Brazilian Journal of Otorhinolaryngology最新文献_第5页

Mendelian randomization and FinnGen analysis of the causal relationship between 473 gut microbiota species and chronic sinusitis 473种肠道菌群与慢性鼻窦炎因果关系的孟德尔随机化和FinnGen分析

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-09-25 DOI: 10.1016/j.bjorl.2025.101711

Chenguang Zhang , Yicong Wang , Chenghao Hu , Bin Guo , Huwei Jiang , Chunlong Zhao , Yuwen Wang

Objective

To investigate the causal associations between Gut Microbiota (GM) and Chronic Sinusitis (CRS) using Mendelian Randomization (MR).

Methods

Genome-Wide Association Study (GWAS) summary statistics for 473 GM taxa were obtained from MiBioGen consortium. CRS data (22,099 cases vs. 371,520 controls) were sourced from the FinnGen R12 cohort. Causal effects were estimated via Inverse Variance-Weighted (IVW), MR-Egger, weighted median, and Bayesian-weighted MR methods. Sensitivity analyses (heterogeneity and horizontal pleiotropy tests) were performed to validate robustness.

Results

IVW analysis identified 20 GM taxa significantly associated with CRS risk (p < 0.05). Of these, 7 taxa (e.g., Francisellales, Roseibacillus, Merdibacter massiliensis) exhibited risk-increasing effects, while 13 taxa (e.g., Firmicutes I, Succinivibrionaceae) showed protective effects. Sensitivity analyses confirmed the absence of significant heterogeneity (Cochran’s Q p > 0.05) or pleiotropy (MR-Egger intercept p > 0.05). Bayesian-weighted MR validated 18 causal relationships (posterior probability > 95%), except for RUG420 sp900317985 and UBA7703 (non-significant).

Conclusions

This MR study provides genetic evidence supporting causal roles of specific GM taxa in CRS pathogenesis. These findings highlight the gut-sinus axis as a potential therapeutic target and underscore the utility of large-scale biobanks (e.g., FinnGen) in advancing precision medicine.

Level of evidence

Level 5. Mendelian Randomized (MR) studies are second only to randomized controlled trials in terms of the level of evidence.

目的应用孟德尔随机化（MR）方法探讨肠道菌群（GM）与慢性鼻窦炎（CRS）的因果关系。方法从MiBioGen联盟中获取473个GM分类群的GWAS汇总统计数据。CRS数据（22,099例与371,520例对照）来自FinnGen R12队列。通过反方差加权（IVW）、MR- egger、加权中位数和贝叶斯加权MR方法估计因果效应。进行敏感性分析（异质性和水平多效性试验）以验证稳健性。结果vw分析发现20个GM分类群与CRS风险显著相关（p < 0.05）。其中7个类群（Francisellales、Roseibacillus、Merdibacter massiliensis）表现出增加风险的作用，13个类群（Firmicutes I、Succinivibrionaceae）表现出保护作用。敏感性分析证实不存在显著异质性（Cochran’s Q p > 0.05）或多效性（MR-Egger截距p >； 0.05）。贝叶斯加权MR验证了18个因果关系（后验概率>； 95%），除了RUG420 sp900317985和UBA7703（不显著）。结论本MR研究提供了支持特定转基因分类群在CRS发病机制中的因果作用的遗传学证据。这些发现突出了肠窦轴作为一个潜在的治疗靶点，并强调了大规模生物库（如FinnGen）在推进精准医学方面的效用。证据等级：5级。孟德尔随机（MR）研究在证据水平方面仅次于随机对照试验。

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引用次数: 0

Nomogram for predicting overall and cancer-specific survival in patients with postoperative follicular thyroid cancer 预测滤泡性甲状腺癌术后患者总体和癌症特异性生存的Nomogram

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-09-25 DOI: 10.1016/j.bjorl.2025.101719

Xin Liu , Suidan Chen , Cangui Wu

Objectives

In this research, nomograms were constructed from clinical variables in patients with postoperative Follicular Thyroid Cancer (FTC) to predict the survival of FTC patients.

Methods

Adult patients surgically treated for FTC from 2004 to 2015 were selected from the Surveillance, Epidemiology, and End Results (SEER) database. Significant clinical variables were screened using univariate analysis and further screened with multivariate Cox regression analysis, which were used to construct nomogram models for Overall Survival (OS) and Cancer-Specific Survival (CSS).

Results

Age, sex, marital status, tumor size, glandular invasion status, N stage and M stage were identified as the clinical variables affecting the OS in FTC patients. Additionally, all variables, except sex, were found to have an impact on the CSS in FTC patients. The c-index shows agreement between the predicted results and the actual observed results, and the calibration curve of the probability of survival also shows agreement between the predicted plot and the actual observations.

Conclusions

Our study successfully built a nomogram of OS and CSS for FTC patients who had undergone surgery.

Level of evidence

IV: Retrospective cohort study.

目的通过对术后滤泡性甲状腺癌（FTC）患者的临床变量进行形态学分析，以预测FTC患者的生存。方法从监测、流行病学和最终结果（SEER）数据库中选择2004 - 2015年手术治疗的成年FTC患者。采用单因素分析筛选有意义的临床变量，并进一步采用多因素Cox回归分析筛选，构建总生存期（OS）和癌症特异性生存期（CSS）的nomogram模型。结果年龄、性别、婚姻状况、肿瘤大小、腺体浸润情况、N分期、M分期是影响FTC患者OS的临床变量。此外，除性别外，所有变量都对FTC患者的CSS有影响。c指数表明预测结果与实际观测结果吻合，生存概率校正曲线也表明预测图与实际观测值吻合。结论我们的研究成功构建了FTC手术患者的OS和CSS的nomogram。证据水平iv：回顾性队列研究。

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引用次数: 0

Estrogenic/Progestin therapy and the development of Vestibular Schwannoma: A systematic review and meta-analysis 雌激素/黄体酮治疗与前庭神经鞘瘤的发展：一项系统综述和荟萃分析

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-09-25 DOI: 10.1016/j.bjorl.2025.101706

Maria Vitória Graça Couto de Campos Amaral, Fayez Bahmad Jr

Objective

Compare the risk of developing Vestibular schwannoma in patients prescribed Hormone Therapy (HT).

Methods

We performed a systematic review in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA), the search was conducted in English, and we included all the studies that met the following criteria: (a) Participants who presented with VS; (b) Patients prescribed Hormone Replacement Therapy (HRT); (c) Prospective, retrospective or case-control study.

Results

Of the 146 articles, four met the inclusion criteria and were included in the systematic review and meta-analysis. Two studies documented an increased relative risk of Vestibular schwannoma in patients that had ever used hormone replacement therapy, another study found an incidence rate 2.2 times higher than the expected incidence rate and the other study indicated a 10% increased odds of the Vestibular Schwannoma in patients who have ever used hormone replacement therapy.

Conclusion

The use of hormone replacement therapy was associated with an increased relative risk of Vestibular Schwannoma but also demonstrated a lack of a definitive association.

Level of evidence

Level 1.

目的比较激素治疗（HT）患者发生前庭神经鞘瘤的风险。方法：我们按照系统评价和荟萃分析的首选报告项目（PRISMA）进行了系统评价，检索是用英文进行的，我们纳入了符合以下标准的所有研究：(a)出现VS的参与者；(b)给病人开的激素替代疗法；(c)前瞻性、回顾性或病例对照研究。结果146篇文章中，有4篇符合纳入标准，被纳入系统评价和meta分析。两项研究表明，曾经使用激素替代疗法的患者患前庭神经鞘瘤的相对风险增加，另一项研究发现，发病率比预期的发病率高2.2倍，另一项研究表明，曾经使用激素替代疗法的患者患前庭神经鞘瘤的几率增加10%。结论激素替代疗法的使用与前庭神经鞘瘤的相对风险增加有关，但也缺乏明确的联系。证据等级：1级。

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引用次数: 0

Cochlear size variation among the Argentinian population 阿根廷人群中耳蜗大小的变化

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-09-10 DOI: 10.1016/j.bjorl.2025.101708

Maria Fernanda Di Gregorio , Ana Celeste Ferrari , Anandhan Dhanasingh , Maximo Zernotti , Mario Zernotti

Objective

Cochlear size, shape and the anatomy vary a lot among the human population. Cochlear size is a clinically useful parameter to determine the suitable cochlear implant electrode length. Objective is to assess the cochlear size and shape variation among the Argentine population.

Methods

Computer Tomography (CT) scans of 247 ears were assessed for the cochlear parameters including basal turn diameter (A-value) and width (B-value) and the cochlear height in the mid-modiolar section (H-value) using OTOPLAN® version 4.0. Shape of cochlear basal turn was determined by the ratio between B- and A-values. Cochlear Duct Length (CDL) was estimated from the A-, and B-values.

Results

The A-value was found to vary between 6.7 mm and 10.1 mm with a mean value of 8.7 ± 0.61 mm and the B-value was found to vary between 4.5 mm and 8.1 mm with a mean value of 6.4 ± 0.57 mm. The cochlear height as measured in the axial view from the mid-modiolar section was 3.78 ± 0.57 mm. Shape of the cochlear basal turn as determined by the ratio between B- and A-values showed 41 out of 248 ears (16.5%) have more of a round shaped basal turn with the ratio of ≥0.75 leaving the remaining 207 ears (83.5%) with more of an elliptical shaped basal turn. CDL was found to vary between 24.5 mm and 41.2 mm with a median value of 33.6 mm.

Conclusion

Argentine population appears to have slightly smaller cochlear size compared to population from other countries as reported in literature.

Level of evidence

3.

目的：不同人群的耳蜗大小、形状和解剖结构差异很大。耳蜗大小是临床上确定合适的人工耳蜗电极长度的重要参数。目的是评估阿根廷人群中耳蜗大小和形状的变化。方法采用OTOPLAN®4.0版本对247只耳蜗进行CT扫描，评估耳蜗基底转径（a值）、宽度（b值）和耳蜗中磨牙段高度（h值）等参数。通过B值与a值之比确定耳蜗基底转形状。根据A值和b值估计耳蜗管长度（CDL）。结果a值在6.7 ~ 10.1 mm之间变化，平均值为8.7±0.61 mm； b值在4.5 ~ 8.1 mm之间变化，平均值为6.4±0.57 mm。中磨牙切面轴向位测耳蜗高度为3.78±0.57 mm。B值与a值之比测定耳蜗基底转形状：248耳中有41耳（16.5%）的基底转以圆形为主，比值≥0.75，其余207耳（83.5%）的基底转以椭圆形为主。CDL在24.5 mm和41.2 mm之间变化，中位值为33.6 mm。结论阿根廷人群的耳蜗尺寸与文献报道的其他国家人群相比略小。证据水平3。

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引用次数: 0

High frequency of balance abnormalities in Turner syndrome 特纳综合征平衡性异常的高频率

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-09-10 DOI: 10.1016/j.bjorl.2025.101713

Vanessa Brito Campoy Rocha , Raquel Mezzalira , Guita Stoler , Gil Guerra-Junior , Sofia Helena Valente de Lemos-Marini , Andréa Trevas Maciel-Guerra

Objective

To perform a thorough evaluation of body balance in Turner Syndrome, adding evidence to the already scarce data in literature regarding labyrinth impairment in these patients.

Methods

Adolescent and adult patients and a control group of healthy women were subject to otolaryngological, audiological, and vestibular evaluations. The latter included electronystagmography with caloric and rotational testing, cervical vestibular-evoked myogenic potential and static posturography with dynamic tests.

Results

Twenty-seven patients aged 15–33 years (mean: 21.9-years) were evaluated. Karyotype was 45,X in 13/27 cases. Dizziness was reported in eight patients and progressive hearing loss in ten. Audiometry was abnormal in 13/27 cases, six of them sensorineural, six conductive, and one with a mixed pattern. A balance abnormality was found in 21/27 patients (78%). Nineteen patients had vestibular lesion, [12 peripheral (57%), four combined (19%), three central (11%)] and two had only somatosensorial deficit. Non-vestibular abnormalities were found in 6 (22%) patients, five with somatosensorial deficit and one with visual dependence. Balance abnormalities were neither associated with karyotype (45,X vs. other karyotypes) nor with hearing impairment. Control group comprised 20 healthy women aged 27–35 years (mean: 30.5 years); 4/20 (25%) had a balance abnormality, two peripheral and two central causes, a frequency significantly lower than that of TS patients (p < 0.001).

Conclusion

Despite the low frequency of self-reported vestibular and auditory symptoms, this study reveals a high rate of inner ear involvement among women with TS, in which both auditory and vestibular pathways are frequently affected, often in a subclinical or compensated manner. These findings reinforce the importance of comprehensive screening protocols and indicate that appropriate interventions, including vestibular rehabilitation, should be considered as components of clinical follow-up in this population.

Level of Evidence

4.

目的对特纳综合征患者的身体平衡进行全面的评估，为文献中关于该患者迷宫损伤的数据补充证据。方法采用耳鼻喉科、听力学和前庭功能检查对青少年、成年患者和健康女性进行对照。后者包括含热量和旋转测试的眼震电图、颈前庭诱发肌电位和含动态测试的静态体位图。结果本组患者27例，年龄15 ~ 33岁，平均21.9岁。核型为45x， 13/27例。8名患者报告头晕，10名患者报告进行性听力丧失。听力学异常13/27例，感音神经性6例，传导性6例，混合型1例。27例患者中有21例（78%）出现平衡异常。前庭病变19例，外周病变12例（57%），合并病变4例（19%），中枢病变3例（11%），仅有体感功能障碍2例。6例（22%）患者无前庭功能异常，5例有体感障碍，1例有视觉依赖。平衡异常与核型无关（45，X与其他核型），也与听力障碍无关。对照组为20名27-35岁的健康女性（平均30.5岁）；4/20（25%）有平衡异常，2个外周原因和2个中心原因，频率显著低于TS患者（p < 0.001）。结论：尽管自我报告的前庭和听觉症状的频率较低，但本研究揭示了TS女性内耳受累的高发生率，其中听觉和前庭通路经常受到影响，通常以亚临床或代偿方式。这些发现加强了全面筛查方案的重要性，并表明适当的干预措施，包括前庭康复，应被视为该人群临床随访的组成部分。证据水平

{"title":"High frequency of balance abnormalities in Turner syndrome","authors":"Vanessa Brito Campoy Rocha , Raquel Mezzalira , Guita Stoler , Gil Guerra-Junior , Sofia Helena Valente de Lemos-Marini , Andréa Trevas Maciel-Guerra","doi":"10.1016/j.bjorl.2025.101713","DOIUrl":"10.1016/j.bjorl.2025.101713","url":null,"abstract":"<div><h3>Objective</h3><div>To perform a thorough evaluation of body balance in Turner Syndrome, adding evidence to the already scarce data in literature regarding labyrinth impairment in these patients.</div></div><div><h3>Methods</h3><div>Adolescent and adult patients and a control group of healthy women were subject to otolaryngological, audiological, and vestibular evaluations. The latter included electronystagmography with caloric and rotational testing, cervical vestibular-evoked myogenic potential and static posturography with dynamic tests.</div></div><div><h3>Results</h3><div>Twenty-seven patients aged 15–33 years (mean: 21.9-years) were evaluated. Karyotype was 45,X in 13/27 cases. Dizziness was reported in eight patients and progressive hearing loss in ten. Audiometry was abnormal in 13/27 cases, six of them sensorineural, six conductive, and one with a mixed pattern. A balance abnormality was found in 21/27 patients (78%). Nineteen patients had vestibular lesion, [12 peripheral (57%), four combined (19%), three central (11%)] and two had only somatosensorial deficit. Non-vestibular abnormalities were found in 6 (22%) patients, five with somatosensorial deficit and one with visual dependence. Balance abnormalities were neither associated with karyotype (45,X vs. other karyotypes) nor with hearing impairment. Control group comprised 20 healthy women aged 27–35 years (mean: 30.5 years); 4/20 (25%) had a balance abnormality, two peripheral and two central causes, a frequency significantly lower than that of TS patients (p < 0.001).</div></div><div><h3>Conclusion</h3><div>Despite the low frequency of self-reported vestibular and auditory symptoms, this study reveals a high rate of inner ear involvement among women with TS, in which both auditory and vestibular pathways are frequently affected, often in a subclinical or compensated manner. These findings reinforce the importance of comprehensive screening protocols and indicate that appropriate interventions, including vestibular rehabilitation, should be considered as components of clinical follow-up in this population.</div></div><div><h3>Level of Evidence</h3><div>4.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"92 1","pages":"Article 101713"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Competencies in head and neck surgery teaching for specialty residents. Position statement of Brazilian Head and Neck Surgery Society 头颈外科专科住院医师的教学能力。巴西头颈外科学会立场声明

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-09-13 DOI: 10.1016/j.bjorl.2025.101710

Rogério Aparecido Dedivitis , Mario Augusto Ferrari de Castro , Fátima Cristina Mendes de Matos , Marianne Yumi Nakai , Leandro Luongo de Matos , Marco Aurélio Vamondes Kulcsar , Carlos Takahiro Chone , Luiz Paulo Kowalski , Fernando Luiz Dias , André Cruz Martins , Bruna Carteiro Silva

Objectives

To standardize the necessary competencies for Head and Neck Surgery residents related to the specialty.

Methods

The Delphi process was employed in its sequential phases: the selection of an expert panel; a structured questionnaire containing a preliminary list of potential competencies; the electronic distribution of the questionnaire to the experts, with options to “maintain”, “remove”, or “modify” the competencies and to suggest the inclusion of new competencies; a second round indicating “agree” or “disagree” for each reformulated or new competency; and the final consensus.

Results

Forty-six competencies were established for Head and Neck Surgery residents in the specialty.

Conclusion

Head and Neck Surgery residents and fellows should be trained in depth for the competency framework encompassing both routine and complex surgical interventions.

Level of evidence

5.

目的规范头颈外科住院医师与本专业相关的必要能力。方法采用德尔菲法，选取专家小组；一份包含潜在能力初步清单的结构化问卷；以电子方式向专家分发调查问卷，选择“保留”、“删除”或“修改”能力，并建议列入新的能力；第二轮对每一个重新表述的或新的能力表示“同意”或“不同意”；最后的共识。结果为头颈外科住院医师建立了46项胜任能力。结论头颈外科住院医师和实习医师应深入学习包括常规和复杂手术干预在内的能力框架。证据水平。

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引用次数: 0

A case-control study on preauricular congenital fistula surgery outcomes by Propensity Score Matching (PSM) analysis 倾向评分匹配（PSM）分析耳前先天性瘘手术结果的病例对照研究

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-11-26 DOI: 10.1016/j.bjorl.2025.101729

Jibing Sun, Tingting Wang, Dong Chen, Yanyan Mao, Zhaomin Fan, Yuechen Han

Objective

To explore the propensity matching score to compare the clinical efficacy of infection localized and inflammatory quiescent stage I surgery in the treatment of congenital preauricular fistula.

Methods

120 patients with congenital preauricular fistula treated in our hospital from January 2022 to August 2023 were selected. The patients were divided into infection limited group (n = 63) and inflammation rest group (n = 57) according to the mode of operation. The two groups were matched at 1:1 with Propensity Score Matching (PSM) method, and finally included in infection limitation group and inflammation rest group (n = 50). Patients in both groups were treated with stage I operation.

Results

Before PSM, there were significant differences between the two groups in terms of gender, age, BMI, and the number of patients with previous infection requiring incision and drainage (p < 0.05). After PSM, there were no statistically significant differences in general information between the two groups (p > 0.05). There was no significant difference in healing, incidence of postoperative complications and recurrence rate between the two groups (p > 0.05).

Conclusion

There is no significant difference in the clinical efficacy comparison of surgical treatment for congenital preauricular fistula between the infection-localized phase and inflammation-quiescent stage I surgery with PSM.

Level of Evidence

Level 3.

目的探讨倾向匹配评分，比较局部感染与炎性静止I期手术治疗先天性耳前瘘的临床疗效。方法选择2022年1月~ 2023年8月我院收治的先天性耳前瘘患者120例。根据手术方式分为限制感染组（n = 63）和炎症休止组（n = 57）。采用倾向评分匹配法（Propensity Score Matching， PSM）将两组按1:1进行匹配，最终分为感染限制组和炎症休息组（n = 50）。两组患者均行一期手术治疗。结果PSM治疗前，两组患者在性别、年龄、BMI、既往感染需要切开引流患者数量等方面差异均有统计学意义（p < 0.05）。PSM后，两组一般信息比较，差异无统计学意义（p > 0.05）。两组患者愈合、术后并发症发生率及复发率比较，差异均无统计学意义（p > 0.05）。结论PSM治疗先天性耳前瘘感染局限期与炎症静止期手术治疗的临床疗效比较无显著差异。证据等级：3级。

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引用次数: 0

Posturography techniques to identify balance problems in elderly individuals with vestibulopathy – a comparison study 体位摄影技术识别老年前庭病变患者平衡问题的比较研究

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-11-26 DOI: 10.1016/j.bjorl.2025.101743

Cibele Brugnera , Raquel Mezzalira , Lucas Resende Lucinda Mangia , Luiz Cezar da Silveira , Bruno Souza , Roseli Saraiva Moreira Bittar

Objective

To compare the postugraphic outcomes of two different methods in four basic postural conditions.

Methods

The individuals with vestibular disorders were divided into two subgroups according to their age: more than 60-years old and aged between 18 and 60. All the participants underwent to computerized dynamic posturography (EquiTest System®) and a mobile posturography (Vertiguard System®) in four test conditions: (1) Eyes open and stable surface, (2) Eyes closed and stable surface, (4) Eyes open and unstable surface, (5) Eyes closed and unstable surface.

Results

The elderly group presented worse overall outcomes in computerized dynamic posturography compared to controls. These outcomes were not different between groups when mobile posturography was used. For both methods, the results were not different between groups when the Conditions 1, 2 and 5 were evaluated separately. A significantly higher proportion of elderly subjects exhibited alterations in C4 during mobile posturography.

Conclusion

Computerized dynamic posturography was overall more sensitive at detecting abnormal postural sway in elderly individuals with vestibular disorders. In mobile posturography, Condition 4 also seemed particularly sensitive at detecting postural instability.

Level of evidence

2.

目的比较两种方法在四种基本体位条件下的体位成像效果。方法将前庭功能障碍患者按年龄分为60岁以上和18 ~ 60岁两组。所有参与者在四种测试条件下进行了计算机动态体位记录（EquiTest System®）和移动体位记录（Vertiguard System®）：(1)睁眼和稳定表面，(2)闭眼和稳定表面，(4)睁眼和不稳定表面，(5)闭眼和不稳定表面。结果与对照组相比，老年组在计算机动态体位照相中的总体结果较差。当使用移动姿势照相时，这些结果在两组之间没有差异。两种方法分别评价条件1、条件2和条件5时，两组结果均无差异。老年受试者在移动姿势时C4发生改变的比例明显更高。结论计算机动态体位术对老年前庭疾病患者异常体位摆动的检测总体上更为灵敏。在移动姿势照相中，Condition 4在检测姿势不稳定方面似乎也特别敏感。证据水平2。

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引用次数: 0

Generative artificial intelligence in otorhinolaryngology: From innovation to public health transformation 耳鼻喉科的生成式人工智能：从创新到公共卫生转型

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-09-11 DOI: 10.1016/j.bjorl.2025.101714

Alexandre Vallée

引用次数: 0

Tomographic comparison of the cochlea, oval window, round window and facial nerve between adults and children and their influence on cochlear implant surgery 成人与儿童耳蜗、卵形窗、圆形窗和面神经的断层扫描比较及其对人工耳蜗手术的影响

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2026-01-01 Epub Date: 2025-10-24 DOI: 10.1016/j.bjorl.2025.101731

Rogerio Hamerschmidt , Mohamad Feras Al-lahham , Bettina Carvalho , Mayara Risnei Watanabe , Rogério de Azevedo Hamerschmidt , Isadora Mansur Castro

Objective

Is to compare two tomographic measurements that can be used to predict the visibility of the round window: the angle formed by the junction of the line that goes from the round window Membrane Center Point (MJR) to the Facial Nerve surface (FN) with the Coronal Plane (CP) traced over this surface (RWM-FN-CP Angle) and the vertical distance between the midpoint of the RWM and this Coronal Plane (RWM-CP Vertical Distance); in adults and children, in order to verify if there are significant differences between the groups, which would justify the greater surgical difficulty caused by the lower visibility of the RW in children.

Methods

In this retrospective study, the RWM-FN-CP angle and the RWM-CP vertical distance were measured in Computerized Tomography Scans (CT) of patients who underwent CI surgeries.

Results

32 individuals who underwent CT in the period 2015–2018, 16 adults aged 27–73 years, and 16 children, with a mean age of 3.4 (±2.7) years were evaluated. The mean of the RWM-FN-CP angle in children was significantly lower, than the mean in adults. The mean RWM-CP vertical distance in children was significantly lower than the mean in adults (p = 0.0001).

Conclusion

In children, the RWM-FN-CP angle is more acute, and the measured MJR-PC vertical distance is smaller when compared to adults. The anatomical differences observed in the tomographies justify the lower visibility of the RW during the surgical act of cochlear implantation in children.

Level of evidence

3.

目的比较两种可用于预测圆形窗口可见性的层析测量方法：圆形窗口膜中心点（MJR）与面神经表面（FN）的连线与该表面上的冠状面（CP）的连接处形成的角度（RWM-FN-CP角）和RWM中点与该冠状面之间的垂直距离（RWM-CP垂直距离）；在成人和儿童中，为了验证两组之间是否存在显著差异，这将证明儿童RW能见度较低导致手术难度较大。方法回顾性研究行CI手术患者的RWM-FN-CP角和RWM-CP垂直距离。结果2015-2018年接受CT治疗的32例患者，其中成人16例，年龄27-73岁，儿童16例，平均年龄3.4（±2.7）岁。儿童RWM-FN-CP角的平均值明显低于成人。儿童RWM-CP垂直距离均值显著低于成人（p = 0.0001）。结论与成人相比，儿童RWM-FN-CP角度更尖锐，测得MJR-PC垂直距离更小。在断层扫描中观察到的解剖差异证明了在儿童人工耳蜗植入手术过程中RW的能见度较低。证据水平3。

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引用次数: 0