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Ultrasound guided stellate ganglion block for the treatment of tinnitus. 超声引导下的星状神经节阻滞治疗耳鸣。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-03-28 DOI: 10.1177/09287329251324068
Xiaolan Qian, Liqing Zhao, Qiying Wang, Dingguo Liu, Gaigai Ma

BackgroundTinnitus, a common auditory disorder, significantly impacts patient quality of life and lacks universally effective treatments. The integration of advanced imaging technology like ultrasound in therapeutic interventions offers new possibilities in healthcare.ObjectiveThis study evaluated the efficacy of ultrasound-guided stellate ganglion block as an innovative approach to managing tinnitus.MethodsEighty patients with tinnitus were randomly assigned to either a control group receiving standard drug therapy or an observation group treated with ultrasound-guided stellate ganglion block in addition to standard therapy. Key metrics, including clinical effectiveness rates, anxiety scores, and tinnitus disability index scores, were assessed pre- and post-treatment.ResultsPost-treatment outcomes revealed that the observation group exhibited significantly improved anxiety scores (38.74 ± 4.05 vs. 50.45 ± 4.86; P < 0.05) and tinnitus disability index scores (37.8 ± 17.56 vs. 50.4 ± 21.26; P < 0.05) compared to the control group. Additionally, the observation group achieved a 100% clinical efficacy rate, outperforming the control group's 84% (P < 0.05).ConclusionUltrasound-guided stellate ganglion block demonstrates superior efficacy in managing tinnitus compared to conventional drug therapy. This study underscores the potential of integrating advanced ultrasound technology into healthcare to optimize treatment outcomes for auditory disorders.

耳鸣是一种常见的听觉障碍,严重影响患者的生活质量,缺乏普遍有效的治疗方法。超声等先进成像技术在治疗干预中的整合为医疗保健提供了新的可能性。目的探讨超声引导下星状神经节阻滞治疗耳鸣的新方法。方法将80例耳鸣患者随机分为对照组和观察组,对照组采用标准药物治疗,观察组在标准治疗的基础上采用超声引导星状神经节阻滞治疗。评估治疗前后的关键指标,包括临床有效率、焦虑评分和耳鸣残疾指数评分。结果治疗后观察组患者焦虑评分显著提高(38.74±4.05∶50.45±4.86;P
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引用次数: 0
Deep learning-based decision support system for cervical cancer identification in liquid-based cytology pap smears. 基于深度学习的宫颈细胞学涂片宫颈癌识别决策支持系统。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-04-30 DOI: 10.1177/09287329251330081
Ghada Atteia, Maali Alabdulhafith, Hanaa A Abdallah, Nagwan Abdel Samee, Walaa Alayed

BackgroundCervical cancer is the fourth most common cause of women cancer deaths worldwide. The primary etiology of cervical cancer is the persistent infection of specific high-risk strains of the human papillomavirus. Liquid-based cytology is the established method for early detection of cervical cancer. The evaluation of cellular abnormalities at a microscopic level allows for the identification of malignant or precancerous features in liquid-based cytology pap smears. This technique is characterized by its time-consuming nature and susceptibility to both inter- and intra-observer variability. Hence, the utilization of Artificial Intelligence in computer-assisted diagnosis can reduce the duration needed for diagnosing this ailment, thereby eliminating delayed diagnosis and facilitating the implementation of an efficient treatment.ObjectiveThis research presents a new deep learning-based cervical cancer identification decision support system in liquid-based cytology smear images.MethodsThe proposed diagnosis support system incorporates a novel hybrid feature reduction and optimization module, which integrates a sparse Autoencoder with the Binary Harris Hawk metaheuristic optimization algorithm to select the most informative features from a supplemented feature set of the input images. The supplemented feature set is retrieved by three pretrained Convolutional Neural Networks. The module utilizes an improved feature set to conduct a Bayesian-optimized K Nearest Neighbors machine learning classification of cervical cancer in input Pap smears.ResultsThe introduced approach achieves a classification accuracy of 99.9% and demonstrates an improved ability to detect the stages of cervical cancer, with a sensitivity of 99.8%. In addition, the system has the ability to identify the lack of cervical cancer stages with a specificity rate of 99.9%.ConclusionThe proposed system outpaces recent deep learning-based cervical cancer identification systems.

背景宫颈癌是全球第四大女性癌症死亡原因。宫颈癌的主要病因是人类乳头瘤病毒特定高危株的持续感染。液体细胞学检查是宫颈癌早期检测的常用方法。在显微镜水平上对细胞异常的评估允许在液体细胞学巴氏涂片中识别恶性或癌前特征。该技术的特点是耗时,易受观察者之间和内部变化的影响。因此,在计算机辅助诊断中使用人工智能可以减少诊断这种疾病所需的时间,从而消除延误的诊断,促进有效治疗的实施。目的研究一种新的基于深度学习的细胞学涂片图像宫颈癌识别决策支持系统。方法提出的诊断支持系统采用了一种新型的混合特征约简和优化模块,该模块将稀疏自编码器与二进制Harris Hawk元启发式优化算法集成在一起,从补充的输入图像特征集中选择信息量最大的特征。补充的特征集由三个预训练的卷积神经网络检索。该模块利用改进的特征集对输入子宫颈抹片检查中的宫颈癌进行贝叶斯优化的K近邻机器学习分类。结果该方法的分类准确率为99.9%,对宫颈癌分期的检测能力提高,灵敏度为99.8%。此外,该系统具有识别宫颈癌分期不足的能力,特异性率为99.9%。结论该系统优于目前基于深度学习的宫颈癌识别系统。
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引用次数: 0
Brain tumor detection using hybrid transfer learning and patch antenna-enhanced microwave imaging. 混合迁移学习和贴片天线增强微波成像的脑肿瘤检测。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-04-10 DOI: 10.1177/09287329251325740
Deebu Usha Sudhakaran, Sreeja Thanka Swami Kanaka Bai

BackgroundBrain tumors pose a significant healthcare challenge, necessitating early detection and precise monitoring to ensure effective treatment.ObjectivesThe study proposes an innovative technique with the integration of hybrid transfer learning with improved microwave imaging. The integration of special feature extraction abilities of pre-trained deep learning methods along with the high-resolution imaging capabilities of the patch antenna.MethodsIt was primarily composed of two phases. The initial stage involves the development of a patch antenna and head phantom model, which are then subjected to SAR analysis to extract pertinent features from transmitted signals. In the second stage, an AI-based detection model that utilizes MobileNet V2 is implemented. The images acquired by the patch antenna system are fed into MobileNet V2, which extracts high-level features by employing depth-wise separable convolutions and inverted residual blocks. The fully connected layer is used to classify brain tumors in an effective manner by passing these extracted features.ResultsThe results of the simulation indicate that the model performs exceptionally well, with an accuracy of 98.44%, precision of 98.03%, recall of 99.00%, F1-score of 98.52%, and specificity of 97.82%.ConclusionThis method offers a promising solution for the non-invasive and real-time detection of brain tumors, taking advantage of the electromagnetic properties of brain tissue and the capabilities of AI to address the limitations of current diagnostic methods, such as MRI and CT scans.

脑肿瘤是一项重大的医疗挑战,需要早期发现和精确监测以确保有效治疗。目的提出一种将混合迁移学习与改进的微波成像相结合的创新技术。将预先训练的深度学习方法的特殊特征提取能力与贴片天线的高分辨率成像能力相结合。方法主要分为两个阶段。初始阶段包括开发贴片天线和头部幻影模型,然后对其进行SAR分析,以从传输信号中提取相关特征。在第二阶段,实现了利用MobileNet V2的基于人工智能的检测模型。将贴片天线系统获取的图像输入到MobileNet V2中,MobileNet V2通过采用深度可分卷积和反向残差块提取高级特征。全连接层通过传递这些提取的特征,对脑肿瘤进行有效的分类。结果仿真结果表明,该模型的准确率为98.44%,精密度为98.03%,召回率为99.00%,f1评分为98.52%,特异性为97.82%。结论该方法利用脑组织的电磁特性和人工智能的能力,解决了MRI和CT扫描等现有诊断方法的局限性,为脑肿瘤的无创实时检测提供了一种很有前景的解决方案。
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引用次数: 0
Experience with a team-based gamification health app for behavior change adapted to people with diabetes: A pilot study. 基于团队的游戏化健康应用程序的经验,用于糖尿病患者的行为改变:一项试点研究。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-04-30 DOI: 10.1177/09287329251332454
Satoshi Inagaki, Kenji Kato, Tomokazu Matsuda, Kozue Abe, Shogo Kurebayashi, Masatomo Mihara, Daisuke Azuma, Michinori Takabe, Yasuhisa Abe, Hisafumi Yasuda

BackgroundHealth apps offer promising support for people with diabetes; however, the retention rates are low. Team-based apps and gamification can increase engagement and contribute to sustained use.ObjectiveThis pilot study explored how a team-based gamification app can support diabetes self-care.MethodsIndividuals with diabetes were introduced to a team-based gamification app that encourages the development of new habits. After 6 weeks of use, participants completed a questionnaire on system satisfaction, ease of use, enjoyment, usefulness for self-care, and burden, using a five-point scale. Qualitative data were also collected.ResultsOf the 32 participants, 65% were satisfied, 81% found it useful for lifestyle management, and 71% found it useful for exercise. The team system and challenge-tracking features were the most useful. Participants stated that the app provided emotional support and motivated healthy habits through social comparison; however, they also reported confusion in aligning team and individual needs.ConclusionsThe team-based gamification health app provided emotional support by team members who shared the same goals and motivated healthy lifestyle habits through social comparison.

健康应用程序为糖尿病患者提供了有希望的支持;然而,留存率很低。基于团队的应用和游戏化可以提高用户粘性并促进持续使用。目的:本初步研究探讨基于团队的游戏化应用程序如何支持糖尿病患者的自我护理。方法将糖尿病患者引入以团队为基础的游戏化应用程序,鼓励他们养成新习惯。使用6周后,参与者完成一份关于系统满意度、易用性、享受、自我护理有用性和负担的调查问卷,采用五分制。定性资料也被收集。结果在32名参与者中,65%的人满意,81%的人认为它对生活方式管理有用,71%的人认为它对锻炼有用。团队系统和挑战追踪功能是最有用的。参与者表示,该应用程序通过社会比较提供了情感支持并激发了健康习惯;然而,他们也报告了在协调团队和个人需求方面的混乱。结论基于团队的游戏化健康app为目标相同的团队成员提供情感支持,并通过社会比较激励健康的生活习惯。
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引用次数: 0
Comprehensive lifecycle quality control of medical data - automated monitoring and feedback mechanisms based on artificial intelligence. 医疗数据全生命周期质量控制——基于人工智能的自动监测与反馈机制。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-04-16 DOI: 10.1177/09287329251330222
Haixia Liu, Zhanju Li, Zijian Song

BackgroundDigital healthcare's advance has underscored an urgent requirement for solid medical record quality control, critical for data integrity, surpassing manual methods' inadequacies.ObjectiveThe goal was to develop an AI system to manage medical record quality control comprehensively, using advanced AI like reinforcement learning and NLP to boost management's precision and efficiency.MethodsThis AI system uses a closed-loop framework for real-time record review using natural language processing techniques and reinforcement learning, synchronized with the hospital information system. It features a data layer for monitoring, a service layer for AI analysis, and a presentation layer for user engagement. Its impact was evaluated by comparing quality metrics pre- and post-deployment.ResultsWith the AI system, quality control became fully operational, with review times per record plummeting from 4200 s to 2 s. The share of Grade A records rose from 89.43% to 99.21%, and the system markedly minimized formal and substantive record errors, enhancing completeness and accuracy. The implementation of the artificial intelligence-based medical record quality control system optimizes the quality control process, dynamically regulates the diagnostic behavior of medical staff, and promotes the standardization and normalization of clinical medical record writing.ConclusionsThe AI-driven system significantly upgraded the management of medical records in terms of efficiency and accuracy. It provides a scalable approach for hospitals to refine quality control, propelling healthcare towards heightened intelligence and automation, and foreshadowing AI's pivotal role in future healthcare quality management.

数字医疗保健的进步凸显了对可靠的医疗记录质量控制的迫切需求,这对数据完整性至关重要,超越了手工方法的不足。目的开发一套全面管理病案质量控制的人工智能系统,利用强化学习和自然语言处理等先进人工智能技术,提高管理的精度和效率。方法该人工智能系统采用闭环框架,采用自然语言处理技术和强化学习,与医院信息系统同步进行实时病历审核。它有一个用于监控的数据层、一个用于人工智能分析的服务层和一个用于用户参与的表示层。通过比较部署前和部署后的质量指标来评估其影响。有了人工智能系统,质量控制变得全面运作,每个记录的审查时间从4200秒下降到2秒。A级档案比例从89.43%上升到99.21%,系统显著减少了形式和实质性档案错误,提高了完整性和准确性。基于人工智能的病案质量控制系统的实施,优化了质量控制流程,动态规范了医务人员的诊断行为,促进了临床病案编写的规范化和规范化。结论人工智能驱动的系统在效率和准确性方面显著提升了病案管理的水平。它为医院提供了一种可扩展的方法来完善质量控制,推动医疗保健向高度智能化和自动化发展,并预示着人工智能在未来医疗保健质量管理中的关键作用。
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引用次数: 0
Application of magnetic navigation for pediatric PICC placement: A retrospective study. 磁导航在儿童PICC放置中的应用:一项回顾性研究。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-06-04 DOI: 10.1177/09287329251347875
Qiong Chen, Yanchao Li, Huihuan Zhu, Qiaoru Li

Background: Peripherally Inserted Central Catheters (PICC) are widely used for long-term intravenous therapy in pediatric patients and are effective in preventing catheter displacement.

Objective: This study aimed to investigate the effect of magnetic navigation technology compared with ultrasound imaging and manual control of the catheter path.

Methods: The control group underwent PICC placement using the Seldinger technique under ultrasound guidance (n = 86), while the magnetic navigation group received magnet-assisted PICC placement (n = 80). Both groups used chest X-ray (CXR) after catheter placement to confirm the tip position. Insertion time, first-attempt success rate, complication rate, post-procedural pain, post-procedural anxiety, and family satisfaction were compared.

Results: Compared to the control group, magnetic navigation significantly reduced catheter insertion time (28.2 ± 3.67 min vs. 34.85 ± 2.94 min, P < 0.001), improved first-attempt success rate (91.25% vs. 41.86%, P < 0.001), and lowered the complication rate (21.25% vs. 66.28%, P < 0.001). In addition, magnetic navigation alleviated post-procedural pain and anxiety (P < 0.01), and improved family satisfaction (P < 0.01).

Conclusion: Compared to traditional ultrasound-guided methods, magnetic navigation offers superior efficiency in pediatric PICC placement, highlighting its promising potential for clinical application and broader implementation.

背景:外周置管中心导管(PICC)广泛用于儿科患者的长期静脉治疗,可有效防止导管移位。目的:本研究旨在探讨磁导技术与超声成像和人工控制导管路径的效果。方法:对照组采用超声引导下Seldinger技术放置PICC (n = 86),磁导航组采用磁体辅助放置PICC (n = 80)。两组患者置管后均行x线胸片(CXR)确认导管尖端位置。比较插入时间、首次尝试成功率、并发症发生率、术后疼痛、术后焦虑和家属满意度。结果:与对照组相比,磁导航明显缩短了置管时间(28.2±3.67 min vs. 34.85±2.94 min) P P P P P结论:与传统超声引导方法相比,磁导航在小儿PICC置管中具有更高的效率,具有广阔的临床应用前景和推广价值。
{"title":"Application of magnetic navigation for pediatric PICC placement: A retrospective study.","authors":"Qiong Chen, Yanchao Li, Huihuan Zhu, Qiaoru Li","doi":"10.1177/09287329251347875","DOIUrl":"10.1177/09287329251347875","url":null,"abstract":"<p><strong>Background: </strong>Peripherally Inserted Central Catheters (PICC) are widely used for long-term intravenous therapy in pediatric patients and are effective in preventing catheter displacement.</p><p><strong>Objective: </strong>This study aimed to investigate the effect of magnetic navigation technology compared with ultrasound imaging and manual control of the catheter path.</p><p><strong>Methods: </strong>The control group underwent PICC placement using the Seldinger technique under ultrasound guidance (n = 86), while the magnetic navigation group received magnet-assisted PICC placement (n = 80). Both groups used chest X-ray (CXR) after catheter placement to confirm the tip position. Insertion time, first-attempt success rate, complication rate, post-procedural pain, post-procedural anxiety, and family satisfaction were compared.</p><p><strong>Results: </strong>Compared to the control group, magnetic navigation significantly reduced catheter insertion time (28.2 ± 3.67 min vs. 34.85 ± 2.94 min, <i>P</i> < 0.001), improved first-attempt success rate (91.25% vs. 41.86%, <i>P</i> < 0.001), and lowered the complication rate (21.25% vs. 66.28%, <i>P</i> < 0.001). In addition, magnetic navigation alleviated post-procedural pain and anxiety (<i>P</i> < 0.01), and improved family satisfaction (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Compared to traditional ultrasound-guided methods, magnetic navigation offers superior efficiency in pediatric PICC placement, highlighting its promising potential for clinical application and broader implementation.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"2386-2393"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D transesophageal echocardiography has benefits in the diagnosis and prognosis of patients with infectious endocarditis. 三维经食管超声心动图对感染性心内膜炎的诊断和预后有一定的价值。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-04-27 DOI: 10.1177/09287329251327473
Zorica Mladenovic, Gordana Milic, Predrag Djuric, Zoran Jovic, Vesna Begovic, Nikolina Ciric, Ivica Djuric, Marko Dincic, Slobodan Jankovic, Edin Begic

Introduction: Infective endocarditis (IE), despite advancements in diagnostic and therapeutic strategies, remains a life-threatening condition with high in-hospital mortality. The aim of this study was to assess an importance of a different echocardiographic techniques in the evaluation of patients with IE.

Methods: This prospective study included all consecutive patients hospitalized with a diagnosis of IE. Each patient underwent both 2D transesophageal echocardiography (2DTOE) and 3D transesophageal echocardiography (3DTOE) as part of the initial diagnostic evaluation. Laboratory results, isolated pathogens, and monitoring during hospitalization were also taken into account.

Results: The study included 59 patients (69.49% male, mean age 64.4 ± 16.0). Native valve endocarditis (NVE) was present in 32 (54.24%), prosthetic valve endocarditis (PVE) in 17 (28.81%), and cardiac device-related IE (CDIE) in 10 (16.95%). Blood cultures were positive in 72.4% of cases, with Enterococcus faecalis predominant in NVE, and Staphylococcus species in PVE (S. epidermidis) and CDIE (S. aureus) (p = 0.039). TOE provided detailed imaging, detecting more lesions, with 3D TOE excelling in identifying destructive lesions, particularly perforations (p < 0.001). Vegetations were most frequent in NVE and CDIE, while destructive lesions were more common in PVE (p < 0.05). 3D TOE identified longer vegetations and more destructive lesions, especially in PVE (p < 0.05).

Conclusion: 3D TOE, provide a detailed real time imaging, and could be considered as key adjunctive modality in practice when the cardiac anatomy is not precisely visualized by 2D TOE, particularly when advanced surgical planning is required.

感染性心内膜炎(IE),尽管在诊断和治疗策略的进步,仍然是一个危及生命的疾病,在医院死亡率高。本研究的目的是评估不同超声心动图技术在评估IE患者中的重要性。方法本前瞻性研究纳入所有诊断为IE的连续住院患者。每例患者均行二维经食管超声心动图(2DTOE)和三维经食管超声心动图(3DTOE)作为初步诊断评估的一部分。还考虑了实验室结果、分离的病原体和住院期间的监测。结果纳入59例患者,其中男性69.49%,平均年龄64.4±16.0岁。先天性瓣膜心内膜炎(NVE) 32例(54.24%),人工瓣膜心内膜炎(PVE) 17例(28.81%),心脏装置相关性IE (CDIE) 10例(16.95%)。72.4%的病例血培养阳性,NVE以粪肠球菌为主,PVE以表皮葡萄球菌和CDIE葡萄球菌为主(p = 0.039)。TOE提供了详细的成像,可以检测到更多的病变,3D TOE擅长识别破坏性病变,特别是穿孔
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引用次数: 0
Assessing the impact of chatbots on health decision-making: A multifactorial experimental approach. 评估聊天机器人对健康决策的影响:一种多因素实验方法。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-05-15 DOI: 10.1177/09287329251341071
Zehang Xie

BackgroundChatbots are increasingly integrated into healthcare, offering personalized and accessible health advice. However, the impact of factors such as chatbot authority, health information type, and interaction style on users' decision-making remains unclear.ObjectiveThis study aims to investigate how these elements influence users' willingness to adopt health advice provided by chatbots.MethodsA 2 × 2 × 2 factorial experiment was conducted with 480 university students to examine the effects of chatbot authority (authoritative vs. non-authoritative), health information type (preventive vs. treatment-related), and interaction style (formal vs. informal). Participants' willingness to adopt the health advice was measured before and after interacting with the chatbot.ResultsThe study found that a authoritative chatbot delivering treatment-related advice in a formal style significantly increased willingness to adopt the advice. Conversely, preventive information was more effective when presented informally by a non-authoritative chatbot. These results support the media evocation paradigm, which suggests that chatbots framed as authoritative figures evoke greater user engagement and trust in health contexts.ConclusionThe findings extend the media evocation paradigm by demonstrating that chatbot authority, information type, and interaction style should be aligned with the nature of health advice to maximize effectiveness. This study provides insights for designing chatbots that improve health decision-making by tailoring their communication strategies.

聊天机器人越来越多地融入医疗保健领域,提供个性化和可访问的健康建议。然而,诸如聊天机器人权限、健康信息类型和交互方式等因素对用户决策的影响尚不清楚。目的本研究旨在探讨这些因素如何影响用户接受聊天机器人提供的健康建议的意愿。方法对480名大学生进行2 × 2 × 2因子实验,考察聊天机器人权威(权威与非权威)、健康信息类型(预防与治疗相关)、互动方式(正式与非正式)的影响。参与者接受健康建议的意愿在与聊天机器人互动之前和之后被测量。研究发现,一个权威的聊天机器人以正式的方式提供与治疗相关的建议,显著增加了接受建议的意愿。相反,由非权威的聊天机器人非正式地提供预防性信息更有效。这些结果支持媒体唤起范式,该范式表明,作为权威人物的聊天机器人在健康环境中唤起了更大的用户参与和信任。结论通过证明聊天机器人的权威、信息类型和交互风格应该与健康建议的性质保持一致,以最大限度地提高效果,这些发现扩展了媒体唤起范式。这项研究为设计聊天机器人提供了见解,这些聊天机器人可以通过定制沟通策略来改善健康决策。
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引用次数: 0
Research on CT image segmentation and classification of liver tumors based on attention mechanism and improved U-Net model. 基于注意机制和改进U-Net模型的肝脏肿瘤CT图像分割分类研究。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-04-30 DOI: 10.1177/09287329251329294
Guang Mei, Jinhua Yu

BackgroundLiver cancer is still one of the most common causes of death from cancer globally. The accurate segmentation of liver tumors from CT images is critical for diagnosis, treatment planning, and tracking. Conventional segmentation techniques frequently struggle to handle the intricacy of medical images, requiring the usage of sophisticated artificial intelligence (AI) methods to enhance accuracy and effectiveness.ObjectiveThe main objective of this study is to create and test an improved U-Net model (AM-UNet) that incorporates an attention mechanism to enhance the segmentation and classification accuracy of liver tumors in CT images. This method seeks to surpass previous techniques in terms of accuracy, precision, recall, and F1 score.MethodsThe dataset used includes 194 liver tumor CT scans obtained from 131 individuals for training and 70 for testing. The open-source 3DIRCAD-B dataset, which is incorporated into LiTS, contains images of both normal and pathological conditions. Preprocessing methods such as Median Filtering (MF) and Histogram Equalization (HE) were used to reduce noise and improve contrast. The AM-UNet model was then used to segment the tumors before classifying them as malignant or benign. The efficiency was assessed utilizing metrics like accuracy, precision, recall, F1-score, and ROC (Receiver Operating Characteristic).ResultsThe suggested AM-UNet model produced excellent outcomes, with a recall of 95%, accuracy of 92%, precision of 94%, and an F1-score of 93%. These metrics show that the model outperforms conventional techniques in correctly segmenting and classifying liver tumors in CT images.ConclusionThe AM-UNet model improves the segmentation and classification of liver tumors, providing substantial performance metrics over traditional methods. Its utilization can transform liver cancer diagnosis by assisting physicians in accurate tumor identification and treatment planning, resulting in improved patient results.

背景肝癌仍然是全球最常见的癌症死亡原因之一。从CT图像中准确分割肝脏肿瘤对于诊断、治疗计划和跟踪至关重要。传统的分割技术往往难以处理医学图像的复杂性,需要使用复杂的人工智能(AI)方法来提高准确性和有效性。本研究的主要目的是建立和测试一种改进的U-Net模型(AM-UNet),该模型结合了注意机制,以提高CT图像中肝脏肿瘤的分割和分类精度。该方法力求在准确性、精密度、召回率和F1分数方面超越以往的技术。方法使用的数据集包括194个肝肿瘤CT扫描,其中131个用于训练,70个用于测试。开源的3DIRCAD-B数据集包含了正常和病理状态的图像。采用中值滤波(MF)和直方图均衡化(HE)等预处理方法降低噪声,提高对比度。然后使用AM-UNet模型对肿瘤进行分割,然后将其分类为恶性或良性。利用准确度、精密度、召回率、f1评分和ROC(受试者工作特征)等指标评估效率。结果提出的AM-UNet模型取得了很好的结果,召回率为95%,准确率为92%,精密度为94%,f1评分为93%。这些指标表明,该模型在CT图像中正确分割和分类肝脏肿瘤方面优于传统技术。结论AM-UNet模型改进了肝脏肿瘤的分割和分类,比传统方法提供了实质性的性能指标。利用它可以改变肝癌的诊断,帮助医生准确识别肿瘤和制定治疗计划,从而改善患者的治疗效果。
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引用次数: 0
Data-driven analysis of technological biomarkers and functional myocardial ischemia in stable coronary artery disease using advanced statistical modeling. 采用先进的统计模型对稳定型冠状动脉疾病的技术生物标志物和功能性心肌缺血进行数据驱动分析。
IF 1.8 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2025-09-01 Epub Date: 2025-04-29 DOI: 10.1177/09287329251333873
Cheng Cheng, Yan Li, Yifang Huang, Bei Du

Background: Functional myocardial ischemia (FMI) in stable coronary artery disease (SCAD) remains a critical challenge in cardiovascular care. While fractional flow reserve (FFR) is a gold-standard diagnostic technology, its clinical adoption is limited by cost and complexity. Integrating technological biomarkers and advanced analytics could enhance risk stratification and guide precision interventions.

Objective: This study leverages data-driven methodologies to identify and validate technological biomarkers associated with FMI in SCAD, aiming to optimize clinical decision-making through predictive modeling.

Methods: A systematic search across PubMed, Embase, and Web of Science (inception-October 2023) identified studies evaluating SCAD and FMI.

Inclusion criteria: cohort/case-control studies (n ≥ 100) using FFR or angiographic technologies. Meta-analyses were conducted via RevMan 5.4 and Stata 16.0, employing fixed/random-effects models. Heterogeneity was assessed using I² statistics.

Results: Analysis of 15 studies (n = 4854) revealed that anatomical biomarkers-stenosis severity (DS%: SMD = 0.95, p < 0.0001), minimal lumen diameter (SMD = -1.33, p < 0.0001), and lesion length (SMD = 0.72, p < 0.0001)-were strongly linked to FMI. Diabetes (OR = 1.31, p = 0.003) and smoking (OR = 1.47, p < 0.0001) emerged as significant modifiable risks, while hypertension showed no association (p = 0.14). Age and gender disparities highlighted the need for personalized risk algorithms.

Conclusion: Technological biomarkers and data-driven modeling provide actionable insights into FMI risk in SCAD, bridging gaps between anatomical assessments and functional outcomes. Future integration of machine learning and predictive analytics could refine risk stratification, enabling tailored therapeutic strategies.

背景:稳定性冠状动脉疾病(SCAD)的功能性心肌缺血(FMI)仍然是心血管护理的一个关键挑战。虽然部分血流储备(FFR)是一种金标准诊断技术,但其临床应用受到成本和复杂性的限制。整合技术生物标志物和先进的分析可以增强风险分层和指导精确干预。目的本研究利用数据驱动的方法来识别和验证与SCAD FMI相关的技术生物标志物,旨在通过预测建模优化临床决策。方法系统检索PubMed, Embase和Web of Science(启动- 2023年10月),确定评估SCAD和FMI的研究。纳入标准:采用FFR或血管造影技术的队列/病例对照研究(n≥100)。meta分析采用RevMan 5.4和Stata 16.0进行,采用固定/随机效应模型。采用I²统计量评估异质性。结果15项研究(n = 4854)的解剖生物标志物-狭窄严重程度(DS%: SMD = 0.95, p p p = 0.003)和吸烟(OR = 1.47, p p = 0.14)。年龄和性别差异突出了个性化风险算法的必要性。技术生物标志物和数据驱动建模为SCAD FMI风险提供了可行的见解,弥合了解剖评估和功能结果之间的差距。未来机器学习和预测分析的整合可以完善风险分层,实现量身定制的治疗策略。
{"title":"Data-driven analysis of technological biomarkers and functional myocardial ischemia in stable coronary artery disease using advanced statistical modeling.","authors":"Cheng Cheng, Yan Li, Yifang Huang, Bei Du","doi":"10.1177/09287329251333873","DOIUrl":"10.1177/09287329251333873","url":null,"abstract":"<p><strong>Background: </strong>Functional myocardial ischemia (FMI) in stable coronary artery disease (SCAD) remains a critical challenge in cardiovascular care. While fractional flow reserve (FFR) is a gold-standard diagnostic technology, its clinical adoption is limited by cost and complexity. Integrating technological biomarkers and advanced analytics could enhance risk stratification and guide precision interventions.</p><p><strong>Objective: </strong>This study leverages data-driven methodologies to identify and validate technological biomarkers associated with FMI in SCAD, aiming to optimize clinical decision-making through predictive modeling.</p><p><strong>Methods: </strong>A systematic search across PubMed, Embase, and Web of Science (inception-October 2023) identified studies evaluating SCAD and FMI.</p><p><strong>Inclusion criteria: </strong>cohort/case-control studies (n ≥ 100) using FFR or angiographic technologies. Meta-analyses were conducted via RevMan 5.4 and Stata 16.0, employing fixed/random-effects models. Heterogeneity was assessed using I² statistics.</p><p><strong>Results: </strong>Analysis of 15 studies (n = 4854) revealed that anatomical biomarkers-stenosis severity (DS%: SMD = 0.95, <i>p</i> < 0.0001), minimal lumen diameter (SMD = -1.33, <i>p</i> < 0.0001), and lesion length (SMD = 0.72, <i>p</i> < 0.0001)-were strongly linked to FMI. Diabetes (OR = 1.31, <i>p</i> = 0.003) and smoking (OR = 1.47, <i>p</i> < 0.0001) emerged as significant modifiable risks, while hypertension showed no association (<i>p</i> = 0.14). Age and gender disparities highlighted the need for personalized risk algorithms.</p><p><strong>Conclusion: </strong>Technological biomarkers and data-driven modeling provide actionable insights into FMI risk in SCAD, bridging gaps between anatomical assessments and functional outcomes. Future integration of machine learning and predictive analytics could refine risk stratification, enabling tailored therapeutic strategies.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"2164-2176"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Technology and Health Care
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