Pub Date : 2025-02-01Epub Date: 2025-11-27DOI: 10.1115/1.4070016
Keith Kleinman, James L Dean, Erika Yu, Blake A Schreurs, Justin M Jeffers
Pediatric cardiopulmonary resuscitation (CPR) quality remains inconsistent, with low adherence to guideline-recommended compression rate and depth. Augmented reality cardiopulmonary resuscitation (AR-CPR) is an augmented reality feedback system designed to improve CPR performance using real-time, in-view coaching via smart glasses. To validate the accuracy and precision of the AR-CPR system in measuring chest compression rate and depth across clinically relevant ranges, we tested AR-CPR using a programable oscillation platform at five rates (100-140 compressions per minute (CPM)) and four depths (4.0-5.5 cm), and with the Stryker LUCAS3 device at 102 CPM and 5.3 cm. A total of 473 compressions (slide test) and 559 compressions (LUCAS3 test) were analyzed. Statistical methods included intraclass correlation coefficients (ICC[2,1]), paired t-tests, Bland-Altman analysis, root-mean-square error (RMSE), kernel density estimation for error distribution, and group error modeling to estimate clinical thresholds (±2.5 CPM, ±0.5 cm). Linearity was assessed via linear regression. The AR-CPR system demonstrated high accuracy and reliability in 473 simulated and 559 mechanical compressions. Mean biases were minimal for rate (-0.48, -0.44 CPM) and depth (+0.39, +0.59 cm), with excellent ICCs (0.997 rate, 0.944 depth). Errors were normally distributed, with <7% exceeding clinically relevant thresholds. R2 values (0.994 rate, 0.903 depth) confirmed strong linear agreement with reference values. AR-CPR reliably measured compression rate and depth with high accuracy and precision across variable and fixed testing conditions. Its portability, real-time feedback, and robust signal processing support its potential for improving pediatric resuscitation training and clinical performance.
{"title":"AR-CPR 2.0: Validation of the Accuracy and Precision of a Wearable Coaching System for Improving Chest Compression Performance.","authors":"Keith Kleinman, James L Dean, Erika Yu, Blake A Schreurs, Justin M Jeffers","doi":"10.1115/1.4070016","DOIUrl":"10.1115/1.4070016","url":null,"abstract":"<p><p>Pediatric cardiopulmonary resuscitation (CPR) quality remains inconsistent, with low adherence to guideline-recommended compression rate and depth. Augmented reality cardiopulmonary resuscitation (AR-CPR) is an augmented reality feedback system designed to improve CPR performance using real-time, in-view coaching via smart glasses. To validate the accuracy and precision of the AR-CPR system in measuring chest compression rate and depth across clinically relevant ranges, we tested AR-CPR using a programable oscillation platform at five rates (100-140 compressions per minute (CPM)) and four depths (4.0-5.5 cm), and with the Stryker LUCAS3 device at 102 CPM and 5.3 cm. A total of 473 compressions (slide test) and 559 compressions (LUCAS3 test) were analyzed. Statistical methods included intraclass correlation coefficients (ICC[2,1]), paired t-tests, Bland-Altman analysis, root-mean-square error (RMSE), kernel density estimation for error distribution, and group error modeling to estimate clinical thresholds (±2.5 CPM, ±0.5 cm). Linearity was assessed via linear regression. The AR-CPR system demonstrated high accuracy and reliability in 473 simulated and 559 mechanical compressions. Mean biases were minimal for rate (-0.48, -0.44 CPM) and depth (+0.39, +0.59 cm), with excellent ICCs (0.997 rate, 0.944 depth). Errors were normally distributed, with <7% exceeding clinically relevant thresholds. R<sup>2</sup> values (0.994 rate, 0.903 depth) confirmed strong linear agreement with reference values. AR-CPR reliably measured compression rate and depth with high accuracy and precision across variable and fixed testing conditions. Its portability, real-time feedback, and robust signal processing support its potential for improving pediatric resuscitation training and clinical performance.</p>","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":"20 1","pages":"011007"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12755165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01Epub Date: 2024-09-30DOI: 10.1115/1.4066445
Samantha Stewart, Alisa White, Wenquan Ou, Wei Liu, Jennifer Nagashima, Nucharin Songsasen, Xiaoming He
Ovarian follicle cryopreservation is a promising strategy for fertility preservation; however, cryopreservation protocols have room for improvement to maximize post-thaw follicle viability and quality. Current slow-freezing protocols use either manual ice-seeding in combination with expensive programmable-rate freezers or other clinically incompatible ice initiators to control the ice-seeding temperature in the extracellular solution, a critical parameter that impacts post-cryopreservation cell/tissue quality. Previously, sand has been shown to be an excellent, biocompatible ice initiator, and its use in cryopreservation of human induced pluripotent stem cells enables high cell viability and quality after cryopreservation. This study applies sand as an ice initiator to cryopreserve multicellular microtissue, preantral ovarian follicles, using a simple slow-freezing protocol in the mouse model. Ovarian follicles cryopreserved using the sand partially embedded in polydimethylsiloxane (PDMS) film to seed ice in the extracellular solution exhibit healthy morphology, high viability, and the ability to grow similarly to fresh follicles in culture post-thaw. This sand-based cryopreservation strategy can facilitate convenient ovarian follicle cryopreservation using simple equipment, and this study further demonstrates the translatability of this strategy to not only single cells but also multicellular tissues.
{"title":"Controlled Ice Nucleation With a Sand-PDMS Film Device Enhances Cryopreservation of Mouse Preantral Ovarian Follicles.","authors":"Samantha Stewart, Alisa White, Wenquan Ou, Wei Liu, Jennifer Nagashima, Nucharin Songsasen, Xiaoming He","doi":"10.1115/1.4066445","DOIUrl":"10.1115/1.4066445","url":null,"abstract":"<p><p>Ovarian follicle cryopreservation is a promising strategy for fertility preservation; however, cryopreservation protocols have room for improvement to maximize post-thaw follicle viability and quality. Current slow-freezing protocols use either manual ice-seeding in combination with expensive programmable-rate freezers or other clinically incompatible ice initiators to control the ice-seeding temperature in the extracellular solution, a critical parameter that impacts post-cryopreservation cell/tissue quality. Previously, sand has been shown to be an excellent, biocompatible ice initiator, and its use in cryopreservation of human induced pluripotent stem cells enables high cell viability and quality after cryopreservation. This study applies sand as an ice initiator to cryopreserve multicellular microtissue, preantral ovarian follicles, using a simple slow-freezing protocol in the mouse model. Ovarian follicles cryopreserved using the sand partially embedded in polydimethylsiloxane (PDMS) film to seed ice in the extracellular solution exhibit healthy morphology, high viability, and the ability to grow similarly to fresh follicles in culture post-thaw. This sand-based cryopreservation strategy can facilitate convenient ovarian follicle cryopreservation using simple equipment, and this study further demonstrates the translatability of this strategy to not only single cells but also multicellular tissues.</p>","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":"18 4","pages":"041007"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11500804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract This paper innovatively proposes an artificial knee joint customization design scheme based on modular wearable sensors. It aims to solve the compatibility and security problem of wearable devices for different individual knee joints. The method consists of two main parts: measurement and customization. A wearable sensor with three joints is proposed and analyzed. The sensor can measure the kinematic characteristics of human knee joints to obtain the customized design parameters of artificial joints. Designed a bionic four-link knee joint, and the parameters of the connecting rod were optimized by a genetic algorithm based on the measured data. In particular, the measuring device and knee joint are designed in a modular way, and they can be used on the same platform. The modular design method can be used to customize joints for different individuals, which simplifies the difficulty of customization and effectively reduces the cost. After the modular knee joint's optimized design, this paper mainly conducted a number of comparative tests. The comparative test results of three joints show that the dynamic tracking accuracy of customized joints is 54.9% higher than that of ordinary joints and 70.5% higher than that of hinge joints. The results show that personalized customization for individuals can improve human-machine coupling performance.
{"title":"A Novel Design Method for the Knee Joint of the Exoskeleton Based On the Modular Wearable Sensor","authors":"Jian Cao, Chang Wang, Jianhua Zhang, Kexiang Li, Jianjun Zhang","doi":"10.1115/1.4063672","DOIUrl":"https://doi.org/10.1115/1.4063672","url":null,"abstract":"Abstract This paper innovatively proposes an artificial knee joint customization design scheme based on modular wearable sensors. It aims to solve the compatibility and security problem of wearable devices for different individual knee joints. The method consists of two main parts: measurement and customization. A wearable sensor with three joints is proposed and analyzed. The sensor can measure the kinematic characteristics of human knee joints to obtain the customized design parameters of artificial joints. Designed a bionic four-link knee joint, and the parameters of the connecting rod were optimized by a genetic algorithm based on the measured data. In particular, the measuring device and knee joint are designed in a modular way, and they can be used on the same platform. The modular design method can be used to customize joints for different individuals, which simplifies the difficulty of customization and effectively reduces the cost. After the modular knee joint's optimized design, this paper mainly conducted a number of comparative tests. The comparative test results of three joints show that the dynamic tracking accuracy of customized joints is 54.9% higher than that of ordinary joints and 70.5% higher than that of hinge joints. The results show that personalized customization for individuals can improve human-machine coupling performance.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135254599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinxiao Li, Jiaqi Yang, Patrick Chernjavsky, Katerina Angjeli, Yang Liu, Yihao Zheng
Abstract Rotational atherectomy (RA) is a minimally invasive procedure to remove the calcified atherosclerotic plaque from arteries to restore blood flow. It uses a high-speed, metal-bonded diamond abrasive grinding wheel to pulverize the calcified plaque into absorbable debris via a catheter through the artery. Although RA has been clinically used for over two decades, procedural complications persist and there remains a lack of consensus on the optimal device parameters. This study aims to investigate RA material removal rate (MRR) with respect to grinding wheel sizes and rotational speeds based on a tissue-mimicking phantom. Three grinding wheel sizes, 1.25, 1.5, and 1.75 mm in diameter, and three rotational speeds, 120,000, 150,000, and 180,000 rpm, were investigated. The RA MRR was presented as the luminal area gain and measured by microscopy and image processing. The results show the increase of the grinding wheel size or rotational speed leads to a higher MRR and luminal gain in RA. With a 1.75 mm diameter grinding wheel rotating at 180,000 rpm in a 2 mm initial diameter lumen, the max MRR and the luminal gain are 2.49 mm2/(three passes) and 5.09 mm2, respectively. The MRR decreases as the number of grinding passes increases during RA with the same grinding wheel rotating at a constant speed. This study provides a thorough understanding of the wheel size and speed effects on RA MRR for improvements in RA devices and clinical operational guidelines.
{"title":"Experimental Investigation of the Calcified Plaque Material Removal Rate in Coronary Rotational Atherectomy","authors":"Xinxiao Li, Jiaqi Yang, Patrick Chernjavsky, Katerina Angjeli, Yang Liu, Yihao Zheng","doi":"10.1115/1.4063671","DOIUrl":"https://doi.org/10.1115/1.4063671","url":null,"abstract":"Abstract Rotational atherectomy (RA) is a minimally invasive procedure to remove the calcified atherosclerotic plaque from arteries to restore blood flow. It uses a high-speed, metal-bonded diamond abrasive grinding wheel to pulverize the calcified plaque into absorbable debris via a catheter through the artery. Although RA has been clinically used for over two decades, procedural complications persist and there remains a lack of consensus on the optimal device parameters. This study aims to investigate RA material removal rate (MRR) with respect to grinding wheel sizes and rotational speeds based on a tissue-mimicking phantom. Three grinding wheel sizes, 1.25, 1.5, and 1.75 mm in diameter, and three rotational speeds, 120,000, 150,000, and 180,000 rpm, were investigated. The RA MRR was presented as the luminal area gain and measured by microscopy and image processing. The results show the increase of the grinding wheel size or rotational speed leads to a higher MRR and luminal gain in RA. With a 1.75 mm diameter grinding wheel rotating at 180,000 rpm in a 2 mm initial diameter lumen, the max MRR and the luminal gain are 2.49 mm2/(three passes) and 5.09 mm2, respectively. The MRR decreases as the number of grinding passes increases during RA with the same grinding wheel rotating at a constant speed. This study provides a thorough understanding of the wheel size and speed effects on RA MRR for improvements in RA devices and clinical operational guidelines.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135254788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muh Anshar, Erni Marlina, Yossy Yoanita, Muhammad Ruslin, Dewiani Djamaluddin, Muhammad Arsyad Thaha, Muhammad Rusman, Andi Sitti Hajrah Yusuf
Abstract The present study aimed to report a novel developed technology for disinfecting pathogens in aerosols produced by dental health applications. The proposed method was integrated into a disinfection room installed inside an extraoral dental aerosol suction system. The experimental phase was designed to measure the application of the system during dental care management. These experiments assessed the effectiveness of the proposed mechanism in disinfecting captured microorganisms. The results showed that the system reduced the quantity and coverage area of harmful splatters and aerosols by ~50%. Future studies should verify the effectiveness of the approach for measuring the temperature inside the disinfection room and the number of pathogens, including coronavirus, that remains after the disinfection process.
{"title":"Assessment of a Novel Application of the Capture-Trap-Terminate Approach for Treating Aerosol Products During Dental Procedures","authors":"Muh Anshar, Erni Marlina, Yossy Yoanita, Muhammad Ruslin, Dewiani Djamaluddin, Muhammad Arsyad Thaha, Muhammad Rusman, Andi Sitti Hajrah Yusuf","doi":"10.1115/1.4063457","DOIUrl":"https://doi.org/10.1115/1.4063457","url":null,"abstract":"Abstract The present study aimed to report a novel developed technology for disinfecting pathogens in aerosols produced by dental health applications. The proposed method was integrated into a disinfection room installed inside an extraoral dental aerosol suction system. The experimental phase was designed to measure the application of the system during dental care management. These experiments assessed the effectiveness of the proposed mechanism in disinfecting captured microorganisms. The results showed that the system reduced the quantity and coverage area of harmful splatters and aerosols by ~50%. Future studies should verify the effectiveness of the approach for measuring the temperature inside the disinfection room and the number of pathogens, including coronavirus, that remains after the disinfection process.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":"199 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135307724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burr hole trepanation is a surgical procedure in which one or more small holes, or trephines, are made in the skull to allow for the drainage of fluids or to relieve pressure within the skull. Burr hole trepanation is generally considered a safe and effective treatment for conditions such as brain abscesses and subdural hematomas. However, the bone defects must be closed after the surgery with a suitable implant. Current designs are mostly based on bone plates with limited lifetime, revision access, and low aesthetic. Within this study, a new type of cranial implant is proposed made using additive manufacturing (AM) techniques. The implant is anchored in the burr hole and does not penetrate the skull space or prominate the skull. Four different types of implants have been proposed on the basis of an analytical model and verified using finite element analysis (FEA). New push-in mechanical tests are introduced using artificial bone to determine the strength of the locking mechanisms and ensure the safety of implants. The burr-hole implant with an overlap on the bone surface after implantation was proven to be the safest solution. The design of the new cranial implant can significantly improve the aesthetic outcome after surgery and minimize invasiveness in reoperations.
{"title":"Development And Mechanical Testing Of Implant For Cranial Reconstruction After Burr Hole Trepanation","authors":"Julia Bodnarova, Adam Kratochvil, Matej Daniel","doi":"10.1115/1.4063344","DOIUrl":"https://doi.org/10.1115/1.4063344","url":null,"abstract":"\u0000 Burr hole trepanation is a surgical procedure in which one or more small holes, or trephines, are made in the skull to allow for the drainage of fluids or to relieve pressure within the skull. Burr hole trepanation is generally considered a safe and effective treatment for conditions such as brain abscesses and subdural hematomas. However, the bone defects must be closed after the surgery with a suitable implant. Current designs are mostly based on bone plates with limited lifetime, revision access, and low aesthetic. Within this study, a new type of cranial implant is proposed made using additive manufacturing (AM) techniques. The implant is anchored in the burr hole and does not penetrate the skull space or prominate the skull. Four different types of implants have been proposed on the basis of an analytical model and verified using finite element analysis (FEA). New push-in mechanical tests are introduced using artificial bone to determine the strength of the locking mechanisms and ensure the safety of implants. The burr-hole implant with an overlap on the bone surface after implantation was proven to be the safest solution. The design of the new cranial implant can significantly improve the aesthetic outcome after surgery and minimize invasiveness in reoperations.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43064307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Although laparoscopy has revolutionized modern medicine, its training remains long and complex due to reduced haptic feedback and loss of depth perception. Training also poses an ethical challenge when performed on living patients, and access to cadavers is becoming rare and difficult. In the early 2000s, medical simulators began to appear to help mitigate these problems: virtual reality simulators (VRS) and physical reality simulators (PRS). Current VRS can provide guidance and performance evaluation with fewer instructors but are expensive and bulky. PRS, on the other hand, are less expensive, compact and offer haptic feedback through real physical interactions with mockup objects. However, they require guidance from an instructor, and cannot provide objective assessment or complex and realistic surgical scenarios. This paper assesses the potential of a VRS based on magneto-rheological (MR) actuators that could offer the haptic capabilities of current VRS with the size envelopes of PRS. Technical specifications for a laparoscopic VRS are extracted from the literature, a prototype is built and evaluated experimentally. In addition, three simulation scenarios are built and presented to surgeons to confirm simulation capabilities. In its current form, the MR-powered prototype is shown to meet targeted functional specifications but future work is needed to reduce friction, reduce size, and optimize packaging.
{"title":"Preliminary Assessment of a Laparoscopic Training System Using Magneto-Rheological Clutches and Virtual Reality","authors":"Bruno-Pier Busque, Louis-Philippe Lebel, Yves Collin, Jean-Sébastien Plante","doi":"10.1115/1.4063389","DOIUrl":"https://doi.org/10.1115/1.4063389","url":null,"abstract":"Abstract Although laparoscopy has revolutionized modern medicine, its training remains long and complex due to reduced haptic feedback and loss of depth perception. Training also poses an ethical challenge when performed on living patients, and access to cadavers is becoming rare and difficult. In the early 2000s, medical simulators began to appear to help mitigate these problems: virtual reality simulators (VRS) and physical reality simulators (PRS). Current VRS can provide guidance and performance evaluation with fewer instructors but are expensive and bulky. PRS, on the other hand, are less expensive, compact and offer haptic feedback through real physical interactions with mockup objects. However, they require guidance from an instructor, and cannot provide objective assessment or complex and realistic surgical scenarios. This paper assesses the potential of a VRS based on magneto-rheological (MR) actuators that could offer the haptic capabilities of current VRS with the size envelopes of PRS. Technical specifications for a laparoscopic VRS are extracted from the literature, a prototype is built and evaluated experimentally. In addition, three simulation scenarios are built and presented to surgeons to confirm simulation capabilities. In its current form, the MR-powered prototype is shown to meet targeted functional specifications but future work is needed to reduce friction, reduce size, and optimize packaging.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135248680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The present study proposes a novel model that establishes the relationship between the bending moment and the curvature of a steerable catheter. The catheters exhibit a nonlinear viscoelastic tendency, so the moment-curvature relationship is modeled as a bending of a quasilinear viscoelastic (QLV) cantilever beam. Stress relaxation tests with multiple magnitudes are performed on a catheter, and the parameter tuning is carried out with the test results to find out the coefficients of the model. The form of the instantaneous moment response, which is an important term within the QLV equation, is selected as a logarithmic form by analyzing the test results. This differentiates the accuracy of the model from using the commonly used exponential form. The performance of the logarithmic QLV model is compared to the conventional models by checking the curvature range each model can cover with a certain accuracy. The covering range for elastic, linear viscoelastic, and exponential QLV models are 22.1%, 64.4%, and 55.5%, respectively, whereas the covering range of the logarithmic QLV model is 100%.
{"title":"A Novel Quasilinear Viscoelastic Model of the Bending of a Steerable Catheter","authors":"Jajun Ryu, Jung-Hwa Ahn, Hwa-Young Kim","doi":"10.1115/1.4063215","DOIUrl":"https://doi.org/10.1115/1.4063215","url":null,"abstract":"\u0000 The present study proposes a novel model that establishes the relationship between the bending moment and the curvature of a steerable catheter. The catheters exhibit a nonlinear viscoelastic tendency, so the moment-curvature relationship is modeled as a bending of a quasilinear viscoelastic (QLV) cantilever beam. Stress relaxation tests with multiple magnitudes are performed on a catheter, and the parameter tuning is carried out with the test results to find out the coefficients of the model. The form of the instantaneous moment response, which is an important term within the QLV equation, is selected as a logarithmic form by analyzing the test results. This differentiates the accuracy of the model from using the commonly used exponential form. The performance of the logarithmic QLV model is compared to the conventional models by checking the curvature range each model can cover with a certain accuracy. The covering range for elastic, linear viscoelastic, and exponential QLV models are 22.1%, 64.4%, and 55.5%, respectively, whereas the covering range of the logarithmic QLV model is 100%.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47514965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kathryn R Marusich, N. Harel, Matthew D. Johnson, Paul Rothweiler, A. Erdman
Deep brain stimulation (DBS) is a treatment for several neurological disorders including Parkinson's Disease, Essential tremor, and Epilepsy. The neurosurgical procedure involves implanting a lead of electrodes to a deep brain target and thereafter electrically stimulating that target to suppress symptoms. To reduce the probability of intracranial bleeding during implantation, neurosurgeons carefully plan out a patient-specific lead trajectory that avoids passing the lead through regions with major blood vessels. This process can be tedious, and there is a need to provide neurosurgeons with a more efficient and quantitative means to identify major blood vessels on a patient specific basis. Here, we developed a modular graphical user interface (GUI) containing anatomically segmented digital reconstructions of patient vasculature, cortex, and deep brain target anatomy from preoperative high-field (3T and 7T) MRI. The system prompts users to identify the deep brain target, and then algorithmically calculates a log-scale blood vessel density along the length of potential lead trajectories that pivot around the deep brain target. Heatmaps highlighting regions with low blood vessel density were calculated for cortical and subcortical vasculature models. The modeling framework enabled users to further interact with the models by panning, rotating, zooming, showing, or hiding the various anatomical reconstructions and heatmaps. Providing surgeons with quantitative, patient specific vasculature data has potential to further reduce the likelihood of hemorrhage events during microelectrode mapping and DBS lead implantation.
{"title":"Trajectory Planning Software for Deep Brain Stimulation Driven by Patient Specific Data","authors":"Kathryn R Marusich, N. Harel, Matthew D. Johnson, Paul Rothweiler, A. Erdman","doi":"10.1115/1.4063142","DOIUrl":"https://doi.org/10.1115/1.4063142","url":null,"abstract":"\u0000 Deep brain stimulation (DBS) is a treatment for several neurological disorders including Parkinson's Disease, Essential tremor, and Epilepsy. The neurosurgical procedure involves implanting a lead of electrodes to a deep brain target and thereafter electrically stimulating that target to suppress symptoms. To reduce the probability of intracranial bleeding during implantation, neurosurgeons carefully plan out a patient-specific lead trajectory that avoids passing the lead through regions with major blood vessels. This process can be tedious, and there is a need to provide neurosurgeons with a more efficient and quantitative means to identify major blood vessels on a patient specific basis. Here, we developed a modular graphical user interface (GUI) containing anatomically segmented digital reconstructions of patient vasculature, cortex, and deep brain target anatomy from preoperative high-field (3T and 7T) MRI. The system prompts users to identify the deep brain target, and then algorithmically calculates a log-scale blood vessel density along the length of potential lead trajectories that pivot around the deep brain target. Heatmaps highlighting regions with low blood vessel density were calculated for cortical and subcortical vasculature models. The modeling framework enabled users to further interact with the models by panning, rotating, zooming, showing, or hiding the various anatomical reconstructions and heatmaps. Providing surgeons with quantitative, patient specific vasculature data has potential to further reduce the likelihood of hemorrhage events during microelectrode mapping and DBS lead implantation.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42334249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Pasaguayo, Z. Al Masry, Sergio Lescano, N. Zerhouni
This review article provides an overview of some challenges that arise when developing new medical robotic microgrippers. The main challenges are due to miniaturization and are present in the manufacturing and assembly processes, the types of mechanisms, the biomaterials used, the actuation principles, and the compliance with some standards and regulations. The main medical fields where these microgrippers are used are in MIS and biomedical applications. Therefore, taking these two large groups into account, this review presents a microgrippers classification according to the type of mechanism used (traditional rigid-body mechanisms and complaint mechanisms). Moreover, parameters such as applications, functionalities, DOF, sizes, range of motion, biomaterial used, and proposed methods are highlighted. In total, the analysis of 21 microgrippers among commercial and developed by research institutes is presented.
{"title":"Surgical Microgrippers: A Survey And Analysis","authors":"L. Pasaguayo, Z. Al Masry, Sergio Lescano, N. Zerhouni","doi":"10.1115/1.4062950","DOIUrl":"https://doi.org/10.1115/1.4062950","url":null,"abstract":"\u0000 This review article provides an overview of some challenges that arise when developing new medical robotic microgrippers. The main challenges are due to miniaturization and are present in the manufacturing and assembly processes, the types of mechanisms, the biomaterials used, the actuation principles, and the compliance with some standards and regulations. The main medical fields where these microgrippers are used are in MIS and biomedical applications. Therefore, taking these two large groups into account, this review presents a microgrippers classification according to the type of mechanism used (traditional rigid-body mechanisms and complaint mechanisms). Moreover, parameters such as applications, functionalities, DOF, sizes, range of motion, biomaterial used, and proposed methods are highlighted. In total, the analysis of 21 microgrippers among commercial and developed by research institutes is presented.","PeriodicalId":49305,"journal":{"name":"Journal of Medical Devices-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46612500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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