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Artificial Intelligence Aided Ethics in Frontier Research. 人工智能辅助伦理前沿研究。
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-07-01 Epub Date: 2023-11-20 DOI: 10.1109/MPULS.2023.3324241
Andres Diaz Lantada, Mette Ebbesen

Emergent technologies are frequently demonized due to the fear of the unknown. The doubts and alarms are more often than not sparked by their own developers, in a secret wish to become the masters of such fears, and thereby increase their control and influence upon laymen. The story is as old as the use of fire by the sorcerers guiding most ancient rituals. Now it seems to be the turn of artificial intelligence (AI), which is being continuously tainted with quasi-apocalyptic shadows, despite its remarkable potentials for supporting highly desirable societal transformations.

由于对未知的恐惧,新兴技术经常被妖魔化。这些怀疑和警告往往是由他们自己的开发者引发的,他们暗地里希望成为这种恐惧的主人,从而增加他们对外行的控制和影响。这个故事和巫师使用火来指导最古老的仪式一样古老。现在似乎轮到人工智能(AI)了,尽管它在支持高度理想的社会变革方面具有巨大的潜力,但它仍不断受到准世界末日阴影的污染。
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引用次数: 0
Cover 2 封二
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-07-01 DOI: 10.1109/mpuls.2023.3328726
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引用次数: 0
Assessment of Fitness for Air travel in Patients with Pulmonary Diseases 肺部疾病患者适合乘飞机旅行的评估
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66892
S. Mamun, Ziaul Haque, R. Jahan, Sharif Md, Qazi Tariqul Islam
During air travel, increasing hypoxia with altitude ascent is a potentially serious problem for patients with hypoxemic chronic airway obstruction (CAO). Travel by air is the most popular way of transport nowadays & estimated that each year worldwide, more than 3 billion passengers travel by air & 736 million in the United States alone. For most passengers, even those with respiratory disease, air travel is safe and comfortable. Some patients with COPD &other Chronic Lung diseases may be at risk but, with screening, these patients can be identified and most of them can travel safely with supplemental oxygen. Some patients with chronic lung disease may have mild hypoxemia at sea level but during air travel in a hypobaric hypoxic environment, compensatory pulmonary mechanisms may be inadequate despite normal sea-level oxygen requirements. In addition, compensatory cardiovascular mechanisms may be less effective in some patients who are unable to increase cardiac output. Air travel also presents an increased risk of venous thromboembolism. It's estimated that, almost 1 medical emergency for every 600 flights. Respiratory symptoms accounted for 12% of all these in-air emergencies. Pulse Volume 12-14 2020-2022 p.16-21
在航空旅行中,低氧性慢性气道阻塞(CAO)患者随着海拔上升而增加的缺氧是一个潜在的严重问题。乘飞机旅行是当今最流行的交通方式&估计每年全球有超过30亿乘客乘飞机旅行&仅在美国就有7.36亿。对大多数乘客来说,即使是患有呼吸道疾病的乘客,空中旅行也是安全舒适的。一些患有慢性阻塞性肺病和其他慢性肺部疾病的患者可能存在风险,但通过筛查,这些患者可以被识别出来,并且大多数患者可以在补充氧气的情况下安全旅行。一些慢性肺病患者在海平面时可能出现轻度低氧血症,但在低气压低氧环境中进行航空旅行时,尽管正常的海平面需氧量,代偿性肺机制可能不足。此外,代偿性心血管机制在一些不能增加心输出量的患者中可能效果较差。航空旅行也会增加静脉血栓栓塞的风险。据估计,每600次飞行中几乎有一次医疗紧急情况。呼吸道症状占所有这些空中紧急情况的12%。脉冲体积12-14 2020-2022 p.16-21
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引用次数: 0
Dominance of human Influenza H1N1pdm09 in flu like patients during early two months of 2020 2020年前两个月流感样患者中人类流感H1N1pdm09的优势
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66831
R. Rahim, A. Hasan, Nazmul Hasan, N. Ara, S. Biswas, Mizanur Rahman
Introduction:Influenza is a worldwide respiratory infectious disease which affect all age groups and associated with significant number of morbidity and mortality each year. The circulating subtypes varies countrywide yearly, and it helps policy maker to get preparedness for early effective management of influenza epidemics. Materials and methods Nasal swabs were collected from 463 patients in January and February 2020 presenting flu-like symptoms and Rapid Influenza Diagnostics Tests (RIDTs) were performed for influenza A & B screening as a routine test. Then influenza A subtyping was done by RT-PCR followed by gel electrophoresis of 27 influenza positive samples. Result Among 463 cases, 106 (22.9%) were Influenza positive with huge (99.06%) dominance of Influenza A. Subtyping of randomly selected outpatient derived 27 Influenza A positive cases showed flourishing presence of seasonal Influenza A/H1N1pdm09 (21; 77.8%). Conclusion This small study warrants further elaborate investigation to know circulating influenza A subtyping in the country which may assist health care providers in making treatment decisions and hence, appropriate patient management. Pulse Volume 12-14 2020-2022 p.4-9
流感是一种世界性的呼吸道传染病,可影响所有年龄组,每年都有大量的发病率和死亡率。每年在全国范围内流行的亚型各不相同,这有助于决策者为早期有效管理流感流行做好准备。材料与方法收集2020年1月和2月出现流感样症状的463例患者的鼻拭子,并进行快速流感诊断测试(RIDTs)作为常规测试,筛查流感A和B。对27份流感阳性样本进行RT-PCR分型和凝胶电泳分析。结果在463例病例中,流感阳性106例(22.9%),其中甲型流感占绝大多数(99.06%)。随机抽取门诊甲型流感阳性病例27例,季节性流感A/H1N1pdm09 (21;77.8%)。结论:这项小型研究值得进一步详细调查,以了解该国流行的甲型流感亚型,这可能有助于卫生保健提供者做出治疗决定,从而进行适当的患者管理。脉冲体积12-14 2020-2022 p.4-9
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引用次数: 0
An interesting case of Posterior Layering in the Urinary bladder on Fluorine- 18 Fluorodeoxyglucose (F18-FDG) PET-CT study 氟- 18氟脱氧葡萄糖(F18-FDG) PET-CT研究膀胱后分层的有趣病例
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66895
S. Farhana, Taslima Sifat, Shohag Mia, R. Quddus, B. Khan, S. Islam, R. Hussain, MF Kabir
Contrast PET/CT may show layering within the UB, and several examples of have been reported in the literature. But without using contrast this is rare. Our case demonstrates the interesting posterior layering of F18-FDG in urinary bladder in a 78 years old male without the use of contrast. Pulse Volume 12-14 2020-2022 p.32-33
PET/CT造影剂可以显示UB内的分层,文献中也报道了几个这样的例子。但如果不使用对比,这是很罕见的。我们的病例在没有使用造影剂的情况下显示了78岁男性膀胱中F18-FDG的有趣后分层。脉冲体积12-14 2020-2022 p.32-33
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引用次数: 0
Pulse Official Vol.12-14 脉冲官方卷12-14
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66905
E. Chief
Abstract not available Pulse Volume 12-14 2020-2022 p.60-68
摘要不可用脉冲卷12-14 2020-2022页60-68
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引用次数: 0
Papillary Tumor of Pineal Region: A Case Report 松果体区乳头状肿瘤1例
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66834
A. Khaled, S. Alam
Pineal region tumors constitute about 0.4%-1% of intracranial tumors in adults. These tumors may arise from pineal gland itself or structures around it which are all termed as pineal region tumor. Papillary tumor of the pineal region is a non-parenchymal tumor of the pineal region. First described in 2003, it is an extremely rare tumor. We have presented a case of 27-year-old female patient presented as a pineal tumor. After successful excision, the tumor proved to be Papillary tumor of Pineal region (PTPR) both histomorphologically and immunohistochemical study. Pulse Volume 12-14 2020-2022 p.13-15
松果体区肿瘤约占成人颅内肿瘤的0.4%-1%。这些肿瘤可能起源于松果体本身或其周围的结构,这些结构都被称为松果体区肿瘤。松果体乳头状肿瘤是一种非实质肿瘤。这是一种极其罕见的肿瘤,于2003年首次被发现。我们报告了一位27岁的女性患者,表现为松果体肿瘤。成功切除后,经组织形态学和免疫组化研究证实为松果体区乳头状肿瘤(PTPR)。脉冲卷12-14 2020-2022 p.13-15
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引用次数: 0
Prevalence of Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, and Trichomonas vaginalis among patients suspected of sexually transmitted infections in Evercare Hospital Dhaka during 2015 to 2022 2015 - 2022年达卡Evercare医院疑似性传播感染患者淋病奈瑟菌、沙眼衣原体、生殖支原体和阴道毛滴虫的患病率
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66898
Nazmul Hasan, R. Rahim, A. Hasan, R. Ali, QM Mahbub Ullah, Mizanur Rahman
Background Sexually Transmitted Infections (STIs) are often diagnosed by clinical symptoms and signs due to lack of sensitive laboratory methods. Most of the time pathogens are not identified and antibiotics are used empirically. The purpose of our study is to find out the STI pathogens detected by sensitive multiplex PCR done routinely in a tertiary care hospital. Materials and methods A total of 578 samples were tested from February 2015 to July 2022. Urine, prostatic secretion, urethral swab, high vaginal swab, semen, throat swabs were collected from symptomatic patients for the routine test. DNA was extracted and Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis were screened by using CE-IVD approved multiplex Real Time PCR kit. Result Out of 578 cases, 76 (13.15%) were positive for at least one pathogen and 5 were co-infections. Out of 76 positive cases, Chlamydia trachomatis was found 41 (53.9%), Neisseria gonorrhoeae was 13 (17.1%), Mycoplasma genitalium was 12 (15.8%), and Trichomonas vaginalis 5 (6.6%) and co-infections with Neisseria gonorrhoeae and Chlamydia trachomatis was 5 (6.6%). Positivity rate was remarkably higher in male (77.6%) than female (22.4%) and predominant age group was 19-40 years. Conclusion The predominant STIs pathogen found in our cohort is Chlamydia trachomatis followed by Neisseria gonorrhoeae. Multiplex PCR is a wide-ranging diagnostic method for the detection of multiple pathogens simultaneously which allows early and accurate diagnosis of STIs. Pulse Volume 12-14 2020-2022 p.34-39
由于缺乏敏感的实验室方法,性传播感染(STIs)往往通过临床症状和体征进行诊断。大多数情况下,病原体无法识别,抗生素只能凭经验使用。本研究的目的是了解某三级医院常规多重PCR检测STI病原菌的情况。材料与方法2015年2月至2022年7月共检测样品578份。采集有症状患者的尿液、前列腺分泌物、尿道拭子、阴道高位拭子、精液、咽拭子进行常规检查。提取DNA,采用CE-IVD批准的多重实时荧光定量PCR试剂盒对淋病奈瑟菌、沙眼衣原体、生殖道支原体、阴道毛滴虫进行筛选。结果578例患者中,至少有一种病原菌阳性76例(13.15%),合并感染5例。76例阳性病例中,沙眼衣原体41例(53.9%),淋病奈瑟菌13例(17.1%),生殖道支原体12例(15.8%),阴道毛滴虫5例(6.6%),淋病奈瑟菌与沙眼衣原体共感染5例(6.6%)。男性阳性率(77.6%)明显高于女性(22.4%),主要年龄为19 ~ 40岁。结论以沙眼衣原体为主,其次为淋病奈瑟菌。多重PCR是一种广泛的诊断方法,可同时检测多种病原体,从而实现对性传播感染的早期和准确诊断。脉冲体积12-14 2020-2022 p.34-39
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引用次数: 0
Case series report of LINAC-based Stereotactic radiosurgery of Intracranial meningioma – an institutional experience 基于linac的立体定向放射治疗颅内脑膜瘤的病例系列报告——一种机构经验
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66900
T. Yasmin, Narendra Kumar, M. Appasamy, S. Ahsan, KM Masud Rana, R. Kumar, A. Joarder, Z. Rahman, B. Bhattacharjee, Taslima Afrin, Arman Reza Chowdhury
Stereotactic radiosurgery (SRS) has been widely used for the treatment of intracranial lesions. We have been doing SRS since March 2019. The unique ability of SRS to deliver higher focused dose to the smaller targets preferably in a single exposure in a convenient manner while sparing adjacent critical structures has made a more widely adopted treatment option. This case series is intended to show our institutional experience and procedural technique adapted for treating intracranial meningioma using SRS by Linear accelerators. We present five cases of intracranial meningioma. Four had Grade I meningioma and one patient with Grade III meningioma. One patient had radiological diagnosis only and treated with SRS. Two patients underwent gross total resection and SRS was prescribed on the event of recurrence. Rest two patients had recurrence/progression after subtotal resection and adjuvant radiation. The dose prescription ranged from 13 to 21Gy in one to three fractions which was determined by tumor volume, location, grade, proximity to critical structures, pre-existing neurologic impairment, previous treatment history, time to progression/relapse and the ideal balance of prescription dosage and expected problems. There were no acute side effects from any of the procedures. All five patients had improvement in clinical symptoms in the immediate post-SRS period. One patient who has two-year post-SRS revealed a significant regression in the size of the tumor. This case series summarizes the fact that SRS for intracranial meningioma is safe and effective treatment strategy when appropriate. Pulse Volume 12-14 2020-2022 p.40-52
立体定向放射外科(SRS)已广泛应用于颅内病变的治疗。我们从2019年3月开始做SRS。SRS的独特能力,最好是在单次照射中以方便的方式向较小的目标提供更高的聚焦剂量,同时不影响邻近的关键结构,这使其成为更广泛采用的治疗选择。本病例系列旨在展示我们的机构经验和适用于使用线性加速器的SRS治疗颅内脑膜瘤的程序技术。我们报告5例颅内脑膜瘤。4例为一级脑膜瘤,1例为三级脑膜瘤。1例患者仅行影像学诊断并接受SRS治疗。2例患者行大体全切除,复发时给予SRS治疗。其余2例患者在次全切除和辅助放疗后出现复发/进展。剂量处方由肿瘤体积、位置、分级、与关键结构的接近程度、既往神经功能损害、既往治疗史、进展/复发时间以及处方剂量与预期问题的理想平衡决定,剂量处方范围为13至21Gy,分为一至三部分。所有的手术都没有急性副作用。5例患者均在srs后立即出现临床症状改善。一名接受两年srs治疗的患者发现肿瘤大小明显缩小。本病例总结了SRS治疗颅内脑膜瘤在适当的情况下是安全有效的治疗策略。脉冲体积12-14 2020-2022 p.40-52
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引用次数: 0
Exosomes - A Potential Candidate to Combat Covid-19 and A Future Emerging Nanotechnology with Diverse Perspectives 外泌体-对抗Covid-19的潜在候选者和未来新兴纳米技术的不同视角
IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66893
Md Abu Quoreshi Khan
Corona virus causes severe contagious acute respiratory syndrome known as coronavirus disease 2019 (COVID-19). Several initiatives have been taken to tackle so far. One of them, being therapy based biological nano particles “Exosomes”. Administration of exosomes loaded with immunomodulatory cargo in combination with antiviral drugs will be a promising approach. This study deals with the exosomal isolation techniques of the Bruton Tyrosine Kinase (BTK) protein from cells. It represents initial trials to establish a method to isolate exosomes from human B cells. Pulse Volume 12-14 2020-2022 p.22-25
冠状病毒引起被称为2019冠状病毒病(COVID-19)的严重传染性急性呼吸系统综合征。到目前为止,已经采取了一些措施来解决这个问题。其中之一是基于治疗的生物纳米粒子“外泌体”。携带免疫调节货物的外泌体与抗病毒药物联合使用将是一种很有前途的方法。本研究涉及布鲁顿酪氨酸激酶(BTK)蛋白的细胞外泌体分离技术。这代表了建立从人B细胞中分离外泌体方法的初步试验。脉冲体积12-14 2020-2022 p.22-25
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引用次数: 0
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IEEE Pulse
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