Revue Francaise d Allergologie最新文献

英文中文

Influence du sexe sur l’épidémiologie, la sévérité et la réponse au traitement de l’allergie alimentaire 性别对食物过敏的流行病学、严重程度和治疗反应的影响

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-16 DOI: 10.1016/j.reval.2024.104159

C. Elbany , P. Bégin

L’allergie alimentaire est un problème de santé publique croissant, affectant différemment hommes et femmes. La prédominance masculine durant l’enfance et féminine à l’âge adulte est observée dans diverses maladies atopiques. Les garçons montrent une prévalence plus élevée d’allergies alimentaires dans l’enfance, une tendance qui s’inverse chez les femmes jeunes avant de revenir à l’équilibre après la ménopause. Les hormones sexuelles jouent un rôle clé dans ces différences, modulant la dégranulation des mastocytes et favorisant ainsi les réactions allergiques. Au-delà de la prévalence, le sexe influence également la sévérité des allergies alimentaires. Les femmes adultes sont plus susceptibles de souffrir de réactions sévères, y compris d’anaphylaxie alimentaire induite par l’effort, tandis que les garçons présentent un risque accru de poly-allergie alimentaire durant l’enfance. Cependant, des paradoxes subsistent, comme la sévérité accrue de l’allergie à l’arachide chez les filles malgré une prévalence plus élevée chez les garçons. Cela souligne l’influence potentielle du genre et du comportement. La réponse aux traitements, notamment l’immunothérapie orale (ITO), varie également selon le sexe. Les filles présenteraient moins de réactions sévères avant 13 ans, tandis que les garçons en auraient moins après cet âge. En conclusion, une meilleure compréhension des influences sexospécifiques sur l’allergie alimentaire pourrait optimiser la prévention, le diagnostic et les traitements. Cette approche devrait tenir compte des différences hormonales, biologiques et socio-culturelles, ainsi que de l’influence du genre, pour une gestion plus efficace des allergies alimentaires.

食物过敏是一个日益严重的公共健康问题，对男性和女性的影响各不相同。在各种特应性疾病中，儿童期以男性为主，成年期以女性为主。男孩在童年时食物过敏的发病率较高，这一趋势在年轻女性中发生逆转，直到绝经后才恢复平衡。性激素在这些差异中起着关键作用，它能调节肥大细胞的脱颗粒作用，从而有利于过敏反应的发生。除了发病率，性别也会影响食物过敏的严重程度。成年女性更容易出现严重反应，包括运动诱发的食物过敏性休克，而男孩在儿童时期出现多种食物过敏的风险更大。然而，悖论依然存在，例如，尽管男孩花生过敏的发病率更高，但女孩花生过敏的严重程度却更高。这凸显了性别和行为的潜在影响。对治疗，尤其是口服免疫疗法（OIT）的反应也因性别而异。13 岁以前女孩的严重反应似乎较少，而 13 岁以后男孩的反应较少。总之，更好地了解不同性别对食物过敏的影响可以优化预防、诊断和治疗。这种方法应考虑荷尔蒙、生物和社会文化差异以及性别的影响，以便更有效地控制食物过敏。

{"title":"Influence du sexe sur l’épidémiologie, la sévérité et la réponse au traitement de l’allergie alimentaire","authors":"C. Elbany , P. Bégin","doi":"10.1016/j.reval.2024.104159","DOIUrl":"10.1016/j.reval.2024.104159","url":null,"abstract":"<div><div>L’allergie alimentaire est un problème de santé publique croissant, affectant différemment hommes et femmes. La prédominance masculine durant l’enfance et féminine à l’âge adulte est observée dans diverses maladies atopiques. Les garçons montrent une prévalence plus élevée d’allergies alimentaires dans l’enfance, une tendance qui s’inverse chez les femmes jeunes avant de revenir à l’équilibre après la ménopause. Les hormones sexuelles jouent un rôle clé dans ces différences, modulant la dégranulation des mastocytes et favorisant ainsi les réactions allergiques. Au-delà de la prévalence, le sexe influence également la sévérité des allergies alimentaires. Les femmes adultes sont plus susceptibles de souffrir de réactions sévères, y compris d’anaphylaxie alimentaire induite par l’effort, tandis que les garçons présentent un risque accru de poly-allergie alimentaire durant l’enfance. Cependant, des paradoxes subsistent, comme la sévérité accrue de l’allergie à l’arachide chez les filles malgré une prévalence plus élevée chez les garçons. Cela souligne l’influence potentielle du genre et du comportement. La réponse aux traitements, notamment l’immunothérapie orale (ITO), varie également selon le sexe. Les filles présenteraient moins de réactions sévères avant 13 ans, tandis que les garçons en auraient moins après cet âge. En conclusion, une meilleure compréhension des influences sexospécifiques sur l’allergie alimentaire pourrait optimiser la prévention, le diagnostic et les traitements. Cette approche devrait tenir compte des différences hormonales, biologiques et socio-culturelles, ainsi que de l’influence du genre, pour une gestion plus efficace des allergies alimentaires.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 1","pages":"Article 104159"},"PeriodicalIF":0.3,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Place des diététiciens dans le parcours d’immunothérapie orale alimentaire (ITO) 营养师在口服免疫疗法（OIT）计划中的作用

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-15 DOI: 10.1016/j.reval.2024.104168

A. Doc , Y. Shahali , A. Campion , R. Pontcharraud , S. d’Herlincourt , J.M. Rame

This article examines the crucial role of the Dietitian Nutritionist specialized in Allergology (DNA) in the oral immunotherapy (OIT) pathway for food allergies. We will describe the specific tasks of the DNA, who works by delegation and under the supervision of the allergist in the implementation and monitoring of OIT. The different perspectives of this role are discussed, based on available bibliographic data and on current practices as part of a recent care pathway experiment involving DNA and an allergist.

本文探讨了过敏症专业营养师（DNA）在食物过敏口服免疫疗法（OIT）中的关键作用。我们将介绍 DNA 的具体任务，DNA 在过敏学家的授权和监督下开展工作，实施并监控 OIT。我们将根据现有的文献资料和当前的实践，讨论这一角色的不同视角，这也是最近由 DNA 和过敏学家共同参与的护理路径实验的一部分。

引用次数: 0

Unveiling the paradox: Infliximab-induced pustular psoriasis in psoriasis vulgaris 揭开悖论的面纱：英夫利昔单抗诱发寻常型银屑病中的脓疱型银屑病

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-15 DOI: 10.1016/j.reval.2024.104165

K. Ferchichi , A. Chamli , R. Frioui , I. Helal , H. Hammami , A. Zaouak , S. Fenniche

Paradoxical psoriasis induced by tumor necrosis factor-alpha (TNF-α) antagonists is a rare adverse reaction of these drugs, with the pustular presentation being even more uncommon. Diagnosing and management of paradoxical pustular psoriasis in patients undergoing TNF-α antagonists treatment for psoriasis can be challenging. Therefore, we present a case report highlighting the occurrence of paradoxical pustular psoriasis caused by infliximab in a patient undergoing infliximab treatment for psoriasis, two weeks after the ninth injection. A switch to another TNF-α antagonist was considered, with no relapses at 6-month follow-up. This case underscores the importance of vigilant monitoring and recognition of atypical reactions and considering the switch to another TNF-α antagonist as a safe option for these patients.

肿瘤坏死因子-α（TNF-α）拮抗剂诱发的矛盾性银屑病是这类药物的一种罕见不良反应，而脓疱型银屑病则更为罕见。在接受 TNF-α 拮抗剂治疗的银屑病患者中，诊断和处理矛盾性脓疱型银屑病具有挑战性。因此，我们提交了一份病例报告，着重介绍了一名接受英夫利昔单抗治疗的银屑病患者在注射第九次英夫利昔单抗两周后出现的由英夫利昔单抗引起的矛盾性脓疱型银屑病。考虑改用另一种 TNF-α 拮抗剂后，随访 6 个月未再复发。该病例强调了对非典型反应进行警惕性监测和识别的重要性，并考虑将换用另一种TNF-α拮抗剂作为这些患者的安全选择。

引用次数: 0

Urticaire à l’uméclidinium bromure inhalé 吸入乌美溴铵引起的荨麻疹

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-15 DOI: 10.1016/j.reval.2024.104169

A.M. Rabain , J. Cottin , S. Bauler

We report a case of a man who developed urticaria 48 to 72 hours after inhaling umeclidinium bromide. Urticaria resolved after discontinuation umeclidinium treatment but recurred on reintroduction. Umeclidinium bromide is an anticholinergic inhaled treatment indicated in the background treatment of COPD, for which marketing authorization was obtained in 2014. The most frequent adverse reactions are: nasopharyngitis, headache, tachycardia, cough or pharyngeal pain, constipation, urinary tract infection or sinusitis. Effects related to antimuscarinic activity are of undetermined frequency. Allergic reactions to this product are rare.

我们报告了一例男子在吸入乌美司溴铵 48 至 72 小时后出现荨麻疹的病例。荨麻疹在停止使用乌美司啶治疗后缓解，但再次使用时又复发。乌美溴铵是一种抗胆碱能吸入治疗药物，适用于慢性阻塞性肺疾病的背景治疗，于2014年获得上市许可。最常见的不良反应有：鼻咽炎、头痛、心动过速、咳嗽或咽痛、便秘、尿路感染或鼻窦炎。与抗心绞痛药活性有关的不良反应发生频率尚不确定。对该产品的过敏反应非常罕见。

引用次数: 0

Allergie au céleri 对芹菜过敏

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-15 DOI: 10.1016/j.reval.2024.104142

M. Bouron , C. Dufrois , I. Himeur , J. Personnic , S. Saf , G. Benoist

Celery is an allergen not to be overlooked, as it is used in the food industry as well as in cosmetics. The prevalence of celery allergy remains low in the pediatric population, but is higher in adults, with a high risk of anaphylaxis. Celery allergens differ from one another in their characteristics: content within the different types of celery, sensitivity to heat, link with certain phenotypes (pollen-food syndrome). For diagnosis, native prick-tests are more sensitive than commercial extracts. Source-specific IgE may fail in a third of cases, and recombinant allergens are sometimes useful. Oral provocation testing is essential in cases of diagnostic doubt. The natural history of this allergy is not well described, and the cure rate is difficult to estimate. Avoidance of celery is the mainstay of treatment.

芹菜是一种不容忽视的过敏原，因为它被用于食品工业和化妆品中。芹菜过敏症在儿童中的发病率较低，但在成人中的发病率较高，过敏性休克的风险很高。芹菜过敏原的特征各不相同：不同种类芹菜中的含量、对热的敏感性、与某些表型（花粉-食物综合症）的联系。在诊断方面，原生刺入试验比商业提取物更敏感。在三分之一的病例中，源特异性 IgE 可能会失效，重组过敏原有时也很有用。在诊断有疑问的情况下，口服激发试验至关重要。对这种过敏症的自然病史描述不详，治愈率也难以估计。避免食用芹菜是治疗的主要方法。

引用次数: 0

Retours d’expérience d’une consultation pluridisciplinaire « Atopie sévère de l’enfant » aux Hospices Civils de Lyon 法国里昂平民临终关怀医院 "儿童严重过敏症 "多学科会诊的反馈意见

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-15 DOI: 10.1016/j.reval.2024.104145

L. Colin , M. Tauber , A.L. Souillet , L. Coutier , P. Reix , P. Biermé , A. Nosbaum , C. Braun

Context

Complexity of atopic trajectories, increased severity of atopic diseases and emergence of new therapies require expertise in atopy. Here, we would like to give feedbacks from a multidisciplinary consultation called “Severe atopy in children”, set up in the Hospices Civils de Lyon.

Methods

Retrospective reviews of patients’ charts were conducted.

Results

The consultation “Severe atopy in children” was conducted by pulmonologists, dermatologists, and immunologists with a training background of pediatricians and allergists. During this one-hour consultation, atopic conditions of various organs were evaluated and taken into consideration for specific, and if possible, global management, including the prescription of systemic treatments. In total, 48 children have accessed this consultation, all of whom are suffering from atopic dermatitis, with 68% having a severe form. Atopy comorbidity was found in 83% of patients, including 56% having IgE-mediated food allergy, 58% having asthma, and 60% having allergic rhinoconjunctivitis. A systemic treatment was prescribed to 62% of patients during the first consultation. Inhaled treatments were also optimized for asthmatics and the majority of food-allergic patients receiving oral immunotherapy in the follow-up.

Conclusion

The multidisciplinary consultation “Severe Atopy in Children” offers comprehensive care to children with atopic disorders and has the potential to become a cornerstone in the management of childhood atopy.

背景特应性疾病发展轨迹的复杂性、特应性疾病严重程度的增加以及新疗法的出现都需要特应性方面的专业知识。在此，我们想介绍一下里昂平民医院开展的名为 "儿童严重特应性 "的多学科会诊的反馈信息。结果 "儿童严重特应性 "会诊由具有儿科医生和过敏症医生培训背景的肺科医生、皮肤科医生和免疫科医生主持。在这一小时的会诊中，他们对不同器官的特应性病症进行了评估，并在可能的情况下，考虑到具体的全面治疗，包括开具系统治疗处方。共有 48 名儿童参加了这次会诊，他们都患有特应性皮炎，其中 68% 患有严重的特应性皮炎。83% 的患者合并有特应性皮炎，其中 56% 患有 IgE 介导的食物过敏，58% 患有哮喘，60% 患有过敏性鼻结膜炎。62% 的患者在首次就诊时接受了系统治疗。结论 "儿童严重特应性 "多学科会诊为患有特应性疾病的儿童提供了全面的治疗，有望成为儿童特应性治疗的基石。

{"title":"Retours d’expérience d’une consultation pluridisciplinaire « Atopie sévère de l’enfant » aux Hospices Civils de Lyon","authors":"L. Colin , M. Tauber , A.L. Souillet , L. Coutier , P. Reix , P. Biermé , A. Nosbaum , C. Braun","doi":"10.1016/j.reval.2024.104145","DOIUrl":"10.1016/j.reval.2024.104145","url":null,"abstract":"<div><h3>Context</h3><div>Complexity of atopic trajectories, increased severity of atopic diseases and emergence of new therapies require expertise in atopy. Here, we would like to give feedbacks from a multidisciplinary consultation called “Severe atopy in children”, set up in the Hospices Civils de Lyon.</div></div><div><h3>Methods</h3><div>Retrospective reviews of patients’ charts were conducted.</div></div><div><h3>Results</h3><div>The consultation “Severe atopy in children” was conducted by pulmonologists, dermatologists, and immunologists with a training background of pediatricians and allergists. During this one-hour consultation, atopic conditions of various organs were evaluated and taken into consideration for specific, and if possible, global management, including the prescription of systemic treatments. In total, 48 children have accessed this consultation, all of whom are suffering from atopic dermatitis, with 68% having a severe form. Atopy comorbidity was found in 83% of patients, including 56% having IgE-mediated food allergy, 58% having asthma, and 60% having allergic rhinoconjunctivitis. A systemic treatment was prescribed to 62% of patients during the first consultation. Inhaled treatments were also optimized for asthmatics and the majority of food-allergic patients receiving oral immunotherapy in the follow-up.</div></div><div><h3>Conclusion</h3><div>The multidisciplinary consultation “Severe Atopy in Children” offers comprehensive care to children with atopic disorders and has the potential to become a cornerstone in the management of childhood atopy.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"64 6","pages":"Article 104145"},"PeriodicalIF":0.3,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142437834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adieux à un maître et un ami, le Pr Bernard David (1935–2024) 向大师和朋友伯纳德-戴维教授（1935-2024 年）告别

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-10 DOI: 10.1016/j.reval.2024.104170

H. Chabane , P. Poncet , S. Mécheri

Né le 8 décembre 1935 à Noisy-le-Grand, Bernard David, professeur à l’Institut Pasteur, directeur de l’unité d’immuno-allergie de 1977 à 2000 est décédé le 15 juin 2024 à l’âge de 88 ans. Ses amis chercheurs, allergologues et biologistes adressent leurs sincères condoléances à sa famille et ses proches.

伯纳德-戴维于 1935 年 12 月 8 日出生于 Noisy-le-Grand，1977 年至 2000 年担任巴斯德研究所教授和免疫过敏部门主任，2024 年 6 月 15 日去世，享年 88 岁。他在研究、过敏学和生物学领域的朋友们向他的家人和朋友致以诚挚的哀悼。

引用次数: 0

Airborne fungal spores in Tétouan (NW of Morocco), sporal calendar and meteorogical parameters 特图安（摩洛哥西北部）空气中的真菌孢子、孢子日历和气象参数

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-09 DOI: 10.1016/j.reval.2024.104146

I. Hayoun, F. El Haskouri, H. Bouziane

The study aims to assess the diversity, dominance, interannual and seasonal variation of airborne fungal spores of Tétouan during 2015–2017, as well as the impact of meteorological parameters on their daily concentrations by using Spearman correlation and multivariate canonical correspondence analysis (CCA) to elucidate these relationships. Additionally, the study presents a fungal spore calendar, which serves to define the timing, duration, and intensity of spore emission. Aerobiological analysis revealed a high diversity of fungal spores, with over 63 types identified. The annual spore integral (ASIn) varied between 502,910 in 2016 and 666,705 spore * d/m³ in 2015. Predominantly, spore types belonged to the groups of Ascomycota (82%, including fungi imperfecti), Basidiomycota (15%), and Zygomycota (3%). The most abundant species included Cladosporium, Ustilago, Alternaria, Leptospharia, Oidium agent spores, Aspergillaceae, Stemphylium, Torula, Arthrinium, and Pleospora, generally between spring and fall. Temperature emerged as a crucial factor in the dispersal of Alternaria, Cladosporium, Stemphylium, Torula, and Ustilago spores, whereas Ascospores, Leptosphaeria, Pleospora, and basidiospores exhibited positive and significant correlations with humidity and precipitation. The fungal spore calendar illustrated the diversity of spores (16 types), their presence throughout the year, and extended spore emission periods. However, the presence of fungal spores varied annually based on local weather factors and could potentially cause health risks to allergic individuals. Overall, the study sheds light on the complex interactions between fungal spores and meteorological parameters, providing valuable insights into airborne fungal ecology and its implications for human health.

该研究旨在评估2015-2017年期间特图安空气中真菌孢子的多样性、优势、年际和季节变化，以及气象参数对其日浓度的影响，采用斯皮尔曼相关性和多元典型对应分析（CCA）来阐明这些关系。此外，该研究还提出了真菌孢子日历，用于确定孢子排放的时间、持续时间和强度。空气生物学分析表明，真菌孢子种类繁多，已确定的种类超过 63 种。年度孢子积分（ASIn）在 2016 年的 502 910 和 2015 年的 666 705 孢子 * d/m3 之间变化。孢子类型主要属于子囊菌（Ascomycota）（82%，包括不完全真菌）、担子菌（Basidiomycota）（15%）和子囊菌（Zygomycota）（3%）。最多的种类包括 Cladosporium、Ustilago、Alternaria、Leptospharia、Oidium agent spores、Aspergillaceae、Stemphylium、Torula、Arthrinium 和 Pleospora，一般出现在春季和秋季之间。温度是影响交替孢属（Alternaria）、帚孢属（Cladosporium）、担子菌属（Stemphylium）、疣孢属（Torula）和乌丝菌属（Ustilago）孢子传播的关键因素，而升孢属（Ascospores）、钩孢属（Leptosphaeria）、褶孢属（Pleospora）和基生孢属（basidiospores）则与湿度和降水量呈显著正相关。真菌孢子日历显示了孢子的多样性（16 种）、全年存在以及孢子排放期的延长。不过，真菌孢子的存在每年因当地天气因素而异，可能会对过敏体质的人造成健康风险。总之，这项研究揭示了真菌孢子与气象参数之间复杂的相互作用，为了解空气中的真菌生态及其对人类健康的影响提供了宝贵的见解。

{"title":"Airborne fungal spores in Tétouan (NW of Morocco), sporal calendar and meteorogical parameters","authors":"I. Hayoun, F. El Haskouri, H. Bouziane","doi":"10.1016/j.reval.2024.104146","DOIUrl":"10.1016/j.reval.2024.104146","url":null,"abstract":"<div><div>The study aims to assess the diversity, dominance, interannual and seasonal variation of airborne fungal spores of Tétouan during 2015–2017, as well as the impact of meteorological parameters on their daily concentrations by using Spearman correlation and multivariate canonical correspondence analysis (CCA) to elucidate these relationships. Additionally, the study presents a fungal spore calendar, which serves to define the timing, duration, and intensity of spore emission. Aerobiological analysis revealed a high diversity of fungal spores, with over 63 types identified. The annual spore integral (ASIn) varied between 502,910 in 2016 and 666,705 spore * d/m<sup>3</sup> in 2015. Predominantly, spore types belonged to the groups of Ascomycota (82%, including fungi imperfecti), Basidiomycota (15%), and Zygomycota (3%). The most abundant species included <em>Cladosporium</em>, <em>Ustilago</em>, <em>Alternaria</em>, <em>Leptospharia</em>, Oidium agent spores, Aspergillaceae, <em>Stemphylium</em>, <em>Torula</em>, <em>Arthrinium</em>, and <em>Pleospora</em>, generally between spring and fall. Temperature emerged as a crucial factor in the dispersal of <em>Alternaria</em>, <em>Cladosporium</em>, <em>Stemphylium</em>, <em>Torula</em>, and <em>Ustilago</em> spores, whereas Ascospores, <em>Leptosphaeria</em>, <em>Pleospora</em>, and basidiospores exhibited positive and significant correlations with humidity and precipitation. The fungal spore calendar illustrated the diversity of spores (16 types), their presence throughout the year, and extended spore emission periods. However, the presence of fungal spores varied annually based on local weather factors and could potentially cause health risks to allergic individuals. Overall, the study sheds light on the complex interactions between fungal spores and meteorological parameters, providing valuable insights into airborne fungal ecology and its implications for human health.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"64 6","pages":"Article 104146"},"PeriodicalIF":0.3,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142428709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allergies aux fientes d’oiseaux 对鸟粪过敏

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-09 DOI: 10.1016/j.reval.2024.104144

R. Abdellaziz , E. Sadi , M. Ouali , N. Mazouz

The problems of human–bird cohabitation are not a recent phenomenon even if today their importance has taken on an indisputable extent. Their droppings contain significant concentrations of microorganisms and can cause allergic diseases, such as hypersensitivity pneumonitis (HSP), formerly called extrinsic allergic alveolitis, but also rhinitis, asthma or conjunctivitis. We report a rare case of allergy to bird droppings in a patient who raises chickens and canaries, having consulted for rhinoconjunctivitis whose allergological assessment found sensitization of these droppings with positive skin and specific IgE tests. Its management consisted of avoiding the risk with medical treatment. It is a rare pathology that must be considered in the event of exposure to birds.

人鸟共处的问题并不是最近才出现的现象，尽管如今其重要性已无可争议。鸟粪中含有大量微生物，可引起过敏性疾病，如过敏性肺炎（HSP），以前称为外源性过敏性肺泡炎，也可引起鼻炎、哮喘或结膜炎。我们报告了一例罕见的对鸟粪过敏的病例，患者饲养鸡和金丝雀，曾因鼻结膜炎就诊，过敏评估发现其对鸟粪过敏，皮肤和特异性 IgE 检测呈阳性。治疗方法是通过药物治疗来避免风险。这是一种罕见的病理现象，在接触鸟类时必须予以考虑。

引用次数: 0

Dupilumab induced maculopapular exanthema: A case report 杜匹单抗诱发的斑丘疹性红斑：病例报告

IF 0.3 4区医学

Revue Francaise d Allergologie

Pub Date : 2024-10-09 DOI: 10.1016/j.reval.2024.104143

L. Benjelloun , P. Bonniaud , A. Grandvuillemin , E. Collet , C. Leleu

Dupilumab is a fully human anti-interleukin-4-and 13 monoclonal antibody commonly used in the treatment of severe atopic dermatitis and severe asthma. We report a case of maculopapular exanthema that occurred after the first injection of dupilumab in a young patient treated for severe asthma.

杜匹鲁单抗是一种全人源抗白细胞介素-4-13单克隆抗体，常用于治疗严重特应性皮炎和严重哮喘。我们报告了一例因严重哮喘而接受治疗的年轻患者在首次注射杜匹单抗后出现斑丘疹性红斑的病例。

引用次数: 0

首页上一页

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Revue Francaise d Allergologie

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀