There is good reason to implicate self-regulation in our digital recreation duration, choices, and behaviours. However, the direction, degree, and diversity of their association is unclear. To offer more robust and nuanced evidence to this issue of acute public concern, the current study presents a comprehensive meta-analysis of the associations between self-regulation and digital recreation from birth to adolescence – consolidating 183 studies reporting 232 associations from 234,476 children and adolescents. Across these studies, digital recreation clustered into investigations of screen time, features of problematic digital engagement, exposure to violent content, communicating with strangers online, sexting, and media multitasking. Although a pattern of negative bivariate associations was observed between self-regulation and aspects of digital recreation, the strength of association for screen time was weak (r = −.04 for computer use to r = −.15 for social media use). Once control variables were considered, relationships with exposure to violent digital content were rendered similarly trivial, suggesting other variables likely account for these correlations. This reduces our confidence in these associations. In contrast, lower self-regulation was more highly associated with problematic engagement (r = −.28 for problematic gaming to r = −.41 for problematic mobile phone use), communicating with strangers online (r = −.18), and sexting (r = −.20). This pattern of results points to a relationship that is variable by type of digital activity, which in our meta-analyses ranged from null to strong and negative. Where a relationship exists, it may be bi-directional given associations remained for longitudinal studies that positioned either self-regulation or digital recreation as predictor. Most moderators of these associations were non-significant, although the negative association of self-regulation with time spent gaming was increasingly strong with increasing participant age. This study instigates a disentangling of the nature of the relationship between self-regulation and digital choices and behaviours across the early stages of life.