Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

{"title":"PET/TC en cáncer de mama","authors":"J.F. Bastidas ,&nbsp;M. Martínez de Bourio-Allona ,&nbsp;A. Roteta Unceta Barrenechea ,&nbsp;M. Rodríguez-Fraile ,&nbsp;L. Sancho","doi":"10.1016/j.remn.2025.500139","DOIUrl":"10.1016/j.remn.2025.500139","url":null,"abstract":"<div><div>Breast cancer is one of the most prevalent neoplasms worldwide, with molecular subtypes that influence prognosis and therapeutic strategies. PET/CT with different radiopharmaceuticals has revolutionized diagnosis, staging, and treatment monitoring. [¹⁸F]-Fluorodeoxyglucose remains the most widely used radiotracer, but it has limitations in certain subtypes, such as invasive lobular carcinoma, where 16α-[¹⁸F] fluoro-17β-estradiol and [⁶⁸Ga]-FAPI (fibroblast activation protein inhibitors) have demonstrated greater utility. Today, HER2-targeted radiopharmaceuticals, such as [⁸⁹Zr]-trastuzumab, allow for a precise assessment of tumor heterogeneity. PET/CT also plays a key role in detecting bone metastases using [¹⁸F]-NaF and in identifying new therapeutic targets, such as PSMA (prostate-specific membrane antigen) and GRPR (gastrin-releasing peptide receptor). These advancements establish molecular imaging as an essential tool for personalizing breast cancer treatment, optimizing clinical decision-making, and improving diagnostic accuracy.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 6","pages":"Article 500139"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145469026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SPECT/TC con 99mTc-sestamibi en el diagnóstico de masas renales","authors":"L. Pinilla,&nbsp;E. Riera,&nbsp;J.R. García,&nbsp;L. Mont-Castro,&nbsp;M. Soria,&nbsp;E. Valls","doi":"10.1016/j.remn.2025.500197","DOIUrl":"10.1016/j.remn.2025.500197","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 6","pages":"Article 500197"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"68Ga-FAPI y 18F-FDG PET/TC: modalidades de imagen complementarias para detectar metástasis inusuales en un paciente con osteosarcoma","authors":"G.A. Divband ,&nbsp;E. Askari ,&nbsp;H. Amini ,&nbsp;A. Noferesti ,&nbsp;P. Sahafi","doi":"10.1016/j.remn.2025.500137","DOIUrl":"10.1016/j.remn.2025.500137","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 6","pages":"Article 500137"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145469027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aportación del 123I en la estrumosis peritoneal","authors":"L. Delgado Niño ,&nbsp;J. Romero Martínez ,&nbsp;F. Martín Ordoñez","doi":"10.1016/j.remn.2025.500200","DOIUrl":"10.1016/j.remn.2025.500200","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 6","pages":"Article 500200"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Un año de contribuciones clave del Grupo de Trabajo de Oncología de la SEMNim","authors":"M. Rodríguez-Fraile","doi":"10.1016/j.remn.2025.500211","DOIUrl":"10.1016/j.remn.2025.500211","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 6","pages":"Article 500211"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linfoma B difuso de célula grande que simula enfermedad de Erdheim-Chester en la PET/TC con 18F-FDG","authors":"L. Yang ,&nbsp;P. Dong ,&nbsp;L. Li,&nbsp;M. Su","doi":"10.1016/j.remn.2025.500156","DOIUrl":"10.1016/j.remn.2025.500156","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 6","pages":"Article 500156"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifocal bone tuberculosis with adrenal involvement mimicking malignant tumors with multiple metastases on PET/CT","authors":"W. Zhang,&nbsp;Y. Xing,&nbsp;A. Kuang,&nbsp;Y. Li","doi":"10.1016/j.remn.2025.500141","DOIUrl":"10.1016/j.remn.2025.500141","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 6","pages":"Article 500141"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curso clínico y características del cáncer oncocítico de tiroides (células de Hürthle): comparación con el carcinoma folicular de tiroides","authors":"K. Okuyucu ,&nbsp;U.M. Turan ,&nbsp;P. Akkus Gunduz ,&nbsp;M. Ozkara ,&nbsp;N. Aydinbelge Dizdar ,&nbsp;A. Cinar ,&nbsp;M. Samsum ,&nbsp;P. Sahin Oguz ,&nbsp;R.D. Zeyrek ,&nbsp;N. Ersoz Gulcelik ,&nbsp;S. Ince","doi":"10.1016/j.remn.2025.500158","DOIUrl":"10.1016/j.remn.2025.500158","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Although oncocytic (Hurthle cell) carcinoma (OTC) resembles to follicular thyroid carcinoma (FTC), they are different tumours derived from thyroid follicular cells. OTC comprises 3-5% of all differentiated thyroid carcinomas and has more aggressive behaviour than FTC. Clinicians discuss about the treatment and prognosis of OTC. We evaluated its clinicopathological features and clinical course.</div></div><div><h3>Material and methods</h3><div>We examined and followed up 169 patients with OTC (126 minimally invasive, 43 widely invasive) and 837 patients with FTC (640 minimally invasive, 197 widely invasive). OTC and FTC were compared according to prognostic variables, recurrence rate (Rec) and outcome. The predictor factors impacting on recurrence in OTC were also determined.</div></div><div><h3>Results</h3><div>There were statistically significant differences between OTC and FTC in age, sex, capsule invasion (CI), tumor size (TS), total administered [¹³¹I]NaI dose (TID), stimulated thyroglobulin (sTg), Rec and stage (<em>P</em> <!-->&lt;<!--> <!-->.001, <em>P</em> <!-->=<!--> <!-->.032, <em>P</em> <!-->&lt;<!--> <!-->.001, <em>P</em> <!-->&lt;<!--> <!-->.001, <em>P</em> <!-->=<!--> <!-->.004, <em>P</em> <!-->=<!--> <!-->.026, <em>P</em> <!-->=<!--> <!-->.017, <em>P</em> <!-->=<!--> <!-->.044, respectively). Age, CI, extrathyroidal extension (ETE), TS, initial lymph node metastasis (ILNM), sTg and stage (<em>P</em> <!-->=<!--> <!-->.01, <em>P</em> <!-->=<!--> <!-->.016, <em>P</em> <!-->&lt;<!--> <!-->.001, <em>P</em> <!-->&lt;<!--> <!-->.001, <em>P</em> <!-->&lt;<!--> <!-->.001, <em>P</em> <!-->&lt;<!--> <!-->.001, <em>P</em> <!-->&lt;<!--> <!-->.001, respectively) were the predictors for recurrence in OTC. Metastasis incidence was 19.5% for OTC and 12% for FTC. The cause of death was cancer in 25 patients with FTC (2.8%) and 11 patients with OTC (6.5%).</div></div><div><h3>Conclusion</h3><div>The prognosis of minimally invasive OTC is quite favorable. However the prognosis of widely invasive OTC is unfavorable. RAI may be administered to these tumors, but it is in vain to insist on RAI after the first adjuvant therapy if it does not respond.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 6","pages":"Article 500158"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET/TC con 18F-colina en el estudio del hiperparatiroidismo primario: evaluación de la técnica, análisis visual y semicuantitativo y correlación con otras técnicas de imagen","authors":"E. Campaña Díaz ,&nbsp;F. Gómez-Caminero López ,&nbsp;J.M. Álvarez Pérez ,&nbsp;C. Montes Fuentes ,&nbsp;S. Rama Alonso ,&nbsp;J.Á. Badell Martínez ,&nbsp;P. García-Talavera San Miguel","doi":"10.1016/j.remn.2025.500129","DOIUrl":"10.1016/j.remn.2025.500129","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the usefulness of performing a dual-time-point protocol in the acquisition of ¹⁸F-Choline (¹⁸F-FCH) PET/CT in the pre-surgical localization of PHPT, and to demonstrate the impact of this imaging technique on the management and outcome-based surgical decision making, compared to other imaging techniques. To evaluate the diagnostic performance of the test to discriminate between pathological parathyroid gland and cervical lymph node, as well as to establish its correlation with other imaging techniques (scintigraphy, ultrasound, CT and MRI).</div></div><div><h3>Patients and methods</h3><div>We included 39 patients who underwent surgery for PHPT, in whom dual-time-point 18F-FCH PET/CT was performed. Metabolic index of parathyroid (P-SUVmax; P-SUVpeak), lymph node (N-SUVpeak), thyroid (T-SUVpeak) and mediastinum (M-SUVpeak) uptake were analyzed visually and semiquantitatively in both images. PET/CT results were correlated with ^99mTc-MIBI scintigraphy, ultrasound, MRI and CT.</div></div><div><h3>Results</h3><div>In 36 patients (92%), PET/CT was positive, localizing 38 pathological glands. The sensitivity (S) of PET/TC was 97% and positive predictive value (PPV) 94%. In the visual analysis, dual-time-point protocol was necessary in 61% of the cases. Correlation between PET/TC with MRI was 80%, with 4D-CT 50%, and with the other techniques &lt;<!--> <!-->50%. P-SUVmax shows correlation with adenoma weight and size, and with presurgical PTH. The best cutoff point for SUVpeak to differentiate parathyroid vs. lymph node was 2.6 in early images (S<!--> <!-->=<!--> <!-->70%; specificity<!--> <!-->=<!--> <!-->75%; <em>P</em>=.007) and 0.86 for SUVpeak/T-SUVpeak index (S<!--> <!-->=<!--> <!-->73%; specificity<!--> <!-->=<!--> <!-->69%; <em>P</em>=.001).</div></div><div><h3>Conclusion</h3><div>18F-FCH PET/CT is an excellent preoperative localization technique in patients with PHPT with negative, doubtful or inconclusive imaging techniques, being of vital importance in guiding minimally invasive surgery. The dual-time-point protocol was necessary in more than half of the cases (61%). The SUVpeak cut-off points to discriminate between parathyroid gland and lymph nodes were statistically significant.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 5","pages":"Article 500129"},"PeriodicalIF":1.6,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortitis micótica causada por BCG intravesical y cáncer de pulmón concomitante identificado mediante 18F-FDG PET/TC","authors":"K. Oksuzoglu,&nbsp;N. Zumbul","doi":"10.1016/j.remn.2025.500130","DOIUrl":"10.1016/j.remn.2025.500130","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 5","pages":"Article 500130"},"PeriodicalIF":1.6,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}