficial to consider in future RCTs. Additional research on predictors, mediators, and moderators is needed.
{"title":"A scoping review of psychosocial suicide prevention interventions among adults: Clinical trial factors, predictors, mediators, and moderators in randomized controlled trials","authors":"Jaclyn C. Kearns , Craig P. Polizzi , Julia Naganuma-Carreras , Kyle J. Bourassa , Tate F. Halverson , Rokas Perskaudas , Nathan A. Kimbrel , Alejandro Interian , Robert M. Bossarte , Bryann B. DeBeer , Joseph I. Constans , Melissa E. Dichter , Steven K. Dobscha , Marianne Goodman , Mark Ilgen , Richard R. Owen , Brian P. Marx","doi":"10.1016/j.cpr.2025.102614","DOIUrl":"10.1016/j.cpr.2025.102614","url":null,"abstract":"<div><h3>Objective</h3><div>There has been a proliferation of psychosocial interventions to prevent suicide over the past several decades with varying levels of benefit. We conducted a comprehensive scoping review to synthesize our knowledge of the effectiveness, strengths, and limitations of these interventions among adults. We focused on important aspects of randomized controlled trials (RCTs), including internal and external validity, outcome measurement, and exclusion criteria. We examined predictors, mediators, and moderators associated with suicide outcomes.</div></div><div><h3>Methods</h3><div>A systematic search was conducted for RCTs of psychosocial suicide prevention interventions with adults, following PRISMA-ScR guidelines.</div></div><div><h3>Results</h3><div>We identified 141 publications and 131 were unique RCTs. Publications had some concerns with risk of bias (internal validity); publications had moderate or high external validity. A quarter of RCTs excluded older adults (60 years or older) and individuals with psychotic symptoms/features and bipolar disorder/symptoms despite the fact that these groups are at elevated risk for suicide death. Forty-one publications (29.1 % of total publications) examined predictors, mediators, and moderators of suicide outcomes. Sixteen (11.3 % of total publications) publications included predictors, two (1.4 %) included mediators, 11 (7.8 %) included posttreatment mediators, and 16 (11.3 %) included moderators. Participant gender/sex, marital status, and race did not moderate treatment effects. Mixed results may be due to insufficient statistical power to test predictor, mediator, and moderator hypotheses.</div></div><div><h3>Conclusion</h3><div>This review highlighted RCT aspects (e.g., exclusion of older adults and individuals with serious mental illness, improving suicide outcome measurement) that may be beneficial to consider in future RCTs. Additional research on predictors, mediators, and moderators is needed.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102614"},"PeriodicalIF":13.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144279048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-24DOI: 10.1016/j.cpr.2025.102626
Benedetta Tonini , Sara Bocci Benucci , Gordon Flett , Giulia Fioravanti , Silvia Casale
Introduction
The concepts of mattering and anti-mattering have garnered increasing attention in recent years, especially in relation to psychological well-being. Mattering refers to the subjective sense that one is significant to others, while anti-mattering reflects feelings of being marginalized, insignificant, and invisible with respect to others. These constructs have been linked to mental health outcomes, particularly depressive symptoms. Therefore, the aim of the present meta-analysis is to examine the association between depressive symptoms and (i) general mattering and (ii) anti-mattering.
Method
A keyword-based systematic literature search was performed for eligible studies in which general mattering/anti-mattering and depressive symptoms were assessed. The meta-analysis was conducted following the most updated PRISMA guidelines.
Results
Thirty-nine independent samples were included in quantitative analysis. Out of these, thirty-seven assessed the association between general mattering and depressive symptoms for a total of 24,397 participants (% Women = 48.09; mean age = 20.55 ± 17.24; range = 12.30–83.50) and sixteen explored the relationship between anti-mattering and depressive symptoms for a total of 9372 participants (% Women = 49.96 %; mean age = 23.62 ± 7.60; age range = 12.03–40.06). Meta-analytic results of the random effects model showed a significant negative correlation between general mattering and depressive symptoms (Fisher's Z = −0.41; CI: −0.47, −0.36; Z = 14.85; p < 0.001)) and a significant positive association between anti-mattering and depressive symptoms (Fisher's Z = 0.67; CI: 0.58, 0.76; Z = 14.95; p < 0.001). Anti-mattering exhibited a significantly stronger (positive) association with depressive symptoms compared to general mattering. Age did not moderate these associations, while gender did.
Discussion
These findings provide robust evidence for the significant relationship between both mattering and anti-mattering with depressive symptoms, also having important implications for both clinical interventions and future research.
{"title":"General Mattering, Anti-mattering, and Depressive Symptoms: A Meta-Analysis","authors":"Benedetta Tonini , Sara Bocci Benucci , Gordon Flett , Giulia Fioravanti , Silvia Casale","doi":"10.1016/j.cpr.2025.102626","DOIUrl":"10.1016/j.cpr.2025.102626","url":null,"abstract":"<div><h3>Introduction</h3><div>The concepts of mattering and anti-mattering have garnered increasing attention in recent years, especially in relation to psychological well-being. Mattering refers to the subjective sense that one is significant to others, while anti-mattering reflects feelings of being marginalized, insignificant, and invisible with respect to others. These constructs have been linked to mental health outcomes, particularly depressive symptoms. Therefore, the aim of the present meta-analysis is to examine the association between depressive symptoms and (i) general mattering and (ii) anti-mattering.</div></div><div><h3>Method</h3><div>A keyword-based systematic literature search was performed for eligible studies in which general mattering/anti-mattering and depressive symptoms were assessed. The meta-analysis was conducted following the most updated PRISMA guidelines.</div></div><div><h3>Results</h3><div>Thirty-nine independent samples were included in quantitative analysis. Out of these, thirty-seven assessed the association between general mattering and depressive symptoms for a total of 24,397 participants (% Women = 48.09; mean age = 20.55 ± 17.24; range = 12.30–83.50) and sixteen explored the relationship between anti-mattering and depressive symptoms for a total of 9372 participants (% Women = 49.96 %; mean age = 23.62 ± 7.60; age range = 12.03–40.06). Meta-analytic results of the random effects model showed a significant negative correlation between general mattering and depressive symptoms <em>(Fisher's Z =</em> −0.41; <em>CI</em>: −0.47, −0.36; <em>Z</em> = 14.85<em>; p < 0.001)</em>) and a significant positive association between anti-mattering and depressive symptoms (<em>Fisher's Z</em> = 0.67; <em>CI:</em> 0.58, 0.76; <em>Z</em> = 14.95; <em>p</em> < 0.001). Anti-mattering exhibited a significantly stronger (positive) association with depressive symptoms compared to general mattering. Age did not moderate these associations, while gender did.</div></div><div><h3>Discussion</h3><div>These findings provide robust evidence for the significant relationship between both mattering and anti-mattering with depressive symptoms, also having important implications for both clinical interventions and future research.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102626"},"PeriodicalIF":13.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-06-25DOI: 10.1016/j.cpr.2025.102619
Jennifer Kurath , Dharani Keyan , Aemal Akhtar , William Vilella Martins , Barbara Komenda , Victoria Maurer , Kadir Turgut , Richard A. Bryant , Naser Morina
Forcibly displaced people (FDP) have an elevated risk of mental disorders. Though existing interventions reduce psychological symptoms overall, many FDP do not respond, indicating a need to explore contributing factors. This systematic review examined predictors of treatment outcome among adult FDP receiving psychological and/or psychosocial interventions. Studies were included if they reported predictor analyses with positive or negative mental health outcomes. Records from five databases (MEDLINE, PsycINFO, PTSDpubs, Cochrane, Embase) and citations and bibliographies of 78 reviews, as well as of all included articles were evaluated (last update: 13.09.24). Risk of bias was assessed using Cochrane tools (RoB 2.0, ROBINS-I). Findings were synthesised using a narrative review, including a summary of effect estimates and an evaluation of evidence strength with an adapted version of the Best Evidence Synthesis Research Strategy (BESRS) framework for specialised and low-intensity interventions separately. Sixty-four studies (N = 9982, mean age = 38.0 years, 44.9 % females) reported 321 effects, of which 223 were summarised in 21 predictor categories. Most categories yielded insufficient evidence. For specialised interventions, pain, disability, lower level of education, unemployment, and longer time since arrival to the host country were associated with worse outcomes. For low-intensity interventions, a higher level of education and female gender were associated with better outcomes. Despite identifying key predictors, the high heterogeneity across studies and the large proportion of missing data warrant caution when interpreting results. Future research should ensure larger datasets and more complex models to detect consistent effects and shed light on the interplay between predictor variables. Clinicians should consider systematically assessing disability and pain at intake to provide additional support to the severely impaired.
{"title":"A systematic review on predictors of treatment outcome among forcibly displaced adults receiving psychological and/or psychosocial interventions","authors":"Jennifer Kurath , Dharani Keyan , Aemal Akhtar , William Vilella Martins , Barbara Komenda , Victoria Maurer , Kadir Turgut , Richard A. Bryant , Naser Morina","doi":"10.1016/j.cpr.2025.102619","DOIUrl":"10.1016/j.cpr.2025.102619","url":null,"abstract":"<div><div>Forcibly displaced people (FDP) have an elevated risk of mental disorders. Though existing interventions reduce psychological symptoms overall, many FDP do not respond, indicating a need to explore contributing factors. This systematic review examined predictors of treatment outcome among adult FDP receiving psychological and/or psychosocial interventions. Studies were included if they reported predictor analyses with positive or negative mental health outcomes. Records from five databases (MEDLINE, PsycINFO, PTSDpubs, Cochrane, Embase) and citations and bibliographies of 78 reviews, as well as of all included articles were evaluated (last update: 13.09.24). Risk of bias was assessed using Cochrane tools (RoB 2.0, ROBINS-I). Findings were synthesised using a narrative review, including a summary of effect estimates and an evaluation of evidence strength with an adapted version of the Best Evidence Synthesis Research Strategy (BESRS) framework for specialised and low-intensity interventions separately. Sixty-four studies (<em>N</em> = 9982, mean age = 38.0 years, 44.9 % females) reported 321 effects, of which 223 were summarised in 21 predictor categories. Most categories yielded insufficient evidence. For specialised interventions, pain, disability, lower level of education, unemployment, and longer time since arrival to the host country were associated with worse outcomes. For low-intensity interventions, a higher level of education and female gender were associated with better outcomes. Despite identifying key predictors, the high heterogeneity across studies and the large proportion of missing data warrant caution when interpreting results. Future research should ensure larger datasets and more complex models to detect consistent effects and shed light on the interplay between predictor variables. Clinicians should consider systematically assessing disability and pain at intake to provide additional support to the severely impaired.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102619"},"PeriodicalIF":13.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-07-24DOI: 10.1016/j.cpr.2025.102623
Noémie M. Cusson , Alexa J. Meilleur , Boris C. Bernhardt , Isabelle Soulières , Laurent Mottron
Empathy deficits are considered a core attribute of autism and are scored in standardized autism diagnostic instruments. However, empirical evidence concerning empathy in autism is contradictory. This systematic review, which included 226 studies, thus offers a comprehensive overview of empathy in autism. It additionally examined the impact of the chosen empathy measure and the effect of several moderators. The results reveal a large effect size for cognitive empathy (g = −0.85) and unidimensional empathy (g = −1.70), but only a small effect size for affective empathy (g = −0.17), which became non-significant when limiting analyses to high-quality studies. Meta-regressions suggest that publication year, study quality, alexithymia, verbal IQ, and age do not moderate empathy, whereas sex specifically moderates unidimensional empathy. Critically, there were notable differences in effect sizes obtained across empathy measures and even between subscales of the same measure. For instance, results for the affective empathy subscales of the Interpersonal Reactivity Index reveal lower empathic concern (g = −0.59) but increased personal distress (g = 0.67) in autistic relative to typical participants. A qualitative review of ecological and neuroimaging tasks mostly demonstrated minimal autistic versus non-autistic differences. This meta-analysis thus suggests that measuring empathy as a unidimensional construct may both distort and increase the notion of an empathy deficit in autism.
{"title":"A systematic review and meta-analysis of empathy in autism: The influence of measures","authors":"Noémie M. Cusson , Alexa J. Meilleur , Boris C. Bernhardt , Isabelle Soulières , Laurent Mottron","doi":"10.1016/j.cpr.2025.102623","DOIUrl":"10.1016/j.cpr.2025.102623","url":null,"abstract":"<div><div>Empathy deficits are considered a core attribute of autism and are scored in standardized autism diagnostic instruments. However, empirical evidence concerning empathy in autism is contradictory. This systematic review, which included 226 studies, thus offers a comprehensive overview of empathy in autism. It additionally examined the impact of the chosen empathy measure and the effect of several moderators. The results reveal a large effect size for cognitive empathy (<em>g</em> = −0.85) and unidimensional empathy (<em>g</em> = −1.70), but only a small effect size for affective empathy (<em>g</em> = −0.17), which became non-significant when limiting analyses to high-quality studies. Meta-regressions suggest that publication year, study quality, alexithymia, verbal IQ, and age do not moderate empathy, whereas sex specifically moderates unidimensional empathy. Critically, there were notable differences in effect sizes obtained across empathy measures and even between subscales of the same measure. For instance, results for the affective empathy subscales of the Interpersonal Reactivity Index reveal lower empathic concern (<em>g</em> = −0.59) but increased personal distress (<em>g</em> = 0.67) in autistic relative to typical participants. A qualitative review of ecological and neuroimaging tasks mostly demonstrated minimal autistic versus non-autistic differences. This meta-analysis thus suggests that measuring empathy as a unidimensional construct may both distort and increase the notion of an empathy deficit in autism.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102623"},"PeriodicalIF":12.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-06-19DOI: 10.1016/j.cpr.2025.102617
Maria Jernslett , Ryan P. Kilmer , Demetris Avraam , Xenia Anastassiou-Hadjicharalambous
Trauma may engender both posttraumatic stress symptoms (PTSS) and posttraumatic growth (PTG) among youth, but what is the nature of the relationship between these variables and what does it imply about youths' recovery trajectories? To explore this, PubMed, PsycINFO, Scopus, ERIC, and ProQuest Dissertations and Theses Global were searched, supplemented by reference trails, journal searches, and expert consultations, to identify quantitative studies on PTSS and PTG in youth (mean age ≤ 19 years). This resulted in 63 eligible articles. Both linear (n = 53) and curvilinear (n = 12) estimates were meta-analysed using random-effects models. Linear dependent estimates were pooled using weighted corrected averages and curvilinear dependent effects were clustered using robust variance estimation. The pooled linear estimate was r = 0.2028 [95 % CI 0.1348; 0.2689], p < .0001, based on 53 independent estimates and a total sample size of 33,774.6. The pooled curvilinear estimate was b = −0.199 (SE = 0.0573, p = .012). Moderator analyses further revealed a significant cultural influence, with Western youth (r = 0.3100 [95 % CI 0.1977; 0.4142], N = 6141) demonstrating a stronger association between PTSS and PTG compared to their Eastern counterparts (r = 0.0727 [95 % CI −0.0130; 0.1574], N = 21,778.42). The findings paint a nuanced and complex picture of posttrauma responses among youth, ultimately underscoring that, while PTSS and PTG can coexist, PTSS that are too excessive may not be conducive to PTG.
创伤可能在青少年中产生创伤后应激症状（PTSS）和创伤后成长（PTG），但这些变量之间的关系的本质是什么？它对青少年的恢复轨迹意味着什么？为此，我们检索了PubMed、PsycINFO、Scopus、ERIC和ProQuest dissertation and Theses Global，并辅以参考文献、期刊检索和专家咨询，以确定青少年（平均年龄 ≤ 19 岁）中PTSS和PTG的定量研究。这产生了63个符合条件的条目。使用随机效应模型对线性（n = 53）和曲线（n = 12）估计值进行meta分析。线性相关估计使用加权校正平均值进行汇总，曲线相关效应使用稳健方差估计进行聚类。合并线性估计r = 0.2028[95 % CI 0.1348；0.2689], p & lt; 。0001，基于53个独立估计，总样本量为33,774.6。合并曲线估计值为b = −0.199 （SE = 0.0573,p = 0.012）。调节因子分析进一步揭示了显著的文化影响，西方青年(r = 0.3100[95 % CI 0.1977；0.4142], N = 6141)，表明PTSS和PTG之间的相关性强于东部地区(r = 0.0727[95 % CI−0.0130；0.1574), N = 21778点)。研究结果描绘了年轻人创伤后反应的微妙而复杂的图景，最终强调，虽然创伤后应激障碍和创伤后应激障碍可以共存，但过度的创伤后应激障碍可能不利于创伤后应激障碍。
{"title":"Growing through adversity: A meta-analytic and conceptual elucidation of the relationship between posttraumatic stress and posttraumatic growth among youth","authors":"Maria Jernslett , Ryan P. Kilmer , Demetris Avraam , Xenia Anastassiou-Hadjicharalambous","doi":"10.1016/j.cpr.2025.102617","DOIUrl":"10.1016/j.cpr.2025.102617","url":null,"abstract":"<div><div>Trauma may engender both posttraumatic stress symptoms (PTSS) and posttraumatic growth (PTG) among youth, but what is the nature of the relationship between these variables and what does it imply about youths' recovery trajectories? To explore this, PubMed, PsycINFO, Scopus, ERIC, and ProQuest Dissertations and Theses Global were searched, supplemented by reference trails, journal searches, and expert consultations, to identify quantitative studies on PTSS and PTG in youth (mean age ≤ 19 years). This resulted in 63 eligible articles. Both linear (<em>n</em> = 53) and curvilinear (<em>n</em> = 12) estimates were meta-analysed using random-effects models. Linear dependent estimates were pooled using weighted corrected averages and curvilinear dependent effects were clustered using robust variance estimation. The pooled linear estimate was <em>r</em> = 0.2028 [95 % CI 0.1348; 0.2689], <em>p</em> < .0001, based on 53 independent estimates and a total sample size of 33,774.6. The pooled curvilinear estimate was <em>b</em> = −0.199 (<em>SE</em> = 0.0573, <em>p</em> = .012). Moderator analyses further revealed a significant cultural influence, with Western youth (<em>r</em> = 0.3100 [95 % CI 0.1977; 0.4142], <em>N</em> = 6141) demonstrating a stronger association between PTSS and PTG compared to their Eastern counterparts (<em>r</em> = 0.0727 [95 % CI −0.0130; 0.1574], <em>N</em> = 21,778.42). The findings paint a nuanced and complex picture of posttrauma responses among youth, ultimately underscoring that, while PTSS and PTG can coexist, PTSS that are too excessive may not be conducive to PTG.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102617"},"PeriodicalIF":13.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-01Epub Date: 2025-06-23DOI: 10.1016/j.cpr.2025.102615
Heba Elgharbawy , Carrie Bove
Stepping into a counselling office can be rife with barriers and inherent challenges, particularly for Indigenous communities who experience structural forms of marginalization or colonial violence or oppression. Outreach counselling, which is an alternative to traditional, often Eurocentric, office-based counselling services, can serve as a flexible, personal, cultural, and community-centered support. There is currently a scarcity of research that explores outreach counselling and its impacts on client engagement and wellness, specifically from Indigenous youth voices. This project involved a literature review of the available information on outreach counselling use with Indigenous communities across the globe. Through thematic analysis, four main themes were identified including 1) a lack of evidence on outreach service models and research evaluating its use with Indigenous communities and particularly with Indigenous youth, 2) evidence that suggests a strong call for more outreach counselling as it increases accessibility, 3) improved wellness through outreach models, and 4) considerations for practitioners when implementing outreach models in counselling. Actionable recommendations to enhance the accessibility and sustainability of outreach counselling services with Indigenous youth and families and ethical considerations are discussed. These findings offer communities and mental health professionals an overview of an alternative counselling model that can provide a more tailored approach to clinical care for Indigenous youth.
{"title":"Beyond the office: The role of clinical outreach services in counselling with Indigenous youth and families","authors":"Heba Elgharbawy , Carrie Bove","doi":"10.1016/j.cpr.2025.102615","DOIUrl":"10.1016/j.cpr.2025.102615","url":null,"abstract":"<div><div>Stepping into a counselling office can be rife with barriers and inherent challenges, particularly for Indigenous communities who experience structural forms of marginalization or colonial violence or oppression. Outreach counselling, which is an alternative to traditional, often Eurocentric, office-based counselling services, can serve as a flexible, personal, cultural, and community-centered support. There is currently a scarcity of research that explores outreach counselling and its impacts on client engagement and wellness, specifically from Indigenous youth voices. This project involved a literature review of the available information on outreach counselling use with Indigenous communities across the globe. Through thematic analysis, four main themes were identified including 1) a lack of evidence on outreach service models and research evaluating its use with Indigenous communities and particularly with Indigenous youth, 2) evidence that suggests a strong call for more outreach counselling as it increases accessibility, 3) improved wellness through outreach models, and 4) considerations for practitioners when implementing outreach models in counselling. Actionable recommendations to enhance the accessibility and sustainability of outreach counselling services with Indigenous youth and families and ethical considerations are discussed. These findings offer communities and mental health professionals an overview of an alternative counselling model that can provide a more tailored approach to clinical care for Indigenous youth.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"120 ","pages":"Article 102615"},"PeriodicalIF":13.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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