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Impact of systemic lupus erythematosus on adverse outcomes and readmission after total shoulder arthroplasty: a Nationwide Readmission Database analysis 2016-2020. 系统性红斑狼疮对全肩关节置换术后不良结局和再入院的影响:2016-2020年全国再入院数据库分析
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-06-21 DOI: 10.1186/s10195-025-00858-7
Hao-Ming Chang, Tzu-Hao Wang

Background: The impact of systemic lupus erythematosus (SLE) on total shoulder arthroplasty (TSA) outcomes is unclear. This study investigated the association between SLE and short-term TSA outcomes.

Methods: Data from the Nationwide Readmission Database (NRD) 2016-2020 of patients ≥ 20 years old who underwent primary TSA were included. SLE was identified by International Classification of Diseases, Tenth Revision, and Clinical Modification (ICD-10-CM) codes. Outcomes were compared between patients with and without SLE, and propensity-score matching based on age and sex was performed.

Results: This study included 1960 matched TSA patients (980 with SLE and 980 without SLE). The mean patient age was 65.7 years, and 92% were female. After adjusting for covariates, SLE was significantly associated with a higher risk of surgical complications (odds ratio [OR] = 1.48, 95% confidence interval [CI]: 1.13-1.93), acute postoperative hemorrhagic anemia (OR = 1.48, 95% CI 1.05-2.09), and increased 30-day (OR = 2.11, 95% CI 1.30-3.40) and 90-day (OR = 1.59, 95% CI 1.11-2.26) readmission rates. Patients with SLE with Charlson Comorbidity Index scores of 0 or > 1 had a significantly higher 90-day readmission rate (OR = 2.45 and 1.48, respectively). Additionally, patients with SLE ≥ 65 years old had a significantly higher risk of complications (OR = 1.56). Patients with SLE undergoing reverse TSA also exhibited a significantly increased 90-day readmission risk (OR = 1.71).

Conclusions: SLE significantly increases the risk of postoperative complications and readmissions following TSA, especially in older patients and those undergoing reverse TSA. However, the lack of data on immunosuppressive therapy, laboratory tests, and disease activity may weaken the strength of the evidence.

背景:系统性红斑狼疮(SLE)对全肩关节置换术(TSA)结果的影响尚不清楚。这项研究调查了SLE和短期TSA结果之间的关系。方法:纳入2016-2020年全国再入院数据库(NRD)中接受原发性TSA的≥20岁患者的数据。SLE通过国际疾病分类第十版和临床修改(ICD-10-CM)代码进行鉴定。比较了SLE患者和非SLE患者的结果,并进行了基于年龄和性别的倾向评分匹配。结果:本研究纳入1960例匹配的TSA患者(980例合并SLE, 980例未合并SLE)。患者平均年龄为65.7岁,92%为女性。调整协变量后,SLE与较高的手术并发症风险(优势比[OR] = 1.48, 95%可信区间[CI]: 1.13-1.93)、急性术后出血性贫血(OR = 1.48, 95% CI 1.05-2.09)以及增加的30天(OR = 2.11, 95% CI 1.30-3.40)和90天(OR = 1.59, 95% CI 1.11-2.26)再入院率显著相关。Charlson合并症指数评分为0或>.1的SLE患者90天再入院率明显较高(or分别为2.45和1.48)。此外,年龄≥65岁的SLE患者发生并发症的风险明显更高(OR = 1.56)。接受反向TSA的SLE患者也显示出90天再入院风险显著增加(OR = 1.71)。结论:SLE显著增加TSA术后并发症和再入院的风险,特别是在老年患者和逆行TSA的患者中。然而,缺乏免疫抑制治疗、实验室测试和疾病活动的数据可能会削弱证据的强度。
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引用次数: 0
What influences the surgeon's decision between anatomical and reverse total shoulder arthroplasty in primary osteoarthritis? A case-vignette study. 在原发性骨关节炎中,是什么影响了外科医生在解剖和反向全肩关节置换术之间的选择?个案研究。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-06-04 DOI: 10.1186/s10195-025-00854-x
Dries Boulidam, Arno A Macken, Tim Kraal, Tjarco D W Alta, Michel P J van den Bekerom, Laurent Lafosse, Thibault Lafosse, Geert A Buijze

Background: Historically, anatomical total shoulder arthroplasty (ATSA) has been the standard intervention for primary osteoarthritis in patients with an intact rotator cuff. However, there is an increasing trend towards utilizing reverse total shoulder arthroplasty (RTSA) as an alternative in specific cases. The aim of this study is to investigate the influence of the degree of retroversion, percentage of subluxation and age on the surgeon's decision-making in the choice between ATSA and RTSA in patients with primary osteoarthritis with an intact rotator cuff.

Methods: Attendees of a large international congress on (live) shoulder surgery were requested to complete a questionnaire consisting of closed and open questions regarding shoulder arthroplasty and clinical scenarios. Participants were divided into high- and low-volume surgeons (< 30 cases per year).

Results: A total of 166 responses were collected. In total, 37 different nationalities from all six continents were represented among the respondents. The included participants had a median experience of 11 years (interquartile range, IQR: 6-18). In total, 56 (39%) participants were considered high-volume surgeons. The median degree of retroversion, the median percentage of posterior subluxation and the median age for which participants still considered performing ATSA rather than RTSA were respectively 20° (IQR: 10-20.75), 70% (IQR: 60-80) and 70 years (IQR: 65-75). Furthermore, a low degree of consensus was observed for the choice of treatment in the ten case vignettes with these factors combined. In case of significant disagreement, RTSA was preferred more often by high-volume surgeons compared with low-volume surgeons.

Conclusions: This case-vignette study highlights that the degree of retroversion, percentage of subluxation of the humeral head and the patient's age are important factors to consider in the surgeon's decision-making between ATSA and RTSA. However, our findings indicate limited consensus among orthopaedic surgeons concerning the precise impact of these patient-specific factors. Despite the lack of consensus, some trends can be identified. Overall, participants preferred treatment with RTSA in patients with a high degree of retroversion and older age. Treatment with ATSA was preferred in patients with a younger age, without severe glenoid retroversion and a posterior subluxation of < 80%. The level of evidence is Level V, expert opinion.

背景:历史上,解剖学全肩关节置换术(ATSA)一直是治疗肩袖完整患者原发性骨关节炎的标准干预措施。然而,有越来越多的趋势,在特定情况下,使用反向全肩关节置换术(RTSA)作为替代方案。本研究的目的是探讨对肩袖完整的原发性骨关节炎患者进行ATSA和RTSA手术时,手术后退程度、半脱位百分比和年龄对外科医生决策的影响。方法:一个大型国际会议(现场)肩部手术的与会者被要求完成一份问卷,包括关于肩关节置换术和临床场景的封闭式和开放式问题。参与者被分为高容量和低容量的外科医生(结果:共收集了166份回复。总共有来自六大洲的37个不同国家的受访者。纳入的参与者的平均经历为11年(四分位数范围,IQR: 6-18)。总共有56名(39%)参与者被认为是大容量外科医生。参与者仍然考虑进行ATSA而非RTSA的中位退位度、后半脱位的中位百分比和中位年龄分别为20°(IQR: 10-20.75)、70% (IQR: 60-80)和70岁(IQR: 65-75)。此外,在这些因素结合的10例病例中,观察到治疗选择的共识程度较低。在有明显分歧的情况下,大容量外科医生比小容量外科医生更倾向于RTSA。结论:本病例-小片段研究强调,在外科医生选择ATSA还是RTSA时,肱骨后移程度、肱骨头半脱位百分比和患者年龄是重要的考虑因素。然而,我们的研究结果表明,骨科医生对这些患者特异性因素的确切影响的共识有限。尽管缺乏共识,但可以确定一些趋势。总体而言,参与者更倾向于在高度逆行和年龄较大的患者中使用RTSA治疗。对于年龄较小、没有严重关节盂后翻和关节后半脱位的患者,首选ATSA治疗
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引用次数: 0
Risk factors for surgical site infection following treatment of proximal femoral fracture: a matched-pair analysis. 股近端骨折治疗后手术部位感染的危险因素:配对分析。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-06-04 DOI: 10.1186/s10195-025-00856-9
Franz Müller, Michael Zellner, Christian Bäuml, Andreas Proske, Bernd Füchtmeier, Christian Wulbrand

Background: Surgical site infection (SSI) is a major postoperative complication following internal fixation or arthroplasty for proximal femoral fracture (PFF). Few studies have examined the potential risk factors for SSI; therefore, we conducted this matched-pair analysis.

Materials and methods: This single-centre study was based on a retrospective database of patients treated for PFF with internal fixation or arthroplasty between 2006 and 2024. Patients with revision for SSI were enrolled and matched with an uneventfully treated group at a 1:3 ratio. Matching was performed on the basis of sex, age, body mass index, diagnosis and treatment. The primary outcomes were risk factors for SSI. The secondary outcomes were risk factors for mortality, as determined by multivariate Cox regression analysis.

Results: Initially, a total of 5000 patients were enrolled. The mean follow-up was 11.7 years. The total SSI rate was 2.8% (140/5,000). Ultimately, 130 patients with confirmed SSI and 390 matched patients were enrolled in this study. Most of the SSIs were Staphylococcus aureus, followed by Staphylococcus epidermidis. The factors that significantly influenced SSI were female sex, American Society of Anaesthesiologists (ASA) score of 4, dementia, atrial fibrillation, and the number of red blood transfusions (≥ 3 units). The mean survival duration of the total cohort was 4.2 years (SD ± 3.38). The 30-day, 3-month and 1-year all-cause mortality rates of patients with SSIs were 5.4%, 25.4%, and 40%, respectively. Multivariate Cox regression revealed that SSI was an independent risk factor for mortality (hazard ratio 1.59; 95% confidence interval 1.28-1.98; p < 0.001), Further risk factors for mortality were living in a retirement home, reduced mobility, anaemia at admission, elevated C-reactive protein, ASA score 3 or 4, intraoperative blood loss greater than 400 ml, Charlson comorbidity index score above ≥ 1, dementia and renal insufficiency.

Conclusions: In this study, patients with SSI following surgery of PFF had a significantly shorter survival time than patients in the uneventfully treated matched-pair group. Most risk factors associated with SSI are unaffected. Fortunately, the rate of SSI was low and decreased significantly within the study period.

Lever of evidence: III; clinical case series with matched pair controls.

背景:手术部位感染(SSI)是股骨近端骨折(PFF)内固定或关节置换术后的主要并发症。很少有研究检查了SSI的潜在危险因素;因此,我们进行了配对分析。材料和方法:这项单中心研究基于2006年至2024年间接受内固定或关节置换术治疗的PFF患者的回顾性数据库。对SSI进行翻修的患者被纳入,并以1:3的比例与平稳治疗组配对。根据性别、年龄、体重指数、诊断和治疗情况进行匹配。主要结局是SSI的危险因素。次要结局是死亡率的危险因素,由多变量Cox回归分析确定。结果:最初,共有5000名患者入组。平均随访时间为11.7年。总SSI率为2.8%(140/ 5000)。最终,130例确诊SSI患者和390例匹配患者被纳入本研究。ssi以金黄色葡萄球菌为主,其次为表皮葡萄球菌。影响SSI的因素有女性、美国麻醉学会(ASA)评分4分、痴呆、心房颤动、红血球输注次数(≥3个单位)。整个队列的平均生存时间为4.2年(SD±3.38)。ssi患者30天、3个月和1年的全因死亡率分别为5.4%、25.4%和40%。多因素Cox回归显示SSI是死亡的独立危险因素(危险比1.59;95%置信区间1.28-1.98;p结论:在本研究中,PFF术后SSI患者的生存时间明显短于平稳治疗配对组患者。大多数与SSI相关的危险因素未受影响。幸运的是,SSI的发生率很低,并且在研究期间显著下降。证据级别:III;配对对照的临床病例系列。
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引用次数: 0
Reduction and outcome of posterior pilon fractures with intercalary fragments: a retrospective cohort study comparing the transfibular and posteromedial approaches. 后枕骨骨折伴骨间碎片的复位和预后:一项比较经腓骨入路和后内侧入路的回顾性队列研究。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-05-29 DOI: 10.1186/s10195-025-00851-0
Li Ying, Can Yao, Bin Wang, Junbo Liang, Guofu Chen

Background: The transfibular fracture region (TFFR) approach can be utilized for managing posterior pilon fractures associated with intercalary fragments. However, its long-term outcomes remain unreported. This study aimed to compare the long-term clinical outcomes of the TFFR approach and the posteromedial approach for posterior pilon fractures (Klammer type 2/3, Danis-Weber type B) associated with displaced intercalary fragments over an average 8 year follow-up.

Method: From 2012 to 2018, a cohort of consecutive patients who underwent open reduction and internal fixation surgery via either the TFFR approach or the posteromedial approach for posterior pilon fracture associated with intercalary fragments were enrolled for this study. Clinical outcomes were evaluated over an average 8 year (range 5-12 years) follow-up. The surgical duration, number of intraoperative fluoroscopies, and postoperative complications were recorded. Functional outcomes were assessed using the Foot and Ankle Outcome Score (FAOS), Foot and Ankle Ability Measure (FAAM), and Short Form-36 (SF-36) score at last follow-up.

Results: Seventy-nine patients were included in the final analysis, including 43 in the TFFR group and 36 in the posteromedial group. No significant differences between the two groups were observed in the FAOS (p = 0.679) or its specific components for symptoms (p = 0.264), pain (p = 0.963), activities of daily living (ADL, p = 0.102), sports (p = 0.156), or quality of life (p = 0.859). There was also no significant difference between the two groups in the FAAM-ADL (p = 0.408), FAAM-Sport (p = 0.617), and SF-36 scores (p = 0.757). Nevertheless, the surgical duration was shorter in the TFFR group (p < 0.001).

Conclusion: The TFFR approach is not inferior to the posteromedial approach. For posterior pilon fractures with lateral malleolar fractures in the same plane, the TFFR approach may be preferred owing to its potential to reduce surgical time and the use of a single incision. Level of Evidence Level III, retrospective cohort study.

背景:经腓骨骨折区(TFFR)入路可用于治疗伴有骨间碎片的后pilon骨折。然而,其长期结果仍未报告。本研究旨在比较TFFR入路和后内侧入路治疗伴有移位的鞍后骨折(Klammer 2/3型,Danis-Weber B型)的长期临床结果,平均随访8年。方法:从2012年到2018年,连续入组通过TFFR入路或后内侧入路接受切开复位内固定手术治疗后皮隆骨折伴鞍间碎片的患者。临床结果评估平均8年(范围5-12年)的随访。记录手术时间、术中透视次数及术后并发症。在最后随访时,使用足踝结局评分(FAOS)、足踝能力测量(FAAM)和短表36 (SF-36)评分评估功能结局。结果:最终纳入79例患者,其中TFFR组43例,后内侧组36例。两组患者在FAOS评分(p = 0.679)或其症状(p = 0.264)、疼痛(p = 0.963)、日常生活活动(ADL, p = 0.102)、运动(p = 0.156)或生活质量(p = 0.859)方面均无显著差异。两组间FAAM-ADL评分(p = 0.408)、FAAM-Sport评分(p = 0.617)、SF-36评分(p = 0.757)也无显著差异。然而,TFFR组的手术时间较短(p)。结论:TFFR入路并不逊色于后内侧入路。对于后pilon骨折合并外踝骨折在同一平面,TFFR入路可能是首选,因为它有可能减少手术时间和使用单一切口。证据水平III级,回顾性队列研究。
{"title":"Reduction and outcome of posterior pilon fractures with intercalary fragments: a retrospective cohort study comparing the transfibular and posteromedial approaches.","authors":"Li Ying, Can Yao, Bin Wang, Junbo Liang, Guofu Chen","doi":"10.1186/s10195-025-00851-0","DOIUrl":"10.1186/s10195-025-00851-0","url":null,"abstract":"<p><strong>Background: </strong>The transfibular fracture region (TFFR) approach can be utilized for managing posterior pilon fractures associated with intercalary fragments. However, its long-term outcomes remain unreported. This study aimed to compare the long-term clinical outcomes of the TFFR approach and the posteromedial approach for posterior pilon fractures (Klammer type 2/3, Danis-Weber type B) associated with displaced intercalary fragments over an average 8 year follow-up.</p><p><strong>Method: </strong>From 2012 to 2018, a cohort of consecutive patients who underwent open reduction and internal fixation surgery via either the TFFR approach or the posteromedial approach for posterior pilon fracture associated with intercalary fragments were enrolled for this study. Clinical outcomes were evaluated over an average 8 year (range 5-12 years) follow-up. The surgical duration, number of intraoperative fluoroscopies, and postoperative complications were recorded. Functional outcomes were assessed using the Foot and Ankle Outcome Score (FAOS), Foot and Ankle Ability Measure (FAAM), and Short Form-36 (SF-36) score at last follow-up.</p><p><strong>Results: </strong>Seventy-nine patients were included in the final analysis, including 43 in the TFFR group and 36 in the posteromedial group. No significant differences between the two groups were observed in the FAOS (p = 0.679) or its specific components for symptoms (p = 0.264), pain (p = 0.963), activities of daily living (ADL, p = 0.102), sports (p = 0.156), or quality of life (p = 0.859). There was also no significant difference between the two groups in the FAAM-ADL (p = 0.408), FAAM-Sport (p = 0.617), and SF-36 scores (p = 0.757). Nevertheless, the surgical duration was shorter in the TFFR group (p < 0.001).</p><p><strong>Conclusion: </strong>The TFFR approach is not inferior to the posteromedial approach. For posterior pilon fractures with lateral malleolar fractures in the same plane, the TFFR approach may be preferred owing to its potential to reduce surgical time and the use of a single incision. Level of Evidence Level III, retrospective cohort study.</p>","PeriodicalId":48603,"journal":{"name":"Journal of Orthopaedics and Traumatology","volume":"26 1","pages":"34"},"PeriodicalIF":3.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel augmentation technique for the repair of full thickness gluteal tendon tears: a biomechanical analysis in an ovine model. 一种用于修复全层臀肌腱撕裂的新型增强技术:羊模型的生物力学分析。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-05-24 DOI: 10.1186/s10195-025-00850-1
Alexander Derksen, Zarife Balli, Henning Windhagen, Dennis Nebel, Janin Reifenrath

Background: Gluteus medius tendon tears lead to considerable functional limitations and a high level of suffering in affected patients. In cases where the symptoms are severe, surgical intervention is indicated. A range of techniques are used to repair the tendon, with the primary aim being to achieve the highest possible primary stability in order to minimise the risk of re-rupture. This biomechanical study compares two different refixation techniques in terms of their stability in an ovine model.

Material and methods: The gluteal tendons of sheep hips (n = 17) were meticulously prepared and detached from the femoral insertion. To reattach these tendons at their original anatomical footprint, either the sole double-row transosseous-equivalent technique (DR) or the DR supplemented by a proximal suture insertion (augmentation) of the tendon (DR +) was used. Pull-out tests were performed until failure using a uniaxial material testing machine, with a tensile force applied along the physiological tensile direction of the hip abductors. The data obtained (force at failure, linear stiffness) were compared between the groups using the Mann-Whitney U test.

Results: The augmentation of the proximal tendon portion resulted in a substantial increase in force at failure, exceeding 450% (698 ± 80.3 N DR + compared with 155.9 ± 53.9 N DR technique). In addition, augmented tendons exhibited a notable enhancement in stiffness, with an average increase of 31.3 ± 15 N/mm in DR + compared with 12.4 ± 4.8 N/mm in DR. Furthermore, the DR + method resulted in a substantial reduction in the incidence of slippage of the tendon fibres out of the sutures and tendon bundles when compared with the DR suture.

Conclusions: The clinical problem of suture knots becoming loose within the tendon stump, leading to the failure of the tendon sutures, could be mitigated by additional augmentation, resulting in a substantial increase in ultimate load at failure. The benefits of the double-row transosseous-equivalent technique, which facilitates the pressing of the tendon stump against the footprint, are maintained. Level of Evidence Level of Evidence 5.

背景:臀中肌腱撕裂会导致相当大的功能限制和患者的高度痛苦。在症状严重的情况下,需要手术干预。使用一系列技术来修复肌腱,主要目的是达到尽可能高的初级稳定性,以尽量减少再次断裂的风险。这项生物力学研究比较了两种不同的再固定技术在羊模型中的稳定性。材料和方法:羊臀肌腱(n = 17)精心制备并从股止点分离。为了在其原始解剖足迹处重新连接这些肌腱,使用鞋底双排经骨等效技术(DR)或DR补充近端肌腱缝线插入(增强)(DR +)。使用单轴材料试验机进行拔出试验直到失效,拉伸力沿髋关节外展肌的生理拉伸方向施加。所获得的数据(破坏时的力,线性刚度)使用Mann-Whitney U测试在两组之间进行比较。结果:近端肌腱部分的增加导致失败时的力大幅增加,超过450%(698±80.3 N DR +与155.9±53.9 N DR技术相比)。此外,增强肌腱的刚度显著增强,DR +平均增加31.3±15 N/mm,而DR +平均增加12.4±4.8 N/mm。此外,与DR缝合相比,DR +方法显著减少了肌腱纤维从缝合线和肌腱束中滑脱的发生率。结论:肌腱残端缝合结松动导致肌腱缝合失败的临床问题可以通过额外的增强来缓解,从而导致失败时的极限负荷大幅增加。双排跨骨等效技术的好处,有利于肌腱残端对足迹的压迫,被保持。证据级别证据级别
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引用次数: 0
Suture tape augmentation in the management of anterior cruciate ligament ruptures: a systematic review and meta-analysis. 缝合带增强治疗前交叉韧带断裂:系统回顾和荟萃分析。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-05-24 DOI: 10.1186/s10195-025-00845-y
Peiyuan Tang, Yangbin Cao, Ying Zhu, Han Tan, Haoxuan Li, Wenfeng Xiao, Ting Wen, Jun Zhang, Yusheng Li, Shuguang Liu

Background: The employment of suture tape augmentation (SA) in surgical interventions for anterior cruciate ligament (ACL) ruptures is a subject of ongoing debate. This meta-analysis synthesizes prior research to assess the effectiveness of additional SA in treating ACL tears.

Methods: A total of four databases including PubMed, Embase, Cochrane Library, and Web of Science were searched up to September 2024. Literature screening, quality evaluation, and data extraction were performed according to inclusion and exclusion criteria. Key data extracted include: Lysholm Knee Scoring Scale, International Knee Documentation Committee Score (IKDC), self-assessment numerical evaluation (SANE), Tegner Activity Score, Knee Injury and Osteoarthritis Outcome Score (KOOS), Veterans RAND 12-Item Health Survey (VR-12), Marx Activity Scale, visual analog scale (VAS), KT-1000 anteroposterior knee laxity, and return to sports rate. Meta-analysis of outcome indicators was performed using Revman 5.4 software.

Results: A total of 17 articles were included in this meta-analysis. Pre-post operation effect analysis showed that additional SA was correlated with improved IKDC, Marx Activity Scale, KOOS, VR-12 physical, and VAS for pain. In addition, there were statistically significant differences in SANE (mean difference, MD = 3.26, 95% confidence intervals, 95%CI 0.77, 5.76, P = 0.01, I2 = 13%) and VAS for pain (MD = -0.17, 95%CI -0.32, -0.02, P = 0.02, I2 = 0%) in the group using the SA technique compared with the traditional surgery group without SA. However, in terms of KT-1000 anteroposterior knee laxity, the traditional surgery group without SA was better than the group with SA (MD = 0.31, 95%CI 0.03, 0.59, P = 0.03, I2 = 0%).

Conclusions: On the basis of current evidence, we do not believe that, compared with isolated traditional surgical methods, additional SA can significantly improve patients' functional scores and help patients heal.

背景:缝合带增强(SA)在前交叉韧带(ACL)破裂手术干预中的应用是一个持续争论的主题。本荟萃分析综合了先前的研究,以评估额外SA治疗前交叉韧带撕裂的有效性。方法:检索截至2024年9月的PubMed、Embase、Cochrane Library、Web of Science 4个数据库。根据纳入和排除标准进行文献筛选、质量评价和资料提取。提取的关键数据包括:Lysholm膝关节评分量表、国际膝关节文献委员会评分(IKDC)、自评数值评价(SANE)、Tegner活动评分、膝关节损伤和骨关节炎结局评分(oos)、退伍军人RAND 12项健康调查(VR-12)、Marx活动量表、视觉模拟量表(VAS)、KT-1000前后位膝关节松弛度、恢复运动率。采用Revman 5.4软件对结局指标进行meta分析。结果:本meta分析共纳入17篇文章。手术前后效果分析显示,SA的增加与IKDC、Marx活动量表、oos、VR-12物理评分和疼痛VAS评分的改善相关。此外,使用SA技术组的SANE (mean difference, MD = 3.26, 95%可信区间,95% ci 0.77, 5.76, P = 0.01, I2 = 13%)和疼痛VAS (MD = -0.17, 95% ci -0.32, -0.02, P = 0.02, I2 = 0%)与不使用SA的传统手术组比较,差异均有统计学意义。但在KT-1000膝关节前后位松松度方面,未行SA的传统手术组优于SA组(MD = 0.31, 95%CI 0.03, 0.59, P = 0.03, I2 = 0%)。结论:根据目前的证据,我们不认为与孤立的传统手术方法相比,额外的SA可以显著提高患者的功能评分并帮助患者愈合。
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引用次数: 0
A meta-analysis of the therapeutic effect of total knee replacement after knee arthroscopic surgery. 膝关节镜手术后全膝关节置换术治疗效果的meta分析。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-05-22 DOI: 10.1186/s10195-025-00848-9
Yunwei Xu, Weidong Wang

Purpose: To appraise the influence of knee arthroscopic surgery on subsequent total knee arthroplasty (TKA) through meta-analysis.

Methods: A computer search was implemented from the establishment of the database to August 2023 for literature on the influence of knee arthroscopic surgery on the efficacy of subsequent TKA in Web of Science, PubMed, CNKI, Embase, Cochrane Library, Wanfang, and other databases. Quality assessment, literature screening, and data extraction were enforced according to the exclusion and inclusion criteria, and the methodological quality of the involved literature was assessed using the risk-of-bias assessment method recommended by the Cochrane Assistance Network. RevMan 5.4 software was used to conduct a meta-analysis on the postoperative revision rate, periprosthetic infection rate, postoperative stiffness rate, postoperative venous thromboembolism (VTE) incidence rate, reoperation rate, and postoperative knee flexion range of motion after TKA.

Results: Seven documents were finally involved, with a total of 42,642 cases, including 3405 cases in the knee arthroscopy group and 39,237 cases in the non-knee arthroscopy group. Meta-analysis results show that in the revision rate [95% confidence interval (CI) 0.97, 44.82] and reoperation rate [95% CI 1.66, 4.23] after TKA between the knee arthroscopy surgery group and the non-knee arthroscopy surgery group, there were statistically significant differences in postoperative stiffness rate [95% CI 0.86, 10.84] and periprosthetic infection rate [95% CI 0.86, 2.07], while in postoperative VTE incidence [95% CI 0.83, 1.35] and in postoperative knee flexion range of motion [95% CI -0.35, 0.10] there was no statistically significant difference.

Conclusions: Knee arthroscopic surgery hurts subsequent TKA surgery. Previous arthroscopic surgery increased the risk of postoperative stiffness, revision, periprosthetic infection, and reoperation after TKA, but there was no significant difference in the incidence of VTE and knee flexion range of motion after surgery.

目的:通过meta分析,评价膝关节镜手术对后续全膝关节置换术(TKA)的影响。方法:计算机检索Web of Science、PubMed、CNKI、Embase、Cochrane Library、万方等数据库中关于膝关节镜手术对后续TKA疗效影响的文献,自数据库建立至2023年8月。根据排除标准和纳入标准进行质量评估、文献筛选和数据提取,采用Cochrane辅助网络推荐的偏倚风险评估方法评估相关文献的方法学质量。采用RevMan 5.4软件对TKA术后翻修率、假体周围感染率、术后僵硬率、术后静脉血栓栓塞(venous thromboembolism, VTE)发生率、再手术率、术后膝关节屈曲活动度进行meta分析。结果:最终纳入7篇文献,共42642例,其中膝关节镜组3405例,非膝关节镜组39237例。meta分析结果显示,膝关节镜手术组与非膝关节镜手术组TKA术后翻修率[95%可信区间(CI) 0.97, 44.82]、再手术率[95% CI 1.66, 4.23],术后僵硬率[95% CI 0.86, 10.84]、假体周围感染率[95% CI 0.86, 2.07]差异有统计学意义;而术后静脉血栓栓塞发生率[95% CI 0.83, 1.35]和术后膝关节屈曲活动范围[95% CI -0.35, 0.10]差异无统计学意义。结论:膝关节镜手术对TKA术后有损伤。既往关节镜手术增加了术后僵硬、翻修、假体周围感染和TKA后再手术的风险,但术后VTE发生率和膝关节屈曲活动范围无显著差异。
{"title":"A meta-analysis of the therapeutic effect of total knee replacement after knee arthroscopic surgery.","authors":"Yunwei Xu, Weidong Wang","doi":"10.1186/s10195-025-00848-9","DOIUrl":"10.1186/s10195-025-00848-9","url":null,"abstract":"<p><strong>Purpose: </strong>To appraise the influence of knee arthroscopic surgery on subsequent total knee arthroplasty (TKA) through meta-analysis.</p><p><strong>Methods: </strong>A computer search was implemented from the establishment of the database to August 2023 for literature on the influence of knee arthroscopic surgery on the efficacy of subsequent TKA in Web of Science, PubMed, CNKI, Embase, Cochrane Library, Wanfang, and other databases. Quality assessment, literature screening, and data extraction were enforced according to the exclusion and inclusion criteria, and the methodological quality of the involved literature was assessed using the risk-of-bias assessment method recommended by the Cochrane Assistance Network. RevMan 5.4 software was used to conduct a meta-analysis on the postoperative revision rate, periprosthetic infection rate, postoperative stiffness rate, postoperative venous thromboembolism (VTE) incidence rate, reoperation rate, and postoperative knee flexion range of motion after TKA.</p><p><strong>Results: </strong>Seven documents were finally involved, with a total of 42,642 cases, including 3405 cases in the knee arthroscopy group and 39,237 cases in the non-knee arthroscopy group. Meta-analysis results show that in the revision rate [95% confidence interval (CI) 0.97, 44.82] and reoperation rate [95% CI 1.66, 4.23] after TKA between the knee arthroscopy surgery group and the non-knee arthroscopy surgery group, there were statistically significant differences in postoperative stiffness rate [95% CI 0.86, 10.84] and periprosthetic infection rate [95% CI 0.86, 2.07], while in postoperative VTE incidence [95% CI 0.83, 1.35] and in postoperative knee flexion range of motion [95% CI -0.35, 0.10] there was no statistically significant difference.</p><p><strong>Conclusions: </strong>Knee arthroscopic surgery hurts subsequent TKA surgery. Previous arthroscopic surgery increased the risk of postoperative stiffness, revision, periprosthetic infection, and reoperation after TKA, but there was no significant difference in the incidence of VTE and knee flexion range of motion after surgery.</p>","PeriodicalId":48603,"journal":{"name":"Journal of Orthopaedics and Traumatology","volume":"26 1","pages":"31"},"PeriodicalIF":3.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12098253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical timing and clinical factor predicting in-hospital mortality in older adults with hip fractures: a neuronal network analysis. 预测老年髋部骨折患者住院死亡率的手术时机和临床因素:神经网络分析。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-05-14 DOI: 10.1186/s10195-025-00846-x
Raffaele Vitiello, Elisa Pesare, Giacomo Capece, Emidio Di Gialleonardo, Andrea De Matthaeis, Francesco Franceschi, Giulio Maccauro, Marcello Covino
<p><strong>Introduction: </strong>Hip fractures in older adults are associated with a significant mortality rate, which has been reported to be around 35% within a year. Today, the incidence of these fractures is on the rise, and this trend is expected to increase even more owing to the aging of the population. Treatment timing and perioperative management of these patients are typically challenging owing to the presence of multiple comorbidities that are important risk factors for mortality after surgery. This study aims to evaluate the relationship between surgical timing and in-hospital mortality, analyzing the role of both acute events and chronic preexisting comorbidities in patient outcomes.</p><p><strong>Materials and methods: </strong>This is a single-center, retrospective observational study (from January 2018 until June 2023). All consecutive patients ≥ 65 years with a diagnosis of proximal femur fracture were enrolled. The primary study endpoint was to evaluate risk factors associated with in-hospital mortality. The secondary endpoint was the assessment of the relationship between surgical timing and in-hospital mortality, including factors such as preexisting comorbidities, the Charlson Comorbidity Index, and the Nottingham Hip Fracture Score. The relative weight of each factor for predicting the mortality rate was also evaluated using neural network analysis, comparing patients treated within 24 h to those treated after a longer surgical delay.</p><p><strong>Results: </strong>Among the 2320 patients enrolled, 1391 (60%) underwent surgery within 24 h, while 929 patients (40%) were treated after 24 h. For patients who underwent surgery within 24 h, the in-hospital mortality was 2.8%, and for those who underwent surgery after 24 h, it was 5.2% (p = 0.046; odds ratio (OR) 1.58). Age (p = 0.001; OR 1.06) and Nottingham score (p = 0.04; OR 1.32) are factors predicting mortality. Acute infections were related to a high risk of mortality (p = 0.001; OR 5.99), both in patients treated within and after 24 h. Acute events, such as atrial fibrillation and electrolyte imbalance, were related to mortality risk only in patients treated within 24 h (p = 0.001 versus p = 0.51). Neural network analysis revealed that atrial fibrillation (AF), flutter, and electrolyte imbalance had the highest relative weight for mortality in patients treated in the first 24 h; by contrast, renal failure and pneumonia were most present in patients who died that were treated after 24 h.</p><p><strong>Conclusions: </strong>Hip fracture is known to be a significant cause of morbidity and mortality in older adults. The impact of the timing of surgical treatment in those patients is crucial for postoperative outcomes. Early surgery is essential to reduce the risk of mortality. Our study has shown that, while in the case of acute and reversible conditions, waiting about 24 h to stabilize the patient with preoperative stabilization protocols, such as managing anticoagulation,
导读:老年人髋部骨折的死亡率很高,据报道,一年内的死亡率约为35%。如今,这些骨折的发生率正在上升,由于人口老龄化,这一趋势预计会进一步增加。由于存在多种合并症,这些患者的治疗时机和围手术期管理通常具有挑战性,这些合并症是术后死亡的重要危险因素。本研究旨在评估手术时机与住院死亡率之间的关系,分析急性事件和慢性既往合并症在患者预后中的作用。材料和方法:这是一项单中心、回顾性观察性研究(2018年1月至2023年6月)。所有连续≥65岁且诊断为股骨近端骨折的患者均被纳入研究。主要研究终点是评估与住院死亡率相关的危险因素。次要终点是评估手术时间和住院死亡率之间的关系,包括先前存在的合并症、Charlson合并症指数和诺丁汉髋部骨折评分等因素。预测死亡率的每个因素的相对权重也使用神经网络分析进行评估,比较24小时内治疗的患者和手术延迟较长时间后治疗的患者。结果:2320例入组患者中,24 h内手术1391例(60%),24 h后治疗929例(40%)。24 h内手术患者住院死亡率为2.8%,24 h后手术患者住院死亡率为5.2% (p = 0.046;优势比(OR) 1.58)。年龄(p = 0.001;OR 1.06)和Nottingham评分(p = 0.04;OR 1.32)是预测死亡率的因素。急性感染与高死亡率相关(p = 0.001;OR 5.99)。急性事件,如心房颤动和电解质失衡,仅在24小时内治疗的患者中与死亡风险相关(p = 0.001对p = 0.51)。神经网络分析显示,房颤(AF)、扑动和电解质失衡在治疗前24小时内对患者死亡率的相对权重最高;相比之下,肾衰竭和肺炎在24小时后死亡的患者中最常见。结论:髋部骨折是老年人发病率和死亡率的重要原因。手术治疗时机的影响对这些患者的术后结果至关重要。早期手术对于降低死亡风险至关重要。我们的研究表明,虽然在急性和可逆性疾病的情况下,等待约24小时来稳定患者的术前稳定方案,如抗凝管理,优化血流动力学,或解决急性医疗条件,包括感染预防,保证更好的结果,在败血症或急性感染存在的情况下,优化患者在手术前和术后的长时间等待无助于改善结果。
{"title":"Surgical timing and clinical factor predicting in-hospital mortality in older adults with hip fractures: a neuronal network analysis.","authors":"Raffaele Vitiello, Elisa Pesare, Giacomo Capece, Emidio Di Gialleonardo, Andrea De Matthaeis, Francesco Franceschi, Giulio Maccauro, Marcello Covino","doi":"10.1186/s10195-025-00846-x","DOIUrl":"10.1186/s10195-025-00846-x","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Hip fractures in older adults are associated with a significant mortality rate, which has been reported to be around 35% within a year. Today, the incidence of these fractures is on the rise, and this trend is expected to increase even more owing to the aging of the population. Treatment timing and perioperative management of these patients are typically challenging owing to the presence of multiple comorbidities that are important risk factors for mortality after surgery. This study aims to evaluate the relationship between surgical timing and in-hospital mortality, analyzing the role of both acute events and chronic preexisting comorbidities in patient outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;This is a single-center, retrospective observational study (from January 2018 until June 2023). All consecutive patients ≥ 65 years with a diagnosis of proximal femur fracture were enrolled. The primary study endpoint was to evaluate risk factors associated with in-hospital mortality. The secondary endpoint was the assessment of the relationship between surgical timing and in-hospital mortality, including factors such as preexisting comorbidities, the Charlson Comorbidity Index, and the Nottingham Hip Fracture Score. The relative weight of each factor for predicting the mortality rate was also evaluated using neural network analysis, comparing patients treated within 24 h to those treated after a longer surgical delay.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Among the 2320 patients enrolled, 1391 (60%) underwent surgery within 24 h, while 929 patients (40%) were treated after 24 h. For patients who underwent surgery within 24 h, the in-hospital mortality was 2.8%, and for those who underwent surgery after 24 h, it was 5.2% (p = 0.046; odds ratio (OR) 1.58). Age (p = 0.001; OR 1.06) and Nottingham score (p = 0.04; OR 1.32) are factors predicting mortality. Acute infections were related to a high risk of mortality (p = 0.001; OR 5.99), both in patients treated within and after 24 h. Acute events, such as atrial fibrillation and electrolyte imbalance, were related to mortality risk only in patients treated within 24 h (p = 0.001 versus p = 0.51). Neural network analysis revealed that atrial fibrillation (AF), flutter, and electrolyte imbalance had the highest relative weight for mortality in patients treated in the first 24 h; by contrast, renal failure and pneumonia were most present in patients who died that were treated after 24 h.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Hip fracture is known to be a significant cause of morbidity and mortality in older adults. The impact of the timing of surgical treatment in those patients is crucial for postoperative outcomes. Early surgery is essential to reduce the risk of mortality. Our study has shown that, while in the case of acute and reversible conditions, waiting about 24 h to stabilize the patient with preoperative stabilization protocols, such as managing anticoagulation, ","PeriodicalId":48603,"journal":{"name":"Journal of Orthopaedics and Traumatology","volume":"26 1","pages":"30"},"PeriodicalIF":3.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early versus standard return to play following ACL reconstruction: impact on volume of play and career longevity in 180 professional European soccer players: a retrospective cohort study. 前交叉韧带重建后的早期与标准恢复:对180名欧洲职业足球运动员比赛量和职业生涯寿命的影响:一项回顾性队列研究
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-05-12 DOI: 10.1186/s10195-025-00837-y
Michael Battaglia, Justin W Arner, Kaare S Midtgaard, Daniel B Haber, Liam A Peebles, Annalise M Peebles, Phob Ganokroj, Ryan J Whalen, Matthew T Provencher, Guglielmo Torre, Riccardo Ciatti, Pier Paolo Mariani

Background: Patients typically follow a 7-9-month return to play (RTP) protocol following anterior cruciate ligament reconstruction (ACLR); however, much of these data have been based on non-elite athletes. The purpose of this study is to understand whether professional soccer players returning to competition < 6-months following ACLR will have an increased risk of graft failure, play fewer seasons postoperatively, and have lower volume of play compared with those returning > 6 months.

Materials and methods: A total of 180 male professional European soccer players were enrolled and underwent ACLR with a single surgeon between April 2008 and December 2016 and returned to sport < 6 months (early RTP group, n = 92) or > 6 months (standard RTP group, n = 88). Time from intervention to RTP (days), same season returns, total games and average minutes played in return season, seasons played after surgery, and playing status were recorded.

Results: The early RTP group returned to soccer sooner (142.8 ± 21.4 days) than the standard RTP group (276.2 ± 118.9) (p < 0.01), and more players returned the same season as the injury in the early RTP group (n = 55/92, 62.5%) than the standard RTP group (n = 18/88, 20.5%) (p < 0.01). The difference in average minutes per game in the first season back was not statistically significant (early RTP, 56.7 ± 22.3 min; standard RTP 49.9 ± 29.8 min, p = 0.094). The early RTP group had significantly longer careers following ACLR (5.7 ± 2.2 seasons) than the standard RTP group (4.7 ± 2.4 seasons) (p = 0.005). The early RTP group sustained more reruptures (n = 4, 4.4%) than the standard RTP group (n = 1, 1.1%).

Conclusions: Professional European soccer players returning to competition < 6 months following ACLR did not have poorer outcomes than those who returned > 6 months despite the fact that there were three more failures. However, the early RTP group players were more likely to return during the same season, had longer careers after ACLR, and played a similar number of games and minutes per game, but had more graft failures.

Level of evidence: Retrospective cohort study level IV.

Trial registration: Retrospectively registered according to prot. Professionisti_OSS_22.

背景:患者通常在前交叉韧带重建(ACLR)后7-9个月恢复比赛(RTP)方案;然而,这些数据大多是基于非精英运动员。本研究的目的是了解职业足球运动员是否在6个月后重返赛场。材料与方法:在2008年4月至2016年12月期间,共招募了180名欧洲男性职业足球运动员,由一名外科医生进行了ACLR手术,并于6个月后恢复运动(标准RTP组,n = 88)。记录从干预到RTP的时间(天),同一赛季的回归,回归赛季的总场次和平均上场时间,手术后的出场时间,以及比赛状态。结果:早期RTP组比标准RTP组(276.2±118.9)早(142.8±21.4天)重返赛场。(p)结论:欧洲职业足球运动员尽管比标准RTP组多3次失败,但仍能在6个月后重返赛场。然而,早期的RTP组球员更有可能在同一赛季复出,在ACLR之后有更长的职业生涯,每场比赛的出场次数和上场时间相似,但有更多的移植失败。证据水平:回顾性队列研究iv级。试验注册:根据prot回顾性注册。Professionisti_OSS_22。
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引用次数: 0
Risk factors associated with delayed union after open reduction and plate fixation for humeral diaphyseal fractures. 肱骨骨干骨折切开复位钢板固定后延迟愈合的相关危险因素。
IF 3 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-05-12 DOI: 10.1186/s10195-025-00843-0
Yuh-Ruey Kuo, Po-Yen Ko, Chun-Yi Lee, Ting-Chien Tsai, Chang-Han Chuang, Shu-Hsin Yao, Po-Ting Wu

Background: The risk factors related to delayed union in humeral diaphyseal fractures (HDFs) following surgical osteosynthesis remain unclear. Therefore, this study aimed to evaluate radiological outcomes and the risk factors associated with delayed union in a retrospective cohort of patients who underwent open reduction and plate fixation (ORPF) for acute HDFs.

Materials and methods: Consecutive patients with AO/OTA 12-A and AO/OTA 12-B fractures who underwent ORPF using standard compression techniques between 2017 and 2020 were enrolled in the study. Demographic data, along with serial medical records and radiographs, were collected. The included patients were divided into two groups: the timely union (union occurring within 6 months postoperatively) and the delayed union group (union occurring between 6 and 12 months postoperatively). Differences between the groups were examined, and logistic regression was subsequently applied for risk factor analysis.

Results: Sixty-five cases were included in the study, consisting of 34 males and 31 females, with a median age of 38.9 years. Among these, 45 cases (69.2%) were classified in the timely union group, while 20 cases (30.8%) were classified in the delayed union group. Overall, 30 cases (46.2%) demonstrated secondary bony union. Significant differences were observed between groups in terms of fracture pattern, immediate postoperative fracture gap, union pattern, and complication rate (p < 0.05 for all comparisons). Multivariate logistic regression analysis revealed that the use of interfragmentary screw and the presence of postoperative complications were independent predictors of delayed union, with an adjusted odds ratio of 0.14 and 5.76, respectively.

Conclusions: In ORPF for acute HSFs, 30 out of 65 cases demonstrated secondary bone union despite the use of standard compression techniques. The application of interfragmentary screws significantly reduces the risk of delayed union. Conversely, the presence of postoperative complications is associated with an increased likelihood of delayed union.

Level of evidence: 3 Trial Registration All procedures were approved by the institutional review board of the authors' hospital (IRB nos. A-ER-112-395 and IRB20230089).

背景:肱骨骨干骨折(HDFs)术后延迟愈合的危险因素尚不清楚。因此,本研究旨在评估一组接受切开复位钢板固定(ORPF)治疗急性HDFs患者的放射学结果和延迟愈合相关的危险因素。材料和方法:2017年至2020年期间,采用标准压缩技术连续接受ORPF的AO/OTA 12-A和AO/OTA 12-B骨折患者纳入研究。收集了人口统计数据以及一系列医疗记录和x射线照片。纳入的患者分为及时愈合组(术后6个月内愈合)和延迟愈合组(术后6 ~ 12个月愈合)。检查各组之间的差异,随后应用逻辑回归进行危险因素分析。结果:纳入病例65例,男34例,女31例,中位年龄38.9岁。其中及时愈合组45例(69.2%),延迟愈合组20例(30.8%)。总体而言,30例(46.2%)表现为继发性骨愈合。在骨折类型、术后即刻骨折间隙、愈合模式和并发症发生率方面,组间观察到显著差异(p)。结论:在急性hsf的ORPF治疗中,尽管使用标准压迫技术,65例患者中有30例出现继发性骨愈合。骨折段间螺钉的应用可显著降低延迟愈合的风险。相反,术后并发症的出现与延迟愈合的可能性增加有关。所有程序均经作者所在医院机构审查委员会批准(IRB号:A-ER-112-395和IRB20230089)。
{"title":"Risk factors associated with delayed union after open reduction and plate fixation for humeral diaphyseal fractures.","authors":"Yuh-Ruey Kuo, Po-Yen Ko, Chun-Yi Lee, Ting-Chien Tsai, Chang-Han Chuang, Shu-Hsin Yao, Po-Ting Wu","doi":"10.1186/s10195-025-00843-0","DOIUrl":"10.1186/s10195-025-00843-0","url":null,"abstract":"<p><strong>Background: </strong>The risk factors related to delayed union in humeral diaphyseal fractures (HDFs) following surgical osteosynthesis remain unclear. Therefore, this study aimed to evaluate radiological outcomes and the risk factors associated with delayed union in a retrospective cohort of patients who underwent open reduction and plate fixation (ORPF) for acute HDFs.</p><p><strong>Materials and methods: </strong>Consecutive patients with AO/OTA 12-A and AO/OTA 12-B fractures who underwent ORPF using standard compression techniques between 2017 and 2020 were enrolled in the study. Demographic data, along with serial medical records and radiographs, were collected. The included patients were divided into two groups: the timely union (union occurring within 6 months postoperatively) and the delayed union group (union occurring between 6 and 12 months postoperatively). Differences between the groups were examined, and logistic regression was subsequently applied for risk factor analysis.</p><p><strong>Results: </strong>Sixty-five cases were included in the study, consisting of 34 males and 31 females, with a median age of 38.9 years. Among these, 45 cases (69.2%) were classified in the timely union group, while 20 cases (30.8%) were classified in the delayed union group. Overall, 30 cases (46.2%) demonstrated secondary bony union. Significant differences were observed between groups in terms of fracture pattern, immediate postoperative fracture gap, union pattern, and complication rate (p < 0.05 for all comparisons). Multivariate logistic regression analysis revealed that the use of interfragmentary screw and the presence of postoperative complications were independent predictors of delayed union, with an adjusted odds ratio of 0.14 and 5.76, respectively.</p><p><strong>Conclusions: </strong>In ORPF for acute HSFs, 30 out of 65 cases demonstrated secondary bone union despite the use of standard compression techniques. The application of interfragmentary screws significantly reduces the risk of delayed union. Conversely, the presence of postoperative complications is associated with an increased likelihood of delayed union.</p><p><strong>Level of evidence: </strong>3 Trial Registration All procedures were approved by the institutional review board of the authors' hospital (IRB nos. A-ER-112-395 and IRB20230089).</p>","PeriodicalId":48603,"journal":{"name":"Journal of Orthopaedics and Traumatology","volume":"26 1","pages":"28"},"PeriodicalIF":3.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Journal of Orthopaedics and Traumatology
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