Vascular Endothelial Growth Factor (VEGF), a signaling protein family, is essential in angiogenesis, regulating the growth and survival of endothelial cells that create blood vessels. VEGF is critical in osteogenesis for coordinating blood vessel growth with bone formation, resulting in a well-vascularized environment that promotes nutrition and oxygen delivery to bone-forming cells. Predicting VEGF is crucial, yet experimental methods for identification are both costly and time-consuming. This paper introduces VEGF-ERCNN, an innovative computational model for VEGF prediction using deep learning. Two datasets were generated using primary sequences, and a novel feature descriptor called multi fragmented-position specific scoring matrix-discrete wavelet transformation (MF-PSSM-DWT) was developed to extract numerical characteristics from these sequences. Model training is performed via deep learning techniques such as generative adversarial network (GAN), gated recurrent unit (GRU), ensemble residual convolutional neural network (ERCNN), and convolutional neural network (CNN). The VEGF-ERCNN outperformed other competitive predictors on both training and testing datasets by securing the highest 92.12 % and 83.45 % accuracies, respectively. Accurate prediction of VEGF therapeutic targeting has transformed treatment techniques, establishing it as a crucial participant in both health and disease.
In this work, a system of linear partial differential equations with constant and variable coefficients via Cauchy conditions is handled by applying the numerical algorithm based on operational matrices and equally-spaced collocation points. To demonstrate the applicability and efficiency of the method, four illustrative examples are tested along with absolute error, maximum absolute error, RMS error, and CPU times. The approximate solutions are compared with the analytical solutions and other numerical results in literature. The obtained numerical results are scrutinized by means of tables and graphics. These comparisons show accuracy and productivity of our method for the linear systems of partial differential equations. Besides, an algorithm is described that summarizes the formulation of the presented method. This algorithm can be adapted to well-known computer programs.
Detecting Change Points (CPs) in data sequences is a challenging problem that arises in a variety of disciplines, including signal processing and time series analysis. While many methods exist for PieceWise Constant (PWC) signals, relatively fewer address PieceWise Linear (PWL) signals due to the challenge of preserving sharp transitions. This paper introduces a Markov Random Field (MRF) model for detecting changes in slope. The number of CPs and their locations are unknown. The proposed method incorporates PWL prior information using MRF framework with an additional boolean variable called Line Process (LP), describing the presence or absence of CPs. The solution is then estimated in the sense of maximum a posteriori. The LP allows us to define a non-convex non-smooth energy function that is algorithmically hard to minimize. To tackle the optimization challenge, we propose an extension of the combinatorial algorithm DPS, initially designed for CP detection in PWC signals. Also, we present a shared memory implementation to enhance computational efficiency. Numerical studies show that the proposed model produces competitive results compared to the state-of-the-art methods. We further evaluate the performance of our method on three real datasets, demonstrating superior and accurate estimates of the underlying trend compared to competing methods.
Forest fires are a key component of natural ecosystems, but their increased frequency and intensity have devastating social, economic, and environmental implications. Thus, there is a great need for trustworthy digital tools capable of providing real-time estimates of fire evolution and human interventions. This work develops an interpretable, physics-based model that will serve as the core of a broader wildfire prediction tool. The modeling approach involves a simplified description of combustion kinetics and thermal energy transfer (averaged over local plantation height) and leads to a computationally inexpensive system of differential equations that provides the spatiotemporal evolution of the two-dimensional fields of temperature and combustibles. Key aspects of the model include the estimation of mean wind velocity through the plantation and the inclusion of the effect of ground inclination. Predictions are successfully compared to benchmark literature results concerning the effect of flammable bulk density, moisture content, and the combined influence of wind and slope. Simulations appear to provide qualitatively correct descriptions of firefront propagation from a localized ignition site in a homogeneous or heterogeneous canopy, of acceleration resulting from the collision of oblique firelines, and of firefront overshoot or arrest at fuel break zones.
In the cloud, users need to connect to the data server to perform the file transmission via the Internet, and the Server transmits data to many servers. A machine or vehicle that can fly with the assistance of the air is known as an Aircraft. As an alternative to the downward thrust of jet engines, it uses either static lift or an airfoil's dynamic lift to combat gravity's pull. Drawing wall panel measurement points in the model is easy using the Aircraft Wall Panels (AWP) button. Draw wall panels between existing nodes or on the drawing grid using the relevant wall panel specifications. The technique intends to discover and extract information about undesirable defects such as dents, protrusions, or scratches based on local surface attributes gathered from a 3D scanner. Defects from a perfectly smooth surface include indentations and bumps on the surface. An image's features may be extracted by reducing the number of pixels in the picture to a manageable size so that the most exciting sections of the image can be recorded with Surface Feature Extraction (SFE). Some of the problems are the threat of drones and composite materials that do not break easily in oxymoronic. The aircraft's inner structure may have been damaged, although this is impossible to determine. A runway incursion severely threatens aviation safety because of the rise in aircraft movement on the airport surface and other human factors. An electronic moving map of airport runways and taxiways is shown to the pilot through a head-up display in the cockpit's head-down position. A practical feature extraction approach is required to ensure the safety of the airport scene in runway incursion prevention systems. All the drawbacks are rectified by AWP-SFE sensors installed along the runway centerline to detect magnetic signals generated by surface-moving targets, and this information is utilized to compute the target's length. The target length may extract peak features after regularizing the time domain data. Differentiation of target characteristics is used to determine the similarities between distinct targets. The suggested method's signal characteristics are more easily recognized than time domain or frequency domain feature methods. The experimental results show the proposed method AWP-SE to achieve a high-efficiency ratio of 88.2 %, activity ratio of 73.3 %, Analysis of aircraft in wall plane measurement point of 87.8 % and an error rate of 32.3 % compared to other methods.