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Early Career Spotlight 早期职业聚焦
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3409110
Nancey Trevanian Tsai
For this issue, we feature Josh Niesen. He is 31/2 years into his position with Medtronic, after spending two summers as an intern during college. Josh earned the B.S. degree in biomedical engineering (BME) from the University of Wisconsin-Madison.
本期我们将介绍乔希-尼森(Josh Niesen)。他在大学期间曾有两个暑假在美敦力实习,现在已经在美敦力工作了 31 年半。乔希在威斯康星大学麦迪逊分校获得了生物医学工程(BME)学士学位。
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引用次数: 0
Challenges and Opportunities for Physiologically Controlled Therapy in Neural Systems 神经系统生理控制疗法的挑战与机遇
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405745
Victoria S. Marks, Rory J. Piper, Joram J. Van Rheede, Moaad Benjaber, Alexander L. Green, Martin T. Tisdall, Timothy J. Denison
Brain Stimulation Technology for the treatment of neurological disorders is rapidly evolving. With the advent of “bidirectional” systems, such as the Medtronic Percept, which are able to sense from and stimulate the brain simultaneously, there is opportunity to modify stimulation based on changes in brain activity. The utility of such a bidirectional application is exemplified by the success of the NeuroPace responsive neuro stimulation (RNS) device in the reduction of seizures [1] and pivotal trials of spinal cord stimulation for chronic leg pain using evoked compound action potentials to facilitate a homeostatic feedback system [2].
用于治疗神经系统疾病的脑刺激技术正在迅速发展。美敦力 Percept 等 "双向 "系统能够同时感知和刺激大脑,因此有机会根据大脑活动的变化改变刺激方式。NeuroPace 反应性神经刺激(RNS)设备在减少癫痫发作方面取得的成功[1],以及利用诱发复合动作电位促进平衡反馈系统对慢性腿痛进行脊髓刺激的关键试验[2],都证明了这种双向应用的实用性。
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引用次数: 0
From the Editor 编辑的话
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405688
Mike Hess
Fifty years ago, one of the most popular American television shows debuted this famous phrase: “We can rebuild him. We have the technology. We can make him better than he was. Better, stronger, faster.” Children and adults alike tuned in to see the latest adventures of Steve Austin, the Six Million Dollar Man, crime-fighting astronaut turned international spy who featured advanced implants that seamlessly blended cyberonic technology through neural interfaces to give him super speed, super strength, super vision, and more.
50 年前,美国最受欢迎的电视节目之一首次出现了这句名言:"我们可以重建他。我们拥有技术。我们可以让他变得比以前更好更好、更强、更快"儿童和成年人都在收看史蒂夫-奥斯汀的最新冒险故事。"六百万美元人"、打击犯罪的宇航员、国际间谍,这些先进的植入物通过神经接口无缝融合了网络技术,赋予了他超快的速度、超强的力量、超强的视力等等。
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引用次数: 0
Neuroengineering—Engineering the Nervous System 神经工程学--神经系统工程学
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405744
Bin He
Neuroengineering, also known as neural engineering, is a rapidly expanding interdisciplinary field that bridges neuroscience and engineering. It encompasses research at the cellular, tissue, and systems levels, and has become a core discipline within biomedical engineering and beyond. By applying engineering principles and methods, neuroengineering studies the nervous system and develops techniques for diagnosing, treating, and rehabilitating neurological disorders. This field includes neural sensing, signal processing, interfacing, modulation, computation, imaging, and device development, among others. Over the past decade, significant progress has been made in neuroengineering, or neurotechnology, which focuses more on neural devices or tools. This progress is partly attributable to initiatives such as the Brain Research through Advancing Innovative Neurotechnologies1 (BRAIN) Initiative in the U.S. and similar efforts worldwide.
神经工程,又称神经工程学,是一个迅速发展的跨学科领域,是神经科学与工程学的桥梁。它包括细胞、组织和系统层面的研究,已成为生物医学工程及其他领域的核心学科。通过应用工程原理和方法,神经工程学研究神经系统,并开发用于诊断、治疗和康复神经系统疾病的技术。这一领域包括神经传感、信号处理、接口、调制、计算、成像和设备开发等。过去十年来,神经工程或神经技术领域取得了重大进展,神经工程或神经技术更侧重于神经设备或工具。这一进展部分归功于美国的 "通过推动创新神经技术促进脑研究1 (BRAIN) 计划 "等倡议以及全球范围内的类似努力。
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引用次数: 0
Dismantling Descartes 拆解笛卡尔
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405748
Nancey Trevanian Tsai
In the 1999 movie The Matrix, Neo emerges from a vat of jelly shortly after taking the Red Pill. It suggested that there is a separation between the mind and the body and that the brain as the master driver of experiences could be hijacked to keep the body subjugated until its useful life—under the control of an outside force—had terminated. Likewise, students taking philosophy are often introduced to Rene Descartes’ “Cogito ergo sum,” which translates as, “I think, therefore I am.” The central idea of the discourse is that the mind is proof of existence, even if the body cannot be verified. Indeed, many of us seem to live one life inside our heads while our body moves through a different, physical world. By way of introducing the mind-body dichotomy, it also suggested an unintended hierarchy. Do any of us really believe we are mere “brain in a vat”?
在 1999 年的电影《黑客帝国》中,尼奥在服用 "红药丸 "后不久从一桶果冻中现身。这表明,精神和身体之间是分离的,大脑作为经验的主驱动力,可以被劫持,使身体受到奴役,直到其有用的生命在外力控制下终止。同样,学习哲学的学生经常会接触到笛卡尔的 "Cogito ergo sum",翻译过来就是 "我思故我在"。这段论述的中心思想是,即使身体无法验证,思想也是存在的证明。事实上,我们中的许多人似乎只在头脑中过着一种生活,而我们的身体却在另一个物理世界中穿梭。通过引入身心二分法,它还暗示了一种意想不到的等级制度。我们中真的有人相信自己只是 "缸中之脑 "吗?
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引用次数: 0
Mapping the Impossible: Europe’s Human Brain Project Comes of Age 绘制不可能的地图:欧洲的人脑项目进入成熟期
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405749
Jim Banks
Back in 2021, a paper recently published in The Lancet [1] defined the impact on human life of disorders affecting the nervous system. Neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment, were among 37 conditions reviewed. The results were chilling.
早在 2021 年,最近发表在《柳叶刀》上的一篇论文[1]就定义了影响神经系统的疾病对人类生活的影响。37种疾病中包括神经发育障碍、晚期神经变性和新出现的疾病,如认知障碍。结果令人不寒而栗。
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引用次数: 0
Innovations in Neurostimulation. 神经刺激的创新。
IF 0.3 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2024-05-01 DOI: 10.1109/MPULS.2024.3405746
Janet Rae-Dupree

While The Big medical device makers may have a deep-pockets advantage in the neurostimulation space, many smaller players are innovating their way to advances that offer tantalizing hope for changing patients' lives.

虽然大型医疗设备制造商可能在神经刺激领域拥有雄厚的资金优势,但许多小企业也在不断创新,为改变患者的生活带来了诱人的希望。
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引用次数: 0
Ultra-High to Ultra-Low: MRI Goes to Extremes. 从超高到超低:核磁共振成像达到极致。
IF 0.3 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2024-05-01 DOI: 10.1109/MPULS.2024.3405768
Leslie Mertz

Two of the hottest areas in magnetic resonance imaging (MRI) are at the extremes.

磁共振成像(MRI)最热门的两个领域都处于极端状态。
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引用次数: 0
Navigating Breast Cancer Innovation in Uganda: Within and Without the Textbook 乌干达乳腺癌创新之路:教科书之内与之外
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2024-04-15 DOI: 10.1109/mpuls.2024.3370450
Kim Hwang Yeo, Krishna Tejaswini Sathi, Soumyadipta Acharya, Youseph Yazdi
The Center for Bioengineering Innovation and Design (CBID) at Johns Hopkins University (JHU) has established a comprehensive approach to addressing global health challenges. Central to CBID’s modality on global health is a strategy that integrates education, research, and collaboration. Through its graduate program, CBID trains the next generation of health care innovators to address the specific needs of low- and middle-income countries (LMICs). Graduate student teams at CBID begin their year with a focus on a health care thematic area associated with a target country.
约翰霍普金斯大学(JHU)的生物工程创新与设计中心(CBID)已经建立了一套应对全球健康挑战的综合方法。CBID 全球健康模式的核心是整合教育、研究与合作的战略。CBID 通过其研究生项目培养下一代医疗创新人才,以满足中低收入国家(LMICs)的特殊需求。CBID 的研究生团队从一年级开始就专注于与目标国家相关的医疗保健主题领域。
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引用次数: 0
Taking Aim at Sepsis to Save Millions From Sudden Death 瞄准败血症,拯救数百万猝死者
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2024-04-15 DOI: 10.1109/mpuls.2024.3375688
Leslie Mertz
Sepsis is an urgent medical problem around the world with at least 47 million affected per year. Of those, about a quarter—at least 11 million—die, and many sepsis survivors face health repercussions for the rest of their lives, according to the Global Sepsis Alliance [1]. Along the same lines, the World Health Organization named sepsis as the cause of one in five deaths globally, and the U.S. Centers for Disease Control and Prevention (CDC) notes similiarly dire statistics [2]. These are some of many dire statistics that have prompted health agencies and biomedical innovators to address this massive health emergency.
败血症是全球亟待解决的医疗问题,每年至少有 4700 万人受到影响。根据全球败血症联盟(Global Sepsis Alliance)的数据[1],其中约四分之一(至少 1100 万人)死亡,许多败血症幸存者的余生都会受到健康影响。同样,世界卫生组织将败血症列为全球五分之一死亡的原因,美国疾病控制和预防中心(CDC)也指出了类似的可怕数据[2]。这些可怕的数据促使卫生机构和生物医学创新者着手应对这一巨大的健康紧急状况。
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引用次数: 0
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