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The Challenge of Sepsis: Solving This Global Health Problem Requires Cross- Disciplinary Innovation 败血症的挑战:解决这一全球性健康问题需要跨学科创新
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2024-01-17 DOI: 10.1109/mpuls.2023.3344055
Leslie Mertz
Sepsis is one of the largest health crises of our time, and an ideal group to fight it are the innovators who comprise IEEE. That is the assessment of Timothy G. Buchman (Figure 1), Ph.D., M.D., an expert on the infection-triggered condition that each year claims the lives of more than 11 million people worldwide, including more than 350,000 [1] in the United States. “IEEE is a wonderful catalytic environment for biomedical specialists, engineers, computational scientists, epidemiologists—lots of people in different disciplines—to say, ‘What can we do today?’ The next breakthrough technology is already on somebody’s lab bench. It just hasn’t been connected to the problem,” he remarked.
败血症是我们这个时代最大的健康危机之一,而抗击这一危机的理想群体就是由 IEEE 组成的创新者。这是医学博士 Timothy G. Buchman(图 1)的评价,他是研究感染引发的败血症的专家,每年全球有 1100 多万人因此丧生,其中包括美国的 350,000 多人[1]。"IEEE为生物医学专家、工程师、计算科学家、流行病学家--许多不同学科的人--提供了一个绝佳的催化环境,让他们说:'我们今天能做些什么?'下一个突破性技术已经在某个人的实验室工作台上了。他说:"下一个突破性技术已经在某个实验室的工作台上了,只是还没有与问题联系起来。
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引用次数: 0
Harnessing Brain Stimulation to Enhance Memory 利用脑刺激增强记忆力
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2024-01-17 DOI: 10.1109/mpuls.2023.3344081
Summer Allen
Across the world, people are living longer. This phenomenon is creating a demographic shift: by 2050, the number of people aged 60 and older is expected to double and the number of people older than 80 is expected to triple [1]. A growing elderly population also means an increase in age-related health concerns. In particular, with age comes normal memory decline as well as an increased risk of Alzheimer’s and other dementias. All this means that now more than ever the world needs interventions to support memory. From developing memory protheses to improving memory consolidation during sleep, neurostimulation is one particularly promising type of intervention for enhancing memory.
在世界各地,人们的寿命越来越长。这一现象正在造成人口结构的转变:到 2050 年,60 岁及以上的人口预计将翻一番,80 岁以上的人口预计将增加两倍[1]。老年人口的增长也意味着与年龄相关的健康问题的增加。特别是,随着年龄的增长,记忆力会正常衰退,患老年痴呆症和其他痴呆症的风险也会增加。所有这些都意味着,现在世界比以往任何时候都更需要支持记忆的干预措施。从开发记忆保护器到改善睡眠中的记忆巩固,神经刺激是一种特别有前景的增强记忆干预方法。
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引用次数: 0
New Strategies for Addressing Antibiotic Resistance Offer Promise, but Time is Running Out 解决抗生素耐药性的新策略带来希望,但时间已经不多了
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-11-20 DOI: 10.1109/mpuls.2023.3324229
Leslie Mertz
As antibacterial resistance increases—now thought responsible for an estimated 5 million deaths worldwide each year [1] —scientists are investigating two distinct approaches to combating this deadly problem: Develop new antibiotics that defy pathogen resistance or design methods that hone antibiotic selection and fight individual infections better.
随着抗菌素耐药性的增加——现在被认为是全球每年约500万人死亡的原因[1]——科学家们正在研究两种截然不同的方法来解决这一致命问题:开发对抗病原体耐药性的新抗生素,或者设计优化抗生素选择并更好地对抗个体感染的方法。
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引用次数: 0
Digital Human Modeling and Medicine [Book review] 数字人体建模与医学[书评]
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-11-20 DOI: 10.1109/mpuls.2023.3324225
Paul H. King
This text, Digital Human Modeling and Medicine, is a comprehensive overview in 32 chapters distributed within six sections of the state-of-the-art and applications of the field of human modeling and applications in medicine. The 32 chapters were contributed by a total of about 89 contributors. The following topics are presented: modelling methods; organs; foot digital twin and in silico clinical applications; medical devices, and medical applications. Given the above range of topics, the text has an appeal to a wide range of relevant readers, from engineers to surgeons involved in interactions with the human body biomechanically or surgically. It is comprehensive, professionally written, referenced, and illustrated, and, through examples, of value to newcomers to the field.
这篇文章,数字人体建模和医学,是一个全面的概述,在32章的国家的最先进的和人体建模和医学应用领域的应用分布在六个部分。32章是由89位作者共同撰写的。提出以下主题:建模方法;器官;足部数字孪生体及计算机临床应用;医疗设备和医疗应用。鉴于上述主题范围,本文对广泛的相关读者具有吸引力,从工程师到参与与人体生物力学或外科相互作用的外科医生。它是全面的,专业的写作,参考和说明,并通过例子,价值的新手领域。
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引用次数: 0
Engineering Superiority 工程优势
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-11-20 DOI: 10.1109/mpuls.2023.3324224
Arthur T. Johnson
The Famous Engineer Henry Petroski once wrote about one of his students who asked, “Why do engineering students feel superior to those of us studying in nontechnical fields?” [2]. Petroski answered the question like this: “Engineers are recognized as the creative people who bring us innovations like the smart phone, the personal computer, the Internet, and the World Wide Web, all of which have revolutionized the way we live, work, and play.” He concluded that engineers are considered superior because of their knowledge and creativity. I’m not sure that he came to the correct conclusion.
著名工程师亨利·彼得斯基曾经写过他的一个学生问:“为什么工程专业的学生觉得比我们这些非技术专业的学生优越?””[2]。彼得罗夫斯基这样回答了这个问题:“工程师被认为是富有创造力的人,他们给我们带来了智能手机、个人电脑、互联网和万维网等创新,所有这些都彻底改变了我们的生活、工作和娱乐方式。”他的结论是,工程师被认为是优越的,因为他们的知识和创造力。我不敢肯定他是否得出了正确的结论。
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引用次数: 0
New Research Offers Clues About the Aging Brain 新的研究为大脑衰老提供了线索
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-11-20 DOI: 10.1109/mpuls.2023.3324228
Zara Abrams
Alzheimer’s disease (AD) is a grand challenge. It’s common, affecting about 10% of the population; it’s expensive, costing the nation nearly ${$}$ 350 billion in 2023; and it often causes years of suffering for patients and their loved ones [1]. Other age-related neurodegenerative conditions, such as vascular dementia and Parkinson’s disease, also continue to pose problems, both for patients and society as a whole.
阿尔茨海默病(AD)是一个巨大的挑战。它很常见,影响了大约10%的人口;这是昂贵的,到2023年,美国将花费近3500亿美元;它经常给病人和他们的亲人带来多年的痛苦[1]。其他与年龄有关的神经退行性疾病,如血管性痴呆和帕金森病,也继续给患者和整个社会带来问题。
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引用次数: 0
The Rising Threat of Antibiotic Resistance 不断上升的抗生素耐药性威胁
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-11-20 DOI: 10.1109/mpuls.2023.3324236
Leslie Mertz
We are Out of time. New, effective antibiotics are required to face the real and growing global threat from resistant and too often deadly bacterial infections. According to the World Health Organization, “Antibiotic resistance is rising to dangerously high levels in all parts of the world. New resistance mechanisms are emerging and spreading globally, threatening our ability to treat common infectious diseases.” The organization adds, “A growing list of infections, such as pneumonia, tuberculosis, blood poisoning, gonorrhea, and foodborne diseases, are becoming harder, and sometimes impossible, to treat as antibiotics become less effective” [1].
我们没时间了。需要新的、有效的抗生素来面对耐药性和往往致命的细菌感染带来的真正和日益严重的全球威胁。根据世界卫生组织的说法,“抗生素耐药性正在世界各地上升到危险的高水平。新的耐药机制正在出现并在全球蔓延,威胁到我们治疗常见传染病的能力。”该组织补充说:“随着抗生素的效果越来越差,越来越多的感染,如肺炎、肺结核、血液中毒、淋病和食源性疾病,正变得越来越难以治疗,有时甚至不可能治疗”[1]。
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引用次数: 0
To Sleep, Perchance to Dream. 沉睡,偶然入梦
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-11-01 DOI: 10.1109/MPULS.2024.3354568
Jim Banks

Most of us know the restorative value of an early night, so on some level we instinctively understand that sleep is good for both the body and the mind. Now, a growing body of research is starting to show just how vital sleep is to our overall health and longevity. Some believe that laughter is no longer the best medicine-sleep is.

我们大多数人都知道早睡早起的恢复价值,因此在某种程度上,我们本能地理解睡眠对身心都有好处。现在,越来越多的研究开始表明,睡眠对我们的整体健康和长寿有多么重要。有些人认为,欢笑不再是最好的良药,睡眠才是。
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引用次数: 0
Breakthroughs in Brain Implants. 大脑植入技术的突破。
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-11-01 DOI: 10.1109/MPULS.2024.3353668
Zara Abrams

In 2023, Brain implants got a big boost. Neuralink, Elon Musk's startup, began recruiting for its first clinical trial for paralysis patients; Precision Neuroscience received breakthrough designation from the Food and Drug Administration (FDA), allowing it to fast-track its own trials. Meanwhile, scientific advances are revealing promising new applications for such devices, including more comprehensive restoration of speech, sight, hearing, and movement to people who have lost those abilities, as well as help for psychiatric conditions, such as eating disorders and depression.

2023 年,大脑植入技术得到了极大的发展。埃隆-马斯克(Elon Musk)的初创公司神经链接(Neuralink)开始为其针对瘫痪病人的首次临床试验招募人员;精准神经科学公司(Precision Neuroscience)获得了美国食品和药物管理局(FDA)的突破性认证,从而可以快速开展自己的试验。与此同时,科学进步正在揭示这类设备大有可为的新应用,包括更全面地恢复失去语言、视觉、听觉和运动能力的人的能力,以及帮助治疗饮食失调和抑郁症等精神疾病。
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引用次数: 0
Novel Monitoring and Treatment Technologies for the Heart. 新型心脏监测和治疗技术。
IF 0.6 4区 医学 Q4 Engineering Pub Date : 2023-11-01 DOI: 10.1109/MPULS.2024.3354148
Leslie Mertz

Cardiovascular disease may be the world's leading killer of men and women, but new technologies are in development that could help lessen its impact. Among them are a variety of innovative external and internal patches that employ flexible and stretchable materials, machine learning, and other tactics to monitor heart activity and function, and in some cases to provide on-the-spot treatment.

心血管疾病可能是全球男性和女性的头号杀手,但正在开发的新技术可以帮助减轻心血管疾病的影响。其中包括各种创新的外部和内部贴片,它们采用柔性和可伸缩材料、机器学习和其他方法来监测心脏活动和功能,在某些情况下还能提供现场治疗。
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