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Pulse Official Vol.12-14 脉冲官方卷12-14
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66905
E. Chief
Abstract not available Pulse Volume 12-14 2020-2022 p.60-68
摘要不可用脉冲卷12-14 2020-2022页60-68
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引用次数: 0
An interesting case of Posterior Layering in the Urinary bladder on Fluorine- 18 Fluorodeoxyglucose (F18-FDG) PET-CT study 氟- 18氟脱氧葡萄糖(F18-FDG) PET-CT研究膀胱后分层的有趣病例
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66895
S. Farhana, Taslima Sifat, Shohag Mia, R. Quddus, B. Khan, S. Islam, R. Hussain, MF Kabir
Contrast PET/CT may show layering within the UB, and several examples of have been reported in the literature. But without using contrast this is rare. Our case demonstrates the interesting posterior layering of F18-FDG in urinary bladder in a 78 years old male without the use of contrast. Pulse Volume 12-14 2020-2022 p.32-33
PET/CT造影剂可以显示UB内的分层,文献中也报道了几个这样的例子。但如果不使用对比,这是很罕见的。我们的病例在没有使用造影剂的情况下显示了78岁男性膀胱中F18-FDG的有趣后分层。脉冲体积12-14 2020-2022 p.32-33
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引用次数: 0
Papillary Tumor of Pineal Region: A Case Report 松果体区乳头状肿瘤1例
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66834
A. Khaled, S. Alam
Pineal region tumors constitute about 0.4%-1% of intracranial tumors in adults. These tumors may arise from pineal gland itself or structures around it which are all termed as pineal region tumor. Papillary tumor of the pineal region is a non-parenchymal tumor of the pineal region. First described in 2003, it is an extremely rare tumor. We have presented a case of 27-year-old female patient presented as a pineal tumor. After successful excision, the tumor proved to be Papillary tumor of Pineal region (PTPR) both histomorphologically and immunohistochemical study. Pulse Volume 12-14 2020-2022 p.13-15
松果体区肿瘤约占成人颅内肿瘤的0.4%-1%。这些肿瘤可能起源于松果体本身或其周围的结构,这些结构都被称为松果体区肿瘤。松果体乳头状肿瘤是一种非实质肿瘤。这是一种极其罕见的肿瘤,于2003年首次被发现。我们报告了一位27岁的女性患者,表现为松果体肿瘤。成功切除后,经组织形态学和免疫组化研究证实为松果体区乳头状肿瘤(PTPR)。脉冲卷12-14 2020-2022 p.13-15
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引用次数: 0
Exosomes - A Potential Candidate to Combat Covid-19 and A Future Emerging Nanotechnology with Diverse Perspectives 外泌体-对抗Covid-19的潜在候选者和未来新兴纳米技术的不同视角
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66893
Md Abu Quoreshi Khan
Corona virus causes severe contagious acute respiratory syndrome known as coronavirus disease 2019 (COVID-19). Several initiatives have been taken to tackle so far. One of them, being therapy based biological nano particles “Exosomes”. Administration of exosomes loaded with immunomodulatory cargo in combination with antiviral drugs will be a promising approach. This study deals with the exosomal isolation techniques of the Bruton Tyrosine Kinase (BTK) protein from cells. It represents initial trials to establish a method to isolate exosomes from human B cells. Pulse Volume 12-14 2020-2022 p.22-25
冠状病毒引起被称为2019冠状病毒病(COVID-19)的严重传染性急性呼吸系统综合征。到目前为止,已经采取了一些措施来解决这个问题。其中之一是基于治疗的生物纳米粒子“外泌体”。携带免疫调节货物的外泌体与抗病毒药物联合使用将是一种很有前途的方法。本研究涉及布鲁顿酪氨酸激酶(BTK)蛋白的细胞外泌体分离技术。这代表了建立从人B细胞中分离外泌体方法的初步试验。脉冲体积12-14 2020-2022 p.22-25
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引用次数: 0
Prevalence of Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, and Trichomonas vaginalis among patients suspected of sexually transmitted infections in Evercare Hospital Dhaka during 2015 to 2022 2015 - 2022年达卡Evercare医院疑似性传播感染患者淋病奈瑟菌、沙眼衣原体、生殖支原体和阴道毛滴虫的患病率
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66898
Nazmul Hasan, R. Rahim, A. Hasan, R. Ali, QM Mahbub Ullah, Mizanur Rahman
Background Sexually Transmitted Infections (STIs) are often diagnosed by clinical symptoms and signs due to lack of sensitive laboratory methods. Most of the time pathogens are not identified and antibiotics are used empirically. The purpose of our study is to find out the STI pathogens detected by sensitive multiplex PCR done routinely in a tertiary care hospital. Materials and methods A total of 578 samples were tested from February 2015 to July 2022. Urine, prostatic secretion, urethral swab, high vaginal swab, semen, throat swabs were collected from symptomatic patients for the routine test. DNA was extracted and Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Trichomonas vaginalis were screened by using CE-IVD approved multiplex Real Time PCR kit. Result Out of 578 cases, 76 (13.15%) were positive for at least one pathogen and 5 were co-infections. Out of 76 positive cases, Chlamydia trachomatis was found 41 (53.9%), Neisseria gonorrhoeae was 13 (17.1%), Mycoplasma genitalium was 12 (15.8%), and Trichomonas vaginalis 5 (6.6%) and co-infections with Neisseria gonorrhoeae and Chlamydia trachomatis was 5 (6.6%). Positivity rate was remarkably higher in male (77.6%) than female (22.4%) and predominant age group was 19-40 years. Conclusion The predominant STIs pathogen found in our cohort is Chlamydia trachomatis followed by Neisseria gonorrhoeae. Multiplex PCR is a wide-ranging diagnostic method for the detection of multiple pathogens simultaneously which allows early and accurate diagnosis of STIs. Pulse Volume 12-14 2020-2022 p.34-39
由于缺乏敏感的实验室方法,性传播感染(STIs)往往通过临床症状和体征进行诊断。大多数情况下,病原体无法识别,抗生素只能凭经验使用。本研究的目的是了解某三级医院常规多重PCR检测STI病原菌的情况。材料与方法2015年2月至2022年7月共检测样品578份。采集有症状患者的尿液、前列腺分泌物、尿道拭子、阴道高位拭子、精液、咽拭子进行常规检查。提取DNA,采用CE-IVD批准的多重实时荧光定量PCR试剂盒对淋病奈瑟菌、沙眼衣原体、生殖道支原体、阴道毛滴虫进行筛选。结果578例患者中,至少有一种病原菌阳性76例(13.15%),合并感染5例。76例阳性病例中,沙眼衣原体41例(53.9%),淋病奈瑟菌13例(17.1%),生殖道支原体12例(15.8%),阴道毛滴虫5例(6.6%),淋病奈瑟菌与沙眼衣原体共感染5例(6.6%)。男性阳性率(77.6%)明显高于女性(22.4%),主要年龄为19 ~ 40岁。结论以沙眼衣原体为主,其次为淋病奈瑟菌。多重PCR是一种广泛的诊断方法,可同时检测多种病原体,从而实现对性传播感染的早期和准确诊断。脉冲体积12-14 2020-2022 p.34-39
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引用次数: 0
Case series report of LINAC-based Stereotactic radiosurgery of Intracranial meningioma – an institutional experience 基于linac的立体定向放射治疗颅内脑膜瘤的病例系列报告——一种机构经验
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66900
T. Yasmin, Narendra Kumar, M. Appasamy, S. Ahsan, KM Masud Rana, R. Kumar, A. Joarder, Z. Rahman, B. Bhattacharjee, Taslima Afrin, Arman Reza Chowdhury
Stereotactic radiosurgery (SRS) has been widely used for the treatment of intracranial lesions. We have been doing SRS since March 2019. The unique ability of SRS to deliver higher focused dose to the smaller targets preferably in a single exposure in a convenient manner while sparing adjacent critical structures has made a more widely adopted treatment option. This case series is intended to show our institutional experience and procedural technique adapted for treating intracranial meningioma using SRS by Linear accelerators. We present five cases of intracranial meningioma. Four had Grade I meningioma and one patient with Grade III meningioma. One patient had radiological diagnosis only and treated with SRS. Two patients underwent gross total resection and SRS was prescribed on the event of recurrence. Rest two patients had recurrence/progression after subtotal resection and adjuvant radiation. The dose prescription ranged from 13 to 21Gy in one to three fractions which was determined by tumor volume, location, grade, proximity to critical structures, pre-existing neurologic impairment, previous treatment history, time to progression/relapse and the ideal balance of prescription dosage and expected problems. There were no acute side effects from any of the procedures. All five patients had improvement in clinical symptoms in the immediate post-SRS period. One patient who has two-year post-SRS revealed a significant regression in the size of the tumor. This case series summarizes the fact that SRS for intracranial meningioma is safe and effective treatment strategy when appropriate. Pulse Volume 12-14 2020-2022 p.40-52
立体定向放射外科(SRS)已广泛应用于颅内病变的治疗。我们从2019年3月开始做SRS。SRS的独特能力,最好是在单次照射中以方便的方式向较小的目标提供更高的聚焦剂量,同时不影响邻近的关键结构,这使其成为更广泛采用的治疗选择。本病例系列旨在展示我们的机构经验和适用于使用线性加速器的SRS治疗颅内脑膜瘤的程序技术。我们报告5例颅内脑膜瘤。4例为一级脑膜瘤,1例为三级脑膜瘤。1例患者仅行影像学诊断并接受SRS治疗。2例患者行大体全切除,复发时给予SRS治疗。其余2例患者在次全切除和辅助放疗后出现复发/进展。剂量处方由肿瘤体积、位置、分级、与关键结构的接近程度、既往神经功能损害、既往治疗史、进展/复发时间以及处方剂量与预期问题的理想平衡决定,剂量处方范围为13至21Gy,分为一至三部分。所有的手术都没有急性副作用。5例患者均在srs后立即出现临床症状改善。一名接受两年srs治疗的患者发现肿瘤大小明显缩小。本病例总结了SRS治疗颅内脑膜瘤在适当的情况下是安全有效的治疗策略。脉冲体积12-14 2020-2022 p.40-52
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引用次数: 0
Is Helminthiasis a Precipitating Factor for Frequently Relapsing Nephrotic Syndrome? 蛔虫病是反复肾病综合征的诱发因素吗?
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66833
S. Sultana, M. Hanif, S. A. Luna
Nephrotic Syndrome (NS) is a common childhood illness. It is a disease of relapse and remission with major concern to manage the cases with relapse. Helminthiasis also a common problem in our subcontinent. So, it is very important to find out any relation with helminthiasis and relapse in children. In our study, 88 patients, clinically diagnosed as minimal change nephrotic syndrome, were studied to find out any relationship with helminthiasis and frequent relapse. 36 patients (40.9%) had no helminthic infection, 34 patients (38.6%) had helminthiasis and 18 patients (20.5%) had atopic disorders. 62 patients were successfully followed up for 6 months. Relapses occurred 47.8% (11/23) patients in non-helminthiasis group. 88.5% (23/26) in helminthiasis group and 84.6% (11/13) in atopic group, patients who completed follow up. Thirteen percent (3) patients in non-helminthiasis group, 50% (13) in helminthiasis group and 38.5% (5) in atopic group were found to be frequent relapser. The differences were statistically significant. Pulse Volume 12-14 2020-2022 p.10-12  
肾病综合征(NS)是一种常见的儿童疾病。它是一种复发和缓解的疾病,对复发病例的处理是主要关注的问题。蛔虫病也是我们次大陆的一个普遍问题。因此,了解儿童蛔虫病与复发的关系是十分重要的。在我们的研究中,我们研究了88例临床诊断为微小变化肾病综合征的患者,以寻找寄生虫病与频繁复发的关系。无寄生虫感染36例(40.9%),有寄生虫34例(38.6%),有特应性疾病18例(20.5%)。62例患者成功随访6个月。非蛔虫组复发率为47.8%(11/23)。蛔虫组88.5%(23/26),特应性组84.6%(11/13)完成随访。非蛔虫组有13%(3例)、蛔虫组有50%(13例)、特应性组有38.5%(5例)复发。差异有统计学意义。脉冲体积12-14 2020-2022 p.10-12
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引用次数: 0
Infective Endocarditis Associated with Multisystem Inflammatory Syndrome in Children (MIS-C): Two Case Studies 儿童感染性心内膜炎与多系统炎症综合征(MIS-C):两个案例研究
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66894
T. Nazrin, M. Hassan
Infective endocarditis (IE) is the infection of endocardial surface of the heart. IE is the rare disease with significant complications which require early diagnosis and proper treatment for reducing morbidity and mortality.IE with vegetation on pulmonary valve, leaflets are uncommon. However, we have diagnosed one case with infective endocarditis associated with Multisystem Inflammatory Syndrome in Children (MIS-C) which is related with COVID-19. MIS-C is commonly associated with coronary artery aneurysm (CAA), myocarditis and heart failure. Our patient had IE and was subsequently affected with MIS-C due to COVID. The child had vegetation on pulmonary valve with flail pulmonary valve-leaflet with grade II pulmonary regurgitation and MIS-C related CAA. The second child was previously diagnosed as infective endocarditis and was treated in other hospital for intravenous antibiotic for four weeks. However, in our hospital he was diagnosed clinically, by laboratory investigations and by echocardiography as MIS-C with large vegetation, which was surgically removed, and biopsy revealed mycobacterium tuberculosis as causative organism. Pulse Volume 12-14 2020-2022 p.26-31
感染性心内膜炎(IE)是指心脏的心内膜表面感染。IE是一种罕见的疾病,有明显的并发症,需要早期诊断和适当治疗,以降低发病率和死亡率。肺瓣上有植被的IE,小叶少见。然而,我们诊断出1例与COVID-19相关的儿童多系统炎症综合征(misc)相关的感染性心内膜炎。misc通常与冠状动脉瘤(CAA)、心肌炎和心力衰竭有关。我们的患者患有IE,随后因COVID而感染了misc。患儿肺动脉瓣赘生物伴连枷型肺动脉瓣-小叶伴II级肺返流及misc相关CAA。第二个孩子之前被诊断为感染性心内膜炎,在其他医院静脉注射抗生素治疗了四周。然而,在我们医院,通过临床、实验室检查和超声心动图诊断为misc伴大植被,手术切除,活检显示结核分枝杆菌为病原生物。脉冲卷12-14 2020-2022页26-31
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引用次数: 0
Patient safety culture plays an essential role to ensure safe patient care and quality in healthcare services 患者安全文化在确保患者安全护理和医疗保健服务质量方面发挥着至关重要的作用
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66902
Tahmina Rahman, Rezina Ahmed, A. Mahmud
Patient Safety is a global health priority. Every year, millions of patients suffer or die because of unsafe and poor- health care service. There are several factors which compromise patient safety and cause potential harm in health care settings. In developed countries, it is estimated that one in every 10 patients is harmed while receiving care in hospital. In developing countries, there is inadequate information on adverse event due to poor quality of health care service. Despite recent developments in Bangladesh, there is still great concern about the quality of care in healthcare sector. Evercare Hospital Dhaka is one of the leading private health care organizations in the country and committed towards patient safety from the very beginning. The purpose of this article is to discuss the importance of patient safety culture at healthcare service and how it is nurtured at Evercare hospital Dhaka by following the joint commission international standards. Pulse Volume 12-14 2020-2022 p.53-61
患者安全是一项全球卫生优先事项。每年,数以百万计的病人因不安全和糟糕的卫生保健服务而受苦或死亡。在卫生保健环境中,有几个因素会危及患者安全并造成潜在危害。在发达国家,估计每10名患者中就有1人在医院接受治疗时受到伤害。在发展中国家,由于卫生保健服务质量差,关于不良事件的信息不足。尽管孟加拉国最近取得了进展,但人们仍然非常关注保健部门的护理质量。达卡Evercare医院是该国领先的私营医疗机构之一,从一开始就致力于患者安全。本文的目的是讨论患者安全文化在医疗保健服务中的重要性,以及如何在Evercare医院遵循联合委员会国际标准来培养患者安全文化。脉冲体积12-14 2020-2022 p.53-61
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引用次数: 0
Antimicrobial Resistance and the next Pandemic 抗菌素耐药性和下一次大流行
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-06-14 DOI: 10.3329/pulse.v14i1-3.66830
Borhan Uddin Ahmed
Abstract not available Pulse Volume 12-14 2020-2022 p.3
摘要不可用脉冲卷12-14 2020-2022 p.3
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引用次数: 0
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