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GLOW: Global Ophthalmic Women GLOW:全球眼科妇女。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-09-07 DOI: 10.1016/j.clae.2024.102302
Lakshmi Shinde
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引用次数: 0
Tear levels of Transforming Growth Factor-β1 and Interleukin 1-β, and clinical correlations in new contact lens users 隐形眼镜新使用者泪液中转化生长因子-β1 和白细胞介素 1-β 的水平及临床相关性。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-09-04 DOI: 10.1016/j.clae.2024.102299
Eduardo Insua Pereira , Ana Paula Sampaio , Madalena Lira

Purpose

To assess alterations in the tear Transforming Growth Factor (TGF)-β1 and Interleukin (IL1)-β concentration in new contact lens wearers; and explore correlations with tear film stability, and ocular physiological response.

Methods

In this clinical setting, 12 neophytes (5 males), with an average age of 24.0 ± 5.0 years were fitted with delefilcon A contact lenses. Physiological responses (bulbar and limbal hyperemia), Pre-corneal (NIBUT), Pre-lens (PL-NIBUT) non-Invasive Break-Up Times, and tear samples were collected in the morning (before lens insertion; 9 – 10 a.m.) and afternoon (before lens removal; 7 – 8p.m.) of the same day. NIBUT and PL-NIBUT were measured using a tearscope. Tear samples were assayed for TGF-β1 and IL1-β concentrations using Enzyme-Linked Immunosorbent Assay kits. An 11-members control group (6 males) aged 25.0 ± 5.0, served to assess biomarker levels in non-contact lens wearers’ tears.

Results

Subjects wore lenses for an average of 7 h and 20 min (range: 6 to 9 h). Bulbar and limbal hyperemia increased significantly throughout the day (p < 0.001). PL-NIBUT were lower than NIBUT (4.7 ± 2.0 Vs. 12.2 ± 8.8 s; p < 0.001). The IL1-β levels were higher in neophytes than controls (3.2 ± 4.7 Vs. 0.1 ± 0.1 pg/ml; p = 0.05), correlating significantly with bulbar (r = 0.405, p = 0.008) and limbal hyperemia (r = 0.499, p = 0.027). No substantial changes were reported for TGF-β1.

Conclusion

The presence of TGF-β1 in tears does not appear significantly affected by lens wear. The association between physiological parameters and IL1-β levels suggests that lenses may disrupt ocular surface homeostasis by altering cytokine regulatory mechanisms. However, due to its low concentration, IL1-β’s role in the subclinical inflammatory response to lens wear is limited.
目的:评估隐形眼镜新配戴者泪液中转化生长因子(TGF)-β1 和白细胞介素(IL1)-β 浓度的变化,并探讨其与泪膜稳定性和眼部生理反应的相关性:在临床环境中,为 12 名新手(5 名男性)配戴了 delefilcon A 型隐形眼镜,他们的平均年龄为 24.0 ± 5.0 岁。在当天上午(镜片插入前,上午 9 - 10 点)和下午(镜片摘除前,晚上 7 - 8 点)收集生理反应(球结膜和角结膜充血)、角膜前(NIBUT)、镜片前(PL-NIBUT)非侵入性破裂时间和泪液样本。使用泪液镜测量 NIBUT 和 PL-NIBUT。使用酶联免疫吸附试剂盒检测泪液样本中 TGF-β1 和 IL1-β 的浓度。对照组有 11 名成员(6 名男性),年龄为 25.0 ± 5.0,用于评估非隐形眼镜佩戴者泪液中的生物标志物水平:受试者佩戴镜片的平均时间为 7 小时 20 分钟(范围:6 至 9 小时)。球结膜和角结膜充血在一天中明显增加(P泪液中 TGF-β1 的存在似乎不会受到佩戴镜片的明显影响。生理参数与 IL1-β 水平之间的关联表明,镜片可能会通过改变细胞因子调节机制来破坏眼表平衡。然而,由于其浓度较低,IL1-β 在镜片佩戴引起的亚临床炎症反应中的作用有限。
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引用次数: 0
Changes in anterior segment after short-term scleral lens wear in healthy Chinese population. 中国健康人群短期佩戴巩膜透镜后眼前节的变化。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-09-03 DOI: 10.1016/j.clae.2024.102291
Qianni Jiang, Zhe Zhang, Lingling Niu, Bingjie Wang, Daddi Fadel, Ruihua Wei, Zhi Chen

Purpose: To evaluate the impact of short-term scleral lens (SL) wear on anterior chamber (AC) dimension and central corneal thickness (CCT) in healthy Chinese people.

Methods: This is a prospective, daily wear study. Eligible participants were dispensed SLs to correct refractive errors. Anterior segment (AS) parameters were measured by AS optical coherence tomography (AS-OCT) before, during, and after 2 and 4 hours of lens wear. Repeated-measures analysis of variance (ANOVA) was used to analyze the changes in AS parameters over time.

Results: Twelve subjects (10 females and 2 males) with a mean age of 25.3 ± 3.8 years (ranging from 21 to 34 years) were recruited. The AC parameters, including anterior chamber depth (ACD) from the endothelium (endo-ACD), angle opening distance at 500 μm (AOD500), and trabecular-iris space area at 500 μm (TISA500), significantly decreased after wearing SLs for 4 hours (P<0.05). CCT increased by 12 μm (2.29 %) after wearing SLs for 4 hours (P=0.013).

Conclusion: This study suggests that SL wear has a significant impact on AS dimensions in patients with healthy corneas in the short term with SL in situ, but tend to recover quickly after SL removal. Further research is needed to determine whether the change in AS dimensions during SL wear affects aqueous humor (AH) outflow and causes changes in intraocular pressure (IOP).

目的:评估健康中国人短期佩戴巩膜透镜(SL)对前房(AC)尺寸和中央角膜厚度(CCT)的影响:这是一项前瞻性日常配戴研究。方法:这是一项前瞻性的每日配戴研究,符合条件的参与者配戴睫状体镜片来矫正屈光不正。在戴镜前、戴镜期间以及戴镜 2 小时和 4 小时后,通过 AS 光学相干断层扫描(AS-OCT)测量前段(AS)参数。采用重复测量方差分析(ANOVA)分析AS参数随时间的变化:共招募了 12 名受试者(10 名女性和 2 名男性),平均年龄为 25.3 ± 3.8 岁(21 至 34 岁不等)。结果:12 名受试者(10 名女性和 2 名男性,平均年龄为 25.3 ± 3.8 岁,从 21 岁到 34 岁不等)在佩戴 SL 4 小时后,AC 参数,包括前房距内皮深度(ACD)(endo-ACD)、500 μm 时的开角距离(AOD500)和 500 μm 时的小梁-虹膜间隙面积(TISA500)显著下降(PConclusion:这项研究表明,在原位佩戴角膜塑形镜的情况下,短期内佩戴角膜塑形镜会对健康角膜患者的AS尺寸产生重大影响,但在摘除角膜塑形镜后会迅速恢复。还需要进一步研究,以确定在佩戴角膜塑形镜期间,角膜塑形镜尺寸的变化是否会影响房水(AH)的流出并导致眼压(IOP)的变化。
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引用次数: 0
Prospective registry-based external validation cohort analysis of dry eye disease subtype classification criteria 干眼症亚型分类标准的前瞻性登记外部验证队列分析。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-09-03 DOI: 10.1016/j.clae.2024.102290
Michael T.M. Wang , Jennifer P. Craig , Barry Power , James S. Wolffsohn
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引用次数: 0
The effect of extended periods of mini-scleral lens wear on the conjunctival/episcleral and scleral thickness. 长时间佩戴微型巩膜透镜对结膜/巩膜外膜和巩膜厚度的影响。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-30 DOI: 10.1016/j.clae.2024.102289
Ruveyde Bolac, Merve Beyza Yıldız, Oksan Alpogan, Yasemin Un, Mehmet Serhat Mangan

Purpose: To evaluate the conjunctival/episcleral thickness (CET) and anterior scleral thickness (AST) in patients with keratoconus with an extended duration of mini-scleral contact lens wear by utilizing anterior segment optical coherence tomography (ASOCT).

Methods: This study included 17 eyes of 17 patients with keratoconus with mini-scleral contact lens wear (Group 1), 20 eyes of 20 patients with keratoconus without any contact lens wear (Group 2), and 20 eyes of 20 healthy controls (Group 3). CET and AST were measured using AS-OCT (Triton, Topcon, Japan) at 1, 2, and 3 mm posterior to the scleral spur in the nasal, temporal, superior, and inferior quadrants.

Results: The median age of the mini-scleral contact lens group was 26, and the number of male patients was 14 (82.4 %). The superior CET values at 1 mm, 2 mm, and 3 mm statistically differed between the groups, with Group 1 having significantly lower values than Group 3 and Group 2 having statistically similar values to the remaining two groups. The inferior CET at 2 mm was lower in Groups 1 and 2 than in Group 3. The inferior CET at 3 mm was lower in Group 1 compared to Groups 2 and 3. AST was similar between the groups at all measured quadrants and distances. The duration of lens wear had a strong, statistically significant, negative correlation with the superior CET at 2 mm (rho: -0.847, p < 0.001) and a moderate, statistically significant, negative correlation with the superior CET at 3 mm (rho: -0.506, p < 0.038).

Conclusions: In this study, it was found that mini-scleral contact lens usage causes thinning in the conjunctival-episcleral layer, especially in the superior and inferior quadrants, but does not affect scleral thickness. AS-OCT is a non-invasive and clinically applicable technique for assessing the impact of contact lens use on the conjunctiva/episclera and sclera.

目的:利用前节光学相干断层扫描(ASOCT)评估长期佩戴微型巩膜接触镜的角膜病患者的结膜/巩膜外膜厚度(CET)和前巩膜厚度(AST):本研究包括 17 名佩戴微型巩膜接触镜的角膜病患者的 17 只眼睛(第 1 组)、20 名未佩戴任何接触镜的角膜病患者的 20 只眼睛(第 2 组)和 20 名健康对照者的 20 只眼睛(第 3 组)。使用 AS-OCT(Triton,日本拓普康公司)在鼻、颞、上和下象限巩膜骨刺后 1、2 和 3 毫米处测量 CET 和 AST:迷你巩膜接触镜组的中位年龄为 26 岁,男性患者为 14 人(82.4%)。各组在 1 毫米、2 毫米和 3 毫米处的上部 CET 值在统计学上存在差异,第一组的值明显低于第三组,而第二组的值在统计学上与其余两组相似。第 1 组和第 2 组 2 毫米处的下部 CET 低于第 3 组,第 1 组 3 毫米处的下部 CET 低于第 2 组和第 3 组。在所有测量的象限和距离上,各组之间的 AST 相似。镜片配戴时间与 2 毫米处的上部 CET 呈显著负相关(rho:-0.847,p 结论:本研究发现,佩戴微型巩膜接触镜会导致结膜-巩膜外层变薄,尤其是在上象限和下象限,但不会影响巩膜厚度。AS-OCT 是一种非侵入性且适用于临床的技术,可用于评估使用隐形眼镜对结膜/巩膜和巩膜的影响。
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引用次数: 0
Artificial intelligence in corneal diseases: A narrative review 人工智能在角膜疾病中的应用:综述。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-27 DOI: 10.1016/j.clae.2024.102284
Tuan Nguyen , Joshua Ong , Mouayad Masalkhi , Ethan Waisberg , Nasif Zaman , Prithul Sarker , Sarah Aman , Haotian Lin , Mingjie Luo , Renato Ambrosio , Aydano P. Machado , Darren S.J. Ting , Jodhbir S. Mehta , Alireza Tavakkoli , Andrew G. Lee
Corneal diseases represent a growing public health burden, especially in resource-limited settings lacking access to specialized eye care. Artificial intelligence (AI) offers promising solutions for automating the diagnosis and management of corneal conditions. This narrative review examines the application of AI in corneal diseases, focusing on keratoconus, infectious keratitis, pterygium, dry eye disease, Fuchs endothelial corneal dystrophy, and corneal transplantation. AI models integrating diverse imaging modalities (e.g., corneal topography, slit-lamp, and anterior segment OCT images) and clinical data have demonstrated high diagnostic accuracy, often outperforming human experts. Emerging trends include the incorporation of biomechanical data to enhance keratoconus detection, leveraging in vivo confocal microscopy for diagnosing infectious keratitis, and employing multimodal approaches for comprehensive disease analysis. Additionally, AI has shown potential in predicting disease progression, treatment outcomes, and postoperative complications in corneal transplantation. While challenges remain such as population heterogeneity, limited external validation, and the “black box” nature of some models, ongoing advancement in explainable AI, data augmentation, and improved regulatory frameworks can serve to address these limitations.
角膜疾病是一个日益沉重的公共卫生负担,尤其是在资源有限、缺乏专业眼科护理的环境中。人工智能(AI)为角膜疾病的自动化诊断和管理提供了前景广阔的解决方案。这篇叙述性综述探讨了人工智能在角膜疾病中的应用,重点关注角膜炎、感染性角膜炎、翼状胬肉、干眼症、富克斯内皮角膜营养不良症和角膜移植。集成了多种成像模式(如角膜地形图、裂隙灯和前段 OCT 图像)和临床数据的人工智能模型已证明诊断准确性很高,往往优于人类专家。新出现的趋势包括结合生物力学数据加强角膜病检测、利用体内共焦显微镜诊断感染性角膜炎,以及采用多模态方法进行综合疾病分析。此外,人工智能在预测角膜移植的疾病进展、治疗效果和术后并发症方面也显示出潜力。虽然仍存在人口异质性、有限的外部验证和某些模型的 "黑箱 "性质等挑战,但可解释的人工智能、数据扩增和改进的监管框架的不断进步可有助于解决这些局限性。
{"title":"Artificial intelligence in corneal diseases: A narrative review","authors":"Tuan Nguyen ,&nbsp;Joshua Ong ,&nbsp;Mouayad Masalkhi ,&nbsp;Ethan Waisberg ,&nbsp;Nasif Zaman ,&nbsp;Prithul Sarker ,&nbsp;Sarah Aman ,&nbsp;Haotian Lin ,&nbsp;Mingjie Luo ,&nbsp;Renato Ambrosio ,&nbsp;Aydano P. Machado ,&nbsp;Darren S.J. Ting ,&nbsp;Jodhbir S. Mehta ,&nbsp;Alireza Tavakkoli ,&nbsp;Andrew G. Lee","doi":"10.1016/j.clae.2024.102284","DOIUrl":"10.1016/j.clae.2024.102284","url":null,"abstract":"<div><div>Corneal diseases represent a growing public health burden, especially in resource-limited settings lacking access to specialized eye care. Artificial intelligence (AI) offers promising solutions for automating the diagnosis and management of corneal conditions. This narrative review examines the application of AI in corneal diseases, focusing on keratoconus, infectious keratitis, pterygium, dry eye disease, Fuchs endothelial corneal dystrophy, and corneal transplantation. AI models integrating diverse imaging modalities (e.g., corneal topography, slit-lamp, and anterior segment OCT images) and clinical data have demonstrated high diagnostic accuracy, often outperforming human experts. Emerging trends include the incorporation of biomechanical data to enhance keratoconus detection, leveraging in vivo confocal microscopy for diagnosing infectious keratitis, and employing multimodal approaches for comprehensive disease analysis. Additionally, AI has shown potential in predicting disease progression, treatment outcomes, and postoperative complications in corneal transplantation. While challenges remain such as population heterogeneity, limited external validation, and the “black box” nature of some models, ongoing advancement in explainable AI, data augmentation, and improved regulatory frameworks can serve to address these limitations.</div></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"47 6","pages":"Article 102284"},"PeriodicalIF":4.1,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142094093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between vision-related quality of life and mental health status in myopia children using various optical correction aids 使用各种光学矫正辅助设备的近视儿童视力相关生活质量与心理健康状况之间的关系。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-26 DOI: 10.1016/j.clae.2024.102287
Wen Zhang , Shuai Chang , Jinyun Jiang, Mengting Yu, Shuoshuo Chen, Yin Hu, Zhouyue Li, Xiao Yang

Purpose

To evaluate the relationship between vision-related quality of life and mental health in myopia children with various optical aids.

Methods

This cross-sectional study enrolled children aged 8–13 years, exhibiting myopia ranging from −4.50 to −0.75 D, and utilizing various optical aids for correction. Full ocular examinations and completion of two questionnaires were performed. Vision-related quality of life was evaluated using the Paediatric Refractive Error Profile (PREP), and mental health status was assessed utilising the Screen for Child Anxiety Related Emotional Disorders (SCARED). Univariate and multivariate analyses were conducted to evaluate the association between vision-related quality of life and mental health status.

Results

The study sample comprised 209 children with corrected myopia using single vision spectacles (100 [47.8 %]), soft contact lenses (66 [31.6 %]), and orthokeratology lenses (43 [20.6 %]). The mean age was 10.31 ± 1.65 y, and males accounted for 50.7 % of the sample. The distribution of demographic characteristics showed no significant difference among all correction types, except that the myopia duration was longer for orthokeratology lens wearers than those using spectacles (P=0.03). Contact lens showed clear benefits in almost all dimensions of vision-related quality of life, especially in appearance, satisfaction, activity and peer perceptions dimensions. The prevalence of anxiety disorders among spectacle wearers was 25.0 %, the highest among all groups. For myopia children with optical corrections, not being in the top 30 percent of their class rank, reporting lower PREP scores on symptoms, handling and peer perceptions dimensions were related with a higher prevalence of anxiety disorders.

Conclusions

Lower vision-related quality of life was associated with worse mental health status of myopia children with optical corrections. Identifying this association is crucial for protecting the mental health of myopia children and enhancing corrective measures.

目的:评估使用各种光学辅助设备的近视儿童与视力相关的生活质量和心理健康之间的关系:这项横断面研究招募了 8-13 岁的儿童,他们的近视度数在 -4.50 到 -0.75 D 之间,并使用各种光学辅助设备进行矫正。他们接受了全面的眼部检查,并填写了两份问卷。与视力相关的生活质量通过儿童屈光不正档案(PREP)进行评估,心理健康状况通过儿童焦虑相关情绪障碍筛查(SCARED)进行评估。对视力相关生活质量与心理健康状况之间的关系进行了单变量和多变量分析:研究样本包括 209 名使用单光眼镜(100 [47.8%])、软性隐形眼镜(66 [31.6%])和角膜塑形镜(43 [20.6%])矫正近视的儿童。样本的平均年龄为 10.31 ± 1.65 岁,男性占 50.7%。人口统计学特征的分布显示,所有矫正类型之间没有明显差异,只是角膜塑形镜佩戴者的近视持续时间比使用眼镜者更长(P=0.03)。隐形眼镜在几乎所有与视力相关的生活质量方面都有明显优势,尤其是在外观、满意度、活动和同伴感知方面。配戴眼镜者的焦虑症发病率为 25.0%,是所有群体中最高的。对于接受光学矫正的近视儿童来说,如果在班级排名中不是前 30%,在症状、处理和同伴感知方面的 PREP 分数较低,则焦虑症的发病率较高:结论:视力相关生活质量较低与接受光学矫正的近视儿童心理健康状况较差有关。发现这种关联对于保护近视儿童的心理健康和加强矫正措施至关重要。
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引用次数: 0
Comparison of susceptibility of Pseudomonas aeruginosa isolated from keratitis to antibiotics and multipurpose disinfecting solutions 比较从角膜炎中分离出来的铜绿假单胞菌对抗生素和多用途消毒液的敏感性。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-22 DOI: 10.1016/j.clae.2024.102288
Motohiro Itoi , Mark D.P. Willcox

Purpose

This study aimed to assess the susceptibility of ocular isolates of Pseudomonas aeruginosa to two multi-purpose disinfectant solutions (MPDS) and to determine if there was a relationship with resistance to antibiotics.

Methods

Twenty-three strains of P. aeruginosa isolated from microbial keratitis cases in Australia were utilized in this study. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of two commercially available MPDSs, Biotrue and cleadew MPS were determined. Additionally, the MIC of the strains to five antibiotics, ciprofloxacin, levofloxacin, gentamicin, ceftazidime, and imipenem, were analyzed.

Results

All strains were susceptible to 100 % of each of the MPDS. However, when MPDSs were diluted, cleadew MPS had significantly lower median MIC (median = 12.5 vs 25; p = 0.00008) and MBC (median = 25 vs 50; p = 0.0027) compared to Biotrue. All tested strains were susceptible to levofloxacin and gentamicin. Susceptibility rates to ciprofloxacin, imipenem, and ceftazidime were 52.2 %, 30.4 %, and 91.3 %, respectively. There were no significant relations between MIC or MBC to either MPDS and resistance to the antibiotics (p≧0.23).

Conclusion

Both MPDSs were active against P. aeruginosa isolated from microbial keratitis in Australia. However, after dilution, cleadew MPS remained active against P. aeruginosa at lower concentrations. Certain strains of P. aeruginosa were resistant to imipenem, ceftazidime or ciprofloxacin. The lack of association of susceptibility to MPDS and antibiotics suggest that resistance to one did not predispose to resistance to the other.
目的:本研究旨在评估眼部铜绿假单胞菌分离株对两种多用途消毒剂溶液(MPDS)的敏感性,并确定其是否与抗生素耐药性有关:本研究采用了从澳大利亚微生物角膜炎病例中分离出的 23 株铜绿假单胞菌。测定了两种市售 MPDS(Biotrue 和 cleadew MPS)的最低抑菌浓度 (MIC) 和最低杀菌浓度 (MBC)。此外,还分析了菌株对环丙沙星、左氧氟沙星、庆大霉素、头孢他啶和亚胺培南这五种抗生素的 MIC:结果:所有菌株对每种 MPDS 的敏感率均为 100%。然而,当稀释 MPDS 时,与 Biotrue 相比,cleadew MPS 的 MIC 中位数(中位数 = 12.5 vs 25;p = 0.00008)和 MBC 中位数(中位数 = 25 vs 50;p = 0.0027)明显较低。所有测试菌株都对左氧氟沙星和庆大霉素敏感。对环丙沙星、亚胺培南和头孢他啶的敏感率分别为 52.2%、30.4% 和 91.3%。两种多肽释放抑制剂的 MIC 或 MBC 与抗生素耐药性之间无明显关系(p≧0.23):结论:两种 MPDS 对从澳大利亚微生物性角膜炎中分离出的铜绿假单胞菌都有活性。然而,稀释后,在较低浓度下,洁霉素 MPS 对铜绿假单胞菌仍有活性。某些铜绿假单胞菌菌株对亚胺培南、头孢他啶或环丙沙星具有抗药性。对 MPDS 和抗生素的敏感性没有关联,这表明对其中一种抗生素的耐药性不会导致对另一种抗生素的耐药性。
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引用次数: 0
Shared decision‐making, treatment decision regret, and vision-related quality of life among parents of children with myopia: An online survey in Taiwan 近视儿童家长的共同决策、治疗决策后悔以及与视力相关的生活质量:台湾在线调查。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-06 DOI: 10.1016/j.clae.2024.102283
Li-Chun Chang , Chi-Chin Sun , Tzu-Chi Lee , Ya-Ni Wang , Li-Ling Liao

Objectives

To investigate the relationships among myopia treatment, decision regret, shared decision-making, and vision-related quality of life among parents of 6–12-year-old children with myopia.

Methods

An online Google Forms questionnaire was developed using a cross-sectional design and distributed between January 16 and August 22, 2023. Parents of 6–12-year-old children with myopia were recruited through school nurses working in Taiwan. The children’s and parents’ demographic data were collected. Study instruments included the Decisional Regret Scale, Shared Decision‐Making, and Vision-Related Quality of Life questionnaires. Multivariable linear regression analysis was used to identify factors influencing vision-related quality of life.

Results

Of 350 parents contacted, 314 questionnaires were analyzed. Among the respondents, 77.39 % (n = 243) were mothers, and most were aged >40 years. The mean age of children at myopia diagnosis was 7.12 ± 1.24 years; 46.50 % had < − 1.0 diopters of refractive error. Atropine eye drops were the primary treatment; 17.71 % of children were prescribed orthokeratology for myopia control. Parents reported low levels of decision regret and moderate levels of shared decision-making and vision-related quality of life. Children’s age, use of orthokeratology lenses, decision regret, and shared decision-making significantly influenced the vision-related quality of life reported by the parents, accounting for 22.5 % of the variance.

Conclusion

The study’s findings emphasize the importance of addressing decision regret and promoting shared decision-making in myopia treatment. Eye care professionals should discuss treatment options thoroughly before making decisions. Through shared decision-making, parents can make informed choices about treatments based on a comprehensive understanding of the benefits and drawbacks, ultimately benefitting children’s vision health.
目的调查 6-12 岁近视儿童的父母在近视治疗、决策后悔、共同决策和视力相关生活质量之间的关系:采用横断面设计制作了一份在线谷歌表格调查问卷,并于 2023 年 1 月 16 日至 8 月 22 日期间发放。通过在台湾工作的学校护士招募了 6-12 岁近视儿童的家长。收集了儿童和家长的人口统计学数据。研究工具包括决策后悔量表、共同决策和视力相关生活质量问卷。研究采用多变量线性回归分析来确定影响视力相关生活质量的因素:在接触的 350 名家长中,对 314 份问卷进行了分析。受访者中,77.39%(n = 243)为母亲,年龄大多大于 40 岁。确诊近视时儿童的平均年龄为 7.12 ± 1.24 岁;46.50% 的儿童患有先天性近视:研究结果强调了在近视治疗中解决决策遗憾和促进共同决策的重要性。眼科专业人员在做出决定前,应充分讨论治疗方案。通过共同决策,家长可以在全面了解利弊的基础上做出明智的治疗选择,最终有利于儿童的视力健康。
{"title":"Shared decision‐making, treatment decision regret, and vision-related quality of life among parents of children with myopia: An online survey in Taiwan","authors":"Li-Chun Chang ,&nbsp;Chi-Chin Sun ,&nbsp;Tzu-Chi Lee ,&nbsp;Ya-Ni Wang ,&nbsp;Li-Ling Liao","doi":"10.1016/j.clae.2024.102283","DOIUrl":"10.1016/j.clae.2024.102283","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the relationships among myopia treatment, decision regret, shared decision-making, and vision-related quality of life among parents of 6–12-year-old children with myopia.</div></div><div><h3>Methods</h3><div>An online Google Forms questionnaire was developed using a cross-sectional design and distributed between January 16 and August 22, 2023. Parents of 6–12-year-old children with myopia were recruited through school nurses working in Taiwan. The children’s and parents’ demographic data were collected. Study instruments included the Decisional Regret Scale, Shared Decision‐Making, and Vision-Related Quality of Life questionnaires. Multivariable linear regression analysis was used to identify factors influencing vision-related quality of life.</div></div><div><h3>Results</h3><div>Of 350 parents contacted, 314 questionnaires were analyzed. Among the respondents, 77.39 % (n = 243) were mothers, and most were aged &gt;40 years. The mean age of children at myopia diagnosis was 7.12 ± 1.24 years; 46.50 % had &lt; − 1.0 diopters of refractive error. Atropine eye drops were the primary treatment; 17.71 % of children were prescribed orthokeratology for myopia control. Parents reported low levels of decision regret and moderate levels of shared decision-making and vision-related quality of life. Children’s age, use of orthokeratology lenses, decision regret, and shared decision-making significantly influenced the vision-related quality of life reported by the parents, accounting for 22.5 % of the variance.</div></div><div><h3>Conclusion</h3><div>The study’s findings emphasize the importance of addressing decision regret and promoting shared decision-making in myopia treatment. Eye care professionals should discuss treatment options thoroughly before making decisions. Through shared decision-making, parents can make informed choices about treatments based on a comprehensive understanding of the benefits and drawbacks, ultimately benefitting children’s vision health.</div></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"47 6","pages":"Article 102283"},"PeriodicalIF":4.1,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
International trends in prescribing extended wear soft contact lenses (2000–2023): An update 增戴型软性隐形眼镜处方的国际趋势(2000-2023 年):更新。
IF 4.1 3区 医学 Q1 OPHTHALMOLOGY Pub Date : 2024-08-05 DOI: 10.1016/j.clae.2024.102285
Philip B. Morgan , Nathan Efron , Craig A Woods , Deborah Jones , Lyndon Jones , Jason J. Nichols

Purpose

Extended wear has long been considered as the ultimate contact lens modality in terms of user convenience. The purpose of this work is to update earlier surveys by describing international trends in extended wear soft lens fitting between 2000 and 2023, inclusive.

Method

An annual contact lens prescribing survey was sent to eye care practitioners in up to 71 countries between 2000 and 2023, inclusive. Data relating to 282,142 soft contact lens fits undertaken in 20 countries returning reliable longitudinal data were analysed in respect of extended wear soft lens fitting.

Results

Over the duration of the work there was a very small decrease in the prescribing of extended wear soft lenses (p < 0.0001). More detailed inspection shows that prescribing of these lenses steadily increased from 5.8 % of all soft lens fits in 2000 to 11.6 % in 2007, then steadily decreased to 5.2 % in 2023. Of all soft contact lenses prescribed to males, 9.2 % were fitted for extended wear, compared with 6.7 % for females (p < 0.0001). The mean age of extended wear soft lens wearers at fitting was 34.7 ± 14.7 years, compared to 31.1. ± 14.10 years for daily soft lens wearers (p < 0.0001). Analysis of 1,948 recent extended wear soft lens fits (2019–2023, inclusive), in terms of material type, revealed that, on average, 86 % and 14 % of extended wear soft lenses were fitted using silicone hydrogel and hydrogel materials, respectively.

Conclusion

A modest increase in extended wear soft lens prescribing from 2000 to 2007 corresponded with the introduction of high oxygen transmissibility silicone hydrogel lenses. However, prescribing of this lens type declined thereafter, probably due to ongoing concerns over their increased rate of microbial keratitis, resulting in a prescribing rate in 2023 (5.2%) that was little different to that observed in 2000 (5.8%).
目的:长期以来,延戴式隐形眼镜一直被认为是方便用户的终极隐形眼镜方式。这项工作的目的是通过描述 2000 年至 2023 年(含 2023 年)期间延戴型软性镜片验配的国际趋势,对之前的调查进行更新:方法:在 2000 年至 2023 年(含 2023 年)期间,向多达 71 个国家的眼科护理从业人员发送年度隐形眼镜处方调查。对 20 个国家的 282,142 例软性隐形眼镜验配数据进行了分析,这些数据均提供了可靠的纵向数据:结果:在研究期间,延戴型软性隐形眼镜的处方量略有减少(p 结论:延戴型软性隐形眼镜的处方量略有增加:从 2000 年到 2007 年,随着高透氧硅水凝胶镜片的推出,延戴型软镜的处方量略有增加。然而,可能是由于人们一直担心这种镜片会增加微生物性角膜炎的发病率,此后这种镜片的处方量有所下降,导致 2023 年的处方率(5.2%)与 2000 年的处方率(5.8%)相差无几。
{"title":"International trends in prescribing extended wear soft contact lenses (2000–2023): An update","authors":"Philip B. Morgan ,&nbsp;Nathan Efron ,&nbsp;Craig A Woods ,&nbsp;Deborah Jones ,&nbsp;Lyndon Jones ,&nbsp;Jason J. Nichols","doi":"10.1016/j.clae.2024.102285","DOIUrl":"10.1016/j.clae.2024.102285","url":null,"abstract":"<div><h3>Purpose</h3><div>Extended wear has long been considered as the ultimate contact lens modality in terms of user convenience. The purpose of this work is to update earlier surveys by describing international trends in extended wear soft lens fitting between 2000 and 2023, inclusive.</div></div><div><h3>Method</h3><div>An annual contact lens prescribing survey was sent to eye care practitioners in up to 71 countries between 2000 and 2023, inclusive. Data relating to 282,142 soft contact lens fits undertaken in 20 countries returning reliable longitudinal data were analysed in respect of extended wear soft lens fitting.</div></div><div><h3>Results</h3><div>Over the duration of the work there was a very small decrease in the prescribing of extended wear soft lenses (p &lt; 0.0001). More detailed inspection shows that prescribing of these lenses steadily increased from 5.8 % of all soft lens fits in 2000 to 11.6 % in 2007, then steadily decreased to 5.2 % in 2023. Of all soft contact lenses prescribed to males, 9.2 % were fitted for extended wear, compared with 6.7 % for females (p &lt; 0.0001). The mean age of extended wear soft lens wearers at fitting was 34.7 ± 14.7 years, compared to 31.1. ± 14.10 years for daily soft lens wearers (p &lt; 0.0001). Analysis of 1,948 recent extended wear soft lens fits (2019–2023, inclusive), in terms of material type, revealed that, on average, 86 % and 14 % of extended wear soft lenses were fitted using silicone hydrogel and hydrogel materials, respectively.</div></div><div><h3>Conclusion</h3><div>A modest increase in extended wear soft lens prescribing from 2000 to 2007 corresponded with the introduction of high oxygen transmissibility silicone hydrogel lenses. However, prescribing of this lens type declined thereafter, probably due to ongoing concerns over their increased rate of microbial keratitis, resulting in a prescribing rate in 2023 (5.2%) that was little different to that observed in 2000 (5.8%).</div></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"47 6","pages":"Article 102285"},"PeriodicalIF":4.1,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Contact Lens & Anterior Eye
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