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"Vaccine hesitancy and acceptance in Latvia and Lithuania after the COVID-19 pandemic " “COVID-19大流行后拉脱维亚和立陶宛对疫苗的犹豫和接受”
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-12-06 DOI: 10.1016/j.hlpt.2025.101146
Liubove Murauskiene , Daiga Behmane , Ausra Berzanskyte

Objectives

This study investigates vaccine hesitancy and acceptance in Latvia and Lithuania following the COVID-19 pandemic, contextualising current attitudes within historical and institutional frameworks, quantifying public preferences for vaccine features and policy measures, and identifying predictors of vaccine acceptance to inform future public health strategies.

Methods

A cross-sectional survey using the VaxPref database was conducted with demographically balanced samples from Latvia (n = 1109) and Lithuania (n = 1010). A discrete choice experiment elicited preferences for vaccine characteristics and public health policies. Latent class analysis explored heterogeneity in vaccine acceptance, incorporating sociodemographic and attitudinal predictors such as trust in public health authorities and prior vaccination behaviour.

Results

Three classes emerged: Provaxers, Refusers, and Hesitants. Nearly half of respondents in both countries were Refusers, a marked increase from earlier surveys.Refusers were indifferent to vaccine attributes and strongly averse to vaccination, while Provaxers and Hesitants preferred higher vaccine effectiveness and Westernmanufactured vaccines. Trust public health authorities and prior COVID-19 vaccination were the strongest predictors of acceptance. Policy-related variables, such as social restrictions and mandates, had statistically significant but minor associations, with both countries preferring the absence of constraints. Gender and religious affiliation influenced hesitancy in a country-specific manner.

Conclusions

Vaccine attitudes in Latvia and Lithuania are shaped more by trust public health authorities and prior behaviours than by traditional sociodemographic factors. The high proportion of systematic Refusers poses a significant challenge for pandemic preparedness, highlighting the need for targeted trust-building initiatives and contextspecific policies to improve vaccine uptake.

Public interest summary

Our study looked at why many people in Latvia and Lithuania are hesitant or refuse to get vaccinated, even after the COVID-19 pandemic. We found that nearly half of adults in both countries are strongly against vaccines, and this reluctance is not driven by age, education, or income. Instead, the main reasons are a lack of trust in public health authorities and past experiences with vaccination. While some people prefer vaccines that are more effective or made in Western countries, regulations such as societal limitations or mandates little affected their choices. To increase vaccine uptake in the future, context-specific approaches and trust-building are essential.
本研究调查了COVID-19大流行后拉脱维亚和立陶宛的疫苗犹豫和接受情况,在历史和制度框架下分析当前的态度,量化公众对疫苗特征和政策措施的偏好,并确定疫苗接受的预测因素,为未来的公共卫生战略提供信息。方法采用VaxPref数据库对来自拉脱维亚(n = 1109)和立陶宛(n = 1010)的人口统计学平衡样本进行横断面调查。一个离散选择实验引出了对疫苗特性和公共卫生政策的偏好。潜在类别分析探讨了疫苗接受的异质性,结合社会人口统计学和态度预测因素,如对公共卫生当局的信任和先前的疫苗接种行为。结果出现了三种类型:鼓动者、拒绝者和犹豫者。两国近一半的受访者都是“拒绝者”,与之前的调查相比有显著增加。拒绝者对疫苗属性漠不关心,强烈反对接种疫苗,而支持者和犹豫者更喜欢更高的疫苗有效性和西方制造的疫苗。信任公共卫生当局和之前的COVID-19疫苗接种是接受度的最强预测因素。与政策有关的变量,如社会限制和授权,在统计上有显著但较小的关联,两国都倾向于没有限制。性别和宗教信仰以不同国家的具体方式影响犹豫不决。结论拉脱维亚和立陶宛的疫苗态度更多地受信任的公共卫生当局和既往行为的影响,而不是传统的社会人口因素。系统性拒绝者的高比例对大流行的防范构成了重大挑战,突出表明需要有针对性的建立信任倡议和针对具体情况的政策来改善疫苗的吸收。您的研究调查了为什么拉脱维亚和立陶宛的许多人犹豫不决或拒绝接种疫苗,即使在COVID-19大流行之后也是如此。我们发现,这两个国家近一半的成年人强烈反对接种疫苗,这种不情愿与年龄、教育或收入无关。相反,主要原因是对公共卫生当局缺乏信任以及过去的疫苗接种经验。虽然有些人更喜欢更有效的疫苗或西方国家生产的疫苗,但社会限制或强制等法规对他们的选择几乎没有影响。为了在未来增加疫苗的吸收,针对具体情况的方法和建立信任至关重要。
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引用次数: 0
Perceptions, attitudes, and intention to adopt artificial intelligence in healthcare among medical and pharmacy students 医学和药学专业学生在医疗保健中采用人工智能的认知、态度和意图
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-12-04 DOI: 10.1016/j.hlpt.2025.101145
Luu Thi Thuy , Hoang Thi Ngoc Sen , Nguyen Huong Giang , Huynh Huu Bon , Vo Thi Ngoc Ha

Objectives

This study aimed to describe medical and pharmacy students' perceptions, attitudes, and intention to adopt artificial intelligence (AI) in healthcare and identify factors influencing their intention to use AI.

Methods

This cross-sectional study was conducted in Vietnam in December 2024 using a convenience sampling strategy. A self-administered questionnaire was employed to evaluate students’ perceptions of AI applications, attitudes toward AI, and their intention to integrate AI into healthcare. Hierarchical regression analysis was carried out to identify significant factors influencing intention.

Results

Most participants acknowledged AI’s advantages, with 66.9 % recognizing its role in patient documentation, 63.5 % agreeing it supports preventative health recommendations, and 61.9 % endorsing its contribution to capacity planning. However, skepticism remained, as 28.1 % doubted AI’s effectiveness in psychiatric counseling, 25.7 % questioned its application in surgery, and 22.0 % were uncertain about its ability to analyze patient data for prognoses. Attitudinally, 63.1 % expressed concern over AI’s impact on job security, though 47.2 % maintained a generally positive outlook on AI’s role in healthcare. Over half of the respondents expressed a strong willingness to integrate AI into their future practice, with 60.1 % affirming their intent to use AI-based technology. Hierarchical regression analysis highlighted attitudes toward AI (ß = 0.528), perceptions of AI in individual patient care (ß = 0.207), and self-assessed technology skills (ß = -0.121) as significant predictors of intention.

Conclusions

Attitudes, perceptions of AI in individual patient care, and technology skills strongly influenced students’ intention to adopt AI. Integrating AI education into medical curricula may improve preparedness for AI-driven healthcare.
目的本研究旨在描述医学和药学专业学生在医疗保健中采用人工智能(AI)的认知、态度和意向,并确定影响其使用AI意向的因素。方法本横断面研究于2024年12月在越南进行,采用方便抽样策略。采用一份自我管理的问卷来评估学生对人工智能应用的看法、对人工智能的态度以及他们将人工智能融入医疗保健的意图。进行层次回归分析,找出影响意向的显著因素。结果大多数参与者承认人工智能的优势,66.9%的人认识到人工智能在患者记录中的作用,63.5%的人同意人工智能支持预防性健康建议,61.9%的人赞同人工智能对能力规划的贡献。然而,怀疑仍然存在,28.1%的人怀疑人工智能在精神咨询方面的有效性,25.7%的人质疑其在外科手术中的应用,22.0%的人不确定其分析患者数据以预测预后的能力。从态度上看,63.1%的人担心人工智能对就业保障的影响,尽管47.2%的人对人工智能在医疗保健领域的作用持普遍积极的看法。超过一半的受访者表达了将人工智能融入未来实践的强烈意愿,60.1%的受访者肯定他们打算使用基于人工智能的技术。分层回归分析强调,对人工智能的态度(ß = 0.528)、对人工智能在个体患者护理中的感知(ß = 0.207)和自我评估的技术技能(ß = -0.121)是意向的重要预测因素。结论对人工智能在个体病人护理中的态度、认知和技术技能对学生采用人工智能的意愿有很大影响。将人工智能教育纳入医学课程,可以改善人工智能驱动的医疗保健的准备工作。
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引用次数: 0
A systematic review on the impact of healthcare consolidation in the digital era 对数字时代医疗保健整合影响的系统回顾
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-29 DOI: 10.1016/j.hlpt.2025.101138
Min Chen , Arman Ghafoori , Wenbin Zhang
<div><h3>Objectives</h3><div>This systematic review examines how healthcare provider consolidation, particularly among hospitals and health systems, affects Health Information Technology (HIT), with a focus on Electronic Health Records (EHRs) and interoperability.</div></div><div><h3>Methods</h3><div>Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, we reviewed literature published through June 2023 using major databases such as PubMed and Cochrane. Data from 16 peer-reviewed studies covering 125 quantitative analyses were synthesized to analyze how provider consolidation shapes HIT infrastructure and performance, including information exchange, EHR vendor diversity, and downstream outcomes such as healthcare access, cost efficiency, and care quality.</div></div><div><h3>Results</h3><div>The findings show that consolidation is significantly associated with improvements in information exchange and increased healthcare utilization, particularly in emergency department and primary care settings. While the improvements are encouraging, they are often incremental and do not yet reflect full interoperability, which involves not only data sharing but also the seamless, meaningful use of information across systems. Evidence on cost-effectiveness, care quality, and patient outcomes is mixed.</div></div><div><h3>Conclusions</h3><div>Consolidation may improve certain aspects of digital infrastructure, especially data exchange, but does not guarantee full interoperability or better downstream outcomes. These findings point to the need for future research to go beyond measuring data exchange by assessing actual interoperability performance and examining the real-world challenges of HIT integration in consolidated systems. As healthcare consolidation continues, careful evaluation of its digital, clinical, and organizational impacts will help advance interoperability and support equitable, high-quality care.</div></div><div><h3>Public Interest Summary</h3><div>This review explores how hospital and health system consolidations affect Health Information Technology (HIT), particularly Electronic Health Records (EHRs) and interoperability. Through a systematic search, we identified 16 papers and 125 quantitative analyses. The findings show that consolidation is significantly associated with improved information exchange and increased healthcare use. While the improvements are encouraging, they are often partial and do not mean that systems can fully and effectively use shared data across all settings. The impact on cost-effectiveness, care quality, and patient outcomes varies across studies. Our review highlights the need for more research that looks beyond basic data sharing to evaluate how well health systems actually use information and to understand the practical challenges of integrating technology after hospitals or health systems merge. The findings also offer insights to inform policy efforts aimed at promotin
本系统综述研究了医疗保健提供者整合,特别是医院和卫生系统之间的整合,如何影响卫生信息技术(HIT),重点是电子健康记录(EHRs)和互操作性。方法:遵循PRISMA(首选系统评价和荟萃分析报告项目)指南,我们使用PubMed和Cochrane等主要数据库回顾了截至2023年6月发表的文献。来自16个同行评议研究的数据,涵盖125个定量分析,用于分析供应商整合如何影响HIT基础设施和性能,包括信息交换、EHR供应商多样性和下游结果,如医疗保健访问、成本效率和护理质量。结果研究结果表明,合并与信息交流的改善和医疗保健利用率的提高显著相关,特别是在急诊科和初级保健机构。虽然这些改进令人鼓舞,但它们往往是渐进式的,尚未反映出完全的互操作性,这不仅涉及数据共享,还涉及跨系统的无缝、有意义的信息使用。关于成本效益、护理质量和患者预后的证据参差不齐。整合可以改善数字基础设施的某些方面,特别是数据交换,但不能保证完全的互操作性或更好的下游结果。这些发现表明,未来的研究需要通过评估实际的互操作性性能和检查整合系统中HIT集成的现实挑战来超越测量数据交换的范围。随着医疗保健整合的继续,仔细评估其数字、临床和组织影响将有助于提高互操作性,并支持公平、高质量的医疗服务。本综述探讨了医院和卫生系统合并如何影响卫生信息技术(HIT),特别是电子健康记录(EHRs)和互操作性。通过系统检索,我们确定了16篇论文和125个定量分析。研究结果表明,整合与改进的信息交换和增加的医疗保健使用显著相关。虽然这些改进令人鼓舞,但它们往往是局部的,并不意味着系统可以在所有设置中充分有效地使用共享数据。对成本效益、护理质量和患者预后的影响因研究而异。我们的综述强调,需要开展更多的研究,超越基本的数据共享,评估卫生系统实际使用信息的情况,并了解医院或卫生系统合并后整合技术的实际挑战。研究结果还为在日益数字化一体化的医疗环境中促进公平、高质量医疗的政策努力提供了见解。
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引用次数: 0
Does a tiered diagnosis and treatment system enhance self-rated health outcomes among middle-aged and older patients with hypertension or diabetes? Evidence from China 分级诊疗系统是否能提高中老年高血压或糖尿病患者的自评健康结果?来自中国的证据
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-22 DOI: 10.1016/j.hlpt.2025.101137
Wen He

Objective

Addressing healthcare challenges in aging societies represents a pressing global priority for countries worldwide. To increase healthcare accessibility and equity, China introduced its tiered diagnosis and treatment (TDT) system in 2015. This study examines the impacts of this policy change on self-rated health outcomes among middle-aged and older patients with hypertension or diabetes.

Methods

Under a quasi-experimental framework, this study leveraged longitudinal data from four waves (2011–2018) of the China Health and Retirement Longitudinal Study (CHARLS) and employed a difference-in-differences (DID) approach to identify the impacts. To supplement this analysis, a moderating effects model was implemented to explore the potential moderating influence of health insurance coverage, primary care utilization, and treatment compliance.

Results

The findings revealed that following the implementation of TDT, middle-aged and older patients with hypertension or diabetes experienced a marked 31.03% enhancement in self-rated health outcomes (P < 0.05), with effects intensifying progressively over time. Additionally, moderating analysis demonstrated that patients' health insurance coverage (P < 0.01), expanded insurance benefits (P < 0.05), heightened primary care utilization (P < 0.1), and enhanced treatment compliance (P < 0.01) collectively amplified the positive health impacts.

Conclusions

This study offers compelling new causal evidence that strengthening primary care systems and strategically refining healthcare resource allocation have provided tangible health benefits to vulnerable populations. Notably, as China's TDT operates on a voluntary basis, its experience provides valuable insights for countries grappling with escalating medical demands alongside fragmented healthcare systems.

Public Interest Summary

This study explored the impacts of the tiered diagnosis and treatment reform in China on self-rated health outcomes among middle-aged and older patients with hypertension or diabetes. By leveraging longitudinal data from a national survey and conducting a DID analysis, it provides novel evidence that the policy reform significantly enhanced the health status of this vulnerable population, with health insurance coverage and benefits, primary care utilization, and treatment compliance acting as pivotal factors in amplifying these health benefits.
应对老龄化社会中的医疗挑战是世界各国迫切的全球优先事项。为了提高医疗服务的可及性和公平性,中国于2015年推出了分级诊疗(TDT)制度。本研究考察了这一政策变化对中老年高血压或糖尿病患者自评健康结果的影响。方法在准实验框架下,本研究利用中国健康与退休纵向研究(CHARLS)四波(2011-2018)的纵向数据,并采用差分法(DID)来确定影响。为了补充这一分析,我们实施了一个调节效应模型来探索健康保险覆盖率、初级保健利用和治疗依从性的潜在调节作用。结果实施TDT后,中老年高血压或糖尿病患者的自评健康结果显著提高31.03% (P < 0.05),且随时间的推移,效果逐渐增强。此外,调节分析表明,患者健康保险覆盖率(P < 0.01)、扩大保险福利(P < 0.05)、提高初级保健利用率(P < 0.1)和提高治疗依从性(P < 0.01)共同放大了健康的积极影响。结论本研究提供了令人信服的新的因果证据,表明加强初级保健系统和战略性地优化医疗资源分配为弱势群体提供了切实的健康效益。值得注意的是,由于中国的TDT是在自愿的基础上运作的,它的经验为那些正在努力应对不断上升的医疗需求和分散的医疗体系的国家提供了宝贵的见解。摘要本研究探讨中国分级诊疗改革对中老年高血压或糖尿病患者自评健康结局的影响。通过利用一项全国调查的纵向数据并进行DID分析,该研究提供了新的证据,表明政策改革显著改善了这一弱势群体的健康状况,医疗保险覆盖范围和福利、初级保健利用和治疗依从性是放大这些健康效益的关键因素。
{"title":"Does a tiered diagnosis and treatment system enhance self-rated health outcomes among middle-aged and older patients with hypertension or diabetes? Evidence from China","authors":"Wen He","doi":"10.1016/j.hlpt.2025.101137","DOIUrl":"10.1016/j.hlpt.2025.101137","url":null,"abstract":"<div><h3>Objective</h3><div>Addressing healthcare challenges in aging societies represents a pressing global priority for countries worldwide. To increase healthcare accessibility and equity, China introduced its tiered diagnosis and treatment (TDT) system in 2015. This study examines the impacts of this policy change on self-rated health outcomes among middle-aged and older patients with hypertension or diabetes.</div></div><div><h3>Methods</h3><div>Under a quasi-experimental framework, this study leveraged longitudinal data from four waves (2011–2018) of the China Health and Retirement Longitudinal Study (CHARLS) and employed a difference-in-differences (DID) approach to identify the impacts. To supplement this analysis, a moderating effects model was implemented to explore the potential moderating influence of health insurance coverage, primary care utilization, and treatment compliance.</div></div><div><h3>Results</h3><div>The findings revealed that following the implementation of TDT, middle-aged and older patients with hypertension or diabetes experienced a marked 31.03% enhancement in self-rated health outcomes (<em>P</em> &lt; 0.05), with effects intensifying progressively over time. Additionally, moderating analysis demonstrated that patients' health insurance coverage (<em>P</em> &lt; 0.01), expanded insurance benefits (<em>P</em> &lt; 0.05), heightened primary care utilization (<em>P</em> &lt; 0.1), and enhanced treatment compliance (<em>P</em> &lt; 0.01) collectively amplified the positive health impacts.</div></div><div><h3>Conclusions</h3><div>This study offers compelling new causal evidence that strengthening primary care systems and strategically refining healthcare resource allocation have provided tangible health benefits to vulnerable populations. Notably, as China's TDT operates on a voluntary basis, its experience provides valuable insights for countries grappling with escalating medical demands alongside fragmented healthcare systems.</div></div><div><h3>Public Interest Summary</h3><div>This study explored the impacts of the tiered diagnosis and treatment reform in China on self-rated health outcomes among middle-aged and older patients with hypertension or diabetes. By leveraging longitudinal data from a national survey and conducting a DID analysis, it provides novel evidence that the policy reform significantly enhanced the health status of this vulnerable population, with health insurance coverage and benefits, primary care utilization, and treatment compliance acting as pivotal factors in amplifying these health benefits.</div></div>","PeriodicalId":48672,"journal":{"name":"Health Policy and Technology","volume":"15 1","pages":"Article 101137"},"PeriodicalIF":3.7,"publicationDate":"2025-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145684798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"...it saves so much time": A qualitative exploration of the use of Generative Artificial Intelligence by the health workforce “…它节省了大量时间”:对卫生工作人员使用生成式人工智能的定性探索
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-22 DOI: 10.1016/j.hlpt.2025.101136
Mia Nazir , Jane Ellen Carland , Melanie Keep , Anna Janssen

Objectives

Generative Artificial Intelligence (Gen AI) has become an increasingly prevalent conversation in healthcare over the past few years. Though there have been research projects and articles exploring the administrative and clinical uses of such technologies, there has been little exploration of health professional perspectives, hopes and concerns. This study sought to explore perspectives and examine the barriers and enablers of Gen AI in healthcare.

Methodology

Australian health professionals participated in a mixed-methods study. A survey (n=31) explored the Six Dimensions of Healthcare Quality Framework, capturing quantitative (Likert-scale responses) and qualitative (free-text) data. Semi-structured interviews (n=10) explored participant perceptions of Gen AI. Quantitative data was analysed using descriptive statistics. Qualitative data was thematically analysed.

Results

Most survey respondents (74.14 %) reported having used Gen AI to support their work, but only a few (25.81 %) reported organisational supports for use of these technologies. Analysis of the qualitative data aligned with the survey responses. Five themes were generated through thematic analysis, aligning with health professional’s perceived use of Gen AI chatbots, benefits, risks, as well as drivers of safe use and opportunities for the future.

Conclusion

Health professionals see potential for using Gen AI to support their work, with enthusiasm about the potential of Gen AI to reduce workloads, particularly in offloading administrative tasks. There is also awareness that Gen AI chatbots pose risks both at the individual level such as limited capability in using these technologies and at the organisational level such as lack of training to support in upskilling, and systemic concerns around policy gaps.

Public Interest Summary

Generative Artificial Intelligence (Gen AI) is increasingly topical in all aspects of life, and the health sector is no exception. Though there have been research projects focusing on Gen AI in healthcare, there has been little exploration of health professional views and concerns. This study spoke to health professionals and found that though there is a lot of interest in potential applications of Gen AI in healthcare, particularly in administrative offloading and clinical support, however, the benefits don’t yet outweigh the risks. Software developers must work alongside health professionals in developing a substantially beneficial program to support the safe use of Gen AI in healthcare as well as be well supported on an organisational level. There are also opportunities to develop education to build health professionals capacity to use GenAI safely and effectively, and for health service organisations to develop guidance and policies to clearly articulate what safe use looks like.
在过去的几年里,生成人工智能(Gen AI)已经成为医疗保健领域越来越普遍的话题。虽然有一些研究项目和文章探讨了这些技术的行政和临床应用,但对卫生专业的观点、希望和关切的探索却很少。本研究旨在探索新一代人工智能在医疗保健领域的障碍和推动因素。澳大利亚卫生专业人员参加了一项混合方法研究。一项调查(n=31)探讨了医疗保健质量框架的六个维度,捕获了定量(李克特量表反应)和定性(自由文本)数据。半结构化访谈(n=10)探讨了参与者对Gen AI的看法。定量资料采用描述性统计进行分析。对定性数据进行专题分析。大多数受访者(74.14%)表示使用了新一代人工智能来支持他们的工作,但只有少数受访者(25.81%)表示组织支持使用这些技术。定性数据的分析与调查结果一致。通过专题分析,产生了五个主题,与卫生专业人员对新一代人工智能聊天机器人的使用、好处、风险、安全使用的驱动因素和未来的机会相一致。卫生专业人员看到了使用新一代人工智能支持其工作的潜力,并对新一代人工智能减少工作量的潜力充满热情,特别是在减轻管理任务方面。人们还意识到,新一代人工智能聊天机器人在个人层面(如使用这些技术的能力有限)和组织层面(如缺乏支持技能提升的培训)都存在风险,以及对政策差距的系统性担忧。生成式人工智能(Gen AI)越来越多地应用于生活的各个方面,卫生部门也不例外。虽然有一些研究项目专注于医疗保健领域的人工智能,但对健康专业人士的观点和担忧的探索却很少。这项研究与卫生专业人员进行了交谈,发现尽管人们对人工智能在医疗保健领域的潜在应用很感兴趣,特别是在行政卸载和临床支持方面,但是,好处还没有超过风险。软件开发人员必须与卫生专业人员一起开发一个实质上有益的程序,以支持在医疗保健中安全使用人工智能,并在组织层面上得到良好的支持。也有机会发展教育,以建立卫生专业人员安全有效地使用GenAI的能力,并为卫生服务组织制定指导和政策,以清楚地阐明什么是安全使用。
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引用次数: 0
Biosimilar medicines in Malaysia: Unveiling new guidance for practice 马来西亚的生物仿制药:公布新的实践指南
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-21 DOI: 10.1016/j.hlpt.2025.101135
N Saad, Coleen SB Choo, H Chandriah, N Ahmad

Background

Biologics have transformed the treatment of chronic diseases, but their high-cost limits access and burdens healthcare budgets. Biosimilars, highly similar versions of approved biologics, offer a more affordable alternative. However, their complex nature necessitates distinct regulatory and clinical guidance to ensure their safe and effective use in the healthcare facilities.

Objective

This article highlights the policy initiatives undertaken by the Ministry of Health (MOH) Malaysia to develop a Position Statement, aimed at guiding the integration of biosimilars into Malaysia’s public healthcare system.

Method

A multi-stage process began in 2019 and involved structured stakeholder engagement, literature reviews, and consensus-building across medical and regulatory disciplines. Key areas addressed included interchangeability, switching, automatic substitution, prescribing, procurement, and pharmacovigilance. Two rounds of review were conducted, and stakeholder consensus was obtained through a binary survey, with a 70 % agreement threshold.

Results

Stakeholders from multiple specialties emphasized cautious but positive attitudes toward biosimilar use, especially for treatment-naïve or short-term therapy patients. The final guidance includes ten statements across five domains, emphasizing physician-led switching, prohibition of automatic substitution, indication-specific prescribing, and the need for robust pharmacovigilance. A total of 83 % of stakeholders supported the content, and 88 % endorsed its dissemination. The document was officially endorsed by the MOH Medicines Formulary Panel for implementation across all MOH facilities.

Conclusion

The position statements represent a critical step toward structured biosimilar adoption in Malaysia’s public healthcare. Ongoing implementation, education, and post-market evaluation will be essential to strengthen prescriber confidence, improve pharmacovigilance, and enhance patient trust in biosimilars.
生物制剂已经改变了慢性病的治疗方式,但其高昂的成本限制了获取,并增加了医疗预算负担。生物仿制药是与已获批准的生物制剂高度相似的版本,提供了一种更实惠的替代方案。然而,它们的复杂性需要独特的监管和临床指导,以确保它们在医疗机构中安全有效地使用。本文重点介绍了马来西亚卫生部(MOH)为制定立场声明而采取的政策举措,旨在指导将生物仿制药纳入马来西亚的公共医疗保健系统。方法一个多阶段的过程始于2019年,涉及结构化的利益相关者参与、文献综述以及跨医学和监管学科的共识建立。解决的关键领域包括互换性、切换、自动替代、处方、采购和药物警戒。进行了两轮审查,并通过二元调查获得利益相关者共识,同意阈值为70%。结果来自多个专业的利益相关者强调了对生物类似药使用的谨慎但积极的态度,特别是对于treatment-naïve或短期治疗患者。最终指南包括五个领域的十项声明,强调医生主导的转换、禁止自动替代、针对特定适应症的处方以及加强药物警戒的必要性。共有83%的利益相关者支持该内容,88%的人赞同其传播。该文件已得到卫生部药物处方小组的正式批准,以便在卫生部所有设施中实施。结论:该立场声明代表了马来西亚公共医疗保健采用结构化生物仿制药的关键一步。持续的实施、教育和上市后评价对于加强处方者信心、提高药物警戒性和增强患者对生物仿制药的信任至关重要。
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引用次数: 0
Impact of assistive technologies on caregiver burden and perseverance for people with dementia at home 辅助技术对在家照顾痴呆症患者的负担和毅力的影响
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-19 DOI: 10.1016/j.hlpt.2025.101134
G. Bagnasco , J. van Exel

Objectives

This study examines the relationship between the use of assistive technologies and the burden and perseverance time of informal caregivers of community-dwelling people with dementia.

Methods

An online survey of 342 informal caregivers in the Netherlands assessed objective burden (tasks and time involved in caregiving), subjective burden (personal experience of stress and strain), current perseverance time (time expected to be able to continue providing care), and well-being (overall happiness). Data included demographics, housing, neighbourhood characteristics, assistive technology use, and preferences for additional technologies. Multiple logistic regressions examined associations between assistive technology categories and caregiver outcomes (i.e., below-median weekly caregiving hours, Self-Rated Burden score; above-median CarerQol-7D score, CarerQol-VAS score, and Current Perseverance Time in months). Furthermore, multiple logistic regressions estimated the impact of the most desired technology category on the likelihood of extending the perseverance time by more than six months. Analyses were stratified by caregiver living arrangement (co-residing vs living nearby).

Results

Among co-residing caregivers, daily living support technologies were associated with reduced caregiving hours, whereas risk prevention technologies were linked to longer current perseverance time but also higher self-rated burden. Risk response technologies were also associated with higher self-rated burden. Among caregivers living nearby, risk prevention technologies were associated with higher quality of life. Moreover, daily living support and risk response technologies most strongly extended perseverance time beyond six months in both groups.

Conclusions

Assistive technologies play a nuanced role in supporting informal caregivers of community-dwelling people with dementia, with impacts differing by living arrangement and technology type.
目的探讨辅助技术的使用与社区痴呆患者非正式照护者负担和坚持时间的关系。方法对荷兰342名非正式护理人员进行在线调查,评估客观负担(护理任务和时间)、主观负担(个人压力和紧张经历)、当前坚持时间(预计能够继续提供护理的时间)和幸福感(总体幸福感)。数据包括人口统计、住房、社区特征、辅助技术使用和对其他技术的偏好。多重逻辑回归检验了辅助技术类别与护理人员结果(即每周护理时间低于中位数、自评负担评分、高于中位数的CarerQol-7D评分、CarerQol-VAS评分和当前坚持时间(以月为单位)之间的关系。此外,多重逻辑回归估计了最期望的技术类别对延长坚持时间超过六个月的可能性的影响。根据照顾者生活安排(共同居住vs住在附近)对分析进行分层。结果在共同居住的照顾者中,日常生活支持技术与减少照顾时间有关,而风险预防技术与更长的当前坚持时间有关,但也与更高的自评负担有关。风险应对技术也与较高的自评负担相关。在住在附近的护理人员中,风险预防技术与更高的生活质量相关。此外,日常生活支持和风险应对技术最有力地延长了两组的坚持时间超过6个月。结论辅助技术在支持社区痴呆患者非正式照护者方面发挥着微妙的作用,其影响因居住安排和技术类型而异。
{"title":"Impact of assistive technologies on caregiver burden and perseverance for people with dementia at home","authors":"G. Bagnasco ,&nbsp;J. van Exel","doi":"10.1016/j.hlpt.2025.101134","DOIUrl":"10.1016/j.hlpt.2025.101134","url":null,"abstract":"<div><h3>Objectives</h3><div>This study examines the relationship between the use of assistive technologies and the burden and perseverance time of informal caregivers of community-dwelling people with dementia.</div></div><div><h3>Methods</h3><div>An online survey of 342 informal caregivers in the Netherlands assessed objective burden (tasks and time involved in caregiving), subjective burden (personal experience of stress and strain), current perseverance time (time expected to be able to continue providing care), and well-being (overall happiness). Data included demographics, housing, neighbourhood characteristics, assistive technology use, and preferences for additional technologies. Multiple logistic regressions examined associations between assistive technology categories and caregiver outcomes (i.e., below-median weekly caregiving hours, Self-Rated Burden score; above-median CarerQol-7D score, CarerQol-VAS score, and Current Perseverance Time in months). Furthermore, multiple logistic regressions estimated the impact of the most desired technology category on the likelihood of extending the perseverance time by more than six months. Analyses were stratified by caregiver living arrangement (co-residing vs living nearby).</div></div><div><h3>Results</h3><div>Among co-residing caregivers, daily living support technologies were associated with reduced caregiving hours, whereas risk prevention technologies were linked to longer current perseverance time but also higher self-rated burden. Risk response technologies were also associated with higher self-rated burden. Among caregivers living nearby, risk prevention technologies were associated with higher quality of life. Moreover, daily living support and risk response technologies most strongly extended perseverance time beyond six months in both groups.</div></div><div><h3>Conclusions</h3><div>Assistive technologies play a nuanced role in supporting informal caregivers of community-dwelling people with dementia, with impacts differing by living arrangement and technology type.</div></div>","PeriodicalId":48672,"journal":{"name":"Health Policy and Technology","volume":"15 1","pages":"Article 101134"},"PeriodicalIF":3.7,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value-centred commissioning in primary health care: reform lessons from the Portuguese experience 初级卫生保健中以价值为中心的委托:来自葡萄牙经验的改革教训
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-14 DOI: 10.1016/j.hlpt.2025.101133
Paulo Santos , Isabel Nazaré , Luísa Sá

Background

Portuguese Primary Health Care commissioning has transitioned from centrally managed agreements to performance-based models. Despite this evolution, persistent structural and procedural inefficiencies limit its capacity to generate value. Comparative European experiences highlight alternative frameworks that emphasise outcome relevance, decentralisation, and system learning.

Objective

To propose a conceptual model for primary health care commissioning aligned with structure–process–outcome logic.

Methods

We conducted a narrative review to trace the evolution of commissioning in Portuguese Primary Health Care, focusing on its regulatory, financial, and performance roles. We used several sources, including legislation, policy documents, national and European reports, and academic literature. Analysis followed a structure–process–outcome framework. Comparative insights highlighted governance models, incentive structures, and reform opportunities aligned with value-based care and European benchmarks.

Results

Portuguese commissioning systems lack clinically meaningful outcome indicators and remain rigid in design. The new model offers a framework for aligning commissioning processes with population health needs, clinical relevance, and system adaptability. Comparative analysis shows that decentralised, context-sensitive models from other European countries are applicable and promising.

Conclusions

Commissioning reforms should centre around auditable, evidence-based outcome indicators tailored to local contexts. These indicators can enhance motivation, accountability, and continuous learning. Reforms are achievable within current organisational structures and planning cycles. Policymakers should consider decentralisation and a value-oriented approach to improve Primary Health Care delivery and responsiveness, particularly in systems facing similar structural constraints.
葡萄牙初级卫生保健委托已从中央管理的协议过渡到基于绩效的模式。尽管有这种发展,但持续的结构和程序上的低效限制了其创造价值的能力。比较欧洲的经验突出了强调结果相关性、权力下放和系统学习的替代框架。目的提出符合结构-过程-结果逻辑的初级卫生保健委托概念模型。方法我们进行了一项叙述性回顾,以追踪葡萄牙初级卫生保健委托的演变,重点关注其监管、财务和绩效角色。我们使用了几个来源,包括立法、政策文件、国家和欧洲报告以及学术文献。分析遵循结构-过程-结果框架。比较见解强调了与基于价值的护理和欧洲基准相一致的治理模式、激励结构和改革机会。结果葡萄牙的调试系统缺乏临床意义的结果指标,设计仍然僵化。新模式提供了一个框架,使调试过程与人口健康需求、临床相关性和系统适应性保持一致。对比分析表明,来自其他欧洲国家的分散的、上下文敏感的模式是适用的和有前途的。委托改革应围绕可审计的、基于证据的、适合当地情况的结果指标展开。这些指标可以增强动机、责任和持续学习。在目前的组织结构和规划周期内,改革是可以实现的。决策者应考虑权力下放和以价值为导向的方法,以改善初级卫生保健的提供和响应能力,特别是在面临类似结构限制的系统中。
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引用次数: 0
Four years upscaling telemonitoring to future-proof health care delivery in Dutch university hospitals: Before and after - where do we stand and what are the results? 四年来,荷兰大学医院将远程监控升级为面向未来的医疗服务:前后——我们的立场是什么,结果是什么?
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-13 DOI: 10.1016/j.hlpt.2025.101132
HJ Harm Gijsbers , S Azam Nurmohamed , Linda W Dusseljee–Peute , Tom H van de Belt , Marlies P. Schijven

Objectives

Upscaling digital solutions is crucial for future-proofing healthcare, yet effective and sustainable methods are underrepresented in literature. In the Netherlands, a University Medical Center (UMC) network collaborated within the Citrien eHealth program to future-proof care using telemonitoring (TM). From 2020–2022, three TM activities were initiated: TM for cardiac rhythm abnormalities/heart failure (TMCardio), TM of blood pressure in high-risk pregnant women (TMAnteNatal), and continuous wireless monitoring of vital functions (TMVitals). This study evaluated the scale-up of these TM programs in seven Dutch UMCs.

Methods

An uncontrolled before-after study design was used.Primary outcome, ‘normalization of telemonitoring,’ was assessed using the 20-item NoMAD questionnaire. Results were structured according to the non-adoption, abandonment, scale-up, spread and sustainability (NASSS) framework. Secondary outcomes included the number of UMCs offering TM programs and the number of patients using TM.

Results

The NoMAD questionnaire had a 61 % response rate. Respondents were familiar with TM (N = 85, mean = 7.27, SD=2.13) and believed it would become more normal in their work (N = 98, mean = 8.42, SD=1.64). However, a significant difference between current practice and expected future use of TM was observed (p≤ 0.001). All UMCs ran TM programs, but not all implemented all three projects. TMCardio patients increased from 190 to 5185, TMAnteNatal from 41 to 1162, and TMVitals from 2666 to 13630.

Conclusion

Telemonitoring uptake increased across Dutch UMCs, but not uniformly. The complexity of scale-up is highest in NASSS domains 4, 5, and 6, with a focus on management, resources, health care reimbursement, and regulations. Understanding the impact of the Citrien network collaboration on scale requires further qualitative analysis.
升级数字解决方案对于面向未来的医疗保健至关重要,但文献中有效和可持续的方法代表性不足。在荷兰,一个大学医学中心(UMC)网络与Citrien eHealth项目合作,使用远程监控(TM)进行面向未来的护理。从2020-2022年,启动三个TM活动:心律异常/心力衰竭TM (TMCardio)、高危孕妇血压TM (tmtenatal)和生命功能连续无线监测(tmvital)。本研究评估了这些TM项目在荷兰七所大学的规模。方法采用前后对照研究设计。主要结果“远程监护的正常化”使用20项NoMAD问卷进行评估。结果根据不采用、放弃、扩大、传播和可持续性(NASSS)框架进行结构化。次要结果包括提供TM项目的UMCs数量和使用TM的患者数量。结果NoMAD问卷有效率为61%。受访者对TM较为熟悉(N = 85,均值= 7.27,SD=2.13),认为TM在工作中会变得更加正常(N = 98,均值= 8.42,SD=1.64)。然而,观察到当前实践和预期未来使用TM之间存在显著差异(p≤0.001)。所有umc都运行TM程序,但并不是所有umc都实现了这三个项目。TMCardio患者从190例增加到5185例,tmmantenatal从41例增加到1162例,TMVitals从2666例增加到13630例。结论远程监护的使用在荷兰各医院有所增加,但并不均匀。扩大规模的复杂性在NASSS领域4、5和6中最高,重点是管理、资源、医疗报销和法规。了解Citrien网络协作对规模的影响需要进一步的定性分析。
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引用次数: 0
Teleconsultation for chronic disease management among community-dwelling older adults: A call for innovation 社区老年人慢性病管理远程会诊:创新的呼唤
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-11-11 DOI: 10.1016/j.hlpt.2025.101131
Su Wei Wan , Lina Choe , Gretel Jianlin Wong , Wee Ling Koh , Janelle Shaina Ng , Wee Hian Tan , Joanna Li Xin Ooi , Jacquelyn Melody , Ker Kan Tan

Objectives

Telehealth services have been around for a while but utilization of teleconsultation among older adults remains low despite its extensive and known benefits. Behavioural intentions are multifactorial and nuanced, and qualitative evidence describing the acceptance of teleconsults for chronic disease management is scarce. Hence, this study explored the perspectives of older adults towards teleconsultation use in the primary care setting.

Methods

A descriptive multi-site qualitative study was conducted. Semi-structured interviews guided by the Unified Theory of Acceptance and Use of Technology (UTAUT) model were held with twenty community-dwelling older adults ≥ 65 years on routine follow-up for three common chronic diseases in Singapore: hypertension, hypercholesterol, and type II diabetes mellitus. Data was analysed using the inductive thematic approach.

Results

Five themes were yielded: (i) more than just a physical consult; (ii) the difference in modes – does it really matter?; (iii) psychological receptivity to new technology; (iv) appropriateness of teleconsultation for medical condition; and (v) moderating factors. Participants were generally ambivalent towards teleconsultation as they could foresee its advantages but also its limitations which were thought to affect treatment. Many lacked knowledge of this remote modality which led to preconceptions of it being non-intuitive and difficult to adopt in the absence of facilitators that promote their viability.

Conclusions

Older adults’ acceptance of teleconsultation for chronic disease management seems conditional and non-optimistic at present. Physician advocacy, digital trainings, structured policies and age-appropriate teleconsult configurations with matured features that can mitigate the shortfalls of remote consultation will help enhance older adults’ acceptance of such services.

Public interest summary

While the potential and proven merits of telemedicine are plentiful, this remote modality remains foreign and intimidating to the majority of older adults. This study explored teleconsult acceptability for chronic disease management with the UTAUT framework. Findings revealed several pressing concerns which indicate the need for more digital initiatives and healthcare advocacy for its uptake in the community. Besides user-related programs, there is room for system improvements to include mature features that may offload the burden on users to learn the technology.
目的远程保健服务已经存在了一段时间,但老年人远程咨询的使用率仍然很低,尽管它有广泛和已知的好处。行为意向是多因素和微妙的,定性证据描述接受远程咨询的慢性病管理是稀缺的。因此,本研究探讨了老年人对远程会诊使用在初级保健设置的观点。方法采用描述性多地点定性研究。在接受和使用技术统一理论(UTAUT)模型的指导下,对20名≥65岁的新加坡社区老年人进行了半结构化访谈,并对高血压、高胆固醇和II型糖尿病这三种常见慢性病进行了常规随访。数据分析采用归纳专题方法。结果产生了五个主题:(i)不仅仅是物理咨询;(ii)模式的差异——这真的重要吗?(iii)对新技术的心理接受能力;(iv)就医疗状况进行远程会诊的适当性;(五)调节因素。参与者通常对远程咨询持矛盾态度,因为他们可以预见其优势,但也可以预见其局限性,这些局限性被认为会影响治疗。许多人对这种远程方式缺乏了解,导致先入为主地认为这种方式不直观,在缺乏促进其可行性的促进者的情况下难以采用。结论目前成人对慢性病远程会诊的接受程度有条件且不容乐观。医生倡导、数字化培训、结构化政策和适合年龄的远程会诊配置,这些成熟的功能可以缓解远程会诊的不足,有助于提高老年人对此类服务的接受度。虽然远程医疗的潜力和已被证明的优点很多,但这种远程模式对大多数老年人来说仍然是陌生的和令人生畏的。本研究探讨远程会诊在UTAUT框架下对慢性病管理的可接受性。调查结果揭示了几个紧迫的问题,表明需要更多的数字举措和医疗保健宣传,以便在社区中采用。除了与用户相关的程序之外,系统还有改进的空间,可以包括成熟的功能,从而减轻用户学习技术的负担。
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