Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240638
Xia Philip Q H
Lung cancer is one of the most prominent forms of cancer and ranks as the deadliest of disease afflicting humanity. To tackle this issue, a variety of treatment approaches have been devised to counteract this disease. This review aims to illustrate the mainstream curative and palliative treatment methods in managing non-small cell lung cancer, the most common subtype of lung malignancies.For each treatment method, we have investigated its mechanism, classifications, and techniques involved as well as the clinical success of these treatments. Furthermore, we have also included the reasoning behind each treatment plan, including both quality of life as well as overall survival benefits for the patient.
{"title":"Current available treatments for NSCLC","authors":"Xia Philip Q H","doi":"10.54254/2753-8818/29/20240638","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240638","url":null,"abstract":"Lung cancer is one of the most prominent forms of cancer and ranks as the deadliest of disease afflicting humanity. To tackle this issue, a variety of treatment approaches have been devised to counteract this disease. This review aims to illustrate the mainstream curative and palliative treatment methods in managing non-small cell lung cancer, the most common subtype of lung malignancies.For each treatment method, we have investigated its mechanism, classifications, and techniques involved as well as the clinical success of these treatments. Furthermore, we have also included the reasoning behind each treatment plan, including both quality of life as well as overall survival benefits for the patient.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"45 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240776
Sicheng Xiang
This literature review delves into adolescent criminal psychology and investigates the potential effectiveness of psychological interventions in reducing youth crime. The issue of teenage delinquency is a pressing societal concern with far-reaching consequences. This paper thoroughly examines this complex subject by synthesizing existing literature. The review assesses key findings in adolescent criminal psychology, including the impact of family dynamics and social factors on crime rates. This review sheds light on the multifaceted nature of juvenile delinquency by illuminating the complex interplay of factors that contribute to it. It emphasizes the importance of addressing individual psychological determinants in addition to broader socio-environmental contexts. This literature review explores adolescent criminal psychology and evaluates the effectiveness of psychological interventions in reducing youth crime. The paper provides insights into the psychological underpinnings of childish criminal behavior and the potential strategies for intervention. It delves into the complexity of juvenile delinquency, highlighting the interplay of factors that contribute to it, such as family dynamics, mental health, and social influences. The findings emphasize the importance of addressing these factors to develop more effective approaches to mitigating youth crime.
{"title":"Exploration of adolescent criminal psychology and psychological intervention","authors":"Sicheng Xiang","doi":"10.54254/2753-8818/29/20240776","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240776","url":null,"abstract":"This literature review delves into adolescent criminal psychology and investigates the potential effectiveness of psychological interventions in reducing youth crime. The issue of teenage delinquency is a pressing societal concern with far-reaching consequences. This paper thoroughly examines this complex subject by synthesizing existing literature. The review assesses key findings in adolescent criminal psychology, including the impact of family dynamics and social factors on crime rates. This review sheds light on the multifaceted nature of juvenile delinquency by illuminating the complex interplay of factors that contribute to it. It emphasizes the importance of addressing individual psychological determinants in addition to broader socio-environmental contexts. This literature review explores adolescent criminal psychology and evaluates the effectiveness of psychological interventions in reducing youth crime. The paper provides insights into the psychological underpinnings of childish criminal behavior and the potential strategies for intervention. It delves into the complexity of juvenile delinquency, highlighting the interplay of factors that contribute to it, such as family dynamics, mental health, and social influences. The findings emphasize the importance of addressing these factors to develop more effective approaches to mitigating youth crime.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: This qualitative study investigates the multifaceted experiences of loneliness among elderly residents in long-term care facilities, delving into the intricacies of this pervasive issue. Loneliness is a detrimental issue among this vulnerable group, and understanding its impact on the well-being of older individuals is crucial in that it shows requirements of both humanitarian spirit and traditional moral code. Methods: In this research, a qualitative approach is employed among a diverse group of residents in a certain care home, including in-depth interviews, observational data, and content analysis of personal narratives. Results: Thematic analysis revealed accordingly several common themes related to loneliness, including the common feelings of loneliness, its contributing factors, and individual coping strategies. Conclusion: The findings underscore the complexity of the loneliness experience among the elderly living in care facilities and highlight the need for targeted interventions and policies in long-term care settings to address this significant issue. The insights gained from this research provide valuable information for future policymakers, healthcare providers, and care facility administrators in improving the well-being of elderly residents.
{"title":"Older residents experience of loneliness in nursing homes: A qualitative study","authors":"Mengyao Zhuansun, Lamei Liu, Tong-yao Xu, Yu-meng Qian","doi":"10.54254/2753-8818/29/20240780","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240780","url":null,"abstract":"Aims: This qualitative study investigates the multifaceted experiences of loneliness among elderly residents in long-term care facilities, delving into the intricacies of this pervasive issue. Loneliness is a detrimental issue among this vulnerable group, and understanding its impact on the well-being of older individuals is crucial in that it shows requirements of both humanitarian spirit and traditional moral code. Methods: In this research, a qualitative approach is employed among a diverse group of residents in a certain care home, including in-depth interviews, observational data, and content analysis of personal narratives. Results: Thematic analysis revealed accordingly several common themes related to loneliness, including the common feelings of loneliness, its contributing factors, and individual coping strategies. Conclusion: The findings underscore the complexity of the loneliness experience among the elderly living in care facilities and highlight the need for targeted interventions and policies in long-term care settings to address this significant issue. The insights gained from this research provide valuable information for future policymakers, healthcare providers, and care facility administrators in improving the well-being of elderly residents.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"126 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139629066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240771
Yuhao Du
Scorpions has been existing on earth for hundreds of million years, and its venoms are mostly highly toxic and presents a deadly threat to people around the world. Scorpion venoms are highly complicated cocktails of bioactive components including proteins, amino acids, peptides, and other organic or inorganic molecules. Among them, the main active components are bioactive peptides called neurotoxins. Advancements in research on the toxic mechanisms of common scorpion toxins has found various therapeutic properties of several peptides on a large variety of diseases including different types of cancer and infections. Therefore, scorpion venoms may not only be a threat, but also a valuable source of novel drug components, especially therapeutic peptides. This research gives a brief introduction on scorpions and the components of its venoms, and focuses on presenting current knowledge on the medical effects of neurotoxins in scorpion venom, and potentials applications of the peptides in drug development.
{"title":"Therapeutic effect and potential application of scorpion venom peptide","authors":"Yuhao Du","doi":"10.54254/2753-8818/29/20240771","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240771","url":null,"abstract":"Scorpions has been existing on earth for hundreds of million years, and its venoms are mostly highly toxic and presents a deadly threat to people around the world. Scorpion venoms are highly complicated cocktails of bioactive components including proteins, amino acids, peptides, and other organic or inorganic molecules. Among them, the main active components are bioactive peptides called neurotoxins. Advancements in research on the toxic mechanisms of common scorpion toxins has found various therapeutic properties of several peptides on a large variety of diseases including different types of cancer and infections. Therefore, scorpion venoms may not only be a threat, but also a valuable source of novel drug components, especially therapeutic peptides. This research gives a brief introduction on scorpions and the components of its venoms, and focuses on presenting current knowledge on the medical effects of neurotoxins in scorpion venom, and potentials applications of the peptides in drug development.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"81 S361","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139629502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240825
Tianqi Huang
The COVID-19 pandemic has presented an urgent need to understand the long-term health implications faced by survivors. Post-COVID-19 complications, such as acute kidney injury, arrhythmia, and stroke, pose significant challenges to public health. Despite extensive research on COVID-19 complications, a comprehensive understanding of the risk factors remains elusive due to the potential confounding variables present in the data. Traditional statistical models, while insightful, may not fully capture the causal relationships between these risk factors and post-COVID-19 complications. Motivated by this gap in the literature, we propose a novel approach using causal inference models to predict the likelihood of post-COVID-19 complications based on patient demographics and pre-existing conditions. Our model, trained on a dataset of COVID-19 inpatients in Wuhan Province, China, estimates the causal effect of these factors on the likelihood of patients experiencing post-COVID-19 complications. This approach allows us to isolate the causal impact of each factor while accounting for potential confounders, providing a more accurate understanding of the underlying mechanisms driving these relationships. Unlike traditional models that predict the probability of certain outcomes, our model provides insights into the causal relationships between risk factors and complications, offering a more reliable and comprehensive understanding of the underlying mechanisms. This approach can help identify at-risk patients, inform targeted interventions, and contribute to the development of effective prevention and treatment strategies. Our work aims to contribute to the current understanding of the virus and inform public health policies and interventions.
{"title":"Machine learning drug discovery based on graph neural network and large language model","authors":"Tianqi Huang","doi":"10.54254/2753-8818/29/20240825","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240825","url":null,"abstract":"The COVID-19 pandemic has presented an urgent need to understand the long-term health implications faced by survivors. Post-COVID-19 complications, such as acute kidney injury, arrhythmia, and stroke, pose significant challenges to public health. Despite extensive research on COVID-19 complications, a comprehensive understanding of the risk factors remains elusive due to the potential confounding variables present in the data. Traditional statistical models, while insightful, may not fully capture the causal relationships between these risk factors and post-COVID-19 complications. Motivated by this gap in the literature, we propose a novel approach using causal inference models to predict the likelihood of post-COVID-19 complications based on patient demographics and pre-existing conditions. Our model, trained on a dataset of COVID-19 inpatients in Wuhan Province, China, estimates the causal effect of these factors on the likelihood of patients experiencing post-COVID-19 complications. This approach allows us to isolate the causal impact of each factor while accounting for potential confounders, providing a more accurate understanding of the underlying mechanisms driving these relationships. Unlike traditional models that predict the probability of certain outcomes, our model provides insights into the causal relationships between risk factors and complications, offering a more reliable and comprehensive understanding of the underlying mechanisms. This approach can help identify at-risk patients, inform targeted interventions, and contribute to the development of effective prevention and treatment strategies. Our work aims to contribute to the current understanding of the virus and inform public health policies and interventions.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"81 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139629504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240766
Hongwei Yang
Sickle cell disease is a hereditary blood disease caused by an invisible genetic mutation on the autosome, caused by a transversion mutation in which the 6th amino acid of the -peptide chain, glutamate, is replaced by valine, resulting in the formation of sickle hemoglobin, instead of normal hemoglobin. Due to genetic mutations leading to structural abnormalities in hemoglobin and morphological changes in red blood cells, red blood cells lose their deformability in hypoxic environments, leading to vascular blockage, causing severe pain and partial tissue ischemia in patients. Oxygen needs to be transported to various parts of the body through red blood cells, thereby affecting the transportation of oxygen in the body. In general, red blood cells are circular and elastic, making them easy to move in blood vessels. However, in sickle cells, these red blood cells are compressed and deformed, causing the transportation of oxygen in the blood to become stiff and viscous, potentially slowing or blocking blood flow. The most common complication of SCA is blockage of blood vessels, which leads to pain. Although this is a complex phenomenon, HbS aggregation is a fundamental pathological physiological phenomenon in SCA. HbS aggregation can lead to malignant changes in the shape and physical properties of red blood cells, leading to hemolytic anemia and preventing blood flow, especially in small blood vessels, which may damage some organs. Clinical manifestations include anemia, immunodeficiency, multiple organ damage, severe acute and chronic pain, and premature death. The quality of life of the patients was seriously affected.
{"title":"Treatment of sickle cell anemia using CRISPR and prime editing","authors":"Hongwei Yang","doi":"10.54254/2753-8818/29/20240766","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240766","url":null,"abstract":"Sickle cell disease is a hereditary blood disease caused by an invisible genetic mutation on the autosome, caused by a transversion mutation in which the 6th amino acid of the -peptide chain, glutamate, is replaced by valine, resulting in the formation of sickle hemoglobin, instead of normal hemoglobin. Due to genetic mutations leading to structural abnormalities in hemoglobin and morphological changes in red blood cells, red blood cells lose their deformability in hypoxic environments, leading to vascular blockage, causing severe pain and partial tissue ischemia in patients. Oxygen needs to be transported to various parts of the body through red blood cells, thereby affecting the transportation of oxygen in the body. In general, red blood cells are circular and elastic, making them easy to move in blood vessels. However, in sickle cells, these red blood cells are compressed and deformed, causing the transportation of oxygen in the blood to become stiff and viscous, potentially slowing or blocking blood flow. The most common complication of SCA is blockage of blood vessels, which leads to pain. Although this is a complex phenomenon, HbS aggregation is a fundamental pathological physiological phenomenon in SCA. HbS aggregation can lead to malignant changes in the shape and physical properties of red blood cells, leading to hemolytic anemia and preventing blood flow, especially in small blood vessels, which may damage some organs. Clinical manifestations include anemia, immunodeficiency, multiple organ damage, severe acute and chronic pain, and premature death. The quality of life of the patients was seriously affected.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"68 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240769
Vincent Qijun Chen
Anxiety is a common epidemiological mental disorder that includes Generalized Anxiety Disorder (GAD), panic disorders (PD), and phobias; its causes include anxiogenic genes and the living environment; insufficient or low sleep quality can trigger and intensify anxiety disorders. Neurotransmitters play an essential role in operating our bodys crucial functions, such as emotional regulation and sleep, so much neuroimaging evidence suggests they are critical to forming anxiety and insomnia. Previous longitudinal studies suggest that insomnia is a significant index and predictor of mental health and, therefore, can also be generated from mental disorders due to their comorbidity. This short review will posit the formation of insomnia caused by the presence of anxiety disorders in patients with both insomnia and anxiety symptoms. This review further discusses some therapies that enhance and improve sleep quality among insomnia problems. It mostly debates the thesis that anxiety is the driving factor and precedes insomnia and its related neuropathological developments that can be highlighted from neurotransmitter systems and sleeping models such as the hyperarousal model. Overall, it is significant that individuals with anxiety-related disorders have lower sleeping qualities that cause functional impairment and lower subjective living qualities.
{"title":"The comorbidity of anxiety-related disorders and insomnia: An analysis of mechanisms","authors":"Vincent Qijun Chen","doi":"10.54254/2753-8818/29/20240769","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240769","url":null,"abstract":"Anxiety is a common epidemiological mental disorder that includes Generalized Anxiety Disorder (GAD), panic disorders (PD), and phobias; its causes include anxiogenic genes and the living environment; insufficient or low sleep quality can trigger and intensify anxiety disorders. Neurotransmitters play an essential role in operating our bodys crucial functions, such as emotional regulation and sleep, so much neuroimaging evidence suggests they are critical to forming anxiety and insomnia. Previous longitudinal studies suggest that insomnia is a significant index and predictor of mental health and, therefore, can also be generated from mental disorders due to their comorbidity. This short review will posit the formation of insomnia caused by the presence of anxiety disorders in patients with both insomnia and anxiety symptoms. This review further discusses some therapies that enhance and improve sleep quality among insomnia problems. It mostly debates the thesis that anxiety is the driving factor and precedes insomnia and its related neuropathological developments that can be highlighted from neurotransmitter systems and sleeping models such as the hyperarousal model. Overall, it is significant that individuals with anxiety-related disorders have lower sleeping qualities that cause functional impairment and lower subjective living qualities.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"215 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139628686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240758
Yixuan Gu
The gold standard for diagnosing left ventricular noncompaction evaluated in this article was compared using cardiac magnetic resonance imaging and echocardiography. To generate results, the paper used systematic data analysis techniques such as article screening, data extraction, meta-analysis, and forest plots. Use data gaps exhibited on forest plots to eliminate untrustworthy data, shown here as major gaps with other data, that should be avoided in follow-up investigations. The value of the aforementioned gold standard for diagnosis is as follows. It was discovered that two figures demonstrated the reliability of cMRI, while the other demonstrated that the echocardiograph was more accurate. Two numbers were eliminated because there was no statistically significant difference, and the data p > 0.05. More data integration is still required.
本文评估的诊断左心室非充盈的金标准是通过心脏磁共振成像和超声心动图进行比较。为了得出结果，本文采用了系统的数据分析技术，如文章筛选、数据提取、荟萃分析和森林图。利用森林图上显示的数据差距来剔除不可信的数据，这里显示的是与其他数据的主要差距，在后续调查中应避免使用这些数据。上述金标准的诊断价值如下。我们发现，有两个数字证明了 cMRI 的可靠性，而另一个数字则证明了超声心动图更为准确。由于没有统计学意义上的显著差异，且数据 p > 0.05，因此剔除了两个数字。还需要进行更多的数据整合。
{"title":"Research on the gold criteria of imaging to diagnose left ventricular non-compaction","authors":"Yixuan Gu","doi":"10.54254/2753-8818/29/20240758","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240758","url":null,"abstract":"The gold standard for diagnosing left ventricular noncompaction evaluated in this article was compared using cardiac magnetic resonance imaging and echocardiography. To generate results, the paper used systematic data analysis techniques such as article screening, data extraction, meta-analysis, and forest plots. Use data gaps exhibited on forest plots to eliminate untrustworthy data, shown here as major gaps with other data, that should be avoided in follow-up investigations. The value of the aforementioned gold standard for diagnosis is as follows. It was discovered that two figures demonstrated the reliability of cMRI, while the other demonstrated that the echocardiograph was more accurate. Two numbers were eliminated because there was no statistically significant difference, and the data p > 0.05. More data integration is still required.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"218 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139628677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240797
Xinyi He
Dental caries is a disease which is affected by many factors, mainly bacteria, and eventually leads to the dissolution and damage of the hard tissue of the teeth. Dental caries has become one of the most common diseases affecting children worldwide, and it is on the rise, seriously endangering childrens oral, general and mental health. Traditional clinical treatment methods mainly use filler therapy and root canal therapy, but these are invasive and dependent on patients compliance. There are many therapies that are less invasive and more suitable for children being researched and applied clinically. It is worth noting that for caries, early prevention is more important and effective than late treatment. In recent years, the researches on the pathogenesis and influencing factors of dental caries have also made some progress. This review focuses on the causes, treatment and prevention of dental caries in children, in order to promote the updating of research trends on dental caries in children and to help develop an individualized oral health plan for children.
{"title":"Research on causes, treatment, prevention of dental caries","authors":"Xinyi He","doi":"10.54254/2753-8818/29/20240797","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240797","url":null,"abstract":"Dental caries is a disease which is affected by many factors, mainly bacteria, and eventually leads to the dissolution and damage of the hard tissue of the teeth. Dental caries has become one of the most common diseases affecting children worldwide, and it is on the rise, seriously endangering childrens oral, general and mental health. Traditional clinical treatment methods mainly use filler therapy and root canal therapy, but these are invasive and dependent on patients compliance. There are many therapies that are less invasive and more suitable for children being researched and applied clinically. It is worth noting that for caries, early prevention is more important and effective than late treatment. In recent years, the researches on the pathogenesis and influencing factors of dental caries have also made some progress. This review focuses on the causes, treatment and prevention of dental caries in children, in order to promote the updating of research trends on dental caries in children and to help develop an individualized oral health plan for children.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"149 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139629118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-08DOI: 10.54254/2753-8818/29/20240751
Yinxi Zhang
As humans develop, science is also rapidly evolving, and biological science and medical support are vital for humans need. The development of biology has been particularly important. It stretches from the initial understanding of plants and animals to human biology and micro molecular biology, from macro understanding of life to micro molecular biology. Although it has accumulated a lot of knowledge about biology, it still has many unknowns about this giant and precise system. However, in recent years, a new interdisciplinary and emerging discipline has greatly opened up peoples understanding about biological information-bioinformatics. The most fundamental research target of bioinformatics is different sequences. The most important is the amino acid sequence of proteins and the base sequence of DNA. To study sequences and their constituent components, bioinformatics has another major research target - the biological database. This involves analysing the structure, connotation, and function of biological information through basic protein and nucleic acid sequences. Therefore, bioinformatics has made tremendous applications in the medical field. This research mainly analyzes and discusses the advantages and disadvantages of the application of bioinformatics in the medical field.
随着人类的发展，科学也在飞速发展，生物科学和医疗支持对人类的需求至关重要。生物学的发展尤为重要。它从最初对动植物的认识延伸到人类生物学和微观分子生物学，从对生命的宏观认识延伸到微观分子生物学。虽然积累了大量的生物学知识，但对于这个庞大而精密的系统，仍有许多未知。然而，近年来，一门新兴的交叉学科--生物信息学极大地开拓了人们对生物信息的认识。生物信息学最基本的研究对象是不同的序列。最重要的是蛋白质的氨基酸序列和 DNA 的碱基序列。为了研究序列及其组成成分，生物信息学的另一个主要研究目标是生物数据库。这包括通过基本蛋白质和核酸序列分析生物信息的结构、内涵和功能。因此，生物信息学在医学领域得到了极大的应用。本研究主要分析和讨论生物信息学在医学领域应用的优势和劣势。
{"title":"Analysis of the application of bioinformatics in the medicine","authors":"Yinxi Zhang","doi":"10.54254/2753-8818/29/20240751","DOIUrl":"https://doi.org/10.54254/2753-8818/29/20240751","url":null,"abstract":"As humans develop, science is also rapidly evolving, and biological science and medical support are vital for humans need. The development of biology has been particularly important. It stretches from the initial understanding of plants and animals to human biology and micro molecular biology, from macro understanding of life to micro molecular biology. Although it has accumulated a lot of knowledge about biology, it still has many unknowns about this giant and precise system. However, in recent years, a new interdisciplinary and emerging discipline has greatly opened up peoples understanding about biological information-bioinformatics. The most fundamental research target of bioinformatics is different sequences. The most important is the amino acid sequence of proteins and the base sequence of DNA. To study sequences and their constituent components, bioinformatics has another major research target - the biological database. This involves analysing the structure, connotation, and function of biological information through basic protein and nucleic acid sequences. Therefore, bioinformatics has made tremendous applications in the medical field. This research mainly analyzes and discusses the advantages and disadvantages of the application of bioinformatics in the medical field.","PeriodicalId":489336,"journal":{"name":"Theoretical and Natural Science","volume":"78 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139629194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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