Pub Date : 2026-01-01DOI: 10.1016/j.soard.2025.10.001
Salvatore Docimo Jr. D.O., M.B.A. , Rodolfo J. Oviedo M.D. , Cheguevara Afaneh M.D. , Bruce Schirmer M.D. , Fady Moustarah M.D. , Karen Grothe Ph.D. , R.Wesley Vosburg M.D. , Jonathan Carter M.D. , Clinical Issues Committee of the American Society for Metabolic and Bariatric Surgery
Background
Endoscopic bariatrics is a growing area of interest in the battle against obesity. This systematic review provides a review of the pertinent endoluminal approaches to bariatrics. The purpose of this review is to describe the current indications, clinical outcomes, safety profile, and the progress of endoluminal bariatric therapies for both primary and revisional indications.
Methods
We conducted a systematic review based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). A review of databases were performed and all studies were then evaluated based on inclusion and exclusion criteria: all studies with participants over the age of 18 years, a meta-analysis design, a randomized trial design, or a cohort study design were included. All case reports, letters, comments, and animal and in vitro studies were excluded.
Results
A total of 9586 articles were retrieved from our search. After removing duplicates, 7778 studies remained. After applying inclusion and exclusion criteria, and adding one study from our review of citations, a total of 46 studies were included in our study (Fig. 1).
Discussion
This review was conducted utilizing all aspects of the PRISMA model for systematic review. The 46 studies included summaries the various approaches to endoluminal bariatrics and provides a thorough overview of outcomes and complications.
{"title":"American Society for Metabolic and Bariatric Surgery review of endobariatric procedures","authors":"Salvatore Docimo Jr. D.O., M.B.A. , Rodolfo J. Oviedo M.D. , Cheguevara Afaneh M.D. , Bruce Schirmer M.D. , Fady Moustarah M.D. , Karen Grothe Ph.D. , R.Wesley Vosburg M.D. , Jonathan Carter M.D. , Clinical Issues Committee of the American Society for Metabolic and Bariatric Surgery","doi":"10.1016/j.soard.2025.10.001","DOIUrl":"10.1016/j.soard.2025.10.001","url":null,"abstract":"<div><h3>Background</h3><div>Endoscopic bariatrics is a growing area of interest in the battle against obesity. This systematic review provides a review of the pertinent endoluminal approaches to bariatrics. The purpose of this review is to describe the current indications, clinical outcomes, safety profile, and the progress of endoluminal bariatric therapies for both primary and revisional indications.</div></div><div><h3>Methods</h3><div>We conducted a systematic review based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). A review of databases were performed and all studies were then evaluated based on inclusion and exclusion criteria: all studies with participants over the age of 18 years, a meta-analysis design, a randomized trial design, or a cohort study design were included. All case reports, letters, comments, and animal and in vitro studies were excluded.</div></div><div><h3>Results</h3><div>A total of 9586 articles were retrieved from our search. After removing duplicates, 7778 studies remained. After applying inclusion and exclusion criteria, and adding one study from our review of citations, a total of 46 studies were included in our study (Fig. 1).</div></div><div><h3>Discussion</h3><div>This review was conducted utilizing all aspects of the PRISMA model for systematic review. The 46 studies included summaries the various approaches to endoluminal bariatrics and provides a thorough overview of outcomes and complications.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 1-17"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145508744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.soard.2025.11.014
Nicole L. Petcka M.D., Elizabeth M. Hechenbleikner M.D.
{"title":"Comment on: kidney transplantation after bariatric surgery – outcomes from a 30-year experience","authors":"Nicole L. Petcka M.D., Elizabeth M. Hechenbleikner M.D.","doi":"10.1016/j.soard.2025.11.014","DOIUrl":"10.1016/j.soard.2025.11.014","url":null,"abstract":"","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 65-66"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145663173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutritional deficiencies are frequent after metabolic and bariatric surgery (MBS) and systematic addition of vitamin B12, iron, calcium, and vitamin D to standard multivitamin tablets is recommended. However, there are still uncertainties because supporting data are few and compliance with a large number of tablets is low.
Objectives
To assess the need for additional supplements using a supplementation based on biological assays after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG).
Methods
Consecutive patients (N = 313: 179 RYGB/134 SG; 86% women, mean age 44.1 ± 10.3 years, Body mass index 43.5 ± 6.6 kg/m2) who underwent a nutritional assessment, before and at 6, 12, and 36 months after MBS, were studied. Multivitamin tablets were systematically prescribed after MBS, and additional supplements were introduced following a standardized protocol in the case of deficiency.
Setting
University Hospital, France.
Results
Although the number of patients taking additional supplements increased by more after RYGB than after SG (58.7% vs 43.3%, P < .01), the mean number of deficits did not increase and was similar at 3 years (3.7 vs 3.4, Ns). The frequency of nutritional symptoms was also similar after both procedures, the most common being hair loss, while neurological symptoms were unusual and mild. Anemia was infrequent, but secondary hyperparathyroidism was frequent after RYGB (23% vs 9% after SG, P < .01).
Conclusions
A personalized supplementation strategy adapted to biological parameters, in patients followed regularly up to 3 years after MBS, may reduce the number of nutritional supplements without increasing the number of deficiencies. However, vigilance must be maintained, particularly regarding bone and neurological risks.
背景:代谢和减肥手术(MBS)后经常出现营养缺乏,建议在标准复合维生素片中系统添加维生素B12、铁、钙和维生素D。然而,由于支持数据很少,并且大量平板电脑的依从性很低,因此仍然存在不确定性。目的:评估Roux-en-Y胃旁路(RYGB)和袖式胃切除术(SG)后使用基于生物测定的补充物的额外补充的必要性。方法:研究连续患者(N = 313: 179 RYGB/134 SG; 86%女性,平均年龄44.1±10.3岁,体重指数43.5±6.6 kg/m2),在MBS之前和6、12和36个月后进行营养评估。在MBS后系统地开了复合维生素片,在缺乏的情况下,根据标准化的方案引入了额外的补充剂。地点:法国大学医院。结果:尽管RYGB后服用额外补充剂的患者数量比SG后增加更多(58.7% vs 43.3%, P < 0.01),但平均缺陷数没有增加,并且在3年内相似(3.7 vs 3.4, Ns)。两种手术后出现营养症状的频率也相似,最常见的是脱发,而神经症状不寻常且轻微。贫血不常见,但RYGB术后继发性甲状旁腺功能亢进发生率较高(23% vs 9%, P < 0.01)。结论:在MBS后定期随访3年的患者中,适应生物学参数的个性化补充策略可能会减少营养补充的数量,而不会增加缺乏症的数量。然而,必须保持警惕,特别是对骨骼和神经系统的风险。
{"title":"Pragmatic strategy for vitamin and micronutrient supplementation after metabolic and bariatric surgery","authors":"Hélène Chappard M.D. , Ouidad Sami M.D. , Imen Sakka M.D. , Suzette Coelho , Thierry Dupré M.D. , Muriel Coupaye M.D. , David Moszkowicz M.D., Ph.D. , Séverine Ledoux M.D., Ph.D.","doi":"10.1016/j.soard.2025.08.023","DOIUrl":"10.1016/j.soard.2025.08.023","url":null,"abstract":"<div><h3>Background</h3><div>Nutritional deficiencies are frequent after metabolic and bariatric surgery (MBS) and systematic addition of vitamin B12, iron, calcium, and vitamin D to standard multivitamin tablets is recommended. However, there are still uncertainties because supporting data are few and compliance with a large number of tablets is low.</div></div><div><h3>Objectives</h3><div>To assess the need for additional supplements using a supplementation based on biological assays after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG).</div></div><div><h3>Methods</h3><div>Consecutive patients (N = 313: 179 RYGB/134 SG; 86% women, mean age 44.1 ± 10.3 years, Body mass index 43.5 ± 6.6 kg/m<sup>2</sup>) who underwent a nutritional assessment, before and at 6, 12, and 36 months after MBS, were studied. Multivitamin tablets were systematically prescribed after MBS, and additional supplements were introduced following a standardized protocol in the case of deficiency.</div></div><div><h3>Setting</h3><div>University Hospital, France.</div></div><div><h3>Results</h3><div>Although the number of patients taking additional supplements increased by more after RYGB than after SG (58.7% vs 43.3%, <em>P</em> < .01), the mean number of deficits did not increase and was similar at 3 years (3.7 vs 3.4, Ns). The frequency of nutritional symptoms was also similar after both procedures, the most common being hair loss, while neurological symptoms were unusual and mild. Anemia was infrequent, but secondary hyperparathyroidism was frequent after RYGB (23% vs 9% after SG, <em>P</em> < .01).</div></div><div><h3>Conclusions</h3><div>A personalized supplementation strategy adapted to biological parameters, in patients followed regularly up to 3 years after MBS, may reduce the number of nutritional supplements without increasing the number of deficiencies. However, vigilance must be maintained, particularly regarding bone and neurological risks.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 67-75"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.soard.2025.09.011
Flora I. Kartnig M.D. , Marlene Prager M.D. , Carsten T. Herz M.D. , Oana C. Kulterer M.D., Ph.D. , Elaine M. Khoshmehr , Rita Horodecki-Tucheslau M.D. , Michael R. Krebs M.D. , Gerhard Prager M.D. , Alexandra Kautzky-Willer M.D. , Florian W. Kiefer M.D., Ph.D.
Background
Obesity is linked to increased risk of cardiovascular disease, type 2 diabetes, and overall mortality. Bariatric surgery effectively achieves long-term weight loss, especially in clinically severe obesity. Postoperative weight loss is associated with increased N-terminal pro B-type natriuretic peptide (NT-proBNP) levels, without signs of cardiac dysfunction.
Objectives
We investigated longitudinal changes in NT-proBNP levels following different bariatric procedures and examined their associations with metabolic alterations.
Setting
This retrospective study was conducted in a large university hospital in central Europe using data from 2005 to 2016.
Methods
We analyzed preoperative and postoperative laboratory results from 508 patients undergoing three different bariatric procedures. Follow-up records were available for 347 (68.3%) patients at month 3, 260 (51.2%) at month 6, 152 (29.9%) at month 9, 183 (36.0%) at month 12, 166 (32.7%) at month 18, and 127 (25.0%) at month 24 postsurgery.
Results
NT-proBNP levels rose shortly after bariatric surgery and remained elevated, with no significant differences between surgical types. Women exhibited significantly higher postoperative NT-proBNP concentrations than men. The increase in NT-proBNP correlated with improved insulin resistance but not with other metabolic parameters. We found no evidence supporting reduced renal clearance as a cause for elevated natriuretic peptides.
Conclusions
Our data suggest a link between the NT-proBNP increase and reduced hyperinsulinemia following bariatric surgery, offering new insights into mechanisms underlying this frequent postoperative finding.
{"title":"N-terminal pro B-type natriuretic peptide increase after bariatric surgery is linked to decreased insulin resistance and is more pronounced in women","authors":"Flora I. Kartnig M.D. , Marlene Prager M.D. , Carsten T. Herz M.D. , Oana C. Kulterer M.D., Ph.D. , Elaine M. Khoshmehr , Rita Horodecki-Tucheslau M.D. , Michael R. Krebs M.D. , Gerhard Prager M.D. , Alexandra Kautzky-Willer M.D. , Florian W. Kiefer M.D., Ph.D.","doi":"10.1016/j.soard.2025.09.011","DOIUrl":"10.1016/j.soard.2025.09.011","url":null,"abstract":"<div><h3>Background</h3><div>Obesity is linked to increased risk of cardiovascular disease, type 2 diabetes, and overall mortality. Bariatric surgery effectively achieves long-term weight loss, especially in clinically severe obesity. Postoperative weight loss is associated with increased N-terminal pro B-type natriuretic peptide (NT-proBNP) levels, without signs of cardiac dysfunction.</div></div><div><h3>Objectives</h3><div>We investigated longitudinal changes in NT-proBNP levels following different bariatric procedures and examined their associations with metabolic alterations.</div></div><div><h3>Setting</h3><div>This retrospective study was conducted in a large university hospital in central Europe using data from 2005 to 2016.</div></div><div><h3>Methods</h3><div>We analyzed preoperative and postoperative laboratory results from 508 patients undergoing three different bariatric procedures. Follow-up records were available for 347 (68.3%) patients at month 3, 260 (51.2%) at month 6, 152 (29.9%) at month 9, 183 (36.0%) at month 12, 166 (32.7%) at month 18, and 127 (25.0%) at month 24 postsurgery.</div></div><div><h3>Results</h3><div>NT-proBNP levels rose shortly after bariatric surgery and remained elevated, with no significant differences between surgical types. Women exhibited significantly higher postoperative NT-proBNP concentrations than men. The increase in NT-proBNP correlated with improved insulin resistance but not with other metabolic parameters. We found no evidence supporting reduced renal clearance as a cause for elevated natriuretic peptides.</div></div><div><h3>Conclusions</h3><div>Our data suggest a link between the NT-proBNP increase and reduced hyperinsulinemia following bariatric surgery, offering new insights into mechanisms underlying this frequent postoperative finding.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 106-112"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.soard.2025.09.014
Hila Zelicha R.D., Ph.D. , Zachary N. Weitzner M.D. , Seuna Park N.P. , Tony G. Babb Ph.D. , Vipa Bernhardt Ph.D. , Faraz S. Ahmad M.D., M.S. , David Cella Ph.D. , Yijun Chen M.D. , Edward H. Livingston M.D.
Background
There is a need for an instrument that efficiently identifies heart failure (HF) symptoms in patients with obesity.
Objectives
To determine the spectrum of HF symptoms in patients with severe obesity who lose weight following bariatric surgery using a new, validated HF health-related quality of life (HRQOL) instrument, Patient-Reported Outcomes Measurement Information System (PROMIS) + HF-27.
Setting
Health academic quaternary care center in the United States.
Methods
Prospective longitudinal 12-month cohort study. PROMIS + HF-27 HRQOL surveys were administered before and 1 year after sleeve gastrectomy. T-scores anchoring HRQOL domain scores to the U.S. general population were calculated. Dyspnea T-scores were centered on a chronic obstructive pulmonary disease reference population.
Results
Of 40 patients at baseline, 33 (83%) reported some degree of dyspnea: mild n = 18 (55%), moderate n = 12 (36%), and severe n = 3 (9%) on the PROMIS + HF-27 survey. Only 1 patient had been given a clinical diagnosis of dyspnea during routine primary care visits. Dyspnea, physical function, fatigue, sleep disorders, and pain T-scores were significantly improved (dyspnea: preoperative: 45.3 ± 8.2, postoperative: 35.6 ± 4.9, P < .0001; physical function: preoperative: 47.7 ± 7.6, postoperative: 52.3 ± 5.3, P = .001; fatigue: preoperative: 54.5 ± 8.6, postoperative: 45.7 ± 8.1, P < .000; sleep disorders: preoperative: 52.1 ± 8.5, postoperative: 46.6 ± 7.8, P = .002; pain: preoperative: 55.1 ± 9.4, postoperative: 47.3 ± 6.2, P < .0001; n = 40). Depression and cognitive disturbances T-scores did not significantly change after surgery (P > .05 for all). Summary scores for physical function, social roles, mental function, and the overall HRQOL total score were significantly improved 1 year after bariatric surgery (P < .05). None of the summary scores or the domain T-scores, including dyspnea, were significantly associated with weight loss adjusted for sex, age, and preoperative weight.
Conclusions
PROMIS + HF-27 efficiently measured and detected improvements in multiple obesity-relevant HRQOL domains following sleeve gastrectomy. Of these, dyspnea was the most prominent and showed the largest improvement after bariatric surgery.
{"title":"Improvement in breathlessness following bariatric surgery as measured by a new heart failure–specific health-related quality of life instrument: a prospective longitudinal study","authors":"Hila Zelicha R.D., Ph.D. , Zachary N. Weitzner M.D. , Seuna Park N.P. , Tony G. Babb Ph.D. , Vipa Bernhardt Ph.D. , Faraz S. Ahmad M.D., M.S. , David Cella Ph.D. , Yijun Chen M.D. , Edward H. Livingston M.D.","doi":"10.1016/j.soard.2025.09.014","DOIUrl":"10.1016/j.soard.2025.09.014","url":null,"abstract":"<div><h3>Background</h3><div>There is a need for an instrument that efficiently identifies heart failure (HF) symptoms in patients with obesity.</div></div><div><h3>Objectives</h3><div>To determine the spectrum of HF symptoms in patients with severe obesity who lose weight following bariatric surgery using a new, validated HF health-related quality of life (HRQOL) instrument, Patient-Reported Outcomes Measurement Information System (PROMIS) + HF-27.</div></div><div><h3>Setting</h3><div>Health academic quaternary care center in the United States.</div></div><div><h3>Methods</h3><div>Prospective longitudinal 12-month cohort study. PROMIS + HF-27 HRQOL surveys were administered before and 1 year after sleeve gastrectomy. T-scores anchoring HRQOL domain scores to the U.S. general population were calculated. Dyspnea T-scores were centered on a chronic obstructive pulmonary disease reference population.</div></div><div><h3>Results</h3><div>Of 40 patients at baseline, 33 (83%) reported some degree of dyspnea: mild n = 18 (55%), moderate n = 12 (36%), and severe n = 3 (9%) on the PROMIS + HF-27 survey. Only 1 patient had been given a clinical diagnosis of dyspnea during routine primary care visits. Dyspnea, physical function, fatigue, sleep disorders, and pain T-scores were significantly improved (dyspnea: preoperative: 45.3 ± 8.2, postoperative: 35.6 ± 4.9, <em>P</em> < .0001; physical function: preoperative: 47.7 ± 7.6, postoperative: 52.3 ± 5.3, <em>P</em> = .001; fatigue: preoperative: 54.5 ± 8.6, postoperative: 45.7 ± 8.1, <em>P</em> < .000; sleep disorders: preoperative: 52.1 ± 8.5, postoperative: 46.6 ± 7.8, <em>P</em> = .002; pain: preoperative: 55.1 ± 9.4, postoperative: 47.3 ± 6.2, <em>P</em> < .0001; n = 40). Depression and cognitive disturbances T-scores did not significantly change after surgery (<em>P</em> > .05 for all). Summary scores for physical function, social roles, mental function, and the overall HRQOL total score were significantly improved 1 year after bariatric surgery (<em>P</em> < .05). None of the summary scores or the domain T-scores, including dyspnea, were significantly associated with weight loss adjusted for sex, age, and preoperative weight.</div></div><div><h3>Conclusions</h3><div>PROMIS + HF-27 efficiently measured and detected improvements in multiple obesity-relevant HRQOL domains following sleeve gastrectomy. Of these, dyspnea was the most prominent and showed the largest improvement after bariatric surgery.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 137-144"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145531046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.soard.2025.11.001
Sean M. O’Neill M.D., Ph.D., Ryan A. Howard M.D., Hope T. Jackson M.D.
{"title":"Comment on: “Effects of neoadjuvant glucagon-like-peptide 1 receptor agonists on weight loss after bariatric surgery”","authors":"Sean M. O’Neill M.D., Ph.D., Ryan A. Howard M.D., Hope T. Jackson M.D.","doi":"10.1016/j.soard.2025.11.001","DOIUrl":"10.1016/j.soard.2025.11.001","url":null,"abstract":"","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 24-25"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.soard.2025.07.015
Gail A. Kerver Ph.D. , Kristine J. Steffen Pharm.D., Ph.D. , Glen Forester Ph.D. , Leslie A. Laam Ph.D. , Sugong Chen M.D. , Ellen Vogels D.O. , David B. Sarwer Ph.D. , Stephen A. Wonderlich Ph.D. , Scott G. Engel Ph.D.
Background
Hypoglycemia (i.e., low blood glucose) is a potential complication following metabolic and bariatric surgery (MBS) that can ultimately result in severe and deadly consequences. However, the symptoms typically associated with hypoglycemia (e.g., dizziness, anxiety) can be nonspecific, which impairs effective monitoring.
Objectives
This study utilized a unique combination of naturalistic assessments to compare the subjective self-report of hypoglycemic symptoms measured via ecological momentary assessment (EMA) with objectively-collected data from continuous glucose monitoring (CGM).
Setting
Private Hospital, United States.
Methods
Participants were 44 adults who completed 10 days of EMA and CGM 1 year after undergoing Roux-en-Y gastric bypass. Multiple times per day during the EMA protocol, participants identified how many of 18 hypoglycemic symptoms they had experienced since they were last signaled several hours earlier.
Results
CGM data showed that ∼66% of participants experienced at least one possible daytime hypoglycemic event (range = 1-23 episodes/person). The total number of hypoglycemic symptoms endorsed via EMA did not correspond with the occurrence of a possible hypoglycemic event captured by CGM (P = .145). However, multilevel models revealed that participants were more likely to report feeling “shaky”, “lightheaded”, and “coordination problems/clumsiness” (false discovery rate corrected P values < .05) during periods of time coinciding with possible hypoglycemic events identified by CGM.
Conclusions
Many patients are at risk for low blood glucose post-MBS. In the absence of objective assessment, several subjective symptoms may serve as indicators of possible hypoglycemic events following MBS.
{"title":"Hypoglycemia following metabolic and bariatric surgery: evidence from objective and subjective naturalistic assessment methods","authors":"Gail A. Kerver Ph.D. , Kristine J. Steffen Pharm.D., Ph.D. , Glen Forester Ph.D. , Leslie A. Laam Ph.D. , Sugong Chen M.D. , Ellen Vogels D.O. , David B. Sarwer Ph.D. , Stephen A. Wonderlich Ph.D. , Scott G. Engel Ph.D.","doi":"10.1016/j.soard.2025.07.015","DOIUrl":"10.1016/j.soard.2025.07.015","url":null,"abstract":"<div><h3>Background</h3><div>Hypoglycemia (i.e., low blood glucose) is a potential complication following metabolic and bariatric surgery (MBS) that can ultimately result in severe and deadly consequences. However, the symptoms typically associated with hypoglycemia (e.g., dizziness, anxiety) can be nonspecific, which impairs effective monitoring.</div></div><div><h3>Objectives</h3><div>This study utilized a unique combination of naturalistic assessments to compare the subjective self-report of hypoglycemic symptoms measured via ecological momentary assessment (EMA) with objectively-collected data from continuous glucose monitoring (CGM).</div></div><div><h3>Setting</h3><div>Private Hospital, United States.</div></div><div><h3>Methods</h3><div>Participants were 44 adults who completed 10 days of EMA and CGM 1 year after undergoing Roux-en-Y gastric bypass. Multiple times per day during the EMA protocol, participants identified how many of 18 hypoglycemic symptoms they had experienced since they were last signaled several hours earlier.</div></div><div><h3>Results</h3><div>CGM data showed that ∼66% of participants experienced at least one possible daytime hypoglycemic event (range = 1-23 episodes/person). The total number of hypoglycemic symptoms endorsed via EMA did not correspond with the occurrence of a possible hypoglycemic event captured by CGM (<em>P</em> = .145). However, multilevel models revealed that participants were more likely to report feeling “shaky”, “lightheaded”, and “coordination problems/clumsiness” (false discovery rate corrected <em>P</em> values < .05) during periods of time coinciding with possible hypoglycemic events identified by CGM.</div></div><div><h3>Conclusions</h3><div>Many patients are at risk for low blood glucose post-MBS. In the absence of objective assessment, several subjective symptoms may serve as indicators of possible hypoglycemic events following MBS.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 157-163"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.soard.2025.08.026
Scott G. Engel Ph.D. , Stephen A. Wonderlich Ph.D. , Debra Safer M.D. , Gail A. Kerver Ph.D. , Leslie A. Laam Ph.D. , Ross D. Crosby Ph.D. , Katherine Nameth B.S. , Leslie J. Heinberg Ph.D. , Dale Bond Ph.D. , Kristine J. Steffen Pharm.D., Ph.D.
Background
There is considerable variability in both the timing of weight change and changes in psychological difficulties functioning following metabolic bariatric surgery (MBS). Empirical studies appear to show that levels of depressive symptoms decrease with weight loss and increase due to weight recurrence. Yet, this research has not included sufficient repeated measurements to account for individual differences in the timing of when weight nadir is achieved and weight recurrence begins post-MBS.
Objectives
Examine how trait-like measures of mood and momentary measures of affect change over time relative to when an individual reach their nadir weight following MBS.
Setting
A health care facility in Sanford Research, Fargo, ND and a university health care facility in Stanford University, Stanford, CA.
Methods
Participants provided data from before surgery until 3 years after surgery. Depressive symptoms (as measured by the Beck Depressive symptoms Inventory) and weight were collected during in-person visits at 6-, 12-, 15-, 18-, 21-, 24-, 30-, and 36-months postsurgery. Momentary mood was assessed via ecologic momentary assessment at 1, 2, and 3 years after surgery.
Results
No difference in BDI scores emerged relative to weight nadir (both before and after nadir). However, there was a statistically-significant positive association between time in months relative to weight nadir and momentary negative affect, but this effect was quite small.
Conclusions
The current study suggests that depressive symptoms does not improve in the time between MBS and weight nadir (i.e., weight loss phase) and also does not deteriorate meaningfully after patients reach their weight nadir (i.e., weight recurrence phase). While momentary negative affect was related to weight change after surgery, this small effect is not likely clinically meaningful.
{"title":"Will metabolic bariatric surgery improve my patient’s mood? A careful examination of the relationship between mood, negative affect, and weight loss and recurrence after surgery","authors":"Scott G. Engel Ph.D. , Stephen A. Wonderlich Ph.D. , Debra Safer M.D. , Gail A. Kerver Ph.D. , Leslie A. Laam Ph.D. , Ross D. Crosby Ph.D. , Katherine Nameth B.S. , Leslie J. Heinberg Ph.D. , Dale Bond Ph.D. , Kristine J. Steffen Pharm.D., Ph.D.","doi":"10.1016/j.soard.2025.08.026","DOIUrl":"10.1016/j.soard.2025.08.026","url":null,"abstract":"<div><h3>Background</h3><div>There is considerable variability in both the timing of weight change and changes in psychological difficulties functioning following metabolic bariatric surgery (MBS). Empirical studies appear to show that levels of depressive symptoms decrease with weight loss and increase due to weight recurrence. Yet, this research has not included sufficient repeated measurements to account for individual differences in the timing of when weight nadir is achieved and weight recurrence begins post-MBS.</div></div><div><h3>Objectives</h3><div>Examine how trait-like measures of mood and momentary measures of affect change over time relative to when an individual reach their nadir weight following MBS.</div></div><div><h3>Setting</h3><div>A health care facility in Sanford Research, Fargo, ND and a university health care facility in Stanford University, Stanford, CA.</div></div><div><h3>Methods</h3><div>Participants provided data from before surgery until 3 years after surgery. Depressive symptoms (as measured by the Beck Depressive symptoms Inventory) and weight were collected during in-person visits at 6-, 12-, 15-, 18-, 21-, 24-, 30-, and 36-months postsurgery. Momentary mood was assessed via ecologic momentary assessment at 1, 2, and 3 years after surgery.</div></div><div><h3>Results</h3><div>No difference in BDI scores emerged relative to weight nadir (both before and after nadir). However, there was a statistically-significant positive association between time in months relative to weight nadir and momentary negative affect, but this effect was quite small.</div></div><div><h3>Conclusions</h3><div>The current study suggests that depressive symptoms does not improve in the time between MBS and weight nadir (i.e., weight loss phase) and also does not deteriorate meaningfully after patients reach their weight nadir (i.e., weight recurrence phase). While momentary negative affect was related to weight change after surgery, this small effect is not likely clinically meaningful.</div></div>","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 145-150"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145461039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on “unveiling the cost-effectiveness of bariatric surgery: insights from a matched cohort study”","authors":"Gita Venkata Siva Maruthi Alluri, Koyel Roy, Sunil","doi":"10.1016/j.soard.2025.08.018","DOIUrl":"10.1016/j.soard.2025.08.018","url":null,"abstract":"","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 181-182"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145484425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.soard.2025.11.005
Mélissa V. Wills M.D., Matthew Kroh M.D.
{"title":"Comment on: “Achieving optimal nutritional goals in management of patients with sleeve gastrectomy leaks with endoluminal vacuum therapy”","authors":"Mélissa V. Wills M.D., Matthew Kroh M.D.","doi":"10.1016/j.soard.2025.11.005","DOIUrl":"10.1016/j.soard.2025.11.005","url":null,"abstract":"","PeriodicalId":49462,"journal":{"name":"Surgery for Obesity and Related Diseases","volume":"22 1","pages":"Pages 46-48"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}