Childhood trauma has been consistently associated with elevated levels of neuroticism in adulthood, a transdiagnostic trait marked by emotional instability, heightened negative affect, and stress sensitivity. This systematic review and meta-analysis aimed to synthesise evidence examining the association between childhood trauma and adult neuroticism, both overall and by specific trauma subtypes. A comprehensive search of four electronic databases identified 136 eligible studies, encompassing a total of 526,371 individuals. Using a random-effects meta-analysis, results revealed a significant positive association between childhood trauma and adult neuroticism (g = 0.46). The strength of the association between neuroticism and the different trauma subtype varied. The strongest association was observed for emotional neglect (g = 0.40), followed by emotional abuse (g = 0.33). In addition, there were associations between neuroticism and physical abuse (g = 0.18), physical neglect (g = 0.15), sexual abuse (g = 0.22), unspecified abuse (g = 0.13), and victimisation (g = 0.21), with the exception of unspecified neglect, which showed no significant association. These findings demonstrate a robust relationship between early adversity and neuroticism. Childhood trauma may lead to adaptions that give rise to neuroticism through several psychological mechanisms such as disruptions in attachment and the formation of negative self-beliefs, and neurobiological alterations in stress regulation systems. These results underscore the importance of systemic preventative measures and early intervention strategies that may alleviate the psychological and neurobiological consequences of trauma, with the potential to increase awareness of adaptions such as neuroticism in trauma-exposed populations.
童年创伤一直与成年后神经质水平升高有关,这是一种以情绪不稳定、负面情绪加剧和压力敏感性为特征的跨诊断特征。本系统综述和荟萃分析旨在综合证据,研究儿童创伤和成人神经质之间的联系,包括总体和特定的创伤亚型。对四个电子数据库的全面搜索确定了136项符合条件的研究,共涉及526,371人。采用随机效应荟萃分析,结果显示儿童创伤与成人神经质之间存在显著的正相关(g = 0.46)。神经质与不同创伤亚型之间的关联强度各不相同。最强的关联是情绪忽视(g = 0.40),其次是情绪虐待(g = 0.33)。此外,还有神经质和身体虐待之间的关联(0.18 g = ),物理忽视(0.15 g = ),性虐待(0.22 g = ),未指明的滥用(0.13 g = ),和受害(0.21 g = ),除了未指明的忽视,显示无显著关联。这些发现证明了早期逆境和神经质之间的紧密联系。童年创伤可能通过一些心理机制导致适应,如依恋的中断和消极自我信念的形成,以及压力调节系统的神经生物学改变,从而产生神经质。这些结果强调了系统预防措施和早期干预策略的重要性,这些措施可能会减轻创伤的心理和神经生物学后果,并有可能提高创伤暴露人群对神经质等适应的认识。
{"title":"The relationship between childhood trauma and adult neuroticism: A systematic review and meta-analysis","authors":"Norma Rosenek, Shannon Wake, Rachel Runton, Amber Davies, Nur Albaroudi, Abigail Pollen, Lyn Ellett, Jayne Morriss","doi":"10.1016/j.cpr.2026.102700","DOIUrl":"https://doi.org/10.1016/j.cpr.2026.102700","url":null,"abstract":"Childhood trauma has been consistently associated with elevated levels of neuroticism in adulthood, a transdiagnostic trait marked by emotional instability, heightened negative affect, and stress sensitivity. This systematic review and meta-analysis aimed to synthesise evidence examining the association between childhood trauma and adult neuroticism, both overall and by specific trauma subtypes. A comprehensive search of four electronic databases identified 136 eligible studies, encompassing a total of 526,371 individuals. Using a random-effects meta-analysis, results revealed a significant positive association between childhood trauma and adult neuroticism (<ce:italic>g</ce:italic> = 0.46). The strength of the association between neuroticism and the different trauma subtype varied. The strongest association was observed for emotional neglect (<ce:italic>g</ce:italic> = 0.40), followed by emotional abuse (<ce:italic>g</ce:italic> = 0.33). In addition, there were associations between neuroticism and physical abuse (<ce:italic>g</ce:italic> = 0.18), physical neglect (<ce:italic>g</ce:italic> = 0.15), sexual abuse (<ce:italic>g</ce:italic> = 0.22), unspecified abuse (<ce:italic>g</ce:italic> = 0.13), and victimisation (<ce:italic>g</ce:italic> = 0.21), with the exception of unspecified neglect, which showed no significant association. These findings demonstrate a robust relationship between early adversity and neuroticism. Childhood trauma may lead to adaptions that give rise to neuroticism through several psychological mechanisms such as disruptions in attachment and the formation of negative self-beliefs, and neurobiological alterations in stress regulation systems. These results underscore the importance of systemic preventative measures and early intervention strategies that may alleviate the psychological and neurobiological consequences of trauma, with the potential to increase awareness of adaptions such as neuroticism in trauma-exposed populations.","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"29 1","pages":""},"PeriodicalIF":12.8,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-07DOI: 10.1016/j.cpr.2026.102693
Liucan Xu , Simon B. Goldberg , Lin Zhang , Chuyu Hu
Background
Second-generation mindfulness-based interventions (SG-MBIs), which integrate ethical and moral practices, have emerged as promising treatments for depressive and anxiety symptoms. This meta-analysis aims to evaluate the effectiveness of SG-MBIs in reducing depression and anxiety among adults.
Methods
We conducted a meta-analysis of randomized controlled trials (RCTs) including adults from clinical populations, healthy adults, and mixed groups (e.g., individuals reporting psychological distress or physical health conditions without formal diagnoses). Databases searched included PubMed, Web of Science, and EBSCOhost (through April 2025). Effect sizes were computed using Hedges' g, calculated as the standardized mean differences between intervention and control groups at post-intervention, adjusted for small-sample bias, and synthesized under a random-effects model. Primary analyses focused on post-intervention outcomes, and additional analyses assessed long-term effects based on follow-up data from 20 trials (17 depression, 13 anxiety). In total, 43 studies on depression (n = 3756) and 37 studies on anxiety (n = 3199) were included. Moderator analyses tested participant type, control condition, intervention components, intervention type, primary outcome status and risk of bias status.
Results
SG-MBIs significantly reduced depressive (g = 0.59, 95 % CI [0.41, 0.78]) and anxiety symptoms (g = 0.61, 95 % CI [0.41, 0.81]); effects remained significant after outlier removal (depression: g = 0.44; anxiety: g = 0.40). Participant type significantly moderated outcomes, with clinical samples showing significantly larger improvements than both healthy and mixed samples. Intervention type also significantly moderated results. Control conditions, intervention components, outcome measures, primary outcome status, risk of bias status, and intervention duration were not significant moderators. Follow-up data (k = 20) indicated sustained depression reductions (g = 0.70). Most included trials were rated as having “some concerns” (n = 33), with 13 judged as low risk and 3 as high risk, suggesting that overall findings should be interpreted with caution. However, sensitivity analyses excluding these high-risk studies yielded similar results (depression: g = 0.61; anxiety: g = 0.64).
Conclusions
SG-MBIs effectively reduce depression and anxiety and may be particularly valuable for clinical populations and self-compassion–focused interventions. Future research should aim for clearer operational definitions, standardized intervention protocols, exploration of wisdom-based components, and adequately powered RCTs to strengthen the evidence base and enhance clinical applicability.
{"title":"The effectiveness of second-generation mindfulness interventions on anxiety and depression: A systematic review and meta-analysis","authors":"Liucan Xu , Simon B. Goldberg , Lin Zhang , Chuyu Hu","doi":"10.1016/j.cpr.2026.102693","DOIUrl":"10.1016/j.cpr.2026.102693","url":null,"abstract":"<div><h3>Background</h3><div>Second-generation mindfulness-based interventions (SG-MBIs), which integrate ethical and moral practices, have emerged as promising treatments for depressive and anxiety symptoms. This meta-analysis aims to evaluate the effectiveness of SG-MBIs in reducing depression and anxiety among adults.</div></div><div><h3>Methods</h3><div>We conducted a meta-analysis of randomized controlled trials (RCTs) including adults from clinical populations, healthy adults, and mixed groups (e.g., individuals reporting psychological distress or physical health conditions without formal diagnoses). Databases searched included PubMed, Web of Science, and EBSCOhost (through April 2025). Effect sizes were computed using Hedges' g, calculated as the standardized mean differences between intervention and control groups at post-intervention, adjusted for small-sample bias, and synthesized under a random-effects model. Primary analyses focused on post-intervention outcomes, and additional analyses assessed long-term effects based on follow-up data from 20 trials (17 depression, 13 anxiety). In total, 43 studies on depression (<em>n</em> = 3756) and 37 studies on anxiety (<em>n</em> = 3199) were included. Moderator analyses tested participant type, control condition, intervention components, intervention type, primary outcome status and risk of bias status.</div></div><div><h3>Results</h3><div>SG-MBIs significantly reduced depressive (g = 0.59, 95 % CI [0.41, 0.78]) and anxiety symptoms (g = 0.61, 95 % CI [0.41, 0.81]); effects remained significant after outlier removal (depression: g = 0.44; anxiety: g = 0.40). Participant type significantly moderated outcomes, with clinical samples showing significantly larger improvements than both healthy and mixed samples. Intervention type also significantly moderated results. Control conditions, intervention components, outcome measures, primary outcome status, risk of bias status, and intervention duration were not significant moderators. Follow-up data (k = 20) indicated sustained depression reductions (g = 0.70). Most included trials were rated as having “some concerns” (<em>n</em> = 33), with 13 judged as low risk and 3 as high risk, suggesting that overall findings should be interpreted with caution. However, sensitivity analyses excluding these high-risk studies yielded similar results (depression: g = 0.61; anxiety: g = 0.64).</div></div><div><h3>Conclusions</h3><div>SG-MBIs effectively reduce depression and anxiety and may be particularly valuable for clinical populations and self-compassion–focused interventions. Future research should aim for clearer operational definitions, standardized intervention protocols, exploration of wisdom-based components, and adequately powered RCTs to strengthen the evidence base and enhance clinical applicability.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"123 ","pages":"Article 102693"},"PeriodicalIF":12.2,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-06DOI: 10.1016/j.cpr.2026.102692
Ausiàs Cebolla , Belén Fernández-Castilla , Oscar Lecuona , Jéssica Navarro-Siurana , Julieta Galante , Pedro Sarrión , Joana Vidal , Rosa M. Baños , Carmelo Vázquez
Mental health research emphasizes the importance of fostering character strengths to promote well-being. However, whether the strengths supposedly developed by these interventions actually mediate their effects on well-being is still unknown. The included studies were RCTs of strength-based interventions on well-being. Among 83,908 reviewed abstracts, five strengths met the strict inclusion criteria to be meta-analyzed. We included 114 RCTs with a total of 20,853 participants. A One-Stage Meta-Analytic Structural Equation Modeling approach was used to combine studies and analyze the mediation models. Perspective-based interventions showed improvements in perspective. Kindness-based interventions and gratitude-based interventions demonstrated moderate associations with their respective strengths. Humor and hope-based interventions did not significantly enhance their respective trained strengths. Significant mediation effects on well-being were found for all strengths, except hope. The robust pattern of mediations aligns with eudaemonic theories, emphasizing the importance of virtue-driven actions in fostering psychological well-being.
{"title":"Efficacy of cultivating human strengths and virtues on well-being: A one-stage meta-analytic structural equation modeling approach","authors":"Ausiàs Cebolla , Belén Fernández-Castilla , Oscar Lecuona , Jéssica Navarro-Siurana , Julieta Galante , Pedro Sarrión , Joana Vidal , Rosa M. Baños , Carmelo Vázquez","doi":"10.1016/j.cpr.2026.102692","DOIUrl":"10.1016/j.cpr.2026.102692","url":null,"abstract":"<div><div>Mental health research emphasizes the importance of fostering character strengths to promote well-being. However, whether the strengths supposedly developed by these interventions actually mediate their effects on well-being is still unknown. The included studies were RCTs of strength-based interventions on well-being. Among 83,908 reviewed abstracts, five strengths met the strict inclusion criteria to be meta-analyzed. We included 114 RCTs with a total of 20,853 participants. A One-Stage Meta-Analytic Structural Equation Modeling approach was used to combine studies and analyze the mediation models. Perspective-based interventions showed improvements in perspective. Kindness-based interventions and gratitude-based interventions demonstrated moderate associations with their respective strengths. Humor and hope-based interventions did not significantly enhance their respective trained strengths. Significant mediation effects on well-being were found for all strengths, except hope. The robust pattern of mediations aligns with eudaemonic theories, emphasizing the importance of virtue-driven actions in fostering psychological well-being.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"124 ","pages":"Article 102692"},"PeriodicalIF":12.2,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-22DOI: 10.1016/j.cpr.2025.102691
Hannah G. Swerbenski , Justin Russotti
Attachment-based Interventions (ABIs) refer to treatments that leverage tenets of Attachment Theory in clinical work with caregivers and children. Integrating Attachment Theory and developmental psychopathology frameworks, this meta-analysis reports the efficacy of ABIs for reducing both caregiver and child psychopathology. We screened studies from PsycInfo, PubMed, and Web of Science, identifying 70 unique studies (Ntotal = 6645 families) that met inclusion criteria. We report 19 meta-analytic effects (8 for caregivers, 11 for children). We observed large Pre-Post effects of ABIs on changes in caregiver posttraumatic stress (d = −0.986), caregiver depression at later follow-up (d = −0.828), child posttraumatic stress (d = −0.744) and child total problems both at post-treatment (d = − 0.728) and follow-up (d = −1.143). We observed medium Pre-Post effects of ABIs on caregiver depression (d = −0.623), global distress (d = −0.621), anxiety (d = −0.553), and child internalizing (d = −0.485), as well as medium RCT effects of ABIs on changes in caregiver global distress (d = −0.408) and depression at follow-up (d = −0.588). We found small RCT effects for for caregiver depression, child internalizing, externalizing, and total problems, as well as child internalizing, externalizing, and total problems at later follow-up (ds = −0.355 to −0.066). Ten studies (Noverlap = 795) that met both caregiver and child inclusion criteria were included in exploratory dyadic analyses which revealed reductions in caregiver and child psychopathology were significantly correlated (r = 0.480, p < .001). Results underscore benefits of ABIs for broader treatment targets beyond attachment security.
{"title":"Dyadic approaches to treating individual functioning: A review and dual meta-analysis of the effects of attachment-based interventions on caregiver and child psychopathology","authors":"Hannah G. Swerbenski , Justin Russotti","doi":"10.1016/j.cpr.2025.102691","DOIUrl":"10.1016/j.cpr.2025.102691","url":null,"abstract":"<div><div>Attachment-based Interventions (ABIs) refer to treatments that leverage tenets of Attachment Theory in clinical work with caregivers and children. Integrating Attachment Theory and developmental psychopathology frameworks, this meta-analysis reports the efficacy of ABIs for reducing <em>both</em> caregiver and child psychopathology. We screened studies from <em>PsycInfo, PubMed,</em> and <em>Web of Science,</em> identifying 70 unique studies (<em>N</em><sub><em>total</em></sub> = 6645 families) that met inclusion criteria<em>.</em> We report 19 meta-analytic effects (8 for caregivers, 11 for children). We observed large Pre-Post effects of ABIs on changes in caregiver posttraumatic stress (<em>d</em> = −0.986), caregiver depression at later follow-up (<em>d</em> = −0.828), child posttraumatic stress (<em>d</em> = −0.744) and child total problems both at post-treatment (<em>d</em> = − 0.728) and follow-up (<em>d</em> = −1.143). We observed medium Pre-Post effects of ABIs on caregiver depression (<em>d</em> = −0.623), global distress (<em>d</em> = −0.621), anxiety (<em>d</em> = −0.553), and child internalizing (<em>d</em> = −0.485), as well as medium RCT effects of ABIs on changes in caregiver global distress (<em>d</em> = −0.408) and depression at follow-up (<em>d</em> = −0.588). We found small RCT effects for for caregiver depression, child internalizing, externalizing, and total problems, as well as child internalizing, externalizing, and total problems at later follow-up (<em>d</em>s = −0.355 to −0.066). Ten studies (<em>N</em><sub><em>overlap</em></sub> = 795) that met both caregiver and child inclusion criteria were included in exploratory dyadic analyses which revealed reductions in caregiver and child psychopathology were significantly correlated (<em>r</em> = 0.480, <em>p</em> < .001). Results underscore benefits of ABIs for broader treatment targets beyond attachment security.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"123 ","pages":"Article 102691"},"PeriodicalIF":12.2,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11DOI: 10.1016/j.cpr.2025.102689
Igor Marchetti , Ernst H.W. Koster , Jan Dul
Understanding the causal mechanisms underlying the development of mental disorders and their symptoms is essential for advancing effective prevention and treatment strategies. However, research in this field has predominantly relied on sufficiency logic within a probabilistic framework, coupled with traditional statistical methods (i.e., multiple linear regression, Structural Equation Modelling, etc.) where risk factors are associated with an increased likelihood of developing a disorder. While valuable, this approach also carries inherent assumptions and limitations. Additionally, the crucial concept of causal necessity has been largely overlooked. By integrating necessity logic within a deterministic framework—where the absence of a necessary risk factor prevents the development of a disorder in nearly everyone— we propose a novel and promising approach, exemplified by Necessary Condition Analysis (NCA). In this paper, we outline the theoretical foundations of NCA and illustrate its potential for advancing mental health research, with a specific application to the Interpersonal Theory of Suicide. We also discuss how NCA can address critical challenges in mental health science, refine existing methodologies, and open new pathways for enhancing both research and clinical practice.
{"title":"Necessity causality in mental health research: Applying necessary condition analysis in clinical psychology and psychiatry","authors":"Igor Marchetti , Ernst H.W. Koster , Jan Dul","doi":"10.1016/j.cpr.2025.102689","DOIUrl":"10.1016/j.cpr.2025.102689","url":null,"abstract":"<div><div>Understanding the causal mechanisms underlying the development of mental disorders and their symptoms is essential for advancing effective prevention and treatment strategies. However, research in this field has predominantly relied on <em>sufficiency logic</em> within a probabilistic framework, coupled with traditional statistical methods (i.e., multiple linear regression, Structural Equation Modelling, etc.) where risk factors are associated with an increased likelihood of developing a disorder. While valuable, this approach also carries inherent assumptions and limitations. Additionally, the crucial concept of causal necessity has been largely overlooked. By integrating <em>necessity logic</em> within a deterministic framework—where the absence of a necessary risk factor prevents the development of a disorder in nearly everyone— we propose a novel and promising approach, exemplified by Necessary Condition Analysis (NCA). In this paper, we outline the theoretical foundations of NCA and illustrate its potential for advancing mental health research, with a specific application to the Interpersonal Theory of Suicide. We also discuss how NCA can address critical challenges in mental health science, refine existing methodologies, and open new pathways for enhancing both research and clinical practice.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"123 ","pages":"Article 102689"},"PeriodicalIF":12.2,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145730896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-11DOI: 10.1016/j.cpr.2025.102690
Frederica M. Martijn , Nicholas Blagden , Thom Baguley , Elisabeth J. Leroux , Jennifer Mackay , Michael C. Seto
There are important scientific gaps in the understanding of the role of familial dysfunction in intrafamilial child sexual abuse perpetration and victimisation. We present the findings of a systematic review and a comparative (k = 18) and prevalence (k = 39) meta-analysis of intrafamilial child sexual abuse and familial dysfunction. We compared 3676 families in which intrafamilial child sexual abuse had occurred with 1120 families in which extrafamilial and 1145 families in which no (intrafamilial) child sexual abuse had occurred. We found that families with intrafamilial child sexual abuse experienced more familial dysfunction across all domains compared to comparison families, with odds ratios ranging from 1.10 (lower educational attainment) to 5.06 (parental alcohol abuse). Families with intrafamilial child sexual abuse experienced more socio-ecological stressors (e.g., homelessness), disorganised family structures (e.g., non-intact parental structures), dysfunctional relationships (e.g., spousal conflict), nonsexual abuse (e.g., exposure to intimate partner violence), and parental vulnerabilities (e.g., mental health and substance abuse problems) than the comparison families. The prevalence meta-analysis indicated that almost half of the families with intrafamilial child sexual abuse also experienced one or more co-occurring forms of nonsexual abuse – 48 % physical abuse, 37 % emotional abuse, 34 % neglect, and 42 % exposure to intimate partner violence – and that this was significantly higher than the comparison families. The results of this meta-analysis highlight gaps and directions for further research on the role of familial dysfunction in intrafamilial child sexual abuse, and the aetiology and prognosis of polyvictimisation.
{"title":"What about the family in intrafamilial child sexual abuse? There is significantly more familial dysfunction in families with intrafamilial child sexual abuse than in other families","authors":"Frederica M. Martijn , Nicholas Blagden , Thom Baguley , Elisabeth J. Leroux , Jennifer Mackay , Michael C. Seto","doi":"10.1016/j.cpr.2025.102690","DOIUrl":"10.1016/j.cpr.2025.102690","url":null,"abstract":"<div><div>There are important scientific gaps in the understanding of the role of familial dysfunction in intrafamilial child sexual abuse perpetration and victimisation. We present the findings of a systematic review and a comparative (<em>k</em> = 18) and prevalence (<em>k</em> = 39) meta-analysis of intrafamilial child sexual abuse and familial dysfunction. We compared 3676 families in which intrafamilial child sexual abuse had occurred with 1120 families in which extrafamilial and 1145 families in which no (intrafamilial) child sexual abuse had occurred. We found that families with intrafamilial child sexual abuse experienced more familial dysfunction across all domains compared to comparison families, with odds ratios ranging from 1.10 (lower educational attainment) to 5.06 (parental alcohol abuse). Families with intrafamilial child sexual abuse experienced more socio-ecological stressors (e.g., homelessness), disorganised family structures (e.g., non-intact parental structures), dysfunctional relationships (e.g., spousal conflict), nonsexual abuse (e.g., exposure to intimate partner violence), and parental vulnerabilities (e.g., mental health and substance abuse problems) than the comparison families. The prevalence meta-analysis indicated that almost half of the families with intrafamilial child sexual abuse also experienced one or more co-occurring forms of nonsexual abuse – 48 % physical abuse, 37 % emotional abuse, 34 % neglect, and 42 % exposure to intimate partner violence – and that this was significantly higher than the comparison families. The results of this meta-analysis highlight gaps and directions for further research on the role of familial dysfunction in intrafamilial child sexual abuse, and the aetiology and prognosis of polyvictimisation.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"123 ","pages":"Article 102690"},"PeriodicalIF":12.2,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145730895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-09DOI: 10.1016/j.cpr.2025.102688
Ari Alex Ramos , Vinícius Boaventura , Alanis Aparecida Nascimento , Luana Lopes Rocha Leite , Liana Machado
Background
Emerging literature suggests that neurocognitive traits commonly observed in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) are present, albeit to a lesser degree, in their non-ADHD siblings. This meta-analytic review aimed to quantitatively summarize intellectual and cognitive performance differences between children and adolescents without ADHD and both their ADHD-diagnosed siblings and unrelated peers without ADHD.
Methods
We implemented strategic search algorithms in four indexing databases (PubMed/MEDLINE, Web of Science, PsycINFO, and ProQuest) to retrieve potentially eligible reports published up to 5th June 2025. Meta-analyses were conducted using three-level hierarchical models to account for the dependency among effect sizes derived from the same study. Between-group differences in intellectual and cognitive scores were quantified using standardized mean differences (SMD). Moreover, we assessed the robustness of the findings by testing for potential small-study effects.
Results
Based on 404 unique effect sizes derived from 32 studies, involving a total of 8873 participants, the current results demonstrate that the overall cognitive-intellectual performance of siblings surpasses their ADHD-affected siblings (SMD = 0.30, 95 % CI [0.23, 0.38]), but falls short of unrelated peers (SMD = −0.28, 95 % CI [−0.35, −0.21]). This suggests that non-ADHD siblings exhibit an intermediate neurocognitive profile between their ADHD-affected siblings and peers without ADHD. Notably, we observed this pattern of results consistently across the major cognitive categories examined (intellectual functioning, attention and perceptual-temporal processing, memory, and executive functions). Importantly, no evidence of small-study effects was found.
Conclusion
The current findings provide robust support for cognitive-intellectual vulnerabilities in siblings of ADHD-diagnosed children and adolescents, possibly accounted for by genetic inheritance, shared environmental influences, and gene-environment interactions.
{"title":"Intellectual achievement and cognitive functioning in children and adolescents with ADHD-affected siblings: A systematic literature review and meta-analysis","authors":"Ari Alex Ramos , Vinícius Boaventura , Alanis Aparecida Nascimento , Luana Lopes Rocha Leite , Liana Machado","doi":"10.1016/j.cpr.2025.102688","DOIUrl":"10.1016/j.cpr.2025.102688","url":null,"abstract":"<div><h3>Background</h3><div>Emerging literature suggests that neurocognitive traits commonly observed in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) are present, albeit to a lesser degree, in their non-ADHD siblings. This meta-analytic review aimed to quantitatively summarize intellectual and cognitive performance differences between children and adolescents without ADHD and both their ADHD-diagnosed siblings and unrelated peers without ADHD.</div></div><div><h3>Methods</h3><div>We implemented strategic search algorithms in four indexing databases (PubMed/MEDLINE, Web of Science, PsycINFO, and ProQuest) to retrieve potentially eligible reports published up to 5<sup>th</sup> June 2025. Meta-analyses were conducted using three-level hierarchical models to account for the dependency among effect sizes derived from the same study. Between-group differences in intellectual and cognitive scores were quantified using standardized mean differences (SMD). Moreover, we assessed the robustness of the findings by testing for potential small-study effects.</div></div><div><h3>Results</h3><div>Based on 404 unique effect sizes derived from 32 studies, involving a total of 8873 participants, the current results demonstrate that the overall cognitive-intellectual performance of siblings surpasses their ADHD-affected siblings (SMD = 0.30, 95 % CI [0.23, 0.38]), but falls short of unrelated peers (SMD = −0.28, 95 % CI [−0.35, −0.21]). This suggests that non-ADHD siblings exhibit an intermediate neurocognitive profile between their ADHD-affected siblings and peers without ADHD. Notably, we observed this pattern of results consistently across the major cognitive categories examined (intellectual functioning, attention and perceptual-temporal processing, memory, and executive functions). Importantly, no evidence of small-study effects was found.</div></div><div><h3>Conclusion</h3><div>The current findings provide robust support for cognitive-intellectual vulnerabilities in siblings of ADHD-diagnosed children and adolescents, possibly accounted for by genetic inheritance, shared environmental influences, and gene-environment interactions.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"123 ","pages":"Article 102688"},"PeriodicalIF":12.2,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-05DOI: 10.1016/j.cpr.2025.102686
Benjamin A. Katz , Mertcan Mutlu , Atulya Arya Kharbanda , Palomi Kurade , Geva Shenkman
Sexual and gender minority (SGM) individuals often suffer from a myriad of stressors within their social environments due to stigma and its outcomes (Meyer, 2003). Conversely, social support may impact SGM individuals' psychological resilience. To quantify the impact of their interpersonal environments, the current preregistered meta-analysis included 253 studies (N = 111,188) that reported associations between social support (i.e., family, peer, partner, school, work) and internalizing psychopathology (i.e., depression, anxiety, nonsuicidal self-injury, suicidality) among SGM samples. Overall, a small, negative association was observed, r = −0.26, with low levels of variance between studies. Larger effects were observed for depression than other measures of psychopathology, r = −0.29, while smaller effects were observed for suicidality, r = −0.17. Smaller effects were observed for samples with a larger share of bisexual individuals, and when a SGM-specific measure was used. Larger effects were observed for European studies performed in areas of greater structural stigma (but not for American studies). The negative association between social support and psychopathology was consistent across an array of demographic factors (e.g., age, gender, % white) and SGM identities (e.g., % gender minority). No evidence of publication bias was observed. These findings suggests that all forms of SGM social support are similarly associated with lower internalizing psychopathology to a small degree, most of all with regards to depression.
{"title":"Social support and internalizing psychopathology among sexual and gender minority individuals: A meta-analysis","authors":"Benjamin A. Katz , Mertcan Mutlu , Atulya Arya Kharbanda , Palomi Kurade , Geva Shenkman","doi":"10.1016/j.cpr.2025.102686","DOIUrl":"10.1016/j.cpr.2025.102686","url":null,"abstract":"<div><div>Sexual and gender minority (SGM) individuals often suffer from a myriad of stressors within their social environments due to stigma and its outcomes (<span><span>Meyer, 2003</span></span>). Conversely, social support may impact SGM individuals' psychological resilience. To quantify the impact of their interpersonal environments, the current preregistered meta-analysis included 253 studies (<em>N</em> = 111,188) that reported associations between social support (i.e., family, peer, partner, school, work) and internalizing psychopathology (i.e., depression, anxiety, nonsuicidal self-injury, suicidality) among SGM samples. Overall, a small, negative association was observed, <em>r</em> = −0.26, with low levels of variance between studies. Larger effects were observed for depression than other measures of psychopathology, <em>r</em> = −0.29, while smaller effects were observed for suicidality, <em>r</em> = −0.17. Smaller effects were observed for samples with a larger share of bisexual individuals, and when a SGM-specific measure was used. Larger effects were observed for European studies performed in areas of greater structural stigma (but not for American studies). The negative association between social support and psychopathology was consistent across an array of demographic factors (e.g., age, gender, % white) and SGM identities (e.g., % gender minority). No evidence of publication bias was observed. These findings suggests that all forms of SGM social support are similarly associated with lower internalizing psychopathology to a small degree, most of all with regards to depression.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"123 ","pages":"Article 102686"},"PeriodicalIF":12.2,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145689636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-03DOI: 10.1016/j.cpr.2025.102687
T.M. Lincoln, H. Romberg, D. Torrents-Rodas, A. Bott
Contemporary definitions of delusions highlight their resistance to conflicting evidence as the core feature, but there has been little progress in understanding why even explicit confrontation with contradicting evidence seldom leads to belief revision. This review aims to generate new hypotheses on delusion maintenance to inform research and clinical practice.
We systematically reviewed psychological models of belief maintenance and extracted their proposed mechanisms and moderators. The electronic search identified six dissociable perspectives: Associative learning, Bayesian inference, utility-informed, cognitive processing informed, dissonance-theory informed, and cross-disciplinary perspectives. The proposed mechanisms involved changing the sensory evidence to fit with one's prior belief (e.g. shifting attention to contextual cues, changing or reinterpreting sensory input), reducing the relevance of the prediction error (e.g., finding causes of the unexpected event, increasing the abstraction of the prior belief) and reinforcement (e.g. reduction of arousal). The moderators related to prior belief (e.g. its temporal stability, utility, or self-relevance), size of the prediction error, precision of the sensory evidence (e.g. quality, order), context (e.g. typicality, complexity), and individual differences (e.g. cognitive flexibility). We discuss how each proposed mechanism and moderator and their interactions align with current knowledge on delusions and offer compelling and novel explanations for delusion maintenance.
We conclude that delusion maintenance and systematization can be convincingly explained by combinations of prior belief precision, ambiguous input and situational characteristics and may not necessarily require neurobiological deficits or generalized biases. The hypotheses derived offer multiple new avenues for research and for optimizing the learning process in interventions for delusions.
{"title":"The ‘made-up mind’. Deriving new hypotheses on delusions from general psychological models of belief maintenance","authors":"T.M. Lincoln, H. Romberg, D. Torrents-Rodas, A. Bott","doi":"10.1016/j.cpr.2025.102687","DOIUrl":"10.1016/j.cpr.2025.102687","url":null,"abstract":"<div><div>Contemporary definitions of delusions highlight their resistance to conflicting evidence as the core feature, but there has been little progress in understanding why even explicit confrontation with contradicting evidence seldom leads to belief revision. This review aims to generate new hypotheses on delusion maintenance to inform research and clinical practice.</div><div>We systematically reviewed psychological models of belief maintenance and extracted their proposed mechanisms and moderators. The electronic search identified six dissociable perspectives: Associative learning, Bayesian inference, utility-informed, cognitive processing informed, dissonance-theory informed, and cross-disciplinary perspectives. The proposed mechanisms involved changing the sensory evidence to fit with one's prior belief (e.g. shifting attention to contextual cues, changing or reinterpreting sensory input), reducing the relevance of the prediction error (e.g., finding causes of the unexpected event, increasing the abstraction of the prior belief) and reinforcement (e.g. reduction of arousal). The moderators related to prior belief (e.g. its temporal stability, utility, or self-relevance), size of the prediction error, precision of the sensory evidence (e.g. quality, order), context (e.g. typicality, complexity), and individual differences (e.g. cognitive flexibility). We discuss how each proposed mechanism and moderator and their interactions align with current knowledge on delusions and offer compelling and novel explanations for delusion maintenance.</div><div>We conclude that delusion maintenance and systematization can be convincingly explained by combinations of prior belief precision, ambiguous input and situational characteristics and may not necessarily require neurobiological deficits or generalized biases. The hypotheses derived offer multiple new avenues for research and for optimizing the learning process in interventions for delusions.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"123 ","pages":"Article 102687"},"PeriodicalIF":12.2,"publicationDate":"2025-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145689594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-27DOI: 10.1016/j.cpr.2025.102684
Yangziying Lei , Jiale Xu , Yuanxiao Ma
Internet addiction has emerged as a global public health concern, with psychological distress recognized as a key contributing factor. Numerous studies have investigated the association between psychological distress and Internet addiction; however, their findings have remained inconsistent, and the moderating factors influencing this relationship have not been comprehensively examined. To address these gaps, the present study conducted a three-level meta-analysis to systematically assess the association between psychological distress and Internet addiction, as well as to explore potential moderators. In total, 135 studies involving 263,780 participants and 632 effect sizes were identified by a systematic literature search. The results revealed a significant positive correlation between psychological distress and Internet addiction. Furthermore, several variables significantly moderated this relationship, including study design, publication year, COVID-19 pandemic context, gender, age group, educational stage, country, living arrangement, measurement of Internet addiction, dimensions of Internet addiction, and types of Internet addiction. These findings provide more comprehensive insights to understand the complex link between psychological distress and Internet addiction and offer theoretical guidance for the development of targeted prevention and intervention strategies.
{"title":"The association between psychological distress and internet addiction: A systematic review and three-level meta-analysis","authors":"Yangziying Lei , Jiale Xu , Yuanxiao Ma","doi":"10.1016/j.cpr.2025.102684","DOIUrl":"10.1016/j.cpr.2025.102684","url":null,"abstract":"<div><div>Internet addiction has emerged as a global public health concern, with psychological distress recognized as a key contributing factor. Numerous studies have investigated the association between psychological distress and Internet addiction; however, their findings have remained inconsistent, and the moderating factors influencing this relationship have not been comprehensively examined. To address these gaps, the present study conducted a three-level meta-analysis to systematically assess the association between psychological distress and Internet addiction, as well as to explore potential moderators. In total, 135 studies involving 263,780 participants and 632 effect sizes were identified by a systematic literature search. The results revealed a significant positive correlation between psychological distress and Internet addiction. Furthermore, several variables significantly moderated this relationship, including study design, publication year, COVID-19 pandemic context, gender, age group, educational stage, country, living arrangement, measurement of Internet addiction, dimensions of Internet addiction, and types of Internet addiction. These findings provide more comprehensive insights to understand the complex link between psychological distress and Internet addiction and offer theoretical guidance for the development of targeted prevention and intervention strategies.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"123 ","pages":"Article 102684"},"PeriodicalIF":12.2,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145608744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}