Objective: This study aimed to evaluate and compare the outcomes of patients undergoing video-assisted thyroidectomy versus those undergoing traditional open surgery.
Methods: In this retrospective study, we reviewed the clinical records of 449 patients who underwent thyroid surgery at our institution between April 2017 and March 2022. Of these, 209 underwent video-assisted thyroidectomy, while 248 underwent traditional open surgery. After excluding those who received total thyroidectomy, central node dissection, or lateral node dissection, we focused our analysis on 136 patients with video-assisted lobectomy and 92 patients with traditional open surgery. We compared patient outcomes, including surgical results and adverse events, between these groups.
Results: Significant differences were observed in the maximum tumor diameter between the video-assisted lobectomy and traditional open surgery groups. However, no significant differences were noted in surgical time, bleeding, or adverse events.
Conclusion: Video-Assisted Neck Surgery (VANS) offers great cosmetic benefits and is comparable to traditional open surgery in terms of adverse events.
{"title":"Comparative outcomes of video-assisted thyroidectomy and traditional open surgery: a 5-year analysis of a single center experience.","authors":"Kenzo Ohara, Takumi Kumai, Kan Kishibe, Hidekiyo Yamaki, Hiroki Komatsuda, Tatsuya Hayashi, Miki Takahara","doi":"10.1016/j.bjorl.2024.101539","DOIUrl":"10.1016/j.bjorl.2024.101539","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate and compare the outcomes of patients undergoing video-assisted thyroidectomy versus those undergoing traditional open surgery.</p><p><strong>Methods: </strong>In this retrospective study, we reviewed the clinical records of 449 patients who underwent thyroid surgery at our institution between April 2017 and March 2022. Of these, 209 underwent video-assisted thyroidectomy, while 248 underwent traditional open surgery. After excluding those who received total thyroidectomy, central node dissection, or lateral node dissection, we focused our analysis on 136 patients with video-assisted lobectomy and 92 patients with traditional open surgery. We compared patient outcomes, including surgical results and adverse events, between these groups.</p><p><strong>Results: </strong>Significant differences were observed in the maximum tumor diameter between the video-assisted lobectomy and traditional open surgery groups. However, no significant differences were noted in surgical time, bleeding, or adverse events.</p><p><strong>Conclusion: </strong>Video-Assisted Neck Surgery (VANS) offers great cosmetic benefits and is comparable to traditional open surgery in terms of adverse events.</p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"101539"},"PeriodicalIF":1.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-11DOI: 10.1016/j.bjorl.2024.101542
Wildna Sharon Martins da Costa, Lucas Barbosa de Araújo, Henrique de Paula Bedaque, Lidiane Maria de Brito Macedo Ferreira, Karyna Myrelly Oliveira Bezerra de Figueiredo Ribeiro
Objective: To assess the impact of the somatosensory influence on annoyance and quality of life of individuals with tinnitus.
Methods: This cross-sectional study included individuals with tinnitus of both sexes, aged ≥18 years, recruited from a specialized otolaryngology outpatient, and evaluated by a multidisciplinary team (otorhinolaryngologists, physical therapists, and audiologists). An evaluation adapted from the Diagnostic Criteria of Somatosensory Tinnitus (ST) was performed to verify the influence of the somatosensory system on the cause of tinnitus. The intensity of discomfort from tinnitus was assessed by the Numerical Rating Scale, the impact on quality of life by the Tinnitus Handicap Inventory (THI), and factors of exacerbation of tinnitus were self-reported. Individuals were divided into ST and non-ST groups. Unpaired t-test and Chi-Square were used for group comparisons; Cohen's d and Phi measured effect sizes.
Results: A total of 100 individuals were evaluated: 46 from the ST group and 54 from the non-ST group. The ST group demonstrated greater discomfort from tinnitus (p < 0.01); stress was identified as a factor of exacerbation 82.6 (p < 0.01), and sleep disturbance as a consequence of tinnitus 63% (p = 0.04). Additionally, the ST group presented a greater impact on quality of life in the functional domain (p = 0.03) and total THI score (p = 0.05) than the non-ST group.
Conclusion: Individuals with ST reported greater discomfort from tinnitus and a more significant impact on the quality of life.
目的：评估体感对耳鸣患者的烦恼和生活质量的影响：评估体感对耳鸣患者的烦恼和生活质量的影响：这项横断面研究包括从耳鼻喉科专科门诊招募的年龄≥18 岁的男女耳鸣患者，并由多学科团队（耳鼻喉科医生、理疗师和听力学家）进行评估。评估采用了体感耳鸣诊断标准（ST），以验证体感系统对耳鸣原因的影响。耳鸣造成的不适感强度由数字评分量表评估，对生活质量的影响由耳鸣障碍量表（THI）评估，耳鸣加重的因素由患者自我报告。患者被分为ST组和非ST组。组间比较采用非配对 t 检验和 Chi-Square 检验；Cohen's d 和 Phi 衡量效应大小：共有 100 人接受了评估：ST 组 46 人，非 ST 组 54 人。ST组患者的耳鸣不适感更强（P 结论：ST组患者的耳鸣不适感更强，而非ST组患者的耳鸣不适感更弱：ST组患者的耳鸣不适感更强，对生活质量的影响更大。
{"title":"Impact of the somatosensory influence on annoyance and quality of life of individuals with tinnitus: A cross-sectional study.","authors":"Wildna Sharon Martins da Costa, Lucas Barbosa de Araújo, Henrique de Paula Bedaque, Lidiane Maria de Brito Macedo Ferreira, Karyna Myrelly Oliveira Bezerra de Figueiredo Ribeiro","doi":"10.1016/j.bjorl.2024.101542","DOIUrl":"10.1016/j.bjorl.2024.101542","url":null,"abstract":"<p><strong>Objective: </strong>To assess the impact of the somatosensory influence on annoyance and quality of life of individuals with tinnitus.</p><p><strong>Methods: </strong>This cross-sectional study included individuals with tinnitus of both sexes, aged ≥18 years, recruited from a specialized otolaryngology outpatient, and evaluated by a multidisciplinary team (otorhinolaryngologists, physical therapists, and audiologists). An evaluation adapted from the Diagnostic Criteria of Somatosensory Tinnitus (ST) was performed to verify the influence of the somatosensory system on the cause of tinnitus. The intensity of discomfort from tinnitus was assessed by the Numerical Rating Scale, the impact on quality of life by the Tinnitus Handicap Inventory (THI), and factors of exacerbation of tinnitus were self-reported. Individuals were divided into ST and non-ST groups. Unpaired t-test and Chi-Square were used for group comparisons; Cohen's d and Phi measured effect sizes.</p><p><strong>Results: </strong>A total of 100 individuals were evaluated: 46 from the ST group and 54 from the non-ST group. The ST group demonstrated greater discomfort from tinnitus (p < 0.01); stress was identified as a factor of exacerbation 82.6 (p < 0.01), and sleep disturbance as a consequence of tinnitus 63% (p = 0.04). Additionally, the ST group presented a greater impact on quality of life in the functional domain (p = 0.03) and total THI score (p = 0.05) than the non-ST group.</p><p><strong>Conclusion: </strong>Individuals with ST reported greater discomfort from tinnitus and a more significant impact on the quality of life.</p>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"101542"},"PeriodicalIF":1.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-11DOI: 10.1016/j.bjorl.2024.101540
Fetih Furkan Şahin, İsa Kaya, Hakan Ceylan, Tayfun Kirazlı
Objective: This study aimed to assess the efficacy of a novel modified asymmetric chondro-perichondrial island graft in tympanoplasty. The design features a longer anterior segment compared to the posterior segment, addressing limitations of symmetrical grafts. We investigated the impact of this modified graft on hearing improvement and graft success rates in patients undergoing tympanoplasty surgery.
Methods: This retrospective study evaluated 784 patients with chronic otitis media who underwent primary type I tympanoplasty with a modified asymmetric chondro-perichondrial island graft technique. Demographics and characteristics of all patients, preoperative location of the perforation, and Pure-Tone Audiometry (PTA) were assessed preoperatively, and graft success and postoperative hearing outcomes were evaluated at the 12-month follow-up.
Results: This study evaluated the efficacy of a modified asymmetric chondro-perichondrial island graft in tympanoplasty. In 784 patients, the mean 12-month postoperative Air-Bone Gap (ABG) improvement was 17.3 dB with a 99% graft success rate. Preoperative ABG significantly improved from 24 dB to 6.6 dB postoperatively (p < 0.001). Perforation location did not affect ABG improvement (p = 0.193) but did influence graft success rate (p < 0.001). No sensorineural hearing loss, retraction pockets, or cholesteatoma were observed postoperatively.
Conclusion: Tympanoplasty offers a well-established surgical approach for restoring hearing function and preventing recurrent otorrhea. The asymmetric cartilage-perichondrium island graft design has emerged as a promising technique to achieve optimal functional and anatomical outcomes in tympanoplasty.
{"title":"The modified asymmetric chondro-perichondrial island graft in type I tympanoplasty: A retrospective analysis of 784 patients.","authors":"Fetih Furkan Şahin, İsa Kaya, Hakan Ceylan, Tayfun Kirazlı","doi":"10.1016/j.bjorl.2024.101540","DOIUrl":"10.1016/j.bjorl.2024.101540","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the efficacy of a novel modified asymmetric chondro-perichondrial island graft in tympanoplasty. The design features a longer anterior segment compared to the posterior segment, addressing limitations of symmetrical grafts. We investigated the impact of this modified graft on hearing improvement and graft success rates in patients undergoing tympanoplasty surgery.</p><p><strong>Methods: </strong>This retrospective study evaluated 784 patients with chronic otitis media who underwent primary type I tympanoplasty with a modified asymmetric chondro-perichondrial island graft technique. Demographics and characteristics of all patients, preoperative location of the perforation, and Pure-Tone Audiometry (PTA) were assessed preoperatively, and graft success and postoperative hearing outcomes were evaluated at the 12-month follow-up.</p><p><strong>Results: </strong>This study evaluated the efficacy of a modified asymmetric chondro-perichondrial island graft in tympanoplasty. In 784 patients, the mean 12-month postoperative Air-Bone Gap (ABG) improvement was 17.3 dB with a 99% graft success rate. Preoperative ABG significantly improved from 24 dB to 6.6 dB postoperatively (p < 0.001). Perforation location did not affect ABG improvement (p = 0.193) but did influence graft success rate (p < 0.001). No sensorineural hearing loss, retraction pockets, or cholesteatoma were observed postoperatively.</p><p><strong>Conclusion: </strong>Tympanoplasty offers a well-established surgical approach for restoring hearing function and preventing recurrent otorrhea. The asymmetric cartilage-perichondrium island graft design has emerged as a promising technique to achieve optimal functional and anatomical outcomes in tympanoplasty.</p><p><strong>Level of evidence: </strong>Level 4.</p>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"101540"},"PeriodicalIF":1.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-29DOI: 10.1016/j.bjorl.2024.101538
Jérôme R. Lechien , Luigi A. Vaira , Bianca M. Georgescu , Antonino Maniaci , Stéphane Hans , Sven Saussez
{"title":"Recovery of misattributed congenital anosmia after platelet-rich plasma injections: Report of two cases","authors":"Jérôme R. Lechien , Luigi A. Vaira , Bianca M. Georgescu , Antonino Maniaci , Stéphane Hans , Sven Saussez","doi":"10.1016/j.bjorl.2024.101538","DOIUrl":"10.1016/j.bjorl.2024.101538","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101538"},"PeriodicalIF":1.7,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-19DOI: 10.1016/j.bjorl.2024.101534
Ling Tian , Min Zhao , Qing Yang , Xiaojiang Li , Yun Chen , Xifang Wu , Yan-Xin Ren
Objective
This study aimed to examine the correlation between smoking, alcohol drinking, and the prognosis of Nasopharyngeal Carcinoma (NPC).
Methods
Clinical data from 721 NPC cases treated at our hospital between January 2005 and December 2010 were collected. Information on smoking and drinking, including duration, daily quantity, and cumulative amount, was recorded and graded according to WHO standards. Statistical analysis was performed to assess the influence of smoking and alcohol drinking on NPC patient prognosis. After controlling for confounding factors, survival analysis compared the 5-year Progression-Free Survival rate (PFS) and Overall Survival rate (OS) among patients with varying degrees of smoking and drinking. The association between smoking, drinking, cumulative amount, and NPC patient prognosis was evaluated. Multivariate Cox regression analysis was then employed, considering patient demographic characteristics and clinical features, to comprehensively analyze prognostic influencing factors in NPC patients. Additionally, the multivariate Cox regression analysis was utilized to comprehensively examine the influencing factors of prognosis, taking into account the patients' basic demographic characteristics and clinical features. The findings revealed significant differences in the aforementioned rates.
Results
(1) Analysis of PFS and OS differences in NPC patients considered smoking status, smoking duration, daily smoking quantity, and cumulative smoking amount. No significant influence of smoking on NPC patient PFS and OS within 5-years was observed (p > 0.05). (2) Non-drinkers with NPC exhibited higher 5-year PFS and OS rates compared to drinkers (p = 0.047, p = 0.026). Furthermore, non-drinkers and those with a drinking duration of less than 120 months or between 120–240 months showed higher 5-year PFS and OS rates than individuals with a drinking duration exceeding 240 months (p < 0.05). Similarly, non-drinkers and individuals consuming less than 50 g/day had higher 5-year PFS and OS rates compared to those consuming 50–100 g/day or more than 100 g/day (p < 0.05). Additionally, the 5-year PFS and OS rates were higher in the non-drinking and light drinking groups compared to the moderate and heavy drinking groups (p < 0.05). (3) A partial synergistic effect between smoking and alcohol drinking was observed in NPC. (4) Alcohol drinking emerged as an independent prognostic factor for NPC.
Conclusion
Alcohol drinking is a significant factor influencing the prognosis of nasopharyngeal carcinoma, with the adverse effects further amplified when combined with smoking.
{"title":"Impact of smoking and alcohol drinking on the prognosis of 721 nasopharyngeal carcinoma","authors":"Ling Tian , Min Zhao , Qing Yang , Xiaojiang Li , Yun Chen , Xifang Wu , Yan-Xin Ren","doi":"10.1016/j.bjorl.2024.101534","DOIUrl":"10.1016/j.bjorl.2024.101534","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to examine the correlation between smoking, alcohol drinking, and the prognosis of Nasopharyngeal Carcinoma (NPC).</div></div><div><h3>Methods</h3><div>Clinical data from 721 NPC cases treated at our hospital between January 2005 and December 2010 were collected. Information on smoking and drinking, including duration, daily quantity, and cumulative amount, was recorded and graded according to WHO standards. Statistical analysis was performed to assess the influence of smoking and alcohol drinking on NPC patient prognosis. After controlling for confounding factors, survival analysis compared the 5-year Progression-Free Survival rate (PFS) and Overall Survival rate (OS) among patients with varying degrees of smoking and drinking. The association between smoking, drinking, cumulative amount, and NPC patient prognosis was evaluated. Multivariate Cox regression analysis was then employed, considering patient demographic characteristics and clinical features, to comprehensively analyze prognostic influencing factors in NPC patients. Additionally, the multivariate Cox regression analysis was utilized to comprehensively examine the influencing factors of prognosis, taking into account the patients' basic demographic characteristics and clinical features. The findings revealed significant differences in the aforementioned rates.</div></div><div><h3>Results</h3><div>(1) Analysis of PFS and OS differences in NPC patients considered smoking status, smoking duration, daily smoking quantity, and cumulative smoking amount. No significant influence of smoking on NPC patient PFS and OS within 5-years was observed (<em>p</em> > 0.05). (2) Non-drinkers with NPC exhibited higher 5-year PFS and OS rates compared to drinkers (<em>p</em> = 0.047, <em>p</em> = 0.026). Furthermore, non-drinkers and those with a drinking duration of less than 120 months or between 120–240 months showed higher 5-year PFS and OS rates than individuals with a drinking duration exceeding 240 months (<em>p</em> < 0.05). Similarly, non-drinkers and individuals consuming less than 50 g/day had higher 5-year PFS and OS rates compared to those consuming 50–100 g/day or more than 100 g/day (<em>p</em> < 0.05). Additionally, the 5-year PFS and OS rates were higher in the non-drinking and light drinking groups compared to the moderate and heavy drinking groups (<em>p</em> < 0.05). (3) A partial synergistic effect between smoking and alcohol drinking was observed in NPC. (4) Alcohol drinking emerged as an independent prognostic factor for NPC.</div></div><div><h3>Conclusion</h3><div>Alcohol drinking is a significant factor influencing the prognosis of nasopharyngeal carcinoma, with the adverse effects further amplified when combined with smoking.</div></div><div><h3>Level of evidence</h3><div>Level 2.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101534"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-19DOI: 10.1016/j.bjorl.2024.101532
Caroline da Silva Seidler, Marianne Yumi Nakai, Lucas Ribeiro Tenório, Daniela Serrano Marquezin, Renata Santos Bittencourt Silva, Marcelo Benedito Menezes, Antonio José Gonçalves
Objectives
To evaluate vocal, swallowing and respiratory rehabilitation of patients undergoing supracricoid laryngectomy; evaluate the impact of voice changes and global quality of life.
Methods
It is a prospective cohort study where voice, swallowing and respiratory rehabilitation where evaluated. Quality of life was assessed using EORTC QLQ-C30 and H&N35 questionnaires.
Results
31 patients were included in the study. 70.4% of patients were T3. In swallowing assessment, two patients (6.4%) were considered non-rehabilitated. Ten patients (32.2%) were considered partially rehabilitated and 19 (61.3%) fully rehabilitated. Sensitivity was abnormal at 74.2%. Penetration occurred in 58.1% of patients with 29% experiencing aspiration. In voice assessment, 19 (61.3%) patients were considered rehabilitated. 77.41% had a calculated voice handicap index considered abnormal. When assessing breathing, eight patients (25.8%) were considered non-rehabilitated. Disease-free survival was 87.1% in follow-up of 5.77 years. When subjected to specific exams and evaluations, only 38.7% were completely rehabilitated. When comparing results of EORTC-C30 and H&N35 questionnaires with the reference values, global score and domain scores are better on the patients of the study, as well as some of the symptoms.
Conclusion
Partial supracricoid laryngectomy remains an option in patients with laryngeal tumors, especially in the most advanced ones, with a survival rate around 90%. Quality of life is impacted after surgery, but with few symptoms.
{"title":"Rehabilitation after supracricoid partial laryngectomy: cohort study","authors":"Caroline da Silva Seidler, Marianne Yumi Nakai, Lucas Ribeiro Tenório, Daniela Serrano Marquezin, Renata Santos Bittencourt Silva, Marcelo Benedito Menezes, Antonio José Gonçalves","doi":"10.1016/j.bjorl.2024.101532","DOIUrl":"10.1016/j.bjorl.2024.101532","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate vocal, swallowing and respiratory rehabilitation of patients undergoing supracricoid laryngectomy; evaluate the impact of voice changes and global quality of life.</div></div><div><h3>Methods</h3><div>It is a prospective cohort study where voice, swallowing and respiratory rehabilitation where evaluated. Quality of life was assessed using EORTC QLQ-C30 and H&N35 questionnaires.</div></div><div><h3>Results</h3><div>31 patients were included in the study. 70.4% of patients were T3. In swallowing assessment, two patients (6.4%) were considered non-rehabilitated. Ten patients (32.2%) were considered partially rehabilitated and 19 (61.3%) fully rehabilitated. Sensitivity was abnormal at 74.2%. Penetration occurred in 58.1% of patients with 29% experiencing aspiration. In voice assessment, 19 (61.3%) patients were considered rehabilitated. 77.41% had a calculated voice handicap index considered abnormal. When assessing breathing, eight patients (25.8%) were considered non-rehabilitated. Disease-free survival was 87.1% in follow-up of 5.77 years. When subjected to specific exams and evaluations, only 38.7% were completely rehabilitated. When comparing results of EORTC-C30 and H&N35 questionnaires with the reference values, global score and domain scores are better on the patients of the study, as well as some of the symptoms.</div></div><div><h3>Conclusion</h3><div>Partial supracricoid laryngectomy remains an option in patients with laryngeal tumors, especially in the most advanced ones, with a survival rate around 90%. Quality of life is impacted after surgery, but with few symptoms.</div></div><div><h3>Level of evidence</h3><div>Level 3.<span><span><sup>1</sup></span></span></div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101532"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-19DOI: 10.1016/j.bjorl.2024.101531
Priscilla Campos , Solange O.R. Valle , Antônio José Ledo Alves da Cunha , Fábio Chigres Kuschnir , Dirceu Solé
Objective
To validate and assess the reproducibility of the ISAAC Written Allergic Rhinitis Questionnaire (WARQ) for children aged between 6 and 7 years by telephone contact.
Methods
Observational study through interviews with guardians of children aged 6–7 years using the ISAAC Allergic Rhinitis (AR) module questionnaire in three different phases separated by 2 weeks each: telephone interviews in the first and third contacts and face-to-face interviews, with the same guardian of telephone interviews, in the second contact. Reproducibility was estimated using the Kappa index and validation using the sensitivity and specificity coefficients.
Results
Data from 94 children (48 from the allergic rhinitis Control Group ‒ CG) were analyzed. Reproducibility showed perfect agreement (100%) for the question number 1 – Which refers to the symptoms of AR, ever: “Has your child ever had a problem with sneezing or a runny or a blocked nose when he/she did not have a cold or the flu?” and for the question number 2 – Which refers to current symptoms of AR: “In the past 12 months, has your child had a problem with sneezing or a runny or a blocked nose when he/she did not have a cold or the flu?” A strong agreement was also observed for the question number 3 (κ = 0.871) – it defines the presence of comorbidity of allergic rhinoconjuntivitis “In the past 12 months, has this nose problem been accompanied by itchy-watery eyes?” The validation showed high specificity (≥76.7%) and sensitivity (≥98%) for all questions, except for the ones related to seasonality and intensity of symptoms.
Conclusions
Our results showed that the ISAAC AR module questionnaire by telephone interviews has good reproducibility and high agreement with the clinical diagnosis of AR. It may be an appropriate alternative tool in epidemiological studies of childhood AR, especially in periods of social isolation, such as Coronavirus pandemic.
Level of evidence
Cohort Study. Level IV
目的通过电话联系，验证和评估针对6至7岁儿童的ISAAC过敏性鼻炎书面问卷（WARQ）的可重复性：通过对 6-7 岁儿童监护人的访谈进行观察研究，使用 ISAAC 过敏性鼻炎 (AR) 模块问卷，分三个不同阶段进行，每个阶段间隔 2 周：第一次和第三次联系时进行电话访谈，第二次联系时与电话访谈的同一监护人进行面对面访谈。再现性采用卡帕指数估算，验证性采用灵敏度和特异性系数估算：分析了 94 名儿童（48 名来自过敏性鼻炎对照组--CG）的数据。可重复性显示，在问题 1（指曾经出现过的 AR 症状）"您的孩子在没有伤风感冒的情况下，是否曾经出现过打喷嚏、流鼻涕或鼻塞的问题？第 3 个问题（κ = 0.871）也具有很高的一致性--它定义了是否存在过敏性鼻并发症："在过去 12 个月中，这种鼻部问题是否伴有眼睛发痒流泪？验证结果显示，除了与季节性和症状强度有关的问题外，所有问题的特异性（≥76.7%）和敏感性（≥98%）都很高：我们的研究结果表明，通过电话访问进行的 ISAAC AR 模块问卷与 AR 的临床诊断具有良好的重现性和高度一致性。在儿童 AR 的流行病学研究中，尤其是在冠状病毒大流行等社会隔离时期，它可能是一种合适的替代工具：证据等级：队列研究：
{"title":"Validation and reproducibility of the International Study of Asthma and Allergies in Childhood (ISAAC) Written Allergic Rhinitis Questionnaire for phone survey in children aged 6‒7 years","authors":"Priscilla Campos , Solange O.R. Valle , Antônio José Ledo Alves da Cunha , Fábio Chigres Kuschnir , Dirceu Solé","doi":"10.1016/j.bjorl.2024.101531","DOIUrl":"10.1016/j.bjorl.2024.101531","url":null,"abstract":"<div><h3>Objective</h3><div>To validate and assess the reproducibility of the ISAAC Written Allergic Rhinitis Questionnaire (WARQ) for children aged between 6 and 7 years by telephone contact.</div></div><div><h3>Methods</h3><div>Observational study through interviews with guardians of children aged 6–7 years using the ISAAC Allergic Rhinitis (AR) module questionnaire in three different phases separated by 2 weeks each: telephone interviews in the first and third contacts and face-to-face interviews, with the same guardian of telephone interviews, in the second contact. Reproducibility was estimated using the Kappa index and validation using the sensitivity and specificity coefficients.</div></div><div><h3>Results</h3><div>Data from 94 children (48 from the allergic rhinitis Control Group ‒ CG) were analyzed. Reproducibility showed perfect agreement (100%) for the question number 1 – Which refers to the symptoms of AR, ever: “Has your child ever had a problem with sneezing or a runny or a blocked nose when he/she did not have a cold or the flu?” and for the question number 2 – Which refers to current symptoms of AR: “In the past 12 months, has your child had a problem with sneezing or a runny or a blocked nose when he/she did not have a cold or the flu?” A strong agreement was also observed for the question number 3 (κ = 0.871) – it defines the presence of comorbidity of allergic rhinoconjuntivitis “In the past 12 months, has this nose problem been accompanied by itchy-watery eyes?” The validation showed high specificity (≥76.7%) and sensitivity (≥98%) for all questions, except for the ones related to seasonality and intensity of symptoms.</div></div><div><h3>Conclusions</h3><div>Our results showed that the ISAAC AR module questionnaire by telephone interviews has good reproducibility and high agreement with the clinical diagnosis of AR. It may be an appropriate alternative tool in epidemiological studies of childhood AR, especially in periods of social isolation, such as Coronavirus pandemic.</div></div><div><h3>Level of evidence</h3><div>Cohort Study. Level IV</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101531"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-19DOI: 10.1016/j.bjorl.2024.101533
Luis Lassaletta , Miryam Calvino , Isabel Sánchez-Cuadrado , Elena Muñoz , Javier Gavilán
Objectives
To compare Anatomy-Based Fitting (ABF) vs. Default Fitting (DF) in terms of music perception and music enjoyment in CI users.
Methods
CI users ≥ 18 years implanted with a Synchrony ST Flex28 (MEDEL) with at least 12 months of experience with either ABF or DF, with good speech tests outcomes (≥ 65% disyllables) were enrolled. Music tasks were assessed with “Discovery” level of Meludia online interactive music tool, which includes Rhythm (beat count), Spatialization (differentiating between lower and higher notes), Stable/unstable (perception of stability or instability), Melody (ascendant or descendant), and Density (presence of one or multiple simultaneous sounds). Each task consists of five levels of difficulty. Participants were allowed a maximum of 4 attempts to complete a level. The Music-Related Quality of Life (MuRQoL) and the Munich Music (MUMU) questionnaires evaluated music background.
Results
Twenty CI users took part: 10 using ABF and 10 DF. There were no significant differences in age at implantation (53.2 ± 15.0 vs. 53.8 ± 14.5y), time since surgery (1.8 ± 0.5 vs. 2.4 ± 1.5y), or the percentage of disyllables in silence (68.0 ± 8.0 vs. 77.3 ± 11.5%) between groups. Regarding Meludia scores, differences were observed between both groups in Density: ABF had better mean scores when completing the level in only one attempt (8.7 ± 2.5 vs. 4.6 ± 3.1, p = 0.016) and required fewer restarts to complete the five levels (6.6 ± 1.6 vs. 9.3 ± 2.3; p = 0.009). Furthermore, the fifth level of Density was successfully completed by 60% of patients with ABF, while none of the patients with DF achieved this (p = 0.003). The scores obtained in MuRQoL were similar between ABF and DF groups. In a similar way, the MUMU showed no differences in terms of frequency and music importance.
Conclusions
ABF demonstrates specific advantages in certain musical tasks, specifically in processing multiple sounds simultaneously. Further studies are necessary to explore additional benefits of ABF in musical skills in CI users. NCT05319678.
Level of evidence
Level 3.
目的比较基于解剖的装配（ABF）与默认装配（DF）对 CI 用户音乐感知和音乐享受的影响：方法：招募年龄≥ 18 岁、植入 Synchrony ST Flex28 (MEDEL)、使用 ABF 或 DF 至少 12 个月、语音测试结果良好（双音节率≥ 65%）的 CI 用户。音乐任务使用 Meludia 在线互动音乐工具的 "发现 "级别进行评估，包括节奏（节拍计数）、空间化（区分低音和高音）、稳定/不稳定（感知稳定或不稳定）、旋律（升调或降调）和密度（同时出现一个或多个声音）。每项任务由五个难度级别组成。参与者最多可尝试 4 次完成一个级别。音乐相关生活质量（MuRQoL）和慕尼黑音乐（MUMU）问卷对音乐背景进行了评估：结果：20 名 CI 用户参加了调查：10 人使用 ABF，10 人使用 DF。植入时的年龄（53.2 ± 15.0 岁 vs. 53.8 ± 14.5 岁）、手术后的时间（1.8 ± 0.5 岁 vs. 2.4 ± 1.5 岁）或静音时的双音节百分比（68.0 ± 8.0% vs. 77.3 ± 11.5%）在各组间无明显差异。关于 Meludia 分数，两组之间在密度上存在差异：ABF 组在只尝试一次就完成该级别时平均得分更高（8.7 ± 2.5 vs. 4.6 ± 3.1，p = 0.016），在完成五个级别时需要重新开始的次数更少（6.6 ± 1.6 vs. 9.3 ± 2.3；p = 0.009）。此外，60% 的 ABF 患者成功完成了第五级密度，而 DF 患者则无一成功完成（p = 0.003）。ABF 组和 DF 组的 MuRQoL 得分相似。同样，MUMU 在频率和音乐重要性方面也没有显示出差异：结论：ABF 在某些音乐任务中，尤其是在同时处理多种声音方面表现出了特殊的优势。有必要开展进一步研究，探索 ABF 对 CI 用户音乐技能的其他益处。NCT05319678.证据等级：3级。
{"title":"Can anatomy-based fitting improve musical perception in adult cochlear implant users?","authors":"Luis Lassaletta , Miryam Calvino , Isabel Sánchez-Cuadrado , Elena Muñoz , Javier Gavilán","doi":"10.1016/j.bjorl.2024.101533","DOIUrl":"10.1016/j.bjorl.2024.101533","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare Anatomy-Based Fitting (ABF) vs. Default Fitting (DF) in terms of music perception and music enjoyment in CI users.</div></div><div><h3>Methods</h3><div>CI users ≥ 18 years implanted with a Synchrony ST Flex28 (MEDEL) with at least 12 months of experience with either ABF or DF, with good speech tests outcomes (≥ 65% disyllables) were enrolled. Music tasks were assessed with “Discovery” level of Meludia online interactive music tool, which includes Rhythm (beat count), Spatialization (differentiating between lower and higher notes), Stable/unstable (perception of stability or instability), Melody (ascendant or descendant), and Density (presence of one or multiple simultaneous sounds). Each task consists of five levels of difficulty. Participants were allowed a maximum of 4 attempts to complete a level. The Music-Related Quality of Life (MuRQoL) and the Munich Music (MUMU) questionnaires evaluated music background.</div></div><div><h3>Results</h3><div>Twenty CI users took part: 10 using ABF and 10 DF. There were no significant differences in age at implantation (53.2 ± 15.0 vs. 53.8 ± 14.5y), time since surgery (1.8 ± 0.5 vs. 2.4 ± 1.5y), or the percentage of disyllables in silence (68.0 ± 8.0 vs. 77.3 ± 11.5%) between groups. Regarding Meludia scores, differences were observed between both groups in Density: ABF had better mean scores when completing the level in only one attempt (8.7 ± 2.5 vs. 4.6 ± 3.1, <em>p</em> = 0.016) and required fewer restarts to complete the five levels (6.6 ± 1.6 vs. 9.3 ± 2.3; <em>p</em> = 0.009). Furthermore, the fifth level of Density was successfully completed by 60% of patients with ABF, while none of the patients with DF achieved this (<em>p</em> = 0.003). The scores obtained in MuRQoL were similar between ABF and DF groups. In a similar way, the MUMU showed no differences in terms of frequency and music importance.</div></div><div><h3>Conclusions</h3><div>ABF demonstrates specific advantages in certain musical tasks, specifically in processing multiple sounds simultaneously. Further studies are necessary to explore additional benefits of ABF in musical skills in CI users. NCT05319678.</div></div><div><h3>Level of evidence</h3><div>Level 3.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101533"},"PeriodicalIF":1.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-18DOI: 10.1016/j.bjorl.2024.101535
Changding He , Yu Heng , Xiaoke Zhu, Jian Zhou, Lei Tao
Objective
To identify risk factors for Lymph Node Metastasis (LNM) in pT3-4 Laryngeal Squamous Cell Carcinoma (LSCC) patients with negative margins, and develop a nomogram to predict LNM risk.
Methods
872 patients were divided into training (2010–2014) and validation (2015–2016) cohorts. Univariate and multivariate analyses identified LNM risk factors. A nomogram incorporating significant factors was developed in the training cohort.
Results
Smoking history, maximal tumor diameter ≥3.0 cm, depth of tumor invasion >1.0 cm, and supraglottic tumor location were significantly associated with LNM on multivariate analysis. A predictive nomogram incorporating these factors showed good discrimination (C-index > 0.7) in both cohorts. Patients were stratified into low, moderate and high-risk subgroups based on total risk scores.
Conclusions
A LNM risk prediction model and risk grouping system was established, which may aid treatment selection for pT3-4 LSCC patients. The model and algorithm could help optimize neck management for this high-risk patient population.
{"title":"Development and internal validation of risk stratification tool for lymph node metastasis in pT3-4 laryngeal squamous cell carcinoma patients","authors":"Changding He , Yu Heng , Xiaoke Zhu, Jian Zhou, Lei Tao","doi":"10.1016/j.bjorl.2024.101535","DOIUrl":"10.1016/j.bjorl.2024.101535","url":null,"abstract":"<div><h3>Objective</h3><div>To identify risk factors for Lymph Node Metastasis (LNM) in pT3-4 Laryngeal Squamous Cell Carcinoma (LSCC) patients with negative margins, and develop a nomogram to predict LNM risk.</div></div><div><h3>Methods</h3><div>872 patients were divided into training (2010–2014) and validation (2015–2016) cohorts. Univariate and multivariate analyses identified LNM risk factors. A nomogram incorporating significant factors was developed in the training cohort.</div></div><div><h3>Results</h3><div>Smoking history, maximal tumor diameter ≥3.0 cm, depth of tumor invasion >1.0 cm, and supraglottic tumor location were significantly associated with LNM on multivariate analysis. A predictive nomogram incorporating these factors showed good discrimination (C-index > 0.7) in both cohorts. Patients were stratified into low, moderate and high-risk subgroups based on total risk scores.</div></div><div><h3>Conclusions</h3><div>A LNM risk prediction model and risk grouping system was established, which may aid treatment selection for pT3-4 LSCC patients. The model and algorithm could help optimize neck management for this high-risk patient population.</div></div><div><h3>Level of evidence</h3><div>2.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101535"},"PeriodicalIF":1.7,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-05DOI: 10.1016/j.bjorl.2024.101520
Li Zhang , Zhilin Li , Jing Wang , Chen Wang , Shuxin Wen
Objective
To understand the characteristics of cervical lymph node metastasis in Oropharyngeal Squamous Cell Carcinoma (OPSCC) patients, explore the risk factors for lymph node metastasis, and its impact on prognosis.
Methods
Retrospective cohort study. Statistical analysis of the relationship between various clinicopathological factors and lymph node involvement, as well as the independent risk factors affecting lymph node metastasis and their impact on prognosis.
Results
The cervical lymph node metastasis rate in this group was 89.2%, with the palatine tonsils and base of the tongue more prone to cervical lymph node metastasis (p = 0.007); lower pathological differentiation of OPSCC was more likely to develop cervical lymph node metastasis (p = 0.017). The P16 protein positive rate in this group was 58.8%. P16 protein expression did not affect the incidence rate of cervical lymph node metastasis in OPSCC (p = 1.000) but influenced the risk of multiple lymph node metastases (p = 0.011) and was a risk factor affecting the prognosis of OPSCC (p = 0.003). However, the lymph node metastasis status did not affect the survival time of OPSCC patients.
Conclusion
In the Shanxi region of China, HPV-related OPSCC accounts for a higher proportion; OPSCC has a high rate of cervical lymph node metastasis, but lymph node metastasis does not significantly increase the mortality risk of OPSCC patients, which may be related to the unique characteristics of HPV-related OPSCC.
{"title":"Risk factors for cervical lymph node metastasis in oropharyngeal cancer and its impact on prognosis","authors":"Li Zhang , Zhilin Li , Jing Wang , Chen Wang , Shuxin Wen","doi":"10.1016/j.bjorl.2024.101520","DOIUrl":"10.1016/j.bjorl.2024.101520","url":null,"abstract":"<div><h3>Objective</h3><div>To understand the characteristics of cervical lymph node metastasis in Oropharyngeal Squamous Cell Carcinoma (OPSCC) patients, explore the risk factors for lymph node metastasis, and its impact on prognosis.</div></div><div><h3>Methods</h3><div>Retrospective cohort study. Statistical analysis of the relationship between various clinicopathological factors and lymph node involvement, as well as the independent risk factors affecting lymph node metastasis and their impact on prognosis.</div></div><div><h3>Results</h3><div>The cervical lymph node metastasis rate in this group was 89.2%, with the palatine tonsils and base of the tongue more prone to cervical lymph node metastasis (<em>p</em> <!-->=<!--> <!-->0.007); lower pathological differentiation of OPSCC was more likely to develop cervical lymph node metastasis (<em>p</em> <!-->=<!--> <!-->0.017). The P16 protein positive rate in this group was 58.8%. P16 protein expression did not affect the incidence rate of cervical lymph node metastasis in OPSCC (<em>p</em> <!-->=<!--> <!-->1.000) but influenced the risk of multiple lymph node metastases (<em>p</em> <!-->=<!--> <!-->0.011) and was a risk factor affecting the prognosis of OPSCC (<em>p</em> <!-->=<!--> <!-->0.003). However, the lymph node metastasis status did not affect the survival time of OPSCC patients.</div></div><div><h3>Conclusion</h3><div>In the Shanxi region of China, HPV-related OPSCC accounts for a higher proportion; OPSCC has a high rate of cervical lymph node metastasis, but lymph node metastasis does not significantly increase the mortality risk of OPSCC patients, which may be related to the unique characteristics of HPV-related OPSCC.</div></div><div><h3>Level of Evidence Ⅳ</h3><div>Retrospective cohort study.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101520"},"PeriodicalIF":1.7,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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