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Distal femoral fractures: periprosthetic fractures have four times more complications than non-periprosthetic fractures and cerclage should be avoided: retrospective analysis of 206 patients. 股骨远端骨折:假体周围骨折的并发症是非假体周围骨折的四倍,应避免使用环扎术:对206例患者的回顾性分析。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-03 DOI: 10.1186/s10195-024-00782-2
Martin Direder, Cornelia Naß, Julian Ramin Andresen, Theresa Dannenmann, Florian Bur, Stefan Hajdu, Thomas Haider

Background: Distal femoral fractures account for less than 1% of all fractures. The therapy of choice is usually surgical stabilization. Despite advances in implant development over the past few years, complication rate remains comparatively high. The aim of this study is to analyze our results with plate fixation of distal femoral fractures with a focus on complication and fracture healing rates.

Methods: In this retrospective cohort study, patients (> 18 years) with distal femoral fractures treated at an urban level I trauma center between 2015 and 2022 were analyzed.

Results: In total, 206 patients (167 female, 39 male) with an average age of 75 (SD 16) years were diagnosed with a fracture of the distal femur. One hundred fourteen of these patients were treated surgically by means of plate osteosynthesis. In 13 cases (11.41%), a revision procedure had to be performed. The indication for surgical revision was mechanical failure in eight cases (7.02%) and septic complication in five cases (4.39%). Periprosthetic fractures were more likely to cause complications overall (19.6% versus 4.76%) and further included all documented septic complications. The analysis of modifiable surgical factors in the context of plate osteosynthesis showed higher complication rates for cerclage in the fracture area compared with plate-only stabilizations (44.44% versus 22.22%).

Conclusions: The data show an increased amount of revisions and a significantly higher number of septic complications in the treatment of periprosthetic fractures of the distal femur compared with non-periprosthetic fractures. The detected combination of plates together with cerclage was associated with higher complication rates. Level of evidence Level III retrospective comparative study.

背景介绍股骨远端骨折在所有骨折中所占比例不到 1%。首选疗法通常是手术稳定。尽管过去几年植入物的发展取得了进步,但并发症发生率仍然相对较高。本研究旨在分析我们对股骨远端骨折进行钢板固定的结果,重点关注并发症和骨折愈合率:在这项回顾性队列研究中,分析了 2015 年至 2022 年期间在城市一级创伤中心接受治疗的股骨远端骨折患者(18 岁以上):共有 206 名患者(167 名女性,39 名男性)被诊断为股骨远端骨折,平均年龄为 75 岁(SD 16)。其中 114 名患者接受了钢板骨合成手术治疗。13例(11.41%)患者必须进行翻修手术。其中8例(7.02%)的手术翻修指征是机械损伤,5例(4.39%)的手术翻修指征是化脓性并发症。假体周围骨折更容易引起并发症(19.6%对4.76%),而且还包括所有记录在案的化脓性并发症。对钢板骨合成术中可改变的手术因素进行的分析表明,与单纯钢板稳定术相比,在骨折区域进行陶瓷包扎的并发症发生率更高(44.44% 对 22.22%):数据显示,在治疗股骨远端假体周围骨折时,与非假体周围骨折相比,翻修次数增加,化脓性并发症明显增多。经检测,将钢板与卡环结合使用的并发症发生率更高。证据等级 III 级回顾性比较研究。
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引用次数: 0
Revision shoulder arthroplasty and proximal humeral bone loss: a comprehensive review and proposal of a new algorithm of management. 翻修肩关节置换术与肱骨近端骨质流失:全面回顾并提出新的管理算法。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-09-03 DOI: 10.1186/s10195-024-00784-0
Angelo Baldari, Luca Saccone, Antonio Caldaria, Edoardo Giovannetti de Sanctis, Gian Mauro De Angelis D'Ossat, Luca La Verde, Alessio Palumbo, Francesco Franceschi

With the rising prevalence of shoulder arthroplasty, the incidence of revision shoulder arthroplasty is also increasing. The complexity of these revision procedures poses significant challenges, with bone loss being a critical factor impacting treatment outcomes. Addressing substantial humeral bone defects is crucial for ensuring implant stability and functionality. A comprehensive literature review was conducted using PubMed, Medline, and Google Scholar to identify existing classification systems for proximal humeral bone loss in the context of revision shoulder arthroplasty. The study assessed the advantages and limitations of these classifications, using this information to propose a new diagnostic and therapeutic algorithm. Several classification systems for proximal humeral bone loss were identified. McLendon et al. classify proximal humeral bone loss based on a 5-cm bone loss threshold and suggest an allograft prosthesis composite for losses exceeding this limit. Boileau's system stratifies bone loss into four types based on the extent of loss, with specific recommendations for each category. The PHAROS classification provides a detailed anatomical assessment but lacks quantitative precision. The proposed PHBL-SCORe system offers a novel algorithm incorporating preoperative radiographic measurements to determine the percentage of bone loss and guide treatment options. Proximal humeral bone loss presents significant challenges in revision shoulder arthroplasty, necessitating precise preoperative planning and classification to guide surgical intervention. Existing classification systems provide valuable frameworks but often rely on average population values, neglecting individual anatomical variations. The proposed PHBL-SCORe system offers a patient-specific approach, improving the accuracy of bone loss assessment and optimizing treatment strategies. Implementing this classification in clinical practice could enhance surgical outcomes and reduce complications associated with rRSA (revision Reverse Shoulder arthroplasty). Further studies are required to validate this algorithm and explore its long-term efficacy in diverse patient populations.

随着肩关节置换术发病率的上升,肩关节置换翻修术的发病率也在增加。这些翻修手术的复杂性带来了巨大的挑战,骨质流失是影响治疗效果的关键因素。解决肱骨骨质严重缺损是确保植入物稳定性和功能性的关键。我们使用 PubMed、Medline 和 Google Scholar 进行了全面的文献综述,以确定翻修肩关节置换术中肱骨近端骨质流失的现有分类系统。研究评估了这些分类的优势和局限性,并利用这些信息提出了一种新的诊断和治疗算法。研究发现了几种肱骨近端骨质流失的分类系统。McLendon等人根据5厘米骨质流失阈值对肱骨近端骨质流失进行分类,并建议对超过这一阈值的骨质流失采用同种异体假体复合治疗。Boileau 的系统根据骨质流失的程度将骨质流失分为四种类型,并针对每种类型提出了具体建议。PHAROS 分类法提供了详细的解剖评估,但缺乏定量的精确性。所提出的 PHBL-SCORe 系统提供了一种新颖的算法,结合术前影像学测量来确定骨质流失的百分比并指导治疗方案。肱骨近端骨质流失给翻修肩关节置换术带来了巨大挑战,需要精确的术前规划和分类来指导手术干预。现有的分类系统提供了有价值的框架,但往往依赖于群体的平均值,忽略了个体的解剖差异。提议的 PHBL-SCORe 系统提供了一种针对患者的方法,提高了骨质流失评估的准确性并优化了治疗策略。在临床实践中采用这种分类方法可以提高手术效果,减少与翻修反向肩关节置换术(rRSA)相关的并发症。还需要进一步的研究来验证这种算法,并探索其在不同患者群体中的长期疗效。
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引用次数: 0
Gender-specific factors influencing the glenoid version and reference values for it. 影响盂成形的性别特异性因素及其参考值。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-16 DOI: 10.1186/s10195-024-00778-y
Cornelius Sebastian Fischer, Matthias Floß, Till Ittermann, Christoph Emanuel Gonser, Ryan Giordmaina, Robin Bülow, Carsten-Oliver Schmidt, Jörn Lange

Background: Glenoid version is an important factor in the evaluation of shoulder stability and shoulder pathologies. However, there are neither established reference values nor known factors that influence the glenoid version, even though valid reference values are needed for diagnostic and orthopaedic surgery like corrective osteotomy and total or reverse shoulder arthroplasty (TSA/RSA). The aim of our population-based study was to identify factors influencing the glenoid version and to establish reference values from a large-scale population cohort.

Results: Our study explored the glenoid versions in a large sample representing the general adult population. We investigated 3004 participants in the population-based Study of Health in Pomerania (SHIP). Glenoid version was measured for both shoulders via magnetic resonance imaging (MRI). Associations with the glenoid version were calculated for sex, age, body height, body weight and BMI. The reference values for glenoid version in the central European population range between -9° and 7.5°, while multiple factors are associated with the glenoid version.

Conclusion: To achieve a reliable interpretation prior to orthopaedic surgery, sex- and age-adjusted reference values are proposed.

背景:盂成形是评估肩关节稳定性和肩关节病变的一个重要因素。然而,尽管诊断和矫形手术(如矫正截骨术和全肩或反向肩关节置换术(TSA/RSA))需要有效的参考值,但目前既没有确定的参考值,也不知道影响盂成形的因素。我们这项基于人群的研究旨在确定影响盂成形的因素,并从大规模人群队列中建立参考值:我们的研究探讨了代表普通成年人群的大样本中的盂兰盆版本。我们调查了以人口为基础的波美拉尼亚健康研究(SHIP)中的 3004 名参与者。通过磁共振成像(MRI)测量了双肩的盂成形度。计算了性别、年龄、身高、体重和体重指数与盂兰盆骨折的关系。中欧人群的盂成形度参考值介于-9°和7.5°之间,而多种因素与盂成形度有关:结论:为了在骨科手术前获得可靠的解释,建议采用按性别和年龄调整的参考值。
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引用次数: 0
Polyethylene liner dissociation in total hip arthroplasty: a retrospective case-control study on a single implant design. 全髋关节置换术中的聚乙烯衬垫解离:对单一植入物设计的回顾性病例对照研究。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-14 DOI: 10.1186/s10195-024-00785-z
S Pagano, J F Plate, T Kappenschneider, J Reinhard, M Scharf, G Maderbacher

Background: Modular acetabular components for total hip arthroplasty (THA) provide intraoperative flexibility; however, polyethylene liner dissociation may occur. This study aimed to examine the incidence and causes of liner dissociation associated with a specific acetabular component design at a single centre.

Materials and methods: A retrospective analysis of 7027 patients who underwent primary THA was performed to identify isolated liner dislocations. Patient demographics, clinical presentations, surgical and implant details, and both radiographic and computed tomography (CT) findings were analysed. Patients with liner dislocation were matched to a control group via 2:1 propensity score matching, and a logistic regression analysis was employed to identify associated risk factors.

Results: A total of 32 patients (0.45%) experienced liner dislocation at a mean 71.47 ± 60.10 months post surgery. Significant factors contributing to dislocations included the use of a conventional compared with a highly crosslinked polyethylene component (p = 0.049) and screw fixation (p = 0.028). Radiographic and CT analysis highlighted the importance of proper component orientation, revealing that patients experiencing dislocations demonstrated significantly lower acetabular cup anteversion angles (p = 0.001) compared with the control group. Impingement and malposition, identified in 41% and 47% of the cases, respectively, further underscored the multifactorial nature of dislocation risks.

Conclusions: While the overall rate of polyethylene liner dislocation was low, the findings of this study highlight the importance of appropriate cup placement to decrease the risk of dissociation. It further substantiates the influence of impingement and malposition in liner displacement, with increased mechanical stress exerted on the locking mechanism under adverse conditions and the potential risk increase due to screw placement.

背景:用于全髋关节置换术(THA)的模块化髋臼组件具有术中灵活性,但可能会发生聚乙烯衬垫分离。本研究的目的是在一个中心检查与特定髋臼组件设计相关的衬垫解离的发生率和原因:对7027名接受初级THA的患者进行回顾性分析,以确定孤立的衬垫脱位。分析了患者的人口统计学特征、临床表现、手术和植入物细节,以及X光和计算机断层扫描(CT)结果。通过2:1倾向得分匹配法将衬垫脱位患者与对照组进行匹配,并采用逻辑回归分析确定相关风险因素:共有32名患者(0.45%)在术后平均71.47 ± 60.10个月出现衬垫脱位。导致脱位的重要因素包括使用传统聚乙烯组件(p = 0.049)和螺钉固定(p = 0.028),而使用高交联聚乙烯组件(p = 0.049)和螺钉固定(p = 0.028)。X光片和CT分析强调了组件正确定位的重要性,显示与对照组相比,脱位患者的髋臼杯反转角度明显较低(p = 0.001)。在41%和47%的病例中分别发现了撞击和错位,这进一步强调了脱位风险的多因素性质:虽然聚乙烯衬垫脱位的总体发生率较低,但本研究结果强调了适当的髋臼杯置入对降低脱位风险的重要性。它进一步证实了撞击和位置不正对衬垫脱位的影响,在不利条件下锁定机制受到的机械应力会增加,螺钉置入可能会增加风险。
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引用次数: 0
Cement loaded with high-dose gentamicin and clindamycin does not reduce the risk of subsequent infection after aseptic total hip or knee revision arthroplasty: a preliminary study. 无菌全髋关节或膝关节翻修关节置换术后,装入大剂量庆大霉素和林可霉素的水泥并不能降低后续感染的风险:一项初步研究。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-07-24 DOI: 10.1186/s10195-024-00775-1
Ceyran Hamoudi, Marie Hamon, Aurélie Reiter-Schatz, Pierre-Antoine Debordes, Jeannot Gaudias, Cécile Rondé-Oustau, Jean-Yves Jenny

Purpose: The aim of this study was to quantify the prophylactic effect of high-dose gentamicin and clindamycin antibiotic-loaded bone cement (ALBC) during revision total hip (rTHA) or knee (rTKA) arthroplasty for aseptic reasons. The hypothesis was that the raw surgical site infection (SSI) rate is lower when this particular cement is used in comparison with cement loaded with standard-dose gentamicin during rTHA or rTKA for aseptic reasons.

Methods: This retrospective study included 290 consecutive patients undergoing aseptic rTHA or rTKA. Two consecutive cohorts were defined: the first (control group) involved 145 patients where ALBC with gentamicin only was used; the second (study group) involved 145 patients where ALBC with high-dose gentamicin and clindamycin was used. The primary endpoint was the raw SSI rate after 24 months.

Results: The raw SSI rate was 8/145 (6%) in the control group and 13/145 (9%) in the study group (odds ratio 0.62, p = 0.26). There was a significant impact of the presence of any risk factor on the SSI rate (15/100 versus 6/169, odds ratio = 4.25, p = 0.002), but no significant impact of any individual risk factor. No complication or side effect related to ALBC was observed in either group.

Conclusion: These results do not support the routine use of gentamicin and clindamycin ALBC for fixation of revision implants after rTHA and rTKA for aseptic reasons.

目的:本研究旨在量化高剂量庆大霉素和克林霉素抗生素骨水泥(ALBC)在无菌原因的翻修全髋(rTHA)或膝(rTKA)关节成形术中的预防效果。假设在无菌原因的翻修全髋关节置换术(rTHA)或膝关节置换术(rTKA)中使用这种特殊骨水泥与使用标准剂量庆大霉素的骨水泥相比,手术部位感染(SSI)的发生率更低:这项回顾性研究包括290名连续接受无菌rTHA或rTKA的患者。确定了两个连续队列:第一个队列(对照组)包括145名仅使用庆大霉素的ALBC患者;第二个队列(研究组)包括145名使用大剂量庆大霉素和克林霉素的ALBC患者。主要终点是 24 个月后的原始 SSI 感染率:对照组的原始 SSI 感染率为 8/145(6%),研究组为 13/145(9%)(几率比 0.62,P = 0.26)。任何风险因素的存在都会对 SSI 感染率产生重大影响(15/100 对 6/169,几率比 = 4.25,p = 0.002),但任何单个风险因素都不会产生重大影响。两组患者均未观察到与ALBC相关的并发症或副作用:这些结果不支持常规使用庆大霉素和克林霉素ALBC固定rTHA和rTKA术后因无菌原因而翻修的植入物。
{"title":"Cement loaded with high-dose gentamicin and clindamycin does not reduce the risk of subsequent infection after aseptic total hip or knee revision arthroplasty: a preliminary study.","authors":"Ceyran Hamoudi, Marie Hamon, Aurélie Reiter-Schatz, Pierre-Antoine Debordes, Jeannot Gaudias, Cécile Rondé-Oustau, Jean-Yves Jenny","doi":"10.1186/s10195-024-00775-1","DOIUrl":"10.1186/s10195-024-00775-1","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to quantify the prophylactic effect of high-dose gentamicin and clindamycin antibiotic-loaded bone cement (ALBC) during revision total hip (rTHA) or knee (rTKA) arthroplasty for aseptic reasons. The hypothesis was that the raw surgical site infection (SSI) rate is lower when this particular cement is used in comparison with cement loaded with standard-dose gentamicin during rTHA or rTKA for aseptic reasons.</p><p><strong>Methods: </strong>This retrospective study included 290 consecutive patients undergoing aseptic rTHA or rTKA. Two consecutive cohorts were defined: the first (control group) involved 145 patients where ALBC with gentamicin only was used; the second (study group) involved 145 patients where ALBC with high-dose gentamicin and clindamycin was used. The primary endpoint was the raw SSI rate after 24 months.</p><p><strong>Results: </strong>The raw SSI rate was 8/145 (6%) in the control group and 13/145 (9%) in the study group (odds ratio 0.62, p = 0.26). There was a significant impact of the presence of any risk factor on the SSI rate (15/100 versus 6/169, odds ratio = 4.25, p = 0.002), but no significant impact of any individual risk factor. No complication or side effect related to ALBC was observed in either group.</p><p><strong>Conclusion: </strong>These results do not support the routine use of gentamicin and clindamycin ALBC for fixation of revision implants after rTHA and rTKA for aseptic reasons.</p>","PeriodicalId":48603,"journal":{"name":"Journal of Orthopaedics and Traumatology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11269536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obesity-associated outcomes after ACL reconstruction: a propensity-score-matched analysis of the US Nationwide Inpatient Sample 2005-2018. 前交叉韧带重建术后与肥胖相关的结果:2005-2018 年美国全国住院患者样本倾向得分匹配分析。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-07-24 DOI: 10.1186/s10195-024-00779-x
Zhaoyi Fang, Wenxin Liu

Background: Anterior cruciate ligament (ACL) injuries are common among physically active individuals, and obesity may increase the risk of such injuries due to factors like biomechanical stress on the knee. We aimed to determine if obesity affects postoperative outcomes after ACL reconstruction.

Methods: Data from adults aged 20 years and older with ACL injuries who underwent inpatient reconstruction from 2005 to 2018 were extracted from the United States (US) Nationwide Inpatient Sample (NIS) database. Patients were divided into two groups based on the presence of co-existing obesity, defined as a body mass index (BMI) ≥ 30 kg/m2. Propensity-score matching (PSM) was employed to balance between-group differences. Associations between obesity and concomitant meniscus injury, length of stay (LOS), post-procedural complications, and non-routine discharge were examined using univariate and multivariable logistic and linear regressions.

Results: After PSM, data from 1323 patients (representing 6396 individuals in the US) were analyzed. Of these, 441 (33%) were classified as obese, while 882 (67%) were not obese. After adjustment, obesity was significantly associated with a longer LOS (adjusted beta (aBeta) = 0.32, 95% confidence interval (CI) 0.31-0.321) and an increased likelihood of non-routine discharge (adjusted OR (aOR) = 2.18, 95% CI 1.47-3.22). There were no significant associations between obesity and concomitant meniscus injury (aOR = 1.04, 95% CI 0.81-1.32) or post-procedural complications (aOR = 0.97, 95% CI 0.74-1.27).

Conclusions: In patients undergoing ACL reconstruction in the US, obesity is independently associated with a longer LOS and a higher risk of non-routine discharge. Nevertheless, obesity does not appear to be associated with concomitant meniscus injury or post-procedural complications.

背景:前交叉韧带(ACL)损伤在运动量大的人群中很常见,而肥胖可能会因膝关节的生物力学压力等因素而增加此类损伤的风险。我们旨在确定肥胖是否会影响前交叉韧带重建术后的效果:我们从美国全国住院病人抽样(NIS)数据库中提取了2005年至2018年接受住院重建的前交叉韧带损伤的20岁及以上成年人的数据。根据是否合并肥胖(定义为体重指数(BMI)≥ 30 kg/m2)将患者分为两组。采用倾向分数匹配法(PSM)来平衡组间差异。采用单变量和多变量逻辑回归及线性回归研究了肥胖与伴随的半月板损伤、住院时间(LOS)、术后并发症和非正常出院之间的关系:在 PSM 之后,对 1323 名患者(代表美国 6396 人)的数据进行了分析。其中 441 人(33%)被归类为肥胖,882 人(67%)不肥胖。经过调整后,肥胖与较长的 LOS(调整后的贝塔值 (aBeta) = 0.32,95% 置信区间 (CI) 0.31-0.321)和非正常出院的可能性增加(调整后的 OR (aOR) = 2.18,95% CI 1.47-3.22)有显著相关性。肥胖与伴随的半月板损伤(aOR = 1.04,95% CI 0.81-1.32)或术后并发症(aOR = 0.97,95% CI 0.74-1.27)之间无明显关联:结论:在美国接受前交叉韧带重建术的患者中,肥胖与较长的住院时间和较高的非正常出院风险密切相关。结论:在美国接受前交叉韧带重建术的患者中,肥胖与较长的住院时间和较高的非正常出院风险无关,但肥胖似乎与伴随的半月板损伤或术后并发症无关。
{"title":"Obesity-associated outcomes after ACL reconstruction: a propensity-score-matched analysis of the US Nationwide Inpatient Sample 2005-2018.","authors":"Zhaoyi Fang, Wenxin Liu","doi":"10.1186/s10195-024-00779-x","DOIUrl":"10.1186/s10195-024-00779-x","url":null,"abstract":"<p><strong>Background: </strong>Anterior cruciate ligament (ACL) injuries are common among physically active individuals, and obesity may increase the risk of such injuries due to factors like biomechanical stress on the knee. We aimed to determine if obesity affects postoperative outcomes after ACL reconstruction.</p><p><strong>Methods: </strong>Data from adults aged 20 years and older with ACL injuries who underwent inpatient reconstruction from 2005 to 2018 were extracted from the United States (US) Nationwide Inpatient Sample (NIS) database. Patients were divided into two groups based on the presence of co-existing obesity, defined as a body mass index (BMI) ≥ 30 kg/m<sup>2</sup>. Propensity-score matching (PSM) was employed to balance between-group differences. Associations between obesity and concomitant meniscus injury, length of stay (LOS), post-procedural complications, and non-routine discharge were examined using univariate and multivariable logistic and linear regressions.</p><p><strong>Results: </strong>After PSM, data from 1323 patients (representing 6396 individuals in the US) were analyzed. Of these, 441 (33%) were classified as obese, while 882 (67%) were not obese. After adjustment, obesity was significantly associated with a longer LOS (adjusted beta (aBeta) = 0.32, 95% confidence interval (CI) 0.31-0.321) and an increased likelihood of non-routine discharge (adjusted OR (aOR) = 2.18, 95% CI 1.47-3.22). There were no significant associations between obesity and concomitant meniscus injury (aOR = 1.04, 95% CI 0.81-1.32) or post-procedural complications (aOR = 0.97, 95% CI 0.74-1.27).</p><p><strong>Conclusions: </strong>In patients undergoing ACL reconstruction in the US, obesity is independently associated with a longer LOS and a higher risk of non-routine discharge. Nevertheless, obesity does not appear to be associated with concomitant meniscus injury or post-procedural complications.</p>","PeriodicalId":48603,"journal":{"name":"Journal of Orthopaedics and Traumatology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11269535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative outcomes of uncemented and cemented stem revision in managing periprosthetic femoral fractures: a retrospective cohort study. 治疗股骨假体周围骨折的非骨水泥和骨水泥柄翻修效果比较:一项回顾性队列研究。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-07-18 DOI: 10.1186/s10195-024-00777-z
Michael Axenhus, Sebastian Mukka, Martin Magnéli, Olof Sköldenberg

Introduction: Periprosthetic femoral fractures (PFFs) following hip arthroplasty, especially Vancouver B2 and B3 fractures, present a challenge due to the association with a loose femoral stem, necessitating either open reduction and internal fixation or stem revision. This study aims to compare outcomes between uncemented and cemented stem revisions in managing Vancouver B2 and B3 fractures, considering factors such as hip-related complications, reoperations, and clinical outcome.

Methods: A retrospective cohort study was conducted at Danderyd Hospital, Sweden, from 2008 to 2022, encompassing operatively treated Vancouver B2 and B3 fractures. Patients were categorized into uncemented and cemented stem revision groups, with data collected on complications, revision surgeries, fracture healing times, and clinical outcomes.

Results: A total of 241 patients were identified. Significant differences were observed between the two groups in patient demographics, with the cemented group comprising older patients and more females. Follow up ranged from 1 to 15 years. Average follow up time was 3.9 years for the cemented group and 5.5 years for the uncemented group. The cemented stems demonstrated lower rates of dislocation (8.9% versus 22.5%, P = 0.004) and stem loosening (0.6% versus 9.3%, P = 0.004) than the uncemented method. Moreover, the cemented group exhibited shorter fracture healing times (11.4 weeks versus 16.7 weeks, P = 0.034). There was no difference in clinical outcome between groups. Mortality was higher in the cemented group.

Conclusions: This retrospective study indicates that cemented stem revision for Vancouver B2-3 fractures is correlated with lower dislocation and stem loosening rates, necessitating fewer reoperations and shorter fracture healing times compared with the uncemented approach. The cemented group had a notably higher mortality rate, urging caution in its clinical interpretation.

Level of evidence iii:

简介:髋关节置换术后的股骨假体周围骨折(PFFs),尤其是温哥华B2和B3骨折,由于与松动的股骨干有关,需要进行切开复位和内固定术或骨干翻修,因此是一项挑战。本研究旨在考虑髋关节相关并发症、再手术和临床效果等因素,比较非骨水泥和骨水泥股骨干翻修术治疗温哥华B2和B3骨折的效果:瑞典Danderyd医院于2008年至2022年期间开展了一项回顾性队列研究,研究对象包括接受过手术治疗的温哥华B2和B3骨折患者。患者被分为非骨水泥和骨水泥柄翻修组,并收集了有关并发症、翻修手术、骨折愈合时间和临床效果的数据:结果:共确定了241名患者。两组患者在人口统计学方面存在显著差异,骨水泥组患者年龄较大,女性较多。随访时间从 1 年到 15 年不等。骨水泥植入组的平均随访时间为 3.9 年,非骨水泥植入组为 5.5 年。骨水泥基台脱位率(8.9%对22.5%,P = 0.004)和基台松动率(0.6%对9.3%,P = 0.004)均低于非骨水泥基台。此外,骨水泥组的骨折愈合时间更短(11.4周对16.7周,P = 0.034)。两组的临床结果没有差异。结论:这项回顾性研究表明,与非骨水泥方法相比,骨水泥干翻修治疗温哥华B2-3骨折的脱位率和干松动率较低,需要再次手术的次数较少,骨折愈合时间较短。骨水泥组的死亡率明显较高,因此在临床解释时需要谨慎:
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引用次数: 0
Comparing autologous blood, corticosteroid, and a combined injection of both for treating lateral epicondylitis: a randomized clinical trial. 比较自体血、皮质类固醇和两者联合注射治疗外侧上髁炎:随机临床试验。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-07-04 DOI: 10.1186/s10195-024-00772-4
Albert Cakar, Ozgur Dogus Gozlu

Background: Because lateral epicondylitis is a common musculoskeletal disorder that affects the forearm's extensor tendons, an effective therapeutic approach should reverse the degeneration and promote regeneration. This study aimed to compare the efficacies of autologous blood (AB) injection, corticosteroid (CS) injection, and a combined injection of both in treating lateral epicondylitis (LE), hypothesizing that the combined approach might offer immediate symptom resolution and a lower recurrence.

Materials and methods: A total of 120 patients diagnosed with lateral epicondylitis were systematically distributed among three distinct therapeutic injection groups. Those in the AB group were administered 1 ml of autologous venous blood mixed with 2 ml of 2% prilocaine HCl. Participants in the CS category were given 1 ml of 40 mg methylprednisolone acetate mixed with 2 ml of 2% prilocaine HCl. Meanwhile, patients in the combined group received a mixture containing 1 ml each of autologous venous blood and 40 mg methylprednisolone acetate along with 1 ml of 2% prilocaine HCl. Prior to receiving their respective injections, a comprehensive assessment of all participants was carried out. Follow-up assessments were subsequently conducted on days 15, 30, and 90 utilizing metrics of the patient-rated tennis elbow evaluation (PRTEE) and measurements of hand grip strength (HGS).

Results: One patient dropped out from the combined group, and 119 patients completed the trial. No complications were recorded during the course of follow-up. By day 15, all groups had demonstrated significant PRTEE improvement, with CS showing the most pronounced reduction (p = 0.001). However, the benefits of CS had deteriorated by day 30 and had deteriorated further by day 90. The AB and AB + CS groups demonstrated sustained improvement, with AB + CS revealing the most effective treatment, achieving a clinically significant improvement in 97.4% of the patients. The improved HGS parallelled the functional enhancements, as it was more substantial in the AB and AB + CS groups (p = 0.001), corroborating the sustained benefits of these treatments.

Conclusions: The study concluded that while AB and CS individually offer distinct benefits, a combined AB + CS approach optimizes therapeutic outcomes, providing swift and sustained functional improvement with a lower recurrence rate. These findings have substantial clinical implications, suggesting a balanced, multimodal treatment strategy for enhanced patient recovery in LE.

Level of evidence: Randomized clinical trial, level 1 evidence.

Trial registration: NCT06236178.

背景:外上髁炎是一种影响前臂伸肌腱的常见肌肉骨骼疾病,因此有效的治疗方法应能逆转外上髁肌腱的退化并促进其再生。本研究旨在比较自体血(AB)注射、皮质类固醇(CS)注射以及两者联合注射治疗外侧上髁炎(LE)的疗效,假设联合治疗可立即缓解症状并降低复发率:将 120 名确诊为外侧上髁炎的患者系统地分配到三个不同的治疗注射组。AB组患者注射1毫升自体静脉血和2毫升2%盐酸普鲁卡因。CS组患者注射1毫升40毫克醋酸甲泼尼龙和2毫升2%盐酸普鲁卡因。与此同时,混合组的患者则注射了各含 1 毫升自体静脉血和 40 毫克醋酸甲泼尼龙以及 1 毫升 2% 盐酸普鲁卡因的混合物。在接受注射前,对所有参与者进行了全面评估。随后在第 15、30 和 90 天进行了随访评估,评估采用了患者评定的网球肘评估指标(PRTEE)和手部握力测量指标(HGS):结果:联合组中有一名患者退出,119 名患者完成了试验。随访期间未出现并发症。到第 15 天,所有组的 PRTEE 均有显著改善,其中 CS 的改善最为明显(p = 0.001)。然而,CS 的疗效在第 30 天时有所下降,在第 90 天时进一步恶化。AB 组和 AB + CS 组显示出持续的改善,其中 AB + CS 显示出最有效的治疗方法,97.4% 的患者获得了显著的临床改善。HGS 的改善与功能的增强同步,因为 AB 组和 AB + CS 组的改善幅度更大(p = 0.001),这证实了这些治疗方法的持续疗效:该研究得出结论:虽然 AB 和 CS 单独治疗具有不同的益处,但 AB + CS 联合治疗可优化治疗效果,迅速、持续地改善功能,降低复发率。这些研究结果具有重要的临床意义,提出了一种平衡、多模式的治疗策略,以促进 LE 患者的康复:随机临床试验,1级证据:试验注册:NCT06236178。
{"title":"Comparing autologous blood, corticosteroid, and a combined injection of both for treating lateral epicondylitis: a randomized clinical trial.","authors":"Albert Cakar, Ozgur Dogus Gozlu","doi":"10.1186/s10195-024-00772-4","DOIUrl":"10.1186/s10195-024-00772-4","url":null,"abstract":"<p><strong>Background: </strong>Because lateral epicondylitis is a common musculoskeletal disorder that affects the forearm's extensor tendons, an effective therapeutic approach should reverse the degeneration and promote regeneration. This study aimed to compare the efficacies of autologous blood (AB) injection, corticosteroid (CS) injection, and a combined injection of both in treating lateral epicondylitis (LE), hypothesizing that the combined approach might offer immediate symptom resolution and a lower recurrence.</p><p><strong>Materials and methods: </strong>A total of 120 patients diagnosed with lateral epicondylitis were systematically distributed among three distinct therapeutic injection groups. Those in the AB group were administered 1 ml of autologous venous blood mixed with 2 ml of 2% prilocaine HCl. Participants in the CS category were given 1 ml of 40 mg methylprednisolone acetate mixed with 2 ml of 2% prilocaine HCl. Meanwhile, patients in the combined group received a mixture containing 1 ml each of autologous venous blood and 40 mg methylprednisolone acetate along with 1 ml of 2% prilocaine HCl. Prior to receiving their respective injections, a comprehensive assessment of all participants was carried out. Follow-up assessments were subsequently conducted on days 15, 30, and 90 utilizing metrics of the patient-rated tennis elbow evaluation (PRTEE) and measurements of hand grip strength (HGS).</p><p><strong>Results: </strong>One patient dropped out from the combined group, and 119 patients completed the trial. No complications were recorded during the course of follow-up. By day 15, all groups had demonstrated significant PRTEE improvement, with CS showing the most pronounced reduction (p = 0.001). However, the benefits of CS had deteriorated by day 30 and had deteriorated further by day 90. The AB and AB + CS groups demonstrated sustained improvement, with AB + CS revealing the most effective treatment, achieving a clinically significant improvement in 97.4% of the patients. The improved HGS parallelled the functional enhancements, as it was more substantial in the AB and AB + CS groups (p = 0.001), corroborating the sustained benefits of these treatments.</p><p><strong>Conclusions: </strong>The study concluded that while AB and CS individually offer distinct benefits, a combined AB + CS approach optimizes therapeutic outcomes, providing swift and sustained functional improvement with a lower recurrence rate. These findings have substantial clinical implications, suggesting a balanced, multimodal treatment strategy for enhanced patient recovery in LE.</p><p><strong>Level of evidence: </strong>Randomized clinical trial, level 1 evidence.</p><p><strong>Trial registration: </strong>NCT06236178.</p>","PeriodicalId":48603,"journal":{"name":"Journal of Orthopaedics and Traumatology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11224188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic evaluation of robot-assisted versus manual total hip arthroplasty: a multicenter randomized controlled trial. 机器人辅助与人工全髋关节置换术的放射学评估:多中心随机对照试验。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-06-26 DOI: 10.1186/s10195-024-00773-3
Xianzuo Zhang, Xianyue Shen, Rongwei Zhang, Mo Chen, Ruixiang Ma, Zian Zhang, Haining Zhang, Bo Yang, Chen Zhu

Background: The effectiveness of robot-assisted surgery remains contentious due to the lack of high-quality randomized controlled trials (RCTs) to elevate the level of evidence. We aimed to evaluate the postoperative radiographic outcomes of robot-assisted (RAS-THA) versus manual (M-THA) total hip arthroplasty.

Methods: This multicenter RCT was performed from March 1, 2021 to December 1, 2021. Patients were randomly assigned to routine M-THA or to RAS-THA that used the TRex-RS orthopedic joint surgical navigation system. The primary outcome was to compare the acetabular component orientation, femoral stem alignment, femoral canal fill ratio, and leg length discrepancy between RAS-THA and M-THA using postoperative radiography. Subgroup analyses of the two groups stratified by surgical approach, gender, and BMI were also conducted.

Results: Seventy-three participants were randomly allocated to the RAS-THA group, while seventy-two participants were assigned to the M-THA group. Compared to the M-THA group, the RAS-THA group exhibited less variability in the preoperative planning of the vertical center of rotation (VCOR; P < 0.001), demonstrated a significant advantage in femoral stem alignment (P = 0.004), and showed pronounced decreases in inequality and in the variability in leg length discrepancy (P < 0.001). There was no significant difference in the Lewinnek safe-zone ratio (P = 0.081) and the femoral canal fill ratio (P > 0.05) between the two groups. Further subgroup analysis also showed that the RAS-THA group had fewer horizontal center of rotation (HCOR) and leg length differences when stratified by surgical approach, gender, and overweight status.

Conclusion: This RCT found that, regardless of the surgical approach, gender, or body mass index, RAS-THA can effectively improve the postoperative VCOR and significantly reduce the variability of leg length difference. RAS-THA should be considered an effective method to enhance surgical precision by achieving less variability in challenging patients with leg length discrepancies.

Trial registration: ChiCTR2100044124.

背景:由于缺乏高质量的随机对照试验(RCT)来提高证据水平,机器人辅助手术的有效性仍存在争议。我们旨在评估机器人辅助(RAS-THA)与人工(M-THA)全髋关节置换术的术后放射学结果:这项多中心 RCT 于 2021 年 3 月 1 日至 2021 年 12 月 1 日进行。患者被随机分配到常规M-THA或使用TRex-RS骨科关节手术导航系统的RAS-THA。主要结果是比较RAS-THA和M-THA术后X光片显示的髋臼组件方向、股骨干排列、股骨管填充率和腿长差异。此外,还按手术方法、性别和体重指数对两组进行了分组分析:73名参与者被随机分配到RAS-THA组,72名参与者被分配到M-THA组。与M-THA组相比,RAS-THA组在术前规划垂直旋转中心(VCOR;P 0.05)时两组间的差异较小。进一步的亚组分析还显示,根据手术方式、性别和超重状况进行分层后,RAS-THA组的水平旋转中心(HCOR)和腿长差异较小:这项研究发现,无论手术方式、性别或体重指数如何,RAS-THA 都能有效改善术后 VCOR,并显著减少腿长差异的变化。对于具有挑战性的腿长不一致患者,RAS-THA应被视为通过减少变异性来提高手术精确度的有效方法:ChiCTR2100044124。
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引用次数: 0
Effect of different lumbar-iliac fixation and sacral slope for Tile C1.3 pelvic fractures: a biomechanical study. 不同的腰髂固定和骶骨斜度对 Tile C1.3 骨盆骨折的影响:一项生物力学研究。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2024-06-26 DOI: 10.1186/s10195-024-00776-0
Shicai Fan, Hongjie Luo, Sheqiang Chen, Haibo Xiang, Qiguang Mai, Zhenhua Zhu, Yuhui Chen, Zhiyong Hou, Wei Chen, Qingan Zhu, Yingze Zhang

Background: Lumbar-iliac fixation (LIF) is a common treatment for Tile C1.3 pelvic fractures, but different techniques, including L4-L5/L5 unilateral LIF (L4-L5/L5 ULIF), bilateral LIF (BLIF), and L4-L5/L5 triangular osteosynthesis (L4-L5/L5 TOS), still lack biomechanical evaluation. The sacral slope (SS) is key to the vertical shear of the sacrum but has not been investigated for its biomechanical role in lumbar-iliac fixation. The aim of this study is to evaluate the biomechanical effects of different LIF and SS on Tile C1.3 pelvic fracture under two-legged standing load in human cadavers.

Methods: Eight male fresh-frozen human lumbar-pelvic specimens were used in this study. Compressive force of 500 N was applied to the L4 vertebrae in the two-legged standing position of the pelvis. The Tile C1.3 pelvic fracture was prepared, and the posterior pelvic ring was fixed with L5 ULIF, L4-L5 ULIF, L5 TOS, L4-L5 TOS, and L4-L5 BLIF, respectively. Displacement and rotation of the anterior S1 foramen at 30° and 40° sacral slope (SS) were analyzed.

Results: The displacement of L4-L5/L5 TOS in the left-right and vertical direction, total displacement, and rotation in lateral bending decreased significantly, which is more pronounced at 40° SS. The difference in stability between L4-L5 and L5 ULIF was not significant. BLIF significantly limited left-right displacement. The ULIF vertical displacement at 40° SS was significantly higher than that at 30° SS.

Conclusions: This study developed an in vitro two-legged standing pelvic model and demonstrated that TOS enhanced pelvic stability in the coronal plane and cephalad-caudal direction, and BLIF enhanced stability in the left-right direction. L4-L5 ULIF did not further improve the immediate stability, whereas TOS is required to increase the vertical stability at greater SS.

背景:腰髂固定术(LIF)是治疗Tile C1.3骨盆骨折的常用方法,但包括L4-L5/L5单侧LIF(L4-L5/L5 ULIF)、双侧LIF(BLIF)和L4-L5/L5三角骨合成术(L4-L5/L5 TOS)在内的不同技术仍缺乏生物力学评估。骶骨斜坡(SS)是骶骨垂直剪切力的关键,但尚未对其在腰髂固定中的生物力学作用进行研究。本研究旨在评估不同 LIF 和 SS 在人体尸体两腿站立负荷下对 Tile C1.3 骨盆骨折的生物力学影响:方法:本研究使用了 8 具男性新鲜冷冻人体腰椎骨盆标本。在骨盆两腿站立姿势下,对 L4 椎体施加 500 N 的压缩力。制备 Tile C1.3 骨盆骨折,并分别用 L5 ULIF、L4-L5 ULIF、L5 TOS、L4-L5 TOS 和 L4-L5 BLIF 固定骨盆后环。分析了骶骨斜度(SS)为30°和40°时S1前孔的移位和旋转情况:结果:L4-L5/L5 TOS在左右方向和垂直方向的位移、总位移和侧弯时的旋转均明显减少,在骶骨斜度为40°时更为明显。L4-L5 和 L5 ULIF 的稳定性差异不明显。BLIF 明显限制了左右位移。40°SS时的ULIF垂直位移明显高于30°SS时:本研究建立了一个体外双腿站立骨盆模型,并证明TOS可增强骨盆在冠状面和头尾方向的稳定性,而BLIF可增强左右方向的稳定性。L4-L5 ULIF 不能进一步提高即时稳定性,而 TOS 则需要在更大的 SS 上提高垂直稳定性。
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引用次数: 0
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Journal of Orthopaedics and Traumatology
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