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The cognitive theory of panic disorder: A systematic narrative review 恐慌症的认知理论:系统性叙事回顾
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-08-13 DOI: 10.1016/j.cpr.2024.102483
Saarim Yasin Aslam , Tiago Zortea , Paul Salkovskis

Background

The cognitive theory of panic disorder proposes that individuals with panic disorder have a relatively enduring tendency to catastrophically misinterpret bodily sensations resulting in panic attacks.

Aims

We investigated whether the evidence is consistent with the theory and its predictions, if updates are required and sought to identify future research considerations.

Methods

We searched Scopus, Web of Science, PsycInfo, EMBASE, MEDLINE and CINAHL (1986 to July 2024). Inclusion criteria were studies collecting quantitative data derived from panic disorder patients, testing one of the predictions and using appropriate outcome measures. Exclusion criteria were non-English language publications, all participants under the age of 18 and studies that were not published in a peer-reviewed journal. Quality was assessed using ‘QualSyst’ and synthesis was based on each prediction tested. PROPSERO registration #CRD42022332211.

Results

53 studies were identified amongst 49 publications. There was substantial evidence for all predictions. Three studies did not support the prediction tested and none were inconsistent.

Limitations

Most studies were ‘medium’ in quality and were predominately from female samples.

Conclusions

Findings are consistent with the theory and its predictions. Higher quality research is needed and implications for future research are discussed.

背景惊恐障碍的认知理论认为,惊恐障碍患者有一种相对持久的倾向,会对身体感觉产生灾难性的误解,从而导致惊恐发作。研究目的我们调查了相关证据是否与该理论及其预测一致,是否需要更新,并试图确定未来研究的注意事项。纳入标准是收集恐慌症患者的定量数据、测试其中一项预测并使用适当的结果测量指标的研究。排除标准为非英语出版物、所有参与者均未满 18 周岁以及未在同行评审期刊上发表的研究。使用 "QualSyst "对研究质量进行评估,并根据每项预测结果进行综合。PROPSERO注册号为CRD42022332211.结果在49篇出版物中确定了53项研究。所有预测均有大量证据支持。限制大多数研究的质量为 "中等",且主要来自女性样本。需要进行更高质量的研究,并讨论了对未来研究的影响。
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引用次数: 0
Scoping review of withdrawal's role in contemporary gaming disorder research: Conceptualizations and operationalizations 对戒断在当代游戏障碍研究中的作用进行范围界定:概念化和操作化
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-08-13 DOI: 10.1016/j.cpr.2024.102478
Sylwia Starzec , Jolanta Starosta , Aleksandra Zajas , Patrycja Kiszka , Sławomir Śpiewak , Paweł Strojny

The global gaming community now exceeds 3 billion players, prompting increased attention from social and medical sciences regarding gaming-related disorders. Internet Gaming Disorder (IGD) was incorporated into DSM-5 in 2013, and Gaming Disorder (GD) found its place in ICD-11 in 2019. A contentious criterion in IGD, not present in GD, revolves around withdrawal symptoms. This paper offers a theoretical foundation on gaming withdrawal symptoms in gaming-related disorders and conducts a scoping review of withdrawal operationalization and conceptualization in 40 selected studies, following PRISMA-ScR guidelines.

Most studies employed a correlation framework, relying on convenience samples and self-assessment questionnaires. A smaller portion focused on clinical samples and case studies. Withdrawal was predominantly conceptualized in terms of affective components, with less emphasis on behavioural, cognitive, physical, or neurological aspects. The prevailing terminology for gaming-related disorders was IGD, with only three studies referencing GD as defined in ICD-11. Notably, just six experimental studies included abstinence control.

We advocate for an expansion of research on withdrawal symptoms, particularly through experimental studies that implement abstinence within experimental groups and offer alternative operationalizations beyond dominant self-assessment measures.

目前,全球游戏玩家已超过 30 亿,这促使社会科学和医学界越来越关注与游戏相关的疾病。2013 年,网络游戏障碍(IGD)被纳入 DSM-5;2019 年,游戏障碍(GD)被纳入 ICD-11。IGD 中一个有争议的标准是戒断症状,而 GD 中则不存在这一标准。本文提供了游戏相关障碍中游戏戒断症状的理论基础,并根据 PRISMA-ScR 指南,对 40 项选定研究中的戒断操作化和概念化进行了范围审查。小部分研究侧重于临床样本和病例研究。戒断的概念主要体现在情感方面,而较少强调行为、认知、身体或神经方面。与游戏相关的疾病的主流术语是 IGD,只有三项研究引用了 ICD-11 中定义的 GD。我们主张扩大对戒断症状的研究,特别是通过在实验组中实施戒断的实验研究,并提供主流自我评估措施之外的其他操作方法。
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引用次数: 0
Gender, age, and longitudinal measurement invariance of child and adolescent depression scales: A systematic review 儿童和青少年抑郁量表的性别、年龄和纵向测量不变性:系统回顾
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-08-13 DOI: 10.1016/j.cpr.2024.102481
Pascal Schlechter , Mona Hillmann , Sharon A.S. Neufeld

Understanding developmental trajectories and gender differences in depressive symptoms is clinically relevant. Discerning true differences across gender, age groups, and time is based on the often-neglected premise of measurement invariance (MI) of child and adolescent depression scales. In this systematic review, we assessed available evidence for MI across gender, age groups, and time for depression scales validated in children and adolescents, in studies with at least one assessment under age 18. A literature search using Medline, PsychInfo, Scopus, Web of Science, and Google Scholar databases identified 42 studies that examined MI. MI of eleven scales was tested in 1–9 studies per scale. Conclusions are hampered by different factor solutions tested within some scales. All included questionnaires showed preliminary evidence for MI across gender. Across some studies, crying had higher factor loadings in females compared to males, indicating that crying may be differently related to depression across gender. MI evidence was preliminary in just four scales across time, mostly confined to ages 13–17. One study showed developmental conclusions differed when non-invariance is not accounted for in observed scores. Overall, evidence for MI in child and adolescent depression scales is currently limited.

了解抑郁症状的发展轨迹和性别差异具有临床意义。辨别不同性别、年龄组和时间之间的真正差异,需要以儿童和青少年抑郁量表的测量不变性(MI)这一经常被忽视的前提为基础。在本系统性综述中,我们评估了针对儿童和青少年的抑郁量表在不同性别、年龄组和时间之间测量不变性的现有证据,这些研究至少有一次评估是在 18 岁以下进行的。通过使用 Medline、PsychInfo、Scopus、Web of Science 和 Google Scholar 数据库进行文献检索,我们发现有 42 项研究对 MI 进行了检测。每个量表有 1-9 项研究对 11 个量表的 MI 进行了测试。一些量表中测试了不同的因子解决方案,这妨碍了结论的得出。所有收录的调查问卷都显示出不同性别的多元智能的初步证据。在一些研究中,女性哭泣的因子负荷高于男性,这表明不同性别的哭泣与抑郁的关系可能不同。在不同的时间段,只有四个量表显示了多元智能的初步证据,且大多局限于 13-17 岁。一项研究表明,如果不考虑观察分数中的非方差因素,发展方面的结论会有所不同。总体而言,目前儿童和青少年抑郁量表中的多元智能证据有限。
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引用次数: 0
The deficit in cognitive reappraisal capacity in individuals with anxiety or depressive disorders: meta-analyses of behavioral and neuroimaging studies 焦虑症或抑郁症患者认知再评价能力的缺陷:行为学和神经影像学研究的荟萃分析。
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-08-13 DOI: 10.1016/j.cpr.2024.102480
Xiaobing Cui , Qingwen Ding , Shuting Yu , Siyuan Zhang , Xuebing Li

Background

The deficit in cognitive reappraisal capacity is a key factor in developing and maintaining emotional disorders such as anxiety disorders and depressive disorders. However, the results from both neuroimaging and behavioral studies are mixed. Therefore, we systematically conducted a series of meta-analyses based on behavioral and neuroimaging studies to clarify this issue.

Methods

In behavioral meta-analyses, we used three-level random-effects models to summarize the overall effect sizes based on Hedges' g. In neuroimaging meta-analyses, we used SDM-PSI to summarize the brain activation patterns.

Results

Behavioral meta-analyses found that individuals with anxiety disorders or depressive disorders could reduce negative reactivity through reappraisal; the reduction of negative emotions through reappraisal by individuals with anxiety disorders was similar to that by healthy individuals; the reduction by depressive disorders was lower than that of healthy individuals. Neuroimaging meta-analyses showed that individuals with anxiety disorders or depressive disorders activated regions of cognitive control during cognitive reappraisal; the activation in individuals with anxiety disorders was lower than in healthy individuals; while the activation in individuals with depressive disorders was similar to that in healthy individuals.

Conclusion

Individuals with anxiety and depressive disorders showed dissociation in behaviour and neuroimaging patterns of cognitive reappraisal capacity deficit.

背景:认知再评价能力的缺陷是焦虑症和抑郁症等情绪障碍发生和维持的关键因素。然而,神经影像学和行为学研究的结果不一。因此,我们系统地进行了一系列基于行为学和神经影像学研究的荟萃分析,以澄清这一问题:在行为学荟萃分析中,我们使用三级随机效应模型来总结基于 Hedges'g 的总体效应大小;在神经影像学荟萃分析中,我们使用 SDM-PSI 来总结大脑激活模式:行为学荟萃分析发现,焦虑症或抑郁症患者可以通过重新评价来减少负面反应性;焦虑症患者通过重新评价减少负面情绪的程度与健康人相似;抑郁症患者通过重新评价减少负面情绪的程度低于健康人。神经影像学荟萃分析表明,焦虑症或抑郁症患者在认知再评价过程中激活了认知控制区域;焦虑症患者的激活程度低于健康人;而抑郁症患者的激活程度与健康人相似:结论:焦虑症和抑郁症患者在认知再评价能力缺陷的行为和神经影像学模式上存在差异。
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引用次数: 0
A meta-review of screening and treatment of electronic “addictions” 电子 "成瘾 "筛查和治疗的元综述
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-08-08 DOI: 10.1016/j.cpr.2024.102468
Jasara N. Hogan, Richard E. Heyman, Amy M. Smith Slep

Concerns surrounding electronic addictions, an umbrella term including any clinically significant technology-based addictive problem, have increased as technology has advanced. Although researchers and clinicians have observed detrimental effects associated with excessive technology use, there is no agreed-on definition or set of criteria for these problems. The lack of a consistent understanding of electronic addictions has led to a lack of consistency in both assessment and treatment studies, precluding strong recommendations for effective screening and clinical intervention. This meta-review integrates findings from 22 systematic reviews and meta-analyses of electronic addictions to determine which measures and interventions may effectively measure and treat electronic addictions. We conducted a meta-review using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Findings suggest that although some measures may have good internal consistency and reliability among college students, there was a general lack of consistency in how measures were used across studies, making comparison difficult. Psychological and exercise-based interventions were shown to reduce symptoms of electronic addictions short-term, but no treatment was superior to others in overall symptom reduction. Most included reviews raise serious concerns about the lack of consensus on what constitutes an electronic addiction. Consequently, it was not possible to draw conclusions about the overall efficacy of any measurement tools or interventions. We provide suggestions for next steps to establish the phenomenology of electronic addictions before additional research on assessment and intervention is conducted.

电子成瘾是一个总括性术语,包括任何具有临床意义的以技术为基础的成瘾问题,随着技术的进步,人们对电子成瘾的关注也越来越多。尽管研究人员和临床医生已经观察到过度使用技术所带来的有害影响,但对这些问题并没有一致的定义或标准。由于对电子成瘾缺乏一致的认识,导致评估和治疗研究缺乏一致性,无法为有效筛查和临床干预提供有力的建议。本荟萃综述整合了 22 项关于电子成瘾的系统综述和荟萃分析的研究结果,以确定哪些措施和干预方法可以有效衡量和治疗电子成瘾。我们采用《系统综述和荟萃分析首选报告项目》指南进行了荟萃综述。研究结果表明,尽管某些测量方法在大学生中可能具有良好的内部一致性和可靠性,但不同研究中使用的测量方法普遍缺乏一致性,因此很难进行比较。研究表明,心理干预和运动干预能在短期内减轻电子成瘾的症状,但在总体症状减轻方面,没有一种治疗方法优于其他治疗方法。大多数收录的综述都对什么是电子成瘾缺乏共识表示严重关切。因此,我们无法对任何测量工具或干预措施的总体疗效得出结论。我们对下一步工作提出了建议,以便在开展更多有关评估和干预的研究之前,确定电子成瘾的现象学。
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引用次数: 0
Assessment of suicidal thoughts and behaviors in adults: A systematic review of measure psychometric properties and implications for clinical and research utility 成人自杀想法和行为评估:对测量心理测量学特性及其对临床和研究用途的影响的系统回顾
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-08-01 DOI: 10.1016/j.cpr.2024.102464
Olivia H. Pollak , Ana E. Sheehan , Rachel F.L. Walsh , Auburn R. Stephenson , Holly Zell , Jenna Mayes , Hannah R. Lawrence , Alexandra H. Bettis , Richard T. Liu

High-quality clinical care and research on suicidal thoughts and behaviors (STBs) depends on availability and implementation of reliable and valid measures of STBs. In contrast to studies examining STB risk factors, screening instruments, or treatment, little research has rigorously examined the content, characteristics, and psychometric properties of STB measures themselves. This systematic review (1) identified STB measures that conform to empirically supported definitions of STBs, and (2) identified peer-reviewed papers reporting on the psychometric properties of these measures in adults. Data on psychometric properties and other measure characteristics were extracted. A total of 21 eligible measures were identified in the first stage. In the second stage, 70 articles (with 79 independent samples) were included with psychometric data in adult samples for 19 measures. Although there was support for strong internal consistency and content validity across many measures, face validity and clinical utility concerns were prevalent. Few measures comprehensively assessed suicidal behaviors, and interview-based assessments tended to show the strongest psychometric properties and clinical utility. Findings are discussed in the context of recommendations for improving existing measures, including future research to increase utility and translatability across clinical settings, delivery methods, and diverse populations.

有关自杀想法和行为(STBs)的高质量临床护理和研究取决于是否有可靠有效的 STBs 测量方法并能实施这些测量方法。与针对 STB 危险因素、筛查工具或治疗方法的研究相比,很少有研究对 STB 测量方法本身的内容、特点和心理测量特性进行严格的检查。本系统性综述(1)确定了符合经验支持的 STB 定义的 STB 测量方法,(2)确定了报道这些测量方法在成人中心理测量特性的同行评审论文。提取了有关心理测量特性和其他测量特征的数据。第一阶段共确定了 21 项符合条件的测量方法。在第二阶段,有 70 篇文章(包含 79 个独立样本)收录了 19 个测量指标在成人样本中的心理测量数据。尽管许多测量指标都具有较强的内部一致性和内容效度,但表面效度和临床效用方面的问题却普遍存在。很少有测量能全面评估自杀行为,而基于访谈的评估往往显示出最强的心理测量特性和临床实用性。本文结合改进现有测量方法的建议对研究结果进行了讨论,包括未来的研究,以提高在临床环境、实施方法和不同人群中的实用性和可转化性。
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引用次数: 0
The role of motivation in clinical presentation, treatment engagement and response in schizophrenia-spectrum disorders: A systematic review 动机在精神分裂症谱系障碍的临床表现、治疗参与度和反应中的作用:系统综述。
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-31 DOI: 10.1016/j.cpr.2024.102471
Helen Thai , Élodie C. Audet , Richard Koestner , Martin Lepage , Gillian A. O'Driscoll

Schizophrenia, a debilitating psychiatric disorder, has a long-term impact on social and occupational functioning. While negative symptoms, notably amotivation, are recognized as poor prognostic factors, the positive force of patient motivation (autonomous motivation) remains underexplored. This systematic review, guided by Self-Determination Theory (SDT), investigated the impact of motivation on clinical presentation, and treatment engagement and response in schizophrenia-spectrum disorders. Fifty-five independent studies (N = 6897), using 23 different motivation scales, met inclusion criteria. Results were categorized into cross-sectional and longitudinal correlates of autonomous motivation, and the effects of motivational interventions. Cross-sectionally, autonomous motivation was positively associated with social/occupational functioning, and negatively associated with negative and positive symptom severity. In longitudinal studies, baseline autonomous motivation predicted engagement in and response to social/occupational treatments, with mixed results in cognitive interventions. In the 16 randomized controlled trials (RCTs), the most common motivational interventions were individualized goal setting and goal attainment support, followed by increasing sense of competence by challenging defeatist beliefs, and enhancing relatedness by increasing contact time. Motivational interventions consistently increased autonomous motivation, treatment engagement and response. More studies are needed, particularly studies that monitor motivation during treatment: proximal assessments could facilitate the identification of treatment elements that impact motivation and engagement and inform treatment modifications to enhance the patient experience and improve treatment efficacy.

精神分裂症是一种使人衰弱的精神疾病,对社会和职业功能有长期影响。虽然消极症状,尤其是缺乏动力,被认为是不良预后因素,但患者动力(自主动力)的积极作用仍未得到充分探讨。本系统性综述以自我决定理论(SDT)为指导,研究了动机对精神分裂症谱系障碍的临床表现、治疗参与度和反应的影响。55 项独立研究(N = 6897)使用了 23 种不同的动机量表,符合纳入标准。研究结果分为自主动机的横向和纵向相关性以及动机干预的效果。从横截面来看,自主动机与社会/职业功能呈正相关,与消极和积极症状的严重程度呈负相关。在纵向研究中,基线自主动机预示着对社会/职业治疗的参与和反应,而认知干预的结果则好坏参半。在 16 项随机对照试验(RCTs)中,最常见的动机干预措施是个性化目标设定和目标实现支持,其次是通过挑战失败主义信念来增强能力感,以及通过增加接触时间来增强相关性。动机干预始终能提高自主动机、治疗参与度和反应。我们需要进行更多的研究,尤其是在治疗过程中监测治疗动机的研究:近端评估有助于确定影响治疗动机和参与度的治疗要素,并为治疗调整提供信息,以改善患者体验和提高治疗效果。
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引用次数: 0
Measures of mental imagery in emotional disorders: A COSMIN systematic review of psychometric properties 情绪障碍中的心理想象测量:COSMIN 心理测量学特性系统回顾
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-30 DOI: 10.1016/j.cpr.2024.102470
Stephen A. McIntyre , Jessica Richardson , Susan Carroll , Saava O'Kirwan , Chloe Williams , Victoria Pile

Background

Dysfunctional imagery processes characterise a range of emotional disorders. Valid, reliable, and responsive mental imagery measures may support the clinical assessment of imagery and advance research to develop theory and imagery-based interventions. We sought to review the psychometric properties of mental imagery measures relevant to emotional disorders.

Methods

A systematic review registered on the Open Science Framework was conducted using COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guidance. Five databases were searched. COSMIN tools were used to assess the quality of study methodologies and psychometric properties of measures.

Results

Twenty-three articles describing twenty-one self-report measures were included. Measures assessed various imagery processes and were organised into four groups based on related emotional disorders. Study methodological quality varied: measure development and reliability studies were generally poor, while internal consistency and hypothesis testing studies were higher quality. Most measurement properties assessed were of indeterminate quality.

Conclusion

Imagery measures were heterogenous and primarily disorder specific. Due to a lack of high-quality psychometric assessment, it is unclear whether most included imagery measures are valid, reliable, or responsive. Measures had limited evidence of content validity suggesting further research could engage clinical populations to ensure their relevance and comprehensiveness.

背景功能失调的意象过程是一系列情绪障碍的特征。有效、可靠且反应灵敏的心理意象测量方法可支持对意象的临床评估,并推动研究以发展理论和基于意象的干预措施。我们试图对与情绪障碍相关的心理意象测量方法的心理计量特性进行回顾。方法采用基于共识的健康测量工具选择标准(COSMIN)指南,在开放科学框架下进行了系统回顾。共检索了五个数据库。COSMIN 工具用于评估研究方法的质量和测量方法的心理测量特性。结果共纳入 23 篇文章,描述了 21 种自我报告测量方法。这些测量方法评估了各种意象过程,并根据相关的情绪障碍分为四组。研究方法的质量参差不齐:测量开发和可靠性研究普遍较差,而内部一致性和假设检验研究的质量较高。大多数评估的测量属性质量不确定。由于缺乏高质量的心理测量学评估,目前尚不清楚大多数被纳入的意象测量是否有效、可靠或反应灵敏。测量内容有效性的证据有限,这表明进一步的研究可以让临床人群参与进来,以确保其相关性和全面性。
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引用次数: 0
A systematic review and meta-ethnography of client and therapist perspectives of the therapeutic alliance in the context of psychotherapy and suicidal experiences 在心理治疗和自杀经历的背景下,对客户和治疗师对治疗联盟的看法进行系统回顾和元民族志研究。
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-29 DOI: 10.1016/j.cpr.2024.102469
Charlotte Huggett , Sarah Peters , Patricia Gooding , Natalie Berry , Daniel Pratt

This review aimed to develop a conceptual model of the therapeutic alliance in the context of psychotherapy and suicidal experiences from therapist and client perspectives. The protocol was pre-registered on PROSPERO (CRD42021268273). MEDLINE, PsycINFO, Web of Science, Embase and CINAHL were systematically searched from database inception to April 2024. Eligible studies were peer-reviewed, qualitative, and included client and/or therapist's perspectives of the therapeutic alliance in the context of psychotherapy and suicidal experiences. Studies were critically appraised and analysed using a meta-ethnography approach involving a reciprocal translation of studies and line of argument synthesis. Thirty-seven papers were included, generating two overarching themes; ‘Working on the edge’ and ‘Being ready, willing, and able to build an alliance in the context of suicidal experiences’. Therapeutic alliance in the context of suicidal experiences is unique, fluid, potentially lifesaving, and influenced by multiple inter-connected internal and external processes and systems. Clinical implications emphasise the need to improve training, supervision, and support for therapists to equip them with the additional skills required in navigating the intricacies of the therapeutic alliance with clients who have suicidal experiences. Flexibly interweaving risk assessment into therapeutic conversation was beneficial to the alliance with suicidal clients and enhanced their safety.

本综述旨在从治疗师和客户的角度,为心理治疗和自杀经历中的治疗联盟建立一个概念模型。该研究方案已在 PROSPERO(CRD42021268273)上预先注册。从数据库建立之初到 2024 年 4 月,对 MEDLINE、PsycINFO、Web of Science、Embase 和 CINAHL 进行了系统检索。符合条件的研究均经过同行评审,为定性研究,内容包括客户和/或治疗师对心理治疗和自杀经历背景下的治疗联盟的看法。我们采用元人种学方法对研究进行了批判性评估和分析,包括研究的互译和论点的综合。37篇论文被收录其中,并产生了两个首要主题:"在边缘工作 "和 "准备好、愿意并能够在自杀经历的背景下建立联盟"。自杀经历背景下的治疗联盟是独特的、多变的、有可能挽救生命的,并受到多个相互关联的内外部过程和系统的影响。临床意义强调,需要加强对治疗师的培训、监督和支持,使他们掌握与有自杀经历的客户建立错综复杂的治疗联盟所需的额外技能。将风险评估灵活地融入治疗谈话中,有利于与有自杀倾向的求助者建立联盟关系,并增强他们的安全感。
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引用次数: 0
Evaluating the validity of eye-tracking tasks and stimuli in detecting high-risk infants later diagnosed with autism: A meta-analysis 评估眼动追踪任务和刺激物在检测后来被诊断为自闭症的高危婴儿方面的有效性:荟萃分析
IF 13.7 1区 心理学 Q1 PSYCHOLOGY, CLINICAL Pub Date : 2024-07-14 DOI: 10.1016/j.cpr.2024.102466
Wenwen Hou , Yingying Jiang , Yunmei Yang , Liqi Zhu , Jing Li

Gaze abnormalities are well documented in infants at elevated risk for autism spectrum disorder (ASD). However, variations in experimental design and stimuli across studies have led to mixed results. The current meta-analysis aimed to identify which type of eye tracking task and stimulus are most effective at differentiating high-risk infants (siblings of children with ASD) who later meet diagnosis criteria from low-risk infants without familial autism. We synthesized 35 studies that used eye tracking to investigate gaze behavior in infants at high genetic risk for autism before 2 years of age. We found that stimulus features, regions of interest (ROIs) and study quality moderated effect sizes across studies. Overall, dynamic stimuli and socially-relevant regions in the social stimuli (i.e. the target and activity of characters' shared focus) reliably detected high-risk infants who later develop ASD. Attention disengagement task and stimuli depicting interactions between human and nonhuman characters could identify high-risk infants who later develop ASD and those who have autism-related symptoms but do not meet the diagnostic criteria as well. These findings provide sensitive and reliable early markers of ASD, which is helpful to develop objective and quantitative early autism screening and intervention tools.

在自闭症谱系障碍(ASD)高风险婴儿中,凝视异常是有据可查的。然而,不同研究在实验设计和刺激方面的差异导致了结果的不一致。目前的荟萃分析旨在确定哪种类型的眼动跟踪任务和刺激能最有效地将日后符合诊断标准的高风险婴儿(患有 ASD 儿童的兄弟姐妹)与无家族性自闭症的低风险婴儿区分开来。我们综合了 35 项研究,这些研究利用眼动追踪技术调查了 2 岁前自闭症高遗传风险婴儿的注视行为。我们发现,刺激特征、感兴趣区(ROIs)和研究质量调节了不同研究的效应大小。总体而言,动态刺激和社会刺激中的社会相关区域(即人物共同关注的目标和活动)能可靠地检测出后来患上自闭症的高风险婴儿。注意力分离任务和描绘人类与非人类角色之间互动的刺激物可以识别出日后发展为自闭症的高危婴儿,以及那些有自闭症相关症状但不符合诊断标准的婴儿。这些发现提供了敏感可靠的自闭症早期标记,有助于开发客观定量的早期自闭症筛查和干预工具。
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引用次数: 0
期刊
Clinical Psychology Review
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