Revue Francaise d Allergologie最新文献_第5页

Drug reaction with eosinophilia and systemic symptoms syndrome to non-steroidal anti-inflammatory drugs: A report of case series and literature review 非甾体抗炎药伴嗜酸性粒细胞增多和全身症状综合征的药物反应：病例系列报告及文献复习

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-07-01 Epub Date: 2025-03-20 DOI: 10.1016/j.reval.2024.104221

M. Daldoul , O. Charfi , F. Zgolli , K. Ferchichi , G. Lakhoua , S. Kastalli , R. Daghfous , A. Zaiem , I. Aouinti , S. El Aidli

Introduction

DRESS syndrome is a rare, severe cutaneous adverse reaction that has been exceptionally described with NSAIDs. The objective of our study was to investigate the clinical, paraclinical, and epidemiological characteristics of DRESS syndrome associated with NSAIDs and to identify the implicated molecules.

Patients and methods

A retrospective descriptive study that included all cases of DRESS syndrome occurring with NSAIDs and reported over a 10-year period. Records were analyzed according to the RegiSCAR criteria for the diagnosis of DRESS and the French imputability method.

Results

We included 7 cases, with a female-to-male ratio of 1.33. The age of patients ranged from 18 to 75 years, with a mean of 55 years. The time to onset varied from 4 to 30 days, with a mean of 12 days. A fever equal to or greater than 38.5 °C was observed in 5 patients. All patients had skin involvement, mainly in the form of a maculopapular rash in 6 cases and erythroderma with glossitis in one case. Hypereosinophilia was found in 4 out of 7 patients. Hepatic involvement was observed in 4 patients, associated with renal involvement in 2 cases. One patient had isolated renal involvement. The NSAIDs implicated in DRESS syndrome in our patients were diclofenac, piroxicam, ketoprofen, and celecoxib.

Conclusion

Our study highlights the rarity and potential severity of DRESS syndrome associated with NSAIDs, due to systemic involvement. Clinicians should be vigilant about the possibility of DRESS syndrome with NSAID use, in order to promptly discontinue the implicated drug and ensure rapid management.

dress综合征是一种罕见的、严重的皮肤不良反应，在非甾体抗炎药中有特别的描述。本研究的目的是调查与非甾体抗炎药相关的DRESS综合征的临床、临床旁和流行病学特征，并确定相关分子。患者和方法一项回顾性描述性研究，纳入了所有使用非甾体抗炎药发生的DRESS综合征病例，报告时间超过10年。根据RegiSCAR诊断DRESS的标准和法式归责法对记录进行分析。结果纳入病例7例，男女比1.33。患者年龄从18岁到75岁不等，平均55岁。发病时间从4天到30天不等，平均12天。5例患者发热大于或等于38.5℃。所有患者均有皮肤受累，主要表现为6例黄斑丘疹，1例伴有舌炎的红皮病。7例患者中有4例出现嗜酸性粒细胞增多。4例患者肝脏受累，2例合并肾脏受累。1例患者有孤立的肾脏受累。在我们的患者中，与DRESS综合征相关的非甾体抗炎药有双氯芬酸、吡罗西康、酮洛芬和塞来昔布。结论：我们的研究强调了与非甾体抗炎药相关的DRESS综合征的罕见性和潜在严重性，这是由于全身受累。临床医生应警惕使用非甾体抗炎药引起DRESS综合征的可能性，以便及时停用相关药物并确保快速管理。

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引用次数: 0

The effect of biological agent use on symptoms in patients diagnosed with NSAID-Exacerbated Respiratory Disease (NERD) 生物制剂对非甾体抗炎药加重呼吸道疾病（NERD）患者症状的影响

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-07-01 Epub Date: 2025-03-20 DOI: 10.1016/j.reval.2024.104219

H. Çelik Tuğlu, K. Aksu, O. Telli, F. Dindar Çelik, M. Yağdıran, Ö. Akkale, G. Köycü Buhari, S.N. Bahçecioğlu, G.T. Vural Solak

Introduction

In recent years, biological approaches targeting Type 2 cytokines have emerged as potential treatment options in NSAID-Exacerbated Respiratory Disease (NERD) patients. In this study, we aimed to evaluate the clinical efficacy of omalizumab and mepolizumab in NERD patients with severe asthma via nasal and respiratory symptoms, pulmonary functions and exacerbation status.

Methods

The study was conducted retrospectively in adults with NERD who were initiated on omalizumab and mepolizumab and had been treated with a biologic agent for at least 1 year. Data on lung function test results, eosinophil counts, asthma exacerbation rates, asthma control levels, and Sino-Nasal Outcome Test-22 scores before starting the biological agent were compared with data obtained 1 year after starting the biological treatment.

Results

The study included data from 18 NERD patients, 10 of whom received omalizumab and 8 of whom received mepolizumab. In the NERD group receiving omalizumab, statistically significant changes were observed in terms of clinical improvement in FEV1 values, mean eosinophil counts, annual exacerbation rates, asthma control and SNOT-22 scores after biologic treatment. In patients receiving mepolizumab, significant decreases were found in mean eosinophil counts, annual exacerbation rates and SNOT-22 scores after biologic treatment compared to pre-treatment. Daily oral corticosteroid requirements were significantly reduced in patients receiving both omalizumab and mepolizumab.

Conclusion

In conclusion, the present study results reveal that both omalizumab and mepolizumab treatments are effective in controlling nasal symptoms, reducing the number of asthma exacerbations, and reducing the need for low-dose maintenance steroids in severe asthmatics with NERD.

近年来，针对2型细胞因子的生物学方法已成为nsaid加重呼吸系统疾病（NERD）患者的潜在治疗选择。在本研究中，我们旨在通过鼻腔和呼吸道症状、肺功能和加重状态来评估omalizumab和mepolizumab在NERD重症哮喘患者中的临床疗效。方法本研究回顾性研究了成人NERD患者，他们开始使用omalizumab和mepolizumab，并使用生物制剂治疗至少1年。将开始生物治疗前的肺功能检查结果、嗜酸性粒细胞计数、哮喘加重率、哮喘控制水平和Sino-Nasal Outcome test -22评分与开始生物治疗后1年的数据进行比较。该研究纳入了18例NERD患者的数据，其中10例接受了omalizumab治疗，8例接受了mepolizumab治疗。在接受omalizumab治疗的NERD组中，在生物治疗后FEV1值、平均嗜酸性粒细胞计数、年加重率、哮喘控制和SNOT-22评分的临床改善方面观察到具有统计学意义的变化。在接受mepolizumab治疗的患者中，与治疗前相比，生物治疗后的平均嗜酸性粒细胞计数、年加重率和SNOT-22评分显著降低。同时接受omalizumab和mepolizumab治疗的患者每日口服皮质类固醇需用量显著降低。结论本研究结果表明，omalizumab和mepolizumab治疗均可有效控制伴有NERD的严重哮喘患者的鼻腔症状，减少哮喘发作次数，减少低剂量维持性类固醇的需求。

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引用次数: 0

Évolution fatale liée à l’abus de dermocorticoïdes chez un adulte 成人皮肤皮质激素滥用的致命进化

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-07-01 Epub Date: 2025-03-20 DOI: 10.1016/j.reval.2024.104220

S. Ait Oussous , I. Lakhal , M. Hamaichat , I. Damoune , F. Ajdi , R. Chakiri

Introduction

Topical corticosteroids are widely used in the management of chronic inflammatory dermatoses with impaired skin barrier, such as atopic dermatitis and psoriasis. However, their long-term use can lead to systemic effects due to percutaneous absorption. We report a case illustrating the severity of complications associated with excessive use of these medications.

Observation

A 32-year-old woman had been under follow-up for a dermatologic condition with a relapsing-remitting course, evolving since the age of 3. She was initially treated with a high-potency topical corticosteroid, which led to good improvement. However, she continued self-administering topical corticosteroids for 22 years. She presented with erythroderma characterized by desquamation, edema, and erosions in some areas. The clinical presentation, along with excessive use of betamethasone, suggested iatrogenic Cushing's syndrome. Laboratory tests revealed corticotropic adrenal insufficiency. A skin biopsy confirmed the diagnosis of atopic dermatitis. Management included treatment of fungal, infectious, and metabolic complications. Hydrocortisone was initiated, and after education, topical corticosteroids were replaced with topical tacrolimus. The patient was lost to follow-up and succumbed to adrenal insufficiency one month later.

Conclusion

This case highlights the severity of iatrogenic complications secondary to misuse of topical corticosteroids and underscores the need for proper therapeutic education and adequate follow-up.

外用皮质类固醇广泛用于治疗皮肤屏障受损的慢性炎症性皮肤病，如特应性皮炎和牛皮癣。然而，由于经皮吸收，长期使用可导致全身效应。我们报告一个病例说明并发症的严重程度与过度使用这些药物。观察：一名32岁女性，自3岁起因皮肤疾病复发缓解而接受随访。她最初接受了一种高效的局部皮质类固醇治疗，这导致了良好的改善。然而，她继续自我使用局部皮质类固醇22年。她表现为红皮病，特征为脱屑、水肿和部分部位糜烂。临床表现，加上过量使用倍他米松，提示医源性库欣综合征。实验室检查显示促肾上腺皮质功能不全。皮肤活检证实了特应性皮炎的诊断。治疗包括真菌、感染和代谢并发症的治疗。开始使用氢化可的松，教育后，局部皮质类固醇被局部他克莫司取代。患者失访，1个月后死于肾上腺功能不全。结论本病例突出了外用糖皮质激素引起的医源性并发症的严重性，强调了适当的治疗教育和充分的随访的必要性。

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引用次数: 0

La faute au thon ou au chef ? Enquêter sur une cause inhabituelle d’anaphylaxie 是金枪鱼的错还是厨师的错？调查过敏的不寻常原因

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-05-01 Epub Date: 2025-03-19 DOI: 10.1016/j.reval.2024.104224

J. Nogueira Oliveira , J. Carvalho Queirós , R. Calejo , R. Teixeira , R. Gomes , L. Marques , D. Pinto , A.R. Araújo , F. Teixeira

引用次数: 0

Nouvelles sources protéiques et nouveaux allergènes : sensibilisation de novo et réactivité croisée 新的蛋白质来源和新的过敏原：新认识和交叉反应

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-05-01 Epub Date: 2025-02-15 DOI: 10.1016/j.reval.2024.104203

S. Hazebrouck, Y. Awad, H. Bernard

In response to climate change and new dietary trends, the sustainable production of novel protein sources, as alternative to those of animal origin, and the use of novel food ingredients and complements are increasing. In this context, the allergenic risk of these novel foods needs to be assessed. Current guidance for allergenicity risk assessment relies on a weight-of-evidence approach to determine the risk of de novo sensitization and the risk of cross-reactivity to novel food antigens in patients already sensitized to known allergens. Nevertheless, the evolution of our dietary habits will inevitably increase the frequency of certain food allergies, as already observed for insect or legume proteins. Therefore, alongside the development of in silico and in vitro experimental models to better apprehend the allergenic potential of foods, anaphylaxis registries remain a critical tool for monitoring and warning of emerging allergens.

为了应对气候变化和新的饮食趋势，新型蛋白质来源的可持续生产，作为动物源性蛋白质的替代品，以及新型食品成分和补充剂的使用正在增加。在这种情况下，需要评估这些新型食品的致敏风险。目前的致敏性风险评估指南依赖于证据权重法来确定已经对已知过敏原致敏的患者重新致敏的风险和对新型食物抗原交叉反应的风险。然而，我们饮食习惯的演变将不可避免地增加某些食物过敏的频率，正如已经观察到的昆虫或豆类蛋白质。因此，随着计算机和体外实验模型的发展，以更好地了解食物的致敏潜力，过敏反应登记仍然是监测和警告新出现的过敏原的重要工具。

引用次数: 0

Corrigendum à l’article « Enfant présentant une allergie alimentaire en crèche : quelle est la place du Projet d’Accueil Individualisé ? Quels ressentis pour le personnel ? » [Rev. Fr. Allergol. 64 (6) (2024) 104138] “日托中心食物过敏儿童：个性化家庭项目的位置在哪里？”对员工有什么感觉？[Rev. Fr. Allergol. 64 (6) (2024) 104138]

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-05-01 Epub Date: 2025-03-19 DOI: 10.1016/j.reval.2025.104250

A. Thong Buisson , M.-C. Leoni

引用次数: 0

Healthy lifestyle in 0–6-year-old children's parents with food and non-food allergy 0 - 6岁食物和非食物过敏儿童父母的健康生活方式

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-05-01 Epub Date: 2025-03-19 DOI: 10.1016/j.reval.2024.104205

C. Cakici , S. Şeker , A.D. Karaman

Background

Health lifestyle behaviors of parents with food and non-food allergic children are not well understood.

Objective

This study aimed to examine the difference between healthy lifestyle behaviors of parents of 0–6-year-old children with food allergies and non-food allergies.

Methods

This analytical cross-sectional study was conducted with the parents of 153 allergic children admitted to Aydin Obstetrics, Gynecology and Child Diseases Hospital between October 2022 and March 2023. “Personal Information Form” and “Health Promoting Lifestyle Profile II” were used to collect data and analyzed using Mann-Whitney-U, chi-square test, Student-t test.

Results

The mean total score of the Health-Promoting Lifestyle Profile II was 135.4 ± 19.5 for parents of food allergic children and 139.1 ± 24.1 for parents of non-food allergic children. There was no significant difference between the total scores of the Health-Promoting Lifestyle Profile II between the parents of allergic children (t = −1.048, P > 0.05). While there was no significant difference in terms of the other subscales of the questionnaire, the physical activity subscale mean score of parents of children with non-food allergies was higher than those with food allergies (t = −1.986, P = 0.049). Child's age, parental education level, and family history were found to be significant factors in the development of food allergies (P < 0.05).

Conclusion

While there was no difference in the healthy lifestyle behaviors of parents with food allergic and non-food allergic children, it was concluded that parents with non-food allergic children had better lifestyles only for the “Physical Activity” subscale. It may be recommended that healthcare professionals should give importance to this issue to improve the healthy lifestyle of individuals in vulnerable groups.

食物过敏和非食物过敏儿童的父母的健康生活方式行为尚不清楚。目的探讨0 ~ 6岁食物过敏与非食物过敏患儿父母健康生活方式行为的差异。方法对2022年10月至2023年3月在艾丁妇产儿科医院收治的153例过敏儿童的家长进行分析性横断面研究。采用《个人信息表》和《健康促进生活方式资料II》收集资料，采用Mann-Whitney-U、卡方检验、Student-t检验进行分析。结果食物过敏儿童父母的健康促进生活方式ⅱ平均总分为135.4±19.5分，非食物过敏儿童父母的健康促进生活方式ⅱ平均总分为139.1±24.1分。过敏儿童父母在促进健康生活方式量表II总分上的差异无统计学意义(t = - 1.048, P >；0.05)。问卷其他各分量表间差异无统计学意义，但非食物过敏儿童家长的体力活动分量表平均得分高于食物过敏儿童家长（t = - 1.986, P = 0.049）。儿童年龄、父母受教育程度和家族史是食物过敏发生的重要因素(P <；0.05)。结论食物过敏儿童父母的健康生活方式行为与非食物过敏儿童父母的健康生活方式行为无显著差异，但非食物过敏儿童父母的健康生活方式仅在“身体活动”分量表上表现更好。建议保健专业人员重视这一问题，以改善弱势群体个人的健康生活方式。

{"title":"Healthy lifestyle in 0–6-year-old children's parents with food and non-food allergy","authors":"C. Cakici , S. Şeker , A.D. Karaman","doi":"10.1016/j.reval.2024.104205","DOIUrl":"10.1016/j.reval.2024.104205","url":null,"abstract":"<div><h3>Background</h3><div>Health lifestyle behaviors of parents with food and non-food allergic children are not well understood.</div></div><div><h3>Objective</h3><div>This study aimed to examine the difference between healthy lifestyle behaviors of parents of 0–6-year-old children with food allergies and non-food allergies.</div></div><div><h3>Methods</h3><div>This analytical cross-sectional study was conducted with the parents of 153 allergic children admitted to Aydin Obstetrics, Gynecology and Child Diseases Hospital between October 2022 and March 2023. “Personal Information Form” and “Health Promoting Lifestyle Profile II” were used to collect data and analyzed using Mann-Whitney-U, chi-square test, Student-<em>t</em> test.</div></div><div><h3>Results</h3><div>The mean total score of the Health-Promoting Lifestyle Profile II was 135.4±19.5 for parents of food allergic children and 139.1±24.1 for parents of non-food allergic children. There was no significant difference between the total scores of the Health-Promoting Lifestyle Profile II between the parents of allergic children (<em>t</em>  >0.05). While there was no significant difference in terms of the other subscales of the questionnaire, the physical activity subscale mean score of parents of children with non-food allergies was higher than those with food allergies (<em>t</em>  =0.049). Child's age, parental education level, and family history were found to be significant factors in the development of food allergies (<em>P</em>  <!-->0.05).</div></div><div><h3>Conclusion</h3><div>While there was no difference in the healthy lifestyle behaviors of parents with food allergic and non-food allergic children, it was concluded that parents with non-food allergic children had better lifestyles only for the “Physical Activity” subscale. It may be recommended that healthcare professionals should give importance to this issue to improve the healthy lifestyle of individuals in vulnerable groups.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 3","pages":"Article 104205"},"PeriodicalIF":0.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ex vivo and in vivo cross-reactivity between major and minor allergens from cow's milk: A study in Balb/c mouse model 牛奶中主要和次要过敏原的体内外交叉反应：Balb/c小鼠模型的研究

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-05-01 Epub Date: 2025-03-19 DOI: 10.1016/j.reval.2025.104251

H. Negaoui , H. Grar , H. Kaddouri , O. Kheroua , D. Saïdi , S. Addou

Study objective

It is well known that proteins that belong to the same family are often associated with frequent cross-reactivities. To the best of our knowledge, this is the first study evaluating the cross-reactivity between bovine lactoferrin (bLf) and the two major bovine milk allergens, β-lactoglobulin (β-Lg) and α-lactalbumin (α-La).

Materials and methods

Five-to six-week-old female Balb/c mice were randomly allocated to three groups (n = 14 per group) as follows: control group (unsensitized mice), β-lactoglobulin-sensitized group and α-lactalbumin-sensitized group. Mice were sensitized by intraperitoneal injection of 10 μg of allergen conjugated with aluminum hydroxide. Cross-reactivity was tested in vitro using an enzyme-linked immunosorbent assay, ex vivo by measuring electrophysiological parameters [short-current circuit (Isc) and tissue conductance (G)] in an Ussing chamber system and finally in vivo after an intraperitoneal challenge with bLf. Plasma histamine levels were also measured.

Results

bLf was found to significantly cross-react with either anti β-lg or anti α-La IgG with different intensities. Notably, the anti α-La IgG was more cross-reactive (P < 0.001). In Ussing chamber, the ex vivo exposure of intestinal segment of the two-sensitized groups to bLf induced a marked increase in Isc values (P < 0.05 and P < 0.006 respectively). However, the tissue conductance was increased only with the jejunal fragments of α-La-sensitized mice (P < 0.05). bLf cross-reactivity was also evidenced clinically by the appearance of clinical symptoms, as well as a significant increase in plasma histamine levels (P < 0.001).

Conclusion

bLf exhibits a strong allergenic potential and a high degree of homology, especially with α-La.

研究目的众所周知，属于同一家族的蛋白质通常与频繁的交叉反应有关。据我们所知，这是首次评估牛乳铁蛋白（bLf）与两种主要的牛奶过敏原β-乳球蛋白（β-Lg）和α-乳白蛋白（α-La）之间的交叉反应性的研究。材料与方法5 ~ 6周龄雌性Balb/c小鼠随机分为3组，每组14只，分别为对照组（未致敏小鼠）、β-乳球蛋白致敏组和α-乳蛋白致敏组。小鼠腹腔注射氢氧化铝偶联变应原10 μg致敏。在体外用酶联免疫吸附法测试交叉反应性，在体外用Ussing室系统测量电生理参数[短路（Isc）和组织电导(G)]，最后在体内用bLf腹腔注射后测试交叉反应性。同时还测量了血浆组胺水平。结果blf与抗β-lg和抗α-La IgG均有不同强度的交叉反应。值得注意的是，抗α-La IgG具有更强的交叉反应性(P <；0.001)。在Ussing实验室内，两致敏组肠段离体暴露于bLf诱导Isc值显著升高(P <；0.05和P <；0.006分别)。然而，α- la致敏小鼠的空肠碎片只增加了组织电导(P <；0.05)。临床症状的出现以及血浆组胺水平的显著升高也证明了bLf的交叉反应性(P <；0.001)。结论blf具有较强的致敏性，且与α-La具有高度的同源性。

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引用次数: 0

Yellow mealworm (Tenebrio molitor): A rare cause of chronic urticaria 黄粉虫（tenbrio molitor）：引起慢性荨麻疹的罕见原因

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-05-01 Epub Date: 2025-03-20 DOI: 10.1016/j.reval.2025.104255

D. Tekcan, I. Kulhas Celik, H. Artac

This report presents a unique case of chronic urticaria (CU) caused by a food allergy to mealworm. A 10-year-old boy experienced daily itchy urticarial rashes for three months, accompanied by swelling, especially in the morning. Despite high-dose second-generation antihistamines, montelukast, a hypoallergenic diet, and intermittent steroids, symptoms persisted. Routine investigations, including hemogram, thyroid function tests, and autoantibodies, were normal. Total IgE level was elevated (715 kU/L), but skin prick tests showed no sensitivities. Component-resolved diagnosis revealed a reaction to yellow mealworm (Tenebrio molitor, 0.53 kUA/L). Investigation uncovered daily bread consumption prepared from flour stored in non-heat-resistant sacks, where mealworms proliferated. Symptom resolution followed dietary elimination of contaminated flour, enabling treatment tapering. Tenebrio molitor thrives in high-temperature storage and is increasingly used as a protein source. Cross-reactivity with shrimp allergens is documented. This case highlights the role of environmental factors in CU and the utility of component-resolved diagnostics. Identifying yellow mealworm as a rare CU cause emphasizes the importance of comprehensive evaluation in persistent cases.

本报告提出了一个独特的慢性荨麻疹（CU）引起的食物过敏粉虫。一个10岁的男孩经历了三个月每天发痒的荨麻疹，并伴有肿胀，特别是在早上。尽管使用大剂量第二代抗组胺药、孟鲁司特、低过敏性饮食和间歇性类固醇，症状仍持续存在。常规检查包括血象、甲状腺功能检查和自身抗体均正常。总IgE水平升高（715 kU/L），但皮肤点刺试验未见敏感性。成分分辨诊断显示对黄粉虫（tenbrio molitor, 0.53 kUA/L）有反应。调查发现，人们每天食用的面包是由储存在不耐热袋子里的面粉制成的，在那里粉虫大量繁殖。在饮食中消除受污染的面粉后，症状得到解决，使治疗逐渐减少。黄粉虫在高温储存中茁壮成长，并越来越多地用作蛋白质来源。与虾过敏原的交叉反应是有记录的。这个案例强调了环境因素在CU中的作用以及组件解析诊断的效用。确定黄粉虫是一种罕见的CU病因，强调了对持续病例进行综合评估的重要性。

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引用次数: 0

Prise en charge des allergies professionnelles dans les services de prévention en santé au travail dans le département des Bouches-du-Rhône : enquête de satisfaction auprès des médecins du travail et proposition d’un projet innovant 在Bouches-du- Rhone省的职业健康预防服务中处理职业过敏问题：对职业医生的满意度进行调查，并提出一个创新项目

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2025-05-01 Epub Date: 2025-03-20 DOI: 10.1016/j.reval.2025.104539

M. MENDIL

Aim of the study

To study the preventive management of employees exposed to the risk of occupational allergy and occupational physicians’ satisfaction in the Bouches-du-Rhône department. The secondary objective was to study occupational physicians’ interest in an innovative project to set up an occupational allergy unit within the occupational health prevention department.

Patients and methods

Descriptive, cross-sectional epidemiological study including occupational physicians working in an occupational health prevention service in the Bouches-du-Rhône who responded to the questionnaire.

Results

According to the 50 occupational physicians who took part in the study, the preventive management of occupational allergies in their department was judged to be in need of improvement (88%, i.e. 44 of occupational physicians). Primary prevention (n = 37 or 74%) is most concerned along with secondary prevention (n = 33 or 66%). Tertiary prevention was considered to be improvable to a lesser extent (n = 24 or 48%). The majority of occupational physicians (n = 32 or 64%) believe that the presence of this unit would be beneficial in improving the management of occupational allergies within their occupational health department.

Conclusion

A majority of occupational physicians consider that practice can be improved, mainly in terms of primary and secondary prevention. The high level of support for the innovative project among occupational health physicians justifies its creation within the occupational health prevention department. In the future, the project will be evaluated to prove its usefulness and relevance.

研究目的研究罗讷河口省对暴露于职业过敏风险的员工的预防性管理以及职业医师的满意度。次要目的是研究职业医师对在职业健康预防部门内设立职业过敏科这一创新项目的兴趣。患者和方法描述性、横断面流行病学研究，包括在罗讷河口省职业健康预防部门工作并回答问卷的职业医师。一级预防（37 人，占 74%）和二级预防（33 人，占 66%）最受关注。三级预防的可改进程度较低（24 人，占 48%）。大多数职业医师（n = 32 或 64%）认为，在其职业健康部门内设立该单位将有利于改善职业过敏症的管理。职业健康医生对该创新项目的高度支持证明，在职业健康预防部门内设立该项目是合理的。今后，将对该项目进行评估，以证明其实用性和相关性。

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引用次数: 0