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Design and Performance Testing of a Novel In Vivo Laparoscope Lens Cleaning Device 一种新型体内腹腔镜镜头清洁装置的设计与性能测试
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-09-01 DOI: 10.1115/1.4050955
Christopher R. Idelson, John M. Uecker, James Garcia, Sunjna Kohli, G. Handing, Vishrudh Sriramprasad, Kirstie Yong, Christopher G. Rylander
A common tool for diagnosis and treatment of gastrointestinal, gynecologic, and other anatomical pathologies is a form of minimally invasive surgery known as laparoscopy. Roughly 4 × 106 laparoscopic surgeries are performed in the U.S. every year, with an estimated 15 × 106 globally. During surgeries, lens clarity often becomes impaired via (1) condensation or (2) smearing of bodily fluids and tissues. The current gold standard solution requires scope removal from the body for cleaning, offering opportunity for decreased surgical safety and efficiency, while simultaneously generating mounting frustration for the operating room team. A novel lens cleaning device was designed and developed to clean a laparoscope lens in vivo during surgery. Benchtop experiments in a warm body simulated environment allowed quantification of lens cleaning efficacy for several lens contaminants. Image analysis techniques detected the differences between original (clean), postdebris, and postcleaning images. Mechanical testing was also executed to determine safety levels regarding potential misuse scenarios. Compared to gold standard device technologies, the novel lens cleaning device prototype showed strong performance and ability to clear a laparoscope lens of debris while mitigating the need for scope removal from the simulated surgical cavity. Mechanical testing results also suggest the design also holds inherently strong safety performance. Both objective metrics and subjective observation suggests the novel design holds promise to improve safety and efficiency during laparoscopic surgery.
诊断和治疗胃肠道、妇科和其他解剖病理的常用工具是一种被称为腹腔镜的微创手术。美国每年大约进行4 × 106例腹腔镜手术,全球估计为15 × 106例。在手术过程中,晶状体的清晰度通常会因(1)体液和组织的凝结或(2)涂抹而受损。目前的金标准解决方案需要将手术镜从体内取出进行清洁,这可能会降低手术的安全性和效率,同时也会给手术室团队带来越来越多的挫败感。设计并研制了一种新型的晶状体清洁装置,用于手术过程中对腹腔镜晶状体的体内清洁。在一个温暖的身体模拟环境的台式实验允许对几种透镜污染物的透镜清洁效果进行量化。图像分析技术检测原始(清洁)、碎片后和清洁后图像之间的差异。还进行了机械测试,以确定潜在误用情况下的安全水平。与金标准装置技术相比,新型晶状体清洁装置原型显示出强大的性能和清除腹腔镜晶状体碎片的能力,同时减少了从模拟手术腔中取出镜的需要。机械测试结果也表明,这种设计本身也具有很强的安全性能。客观指标和主观观察表明,这种新颖的设计有望提高腹腔镜手术的安全性和效率。
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引用次数: 0
Feasibility of a One Degree-of-Freedom Linear Robot for Bed-Bound Stroke Rehabilitation 一自由度线性中风卧床康复机器人的可行性研究
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-09-01 DOI: 10.1115/1.4050454
N. Berezny, D. Dowlatshahi, M. Ahmadi
A 1DOF lower limb rehabilitation robot is presented for delivering leg extension therapy to bed-bound stroke patients. Such a compact and minimal system may be beneficial in terms of compatibility with pre-existing hospital equipment, ease-of-use, safety, and cost. A set of design criteria was created based on the literature and on previous field work at a local hospital. The device uses admittance control to apply assistive or resistive forces, and can also use haptic feedback to increase user engagement. A pilot study on six healthy participants was used to determine the feasibility of such a minimal system in administering assistance or resistance through the leg extension exercise. Results indicate that a single DOF is capable of decreasing trajectory error with assistance and increasing user effort with resistance. Observations confirm that the minimal system is effective; however, extending the robot with additional DOFs so that it can target multiple bed-bound exercises may help to increase therapy duration.
提出了一种为卧床中风患者提供腿部伸展治疗的1DOF下肢康复机器人。这样一个紧凑和最小的系统在与现有医院设备的兼容性、易用性、安全性和成本方面可能是有益的。根据文献和以前在当地医院的实地工作,创建了一套设计标准。该设备使用导纳控制来施加辅助或阻力,也可以使用触觉反馈来增加用户参与度。对六名健康参与者进行了试点研究,以确定这种最小系统通过腿部伸展运动给予辅助或阻力的可行性。结果表明,单自由度在辅助的情况下可以减小轨迹误差,在阻力的情况下可以增加操作难度。观测证实最小系统是有效的;然而,给机器人增加额外的自由度,这样它就可以针对多次卧床锻炼,这可能有助于延长治疗时间。
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引用次数: 1
Examination of Mechanical Properties and Photoelastic Properties of Gel Material for Blood Vesssel Mimics 血管模拟用凝胶材料的力学性能和光弹性性能研究
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-09-01 DOI: 10.1115/1.4051516
Daichi Yamada, Simon Hori, Shuhei Abe, Yuki Kumeno, T. Yamazaki, C. Oka, J. Sakurai, S. Hata
Catheter surgery is a minimally invasive treatment in which visual information is limited to a two-dimensional image generated by an X-ray camera. This results in the possibility that stress applied by the catheter onto a blood vessel wall damages the vessel. Doctors must therefore be skillful at catheter surgery. We proposed a catheter surgery simulator that visualizes the stress applied to the blood vessel wall using photoelasticity. The manufacture of this simulator requires creating blood vessel mimics that reproduce the physical properties of blood vessel tissue using photoelasticity. This study investigated the mechanical and photoelastic properties of gel materials and selected a gel composition suitable for making blood vessel mimics. The mechanical properties of polyvinyl alcohol (PVA) hydrogel changed in the range 70–335 kPa by changing the composition ratio, and double network (DN) gel changed in the range 0.13–1.06 MPa by changing the composition ratio. These gels could be adjusted by changing the material composition to provide Young's moduli similar to that of blood vessels. The photoelastic properties of PVA hydrogel changed in the range 1.38–2.76 × 10−9/Pa by changing the composition ratio, and DN gel changed in the range 0.012–0.029 × 10−9/Pa by changing the composition ratio.
导管手术是一种微创治疗,其中视觉信息仅限于x射线相机生成的二维图像。这导致导管施加在血管壁上的压力可能会损坏血管。因此,医生必须精通导管手术。我们提出了一种导管手术模拟器,可以利用光弹性来可视化施加在血管壁上的应力。制造这个模拟器需要创造血管模拟物,利用光弹性再现血管组织的物理特性。本研究考察了凝胶材料的力学和光弹性性能,并选择了一种适合制作血管模拟物的凝胶组合物。通过改变组成比,聚乙烯醇(PVA)水凝胶的力学性能在70 ~ 335 kPa范围内发生变化;通过改变组成比,双网(DN)凝胶的力学性能在0.13 ~ 1.06 MPa范围内变化。这些凝胶可以通过改变材料成分来调节,以提供类似于血管的杨氏模量。通过改变组成比,PVA水凝胶的光弹性变化范围为1.38 ~ 2.76 × 10−9/Pa;通过改变组成比,DN凝胶的光弹性变化范围为0.012 ~ 0.029 × 10−9/Pa。
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引用次数: 1
A Vibratory, Subresonant Diagnostic Device to Measure Dental Implant Stability Via Angular Stiffness 一种通过角刚度测量牙种植体稳定性的振动亚共振诊断装置
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-09-01 DOI: 10.1115/1.4051832
Weiwei Xu, Darwin S. Wood, Yifeng Liu, I. Shen
Stability of a dental implant reflects quality of osseointegration between the implant and its surrounding bone. While many methods have been proposed to characterize implant stability, angular stiffness at the neck of the implant has been proven to be a rigorous and accurate measure. Nevertheless, fast and reliable measurements of the angular stiffness in a clinical environment are not yet available. This article is to demonstrate a novel stability diagnostic device that can measure the angular stiffness accurately in clinical environments. The device consists of a sensing unit, a controller unit, and a mobile app. In the sensing unit, a coupler attaches a buzzer motor and a tiny accelerometer to an abutment of an implant, whose angular stiffness is to be measured. The buzzer vibrates at a frequency below the resonance frequency of the implant–bone–abutment system. Meanwhile, the accelerometer measures the abutment's vibration. The controller unit powers the buzzer, reads the accelerometer data, and transmits the data to the mobile app. The mobile app postprocesses the data and extracts the angular stiffness through use of a finite element model and a nonlinear regression algorithm. The extracted angular stiffness is compared with a calibrated angular stiffness, which is obtained independently via a force hammer and a laser Doppler vibrometer. The comparison shows reasonable agreement, with the difference being in the range of 4–20%.
牙科植入物的稳定性反映了植入物与其周围骨骼之间的骨整合质量。虽然已经提出了许多方法来表征植入物的稳定性,但植入物颈部的角刚度已被证明是一种严格而准确的测量方法。然而,在临床环境中还不能快速可靠地测量角刚度。本文旨在展示一种新型的稳定性诊断设备,该设备可以在临床环境中准确测量角刚度。该设备由传感单元、控制器单元和移动应用程序组成。在传感单元中,一个耦合器将一个蜂鸣器电机和一个微型加速度计连接到植入物的基台上,植入物的角刚度将被测量。蜂鸣器的振动频率低于植入物-骨-基台系统的共振频率。同时,加速度计测量桥台的振动。控制器单元为蜂鸣器供电,读取加速度计数据,并将数据传输到移动应用程序。该移动应用程序通过使用有限元模型和非线性回归算法对数据进行后处理并提取角刚度。将提取的角刚度与通过力锤和激光多普勒振动计独立获得的校准角刚度进行比较。比较显示出合理的一致性,差异在4–20%的范围内。
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引用次数: 0
A Computational Method for the Estimation of the Geometrical and Thermophysical Properties of Tumor Using Contact Thermometry 用接触测温法估算肿瘤几何和热物理性质的一种计算方法
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-09-01 DOI: 10.1115/1.4051517
N. Sudarsan, K. Arathy, Linta Antony, R. S. Sudheesh, M. N. Muralidharan, B. Satheesan, Seema Ansari
Contact thermometry is the measurement of surface temperature using sensors in contact with the medium. These surface temperatures can be potential indicators of any abnormality possibly a tumor. This research work aims to present a computation method that makes use of contact thermometry to estimate the geometric center, size, and thermophysical properties of breast tumor. Wearable thermal sensors captured real-time surface temperature readings from discrete point locations. The continuous heat distribution over the domain was formulated using forward heat transfer analysis. The optimization method estimated tumor parameters of the breast, and a three-dimensional thermal model was developed from the estimated parameters. Laboratory experiments on breast phantoms were done to validate the estimation method. Furthermore, real-time temperature readings of human subjects were recorded, and the estimated location and size were then compared with the mammogram results. It was found that the estimated two-dimensional geometric center and the size in diameter of the tumor closely match with the mammogram results. Further, the thermophysical properties estimated using the proposed method had a higher order in subjects having a tumor making it a tool for breast cancer screening.
接触式测温是使用与介质接触的传感器测量表面温度。这些表面温度可能是任何异常的潜在指标,可能是肿瘤。本研究工作旨在提出一种利用接触测温来估计乳腺肿瘤的几何中心、大小和热物理性质的计算方法。可佩戴的热传感器从离散的点位置捕获实时表面温度读数。采用正向传热分析法,对整个区域的连续热分布进行了公式化。该优化方法估计了乳腺的肿瘤参数,并根据估计的参数建立了三维热模型。在乳腺模型上进行了实验室实验,验证了该估计方法。此外,记录人类受试者的实时体温读数,然后将估计的位置和大小与乳房X光检查结果进行比较。发现估计的二维几何中心和肿瘤的直径大小与乳房X光检查结果非常吻合。此外,使用所提出的方法估计的热物理性质在患有肿瘤的受试者中具有更高的阶数,使其成为乳腺癌症筛查的工具。
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引用次数: 2
VEMERS UC: A Clinically Validated Emergency Mechanical Ventilator for COVID-19 and Postpandemic Use in Low Resource Communities VEMERS UC:用于COVID-19和低资源社区大流行后临床验证的紧急机械呼吸机
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-09-01 DOI: 10.1115/1.4051246
L. Chiang, Felipe A. Castro
In this article, we present a clinically validated invasive emergency mechanical ventilator developed in Chile called VEMERS UC. It has been clinically tested and validated in intubated Covid-19 patients. Once the pandemic hit Chilean soil in March 2020, it was quite clear that the number of mechanical ventilators available would not be enough. As in other parts of the world many initiatives sprung, most of them naively simple. Chilean medical societies joined engineering specialists and agreed early on in an organized and regulated open process for validating emergency mechanical ventilators, thus allowing for rapid development but with the required functionality, reliability, and safety features. VEMERS UC was one of a few that completed successfully all stages of the validating process, the final test being on five critically ill intubated Covid-19 patients for eight hours each. VEMERS UC is based on an electropneumatic circuit architecture, and its components are all low cost, off-the-shelf pneumatic, and electronic products easily obtained in industrial markets. It works in continuous mandatory volume control mode. The novel technical features of VEMERS UC are discussed here as well as the results obtained in each stage of the validating process. The validating process carried out in Chile is noteworthy by itself, and it could be used as an example in other developing countries. Furthermore, VEMERS UC can be used as a guiding design reference in other countries as well, since this design has already been thoroughly tested in human patients and has proven to work successfully.
在这篇文章中,我们介绍了一种在智利开发的临床验证的有创紧急机械呼吸机,称为VEMERS UC。已在新冠肺炎插管患者中进行了临床试验和验证。当疫情在2020年3月袭击智利时,很明显,可用的机械呼吸机数量不够。就像在世界其他地方一样,出现了许多倡议,其中大多数都非常简单。智利的医学协会加入了工程专家,并在早期就有组织和规范的开放过程中达成一致,以验证紧急机械呼吸机,从而允许快速开发,但具有所需的功能、可靠性和安全性。VEMERS UC是少数几个成功完成验证过程所有阶段的公司之一,最后的测试是对5名危重患者进行插管,每人8小时。VEMERS UC基于电气动电路架构,其组件都是低成本的,现成的气动和电子产品,很容易在工业市场上获得。它在连续强制音量控制模式下工作。本文讨论了VEMERS UC的新技术特点以及在验证过程的每个阶段获得的结果。在智利进行的验证过程本身是值得注意的,它可以作为其他发展中国家的一个例子。此外,VEMERS UC也可以作为其他国家的指导性设计参考,因为这种设计已经在人类患者身上进行了彻底的测试,并被证明是成功的。
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引用次数: 2
Neuromodulation Applications for Chronic Pain 慢性疼痛的神经调节应用
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-08-12 DOI: 10.1115/1.4052123
Dharam Persaud-Sharma, J. Mallett, G. Panjeton, Blessing Ogbemudia, Affan Ahmad, S. Coombes, Ajay Antony
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引用次数: 1
Pre-Lubricated Polypropylene Injector for Breast Implant Delivery 乳房植入物输送用预润滑聚丙烯注射器
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-08-12 DOI: 10.1115/1.4052122
Hsiao-Hung Chaing, Chen-Ying Su, Hsiu-Peng Lin, Chiao-Pei Chen, Ting-Chu Yu, Hsu-Wei Fang
Breast augmentation is a common aesthetic surgery, and there are two major surgical methods for breast implant delivery: the finger method and the plastic film method. There are advantages and disadvantages for each method, and we have developed a pre-lubricated polypropylene (PP) injector that might be the most suitable device for delivering breast implants. By covering the interior surface of the injector with the hydrophilic coating, the friction coefficient was significantly reduced when sliding a silicone sled against the pre-lubricated PP injector. In order to confirm the pre-lubricated PP injector would not damage the breast implant, fatigue testing was performed and the result showed the injector did not cause rupture or microleakage of the breast implant. In addition, the cell viability result demonstrated the pre-lubricated PP injector was biocompatible. In addition, the pre-lubricated PP injector provides a small incision site and stability during breast implant delivery. Our results provided evidence that the pre-lubricated PP injector is a smooth and safe method for breast implant delivery.
隆胸是一种常见的美容手术,隆胸植入物的输送主要有两种手术方式:指法和塑料膜法。每种方法各有优缺点,我们开发了一种预润滑聚丙烯(PP)注射器,它可能是最适合植入乳房的装置。通过将亲水性涂层覆盖进样器的内表面,在预润滑的PP进样器上滑动硅胶滑橇时,摩擦系数显著降低。为了确认预润滑PP注入器不会损坏乳房假体,我们进行了疲劳测试,结果显示注入器不会造成乳房假体破裂或微泄漏。此外,细胞活力结果表明预润滑PP注射器具有生物相容性。此外,预润滑PP注射器提供了一个小的切口位置和稳定的乳房植入物交付。我们的研究结果证明预润滑PP注射器是一种平稳、安全的乳房植入方法。
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引用次数: 0
A Systematic Review of Compliant Mechanisms as Orthopedic Implants 骨科植入物柔顺机制的系统综述
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-08-06 DOI: 10.1115/1.4052011
Connor Huxman, Jared Butler
{"title":"A Systematic Review of Compliant Mechanisms as Orthopedic Implants","authors":"Connor Huxman, Jared Butler","doi":"10.1115/1.4052011","DOIUrl":"https://doi.org/10.1115/1.4052011","url":null,"abstract":"","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":"58 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86877777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Characterization and Validation of Fatigue Strains for Superelastic Nitinol using Digital Image Correlation 超弹性镍钛诺疲劳应变的数字图像相关表征与验证
IF 0.9 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2021-08-06 DOI: 10.1115/1.4052012
Koray Senol, H. Cao, S. Tripathy
{"title":"Characterization and Validation of Fatigue Strains for Superelastic Nitinol using Digital Image Correlation","authors":"Koray Senol, H. Cao, S. Tripathy","doi":"10.1115/1.4052012","DOIUrl":"https://doi.org/10.1115/1.4052012","url":null,"abstract":"","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":"10 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87868241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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Journal of Medical Devices-Transactions of the Asme
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